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Conserved domains on  [gi|1799410209|gb|QHL51976|]
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ABC transporter permease subunit [Staphylococcus aureus]

Protein Classification

sugar ABC transporter permease( domain architecture ID 10790449)

sugar ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of sugar substrates including oligosaccharides and maltodextrin

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0008643
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 1-279 8.51e-138

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


:

Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 389.51  E-value: 8.51e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   1 MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYGAKMIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVAS 80
Cdd:COG3833     6 SRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPENFTLENYKKLFTE--TPFLRWFLNSLIVAV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  81 ANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVK 160
Cdd:COG3833    84 VTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 161 GYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINDKYA 240
Cdd:COG3833   164 GYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRN 243

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1799410209 241 NNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:COG3833   244 TNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
 
Name Accession Description Interval E-value
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 1-279 8.51e-138

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 389.51  E-value: 8.51e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   1 MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYGAKMIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVAS 80
Cdd:COG3833     6 SRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPENFTLENYKKLFTE--TPFLRWFLNSLIVAV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  81 ANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVK 160
Cdd:COG3833    84 VTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 161 GYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINDKYA 240
Cdd:COG3833   164 GYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRN 243

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1799410209 241 NNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:COG3833   244 TNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
11-279 2.40e-53

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 175.28  E-value: 2.40e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  11 IGIYSFIAmmfvIILYPLLWTFGISLNPGtNLYGAKMIPDNATFKNYAFLLFDDSSQ-----------YLTWYKNTLIVA 79
Cdd:PRK10998   18 LLLLGFIA----LIMFPLLMVIAISLREG-NFATGSLIPEQISWEHWKLALGFSVEHadgrvtpppfpVLLWLWNSVKVA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  80 SANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGL------LDSLFGLTLVYIGGsIP 153
Cdd:PRK10998   93 GITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQyipfigLNTHGGVIFAYLGG-IA 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 154 MNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFN 233
Cdd:PRK10998  172 LHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQ 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1799410209 234 FIndkYANNFTV--FAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:PRK10998  252 YL---NPQNYLWgdFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-257 1.75e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 64.61  E-value: 1.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  74 NTLIVASANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYI----G 149
Cdd:cd06261     3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALilalL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 150 GSIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPkILLRSPEKFTLAV 229
Cdd:cd06261    83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV-SFLGGGEAPGPGT 161

                         170       180
                  ....*....|....*....|....*...
gi 1799410209 230 GLFNFINDKYANNFTVFAAGAIMIAVPI 257
Cdd:cd06261   162 GLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 90-272 2.22e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.77  E-value: 2.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  90 VTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVKGYFDTIPKE 169
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 170 LDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINdkYANNFTVFAAG 249
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYD--YPEIQGPVLAA 159

                         170       180
                  ....*....|....*....|...
gi 1799410209 250 AIMIAVpIAIVFLFLQRYLVSGL 272
Cdd:pfam00528 160 ALILLL-LNLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 7-277 1.75e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 45.83  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   7 ILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNlygakmipDNATFKNYAFLLfdDSSQYLTWYKNTLIVASANALFS 86
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDG--------DFIGLANFAEYF--ATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  87 VIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVY----IGGSIPMNAF----- 157
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIYgfwgIVIGEVFYTFphalm 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 158 -LVKGyFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKIL-----LRSPEKFTLAVGL 231
Cdd:TIGR03262 151 iLVTA-LSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIggdynVLATDIYKQVIGQ 229

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1799410209 232 fnfindkyaNNFTVFAAGAIMIAVPIAIVFL---FLQRYLVSGLTTGAT 277
Cdd:TIGR03262 230 ---------QNFPMGAVVGVLLLLPALLAFGidrAIQRRQRAQLSSRSV 269
 
Name Accession Description Interval E-value
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 1-279 8.51e-138

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 389.51  E-value: 8.51e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   1 MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYGAKMIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVAS 80
Cdd:COG3833     6 SRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPENFTLENYKKLFTE--TPFLRWFLNSLIVAV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  81 ANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVK 160
Cdd:COG3833    84 VTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMK 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 161 GYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINDKYA 240
Cdd:COG3833   164 GYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRN 243

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1799410209 241 NNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:COG3833   244 TNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-279 9.49e-82

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 247.32  E-value: 9.49e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   2 TKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLY--GAKMIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVA 79
Cdd:COG0395     6 RRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFsgPPSLLPSEFTLENYRAAFTD--GPFGRYLLNSLIVA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  80 SANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLV 159
Cdd:COG0395    84 VVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 160 KGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINDkY 239
Cdd:COG0395   164 RQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQ-Y 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1799410209 240 ANNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:COG0395   243 GTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
11-279 2.40e-53

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 175.28  E-value: 2.40e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  11 IGIYSFIAmmfvIILYPLLWTFGISLNPGtNLYGAKMIPDNATFKNYAFLLFDDSSQ-----------YLTWYKNTLIVA 79
Cdd:PRK10998   18 LLLLGFIA----LIMFPLLMVIAISLREG-NFATGSLIPEQISWEHWKLALGFSVEHadgrvtpppfpVLLWLWNSVKVA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  80 SANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGL------LDSLFGLTLVYIGGsIP 153
Cdd:PRK10998   93 GITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQyipfigLNTHGGVIFAYLGG-IA 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 154 MNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFN 233
Cdd:PRK10998  172 LHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQ 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1799410209 234 FIndkYANNFTV--FAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:PRK10998  252 YL---NPQNYLWgdFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 5-264 3.42e-25

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 100.57  E-value: 3.42e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   5 KNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYgakMIPDNATFKNYAFLLfdDSSQYLTWYKNTLIVASANAL 84
Cdd:COG1177     1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWFLT---FPPEGFTLRWYAELF--SDPRLLDALLNSLLIALLSTL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  85 FSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVKGYFD 164
Cdd:COG1177    76 LATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLARLQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 165 TIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPkILLRSPEKFTLAVGLFNFIndKYANNFT 244
Cdd:COG1177   156 GFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVIT-LFLAGPGVTTLPVYIYSMI--RRGISPE 232

                         250       260
                  ....*....|....*....|
gi 1799410209 245 VFAAGAIMIAVPIAIVFLFL 264
Cdd:COG1177   233 INALSTLLILLSLLLLLLAE 252
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
1-279 2.77e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 81.36  E-value: 2.77e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   1 MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGtnlygakmipdnatFKNYAFLLFDDSSQYLTWykNTLIVAS 80
Cdd:COG1178     1 MSTRPRRRPRLLLLLLALLLALLVLLPLLALLLRAFTDG--------------LANFWALLSDPYLWRALG--NTLLLAL 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  81 ANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSL----FGLTLVYIGG------ 150
Cdd:COG1178    65 LVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLlralFGLEPPDIYGlggiil 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 151 -----SIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILlrSPEKF 225
Cdd:COG1178   145 vlvlfNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGYT 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1799410209 226 TLAVGLFNFINdkYANNFTvFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGATKG 279
Cdd:COG1178   223 TLTTAIYQAWL--GDFDLG-AAAALALVLLLLVLLLLLLERRLRRRRRYATVGG 273
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
16-268 1.68e-16

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 77.48  E-value: 1.68e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  16 FIAMMFVIILYPLLWTFGISLnpgTNLYGAKMIPDNATFKNYAFLLFDDssQYLTWYKNTLIVASANALFSVIFVTLTAY 95
Cdd:COG1175    27 ALLLLLVFVLYPLLYTLYLSF---TDWNLLGPPPEFVGLDNYARLFTDP--RFWNALGNTLLFTVVSVPLQLVLGLLLAL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  96 AFSRyRFVGRKYglitFLILQMFPVLMAMVAI-----YILLNTIGLLD-------------------SLFGLTLVYIGGS 151
Cdd:COG1175   102 LLNR-KLRGRGF----FRTLFFLPWVISPVVValiwkWLFNPDYGLLNallgalglepinwlgdpslALPAVIIVTVWKG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 152 IPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLR-SPEKFTLAVG 230
Cdd:COG1175   177 TGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVLTGgGPGNSTTTLV 256

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1799410209 231 LFNFINDKYANNFTVFAAGAIMIAVPIAIVFLFLQRYL 268
Cdd:COG1175   257 LYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLL 294
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
74-272 1.69e-15

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 74.39  E-value: 1.69e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  74 NTLIVASANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIP 153
Cdd:PRK10973   79 NSFVMAFSITVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATA 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 154 mnAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFN 233
Cdd:PRK10973  159 --TFLFRQFFMTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKG 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1799410209 234 FI-NDKYANNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGL 272
Cdd:PRK10973  237 MIaTGEGTTEWNQVMAAMLLTLIPPVVIVLAMQRAFVRGL 276
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
8-268 3.27e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 75.20  E-value: 3.27e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   8 LKAIGIYSFIAMMFVIILYPLLWTFGISLNPGtnlygakmIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVASANALFSV 87
Cdd:COG1178   286 WRWLALALCLLLVLLGLLLPLLALLLWSLTKA--------LDDNLTLDNYRFVLLD--PSLLRALLNSLLLALLAALLAV 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  88 IFVTLTAYAFSRYRFVGRKY-GLITFLILQMFPVLMAmVAIYILLNTIGLLD---SLFGLTLVYIGGSIPMNAFLVKGYF 163
Cdd:COG1178   356 LLALLLAYLVRRRRGRLARLlDRLAMLPYAVPGIVLG-LGLLLLFNRPLPLLlygTLAILVLAYVVRFLPFALRSLEAAL 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 164 DTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPkILLRSPEKFTLAVGLFNFINDkyaNNF 243
Cdd:COG1178   435 AQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSAT-LLLRPPGFETLAVLIYQLASS---GRY 510

                         250       260
                  ....*....|....*....|....*
gi 1799410209 244 TVFAAGAIMIAVPIAIVFLFLQRYL 268
Cdd:COG1178   511 GEAAALALLLVLVSLLPVLLLERLL 535
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 16-268 5.86e-13

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 67.48  E-value: 5.86e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  16 FIAMMFVIILYPLLWTFGISLNPGTNLYGakmIPDNATFKNYAFLLFDdsSQYLTWYKNTLIVASANALFSVIFVTLTAY 95
Cdd:COG1176    18 ALLWLLLFFVLPLLLLLVYSFTTRDPYGG---VVPGFTLENYARLFTD--PLYLKVLLRTLWIALLTTLICLLLGYPIAY 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  96 AFSRYRFVGRKYgLITFLILQMF-PVLMAMVAIYILLNTIGLLDSL-----------------FGLTLVYIGGSIPMNAF 157
Cdd:COG1176    93 FLARAPPRWRNL-LLLLVILPFWtSFLVRTYAWIVLLGRNGLLNSLllalglideplrllyteFAVVIGLVYVYLPFMVL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 158 LVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKiLLRSPEKFTLAVGLFNFINd 237
Cdd:COG1176   172 PLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPA-LLGGGKVLMIGNLIYQQFL- 249

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1799410209 238 kYANNFTVFAAGAIMIAVPIAIVFLFLQRYL 268
Cdd:COG1176   250 -SALNWPLAAALAVVLLLIVLLVLLLYLRLL 279
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-257 1.75e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 64.61  E-value: 1.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  74 NTLIVASANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYI----G 149
Cdd:cd06261     3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALilalL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 150 GSIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPkILLRSPEKFTLAV 229
Cdd:cd06261    83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV-SFLGGGEAPGPGT 161

                         170       180
                  ....*....|....*....|....*...
gi 1799410209 230 GLFNFINDKYANNFTVFAAGAIMIAVPI 257
Cdd:cd06261   162 GLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 90-272 2.22e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 55.77  E-value: 2.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  90 VTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVKGYFDTIPKE 169
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 170 LDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKILLRSPEKFTLAVGLFNFINdkYANNFTVFAAG 249
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYD--YPEIQGPVLAA 159

                         170       180
                  ....*....|....*....|...
gi 1799410209 250 AIMIAVpIAIVFLFLQRYLVSGL 272
Cdd:pfam00528 160 ALILLL-LNLLVDILQRLLDPRV 181
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 53-201 2.31e-07

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 50.75  E-value: 2.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  53 TFKNYAFLLFDDSSQYLTWykNTLIVASANALFSVIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLN 132
Cdd:PRK09500   42 TTKWYELLFNNDSLLQAAQ--HSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFM 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1799410209 133 TIGLLDSLFGLTLVYIGGSIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPilAVVA 201
Cdd:PRK09500  120 LLGIQLGFWSLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALP--AVAA 186
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
67-202 9.34e-06

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 45.90  E-value: 9.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  67 QYLTWYKNTLIVASANALFSVIFVTLTAYAFSRYRFVGRKygLITFLILQMF--PVLMAMVAIYILLNTIGLLDSL---F 141
Cdd:PRK10971   55 QVVAAYKVTLLSAFVASIFNAVFGLLMAWILTRYRFPGRT--LLDALMDLPFalPTAVAGLTLASLFSVNGWYGEWlakF 132

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1799410209 142 GLTLVY--IG-------GSIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLP-LAKPILAVVAL 202
Cdd:PRK10971  133 DIKVTYtwLGiavamafTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPeLSPALLAGVAL 203
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 7-277 1.75e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 45.83  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209   7 ILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNlygakmipDNATFKNYAFLLfdDSSQYLTWYKNTLIVASANALFS 86
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDG--------DFIGLANFAEYF--ATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  87 VIFVTLTAYAFSRYRFVGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVY----IGGSIPMNAF----- 157
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIYgfwgIVIGEVFYTFphalm 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 158 -LVKGyFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKIL-----LRSPEKFTLAVGL 231
Cdd:TIGR03262 151 iLVTA-LSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIggdynVLATDIYKQVIGQ 229

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1799410209 232 fnfindkyaNNFTVFAAGAIMIAVPIAIVFL---FLQRYLVSGLTTGAT 277
Cdd:TIGR03262 230 ---------QNFPMGAVVGVLLLLPALLAFGidrAIQRRQRAQLSSRSV 269
cysT CHL00187
sulfate transport protein; Provisional
 72-225 2.20e-03

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 38.46  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  72 YKNTLIVASANALFSVIFVTLTAYAFSRYRFVGRKYGL-ITFLILQMFPVL--MAMVAIYILLNTIGLLDSLFGLTLVYI 148
Cdd:CHL00187   57 YSLTLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDaAVDLPFALPTSVagLTLATVYGDNGWIGHLLSHLGIQIVFT 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 149 GGSIPMNAFLVKGYF---------DTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNF---MG--------- 207
Cdd:CHL00187  137 KLGVLLAMIFVSFPFvvrtiqpvlQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFsraIGeygsiviis 216

                         170       180
                  ....*....|....*....|.
gi 1799410209 208 ---PFMDFILPKILLRSPEKF 225
Cdd:CHL00187  217 sniPFKDLVASVLIFQSLEQY 237
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
61-211 4.18e-03

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 37.88  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209  61 LFDDS---SQYLTWYKNTLIVASANALFSVIFVTLTAYAFSRYRFvgrkYGLITFLILQMFPVLMAMVAIYILLNTIGLL 137
Cdd:PRK10561   47 LFHDSyylDSFWTTIKFSTLVTVSGLLVSLFFAALVDYVVRGSRF----YQTLMLLPYAVAPAVAAVLWIFLFNPGRGLI 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799410209 138 ------------------DSLFGLTLVYIGGSIPMNAFLVKGYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAV 199
Cdd:PRK10561  123 thflaefgydwnhaqnsgQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFF 202

                         170
                  ....*....|..
gi 1799410209 200 VALFNFMGPFMD 211
Cdd:PRK10561  203 LLVVNLVYAFFD 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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