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Conserved domains on  [gi|1790835711|gb|QHC37657|]
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CidA/LrgA family protein (plasmid) [Komagataeibacter xylinus]

Protein Classification

CidA/LrgA family protein( domain architecture ID 10003619)

CidA/LrgA family protein similar to Staphylococcus holin-like protein CidA that increases the activity of extracellular murein hydrolases, possibly by mediating their export via hole formation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
1-126 8.29e-14

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


:

Pssm-ID: 440990  Cd Length: 120  Bit Score: 62.82  E-value: 8.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790835711   1 MIAAIGIVLACQLLGEIVSRSLVPPVPGPVVGLLVLLLALFAVGTRSKvsedrpkalPIERVSDVLLGSLGLFFVPATVG 80
Cdd:COG1380     1 MLRQLAILLLFQLLGELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLE---------WVEPGADFLLRHLSLLFVPAGVG 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1790835711  81 VIQTADVLSRYGGGLLLAVAGSTILALVSTVVVFIGLSRLMGHSGE 126
Cdd:COG1380    72 VMNYLDLLSAEGLPILLAIVVSTLLVLAVTGLVVQLLLRRKEKKGE 117
 
Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
1-126 8.29e-14

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


Pssm-ID: 440990  Cd Length: 120  Bit Score: 62.82  E-value: 8.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790835711   1 MIAAIGIVLACQLLGEIVSRSLVPPVPGPVVGLLVLLLALFAVGTRSKvsedrpkalPIERVSDVLLGSLGLFFVPATVG 80
Cdd:COG1380     1 MLRQLAILLLFQLLGELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLE---------WVEPGADFLLRHLSLLFVPAGVG 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1790835711  81 VIQTADVLSRYGGGLLLAVAGSTILALVSTVVVFIGLSRLMGHSGE 126
Cdd:COG1380    72 VMNYLDLLSAEGLPILLAIVVSTLLVLAVTGLVVQLLLRRKEKKGE 117
LrgA pfam03788
LrgA family; This family is uncharacterized. It contains the protein LrgA that has been ...
 59-114 1.99e-10

LrgA family; This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.


Pssm-ID: 461050  Cd Length: 94  Bit Score: 53.52  E-value: 1.99e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1790835711  59 IERVSDVLLGSLGLFFVPATVGVIQTADVLSRYGGGLLLAVAGSTILALVSTVVVF 114
Cdd:pfam03788  39 VEEAADFLLRHMPLFFVPAGVGLMTYLDLLKAEGLPILVIIVVSTVLVLAVTGLVV 94
PRK01658 PRK01658
CidA/LrgA family holin-like protein;
59-110 1.50e-05

CidA/LrgA family holin-like protein;


Pssm-ID: 167253  Cd Length: 122  Bit Score: 41.17  E-value: 1.50e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1790835711  59 IERVSDVLLGSLGLFFVPATVGVIQTADVLSRYGGGLLLAVAGSTILALVST 110
Cdd:PRK01658   55 IELGAETLLAELPLFFIPSAVGVMNYGDFLSSKGISLFLVVVISTFVVMIVT 106
 
Name Accession Description Interval E-value
YohJ COG1380
Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];
1-126 8.29e-14

Putative effector of murein hydrolase LrgA, UPF0299 family [General function prediction only];


Pssm-ID: 440990  Cd Length: 120  Bit Score: 62.82  E-value: 8.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790835711   1 MIAAIGIVLACQLLGEIVSRSLVPPVPGPVVGLLVLLLALFAVGTRSKvsedrpkalPIERVSDVLLGSLGLFFVPATVG 80
Cdd:COG1380     1 MLRQLAILLLFQLLGELLSRLLGLPIPGSVIGMLLLFLLLALGIIKLE---------WVEPGADFLLRHLSLLFVPAGVG 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1790835711  81 VIQTADVLSRYGGGLLLAVAGSTILALVSTVVVFIGLSRLMGHSGE 126
Cdd:COG1380    72 VMNYLDLLSAEGLPILLAIVVSTLLVLAVTGLVVQLLLRRKEKKGE 117
LrgA pfam03788
LrgA family; This family is uncharacterized. It contains the protein LrgA that has been ...
 59-114 1.99e-10

LrgA family; This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.


Pssm-ID: 461050  Cd Length: 94  Bit Score: 53.52  E-value: 1.99e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1790835711  59 IERVSDVLLGSLGLFFVPATVGVIQTADVLSRYGGGLLLAVAGSTILALVSTVVVF 114
Cdd:pfam03788  39 VEEAADFLLRHMPLFFVPAGVGLMTYLDLLKAEGLPILVIIVVSTVLVLAVTGLVV 94
PRK01658 PRK01658
CidA/LrgA family holin-like protein;
59-110 1.50e-05

CidA/LrgA family holin-like protein;


Pssm-ID: 167253  Cd Length: 122  Bit Score: 41.17  E-value: 1.50e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1790835711  59 IERVSDVLLGSLGLFFVPATVGVIQTADVLSRYGGGLLLAVAGSTILALVST 110
Cdd:PRK01658   55 IELGAETLLAELPLFFIPSAVGVMNYGDFLSSKGISLFLVVVISTFVVMIVT 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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