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Conserved domains on  [gi|1760105096|gb|QFJ54539|]
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carbohydrate ABC transporter permease [Pseudobutyrivibrio xylanivorans]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 22-299 3.94e-78

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 238.84  E-value: 3.94e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDPITLQNKGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG0395    18 YLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITMFFGG--GLIPTYILISRLGMLDSMWAVILPGSF--SVWNMIIARTYFQGVPSELREA 177
Cdd:COG0395    98 AYALARFRFRGRKLLFLLILATLMIPGqvLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEA 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 178 AEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPLQLVLRSILIQNQPEAGMIAdmqstaq 257
Cdd:COG0395   178 ARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLM------- 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1760105096 258 raqlaellkyATIIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:COG0395   251 ----------AAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 22-299 3.94e-78

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 238.84  E-value: 3.94e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDPITLQNKGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG0395    18 YLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITMFFGG--GLIPTYILISRLGMLDSMWAVILPGSF--SVWNMIIARTYFQGVPSELREA 177
Cdd:COG0395    98 AYALARFRFRGRKLLFLLILATLMIPGqvLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEA 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 178 AEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPLQLVLRSILIQNQPEAGMIAdmqstaq 257
Cdd:COG0395   178 ARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLM------- 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1760105096 258 raqlaellkyATIIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:COG0395   251 ----------AAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
17-299 1.55e-13

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 69.35  E-value: 1.55e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  17 LLLTGYFLLGlFVLAIIVPMVYIVLASFI-----------DPITLQNKGLTFDFSkwTLTAYERVLSNK---QIWvgFKN 82
Cdd:PRK10998   13 LFATHLLLLG-FIALIMFPLLMVIAISLRegnfatgslipEQISWEHWKLALGFS--VEHADGRVTPPPfpvLLW--LWN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  83 SVVYSLVFTFVSVFVTLLCAYPMSRPDFRGKG-IFNTIFIITMFFGG-GLIPTYILISRLGM------LDSMWAVILPG- 153
Cdd:PRK10998   88 SVKVAGITAIGIVALSTTCAYAFARMRFKGKAtLLKGMLIFQMFPAVlSLVALYALFDRLGQyipfigLNTHGGVIFAYl 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 154 ---SFSVWNMiiaRTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQP 230
Cdd:PRK10998  168 ggiALHVWTI---KGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYT 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1760105096 231 LQLVLRSILiqnQPEAGMIADMQSTAqraqlaellkyatiIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:PRK10998  245 LAVGMQQYL---NPQNYLWGDFAAAA--------------VLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-250 1.89e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  80 FKNSVVYSLVFTFVSVFVTLLCAYPMSRPDFRGKGIFNTIF--------IITMFFGGGLIPTYILISRLGMLDSMWAVIL 151
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIdlllslpsLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 152 PGSFSVWNMIIARTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPL 231
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*....
gi 1760105096 232 QLVLRSILIQNQPEAGMIA 250
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAA 179
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-214 2.05e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 41.52  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 103 YPMSRPDFRGKGIFNTIFIITMFFGGGLIPTYILISRLGMLDSMWAVILPGSFSVWNMIIARTYFQGVPSELREAAEVDG 182
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1760105096 183 ASEVVYFFKILLPVCVPVIAVLCLWQFVGMWN 214
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALG 122
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 27-197 2.81e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  27 LFVLAIIVPMVYIVLASFidpitlQNKGLTFDfskwTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLCAYPMS 106
Cdd:TIGR03262  13 ALLLFLLLPLLALLTKSV------YDSDGDFI----GLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 107 RPDFRGKGIFNTIFIITMfFGGGLIPTYILISRLGMLDSMWAVILPGS-FSVWNMIIARTY-------------FQGVPS 172
Cdd:TIGR03262  83 RSRIPGKGAFRLVALLPL-LAPSLLPAISLIYLFGNQGLLKGLLGGFSiYGFWGIVIGEVFytfphalmilvtaLSLADG 161

                         170       180
                  ....*....|....*....|....*
gi 1760105096 173 ELREAAEVDGASEVVYFFKILLPVC 197
Cdd:TIGR03262 162 RLYEAARAMGASPWRTFFTVTLPGA 186
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 22-299 3.94e-78

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 238.84  E-value: 3.94e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDPITLQNKGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG0395    18 YLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITMFFGG--GLIPTYILISRLGMLDSMWAVILPGSF--SVWNMIIARTYFQGVPSELREA 177
Cdd:COG0395    98 AYALARFRFRGRKLLFLLILATLMIPGqvLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEA 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 178 AEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPLQLVLRSILIQNQPEAGMIAdmqstaq 257
Cdd:COG0395   178 ARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLM------- 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1760105096 258 raqlaellkyATIIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:COG0395   251 ----------AAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 22-299 1.60e-45

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 155.31  E-value: 1.60e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDPITLQnkGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG3833    19 HLVLIILAIIALFPILWVVSASFNPGGSLY--SSSLIPENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAALA 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITMFFGG--GLIPTYILISRLGMLDSMWAVILPGS-----FSVWNMiiaRTYFQGVPSEL 174
Cdd:COG3833    97 AYAFSRFRFKGRKAGLLALLLLQMFPAflALVALYLLLSALGLLNTLLGLILVYLggaipFNTWLM---KGYFDTIPKEL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 175 REAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPLQLVLRSiliqnqpeagMIADMQS 254
Cdd:COG3833   174 DEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYS----------FVSDQRN 243

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1760105096 255 TaQRAQLAellkyATIIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:COG3833   244 T-NWGVFA-----AGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 22-202 1.40e-20

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 88.63  E-value: 1.40e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDpitlqNKGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG1177    10 RLFLALVLLFLYLPILVLVLYSFND-----SWFLTFPPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITMFFGG---GlIPTYILISRLGMLDSMWAVILpgSFSVWNM----IIARTYFQGVPSEL 174
Cdd:COG1177    85 ALALARYRFRGRRLLLALLLLPLVVPGivlG-VALLLLFSALGLSGGLWGLIL--AHVVFTLpfvvLVVLARLQGFDPSL 161

                         170       180
                  ....*....|....*....|....*...
gi 1760105096 175 REAAEVDGASEVVYFFKILLPVCVPVIA 202
Cdd:COG1177   162 EEAARDLGASPWQTFRRVTLPLIAPGIL 189
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
19-216 4.48e-19

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 85.19  E-value: 4.48e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  19 LTGYFLLG----LFVLAIIVPMVYIVLASFidpitlQNKGLTFDFSKWT-LTAYERVLSNKQIWVGFKNSVVYSLVFTFV 93
Cdd:COG1175    18 LAAYLFLLpallLLLVFVLYPLLYTLYLSF------TDWNLLGPPPEFVgLDNYARLFTDPRFWNALGNTLLFTVVSVPL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  94 SVFVTLLCAYPMSRPdFRGKGIFNTIFIITMFFGG---GLIPTYILISRLGMLD-------------------SMWAVIL 151
Cdd:COG1175    92 QLVLGLLLALLLNRK-LRGRGFFRTLFFLPWVISPvvvALIWKWLFNPDYGLLNallgalglepinwlgdpslALPAVII 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 152 pgsFSVW-----NMIIARTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSY 216
Cdd:COG1175   171 ---VTVWkgtgfNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVF 237
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
23-202 8.75e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 71.35  E-value: 8.75e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  23 FLLGLFVLAIIVPMVYIVLASFIDPitlqnkgltfdfskwtLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLCA 102
Cdd:COG1178    15 LLALLLALLVLLPLLALLLRAFTDG----------------LANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 103 YPMSRPDFRGKGIFNTIFIITMFfggglIPTYI-------------LISRLGM---------LDSMWAVILpgSFSVWNM 160
Cdd:COG1178    79 WLLARTDFPGRRLLRWLLLLPLA-----LPPYVvalawialfgpngLLNTLLRalfgleppdIYGLGGIIL--VLVLFNY 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1760105096 161 ----IIARTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIA 202
Cdd:COG1178   152 pyvyLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIA 197
malG PRK10998
maltose ABC transporter permease MalG;
17-299 1.55e-13

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 69.35  E-value: 1.55e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  17 LLLTGYFLLGlFVLAIIVPMVYIVLASFI-----------DPITLQNKGLTFDFSkwTLTAYERVLSNK---QIWvgFKN 82
Cdd:PRK10998   13 LFATHLLLLG-FIALIMFPLLMVIAISLRegnfatgslipEQISWEHWKLALGFS--VEHADGRVTPPPfpvLLW--LWN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  83 SVVYSLVFTFVSVFVTLLCAYPMSRPDFRGKG-IFNTIFIITMFFGG-GLIPTYILISRLGM------LDSMWAVILPG- 153
Cdd:PRK10998   88 SVKVAGITAIGIVALSTTCAYAFARMRFKGKAtLLKGMLIFQMFPAVlSLVALYALFDRLGQyipfigLNTHGGVIFAYl 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 154 ---SFSVWNMiiaRTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQP 230
Cdd:PRK10998  168 ggiALHVWTI---KGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYT 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1760105096 231 LQLVLRSILiqnQPEAGMIADMQSTAqraqlaellkyatiIVSSLPLIVMYPFFQKYFDAGIMAGSIKG 299
Cdd:PRK10998  245 LAVGMQQYL---NPQNYLWGDFAAAA--------------VLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
22-203 4.84e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.95  E-value: 4.84e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  22 YFLLGLFVLAIIVPMVYIVLASFIDPITLQnkgltfdfskWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:COG1178   292 ALCLLLVLLGLLLPLLALLLWSLTKALDDN----------LTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLL 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNTIFIITM-----FFGGGLIPTYILISRLGMLDSMWAVILpgSFSVWNMIIA----RTYFQGVPS 172
Cdd:COG1178   362 AYLVRRRRGRLARLLDRLAMLPYavpgiVLGLGLLLLFNRPLPLLLYGTLAILVL--AYVVRFLPFAlrslEAALAQIDP 439

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1760105096 173 ELREAAEVDGASEVVYFFKILLPVCVPVIAV 203
Cdd:COG1178   440 SLEEAARSLGASPLRTLRRVTLPLLRPGLLA 470
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
77-227 7.34e-12

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 64.37  E-value: 7.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  77 WVGFKNSVVYSLVFTFVSVFVTLLCAYPMSRPDFRGKGI-FNTIFIITMF-FGGGLIPTYILISRLGMLDSMWAVILPGS 154
Cdd:PRK10973   74 GRMLLNSFVMAFSITVGKITVSMLSAFAIVWFRFPLRNLfFWMIFITLMLpVEVRIFPTVEVIANLKMLDSYAGLTLPLM 153

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1760105096 155 FSVWNMIIARTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVA 227
Cdd:PRK10973  154 ASATATFLFRQFFMTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVS 226
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 17-210 9.55e-11

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 61.32  E-value: 9.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  17 LLLTGYFLLGLFVLaiiVPMVYIVLASFIDPITLQNKGLTFdfskwTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVF 96
Cdd:COG1176    14 LLLPALLWLLLFFV---LPLLLLLVYSFTTRDPYGGVVPGF-----TLENYARLFTDPLYLKVLLRTLWIALLTTLICLL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  97 VTLLCAYPMSRPDFRGKGIFNTIFIITMFFGGgLIPTY---ILISRLGMLDS--MWAVILPGS----FSVWNMIIARTY- 166
Cdd:COG1176    86 LGYPIAYFLARAPPRWRNLLLLLVILPFWTSF-LVRTYawiVLLGRNGLLNSllLALGLIDEPlrllYTEFAVVIGLVYv 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1760105096 167 ------------FQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFV 210
Cdd:COG1176   165 ylpfmvlplyaaLEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFI 220
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 80-250 1.89e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.89e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  80 FKNSVVYSLVFTFVSVFVTLLCAYPMSRPDFRGKGIFNTIF--------IITMFFGGGLIPTYILISRLGMLDSMWAVIL 151
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIdlllslpsLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 152 PGSFSVWNMIIARTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVLCLWQFVGMWNSYFDAMIYINDVAKQPL 231
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*....
gi 1760105096 232 QLVLRSILIQNQPEAGMIA 250
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAA 179
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 25-199 7.24e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 58.61  E-value: 7.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  25 LGLFVLAIIVPMVYIVLASFIdPITlqnkGLTFDFSKWTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLCAYP 104
Cdd:COG0555     6 LPGFGLTLGLTLLYLSLIVLL-PLA----ALVLKAAGLGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 105 MSRPDFRGKGIFNTI-------------FIITMFFG-GGLIPTY-------ILISRLGMLDSMWAVILPgsFSVwnmIIA 163
Cdd:COG0555    81 LVRYRFPGKRLVDALvdlpfalptavagIALLLLFGpNGWLGQLlaplgikVAFTPLGIVLAQTFVSLP--FVV---RTV 155

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1760105096 164 RTYFQGVPSELREAAEVDGASEVVYFFKILLPVCVP 199
Cdd:COG0555   156 QPVLEELDPELEEAAATLGASRWQTFRRVILPLLLP 191
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 23-202 2.42e-05

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 44.98  E-value: 2.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  23 FLLGLFVLAIIVPMVYIVLASF-IDPITLQNKGLTFdfsKWtltaYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLC 101
Cdd:PRK09500    8 GFMTLVYAYLYIPIIILIVNSFnSSRFGINWKGFTT---KW----YELLFNNDSLLQAAQHSLTMAVFSATFATLIGSLT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 102 AYPMSRPDFRGKGIFNT-IFIITM----FFGGGLIPTYILIS-RLGMLDSMWAVI---LPgsFSVwnmIIARTYFQGVPS 172
Cdd:PRK09500   81 AVALYRYRFRGKKFVSGmLFVVMMspdiVMAISLLVLFMLLGiQLGFWSLLFAHItfcLP--FVV---VTVYSRLKGFDV 155

                         170       180       190
                  ....*....|....*....|....*....|
gi 1760105096 173 ELREAAEVDGASEVVYFFKILLPVCVPVIA 202
Cdd:PRK09500  156 RMLEAAKDLGASEFTILRKIILPLALPAVA 185
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 103-214 2.05e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 41.52  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 103 YPMSRPDFRGKGIFNTIFIITMFFGGGLIPTYILISRLGMLDSMWAVILPGSFSVWNMIIARTYFQGVPSELREAAEVDG 182
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1760105096 183 ASEVVYFFKILLPVCVPVIAVLCLWQFVGMWN 214
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALG 122
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 27-197 2.81e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  27 LFVLAIIVPMVYIVLASFidpitlQNKGLTFDfskwTLTAYERVLSNKQIWVGFKNSVVYSLVFTFVSVFVTLLCAYPMS 106
Cdd:TIGR03262  13 ALLLFLLLPLLALLTKSV------YDSDGDFI----GLANFAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096 107 RPDFRGKGIFNTIFIITMfFGGGLIPTYILISRLGMLDSMWAVILPGS-FSVWNMIIARTY-------------FQGVPS 172
Cdd:TIGR03262  83 RSRIPGKGAFRLVALLPL-LAPSLLPAISLIYLFGNQGLLKGLLGGFSiYGFWGIVIGEVFytfphalmilvtaLSLADG 161

                         170       180
                  ....*....|....*....|....*
gi 1760105096 173 ELREAAEVDGASEVVYFFKILLPVC 197
Cdd:TIGR03262 162 RLYEAARAMGASPWRTFFTVTLPGA 186
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 2-204 4.61e-03

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 38.15  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096   2 KKKSTFAKYDMTDKSLLLtgyFLLGLFVLAII---VPMVYIVLAsFIDpitlQNKGLTFDFSKWT-LTAYERVLSNKQIW 77
Cdd:COG4209    14 KRKKSFLKRLKRDWQLYL---MLLPGLIYLLIfsyLPMYGIVIA-FKD----YNPFKGIFGSPWVgLKNFKFLFSSPDFW 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1760105096  78 VGFKNSVVYSLVFTFVSVFVTLLCAYPMSR-PDFRGKGIFNTIF-------------IITMFFG--GGLIPTyiLISRLG 141
Cdd:COG4209    86 RVLRNTLLISLLKLVFGFPLPIILALLLNElRSKRFKKTVQTISylphflswvvvagIVYQFLSpdTGLVNQ--LLRALG 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1760105096 142 ------MLD-SMWAVILPGSfSVW-----NMIIartYF---QGVPSELREAAEVDGASEVVYFFKILLPVCVPVIAVL 204
Cdd:COG4209   164 gepinfLTEpKYFRPIYVFS-GIWkeagwGSII---YLaaiTGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTIVIL 237
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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