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Conserved domains on  [gi|1590860123|gb|QBL48681|]
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helix-turn-helix domain-containing protein [Klebsiella sp. PO552]

Protein Classification

transposase family protein( domain architecture ID 1750148)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0015074|GO:0032196|GO:0003677

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_ISNCY_2 super family cl41340
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
 1-96 8.07e-27

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


The actual alignment was detected with superfamily member NF033594:

Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 100.63  E-value: 8.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590860123   1 MELTRRQCSRLIKRYRELGPAGLVSRRRGKPGNHQLNTTIRDQALQLIRSRGRGMNPTAIWRILTTEYSVRISKETVRKL 80
Cdd:NF033594   20 LGLSERQVRRLLKRYREEGAAGLVHGNRGRPPNNRLPDELRERVLALYRERYYDFGPTLALEKLRERHGISLSRETVRRW 99

                          90
                  ....*....|....*.
gi 1590860123  81 MITEKAWHPRPSFRPD 96
Cdd:NF033594  100 MIEAGLWSPRKQRRPK 115
 
Name Accession Description Interval E-value
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
 1-96 8.07e-27

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 100.63  E-value: 8.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590860123   1 MELTRRQCSRLIKRYRELGPAGLVSRRRGKPGNHQLNTTIRDQALQLIRSRGRGMNPTAIWRILTTEYSVRISKETVRKL 80
Cdd:NF033594   20 LGLSERQVRRLLKRYREEGAAGLVHGNRGRPPNNRLPDELRERVLALYRERYYDFGPTLALEKLRERHGISLSRETVRRW 99

                          90
                  ....*....|....*.
gi 1590860123  81 MITEKAWHPRPSFRPD 96
Cdd:NF033594  100 MIEAGLWSPRKQRRPK 115
HTH_32 pfam13565
Homeodomain-like domain;
9-81 1.67e-05

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 39.20  E-value: 1.67e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1590860123  9 SRLIKRYRELGPAGLVSR-RRGKPgnHQLNTTIRDQALQLIRSRGRgMNPTAIWRILTTEYSVRISKETVRKLM 81
Cdd:pfam13565  3 YRWRKRYNEEGLEGLEDRpRRGRP--RKLTDEQEARLLALLCEEPR-WSPRLLAERLEEEFGVKVSRSTVRRIL 73
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 3-95 3.63e-05

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 40.61  E-value: 3.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590860123   3 LTRRQCSRLIKRYRELGPAGLVSRRRGKPgNHQLNTTIRDQALQLIRSR----GRGMNPTAIWRILTTEYSVRISKETVR 78
Cdd:COG3415    50 VSRSTVYRWLKRYREGGLAGLKDRPRGGR-PSKLSDEQRERLLELLREKspdqGSRWTLAELAELLEEEFGVEVSPSTVR 128

                          90
                  ....*....|....*..
gi 1590860123  79 KLMITEKAWHPRPSFRP 95
Cdd:COG3415   129 RLLKRLGLSYKKPRPRA 145
 
Name Accession Description Interval E-value
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
 1-96 8.07e-27

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 100.63  E-value: 8.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590860123   1 MELTRRQCSRLIKRYRELGPAGLVSRRRGKPGNHQLNTTIRDQALQLIRSRGRGMNPTAIWRILTTEYSVRISKETVRKL 80
Cdd:NF033594   20 LGLSERQVRRLLKRYREEGAAGLVHGNRGRPPNNRLPDELRERVLALYRERYYDFGPTLALEKLRERHGISLSRETVRRW 99

                          90
                  ....*....|....*.
gi 1590860123  81 MITEKAWHPRPSFRPD 96
Cdd:NF033594  100 MIEAGLWSPRKQRRPK 115
HTH_32 pfam13565
Homeodomain-like domain;
9-81 1.67e-05

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 39.20  E-value: 1.67e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1590860123  9 SRLIKRYRELGPAGLVSR-RRGKPgnHQLNTTIRDQALQLIRSRGRgMNPTAIWRILTTEYSVRISKETVRKLM 81
Cdd:pfam13565  3 YRWRKRYNEEGLEGLEDRpRRGRP--RKLTDEQEARLLALLCEEPR-WSPRLLAERLEEEFGVKVSRSTVRRIL 73
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 3-95 3.63e-05

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 40.61  E-value: 3.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590860123   3 LTRRQCSRLIKRYRELGPAGLVSRRRGKPgNHQLNTTIRDQALQLIRSR----GRGMNPTAIWRILTTEYSVRISKETVR 78
Cdd:COG3415    50 VSRSTVYRWLKRYREGGLAGLKDRPRGGR-PSKLSDEQRERLLELLREKspdqGSRWTLAELAELLEEEFGVEVSPSTVR 128

                          90
                  ....*....|....*..
gi 1590860123  79 KLMITEKAWHPRPSFRP 95
Cdd:COG3415   129 RLLKRLGLSYKKPRPRA 145
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 1-30 2.98e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 32.95  E-value: 2.98e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 1590860123  1 MELTRRQCSRLIKRYRELGPAGLVSRRRGK 30
Cdd:pfam13518 22 FGISRSTVYRWIRRYREGGLEGLLPRRRRP 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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