|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
16-348 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 546.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 16 PQAQDLRCFNTLGLASHAPAFVALTEPSQLPALSAlAPRFRQL--VVLGGGSNVVLPASIDGLVAQVRLPGVRLVGQCAD 93
Cdd:PRK00046 4 QMNHSLKPLNTFGIDARARHLVEAESEEQLLEALA-DARAAGLpvLVLGGGSNVLFTEDFDGTVLLNRIKGIEVLSEDDD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 94 AWVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEMGAAECRFA 173
Cdd:PRK00046 83 AWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECRFG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 174 YRDSFFKHQEPGAWVIGSVRFALPRPWQPVLDYPDLQRhaaLDGAAPTARAVYDAVCAIRRAKLPDPAVVGNAGSFFKNP 253
Cdd:PRK00046 163 YRDSIFKHEYPDRYAITAVGFRLPKQWQPVLDYGDLAR---LDPDTVTAQDVFDAVCAIRRSKLPDPKVLGNAGSFFKNP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 254 LVDAGTRQALLGRFPGLVSYPQPDGRYKLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDV 333
Cdd:PRK00046 240 VVSAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLALARHIQQDV 319
|
330
....*....|....*
gi 6707716 334 ERRYGVRLEPEPVVV 348
Cdd:PRK00046 320 REKFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
12-348 |
6.08e-112 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 326.97 E-value: 6.08e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 12 APLAPqaqdlrcFNTLGLASHAPAFVALTEPSQLPA-LSALAPRFRQLVVLGGGSNVVLP-ASIDGLVAQVR-LPGVRLv 88
Cdd:COG0812 1 EPLAP-------HTTFRIGGPADLLVEPASEEELAAlLRAAREAGLPVLVLGGGSNLLVRdDGFDGLVIRLGrLKGIEV- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 89 gqcADAWVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDvKGGRWVEMGAA 168
Cdd:COG0812 73 ---DDGVLVTAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 169 ECRFAYRDSFFKHQEpgaWVIGSVRFALPRpwqpvldypdlqrhaaldGAAPTARAVYDAVCAIRRAKlpDPAVVGNAGS 248
Cdd:COG0812 149 ECGFGYRDSIFKRER---YIILSVTFRLKK------------------GDPAEIAAVMDAVLAIRRSK--QPLELPSAGS 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 249 FFKNPlvdagtrqallgrfPGlvsypqpdgrykLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAA 328
Cdd:COG0812 206 FFKNP--------------PG------------DSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGGATAADVLALIEE 259
|
330 340
....*....|....*....|
gi 6707716 329 IQGDVERRYGVRLEPEPVVV 348
Cdd:COG0812 260 VQARVKEKFGVELEPEVRII 279
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
24-344 |
8.40e-68 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 214.62 E-value: 8.40e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 24 FNTLGLASHAPAFValtEPSQLPALSALAPRFRQ----LVVLGGGSNV-VLPASIDGLVAqvrLPGVRLVGQCADAWVVE 98
Cdd:TIGR00179 4 FTTYKIGGNARHIV---CPESIEQLVNVLDNAKEedqpLLILGEGSNLlILDDGRGGVII---NLGKGIDIEDDEGEYVH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 99 AAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGG-RWVEmgAAECRFAYRDS 177
Cdd:TIGR00179 78 VGGGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKtEWLT--NEQLGFGYRTS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 178 FFKHQEPGawvigsvrFALPRPWQPVLDYPDlqrhaALDGAAPTARAVYDAVCAIRRAKLPDPavvgNAGSFFKNPLvda 257
Cdd:TIGR00179 156 IFQHKYVG--------LVLKAEFQLTLGFGT-----RLDPETITAQQVFNKVCRMRTSHYPDP----NAGSFFKNPS--- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 258 gtrqallgrfpglvsyPQPdgryklaAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRY 337
Cdd:TIGR00179 216 ----------------PNH-------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDNAKSEDVLDLIEHVKAEVGEKY 272
|
....*..
gi 6707716 338 GVRLEPE 344
Cdd:TIGR00179 273 GILLEPE 279
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
225-348 |
5.66e-41 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 139.02 E-value: 5.66e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 225 VYDAVCAIRRAKL-PDPAVVGNAGSFFKNPLvdagtrqallgrfpglvsypqpdgryKLAAGWLIDQCGWKGRQLGAAGV 303
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNPV--------------------------GHSAGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 6707716 304 HDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVV 348
Cdd:pfam02873 55 SEKHANFLVNTGGATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| murB |
PRK00046 |
UDP-N-acetylmuramate dehydrogenase; |
16-348 |
0e+00 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 234593 [Multi-domain] Cd Length: 334 Bit Score: 546.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 16 PQAQDLRCFNTLGLASHAPAFVALTEPSQLPALSAlAPRFRQL--VVLGGGSNVVLPASIDGLVAQVRLPGVRLVGQCAD 93
Cdd:PRK00046 4 QMNHSLKPLNTFGIDARARHLVEAESEEQLLEALA-DARAAGLpvLVLGGGSNVLFTEDFDGTVLLNRIKGIEVLSEDDD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 94 AWVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEMGAAECRFA 173
Cdd:PRK00046 83 AWYLHVGAGENWHDLVLWTLQQGMPGLENLALIPGTVGAAPIQNIGAYGVELKDVCDYVEALDLATGEFVRLSAAECRFG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 174 YRDSFFKHQEPGAWVIGSVRFALPRPWQPVLDYPDLQRhaaLDGAAPTARAVYDAVCAIRRAKLPDPAVVGNAGSFFKNP 253
Cdd:PRK00046 163 YRDSIFKHEYPDRYAITAVGFRLPKQWQPVLDYGDLAR---LDPDTVTAQDVFDAVCAIRRSKLPDPKVLGNAGSFFKNP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 254 LVDAGTRQALLGRFPGLVSYPQPDGRYKLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDV 333
Cdd:PRK00046 240 VVSAEQFEALLAQYPDIPHYPQADGSVKLAAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLALARHIQQDV 319
|
330
....*....|....*
gi 6707716 334 ERRYGVRLEPEPVVV 348
Cdd:PRK00046 320 REKFGVELEPEPRFI 334
|
|
| MurB |
COG0812 |
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ... |
12-348 |
6.08e-112 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440574 [Multi-domain] Cd Length: 279 Bit Score: 326.97 E-value: 6.08e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 12 APLAPqaqdlrcFNTLGLASHAPAFVALTEPSQLPA-LSALAPRFRQLVVLGGGSNVVLP-ASIDGLVAQVR-LPGVRLv 88
Cdd:COG0812 1 EPLAP-------HTTFRIGGPADLLVEPASEEELAAlLRAAREAGLPVLVLGGGSNLLVRdDGFDGLVIRLGrLKGIEV- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 89 gqcADAWVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDvKGGRWVEMGAA 168
Cdd:COG0812 73 ---DDGVLVTAGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLD-RTGEVRTLSAE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 169 ECRFAYRDSFFKHQEpgaWVIGSVRFALPRpwqpvldypdlqrhaaldGAAPTARAVYDAVCAIRRAKlpDPAVVGNAGS 248
Cdd:COG0812 149 ECGFGYRDSIFKRER---YIILSVTFRLKK------------------GDPAEIAAVMDAVLAIRRSK--QPLELPSAGS 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 249 FFKNPlvdagtrqallgrfPGlvsypqpdgrykLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAA 328
Cdd:COG0812 206 FFKNP--------------PG------------DSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNRGGATAADVLALIEE 259
|
330 340
....*....|....*....|
gi 6707716 329 IQGDVERRYGVRLEPEPVVV 348
Cdd:COG0812 260 VQARVKEKFGVELEPEVRII 279
|
|
| murB |
PRK13903 |
UDP-N-acetylmuramate dehydrogenase; |
2-348 |
1.11e-71 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237552 [Multi-domain] Cd Length: 363 Bit Score: 227.15 E-value: 1.11e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 2 STVPARIEPVAPLAPqaqdlrcFNTLGLASHAPAFVALTEPSQL-PALSALAPRFRQLVVLGGGSNVVLP-ASIDGLVAQ 79
Cdd:PRK13903 9 AFAGAEVAEDVPLAP-------LTTLRVGGPARRLVTCTSTEELvAAVRELDAAGEPLLVLGGGSNLVIAdDGFDGTVVR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 80 VRLPGVRLvgQCADAwVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKG 159
Cdd:PRK13903 82 VATRGVTV--DCGGG-LVRAEAGAVWDDVVARTVEAGLGGLECLSGIPGSAGATPVQNVGAYGQEVSDTITRVRLLDRRT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 160 GRWVEMGAAECRFAYRDSFFKHQEpgAWVIGSVRFAL-PRPWQPVLDYPDLQRhaALDGAAPT---ARAVYDAVCAIRRA 235
Cdd:PRK13903 159 GEVRWVPAADLGFGYRTSVLKHSD--RAVVLEVEFQLdPSGLSAPLRYGELAR--ALGVEPGErvpPAAVREAVLALRAG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 236 K--LPDPA--VVGNAGSFFKNPLVDAGTRQALLGRFPGLV-----SYPQPDGRYKLAAGWLIDQCGW-KGRQLGAAGVH- 304
Cdd:PRK13903 235 KgmVLDPAdhDTWSAGSFFTNPVVSPAVAERLAARVAERLgdpvpRYPAGDGGVKLSAAWLIERAGFgKGYPGGGAPARl 314
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 6707716 305 -DRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVV 348
Cdd:PRK13903 315 sTKHTLALTNRGGATTADLVALAREVRDGVRDAFGVTLVPEPVLV 359
|
|
| murB |
TIGR00179 |
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ... |
24-344 |
8.40e-68 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 272945 [Multi-domain] Cd Length: 284 Bit Score: 214.62 E-value: 8.40e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 24 FNTLGLASHAPAFValtEPSQLPALSALAPRFRQ----LVVLGGGSNV-VLPASIDGLVAqvrLPGVRLVGQCADAWVVE 98
Cdd:TIGR00179 4 FTTYKIGGNARHIV---CPESIEQLVNVLDNAKEedqpLLILGEGSNLlILDDGRGGVII---NLGKGIDIEDDEGEYVH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 99 AAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGG-RWVEmgAAECRFAYRDS 177
Cdd:TIGR00179 78 VGGGENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKtEWLT--NEQLGFGYRTS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 178 FFKHQEPGawvigsvrFALPRPWQPVLDYPDlqrhaALDGAAPTARAVYDAVCAIRRAKLPDPavvgNAGSFFKNPLvda 257
Cdd:TIGR00179 156 IFQHKYVG--------LVLKAEFQLTLGFGT-----RLDPETITAQQVFNKVCRMRTSHYPDP----NAGSFFKNPS--- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 258 gtrqallgrfpglvsyPQPdgryklaAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRY 337
Cdd:TIGR00179 216 ----------------PNH-------AGRLIEECGLKGYQIGGAAVSKQHANFLVNIDNAKSEDVLDLIEHVKAEVGEKY 272
|
....*..
gi 6707716 338 GVRLEPE 344
Cdd:TIGR00179 273 GILLEPE 279
|
|
| murB |
PRK13905 |
UDP-N-acetylmuramate dehydrogenase; |
60-344 |
6.08e-42 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237553 [Multi-domain] Cd Length: 298 Bit Score: 147.95 E-value: 6.08e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 60 VLGGGSNV-VLPASIDGLVaqvrlpgVRLVGQCADAWV----VEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAP 134
Cdd:PRK13905 59 VLGNGSNLlVRDGGIRGVV-------IRLGKGLNEIEVegnrITAGAGAPLIKLARFAAEAGLSGLEFAAGIPGTVGGAV 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 135 VQNIGAYGVELADRFHSLTAWDVKGGRwVEMGAAECRFAYRDSFFkhQEPGAWVIgSVRFALPRpwqpvldypdlqrhaa 214
Cdd:PRK13905 132 FMNAGAYGGETADVLESVEVLDRDGEI-KTLSNEELGFGYRHSAL--QEEGLIVL-SATFQLEP---------------- 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 215 ldGAAPTARAVYDAVCAIRRAKLP--DPavvgNAGSFFKNPlvdagtrqallgrfPGlvsypqpdgrykLAAGWLIDQCG 292
Cdd:PRK13905 192 --GDKEEIKARMDELLARREATQPleYP----SAGSVFKNP--------------PG------------HFAGKLIEEAG 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 6707716 293 WKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPE 344
Cdd:PRK13905 240 LKGYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWE 291
|
|
| MurB_C |
pfam02873 |
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ... |
225-348 |
5.66e-41 |
|
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 460730 [Multi-domain] Cd Length: 99 Bit Score: 139.02 E-value: 5.66e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 225 VYDAVCAIRRAKL-PDPAVVGNAGSFFKNPLvdagtrqallgrfpglvsypqpdgryKLAAGWLIDQCGWKGRQLGAAGV 303
Cdd:pfam02873 1 IRAAMLELRRRRLaKQPLDPPSAGSFFKNPV--------------------------GHSAGWLIEQAGLKGYRIGGAQV 54
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 6707716 304 HDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVV 348
Cdd:pfam02873 55 SEKHANFLVNTGGATAADVLALIEEVRERVKEKFGVELEPEVRII 99
|
|
| PRK14649 |
PRK14649 |
UDP-N-acetylmuramate dehydrogenase; |
36-348 |
4.82e-28 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173112 [Multi-domain] Cd Length: 295 Bit Score: 111.09 E-value: 4.82e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 36 FVALTEPSQLPALSALApRFRQL--VVLGGGSNV-VLPASIDGLVAQVRLPGVRLV--GQCADAWVveaAAGENWHGFVT 110
Cdd:PRK14649 24 FVEPTTPDEAIAAAAWA-EQRQLplFWLGGGSNLlVRDEGFDGLVARYRGQRWELHehGDTAEVWV---EAGAPMAGTAR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 111 ACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADrfHSLTAWD-VKGGRWVEMGAAECRFAYRDSFFKHqepgawvi 189
Cdd:PRK14649 100 RLAAQGWAGLEWAEGLPGTIGGAIYGNAGCYGGDTAT--VLIRAWLlLNGSECVEWSVHDFAYGYRTSVLKQ-------- 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 190 gsVRFALPRPWQPVLDYPDLQRHAAlDGAAPTARAvyDAVCAIRRAKLPDPAvvgNAGSFFKNPLVDAgtrqallgrfpg 269
Cdd:PRK14649 170 --LRADGITWRPPLVLAARFRLHRD-DPTALAARM--EAIAAERKQKTPAGS---SCGSVFKNPPGDS------------ 229
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6707716 270 lvsypqpdgryklaAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVV 348
Cdd:PRK14649 230 --------------AGRLIEAAGLKGTRIGDAEIATRHANYIINLGGARAADILRLIDLARTRVLAQFGIELELEVRII 294
|
|
| PRK14653 |
PRK14653 |
UDP-N-acetylmuramate dehydrogenase; |
19-344 |
2.05e-18 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237778 [Multi-domain] Cd Length: 297 Bit Score: 84.12 E-value: 2.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 19 QDLRCFNTLGLASHAPAFVALTEPSQLPALSALAPRFRQLVVLGGGSNVvLPasIDGLVAQVRLPGVRLVGQCADAWVVE 98
Cdd:PRK14653 20 EEMKCHVSFKIGGPVPLFAIPNSTNGFIETINLLKEGIEVKILGNGTNV-LP--KDEPMDFVVVSTERLDDIFVDNDKII 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 99 AAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDvkGGRWVEMGAAECRFAYRDSF 178
Cdd:PRK14653 97 CESGLSLKKLCLVAAKNGLSGFENAYGIPGSVGGAVYMNAGAYGWETAENIVEVVAYD--GKKIIRLGKNEIKFSYRNSI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 179 FKHQEPgaWVIGSVRFALPRpwqpvlDYPDLqrhaaldgaaptaraVYDAVCAIRRAKL-PDPAVVGNAGSFFKNPlvda 257
Cdd:PRK14653 175 FKEEKD--LIILRVTFKLKK------GNKNE---------------IYNLMLETMKKRVeKQPLEFPSAGSVFKRP---- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 258 gtrqallgrfpglvsypqpdgRYKLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRY 337
Cdd:PRK14653 228 ---------------------RKDFYVGSAIEKLGLKGFSIGGAQISEKHAGFIINYNNAKAEDVLKLIEYVKDKIYENY 286
|
....*..
gi 6707716 338 GVRLEPE 344
Cdd:PRK14653 287 NVELETE 293
|
|
| PRK14651 |
PRK14651 |
UDP-N-acetylmuramate dehydrogenase; |
6-344 |
2.10e-16 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237776 [Multi-domain] Cd Length: 273 Bit Score: 78.32 E-value: 2.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 6 ARIEPVaPLAPqaqdlrcFNTLGLASHAPAFVALTEpSQLPalSALAPRFRqlvVLGGGSNVVLpaSIDGLVAQVrlpgV 85
Cdd:PRK14651 2 ARVERV-PLAR-------YTTLGVGGPAELWTVETH-EQLA--EATEAPYR---VLGGGSNLLV--SDAGVPERV----I 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 86 RLVGQCADA----WVveaAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAwdVKGGR 161
Cdd:PRK14651 62 RLGGEFAEWdldgWV---GGGVPLPGLVRRAARLGLSGLEGLVGIPAQVGGAVKMNAGTRFGEMADALHTVEI--VHDGG 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 162 WVEMGAAECRFAYRDSffkHQEPGAwVIGSVRFAL-PRPWQPVLdypdlQRHAALDGAAPTARAVYDAVCAirraklpdp 240
Cdd:PRK14651 137 FHQYSPDELGFGYRHS---GLPPGH-VVTRVRLKLrPSTPEAVL-----AKMALVDAARKGQPKKKSAGCA--------- 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 241 avvgnagsfFKNPlvdagtrqallgrfPGLvsypqpdgryklAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQAR 320
Cdd:PRK14651 199 ---------FKNP--------------PGD------------SAGRLIDEAGLKGTRVGDAMISPEHGNFIVNLGGATAA 243
|
330 340
....*....|....*....|....
gi 6707716 321 DIMALAAAIQGdverRYGVRLEPE 344
Cdd:PRK14651 244 DVHALLRRVRA----RVGLPLELE 263
|
|
| PRK14652 |
PRK14652 |
UDP-N-acetylmuramate dehydrogenase; |
38-344 |
2.25e-15 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 237777 [Multi-domain] Cd Length: 302 Bit Score: 75.68 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 38 ALTEPSQLPALSALAPRFRQ----LVVLGGGSN-VVLPASIDGLVaqVRLPGvRLVGQCADAWVVEAAAGENWHGFVTAC 112
Cdd:PRK14652 38 LLVRPADPDALSALLRAVRElgvpLSILGGGANtLVADAGVRGVV--LRLPQ-DFPGESTDGGRLVLGAGAPISRLPARA 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 113 VDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEmgAAECRFAYRDSffkhQEPGAWVIGSV 192
Cdd:PRK14652 115 HAHGLVGMEFLAGIPGTLGGAVAMNAGTKLGEMKDVVTAVELATADGAGFVP--AAALGYAYRTC----RLPPGAVITRV 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 193 RFALpRPwqpvldypdlqrhaaldGAAPTARAVYDAVCAIRRAKlpDPAVVGNAGSFFKNPLVDAgtrqallgrfpglvs 272
Cdd:PRK14652 189 EVRL-RP-----------------GDVAASEALMRADRERRRRT--QPLDRPTFGSTFTNPPGDY--------------- 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6707716 273 ypqpdgryklaAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPE 344
Cdd:PRK14652 234 -----------AGRLVEAVGLKGHRVGGAIWSPVHANFVTNLGGATARDVLALVRLARARVKERFGIALETE 294
|
|
| FAD_binding_4 |
pfam01565 |
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ... |
33-159 |
4.15e-15 |
|
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.
Pssm-ID: 426326 [Multi-domain] Cd Length: 139 Bit Score: 71.46 E-value: 4.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 33 APAFVALTEPSQLPALSALAPRFR-QLVVLGGGSNVVLPASIDG--LVAQVRLPGVRLVgqCADAWVVEAAAGENWHGFV 109
Cdd:pfam01565 1 PAAVVLPESEEEVAAIVRLANENGlPVLPRGGGSSLLGGAVQTGgiVLDLSRLNGILEI--DPEDGTATVEAGVTLGDLV 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 6707716 110 TACVDNG-WDGLENLALIPGTVGAAPVQNIGAYGVEL----ADRFHSLTAWDVKG 159
Cdd:pfam01565 79 RALAAKGlLLGLDPGSGIPGTVGGAIATNAGGYGSEKygltRDNVLGLEVVLADG 133
|
|
| PRK12436 |
PRK12436 |
UDP-N-acetylmuramate dehydrogenase; |
1-344 |
4.22e-13 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 171497 [Multi-domain] Cd Length: 305 Bit Score: 68.88 E-value: 4.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 1 MSTVPARIEPVAPLAPQAQD--LRCFNTLGLASHAPAFVALTEPSQLPALSALAPRFR-QLVVLGGGSNVVLP-ASIDGL 76
Cdd:PRK12436 3 MQEVYEYLSTVLPEGHVKQDemLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNiPVTFLGNGSNVIIKdGGIRGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 77 ------VAQVRLPGVRLVGQCADAwVVEAAagenwhgfvTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELAdrfH 150
Cdd:PRK12436 83 tvslihITGVTVTGTTIVAQCGAA-IIDVS---------RIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEIS---F 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 151 SLTAWDV--KGGRWVEMGAAECRFAYRDSFFKHQEpgaWVIGSVRFALPrpwqpvldypdlqrhaalDGAAPTARAVYDA 228
Cdd:PRK12436 150 VLTEAVVmtGDGELRTLTKEAFEFGYRKSVFANNH---YIILEARFELE------------------EGVYEEIKAKMDD 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 229 VCAIRRAKlpDPAVVGNAGSFFKNPlvdagtrqallgrfpglvsypqPDGryklAAGWLIDQCGWKGRQLGAAGVHDRQA 308
Cdd:PRK12436 209 LTFKRESK--QPLEYPSCGSVFKRP----------------------PNN----FAGKLIQESGLQGKRIGGVEVSLKHA 260
|
330 340 350
....*....|....*....|....*....|....*.
gi 6707716 309 LVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPE 344
Cdd:PRK12436 261 GFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLERE 296
|
|
| murB |
PRK13904 |
UDP-N-acetylmuramate dehydrogenase; |
112-348 |
1.37e-11 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 184384 [Multi-domain] Cd Length: 257 Bit Score: 63.79 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 112 CVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTawdVKGGrWVEmgAAECRFAYRDSFFKHqepgawVIGS 191
Cdd:PRK13904 84 AKKNNLGGFEFLGKLPGTLGGLVKMNAGLKEYEISNNLESIC---TNGG-WIE--KEDIGFGYRSSGING------VILE 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 192 VRFALPRPWQPVLDypdlqrhaaldgaaptaravydAVCAIRRAKLPDPAvvgNAGSFFKNPlvdagtrqallgrfpglv 271
Cdd:PRK13904 152 ARFKKTHGFDEELL----------------------EAFKSMRKNQPKGP---SFGSCFKNP------------------ 188
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 6707716 272 sypqpDGRYklaAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVV 348
Cdd:PRK13904 189 -----KGDY---AGRLIEAVGLKGYCKGGAGFSEEHANFLVNLGGATFEDALDLIELAKKRVLEEFGINLEEEVIIL 257
|
|
| PRK14648 |
PRK14648 |
UDP-N-acetylmuramate dehydrogenase; |
43-344 |
2.55e-10 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173111 [Multi-domain] Cd Length: 354 Bit Score: 60.89 E-value: 2.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 43 SQLPALSALAPRFR-QLVVLGGGSNVVLP-ASIDGLVAQVR-LPGVRLVGQCADAWVVEAAAGENWHGFVTACVDNGWDG 119
Cdd:PRK14648 40 TQLRALIEEAQRARiPLSLIGGGSNVLIAdEGVPGLMLSLRrFRSLHTQTQRDGSVLVHAGAGLPVAALLAFCAHHALRG 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 120 LENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEMGAAECRFAYRDSFFK--HQEPGAWVIGSVR--FA 195
Cdd:PRK14648 120 LETFAGLPGSVGGAAYMNARCYGRAIADCFHSARTLVLHPVRSRAKELPEVRKNAQDKRGEclGLDGGPFTCSSFQtvFA 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 196 LPRPW----QPVLDYPDLQRHAaldgaaptARAVYDAVCAirRAKLPDPAVVGNagsFFKNPLVDAGTRQALlgRFPGLV 271
Cdd:PRK14648 200 RAGDWgykrSPFQSPHGVELHA--------GRRLILSLCV--RLTPGNPAQIRK---HMQEKIADRISKGQF--RFPSAG 264
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6707716 272 SYPQPDGRYKLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPE 344
Cdd:PRK14648 265 SAFKNNPAFGKPSGILIEEAGLRGTSCGAAQVAPWHGNLIINTGNATAHQVRTLLRVVRQRVFETHGVWLERE 337
|
|
| PRK14650 |
PRK14650 |
UDP-N-acetylmuramate dehydrogenase; |
57-344 |
2.64e-05 |
|
UDP-N-acetylmuramate dehydrogenase;
Pssm-ID: 173113 [Multi-domain] Cd Length: 302 Bit Score: 45.22 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 57 QLVVLGGGSNVVL--------PASIDGLVAQVRLPGVRLVGQCadawvveaaaGENWHGFVTACVDNGWDGLENLALIPG 128
Cdd:PRK14650 58 KIFILGGGSNILIndeeeidfPIIYTGHLNKIEIHDNQIVAEC----------GTNFEDLCKFALQNELSGLEFIYGLPG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 129 TVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEMGAAEcRFAYRDSFFKHQEpgaWVIGSVRFALPRPWQPVLDYPD 208
Cdd:PRK14650 128 TLGGAIWMNARCFGNEISEILDKITFIDEKGKTICKKFKKE-EFKYKISPFQNKN---TFILKATLNLKKGNKKHIEEIM 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6707716 209 LQRHAAldgaaptaravydavcAIRRAKLPDPAvvgnAGSFFKNPlvdagtrqallgrfpglVSYPQPDGRyklaagwLI 288
Cdd:PRK14650 204 KQNKQI----------------RINKGHYLFPS----SGSTFKNN-----------------KAFLKPTGQ-------II 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 6707716 289 DQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPE 344
Cdd:PRK14650 240 EECKLKGLSIGGATVSHYHGNFIININNATSKDIKTLIEKVKTEVQIKTGFLLEEE 295
|
|
| |
