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Conserved domains on  [gi|1776287775|gb|QGK76610|]
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hypothetical protein GIY83_21815 [Flavobacterium sp. SLB02]

Protein Classification

cytochrome c3 family protein( domain architecture ID 10560556)

class III cytochrome c (c3) family containing doubled CXXCH motif associated with heme binding, similar to Geobacter sulfurreducens OmcE

CATH:  3.90.10.10
Gene Ontology:  GO:0009055|GO:0020037
PubMed:  16964504|4364940
SCOP:  3002451

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Paired_CXXCH_1 pfam09699
Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids ...
 313-344 2.39e-04

Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids that contains, among other motifs, two copies of the motif CXXCH associated with haem binding. This domain is predicted to be a high molecular weight c-type cytochrome and is often found in multiple copies. Members are found mostly in species of Shewanella, Geobacter, and Vibrio.


:

Pssm-ID: 462851 [Multi-domain]  Cd Length: 41  Bit Score: 38.49  E-value: 2.39e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1776287775 313 DCITCHNPHENASKNL--ASYSKICVSCHQDLKH 344
Cdd:pfam09699   8 DCTSCHNPHGSPNPKLlkAKGNALCYGCHDEKAA 41
decahem_SO1788 super family cl28266
decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella ...
 141-339 1.00e-03

decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella oneidensis MR-1, and its paralog SO_1779 (OmcA), with which it intteracts, are large decaheme proteins, about 900 amino acids in length, involved in the use of manganese [Mn(III/IV)] and iron [Fe(III)] as terminal electron acceptors. This model represents these and similar decaheme proteins, found also in Rhodoferax ferrireducens DSM 15236, Aeromonas hydrophila ATCC7966, and a few other bacterial species. [Energy metabolism, Electron transport]


The actual alignment was detected with superfamily member TIGR03507:

Pssm-ID: 274617 [Multi-domain]  Cd Length: 659  Bit Score: 41.36  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 141 YNAINSWATSPGFPADKPYFD-----------RKVVKD--CYACHSSNI----RSRSVN-----QNPEevnFLSAEVEDV 198
Cdd:TIGR03507 120 QLGRNAVNGTLGAPVANPVFDfipaggapaatRNVVSIaaCNSCHGELAlhggRRIDVElcvtcHNPS---TADPGSGNS 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 199 IDKKTIVYGIdcercHGpAKKHADFHLKNPNIKVANSIVSYKTLNRQQKLDACALCHSGNDGMKmksrfdfKPGDNLSef 278
Cdd:TIGR03507 197 LDFAVMIHKI-----HM-GKKLPSVDSGDPYIGYGNAKIDFSDVGFPQDPRNCTTCHSGANTKT-------ADADNWK-- 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1776287775 279 yrstRNPNdttfdvhgnqfrlmsqskcfikseKMDCITCHN-----PHENASKNLASYSKICVSCH 339
Cdd:TIGR03507 262 ----TVPS------------------------MAACGSCHDnvnfaTGANHVNQTQADDTQCAACH 299
 
Name Accession Description Interval E-value
Paired_CXXCH_1 pfam09699
Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids ...
 313-344 2.39e-04

Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids that contains, among other motifs, two copies of the motif CXXCH associated with haem binding. This domain is predicted to be a high molecular weight c-type cytochrome and is often found in multiple copies. Members are found mostly in species of Shewanella, Geobacter, and Vibrio.


Pssm-ID: 462851 [Multi-domain]  Cd Length: 41  Bit Score: 38.49  E-value: 2.39e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1776287775 313 DCITCHNPHENASKNL--ASYSKICVSCHQDLKH 344
Cdd:pfam09699   8 DCTSCHNPHGSPNPKLlkAKGNALCYGCHDEKAA 41
paired_CXXCH_1 TIGR01905
doubled CXXCH domain; This model represents a domain of about 41 amino acids that contains, ...
 313-344 3.98e-04

doubled CXXCH domain; This model represents a domain of about 41 amino acids that contains, among other motifs, two copies of the motif CXXCH associated with heme binding. Almost every member of this family has at least three copies of this domain (at least six copies of CXXCH) is predicted to be a high molecular weight c-type cytochrome. Members are found mostly in species of Shewanella, Geobacter, and Vibrio.


Pssm-ID: 213663 [Multi-domain]  Cd Length: 41  Bit Score: 37.77  E-value: 3.98e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1776287775 313 DCITCHNPHENASKNL--ASYSKICVSCHQDLKH 344
Cdd:TIGR01905   8 DCTSCHDPHGSPEPKLlkEDGPDLCLGCHDDAAL 41
decahem_SO1788 TIGR03507
decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella ...
 141-339 1.00e-03

decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella oneidensis MR-1, and its paralog SO_1779 (OmcA), with which it intteracts, are large decaheme proteins, about 900 amino acids in length, involved in the use of manganese [Mn(III/IV)] and iron [Fe(III)] as terminal electron acceptors. This model represents these and similar decaheme proteins, found also in Rhodoferax ferrireducens DSM 15236, Aeromonas hydrophila ATCC7966, and a few other bacterial species. [Energy metabolism, Electron transport]


Pssm-ID: 274617 [Multi-domain]  Cd Length: 659  Bit Score: 41.36  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 141 YNAINSWATSPGFPADKPYFD-----------RKVVKD--CYACHSSNI----RSRSVN-----QNPEevnFLSAEVEDV 198
Cdd:TIGR03507 120 QLGRNAVNGTLGAPVANPVFDfipaggapaatRNVVSIaaCNSCHGELAlhggRRIDVElcvtcHNPS---TADPGSGNS 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 199 IDKKTIVYGIdcercHGpAKKHADFHLKNPNIKVANSIVSYKTLNRQQKLDACALCHSGNDGMKmksrfdfKPGDNLSef 278
Cdd:TIGR03507 197 LDFAVMIHKI-----HM-GKKLPSVDSGDPYIGYGNAKIDFSDVGFPQDPRNCTTCHSGANTKT-------ADADNWK-- 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1776287775 279 yrstRNPNdttfdvhgnqfrlmsqskcfikseKMDCITCHN-----PHENASKNLASYSKICVSCH 339
Cdd:TIGR03507 262 ----TVPS------------------------MAACGSCHDnvnfaTGANHVNQTQADDTQCAACH 299
 
Name Accession Description Interval E-value
Paired_CXXCH_1 pfam09699
Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids ...
 313-344 2.39e-04

Doubled CXXCH motif (Paired_CXXCH_1); This entry represents a domain of about 41 amino acids that contains, among other motifs, two copies of the motif CXXCH associated with haem binding. This domain is predicted to be a high molecular weight c-type cytochrome and is often found in multiple copies. Members are found mostly in species of Shewanella, Geobacter, and Vibrio.


Pssm-ID: 462851 [Multi-domain]  Cd Length: 41  Bit Score: 38.49  E-value: 2.39e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1776287775 313 DCITCHNPHENASKNL--ASYSKICVSCHQDLKH 344
Cdd:pfam09699   8 DCTSCHNPHGSPNPKLlkAKGNALCYGCHDEKAA 41
paired_CXXCH_1 TIGR01905
doubled CXXCH domain; This model represents a domain of about 41 amino acids that contains, ...
 313-344 3.98e-04

doubled CXXCH domain; This model represents a domain of about 41 amino acids that contains, among other motifs, two copies of the motif CXXCH associated with heme binding. Almost every member of this family has at least three copies of this domain (at least six copies of CXXCH) is predicted to be a high molecular weight c-type cytochrome. Members are found mostly in species of Shewanella, Geobacter, and Vibrio.


Pssm-ID: 213663 [Multi-domain]  Cd Length: 41  Bit Score: 37.77  E-value: 3.98e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1776287775 313 DCITCHNPHENASKNL--ASYSKICVSCHQDLKH 344
Cdd:TIGR01905   8 DCTSCHDPHGSPEPKLlkEDGPDLCLGCHDDAAL 41
decahem_SO1788 TIGR03507
decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella ...
 141-339 1.00e-03

decaheme c-type cytochrome, OmcA/MtrC family; The protein SO_1778 (MtrC) of Shewanella oneidensis MR-1, and its paralog SO_1779 (OmcA), with which it intteracts, are large decaheme proteins, about 900 amino acids in length, involved in the use of manganese [Mn(III/IV)] and iron [Fe(III)] as terminal electron acceptors. This model represents these and similar decaheme proteins, found also in Rhodoferax ferrireducens DSM 15236, Aeromonas hydrophila ATCC7966, and a few other bacterial species. [Energy metabolism, Electron transport]


Pssm-ID: 274617 [Multi-domain]  Cd Length: 659  Bit Score: 41.36  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 141 YNAINSWATSPGFPADKPYFD-----------RKVVKD--CYACHSSNI----RSRSVN-----QNPEevnFLSAEVEDV 198
Cdd:TIGR03507 120 QLGRNAVNGTLGAPVANPVFDfipaggapaatRNVVSIaaCNSCHGELAlhggRRIDVElcvtcHNPS---TADPGSGNS 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1776287775 199 IDKKTIVYGIdcercHGpAKKHADFHLKNPNIKVANSIVSYKTLNRQQKLDACALCHSGNDGMKmksrfdfKPGDNLSef 278
Cdd:TIGR03507 197 LDFAVMIHKI-----HM-GKKLPSVDSGDPYIGYGNAKIDFSDVGFPQDPRNCTTCHSGANTKT-------ADADNWK-- 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1776287775 279 yrstRNPNdttfdvhgnqfrlmsqskcfikseKMDCITCHN-----PHENASKNLASYSKICVSCH 339
Cdd:TIGR03507 262 ----TVPS------------------------MAACGSCHDnvnfaTGANHVNQTQADDTQCAACH 299
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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