hemoglobin linker chain, partial [Auchenoplax crinita]
LDL receptor domain-containing protein( domain architecture ID 10060319)
Low Density Lipoprotein (LDL) receptor class A domain is a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; similar to Bos taurus CD320 antigen; Low Density Lipoprotein (LDL) receptor class A domain is a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; similar to Bos taurus CD320 antigen; Low Density Lipoprotein (LDL) receptor class A domain is a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; similar to Caenorhabditis elegans LDL receptor repeat-containing protein egg-2
List of domain hits
Name | Accession | Description | Interval | E-value | |||
hemoglobin_linker_C super family | cl17028 | Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is ... |
175-274 | 1.01e-18 | |||
Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is restricted to annelid worms, and participates in the formation of the large erythrocruorin respiratory complex. Via its N-terminal coiled-coil segment (not included in this model), the molecule forms trimers, which are part of a scaffold organizing the overall complex architecture; the latter encompasses 36 linkers and 144 hemoglobins in total. This C-terminal globular domain is involved in trimerization, and also interacts with globins and other C-terminal globular linker domains of neighboring trimers. The structure resembles that of nitrophorins and lipocalins. The actual alignment was detected with superfamily member cd11673: Pssm-ID: 327373 Cd Length: 120 Bit Score: 79.72 E-value: 1.01e-18
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LDLa | cd00112 | Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central ... |
117-152 | 2.85e-05 | |||
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about 40 amino acids are present in the N-terminal of this multidomain membrane protein; other homologous domains occur in related receptors, including the very low-density lipoprotein receptor and the LDL receptor-related protein/alpha 2-macroglobulin receptor, and in proteins which are functionally unrelated, such as the C9 component of complement; the binding of calcium is required for in vitro formation of the native disulfide isomer and is necessary in establishing and maintaining the modular structure : Pssm-ID: 238060 Cd Length: 35 Bit Score: 40.27 E-value: 2.85e-05
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Name | Accession | Description | Interval | E-value | |||
hemoglobin_linker_C | cd11673 | Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is ... |
175-274 | 1.01e-18 | |||
Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is restricted to annelid worms, and participates in the formation of the large erythrocruorin respiratory complex. Via its N-terminal coiled-coil segment (not included in this model), the molecule forms trimers, which are part of a scaffold organizing the overall complex architecture; the latter encompasses 36 linkers and 144 hemoglobins in total. This C-terminal globular domain is involved in trimerization, and also interacts with globins and other C-terminal globular linker domains of neighboring trimers. The structure resembles that of nitrophorins and lipocalins. Pssm-ID: 212563 Cd Length: 120 Bit Score: 79.72 E-value: 1.01e-18
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Eryth_link_C | pfam16915 | Annelid erythrocruorin linker subunit C-terminus; This domain is found in linker subunits of ... |
158-274 | 9.33e-18 | |||
Annelid erythrocruorin linker subunit C-terminus; This domain is found in linker subunits of the erythrocruorin respiratory complex in annelid worms. Pssm-ID: 319001 Cd Length: 120 Bit Score: 77.39 E-value: 9.33e-18
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LDLa | cd00112 | Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central ... |
117-152 | 2.85e-05 | |||
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about 40 amino acids are present in the N-terminal of this multidomain membrane protein; other homologous domains occur in related receptors, including the very low-density lipoprotein receptor and the LDL receptor-related protein/alpha 2-macroglobulin receptor, and in proteins which are functionally unrelated, such as the C9 component of complement; the binding of calcium is required for in vitro formation of the native disulfide isomer and is necessary in establishing and maintaining the modular structure Pssm-ID: 238060 Cd Length: 35 Bit Score: 40.27 E-value: 2.85e-05
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LDLa | smart00192 | Low-density lipoprotein receptor domain class A; Cysteine-rich repeat in the low-density ... |
117-151 | 4.92e-05 | |||
Low-density lipoprotein receptor domain class A; Cysteine-rich repeat in the low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. The N-terminal type A repeats in LDL receptor bind the lipoproteins. Other homologous domains occur in related receptors, including the very low-density lipoprotein receptor and the LDL receptor-related protein/alpha 2-macroglobulin receptor, and in proteins which are functionally unrelated, such as the C9 component of complement. Mutations in the LDL receptor gene cause familial hypercholesterolemia. Pssm-ID: 197566 Cd Length: 33 Bit Score: 39.54 E-value: 4.92e-05
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Ldl_recept_a | pfam00057 | Low-density lipoprotein receptor domain class A; |
116-151 | 2.48e-03 | |||
Low-density lipoprotein receptor domain class A; Pssm-ID: 395011 Cd Length: 37 Bit Score: 34.92 E-value: 2.48e-03
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Name | Accession | Description | Interval | E-value | |||
hemoglobin_linker_C | cd11673 | Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is ... |
175-274 | 1.01e-18 | |||
Globular domain of extracellular hemoglobin linker; This family of hemoglobin linker chains is restricted to annelid worms, and participates in the formation of the large erythrocruorin respiratory complex. Via its N-terminal coiled-coil segment (not included in this model), the molecule forms trimers, which are part of a scaffold organizing the overall complex architecture; the latter encompasses 36 linkers and 144 hemoglobins in total. This C-terminal globular domain is involved in trimerization, and also interacts with globins and other C-terminal globular linker domains of neighboring trimers. The structure resembles that of nitrophorins and lipocalins. Pssm-ID: 212563 Cd Length: 120 Bit Score: 79.72 E-value: 1.01e-18
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Eryth_link_C | pfam16915 | Annelid erythrocruorin linker subunit C-terminus; This domain is found in linker subunits of ... |
158-274 | 9.33e-18 | |||
Annelid erythrocruorin linker subunit C-terminus; This domain is found in linker subunits of the erythrocruorin respiratory complex in annelid worms. Pssm-ID: 319001 Cd Length: 120 Bit Score: 77.39 E-value: 9.33e-18
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LDLa | cd00112 | Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central ... |
117-152 | 2.85e-05 | |||
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about 40 amino acids are present in the N-terminal of this multidomain membrane protein; other homologous domains occur in related receptors, including the very low-density lipoprotein receptor and the LDL receptor-related protein/alpha 2-macroglobulin receptor, and in proteins which are functionally unrelated, such as the C9 component of complement; the binding of calcium is required for in vitro formation of the native disulfide isomer and is necessary in establishing and maintaining the modular structure Pssm-ID: 238060 Cd Length: 35 Bit Score: 40.27 E-value: 2.85e-05
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LDLa | smart00192 | Low-density lipoprotein receptor domain class A; Cysteine-rich repeat in the low-density ... |
117-151 | 4.92e-05 | |||
Low-density lipoprotein receptor domain class A; Cysteine-rich repeat in the low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. The N-terminal type A repeats in LDL receptor bind the lipoproteins. Other homologous domains occur in related receptors, including the very low-density lipoprotein receptor and the LDL receptor-related protein/alpha 2-macroglobulin receptor, and in proteins which are functionally unrelated, such as the C9 component of complement. Mutations in the LDL receptor gene cause familial hypercholesterolemia. Pssm-ID: 197566 Cd Length: 33 Bit Score: 39.54 E-value: 4.92e-05
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Ldl_recept_a | pfam00057 | Low-density lipoprotein receptor domain class A; |
116-151 | 2.48e-03 | |||
Low-density lipoprotein receptor domain class A; Pssm-ID: 395011 Cd Length: 37 Bit Score: 34.92 E-value: 2.48e-03
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Blast search parameters | ||||
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