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Conserved domains on  [gi|1757094402|gb|QFG53368|]
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FAD-dependent monooxygenase [Chryseobacterium sp.]

Protein Classification

FAD-dependent oxidoreductase( domain architecture ID 11428987)

FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0071949|GO:0016491

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 95-469 1.04e-22

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


:

Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 98.47  E-value: 1.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  95 ALALACLHRGIPFTLYEKDNSFSDRAQGYGLTlQQASKAMVGFGINN--LEDGVVSTK-HIVHTPDGKIVGEWgmrkwlg 171
Cdd:COG0654    17 ALALALARAGIRVTVVERAPPPRPDGRGIALS-PRSLELLRRLGLWDrlLARGAPIRGiRVRDGSDGRVLARF------- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 172 nNSKAGSRRTNIHIARQILRSVLLRPLQNSG-SVKWGYELLQFnHCDDHSLNLKFRvndDVVVEKADLVIGADGIRSIVR 250
Cdd:COG0654    89 -DAAETGLPAGLVVPRADLERALLEAARALGvELRFGTEVTGL-EQDADGVTVTLA---DGRTLRADLVVGADGARSAVR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 251 RQiLGEETLPLRYLGCMVILGIcrlseigecdrslldsatvfqtangheriyimpyddvsvmwqlsfpipqeeAIALRnr 330
Cdd:COG0654   164 RL-LGIGFTGRDYPQRALWAGV---------------------------------------------------RTELR-- 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 331 gnealkqEAIRRtpWHDPIPQILNASDPSkisGYPVYDRDLLTSellnTSGASTLIGDAAHPMSPFKGQGANQALLDALS 410
Cdd:COG0654   190 -------ARLAA--AGPRLGELLELSPRS---AFPLRRRRAERW----RRGRVVLLGDAAHTMHPLGGQGANLALRDAAA 253

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1757094402 411 LAREITKGcsnpndWQDKDIREiILNRFEAEMLQRSAIKVEDSAAAAEYLHSELALFEA 469
Cdd:COG0654   254 LAWKLAAA------LRGRDDEA-ALARYERERRPRAARVQRAADALGRLFHPDSPPLRL 305
 
Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 95-469 1.04e-22

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 98.47  E-value: 1.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  95 ALALACLHRGIPFTLYEKDNSFSDRAQGYGLTlQQASKAMVGFGINN--LEDGVVSTK-HIVHTPDGKIVGEWgmrkwlg 171
Cdd:COG0654    17 ALALALARAGIRVTVVERAPPPRPDGRGIALS-PRSLELLRRLGLWDrlLARGAPIRGiRVRDGSDGRVLARF------- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 172 nNSKAGSRRTNIHIARQILRSVLLRPLQNSG-SVKWGYELLQFnHCDDHSLNLKFRvndDVVVEKADLVIGADGIRSIVR 250
Cdd:COG0654    89 -DAAETGLPAGLVVPRADLERALLEAARALGvELRFGTEVTGL-EQDADGVTVTLA---DGRTLRADLVVGADGARSAVR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 251 RQiLGEETLPLRYLGCMVILGIcrlseigecdrslldsatvfqtangheriyimpyddvsvmwqlsfpipqeeAIALRnr 330
Cdd:COG0654   164 RL-LGIGFTGRDYPQRALWAGV---------------------------------------------------RTELR-- 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 331 gnealkqEAIRRtpWHDPIPQILNASDPSkisGYPVYDRDLLTSellnTSGASTLIGDAAHPMSPFKGQGANQALLDALS 410
Cdd:COG0654   190 -------ARLAA--AGPRLGELLELSPRS---AFPLRRRRAERW----RRGRVVLLGDAAHTMHPLGGQGANLALRDAAA 253

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1757094402 411 LAREITKGcsnpndWQDKDIREiILNRFEAEMLQRSAIKVEDSAAAAEYLHSELALFEA 469
Cdd:COG0654   254 LAWKLAAA------LRGRDDEA-ALARYERERRPRAARVQRAADALGRLFHPDSPPLRL 305
PRK06753 PRK06753
hypothetical protein; Provisional
 97-415 4.15e-20

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 91.67  E-value: 4.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  97 ALACLHR-GIPFTLYEKDNSFSDRAQGYGLtlqqASKAMVGFGINNLEDGVvstkhivhTPDGKIVGEWGMRKWLGNN-S 174
Cdd:PRK06753   15 AAALLQEqGHEVKVFEKNESVKEVGAGIGI----GDNVIKKLGNHDLAKGI--------KNAGQILSTMNLLDDKGTLlN 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 175 KAG--SRRTNIHIARQILRSVLLRPLQNSgSVKWGYELLQFNHCDDHsLNLKFrvnDDVVVEKADLVIGADGIRSIVRRQ 252
Cdd:PRK06753   83 KVKlkSNTLNVTLHRQTLIDIIKSYVKED-AIFTGKEVTKIENETDK-VTIHF---ADGESEAFDLCIGADGIHSKVRQS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 253 ILGEETLplRYLGCMVILGIcrlseIGECDRSLLDSATVFQTANGheRIYIMPYDDVSVMWQLSFPIPQEEAiALRNRGN 332
Cdd:PRK06753  158 VNADSKV--RYQGYTCFRGL-----IDDIDLKLPDCAKEYWGTKG--RFGIVPLLNNQAYWFITINAKERDP-KYSSFGK 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 333 EALKQeaiRRTPWHDPIPQILNasdpsKISGYPVYDRDLLTSELLNT--SGASTLIGDAAHPMSPFKGQGANQALLDALS 410
Cdd:PRK06753  228 PHLQA---YFNHYPNEVREILD-----KQSETGILHHDIYDLKPLKSfvYGRIVLLGDAAHATTPNMGQGAGQAMEDAIV 299


                  ....*
gi 1757094402 411 LAREI 415
Cdd:PRK06753  300 LANCL 304
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 203-412 4.96e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 57.72  E-value: 4.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 203 SVKWGYELLQFNHCDDH-SLNLKFRVNDDVVVEKADLVIGADGIRSIVRRQI----LGEETLPLRYLGcmVILGICRLSE 277
Cdd:pfam01494 116 QVRFGTEVLSLEQDGDGvTAVVRDRRDGEEYTVRAKYLVGCDGGRSPVRKTLgiefEGFEGVPFGSLD--VLFDAPDLSD 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 278 IGEcdrsllDSATVFQTANGHERIY-IMPYD---DVSVMWQLSFPIPQEEaialrnRGNEALKQEAIRRTPWHDPIPQIL 353
Cdd:pfam01494 194 PVE------RAFVHYLIYAPHSRGFmVGPWRsagRERYYVQVPWDEEVEE------RPEEFTDEELKQRLRSIVGIDLAL 261

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1757094402 354 naSDPSKISGYPVYDRdlLTSELlnTSGASTLIGDAAHPMSPFKGQGANQALLDALSLA 412
Cdd:pfam01494 262 --VEILWKSIWGVASR--VATRY--RKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLA 314
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 235-441 4.35e-08

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 54.90  E-value: 4.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRQiLGEETLPLRYLGCMVIlgiCRLseigECDRSLLDSATVFQTANGHERIYIMPYDDVSVMWQ 314
Cdd:TIGR01988 151 RARLLVGADGANSKVRQL-AGIPTTGWDYGQSAVV---ANV----KHERPHQGTAWERFTPTGPLALLPLPDNRSSLVWT 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 315 LsfpiPQEEAIALRNRGNEALKQEAIRRTPWHDPIPQILnasdpSKISGYPvydrdlLTSELLNTSGAS--TLIGDAAHP 392
Cdd:TIGR01988 223 L----PPEEAERLLALSDEEFLAELQRAFGSRLGAITLV-----GERHAFP------LSLTHAKRYVAPrlALIGDAAHT 287

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1757094402 393 MSPFKGQGANQALLDALSLAREITKGCSNPNDWQDKDireiILNRFEAE 441
Cdd:TIGR01988 288 IHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLR----VLQRYERR 332
 
Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 95-469 1.04e-22

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 98.47  E-value: 1.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  95 ALALACLHRGIPFTLYEKDNSFSDRAQGYGLTlQQASKAMVGFGINN--LEDGVVSTK-HIVHTPDGKIVGEWgmrkwlg 171
Cdd:COG0654    17 ALALALARAGIRVTVVERAPPPRPDGRGIALS-PRSLELLRRLGLWDrlLARGAPIRGiRVRDGSDGRVLARF------- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 172 nNSKAGSRRTNIHIARQILRSVLLRPLQNSG-SVKWGYELLQFnHCDDHSLNLKFRvndDVVVEKADLVIGADGIRSIVR 250
Cdd:COG0654    89 -DAAETGLPAGLVVPRADLERALLEAARALGvELRFGTEVTGL-EQDADGVTVTLA---DGRTLRADLVVGADGARSAVR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 251 RQiLGEETLPLRYLGCMVILGIcrlseigecdrslldsatvfqtangheriyimpyddvsvmwqlsfpipqeeAIALRnr 330
Cdd:COG0654   164 RL-LGIGFTGRDYPQRALWAGV---------------------------------------------------RTELR-- 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 331 gnealkqEAIRRtpWHDPIPQILNASDPSkisGYPVYDRDLLTSellnTSGASTLIGDAAHPMSPFKGQGANQALLDALS 410
Cdd:COG0654   190 -------ARLAA--AGPRLGELLELSPRS---AFPLRRRRAERW----RRGRVVLLGDAAHTMHPLGGQGANLALRDAAA 253

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1757094402 411 LAREITKGcsnpndWQDKDIREiILNRFEAEMLQRSAIKVEDSAAAAEYLHSELALFEA 469
Cdd:COG0654   254 LAWKLAAA------LRGRDDEA-ALARYERERRPRAARVQRAADALGRLFHPDSPPLRL 305
PRK06753 PRK06753
hypothetical protein; Provisional
 97-415 4.15e-20

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 91.67  E-value: 4.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  97 ALACLHR-GIPFTLYEKDNSFSDRAQGYGLtlqqASKAMVGFGINNLEDGVvstkhivhTPDGKIVGEWGMRKWLGNN-S 174
Cdd:PRK06753   15 AAALLQEqGHEVKVFEKNESVKEVGAGIGI----GDNVIKKLGNHDLAKGI--------KNAGQILSTMNLLDDKGTLlN 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 175 KAG--SRRTNIHIARQILRSVLLRPLQNSgSVKWGYELLQFNHCDDHsLNLKFrvnDDVVVEKADLVIGADGIRSIVRRQ 252
Cdd:PRK06753   83 KVKlkSNTLNVTLHRQTLIDIIKSYVKED-AIFTGKEVTKIENETDK-VTIHF---ADGESEAFDLCIGADGIHSKVRQS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 253 ILGEETLplRYLGCMVILGIcrlseIGECDRSLLDSATVFQTANGheRIYIMPYDDVSVMWQLSFPIPQEEAiALRNRGN 332
Cdd:PRK06753  158 VNADSKV--RYQGYTCFRGL-----IDDIDLKLPDCAKEYWGTKG--RFGIVPLLNNQAYWFITINAKERDP-KYSSFGK 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 333 EALKQeaiRRTPWHDPIPQILNasdpsKISGYPVYDRDLLTSELLNT--SGASTLIGDAAHPMSPFKGQGANQALLDALS 410
Cdd:PRK06753  228 PHLQA---YFNHYPNEVREILD-----KQSETGILHHDIYDLKPLKSfvYGRIVLLGDAAHATTPNMGQGAGQAMEDAIV 299


                  ....*
gi 1757094402 411 LAREI 415
Cdd:PRK06753  300 LANCL 304
PRK07538 PRK07538
hypothetical protein; Provisional
 95-415 4.66e-17

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 83.02  E-value: 4.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  95 ALALACLHRGIPFTLYEkdnSFSD-RAQGYGLTLQ-QASKAMVGFGI-NNLEDGVVSTKHIVHtpdgkiVGEWGMRKW-- 169
Cdd:PRK07538   14 TLALTLHQRGIEVVVFE---AAPElRPLGVGINLLpHAVRELAELGLlDALDAIGIRTRELAY------FNRHGQRIWse 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 170 -LGnnSKAGSRRTNIHIARQILRSVLLRPLQN---SGSVKWGYELLQFNHCDDHSLNLKFRVNDDVVVE-KADLVIGADG 244
Cdd:PRK07538   85 pRG--LAAGYDWPQYSIHRGELQMLLLDAVRErlgPDAVRTGHRVVGFEQDADVTVVFLGDRAGGDLVSvRGDVLIGADG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 245 IRSIVRRQILGEETlPLRYLGCMVILGICRLSEIgecdrslLDSATVFQTanGHER----IY-IMPYDDVS----VMWQL 315
Cdd:PRK07538  163 IHSAVRAQLYPDEG-PPRWNGVMMWRGVTEAPPF-------LTGRSMVMA--GHLDgklvVYpISEPVDADgrqlINWVA 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 316 SFPIPQEEAIAlRNRGNEALKQE------AIRRTPWHDpIPQILNASDpsKISGYPVYDRDLLTSEllnTSGASTLIGDA 389
Cdd:PRK07538  233 EVRVDDAGAPR-REDWNRPGDLEdflphfADWRFDWLD-VPALIRAAE--AIYEYPMVDRDPLPRW---TRGRVTLLGDA 305

                         330       340
                  ....*....|....*....|....*.
gi 1757094402 390 AHPMSPFKGQGANQALLDALSLAREI 415
Cdd:PRK07538  306 AHPMYPVGSNGASQAILDARALADAL 331
PRK06847 PRK06847
hypothetical protein; Provisional
 95-458 6.09e-13

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 69.90  E-value: 6.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  95 ALALACLHRGIPFTLYEKDNSFsdRAQGYGLTLQQAS-KAM-----------VGFGInnleDGVVstkhiVHTPDGKIVG 162
Cdd:PRK06847   18 SAAIALRRAGIAVDLVEIDPEW--RVYGAGITLQGNAlRALrelgvldecleAGFGF----DGVD-----LFDPDGTLLA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 163 EwGMRKWLGNNSKAGsrrtNIHIARQILRSVLLRPLQNSG-SVKWGyelLQFNHCDDHSlnlkfrvnDDVVVE------- 234
Cdd:PRK06847   87 E-LPTPRLAGDDLPG----GGGIMRPALARILADAARAAGaDVRLG---TTVTAIEQDD--------DGVTVTfsdgttg 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRQILGEETLPlRYLG-----------------CM-----VILGICRLSEigecdrsllDSATVF 292
Cdd:PRK06847  151 RYDLVVGADGLYSKVRSLVFPDEPEP-EYTGqgvwravlprpaevdrsLMylgptTKAGVVPLSE---------DLMYLF 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 293 QTANGHERIYIMPYDDVSVMWQLSFPIPQEEAIALRnrgnealkqeairrtpwhdpiPQIlnaSDPSKIsgypVYDRdlL 372
Cdd:PRK06847  221 VTEPRPDNPRIEPDTLAALLRELLAPFGGPVLQELR---------------------EQI---TDDAQV----VYRP--L 270

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 373 TSELLNTS---GASTLIGDAAHPMSPFKGQGANQALLDALSLAREITKGcsnpNDWQDKdireiiLNRFEAEMLQRSAIK 449
Cdd:PRK06847  271 ETLLVPAPwhrGRVVLIGDAAHATTPHLAQGAGMAIEDAIVLAEELARH----DSLEAA------LQAYYARRWERCRMV 340


                  ....*....
gi 1757094402 450 VEDSAAAAE 458
Cdd:PRK06847  341 VEASARIGR 349
PRK06185 PRK06185
FAD-dependent oxidoreductase;
235-413 1.24e-09

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 59.87  E-value: 1.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRQiLGeetLPLRYLGCMVILGICRLSEIGEcdrsllDSATVF-QTANGHERIYIMPYDDvsvmW 313
Cdd:PRK06185  157 RADLVVGADGRHSRVRAL-AG---LEVREFGAPMDVLWFRLPREPD------DPESLMgRFGPGQGLIMIDRGDY----W 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 314 QLSFPIPQEEAIALRNRGNEALKQEAIRRTPW-HDPIPQILNASDPS----KISGYPVYDRD-LLtsellntsgastLIG 387
Cdd:PRK06185  223 QCGYVIPKGGYAALRAAGLEAFRERVAELAPElADRVAELKSWDDVKlldvRVDRLRRWHRPgLL------------CIG 290

                         170       180
                  ....*....|....*....|....*.
gi 1757094402 388 DAAHPMSPFKGQGANQALLDALSLAR 413
Cdd:PRK06185  291 DAAHAMSPVGGVGINLAIQDAVAAAN 316
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 203-412 4.96e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 57.72  E-value: 4.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 203 SVKWGYELLQFNHCDDH-SLNLKFRVNDDVVVEKADLVIGADGIRSIVRRQI----LGEETLPLRYLGcmVILGICRLSE 277
Cdd:pfam01494 116 QVRFGTEVLSLEQDGDGvTAVVRDRRDGEEYTVRAKYLVGCDGGRSPVRKTLgiefEGFEGVPFGSLD--VLFDAPDLSD 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 278 IGEcdrsllDSATVFQTANGHERIY-IMPYD---DVSVMWQLSFPIPQEEaialrnRGNEALKQEAIRRTPWHDPIPQIL 353
Cdd:pfam01494 194 PVE------RAFVHYLIYAPHSRGFmVGPWRsagRERYYVQVPWDEEVEE------RPEEFTDEELKQRLRSIVGIDLAL 261

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1757094402 354 naSDPSKISGYPVYDRdlLTSELlnTSGASTLIGDAAHPMSPFKGQGANQALLDALSLA 412
Cdd:pfam01494 262 --VEILWKSIWGVASR--VATRY--RKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLA 314
PRK07236 PRK07236
hypothetical protein; Provisional
 233-460 3.69e-08

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 55.31  E-value: 3.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 233 VEKADLVIGADGIRSIVRRQILGEetLPLRYLGCMVILGICRLSEIGECDRSLLDSATVFQTANGHERI-YIMP------ 305
Cdd:PRK07236  140 RETADLLVGADGGRSTVRAQLLPD--VRPTYAGYVAWRGLVDEAALPPEARAALRDRFTFQLGPGSHILgYPVPgedgst 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 306 -----------YDDVS--------------VMWQLSFP---IPQEEAIALRNRGNEALK---QEAIRRTPwhDPIPQiln 354
Cdd:PRK07236  218 epgkrrynwvwYRNAPageeldelltdrdgTRRPFSVPpgaLRDDVLAELRDDAAELLApvfAELVEATA--QPFVQ--- 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 355 asdpskisgyPVYDrdlLTSELLnTSGASTLIGDAAHPMSPFKGQGANQALLDALSLAREITkgcsnpndwQDKDIREII 434
Cdd:PRK07236  293 ----------AIFD---LEVPRM-AFGRVALLGDAAFVARPHTAAGVAKAAADAVALAEALA---------AAAGDIDAA 349

                         250       260
                  ....*....|....*....|....*.
gi 1757094402 435 LNRFEAEMLQRSAIKVEDSAAAAEYL 460
Cdd:PRK07236  350 LAAWEAERLAVGAAIVARGRRLGARL 375
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 235-441 4.35e-08

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 54.90  E-value: 4.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRQiLGEETLPLRYLGCMVIlgiCRLseigECDRSLLDSATVFQTANGHERIYIMPYDDVSVMWQ 314
Cdd:TIGR01988 151 RARLLVGADGANSKVRQL-AGIPTTGWDYGQSAVV---ANV----KHERPHQGTAWERFTPTGPLALLPLPDNRSSLVWT 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 315 LsfpiPQEEAIALRNRGNEALKQEAIRRTPWHDPIPQILnasdpSKISGYPvydrdlLTSELLNTSGAS--TLIGDAAHP 392
Cdd:TIGR01988 223 L----PPEEAERLLALSDEEFLAELQRAFGSRLGAITLV-----GERHAFP------LSLTHAKRYVAPrlALIGDAAHT 287

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1757094402 393 MSPFKGQGANQALLDALSLAREITKGCSNPNDWQDKDireiILNRFEAE 441
Cdd:TIGR01988 288 IHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLR----VLQRYERR 332
PLN02927 PLN02927
antheraxanthin epoxidase/zeaxanthin epoxidase
 96-415 3.45e-07

antheraxanthin epoxidase/zeaxanthin epoxidase


Pssm-ID: 178515 [Multi-domain]  Cd Length: 668  Bit Score: 52.79  E-value: 3.45e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  96 LALACLHRGIPFTLYEKDNSfSDRAQG-YGLTLQQASKAMVGFGINN-------LEDGVVSTKHIVHTPDGkIVGEWGMR 167
Cdd:PLN02927   96 FALAAKKKGFDVLVFEKDLS-AIRGEGkYRGPIQIQSNALAALEAIDidvaeqvMEAGCITGDRINGLVDG-ISGSWYVK 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 168 kwLGNNSKAGSRRTNIH--IARQILRSVLLRPLqnsgsvkwGYELLQfnhcdDHSLNLKFRVNDD---VVVE-----KAD 237
Cdd:PLN02927  174 --FDTFTPAASRGLPVTrvISRMTLQQILARAV--------GEDVIR-----NESNVVDFEDSGDkvtVVLEngqryEGD 238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 238 LVIGADGIRSIVRRQILGEETLPlrYLGCMVILGICrlseigecDRSLLDSATV-FQTANGHERIYIMPYDDVSVMWQLS 316
Cdd:PLN02927  239 LLVGADGIWSKVRNNLFGRSEAT--YSGYTCYTGIA--------DFIPADIESVgYRVFLGHKQYFVSSDVGGGKMQWYA 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 317 FpipQEEAIALRNRGNEALKQEAIRRTPWHDPIPQILNASDPSKISGYPVYDRdllTSELLNTSGASTLIGDAAHPMSPF 396
Cdd:PLN02927  309 F---HEEPAGGADAPNGMKKRLFEIFDGWCDNVLDLLHATEEDAILRRDIYDR---SPGFTWGKGRVTLLGDSIHAMQPN 382

                         330
                  ....*....|....*....
gi 1757094402 397 KGQGANQALLDALSLAREI 415
Cdd:PLN02927  383 MGQGGCMAIEDSFQLALEL 401
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 235-439 3.53e-07

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 52.14  E-value: 3.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRqILGEETLPLRYLGCMVILGICrlseigeCDRSllDSATVFQTANGHERIYIMPYDD------ 308
Cdd:PRK05714  156 RAPLVVAADGANSAVRR-LAGCATREWDYLHHAIVTSVR-------CSEP--HRATAWQRFTDDGPLAFLPLERdgdehw 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 309 VSVMWQLSfPIPQEEAIALrnrGNEALKQEAIRRTPWHdpIPQILNAsDPSKIsgYPVYDRDL--LTSELLntsgasTLI 386
Cdd:PRK05714  226 CSIVWSTT-PEEAERLMAL---DDDAFCAALERAFEGR--LGEVLSA-DPRLC--VPLRQRHAkrYVEPGL------ALI 290

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1757094402 387 GDAAHPMSPFKGQGANQALLDALSLAREITKGCSNPNDWQDkdirEIILNRFE 439
Cdd:PRK05714  291 GDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLAD----VRVLSRFE 339
PRK07045 PRK07045
putative monooxygenase; Reviewed
 172-466 5.59e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 51.83  E-value: 5.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 172 NNSKAGSRRTNIHIARQILRSVLLRPLQNSGSVKWGYE--LLQFNHCDDHSLNlKFRVNDDVVVeKADLVIGADGIRSIV 249
Cdd:PRK07045   90 DYRSASALGYFILIPCEQLRRLLLAKLDGLPNVRLRFEtsIERIERDADGTVT-SVTLSDGERV-APTVLVGADGARSMI 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 250 RRQILGEETLPLRYLGCMVILGICRLSEIGECDRSLLDSATVFQtangheriYIMPYDDVSVMWQLSFPIPQEEAI---- 325
Cdd:PRK07045  168 RDDVLRMPAERVPYATPMAFGTIALTDSVRECNRLYVDSNQGLA--------YFYPIGDQATRLVVSFPADEMQGYladt 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 326 ---ALRNRGNEALKQEAIrrtpwhDPIPQILNASDPSKIS-GYPVYDRdlltsellNTSGASTLIGDAAHPMSPFKGQGA 401
Cdd:PRK07045  240 trtKLLARLNEFVGDESA------DAMAAIGAGTAFPLIPlGRMNLDR--------YHKRNVVLLGDAAHSIHPITGQGM 305

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1757094402 402 NQALLDALSLAREITKGCSNPNDWQDKdireiiLNRFEAEMLQRSAIKVEDSAAAAEYLHSELAL 466
Cdd:PRK07045  306 NLAIEDAGELGACLDLHLSGQIALADA------LERFERIRRPVNEAVISYGHALATTYHDRAAL 364
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
379-427 3.17e-06

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 49.27  E-value: 3.17e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1757094402 379 TSGASTLIGDAAHPMSPFKGQGANQALLDALSLArEITKGCsnPNDWQD 427
Cdd:PRK08163  284 STGRVTLLGDAAHPMTQYMAQGACMALEDAVTLG-KALEGC--DGDAEA 329
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
203-412 8.15e-06

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 48.36  E-value: 8.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 203 SVKWGYELLQFNHCDDHsLNLKFRVNDDVVVE-KADLVIGADGIRSIVRRQI---LGEETLPLRYLGCMVilgicrlsei 278
Cdd:PRK06183  130 RVRFGHEVTALTQDDDG-VTVTLTDADGQRETvRARYVVGCDGANSFVRRTLgvpFEDLTFPERWLVVDV---------- 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 279 gECDRSLLDSATVFQTAN------------GHER--IYIMP------YDDVSVMWQLsfpipqeeaIALRNRGNEALkqE 338
Cdd:PRK06183  199 -LIANDPLGGPHTYQYCDparpytsvrlphGRRRweFMLLPgeteeqLASPENVWRL---------LAPWGPTPDDA--E 266

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1757094402 339 AIR-RTPWHDpipqilnasdpSKISGYPVYDRDLLtsellntsgastlIGDAAHPMSPFKGQGANQALLDALSLA 412
Cdd:PRK06183  267 LIRhAVYTFH-----------ARVADRWRSGRVLL-------------AGDAAHLMPPFAGQGMNSGIRDAANLA 317
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 385-415 8.32e-06

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 47.84  E-value: 8.32e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1757094402 385 LIGDAAHPMSPFKGQGANQALLDALSLAREI 415
Cdd:PRK08850  286 LVGDAAHTIHPLAGQGVNLGLLDAASLAQEI 316
PRK06475 PRK06475
FAD-binding protein;
94-412 9.38e-06

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 47.90  E-value: 9.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402  94 TALALAclHRGIPFTLYEKDNSFSDRAQGYGLTlQQASKAMVGFGINNLEDGVVSTKHIVHTPDGkIVGEWGMRKWLGNN 173
Cdd:PRK06475   17 AALELA--ARGWAVTIIEKAQELSEVGAGLQLA-PNAMRHLERLGVADRLSGTGVTPKALYLMDG-RKARPLLAMQLGDL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 174 SKAGSRRTNIHIARQILRSVLLRPLQNSGSVKW--GYELLQFNHcDDHSLNLKFRVNDDVVVEKADLVIGADGIRSIVR- 250
Cdd:PRK06475   93 ARKRWHHPYIVCHRADLQSALLDACRNNPGIEIklGAEMTSQRQ-TGNSITATIIRTNSVETVSAAYLIACDGVWSMLRa 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 251 ---------------RQILGEETLPLRYLGCMvilgicrlseigecdrSLLDSATVFQTANGHERIYimPYDDVSVMWQL 315
Cdd:PRK06475  172 kagfskarfsghiawRTTLAADALPASFLSAM----------------PEHKAVSAWLGNKAHFIAY--PVKGGKFFNFV 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 316 SFPIPQEEAIALRNRGNEAlKQEAIRRTpWHDPIPQILNASDpsKISGYPVY---DRDLLTSEllntsgASTLIGDAAHP 392
Cdd:PRK06475  234 AITGGENPGEVWSKTGDKA-HLKSIYAD-WNKPVLQILAAID--EWTYWPLFemaDAQFVGPD------RTIFLGDASHA 303

                         330       340
                  ....*....|....*....|
gi 1757094402 393 MSPFKGQGANQALLDALSLA 412
Cdd:PRK06475  304 VTPFAAQGAAMAIEDAAALA 323
PRK07588 PRK07588
FAD-binding domain;
237-440 2.10e-05

FAD-binding domain;


Pssm-ID: 169028 [Multi-domain]  Cd Length: 391  Bit Score: 46.65  E-value: 2.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 237 DLVIGADGIRSIVRRQILGEETLPLRYLGCMVilgicrlseigecdrslldSATVFQTANgheriyimPYDDVSVMwqlS 316
Cdd:PRK07588  148 DLVIGADGLHSHVRRLVFGPERDFEHYLGCKV-------------------AACVVDGYR--------PRDERTYV---L 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 317 FPIPQEEAIALRNRGNEAL------------------KQEAIRRT----PWHDpiPQILNASDPSKiSGYpvYDRdllTS 374
Cdd:PRK07588  198 YNEVGRQVARVALRGDRTLflfifraehdnppltpaeEKQLLRDQfgdvGWET--PDILAALDDVE-DLY--FDV---VS 269

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1757094402 375 ELLN---TSGASTLIGDAAHPMSPFKGQGANQALLDALSLAREITKGCSNPND----WQDKdIREIILNRFEA 440
Cdd:PRK07588  270 QIRMdrwSRGRVALVGDAAACPSLLGGEGSGLAITEAYVLAGELARAGGDHRRafdaYEKR-LRPFIAGKQAA 341
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 235-441 2.94e-05

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 46.29  E-value: 2.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRrQILGEETLPLRYLGcMVILGICRLSEIGECDRSlldsatvFQ--TANGHERIYIMPYDDVSVM 312
Cdd:TIGR01989 171 YTKLLIGADGSNSNVR-KAANIDTTGWNYNQ-HAVVATLKLEEATENDVA-------WQrfLPTGPIALLPLPDNNSTLV 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 313 WQLS-------FPIPQEEAIALRNrgnEALKQE--AIRRTPWHDPIPQILNASDPSKISG------YP-----VYDRDLL 372
Cdd:TIGR01989 242 WSTSpeealrlLSLPPEDFVDALN---AAFDLGysDHPYSYLLDYAMEKLNEDIGFRTEGskscfqVPprvigVVDKSRA 318

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1757094402 373 TSELLNTSGAS------TLIGDAAHPMSPFKGQGANQALLDALSLAREITKGCSNPNDWQDKdireIILNRFEAE 441
Cdd:TIGR01989 319 AFPLGLGHADEyvtkrvALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSI----SSLKPYERE 389
PRK06126 PRK06126
hypothetical protein; Provisional
 183-480 5.71e-05

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 45.75  E-value: 5.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 183 IHIARQI-LRSVLLRPLQNSGSVK--WGYELLQFNHCDDHSlnlkfrvndDVVVE----------KADLVIGADGIRSIV 249
Cdd:PRK06126  120 PHRIPQKyLEPILLEHAAAQPGVTlrYGHRLTDFEQDADGV---------TATVEdldggesltiRADYLVGCDGARSAV 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 250 RRQI---LGEETLPLRYLGcmVILGICRLSEIGECDRSLL------DSATVFQTANGHER---IYIMPYDDvsvmwqlSF 317
Cdd:PRK06126  191 RRSLgisYEGTSGLQRDLS--IYIRAPGLAALVGHDPAWMywlfnpDRRGVLVAIDGRDEwlfHQLRGGED-------EF 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 318 PIPQEEAIALRNRG-NEALKQEAIRRTPWHDpipqilnasdpskisgypvydRDLLTSELlnTSGASTLIGDAAHPMSPF 396
Cdd:PRK06126  262 TIDDVDARAFVRRGvGEDIDYEVLSVVPWTG---------------------RRLVADSY--RRGRVFLAGDAAHLFTPT 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 397 KGQGANQALLDALSLAREITkgcSNPNDWQDKDireiILNRFEAEmlqRSAIKVEDSAAAAEYLHSeLALF------EAD 470
Cdd:PRK06126  319 GGYGMNTGIGDAVNLAWKLA---AVLNGWAGPA----LLDSYEAE---RRPIAARNTDYARRNADA-LGSFpvppeiEDD 387

                         330
                  ....*....|
gi 1757094402 471 EPRGKVIKRK 480
Cdd:PRK06126  388 GPAGDAARRK 397
PRK07364 PRK07364
FAD-dependent hydroxylase;
192-439 7.04e-05

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 45.01  E-value: 7.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 192 SVLLRPLQNS----GSVKWGY--ELLQfNHCDDHSLNLKFRVNDDVVVEKADLVIGADGIRSIVRrQILGEETLPLRYL- 264
Cdd:PRK07364  121 QVLLEALQEFlqscPNITWLCpaEVVS-VEYQQDAATVTLEIEGKQQTLQSKLVVAADGARSPIR-QAAGIKTKGWKYWq 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 265 GCMVilgicrlseigecdrslldsATV----FQTANGHER--------IYIMPYDDVSVMWQLsfpiPQEEAIALRNRGN 332
Cdd:PRK07364  199 SCVT--------------------ATVkheaPHNDIAYERfwpsgpfaILPLPGNRCQIVWTA----PHAQAKALLALPE 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 333 EALKQEAIRRTPwhDPIPQILNASDPSKisgYPV-------YDRDLLTsellntsgastLIGDAAHPMSPFKGQGANQAL 405
Cdd:PRK07364  255 AEFLAELQQRYG--DQLGKLELLGDRFL---FPVqlmqsdrYVQHRLA-----------LVGDAAHCCHPVGGQGLNLGI 318

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1757094402 406 LDALSLAREITKgcsnpnDWQ-DKDIREI-ILNRFE 439
Cdd:PRK07364  319 RDAAALAQVLQT------AHQrGEDIGSLaVLKRYE 348
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
235-439 8.91e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 44.56  E-value: 8.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 235 KADLVIGADGIRSIVRRQI-LGEETLPLRYLGCMVILgicrlseigECDRSLLDSAtvFQTANGHERIYIMPYDD--VSV 311
Cdd:PRK07608  155 RADLVVGADGAHSWVRSQAgIKAERRPYRQTGVVANF---------KAERPHRGTA--YQWFRDDGILALLPLPDghVSM 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757094402 312 MWQLSFPIPQE------EAIALR--NRGNEALKQEAIRrTPWHdpipqilnasdpskisGYPVydrDLLTSELLNTSGAS 383
Cdd:PRK07608  224 VWSARTAHADEllalspEALAARveRASGGRLGRLECV-TPAA----------------GFPL---RLQRVDRLVAPRVA 283

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1757094402 384 tLIGDAAHPMSPFKGQGANQALLDALSLAREI--TKGCSNPNDWQdkdireiILNRFE 439
Cdd:PRK07608  284 -LVGDAAHLIHPLAGQGMNLGLRDVAALADVLagREPFRDLGDLR-------LLRRYE 333
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 385-414 7.91e-04

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 41.51  E-value: 7.91e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1757094402 385 LIGDAAHPMSPFKGQGAN------QALLDALSLARE 414
Cdd:PRK08020  285 LVGDAAHTINPLAGQGVNlgyrdvDALLDVLVNARS 320
PRK08013 PRK08013
oxidoreductase; Provisional
 385-439 1.24e-03

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 41.18  E-value: 1.24e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1757094402 385 LIGDAAHPMSPFKGQGANQALLDALSLAREITKGCSnpndwQDKDIRE-IILNRFE 439
Cdd:PRK08013  286 LVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHR-----QGKDIGQhLYLRRYE 336
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 385-424 2.30e-03

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 40.22  E-value: 2.30e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1757094402 385 LIGDAAHPMSPFKGQGANQALLDALSLAREITKGCSNPND 424
Cdd:PRK05732  286 LVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGED 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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