NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1721669871|gb|QEC73827|]
View 

SusC/RagA family TonB-linked outer membrane protein [Arachidicoccus ginsenosidivorans]

Protein Classification

SusC/RagA family TonB-linked outer membrane protein( domain architecture ID 1000763)

SusC/RagA family TonB-linked outer membrane protein

Gene Ontology:  GO:0022857|GO:0009279

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OMP_RagA_SusC super family cl37378
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 31-945 6.47e-133

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


The actual alignment was detected with superfamily member TIGR04056:

Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 425.47  E-value: 6.47e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  31 RTVSGQITDSLGTGLPGVTVSVNDPKGNVISGTDGHYQIKAKDGTTLTFMYVGYETKTVIVN-QDEINVSLSAQTNEAGt 109
Cdd:TIGR04056   1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKgQKNLNITLKEDTQELD- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 110 DVVVTAFGmKRSERSLGYAATTVKSDDITRTGTTNFATALYGKVPGLQIQAAPGGSTSGVYMQLRGVNSMLGKTTPLIIM 189
Cdd:TIGR04056  80 EVVVVGYG-TQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 190 DGVPirdgafnsgnywgdqreRNNGIVDINPEDIENITVLKGAAAAALYGSEGVNGVVMITTKSGKNNKkgFSVDVNANY 269
Cdd:TIGR04056 159 DGVP-----------------RDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGK--PKISYNAEF 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 270 FQDQVAYLPRFQNTRgtgfpsqvpgyytsdangfntqQYADAngnMYRALVQGNLNFGPVFDGKPIIAWDGVVRPY-SAQ 348
Cdd:TIGR04056 220 GFSTPTRLPEMLNAY----------------------EYAEL---YNEALLNRGSSPPDIYTDEEIEAYRNGLDPDlYPN 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 349 PDRYKNLFQK-ANNSTQTVAISSNSAVQSTRFSVTNQHTEGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHN 427
Cdd:TIGR04056 275 TDWQDEIFKRtAFNQRHNLSVSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNN 354

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 428 RPYLIDRMIN---NFTGMMPVfdngdWYRNKYQTSLGYKYVLNTTQSLTPdenihipsymtdildyMWNVNKDIYDEYEN 504
Cdd:TIGR04056 355 PGGSTSNIWGalmLFPRGTPY-----STPPVYSDGYYPAYNSGNTSLQNP----------------YALLNRGYNENERN 413

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 505 RLIASITDSWTITKGLKLRGRVSTDYTN---TNIYDKQSSTQPIVYGASGNYGVQNVYYNMLHADVMMEYNTKLSpDFDL 581
Cdd:TIGR04056 414 RLNGNASLEQKITKGLKLKGTFSYDYSNyknKKYYKNPYYYNATGGANNGYYSESNSRSRNYYLEATLNYNRTFG-KHNV 492

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 582 TATAFYTADKEKGQNTSiYTNGGLSSENWFDLAATANPISNPSAppleivKDAIIGTVNINYHNYLYAEGTIRRDRTSTM 661
Cdd:TIGR04056 493 SALLGYSQQENKSSSYG-GLLDDLPSLDAGTSDASVSGSDSEYR------LQSLFGRATYSYKDRYLLEFNFRYDGSSRF 565

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 662 NPDNNSFVYPSANAGFIISD-AF--KLPETINYLKLRASWGIVGNY--PDPYKANVAYLPANWGTQAPGTSPVLTTNTNF 736
Cdd:TIGR04056 566 AKGNRWGFFPSVSLGWRISEeKFmkKLKKWLSFLKLRASYGIVGNDniGDRYPYLSLYNLGDGGYNFGTNNGTSVTGITE 645

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 737 NIYGNLNIRPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPID 816
Cdd:TIGR04056 646 SRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKI 725

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 817 LKDFKWSFILNYANYSNKVVAISENSNSIIYGDYdgnayqiVARVGHPAGEI---MAHPLLKDD------KGNLIVDDag 887
Cdd:TIGR04056 726 GKDFSWSVRGNFTYNKNKILELDEGAYLPVKYPY-------ISKEGGPIGQIygyIADGLFKDDdspkqtFGNVRPGD-- 796

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1721669871 888 LYEQDPN---KMESY------GSIQSKGYGGFINTFTYKNFQLNFSIDYRYGGHVIPTGIFWMNSRG 945
Cdd:TIGR04056 797 IKYKDVNgdgKIDDDdrvpigYSNTPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNG 863
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 31-945 6.47e-133

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 425.47  E-value: 6.47e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  31 RTVSGQITDSLGTGLPGVTVSVNDPKGNVISGTDGHYQIKAKDGTTLTFMYVGYETKTVIVN-QDEINVSLSAQTNEAGt 109
Cdd:TIGR04056   1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKgQKNLNITLKEDTQELD- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 110 DVVVTAFGmKRSERSLGYAATTVKSDDITRTGTTNFATALYGKVPGLQIQAAPGGSTSGVYMQLRGVNSMLGKTTPLIIM 189
Cdd:TIGR04056  80 EVVVVGYG-TQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 190 DGVPirdgafnsgnywgdqreRNNGIVDINPEDIENITVLKGAAAAALYGSEGVNGVVMITTKSGKNNKkgFSVDVNANY 269
Cdd:TIGR04056 159 DGVP-----------------RDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGK--PKISYNAEF 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 270 FQDQVAYLPRFQNTRgtgfpsqvpgyytsdangfntqQYADAngnMYRALVQGNLNFGPVFDGKPIIAWDGVVRPY-SAQ 348
Cdd:TIGR04056 220 GFSTPTRLPEMLNAY----------------------EYAEL---YNEALLNRGSSPPDIYTDEEIEAYRNGLDPDlYPN 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 349 PDRYKNLFQK-ANNSTQTVAISSNSAVQSTRFSVTNQHTEGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHN 427
Cdd:TIGR04056 275 TDWQDEIFKRtAFNQRHNLSVSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNN 354

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 428 RPYLIDRMIN---NFTGMMPVfdngdWYRNKYQTSLGYKYVLNTTQSLTPdenihipsymtdildyMWNVNKDIYDEYEN 504
Cdd:TIGR04056 355 PGGSTSNIWGalmLFPRGTPY-----STPPVYSDGYYPAYNSGNTSLQNP----------------YALLNRGYNENERN 413

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 505 RLIASITDSWTITKGLKLRGRVSTDYTN---TNIYDKQSSTQPIVYGASGNYGVQNVYYNMLHADVMMEYNTKLSpDFDL 581
Cdd:TIGR04056 414 RLNGNASLEQKITKGLKLKGTFSYDYSNyknKKYYKNPYYYNATGGANNGYYSESNSRSRNYYLEATLNYNRTFG-KHNV 492

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 582 TATAFYTADKEKGQNTSiYTNGGLSSENWFDLAATANPISNPSAppleivKDAIIGTVNINYHNYLYAEGTIRRDRTSTM 661
Cdd:TIGR04056 493 SALLGYSQQENKSSSYG-GLLDDLPSLDAGTSDASVSGSDSEYR------LQSLFGRATYSYKDRYLLEFNFRYDGSSRF 565

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 662 NPDNNSFVYPSANAGFIISD-AF--KLPETINYLKLRASWGIVGNY--PDPYKANVAYLPANWGTQAPGTSPVLTTNTNF 736
Cdd:TIGR04056 566 AKGNRWGFFPSVSLGWRISEeKFmkKLKKWLSFLKLRASYGIVGNDniGDRYPYLSLYNLGDGGYNFGTNNGTSVTGITE 645

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 737 NIYGNLNIRPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPID 816
Cdd:TIGR04056 646 SRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKI 725

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 817 LKDFKWSFILNYANYSNKVVAISENSNSIIYGDYdgnayqiVARVGHPAGEI---MAHPLLKDD------KGNLIVDDag 887
Cdd:TIGR04056 726 GKDFSWSVRGNFTYNKNKILELDEGAYLPVKYPY-------ISKEGGPIGQIygyIADGLFKDDdspkqtFGNVRPGD-- 796

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1721669871 888 LYEQDPN---KMESY------GSIQSKGYGGFINTFTYKNFQLNFSIDYRYGGHVIPTGIFWMNSRG 945
Cdd:TIGR04056 797 IKYKDVNgdgKIDDDdrvpigYSNTPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNG 863
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
111-829 2.07e-34

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 140.73  E-value: 2.07e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSgvyMQLRGVNSmlGKTTPLIIMD 190
Cdd:COG1629     4 VVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAGGGAGQ---ISIRGFGG--GGNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVPIrdgafnsgnywGDQRERNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNnkkGFSVDVNANYf 270
Cdd:COG1629    78 GVPL-----------NDPSGGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKD---GKGGEVSASY- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 271 qdqvaylprfqntrgtgfpsqvpgyytsdaNGFNTQQYadangnmyralvqgnlnfgpvfdgkpiiawdgvvrpysaqpd 350
Cdd:COG1629   142 ------------------------------GSYGTYRA------------------------------------------ 149

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 351 ryknlfqkannstqTVAISSNSAVQSTRFSVTNQHTEGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHNRPY 430
Cdd:COG1629   150 --------------SLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGY 215

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 431 LIDRMINNFTGMMPVFDNGDWYRNKYQTSLGYkyvlnttqsltpdenihipsymtdiLDYMWNvnkdiydeyenrliasi 510
Cdd:COG1629   216 LTLAALRPRGAMDDGTNPYSNDTDDNTRDRYS-------------------------LSLEYE----------------- 253

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 511 tdswTITKGLKLRGRVSTDYTNTNIYDKQSSTqpivYGASGNYGVQNVYYNMLHADVMMEYNTKLSPDFDLTATAFYTAD 590
Cdd:COG1629   254 ----HLGDGLKLSASAYYRYDDTDLDSDFTPT----PADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQ 325

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 591 KEKGQNTSIYTNGGLSsenwfdlaataNPISNPSAPPLEIVKDAIIGTVNINYHNYLYAEGTIRRDRTSTmnpDNNSFVY 670
Cdd:COG1629   326 DLDGSGYPLDLGSGSL-----------PTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSY---DVDDTVT 391

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 671 PSANAGFIISDAFKLPE-TINY-----LKLRASWGIvgnypdpykanvaylpanwGTQAPGTSPVLTTNTNFNIYGNLNI 744
Cdd:COG1629   392 GTDSASGSRSYSAFSPSlGLTYqlspnLSLYASYSR-------------------GFRAPTFGELYANGTDPYSVGNPDL 452

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 745 RPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPIDlkdfKWSF 824
Cdd:COG1629   453 KPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSL 528


                  ....*
gi 1721669871 825 ILNYA 829
Cdd:COG1629   529 NASYS 533
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 123-246 4.22e-18

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 80.78  E-value: 4.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 123 RSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSGVYMqlRGVNSmlgkTTPLIIMDGVPIRDGAFNSG 202
Cdd:pfam07715   3 RDTPGSVSVVTAEDIEDQGATNLADAL-RGVPGVSVSSGGGGGGSSISI--RGFGS----NRVLVLVDGVPLNSGGGGSV 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1721669871 203 NYWgdqrernngivDINPEDIENITVLKGaAAAALYGSEGVNGV 246
Cdd:pfam07715  76 DLN-----------SIDPEDIERVEVLKG-PASALYGSGAIGGV 107
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 130-829 3.21e-11

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 67.09  E-value: 3.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 130 TTVKSDDITRTGTTNFATALYgKVPGLQIQAAPGGSTSGVYmqLRGvnsmLGKTTPLIIMDGVPIrdgafNSGNYWgdqr 209
Cdd:cd01347     3 SVITAEDIEKQPATSLADLLR-RIPGVSVTRGGGGGGSTIS--IRG----FGPDRTLVLVDGLPL-----ASSNYG---- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 210 eRNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNnkkGFSVDVNANYFQDQVAylprfqNTRGTGFp 289
Cdd:cd01347    67 -RGVDLNTIPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTD---EFGGSVTAGYGSDNSG------SSGGGGF- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 290 sqvpgyYTSDANGFNTQQYADANGNMYRALVQGNLNFGPVFDGKPIIAWDGVVrpySAQPDRyknlfqkannstqtvais 369
Cdd:cd01347   135 ------DVSGALADDGAFGARLYGAYRDGDGTIDGDGQADDSDEERYNVAGKL---DWRPDD------------------ 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 370 snsavqSTRFSVTNQHTEGlsigsKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHNRPYLIDRMINNFTgmmpvfDNG 449
Cdd:cd01347   188 ------DTRLTLDAGYQDQ-----DADGPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLE------HDL 250

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 450 DWYRNKYQTSLGYKYVLNTTQSLTpdenihipsymtdilDYMWNVNKDIYDEYENRLIASITDSWTITKGLKLRgrvstd 529
Cdd:cd01347   251 NDTGWTLRANLSYSYTDNDGDPLI---------------LNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAP------ 309

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 530 ytntniYDKQSSTQPIVYGASGNYGVQNVYynmLHAdVMMEYNTKLSPDFDLTATAFYtadkekgQNTSIYTNGGlssen 609
Cdd:cd01347   310 ------FGTGPVAHTLTLGVEYRREELDEK---QTA-LYAQDTIELTDDLTLTLGLRY-------DHYDQDSKDT----- 367

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 610 wfdlaatanpisnpsappleivkDAIIGTVNINYHNYLyaegtirrdrtstmnpdnnsfvyPSANAGFIISDafklpeti 689
Cdd:cd01347   368 -----------------------IAGGTTAKKSYSHWS-----------------------PSLGLVYKLTD-------- 393

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 690 nYLKLRASWGIVGNYPDPYKANVAYLPanwgtqapgtspvlttnTNFNIYGNLNIRPEKKNEYEFGLTGQlLHSRLGFDA 769
Cdd:cd01347   394 -GLSLYASYSQGFRAPSLGELYGGGSH-----------------GGTAAVGNPNLKPEKSKQYELGLKYD-PGDGLTLSA 454

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 770 TFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPIDlkdfKWSFILNYA 829
Cdd:cd01347   455 ALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTD----GLGLTGSYT 510
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 102-260 8.20e-08

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 56.30  E-value: 8.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 102 AQTNEAGTDVVVTAFGMKRSERSLGYAATTvkSDDITRTGTTNFATALYGKVPGLQIQaapGGSTSGVY-----MQLRGv 176
Cdd:PRK13528   28 SSDDDNGETMVVEATAEQELKQQPGVSIIT--AEDIKKRPPVNDLSDIIRKMPGVNLT---GNSASGTRgnnrqIDIRG- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 177 nsmLGKTTPLIIMDGVPIRdgAFNSGNY-W-GDQRERNngivDIN---PEDIENITVLKGAAAAAlYGSEGVNGVVMITT 251
Cdd:PRK13528  102 ---MGPENTLILIDGVPVT--SRNSVRYsWrGERDTRG----DTNwvpPEMVERIEVIRGPAAAR-YGSGAAGGVVNIIT 171


                  ....*....
gi 1721669871 252 KSGKNNKKG 260
Cdd:PRK13528  172 KRPTNDWHG 180
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 31-945 6.47e-133

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 425.47  E-value: 6.47e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  31 RTVSGQITDSLGTGLPGVTVSVNDPKGNVISGTDGHYQIKAKDGTTLTFMYVGYETKTVIVN-QDEINVSLSAQTNEAGt 109
Cdd:TIGR04056   1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKgQKNLNITLKEDTQELD- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 110 DVVVTAFGmKRSERSLGYAATTVKSDDITRTGTTNFATALYGKVPGLQIQAAPGGSTSGVYMQLRGVNSMLGKTTPLIIM 189
Cdd:TIGR04056  80 EVVVVGYG-TQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 190 DGVPirdgafnsgnywgdqreRNNGIVDINPEDIENITVLKGAAAAALYGSEGVNGVVMITTKSGKNNKkgFSVDVNANY 269
Cdd:TIGR04056 159 DGVP-----------------RDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGK--PKISYNAEF 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 270 FQDQVAYLPRFQNTRgtgfpsqvpgyytsdangfntqQYADAngnMYRALVQGNLNFGPVFDGKPIIAWDGVVRPY-SAQ 348
Cdd:TIGR04056 220 GFSTPTRLPEMLNAY----------------------EYAEL---YNEALLNRGSSPPDIYTDEEIEAYRNGLDPDlYPN 274

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 349 PDRYKNLFQK-ANNSTQTVAISSNSAVQSTRFSVTNQHTEGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHN 427
Cdd:TIGR04056 275 TDWQDEIFKRtAFNQRHNLSVSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNN 354

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 428 RPYLIDRMIN---NFTGMMPVfdngdWYRNKYQTSLGYKYVLNTTQSLTPdenihipsymtdildyMWNVNKDIYDEYEN 504
Cdd:TIGR04056 355 PGGSTSNIWGalmLFPRGTPY-----STPPVYSDGYYPAYNSGNTSLQNP----------------YALLNRGYNENERN 413

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 505 RLIASITDSWTITKGLKLRGRVSTDYTN---TNIYDKQSSTQPIVYGASGNYGVQNVYYNMLHADVMMEYNTKLSpDFDL 581
Cdd:TIGR04056 414 RLNGNASLEQKITKGLKLKGTFSYDYSNyknKKYYKNPYYYNATGGANNGYYSESNSRSRNYYLEATLNYNRTFG-KHNV 492

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 582 TATAFYTADKEKGQNTSiYTNGGLSSENWFDLAATANPISNPSAppleivKDAIIGTVNINYHNYLYAEGTIRRDRTSTM 661
Cdd:TIGR04056 493 SALLGYSQQENKSSSYG-GLLDDLPSLDAGTSDASVSGSDSEYR------LQSLFGRATYSYKDRYLLEFNFRYDGSSRF 565

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 662 NPDNNSFVYPSANAGFIISD-AF--KLPETINYLKLRASWGIVGNY--PDPYKANVAYLPANWGTQAPGTSPVLTTNTNF 736
Cdd:TIGR04056 566 AKGNRWGFFPSVSLGWRISEeKFmkKLKKWLSFLKLRASYGIVGNDniGDRYPYLSLYNLGDGGYNFGTNNGTSVTGITE 645

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 737 NIYGNLNIRPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPID 816
Cdd:TIGR04056 646 SRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKI 725

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 817 LKDFKWSFILNYANYSNKVVAISENSNSIIYGDYdgnayqiVARVGHPAGEI---MAHPLLKDD------KGNLIVDDag 887
Cdd:TIGR04056 726 GKDFSWSVRGNFTYNKNKILELDEGAYLPVKYPY-------ISKEGGPIGQIygyIADGLFKDDdspkqtFGNVRPGD-- 796

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1721669871 888 LYEQDPN---KMESY------GSIQSKGYGGFINTFTYKNFQLNFSIDYRYGGHVIPTGIFWMNSRG 945
Cdd:TIGR04056 797 IKYKDVNgdgKIDDDdrvpigYSNTPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNG 863
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
111-829 2.07e-34

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 140.73  E-value: 2.07e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSgvyMQLRGVNSmlGKTTPLIIMD 190
Cdd:COG1629     4 VVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAGGGAGQ---ISIRGFGG--GGNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVPIrdgafnsgnywGDQRERNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNnkkGFSVDVNANYf 270
Cdd:COG1629    78 GVPL-----------NDPSGGDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKD---GKGGEVSASY- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 271 qdqvaylprfqntrgtgfpsqvpgyytsdaNGFNTQQYadangnmyralvqgnlnfgpvfdgkpiiawdgvvrpysaqpd 350
Cdd:COG1629   142 ------------------------------GSYGTYRA------------------------------------------ 149

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 351 ryknlfqkannstqTVAISSNSAVQSTRFSVTNQHTEGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHNRPY 430
Cdd:COG1629   150 --------------SLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGY 215

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 431 LIDRMINNFTGMMPVFDNGDWYRNKYQTSLGYkyvlnttqsltpdenihipsymtdiLDYMWNvnkdiydeyenrliasi 510
Cdd:COG1629   216 LTLAALRPRGAMDDGTNPYSNDTDDNTRDRYS-------------------------LSLEYE----------------- 253

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 511 tdswTITKGLKLRGRVSTDYTNTNIYDKQSSTqpivYGASGNYGVQNVYYNMLHADVMMEYNTKLSPDFDLTATAFYTAD 590
Cdd:COG1629   254 ----HLGDGLKLSASAYYRYDDTDLDSDFTPT----PADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQ 325

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 591 KEKGQNTSIYTNGGLSsenwfdlaataNPISNPSAPPLEIVKDAIIGTVNINYHNYLYAEGTIRRDRTSTmnpDNNSFVY 670
Cdd:COG1629   326 DLDGSGYPLDLGSGSL-----------PTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSY---DVDDTVT 391

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 671 PSANAGFIISDAFKLPE-TINY-----LKLRASWGIvgnypdpykanvaylpanwGTQAPGTSPVLTTNTNFNIYGNLNI 744
Cdd:COG1629   392 GTDSASGSRSYSAFSPSlGLTYqlspnLSLYASYSR-------------------GFRAPTFGELYANGTDPYSVGNPDL 452

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 745 RPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPIDlkdfKWSF 824
Cdd:COG1629   453 KPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSL 528


                  ....*
gi 1721669871 825 ILNYA 829
Cdd:COG1629   529 NASYS 533
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 111-829 4.74e-32

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 133.06  E-value: 4.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAApGGSTSGVYMQLRGVNSmlgkTTPLIIMD 190
Cdd:COG4771    30 VVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADAL-RLLPGVSVTRS-GGRGGSSGISIRGLGG----DRVLVLID 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVPIRDGAFNSGNYWGDqrernngivdINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNNKKGfSVDVNANYF 270
Cdd:COG4771   104 GVPVNNPALGGGGDLSY----------IPPDDIERIEVIRGPASA-LYGSDAIGGVINIITKKPTDELEG-SVSLGYGSN 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 271 QDQvaylpRFQNTRGTGFPSQVPGYYTSdANGFNTQQYADANGNmyralvqgnlnfgpvfdgkpiiawdgvvrpysaqpd 350
Cdd:COG4771   172 GNG-----TYSGSLSLGGPGDKLSFLLS-GSYRDRDGYLDYRNG------------------------------------ 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 351 ryknlfqkannstqtvaissnsavqstrfsvtnqhteGLSIGSKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHNRPY 430
Cdd:COG4771   210 -------------------------------------GFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPP 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 431 LIDRMINNFTGMmpvfDNGDWYRNKYQTSLGYKYVLNTtqsltpdenihipsymtdildymwnvnkdiydeyenrliasi 510
Cdd:COG4771   253 TLGDTEISSDNA----GDRDTTTDRGNYSLRYNGDLGD------------------------------------------ 286

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 511 tdswtitkglKLRGRVSTDYTNTNiydkqsSTQPIVYGASGNYGVQNVYYNMLHADvmmeYNTKLSPDFDLTATAFYTad 590
Cdd:COG4771   287 ----------NLDLSLYYSRTDRD------STNGSLGGSTGSFSDSDDTTYGLELD----LTYPLGGNHTLTLGAEYR-- 344

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 591 KEKGQNTSIYTNGGLSSENWfdlaatanpisnpsappleivkdAIIGTVNINYHNYLYAEGTIRRDRTSTMNPDNNSFVY 670
Cdd:COG4771   345 YDDLDSSSFLGGADASRDTY-----------------------GLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFS 401

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 671 PSANAGFIISDAfklpetinyLKLRASWGIVGNYPDPYKANVAYLPanwgtqapgtspvlttNTNFNIYGNLNIRPEKKN 750
Cdd:COG4771   402 PRLGLRYDLSDN---------LTLRASYGRGFRAPSLAELYGSGTG----------------TPGRYVLGNPDLKPETSD 456

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1721669871 751 EYEFGLTGQLLHSRLGFDATFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPIDlkdfKWSFILNYA 829
Cdd:COG4771   457 NYELGLEYRLGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQYENVGKARTYGLELELKYRLGK----GLTLTASYT 531
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
111-314 7.97e-31

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 122.67  E-value: 7.97e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAApGGSTSGVYMQLRGVNSmlgkTTPLIIMD 190
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADAL-RRVPGVQVSSS-GGPGSAASISIRGLGS----NQTLVLID 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVPIRDGAFNSgnywgdqrernNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNNKKGfSVDVNANYF 270
Cdd:COG4206    75 GVPLNDPSLGG-----------VDLSLIPPDDIERIEVLKGAASA-LYGSDAIGGVINITTKKGKKGFKG-SVSASYGSF 141

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1721669871 271 QdqvaylprFQNTRGTGFPSQVPGYYTSDANGFNTQQYADANGN 314
Cdd:COG4206   142 G--------TRRLSASLSGGAGKFSYSLSASYRRSDGYRYNDPD 177
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 123-246 4.22e-18

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 80.78  E-value: 4.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 123 RSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSGVYMqlRGVNSmlgkTTPLIIMDGVPIRDGAFNSG 202
Cdd:pfam07715   3 RDTPGSVSVVTAEDIEDQGATNLADAL-RGVPGVSVSSGGGGGGSSISI--RGFGS----NRVLVLVDGVPLNSGGGGSV 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1721669871 203 NYWgdqrernngivDINPEDIENITVLKGaAAAALYGSEGVNGV 246
Cdd:pfam07715  76 DLN-----------SIDPEDIERVEVLKG-PASALYGSGAIGGV 107
SusC_RagA_signa TIGR04057
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ...
 222-252 1.84e-11

TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.


Pssm-ID: 274949 [Multi-domain]  Cd Length: 31  Bit Score: 59.13  E-value: 1.84e-11
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1721669871 222 DIENITVLKGAAAAALYGSEGVNGVVMITTK 252
Cdd:TIGR04057   1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 130-829 3.21e-11

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 67.09  E-value: 3.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 130 TTVKSDDITRTGTTNFATALYgKVPGLQIQAAPGGSTSGVYmqLRGvnsmLGKTTPLIIMDGVPIrdgafNSGNYWgdqr 209
Cdd:cd01347     3 SVITAEDIEKQPATSLADLLR-RIPGVSVTRGGGGGGSTIS--IRG----FGPDRTLVLVDGLPL-----ASSNYG---- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 210 eRNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKNnkkGFSVDVNANYFQDQVAylprfqNTRGTGFp 289
Cdd:cd01347    67 -RGVDLNTIPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTD---EFGGSVTAGYGSDNSG------SSGGGGF- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 290 sqvpgyYTSDANGFNTQQYADANGNMYRALVQGNLNFGPVFDGKPIIAWDGVVrpySAQPDRyknlfqkannstqtvais 369
Cdd:cd01347   135 ------DVSGALADDGAFGARLYGAYRDGDGTIDGDGQADDSDEERYNVAGKL---DWRPDD------------------ 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 370 snsavqSTRFSVTNQHTEGlsigsKNDKMSFSLNSTLHLGKNNDLQIIGNYYNLHVHNRPYLIDRMINNFTgmmpvfDNG 449
Cdd:cd01347   188 ------DTRLTLDAGYQDQ-----DADGPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLE------HDL 250

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 450 DWYRNKYQTSLGYKYVLNTTQSLTpdenihipsymtdilDYMWNVNKDIYDEYENRLIASITDSWTITKGLKLRgrvstd 529
Cdd:cd01347   251 NDTGWTLRANLSYSYTDNDGDPLI---------------LNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAP------ 309

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 530 ytntniYDKQSSTQPIVYGASGNYGVQNVYynmLHAdVMMEYNTKLSPDFDLTATAFYtadkekgQNTSIYTNGGlssen 609
Cdd:cd01347   310 ------FGTGPVAHTLTLGVEYRREELDEK---QTA-LYAQDTIELTDDLTLTLGLRY-------DHYDQDSKDT----- 367

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 610 wfdlaatanpisnpsappleivkDAIIGTVNINYHNYLyaegtirrdrtstmnpdnnsfvyPSANAGFIISDafklpeti 689
Cdd:cd01347   368 -----------------------IAGGTTAKKSYSHWS-----------------------PSLGLVYKLTD-------- 393

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 690 nYLKLRASWGIVGNYPDPYKANVAYLPanwgtqapgtspvlttnTNFNIYGNLNIRPEKKNEYEFGLTGQlLHSRLGFDA 769
Cdd:cd01347   394 -GLSLYASYSQGFRAPSLGELYGGGSH-----------------GGTAAVGNPNLKPEKSKQYELGLKYD-PGDGLTLSA 454

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 770 TFFTNTINDQILNLALAYSQGAVSQLNNVGKLSNKGFELSLNATPIDlkdfKWSFILNYA 829
Cdd:cd01347   455 ALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDLTD----GLGLTGSYT 510
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 33-113 9.35e-10

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 56.06  E-value: 9.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  33 VSGQITDSL-GTGLPGVTVSVNDPKGNVISGTDGHYQIKA-KDGT-TLTFMYVGYETKTVIV---NQDEINVSLSAQTNE 106
Cdd:pfam13715   1 ISGTVVDENtGEPLPGATVYVKGTTKGTVTDADGNFELKNlPAGTyTLVVSFVGYKTQEKKVtvsNDNTLDVNFLLKEDA 80


                  ....*..
gi 1721669871 107 AGTDVVV 113
Cdd:pfam13715  81 LLLDEVV 87
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 447-832 4.50e-09

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 60.17  E-value: 4.50e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 447 DNGDWYRNKYQTSLGYKYVLNTTQSLTPDENIHIPSYMTDILDYMWNVNKDIYDEYENRLIASITDSWTITKGLKLRGRV 526
Cdd:pfam00593   4 LSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 527 STDYTNTNIYDKQsstqpivygASGNYGVQNVYYNMLHADVMMEYNTKLSPDFDLTATAFYTADkekgqntsiytnGGLS 606
Cdd:pfam00593  84 GLRYSSLDGDYTS---------NSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVE------------LRTA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 607 SENWFDLAATANPISNPSAPPLEIVKD------AIIGTVNINYHNYLYAEGTIRRDRTSTMNPDNN----------SFVY 670
Cdd:pfam00593 143 GLDYRRLDDDAYDPYDPANPSSSSYSDtttdsyGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNgggdnfsrsySAFS 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 671 PSANAGFIISDAfklpetinyLKLRASWGIVGNYPDPYkanvaylpanwgtqaPGTSPVLTTNTNFNIYGNLNIRPEKKN 750
Cdd:pfam00593 223 PRLGLVYKPTDN---------LSLYASYSRGFRAPSLG---------------ELYGSGSGGGGGAVAGGNPDLKPETSD 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 751 EYEFGLTgqLLHSRLGFDATFFTNTINDQILNLALA-YSQGAVSQLNNVGKLSNKGFELSLNATPidlkdfkWSFILNYA 829
Cdd:pfam00593 279 NYELGLK--YDDGRLSLSLALFYIDIKNLITSDPDGpGLGGTVYTYTNVGKARIRGVELELSGRL-------WGLGLSGG 349


                  ...
gi 1721669871 830 NYS 832
Cdd:pfam00593 350 GYT 352
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 102-260 8.20e-08

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 56.30  E-value: 8.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 102 AQTNEAGTDVVVTAFGMKRSERSLGYAATTvkSDDITRTGTTNFATALYGKVPGLQIQaapGGSTSGVY-----MQLRGv 176
Cdd:PRK13528   28 SSDDDNGETMVVEATAEQELKQQPGVSIIT--AEDIKKRPPVNDLSDIIRKMPGVNLT---GNSASGTRgnnrqIDIRG- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 177 nsmLGKTTPLIIMDGVPIRdgAFNSGNY-W-GDQRERNngivDIN---PEDIENITVLKGAAAAAlYGSEGVNGVVMITT 251
Cdd:PRK13528  102 ---MGPENTLILIDGVPVT--SRNSVRYsWrGERDTRG----DTNwvpPEMVERIEVIRGPAAAR-YGSGAAGGVVNIIT 171


                  ....*....
gi 1721669871 252 KSGKNNKKG 260
Cdd:PRK13528  172 KRPTNDWHG 180
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 111-269 4.60e-07

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 53.94  E-value: 4.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAapGGSTSGVYMQLRGvnsmLGKTTPLIIMD 190
Cdd:TIGR01785   4 VTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADAL-NTVPGVDVTG--GGRPPGQSINIRG----LQDNRVLVVVD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVPirdgafnsGNYwgDQRERNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKSGKN---NKKGFSVDVNA 267
Cdd:TIGR01785  77 GAR--------QNY--QRGGAHNGSLFVDPELLKRIEIVKGPSSS-LYGSGALGGVVAFRTKDAADllrPGQLFGGLAKL 145


                  ..
gi 1721669871 268 NY 269
Cdd:TIGR01785 146 SY 147
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
717-829 8.50e-07

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 53.01  E-value: 8.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 717 ANWGTqapGTSPVLTTNTNFNIYGNLNIRPEKKNEYEFGLTGQLlHSRLGFDATFFTNTINDQILNLALAYSQGAVSQln 796
Cdd:COG4772   449 ANVSR---GFEPPTFGDLAYGNGGNPDLKPEKSWNYELGTRGRI-GNGLSAEVALFYIDYDNELGSCSAAGGDRSTFT-- 522

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1721669871 797 NVGKLSNKGFELSLNATPIDLKDFKWSFILNYA 829
Cdd:COG4772   523 NAGETRHQGLELALDYDLLKGGGLGLPLFAAYT 555
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
110-260 1.37e-06

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 52.34  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 110 DVVVTAfgmKRSER-SLGyaATTVKSDDITRTGTTNFATALYGKVPGLQIQaapGGSTSGVY-----MQLRGvnsmLGKT 183
Cdd:PRK13524   40 TIVVTA---AEQNLqAPG--VSTITAEDIRKRPPANDVSEIIRTMPGVNLT---GNSTSGQRgnnrqIDIRG----MGPE 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 184 TPLIIMDGVPIrdGAFNSGNY-W-GDQRERNngivDIN---PEDIENITVLKGAAAAAlYGSEGVNGVVMITTKSGKNNK 258
Cdd:PRK13524  108 NTLILIDGKPV--SSRNSVRYgWrGERDTRG----DTNwvpPEMIERIEVLRGPAAAR-YGNGAAGGVVNIITKKPTGEW 180


                  ..
gi 1721669871 259 KG 260
Cdd:PRK13524  181 HG 182
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 106-264 5.52e-06

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 50.27  E-value: 5.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 106 EAGTDVVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIqAAPGGSTSGVymQLRGVNSmlgkTTP 185
Cdd:PRK10064   28 DDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVL-KEVPGVQL-TNEGDNRKGV--SIRGLDS----SYT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 186 LIIMDG--VPIRDGAFNSGNYwgdqrernngivDIN--PED-IENITVLKGAAAAaLYGSEGVNGVV-MITTKSGKNNKK 259
Cdd:PRK10064  100 LILIDGkrVNSRNAVFRHNDF------------DLNwiPVDaIERIEVVRGPMSS-LYGSDALGGVVnIITKKIGQKWHG 166


                  ....*
gi 1721669871 260 GFSVD 264
Cdd:PRK10064  167 TVTVD 171
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
32-100 1.06e-05

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 44.58  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  32 TVSGQITDSLGTGLPGVTVSV----NDPKGNVISGTDGHYQIKA-KDGT-TLTFMYVGYETK-----TVIVNQD-EINVS 99
Cdd:pfam13620   1 TISGTVTDPSGAPVPGATVTVtntdTGTVRTTTTDADGRYRFPGlPPGTyTVTVSAPGFKTAtrtgvTVTAGQTtTLDVT 80


                  .
gi 1721669871 100 L 100
Cdd:pfam13620  81 L 81
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
98-276 3.77e-05

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 47.62  E-value: 3.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  98 VSLSAQTNEAGTD---VVVTAFG-MKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGgstSGVYMQL 173
Cdd:COG4772    10 LLAAAAAAEAATTletVVVTGSRaAEARLKDVPGSVSVVDREELENQAATSLREVL-RRVPGVNVQEEDG---FGLRPNI 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 174 --RGVNSML-GKTTplIIMDGVPIrdgafNSGNYWGDQrernnGIVDINPEDIENITVLKGaAAAALYGSEGVNGVVMIT 250
Cdd:COG4772    86 giRGLGPRRsRGIT--LLEDGIPI-----APAPYGDPA-----AYYFPDLERMERIEVLRG-AAALRYGPQTVGGAINFV 152

                         170       180
                  ....*....|....*....|....*....
gi 1721669871 251 TKSGkNNKKGFSVDVNA---NYFQDQVAY 276
Cdd:COG4772   153 TRTI-PTAFGGELRVTGgsfGYRRTHASV 180
Peptidase_M14NE-CP-C_like cd11308
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ...
 33-100 6.41e-05

Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.


Pssm-ID: 200604 [Multi-domain]  Cd Length: 76  Bit Score: 42.13  E-value: 6.41e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1721669871  33 VSGQITDSLGTGLPGVTVSVNDPKGNVISGTDGHYQIKAKDGT-TLTFMYVGYE--TKTVIVNQD----EINVSL 100
Cdd:cd11308     2 IKGFVTDATGNPIANATISVEGINHDVTTAKDGDYWRLLLPGTyNVTASAPGYQpvTKTVTVPNNfsatVVNFTL 76
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 94-323 1.09e-04

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 46.25  E-value: 1.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871  94 DEINVSLSAQTNEAGTDVVVTAfgmkrserslgyAATTVKS-DDITRTGTTNfATALYGKVPGLQIQAAPGGSTSGVYMq 172
Cdd:TIGR01786   1 DTITVTATRTADPQRRDLSVTP------------ASVSVISrEQLKSQQVRN-LRDLLRYEPGVSVVEGGRGGSQGINI- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 173 lRGVnsmlGKTTPLIIMDGVPirdgafnSGNYWGDQRERNNGIVDINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTK 252
Cdd:TIGR01786  67 -RGL----DKNRVAVLVDGIR-------QNTSYGGQGSTFYAINSIDPELIKSIEIVKGASSS-LYGSGALGGVVAFRTK 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 253 SGKN---NKKGFSVDVNANY------FQDQVAYLPRFQNTRGTgfpsqvpgYYTSDANGFNTQQYADANGNMYRALVQGN 323
Cdd:TIGR01786 134 DAADllkPGKDLGGLSKLGYssannrFTQSVAAAGRNDDVDAL--------VQATYRRGHELKNGNKANIGNESKRSKPN 205
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
130-266 1.86e-04

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 45.25  E-value: 1.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 130 TTVKSDDITRTGTTNFATALYGkVPGLQIQAAPGGStsGVYMQLRGVNSMLGkttplIIMDGvpIRDGAFNSgnywgdqr 209
Cdd:COG4774    14 TVVTRELIEDQGATSLADALRN-VPGVTFGAGEGGN--GDSFSIRGFSASGD-----IYVDG--LRDPGQYR-------- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 210 ernngivdINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTKS-------------GKNNKKGFSVDVN 266
Cdd:COG4774    76 --------RDTFNLERVEVLKGPASV-LYGRGSPGGVINLVTKRptdepftevtltyGSDGQRRATLDVN 136
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
717-829 2.27e-04

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 45.25  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 717 ANWGT--QAPGTSPVLTTNTNfniygnlNIRPEKKNEYEFGLTGQLLHSRLGFDATFFTNTINDqilnlALAYSQGAVSQ 794
Cdd:COG4774   421 ASYSTsfNPGGGAPSLSNAGQ-------ALDPEKSRQYEVGVKWDLLDGRLSLTAALFRIEKTN-----VRTTDPANPGV 488

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1721669871 795 LNNVGKLSNKGFELSLNATPIDlkdfKWSFILNYA 829
Cdd:COG4774   489 YVQTGEQRSRGVELEATGELTP----GWSVLAGYT 519
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 128-360 7.84e-04

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 43.17  E-value: 7.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 128 AATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSGVYmQLRGVNSMLGKTTplIIMDGVPirdGAFNSGNYWgd 207
Cdd:TIGR01783   5 SVSVITRQELEDQQAGSLSEAL-QRVPGVVVGGSGGTTQFGNI-TIRGFGLEVDIDN--VYLDGVP---LLSRGNLAI-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 208 qrernngivdINPEDIENITVLKGAAAAaLYGSEGVNGVVMITTK-------------SGKNNKKGFSVDVNANYFQDQV 274
Cdd:TIGR01783  76 ----------VDPAMVERVEVLRGPASL-LYGGSAPGGVINIVTKrpqdepkgsvtfgAGTRSGYRTAFDLGGPLGADGT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 275 AYLpRFqNTRGTGFPSQVPGyYTSDANGFNTQQYADANgnmyralVQGNLNFGPVFDGKPIIAWDGVV------RPYSAQ 348
Cdd:TIGR01783 145 FRG-RL-NGARQDGDSFYDG-AGEETRLGATATDWQLD-------DRTLLRLGAYYQKERDRGGYGGLpasggtSGRDLS 214

                         250
                  ....*....|..
gi 1721669871 349 PDRYKNLFQKAN 360
Cdd:TIGR01783 215 SDRYLGTSSNRN 226
PRK13486 PRK13486
TonB-dependent receptor;
111-267 9.95e-04

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 43.09  E-value: 9.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 111 VVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALYGkVPGLQIQAAPGgSTSGVYMQLRGVNSmlgkTTPLIIMD 190
Cdd:PRK13486   28 MIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDVESGTG-KTGGLEISIRGMPA----SYTLILID 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 191 GVpirdgafnsgnywgdqreRNNGIVDINPED--------------IENITVLKGAAAAaLYGSEGVNGVVMITTKsgKN 256
Cdd:PRK13486  102 GV------------------RQGGSSDVTPNGfsamntgfmpplaaIERIEVIRGPMST-LYGSDAMGGVVNIITR--KN 160

                         170
                  ....*....|.
gi 1721669871 257 NKKgFSVDVNA 267
Cdd:PRK13486  161 ADK-WLSSVNA 170
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 109-252 1.89e-03

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 42.19  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 109 TDVVVTAFGMKRSERSLGYAATTVKSDDITRTGTTNFATALyGKVPGLQIQAAPGGSTSGVYMqlRGVnsmlgkTTPLII 188
Cdd:COG4773    49 AKSSSTATKLDTPLRETPQSVSVVTRQLIEDQGATTLDDAL-RNVPGVTVSSYDGGGRDSFSI--RGF------SIDNYL 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1721669871 189 MDGVPIrdgafnsgNYWGDQRernngivdINPEDIENITVLKGaAAAALYGSEGVNGVVMITTK 252
Cdd:COG4773   120 RDGLPL--------GGFGGGQ--------PDTANLERVEVLKG-PAGLLYGAGSPGGLVNLVTK 166
PRK13483 PRK13483
ligand-gated channel protein;
737-828 6.61e-03

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 40.53  E-value: 6.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721669871 737 NIYGNLNIRPEKKNEYEFGLTGQlLHSRLGFDATFFTNTINDQILNLALAYSQ--------GAVSQLN-NVGKLSNKGFE 807
Cdd:PRK13483  448 NIYGNPDLKPETSLNKELGLYYD-LGSGLTASLTVFYNEFKDKITRVACPATQctdgpnqfGADPTTYvNIDEAVTQGVE 526

                          90       100
                  ....*....|....*....|.
gi 1721669871 808 LSLnATPIDLkdfKWSFILNY 828
Cdd:PRK13483  527 ASL-SYPITS---TLSLSGNY 543
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH