|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
17-388 |
7.05e-96 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 291.59 E-value: 7.05e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 17 PVMAQIRSLMAELTNPMSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKL---TNSQVM 93
Cdd:PRK05957 14 PIIPVVGQLIRENPGTISLGQGVVSYPPPPEAIEALNNFLANPENHKYQAVQGIPPLLEAITQKLQQDNGIelnNEQAIV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 94 VTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDAdwLERTLSESkpTPKVVTvVN 173
Cdd:PRK05957 94 VTAGSNMAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDDNYQLQPEA--IEQAITPK--TRAIVT-IS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 174 PGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCV-----EGDHIVNVFSFSKTYGMMGWRLGYIAYS 248
Cdd:PRK05957 169 PNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFSPgsipgSGNHTISLYSLSKAYGFASWRIGYMVIP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 249 ERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKE-NVKGGEGAIYLWAKL 327
Cdd:PRK05957 249 IHL---LEAIKKIQDTILICPPVVSQYAALGALQVGKSYCQQHLPEIAQVRQILLKSLGQLQDRcTLHPANGAFYCFLKV 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75169651 328 PEGhRDDFKVVRWLAHRHGVVVIPGCASG--SPGYLRVSFGGLQEVEMRAAAARLRKGIEELL 388
Cdd:PRK05957 326 NTD-LNDFELVKQLIREYRVAVIPGTTFGmkNGCYLRIAYGALQKATAKEGIERLVQGLKTIV 387
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
16-387 |
1.65e-93 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 285.49 E-value: 1.65e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 16 MPVMAQIRSLMAELTNPMSLAQGVVHWQPPQKALEKVKELVwDPIISSYGPDEGLPELRQALLKKLREEN--KLTNSQVM 93
Cdd:COG0436 16 REVSALAAELKAAGEDVIDLGIGEPDFPTPDHIREAAIEAL-DDGVTGYTPSAGIPELREAIAAYYKRRYgvDLDPDEIL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 94 VTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWLERTLSeskPTPKVVTVVN 173
Cdd:COG0436 95 VTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENGFLPDPEALEAAIT---PRTKAIVLNS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 174 PGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCC---VEG--DHIVNVFSFSKTYGMMGWRLGYIAYS 248
Cdd:COG0436 172 PNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSilsLPGlkDRTIVINSFSKSYAMTGWRIGYAVGP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 249 ERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKgGEGAIYLWAKLP 328
Cdd:COG0436 252 PEL---IAALLKLQSNLTSCAPTPAQYAAAAALEGPQDYVEEMRAEYRRRRDLLVEGLNEIGLSVVK-PEGAFYLFADVP 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75169651 329 EGHRDDFKVVRWLAHRHGVVVIPGCA--SGSPGYLRVSFGGLQEVeMRAAAARLRKGIEEL 387
Cdd:COG0436 328 ELGLDSEEFAERLLEEAGVAVVPGSAfgPAGEGYVRISYATSEER-LEEALERLARFLERY 387
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
33-382 |
2.34e-90 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 276.14 E-value: 2.34e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 33 MSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREEN--KLTNSQVMVTAGANQAFVNLVITLC 110
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGgvDVPPEEIVVTNGAQEALSLLLRALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 111 DAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWLERtlsESKPTPKVVTVVNPGNPSGTYVPEPLLKRI 190
Cdd:cd00609 81 NPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLEA---AKTPKTKLLYLNNPNNPTGAVLSEEELEEL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 191 AQICKDAGCWLIVDNTYEYFMYDGLKHCCVE----GDHIVNVFSFSKTYGMMGWRLGYIAYSERLdgFATELVKIQDNIP 266
Cdd:cd00609 158 AELAKKHGILIISDEAYAELVYDGEPPPALAlldaYERVIVLRSFSKTFGLPGLRIGYLIAPPEE--LLERLKKLLPYTT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 267 ICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGhrDDFKVVRWLAHRHG 346
Cdd:cd00609 236 SGPSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVKPSGGFFLWLDLPEG--DDEEFLERLLLEAG 313
|
330 340 350
....*....|....*....|....*....|....*...
gi 75169651 347 VVVIPGCASGS--PGYLRVSFGGLQEvEMRAAAARLRK 382
Cdd:cd00609 314 VVVRPGSAFGEggEGFVRLSFATPEE-ELEEALERLAE 350
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
6-381 |
1.75e-71 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 228.69 E-value: 1.75e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 6 MLSRRTLGTDMPVMAQIRSLMAELTNP----MSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKL 81
Cdd:PRK07550 1 PLNPLIAALFPPPIPEVRAWLAGYDGAdgplIDLSQAVPGYPPPPELLRALAEAAADPAAHLYGPVEGLPELREAYAAHY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 82 RE--ENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWLERTL 159
Cdd:PRK07550 81 SRlyGAAISPEQVHITSGCNQAFWAAMVTLAGAGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGPGLLPDPAAAEALI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 160 sesKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYD-GLKHCCVE----GDHIVNVFSFSKT 234
Cdd:PRK07550 161 ---TPRTRAIALVTPNNPTGVVYPPELLHELYDLARRHGIALILDETYRDFDSGgGAPHDLFAdpdwDDTLVHLYSFSKS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 235 YGMMGWRLGYIAYSErldGFATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENV 314
Cdd:PRK07550 238 YALTGHRVGAVVASP---ARIAEIEKFMDTVAICAPRIGQIAVAWGLPNLADWRAGNRAEIARRRDAFRAVFARLPGWEL 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 315 kGGEGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASGsPG---YLRVSFGGLQEVEMRAAAARLR 381
Cdd:PRK07550 315 -LASGAYFAYVRHPFPDRPSREVARRLAKEAGILCLPGTMFG-PGqegYLRLAFANADVAGIGELVERLR 382
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
64-388 |
2.61e-62 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 205.36 E-value: 2.61e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKLREENKLT--NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFnSYMAF-QMTGVTNIIV 140
Cdd:PRK05764 64 YTPAAGIPELREAIAAKLKRDNGLDydPSQVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWV-SYPEMvKLAGGVPVFV 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 141 GPGQSDTLYPDADWLERTLSEskPTpKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHC-- 218
Cdd:PRK05764 143 PTGEENGFKLTVEQLEAAITP--KT-KALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTsi 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 219 --CVEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKS 294
Cdd:PRK05764 220 asLSPElrDRTITVNGFSKAYAMTGWRLGYAAGPKEL---IKAMSKLQSHSTSNPTSIAQYAAVAALNGPQDEVEEMRQA 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 295 LVKNRDIVKEALEPLGKENVKGGEGAIYLWAK----LPEGHRDDFKVVRWLAHRHGVVVIPGCASGSPGYLRVSFGGLQE 370
Cdd:PRK05764 297 FEERRDLMVDGLNEIPGLECPKPEGAFYVFPNvsklLGKSITDSLEFAEALLEEAGVAVVPGIAFGAPGYVRLSYATSLE 376
|
330
....*....|....*...
gi 75169651 371 vEMRAAAARLRKGIEELL 388
Cdd:PRK05764 377 -DLEEGLERIERFLESLK 393
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
30-380 |
9.56e-55 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 184.43 E-value: 9.56e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 30 TNPMSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLV 106
Cdd:pfam00155 1 TDKINLGSNEYLGDTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKldrEAAVVFGSGAGANIEALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 107 ITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWLERTLSESkptPKVVTVVNPGNPSGTYVPEPL 186
Cdd:pfam00155 81 FLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEK---PKVVLHTSPHNPTGTVATLEE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 187 LKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCV-----EGDHIVNVFSFSKTYGMMGWRLGYIAYSERLdgfATELVKI 261
Cdd:pfam00155 158 LEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATrallaEGPNLLVVGSFSKAFGLAGWRVGYILGNAAV---ISQLRKL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 262 QDniPICAAIISQRLAVYAL---EEGSGWITERVKSLVKNRDIVKEALEPLGKeNVKGGEGAIYLWAKL-PEGHRDDFKV 337
Cdd:pfam00155 235 AR--PFYSSTHLQAAAAAALsdpLLVASELEEMRQRIKERRDYLRDGLQAAGL-SVLPSQAGFFLLTGLdPETAKELAQV 311
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 75169651 338 vrwLAHRHGVVVIPGCASGSPGYLRVSFGGLQEVEMRAAAARL 380
Cdd:pfam00155 312 ---LLEEVGVYVTPGSSPGVPGWLRITVAGGTEEELEELLEAI 351
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
58-388 |
1.71e-40 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 149.21 E-value: 1.71e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 58 DPIISSYGPDEGLPELRQALLKKLREEN-KLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVT 136
Cdd:COG1167 138 PPALLGYGDPQGLPELREAIARYLARRGvPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 137 niIVG-PGQSDTLYPDAdwLERTLSESKptPKVVtVVNPG--NPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYD 213
Cdd:COG1167 218 --LVPvPVDEDGLDLDA--LEAALRRHR--PRAV-YVTPShqNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYD 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 214 G-----LKhCCVEGDHIVNVFSFSKTygMM-GWRLGYIAYSERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGsGW 287
Cdd:COG1167 291 GrppppLA-ALDAPGRVIYIGSFSKT--LApGLRLGYLVAPGRL---IERLARLKRATDLGTSPLTQLALAEFLESG-HY 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 288 ---ITERVKSLVKNRDIVKEALEPLGKENVK--GGEGAIYLWAKLPEGhRDDFKVVRwLAHRHGVVVIPG---CASGSP- 358
Cdd:COG1167 364 drhLRRLRREYRARRDLLLAALARHLPDGLRvtGPPGGLHLWLELPEG-VDAEALAA-AALARGILVAPGsafSADGPPr 441
|
330 340 350
....*....|....*....|....*....|
gi 75169651 359 GYLRVSFGGLQEVEMRAAAARLRKGIEELL 388
Cdd:COG1167 442 NGLRLGFGAPSEEELEEALRRLAELLRELA 471
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
20-387 |
3.90e-39 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 144.25 E-value: 3.90e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 20 AQIRSLM---AELTNPMSLAQGVVHWQPPQKALEKVKELVwDPIISSYGPDEGLPELRQALLKKLREENKLTNS--QVMV 94
Cdd:PRK08361 20 SKIRELFeraSKMENVISLGIGEPDFDTPKNIKEAAKRAL-DEGWTHYTPNAGIPELREAIAEYYKKFYGVDVDvdNVIV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 95 TAGANQAFVNLVITLCDAGDSVVMFEPYyFNSYMAFQMTGVTNIIVGP-GQSDTLYPDADWLERTLSESKptpKVVTVVN 173
Cdd:PRK08361 99 TAGAYEATYLAFESLLEEGDEVIIPDPA-FVCYVEDAKIAEAKPIRIPlREENEFQPDPDELLELITKRT---RMIVINY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 174 PGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCV---EGDHIVNVFSFSKTYGMMGWRLGYIAYSER 250
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMikyAPDNTILANSFSKTFAMTGWRLGFVIAPEQ 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 251 LdgfatelvkIQDNIPICAAIIS------QRLAVYALEEGSGW--ITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIY 322
Cdd:PRK08361 255 V---------IKDMIKLHAYIIGnvasfvQIAGIEALRSKESWkaVEEMRKEYNERRKLVLKRLKEMPHIKVFEPKGAFY 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75169651 323 LWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASG--SPGYLRVSFGGLQEvEMRAAAARLRKGIEEL 387
Cdd:PRK08361 326 VFANIDETGMSSEDFAEWLLEKARVVVIPGTAFGkaGEGYIRISYATSKE-KLIEAMERMEKALEEL 391
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
50-386 |
4.52e-38 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 141.01 E-value: 4.52e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 50 EKVKELVWDPI---ISSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY 123
Cdd:PRK07309 46 DHVKEAAKRAIdanQSHYTGMAGLLELRQAAADFVKEKYNLDyapENEILVTIGATEALSASLTAILEPGDKVLLPAPAY 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 124 FNSYMAFQMTGVTNIIVGPGQSD-TLYPDAdwLERTLSESKPTPKVVTVVNPGNPSG-TYVPEPlLKRIAQICKDAGCWL 201
Cdd:PRK07309 126 PGYEPIVNLVGAEIVEIDTTENDfVLTPEM--LEKAILEQGDKLKAVILNYPANPTGvTYSREQ-IKALADVLKKYDIFV 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 202 IVDNTYEYFMYDGLKHCCVEG---DHIVNVFSFSKTYGMMGWRLGYIAYSERldgFATELVKIQDNIPICAAIISQRLAV 278
Cdd:PRK07309 203 ISDEVYSELTYTGEPHVSIAEylpDQTILINGLSKSHAMTGWRIGLIFAPAE---FTAQLIKSHQYLVTAATTMAQFAAV 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 279 YALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKgGEGAIYLWAKLPEG-HRDDFKVVRWLAHRHGVVVIPGCASG- 356
Cdd:PRK07309 280 EALTNGKDDALPMKKEYIKRRDYIIEKMTDLGFKIIK-PDGAFYIFAKIPAGyNQDSFKFLQDFARKKAVAFIPGAAFGp 358
|
330 340 350
....*....|....*....|....*....|.
gi 75169651 357 -SPGYLRVSFGGLQEVeMRAAAARLRKGIEE 386
Cdd:PRK07309 359 yGEGYVRLSYAASMET-IKEAMKRLKEYMEE 388
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
64-385 |
2.93e-34 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 130.45 E-value: 2.93e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKL--REENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVG 141
Cdd:PRK06108 57 YTHNLGIPELREALARYVsrLHGVATPPERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVP 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 142 PGqsdtlYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGlkHC 218
Cdd:PRK06108 137 LD-----FGGGGWtldLDRLLAAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAP--GG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 219 CV--------EGDHIVNVFSFSKTYGMMGWRLGYIAYSERLDGFATELvkIQDNIPiCAAIISQRLAVYALEEGSGWITE 290
Cdd:PRK06108 210 RApsfldiaePDDRIIFVNSFSKNWAMTGWRLGWLVAPPALGQVLEKL--IEYNTS-CVAQFVQRAAVAALDEGEDFVAE 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 291 RVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPeGHRDDFKVVRWLAHRHGVVVIPGCASGSPG--YLRVSFggL 368
Cdd:PRK06108 287 LVARLRRSRDHLVDALRALPGVEVAKPDGAMYAFFRIP-GVTDSLALAKRLVDEAGLGLAPGTAFGPGGegFLRWCF--A 363
|
330
....*....|....*...
gi 75169651 369 QEVE-MRAAAARLRKGIE 385
Cdd:PRK06108 364 RDPArLDEAVERLRRFLA 381
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
44-365 |
8.64e-34 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 129.54 E-value: 8.64e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVW--DPIISSYGPDEGLPELRQALLKKLREE--NKLTNSQVMVTAGANQAfVNLVI-TLCDAGDSVVM 118
Cdd:PRK06836 47 PPAAVKEALRELAEeeDPGLHGYMPNAGYPEVREAIAESLNRRfgTPLTADHIVMTCGAAGA-LNVALkAILNPGDEVIV 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 119 FEPYyFNSYMAF-QMTGVTNIIVgPGQSDTLYPDADWLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDA 197
Cdd:PRK06836 126 FAPY-FVEYRFYvDNHGGKLVVV-PTDTDTFQPDLDALEAAIT---PKTKAVIINSPNNPTGVVYSEETLKALAALLEEK 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 198 G------CWLIVDNTYEYFMYDGLKHCCVEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLDGFAtELVK--IQDNIP- 266
Cdd:PRK06836 201 SkeygrpIYLISDEPYREIVYDGAEVPYIFKyyDNSIVVYSFSKSLSLPGERIGYIAVNPEMEDAD-DLVAalVFANRIl 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 267 --ICAAIISQRLAVYALEEgsgwiTERVKSLVKNRDIVKEALEPLGKENVKgGEGAIYLWAKLPEGhrDDFKVVRwLAHR 344
Cdd:PRK06836 280 gfVNAPALMQRVVAKCLDA-----TVDVSIYKRNRDLLYDGLTELGFECVK-PQGAFYLFPKSPEE--DDVAFCE-KAKK 350
|
330 340
....*....|....*....|.
gi 75169651 345 HGVVVIPGCASGSPGYLRVSF 365
Cdd:PRK06836 351 HNLLLVPGSGFGCPGYFRLSY 371
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
42-388 |
1.59e-33 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 129.16 E-value: 1.59e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 42 WQPPqkalEKVKELVWDPIISS---YGPDEGLPELRQALLKKLREEN--KLTNSQVMVTAGANQAFVNLVITLCDAGDSV 116
Cdd:PRK08363 45 FQPP----EHMKEAYCRAIKEGhnyYGPSEGLPELREAIVKREKRKNgvDITPDDVRVTAAVTEALQLIFGALLDPGDEI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 117 VMFEPYY--FNSYMAFQmTGVtniivgPGQSDTL-----YPDADWLERTLSESKptpKVVTVVNPGNPSGTYVPEPLLKR 189
Cdd:PRK08363 121 LIPGPSYppYTGLVKFY-GGV------PVEYRTIeeegwQPDIDDIRKKITEKT---KAIAVINPNNPTGALYEKKTLKE 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 190 IAQICKDAGCWLIVDNTYEYFMYDGlKHC---CVEGDHIVNVFS-FSKTYGMMGWRLGYIAY---SERLDGFATELVKIQ 262
Cdd:PRK08363 191 ILDIAGEHDLPVISDEIYDLMTYEG-KHVspgSLTKDVPVIVMNgLSKVYFATGWRLGYIYFvdpEGKLAEVREAIDKLA 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 263 dNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRD-IVKEALEPLGKENVKgGEGAIYLWAKLPEGH-RDDFKVVRW 340
Cdd:PRK08363 270 -RIRLCPNTPAQFAAIAGLTGPMDYLEEYMKKLKERRDyIYKRLNEIPGISTTK-PQGAFYIFPRIEEGPwKDDKEFVLD 347
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 75169651 341 LAHRHGVVVIPGCASGSPG--YLRVSFggLQEVE-MRAAAARLRKGIEELL 388
Cdd:PRK08363 348 VLHEAHVLFVHGSGFGEYGagHFRLVF--LPPVEiLEEAMDRFEEFMRERL 396
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
43-386 |
2.38e-33 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 128.43 E-value: 2.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 43 QP----PQKALEKVKELvwDPIISSYGPDEGLPELRQALLKKLREEN-KLTNSQVMVTAGANQAFVNLVITLCDAGDSVV 117
Cdd:PRK07568 39 QPdiktPEVFFEAIKNY--DEEVLAYSHSQGIPELREAFAKYYKKWGiDVEPDEILITNGGSEAILFAMMAICDPGDEIL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 118 MFEPYYFNsYMAF-QMTGVtNIIVGPGQSDTLY--PDADWLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQIC 194
Cdd:PRK07568 117 VPEPFYAN-YNGFaTSAGV-KIVPVTTKIEEGFhlPSKEEIEKLIT---PKTKAILISNPGNPTGVVYTKEELEMLAEIA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 195 KDAGCWLIVDNTYEYFMYDGLKH---CCVEG--DHIVNVFSFSKTYGMMGWRLGYIAysERLDGFATELVKI-QDNipIC 268
Cdd:PRK07568 192 KKHDLFLISDEVYREFVYDGLKYtsaLSLEGleDRVIIIDSVSKRYSACGARIGCLI--SKNKELIAAAMKLcQAR--LS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 269 AAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGHRDDFkvVRWLA---HRH 345
Cdd:PRK07568 268 PPTLEQIGAAALLDTPESYFDEVREEYKKRRDILYEELNKIPGVVCEKPKGAFYIIAKLPVDDAEDF--AKWLLtdfNYN 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 75169651 346 G--VVVIPgcASG---SPGY----LRVSFgGLQEVEMRAAAARLRKGIEE 386
Cdd:PRK07568 346 GetVMVAP--ASGfyaTPGLgkneIRIAY-VLNEEDLKRAMEILKEALEK 392
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
24-382 |
2.57e-33 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 128.23 E-value: 2.57e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 24 SLMAELTNPMSLAQGVVHWQPPQKALEKVKELVWDPIiSSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQ 100
Cdd:PRK07777 18 SALAVRTGAVNLGQGFPDEDGPPEMLEAAQEAIAGGV-NQYPPGPGIPELRAAIAAQRRRRYGLEydpDTEVLVTVGATE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 101 AFVNLVITLCDAGDSVVMFEPYYfNSYMA-FQMTGVTNIIVGPGQSDTLY-PDADWLERTLSeskPTPKVVTVVNPGNPS 178
Cdd:PRK07777 97 AIAAAVLGLVEPGDEVLLIEPYY-DSYAAvIAMAGAHRVPVPLVPDGRGFaLDLDALRAAVT---PRTRALIVNSPHNPT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 179 GTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVEG-----DHIVNVFSFSKTYGMMGWRLGYIAYSERLdg 253
Cdd:PRK07777 173 GTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATlpgmrERTVTISSAAKTFNVTGWKIGWACGPAPL-- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 254 fATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEGAIYLWAKL-PEGHR 332
Cdd:PRK07777 251 -IAAVRAAKQYLTYVGGAPFQPAVAHALDHEDAWVAALRDSLQAKRDRLAAGLAEAGFE-VHDSAGTYFLCADPrPLGYD 328
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 75169651 333 DDFKVVRWLAHRHGVVVIPGCA------SGSPgYLRVSFGGLQEVeMRAAAARLRK 382
Cdd:PRK07777 329 DGTEFCRALPERVGVAAIPMSVfydpadAWNH-LVRFAFCKRDDT-LDEAIRRLRA 382
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
27-382 |
7.88e-33 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 125.63 E-value: 7.88e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 27 AELTNPMSLAQGVVHWQPPQKALEKVKELVWDpiISSYgPDEGLPELRQALLKKLReenkLTNSQVMVTAGANQAFVNLV 106
Cdd:COG0079 10 EEPEDIIKLSSNENPYGPPPKVLEAIAAALDA--LNRY-PDPDATALREALAEYYG----VPPEQVLVGNGSDELIQLLA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 107 ITLCDAGDSVVMFEPyyfnSY----MAFQMTGVTnIIVGPgqsdtlyPDADW---LERTLSESKPTPKVVTVVNPGNPSG 179
Cdd:COG0079 83 RAFLGPGDEVLVPEP----TFseypIAARAAGAE-VVEVP-------LDEDFsldLDALLAAITERTDLVFLCNPNNPTG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 180 TYVPEPLLKRIAQICkDAGCWLIVDntyE-YFMYDGLKHCCV----EGDHIVnVF-SFSKTYGMMGWRLGYIAYSERLdg 253
Cdd:COG0079 151 TLLPREELEALLEAL-PADGLVVVD---EaYAEFVPEEDSALpllaRYPNLV-VLrTFSKAYGLAGLRLGYAIASPEL-- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 254 fATELVKIQD--NIPicaaIISQRLAVYALEEgSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEgAIYLWAKLPEGH 331
Cdd:COG0079 224 -IAALRRVRGpwNVN----SLAQAAALAALED-RAYLEETRARLRAERERLAAALRALGLT-VYPSQ-ANFVLVRVPEDA 295
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 75169651 332 RDdfkVVRWLAhRHGVVVIPGCASGSPGYLRVSFGGlqEVEMRAAAARLRK 382
Cdd:COG0079 296 AE---LFEALL-ERGILVRDFSSFGLPDYLRITVGT--PEENDRLLAALKE 340
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
64-384 |
1.74e-32 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 125.94 E-value: 1.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKLREENKLT--NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY-FNSYMAFQMTGVT-NII 139
Cdd:PRK08960 65 YTAARGLPALREAIAGFYAQRYGVDvdPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYpCNRHFLRLVEGAAqLVP 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 140 VGPGQSDTLYP---DADWLERTLSeskptpkvVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLK 216
Cdd:PRK08960 145 VGPDSRYQLTPalvERHWNADTVG--------ALVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVDA 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 217 HCCVE-GDHIVNVFSFSKTYGMMGWRLGYIAYSErldGFATELVKIQDNIPICAAIISQRLAVYALEEGSGWITE-RVKS 294
Cdd:PRK08960 217 ASVLEvDDDAFVLNSFSKYFGMTGWRLGWLVAPP---AAVPELEKLAQNLYISASTPAQHAALACFEPETLAILEaRRAE 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 295 LVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASGS--PG-YLRVSFggLQEV 371
Cdd:PRK08960 294 FARRRDFLLPALRELGFGIAVEPQGAFYLYADISAFGGDAFAFCRHFLETEHVAFTPGLDFGRhqAGqHVRFAY--TQSL 371
|
330
....*....|....
gi 75169651 372 E-MRAAAARLRKGI 384
Cdd:PRK08960 372 PrLQEAVERIARGL 385
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
64-387 |
1.84e-32 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 126.00 E-value: 1.84e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKLREENKL--TNSQVMVTAGANQA-FVNLVITLcDAGDSVVMFEPYYFnSY--MAFQMTGvTNI 138
Cdd:PRK06107 66 YTLVNGTPALRKAIIAKLERRNGLhyADNEITVGGGAKQAiFLALMATL-EAGDEVIIPAPYWV-SYpdMVLANDG-TPV 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 139 IVGPGQSDTLYPDADWLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKD-AGCWLIVDNTYEYFMYDG--- 214
Cdd:PRK06107 143 IVACPEEQGFKLTPEALEAAIT---PRTRWLILNAPSNPTGAVYSRAELRALADVLLRhPHVLVLTDDIYDHIRFDDept 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 215 ---------LKhccvegDHIVNVFSFSKTYGMMGWRLGYIAYSERLDGfatELVKIQDNIPICAAIISQRLAVYALEEGS 285
Cdd:PRK06107 220 phllaaapeLR------DRVLVTNGVSKTYAMTGWRIGYAAGPADLIA---AINKLQSQSSSCPSSISQAAAAAALNGDQ 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 286 GWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWA--------KLPEGHR--DDFKVVRWLAHRHGVVVIPGCAS 355
Cdd:PRK06107 291 SFVTESVAVYKQRRDYALALLNAIPGLSCLVPDGAFYLYVncagligkTTPEGKVleTDQDVVLYLLDSAGVAVVQGTAY 370
|
330 340 350
....*....|....*....|....*....|..
gi 75169651 356 GSPGYLRVSFGGLQEVeMRAAAARLRKGIEEL 387
Cdd:PRK06107 371 GLSPYFRLSIATSLET-LEEACARIERAVAAL 401
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
61-382 |
6.69e-31 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 121.70 E-value: 6.69e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 61 ISSYGPDEGLPELRQALLKKLREENKLT--NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY-FNSYMAFQMTGVTN 137
Cdd:PRK07337 60 VTQYTSALGLAPLREAIAAWYARRFGLDvaPERIVVTAGASAALLLACLALVERGDEVLMPDPSYpCNRHFVAAAEGRPV 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 138 II-VGPGQSDTLYPD---ADWLERTlseskptpKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYD 213
Cdd:PRK07337 140 LVpSGPAERFQLTAAdveAAWGERT--------RGVLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYD 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 214 GLKHCCVE-GDHIVNVFSFSKTYGMMGWRLGYIAYSERLDGfatELVKIQDNIPICAAIISQRLAVYALEEGSGWITERV 292
Cdd:PRK07337 212 AAPVSALSlGDDVITINSFSKYFNMTGWRLGWLVVPEALVG---TFEKLAQNLFICASALAQHAALACFEPDTLAIYERR 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 293 KSLVK-NRDIVKEALEPLGKENVKGGEGAIYLWAKLPE-GHR---DDFKVVRWLAHRHGVVVIPGCASGSPG---YLRVS 364
Cdd:PRK07337 289 RAEFKrRRDFIVPALESLGFKVPVMPDGAFYVYADCRGvAHPaagDSAALTQAMLHDAGVVLVPGRDFGPHAprdYIRLS 368
|
330
....*....|....*....
gi 75169651 365 FG-GLQEVEmrAAAARLRK 382
Cdd:PRK07337 369 YAtSMSRLE--EAVARLGK 385
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
63-387 |
2.88e-29 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 116.58 E-value: 2.88e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 63 SYGPDEGLPELRQA---LLKKLREENkltnsqVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNII 139
Cdd:PRK07324 57 TYGWIEGSPEFKEAvasLYQNVKPEN------ILQTNGATGANFLVLYALVEPGDHVISVYPTYQQLYDIPESLGAEVDY 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 140 VGPGQSDTLYPDADWLERTLsesKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGlkhcc 219
Cdd:PRK07324 131 WQLKEENGWLPDLDELRRLV---RPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDG----- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 220 vEGDHIVNVF-------SFSKTYGMMGWRLGYIAYSERLdgfATELVKIQDNIPICAAIISQRLAVYALEegsgwitERV 292
Cdd:PRK07324 203 -STPSIADLYekgistnSMSKTYSLPGIRVGWIAANEEV---IDILRKYRDYTMICAGVFDDMLASLALE-------HRD 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 293 KSLVKNRDIVKEAL---------EPLgKENVKGGEGAI-YLWAKLPEghrDDFKVVRWLAHRHGVVVIPGCASGSPGYLR 362
Cdd:PRK07324 272 AILERNRKIVRTNLaildewvakEPR-VSYVKPKAVSTsFVKLDVDM---PSEDFCLKLLKETGVLLVPGNRFDLEGHVR 347
|
330 340
....*....|....*....|....*
gi 75169651 363 VSFGGLQEVemraaaarLRKGIEEL 387
Cdd:PRK07324 348 IGYCCDTET--------LKKGLKKL 364
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
64-387 |
4.52e-28 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 113.53 E-value: 4.52e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYfNSYMAF-QMTGVTNII 139
Cdd:PRK08912 59 YPPMMGLPELRQAVAAHYARFQGLDldpETEVMVTSGATEALAAALLALVEPGDEVVLFQPLY-DAYLPLiRRAGGVPRL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 140 VgpgqsdTLYPdADW-LERTLSESKPTP--KVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLK 216
Cdd:PRK08912 138 V------RLEP-PHWrLPRAALAAAFSPrtKAVLLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRR 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 217 H---CCVEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGSGWITER 291
Cdd:PRK08912 211 HiplMTLPGmrERTVKIGSAGKIFSLTGWKVGFVCAAPPL---LRVLAKAHQFLTFTTPPNLQAAVAYGLGKPDDYFEGM 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 292 VKSLVKNRDIVKEALEPLGKEnVKGGEGAIYLWAKL-PEGH-RDDFKVVRWLAHRHGVVVIPGCA---SGSP-GYLRVSF 365
Cdd:PRK08912 288 RADLARSRDRLAAGLRRIGFP-VLPSQGTYFLTVDLaPLGLaEDDVAFCRRLVEEAGVAAIPVSAfyeEDPVtSVVRFCF 366
|
330 340
....*....|....*....|..
gi 75169651 366 GGLQEVeMRAAAARLRKGIEEL 387
Cdd:PRK08912 367 AKRDAT-LDEAVERLAAARRRR 387
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
45-387 |
6.78e-28 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 113.26 E-value: 6.78e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 45 PQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEP 121
Cdd:PRK08636 48 PQHIIDKLCESAQKPKTHGYSVSKGIYKLRLAICNWYKRKYNVDldpETEVVATMGSKEGYVHLVQAITNPGDVAIVPDP 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 122 YYFNSYMAFQMTG--VTNIIVGPGQSDTLYPDADW--LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDA 197
Cdd:PRK08636 128 AYPIHSQAFILAGgnVHKMPLEYNEDFELDEDQFFenLEKALRESSPKPKYVVVNFPHNPTTATVEKSFYERLVALAKKE 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 198 GCWLIVDNTYEYFMYDGLKHCC---VEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLDGfatELVKIQDNI------P 266
Cdd:PRK08636 208 RFYIISDIAYADITFDGYKTPSileVEGakDVAVESYTLSKSYNMAGWRVGFVVGNKKLVG---ALKKIKSWLdygmftP 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 267 IcaaiisQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKgGEGAIYLWAKLPE--GHRDDFKVVRWLAHR 344
Cdd:PRK08636 285 I------QVAATIALDGDQSCVEEIRETYRKRRDVLIESFANAGWELQK-PRASMFVWAKIPEpaRHLGSLEFSKQLLTE 357
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 75169651 345 HGVVVIPGCASGSPG--YLRVSfggLQEVE--MRAAAARLRKGIEEL 387
Cdd:PRK08636 358 AKVAVSPGIGFGEYGdeYVRIA---LIENEnrIRQAARNIKKFLKEL 401
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
64-364 |
9.40e-28 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 112.89 E-value: 9.40e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 64 YGPDEGLPELRQALLKKLREENKLT--NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYyFNSYM-AFQMTGVTNIIV 140
Cdd:PRK06348 62 YTDSGGDVELIEEIIKYYSKNYDLSfkRNEIMATVGACHGMYLALQSILDPGDEVIIHEPY-FTPYKdQIEMVGGKPIIL 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 141 GPGQSDTLYPDADWLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMY-------- 212
Cdd:PRK06348 141 ETYEEDGFQINVKKLEALIT---SKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFyedfvpma 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 213 --DGLKhccvegDHIVNVFSFSKTYGMMGWRLGYIAYSErldgFATELVK-IQDNIPICAAIISQRLAVYALEEGSGWIT 289
Cdd:PRK06348 218 tlAGMP------ERTITFGSFSKDFAMTGWRIGYVIAPD----YIIETAKiINEGICFSAPTISQRAAIYALKHRDTIVP 287
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75169651 290 ERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASGSPG--YLRVS 364
Cdd:PRK06348 288 LIKEEFQKRLEYAYKRIESIPNLSLHPPKGSIYAFINIKKTGLSSVEFCEKLLKEAHVLVIPGKAFGESGegYIRLA 364
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
44-381 |
1.28e-27 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 112.82 E-value: 1.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLRE--ENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEP 121
Cdd:TIGR01265 49 TDPEAEEAVKDALRSGKFNGYAPSVGALAAREAVAEYLSSdlPGKLTADDVVLTSGCSQAIEICIEALANPGANILVPRP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 122 YYFNSYMAFQMTGvtnIIVGPGQsdtLYPDADW---LE--RTLSESKPTPKVVTvvNPGNPSGTYVPEPLLKRIAQICKD 196
Cdd:TIGR01265 129 GFPLYDTRAAFSG---LEVRLYD---LLPEKDWeidLDglESLADEKTVAIVVI--NPSNPCGSVFSRDHLQKIAEVAEK 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 197 AGCWLIVDNTYEYFMYDGLKHCCV-EGDHIVNVFS---FSKTYGMMGWRLGYIAYSERLDGFATE----LVKIQDNIPIC 268
Cdd:TIGR01265 201 LGIPIIADEIYGHMVFGDAPFIPMaSFASIVPVLSlggISKRWVVPGWRLGWIIIHDPHGIFRDTvlqgLKNLLQRILGP 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 269 AAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKL-----PEGHrDDFKVVRWLAH 343
Cdd:TIGR01265 281 ATIVQGALPDILENTPQEFFDGKISVLKSNAELCYEELKDIPGLVCPKPEGAMYLMVKLelelfPEIK-DDVDFCEKLAR 359
|
330 340 350
....*....|....*....|....*....|....*...
gi 75169651 344 RHGVVVIPGCASGSPGYLRVSFgGLQEVEMRAAAARLR 381
Cdd:TIGR01265 360 EESVICLPGSAFGLPNWVRITI-TVPESMLEEACSRIK 396
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
33-307 |
6.56e-27 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 110.23 E-value: 6.56e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 33 MSLAQGVVHWQPPqkalEKVKELVWDPIIS----SYGPDEGLPELRQALLKKLreenKLTNSQVMVTAGANQAFVNLVIT 108
Cdd:PRK06225 31 IWMGQNTNHLGPH----EEVREAMIRCIEEgeycKYPPPEGFPELRELILKDL----GLDDDEALITAGATESLYLVMRA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 109 LCDAGDSVVMFEPYYF--NSYMAFQMTGVTNI-IVGPGQSDTLYPDA---DWLERTlseskptpKVVTVVNPGNPSGTYV 182
Cdd:PRK06225 103 FLSPGDNAVTPDPGYLiiDNFASRFGAEVIEVpIYSEECNYKLTPELvkeNMDENT--------RLIYLIDPLNPLGSSY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 183 PEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVEGDHIVNVFSFSKTYGMMGWRLG-YIAYSERLDgfATELVKI 261
Cdd:PRK06225 175 TEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYAPEHTVTSYSFSKIFGMAGLRIGaVVATPDLIE--VVKSIVI 252
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 75169651 262 QDnipICAAIISQRLAVYALEEGSGWItERVKSLV-KNRDIVKEALE 307
Cdd:PRK06225 253 ND---LGTNVIAQEAAIAGLKVKDEWI-DRIRRTTfKNQKLIKEAVD 295
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
21-386 |
2.60e-26 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 108.66 E-value: 2.60e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 21 QIRSLMAELTNPMSLAQGvvhwQPPQKALEKVKELVWDPI---ISSYGPDEGLPELRQALLKKLREENKL---TNSQVMV 94
Cdd:PRK07683 19 QFSNMVQNYDNLISLTIG----QPDFPTPSHVKEAAKRAItenYTSYTHNAGLLELRKAACNFVKDKYDLhysPESEIIV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 95 TAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVgpgqsDTLYPD----ADWLERTLSESKptpKVVT 170
Cdd:PRK07683 95 TIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFI-----DTRSTGfrltAEALENAITEKT---RCVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 171 VVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGlKHCCVEG-----DHIVNVFSFSKTYGMMGWRLGYI 245
Cdd:PRK07683 167 LPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHfpemrEKTIVINGLSKSHSMTGWRIGFL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 246 AYSERLdgfATELVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKgGEGAIYLWA 325
Cdd:PRK07683 246 FAPSYL---AKHILKVHQYNVTCASSISQYAALEALTAGKDDAKMMRHQYKKRRDYVYNRLISMGLDVEK-PTGAFYLFP 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75169651 326 KLPEGHRDDFKVVRWLAHRHGVVVIPGCASGS--PGYLRVSFgGLQEVEMRAAAARLRKGIEE 386
Cdd:PRK07683 322 SIGHFTMSSFDFALDLVEEAGLAVVPGSAFSEygEGYVRLSY-AYSIETLKEGLDRLEAFLQQ 383
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
44-382 |
6.08e-26 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 107.84 E-value: 6.08e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPIISSYGPDEGLPELRQALLK--------KLREEnkltnSQVMVTAGANQAFVNLVITLCDAGDS 115
Cdd:PRK09148 44 TPQHIVDKLCETAQDPRTHRYSASKGIPGLRRAQAAyyarrfgvKLNPD-----TQVVATLGSKEGFANMAQAITAPGDV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 116 VVMFEPYYFNSYMAFQMTGVTnIIVGPGQSDTLYPDAdwLERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICK 195
Cdd:PRK09148 119 ILCPNPSYPIHAFGFIMAGGV-IRSVPAEPDEEFFPA--LERAVRHSIPKPIALIVNYPSNPTAYVADLDFYKDVVAFAK 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 196 DAGCWLIVDNTYEYFMYDG------LKhccVEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLDGFATELVKIQDN--- 264
Cdd:PRK09148 196 KHDIIILSDLAYSEIYFDGnpppsvLQ---VPGakDVTVEFTSMSKTFSMAGWRMGFAVGNERLIAALTRVKSYLDYgaf 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 265 IPICAAiisqrlAVYALeEGSGWITERVKSLVKN-RDIVKEALEPLGKEnVKGGEGAIYLWAKLPEGHRD----DFKvvR 339
Cdd:PRK09148 273 TPIQVA------ATAAL-NGPQDCIAEMRELYKKrRDVLVESFGRAGWD-IPPPAASMFAWAPIPEAFRHlgslEFS--K 342
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 75169651 340 WLAHRHGVVVIPGCASGSPG--YLRVsfgGLQEVE--MRAAAARLRK 382
Cdd:PRK09148 343 LLVEKADVAVAPGVGFGEHGdgYVRI---ALVENEqrIRQAARNIKR 386
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
43-378 |
1.08e-24 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 104.41 E-value: 1.08e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 43 QP-PQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVM 118
Cdd:PRK08175 41 GPtPPHIVEKLCEVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVDidpESEAIVTIGSKEGLAHLMLATLDHGDTVLV 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 119 FEPYY-FNSYMAfqmtgvtnIIVGPG-QSDTLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQI 193
Cdd:PRK08175 121 PNPSYpIHIYGA--------VIAGAQvRSVPLVEGVDFfneLERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVAL 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 194 CKDAGCWLIVDNTYEYFMYDGLKHCC---VEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLdgfATELVKIQDNI--- 265
Cdd:PRK08175 193 AKRYDVLVVHDLAYADIVYDGWKAPSimqVPGakDVAVEFFTLSKSYNMAGWRIGFMVGNPEL---VSALARIKSYHdyg 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 266 ---PIcaaiisQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEGAIYLWAKLPEGHRD--DFKVVRW 340
Cdd:PRK08175 270 tftPL------QVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM-VEMPKASMYVWAKIPEPYAAmgSLEFAKK 342
|
330 340 350
....*....|....*....|....*....|....*...
gi 75169651 341 LAHRHGVVVIPGCASGSPGYLRVSFgGLQEVEMRAAAA 378
Cdd:PRK08175 343 LLNEAKVCVSPGIGFGDYGDTHVRF-ALIENRDRIRQA 379
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
62-387 |
5.95e-24 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 102.12 E-value: 5.95e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 62 SSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYyFNSYMAF-QMTGVTN 137
Cdd:PRK07682 51 TSYTANAGLLELRQEIAKYLKKRFAVSydpNDEIIVTVGASQALDVAMRAIINPGDEVLIVEPS-FVSYAPLvTLAGGVP 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 138 IIVGPGQSDTLYPDADWLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGlKH 217
Cdd:PRK07682 130 VPVATTLENEFKVQPAQIEAAIT---AKTKAILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AY 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 218 CC---VEG--DHIVNVFSFSKTYGMMGWRLGYIAYSERLDGFateLVKIQDNIPICAAIISQRLAVYALEEGSGWITERV 292
Cdd:PRK07682 206 TSfasIKGmrERTILISGFSKGFAMTGWRLGFIAAPVYFSEA---MLKIHQYSMMCAPTMAQFAALEALRAGNDDVIRMR 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 293 KSLVKNRDIVKEALEPLGKENVKGGeGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASGSP--GYLRVSFGGLQE 370
Cdd:PRK07682 283 DSYRKRRNFFVTSFNEIGLTCHVPG-GAFYAFPSISSTGLSSEEFAEQLLLEEKVAVVPGSVFGESgeGFIRCSYATSLE 361
|
330
....*....|....*..
gi 75169651 371 vEMRAAAARLRKGIEEL 387
Cdd:PRK07682 362 -QLQEAMKRMKRFVENK 377
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
18-382 |
6.83e-24 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 101.92 E-value: 6.83e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 18 VMAQirslMAELTNPMSLAQGVVHWQPPQKALEKVKELVWDPIiSSYGPDEGLPELRQALLKKLREENKLT---NSQVMV 94
Cdd:PRK09082 22 VMSA----LAAEHGAINLSQGFPDFDGPPYLVEALAYAMAAGH-NQYPPMTGVAALREAIAAKTARLYGRQydaDSEITV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 95 TAGANQAFVNLVITLCDAGDSVVMFEPYYfNSYM-AFQMTGVTNIIVgPGQSDTLYPDADWLERTLSeskPTPKVVTVVN 173
Cdd:PRK09082 97 TAGATEALFAAILALVRPGDEVIVFDPSY-DSYApAIELAGGRAVRV-ALQPPDFRVDWQRFAAAIS---PRTRLIILNT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 174 PGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVEG-----DHIVNVFSFSKTYGMMGWRLGYIAYS 248
Cdd:PRK09082 172 PHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRhpelrERAFVVSSFGKTYHVTGWKVGYCVAP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 249 ERLdgfATELVKIQD------NIPICAAiisqrLAVYALEEgsgwiTERVKSLV----KNRDIVKEALEPlGKENVKGGE 318
Cdd:PRK09082 252 AAL---SAEFRKVHQyntftvNTPAQLA-----LADYLRAE-----PEHYLELPafyqAKRDRFRAALAN-SRFKLLPCE 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75169651 319 GAIYLWAKLPE-GHRDDFKVVRWLAHRHGVVVIP---GCASGSP-GYLRVSFGGlQEVEMRAAAARLRK 382
Cdd:PRK09082 318 GTYFQLVDYSAiSDLDDVEFCQWLTREHGVAAIPlsvFYADPFPhRLVRLCFAK-QEETLDAAAERLCQ 385
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
44-381 |
3.43e-21 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 94.10 E-value: 3.43e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPiiSSYGPD-EGLPELRQALLKKLREENKLT---NSQVMVTAGANQAFVNLVITLCDAGDSVVMF 119
Cdd:PRK07681 46 PADFVREEMVHTANQK--ESYGYTlSGIQEFHEAVTEYYNNTHNVIlnaDKEVLLLMGSQDGLVHLPMVYANPGDIILVP 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 120 EPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDadwLERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGC 199
Cdd:PRK07681 124 DPGYTAYETGIQMAGATSYYMPLKKENDFLPD---LELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNI 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 200 WLIVDNTYEYFMYDG---LKHCCVEGDHIVNV--FSFSKTYGMMGWRLGYIAYSERLDGfatELVKIQDNIPICAAIISQ 274
Cdd:PRK07681 201 IVVHDFAYAEFYFDGnkpISFLSVPGAKEVGVeiNSLSKSYSLAGSRIGYMIGNEEIVR---ALTQFKSNTDYGVFLPIQ 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 275 RLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGkENVKGGEGAIYLWAKLPEGhRDDFKVVRWLAHRHGVVVIPGCA 354
Cdd:PRK07681 278 KAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFG-WNVDKPAGSMFVWAEIPKG-WTSLSFAYALMDRANVVVTPGHA 355
|
330 340 350
....*....|....*....|....*....|
gi 75169651 355 SGS--PGYLRVSFggLQ-EVEMRAAAARLR 381
Cdd:PRK07681 356 FGPhgEGFVRIAL--VQdEEVLQQAVENIR 383
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
45-382 |
8.65e-21 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 93.05 E-value: 8.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 45 PQKALEKVKELVWDPIISSYGPDEGLPELRQALLK--KLREENKLT-NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEP 121
Cdd:PRK09276 46 PDHIIEAMCKAVEDPENHQYPSYEGMLEFRKAVADwyKRRFGVELDpETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDP 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 122 YYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWL-ERTLSESKptpkvVTVVN-PGNPSGTYVPEPLLKRIAQICKDAGC 199
Cdd:PRK09276 126 GYPVYKIGTIFAGGEPYFMPLKEENGFLPDLDAIpEDVAKKAK-----LMFINyPNNPTGAVADLEFFEEVVDFAKKYDI 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 200 WLIVDNTYEYFMYD-----------GLKHCCVEgdhivnVFSFSKTYGMMGWRLGYIAYSERL-DGfateLVKIQDNIP- 266
Cdd:PRK09276 201 IVCHDAAYSEIAYDgykppsflevpGAKDVGIE------FHSLSKTYNMTGWRIGFAVGNADLiAG----LGKVKSNVDs 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 267 -ICAAIisQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEGAIYLWAKLPEGHRD-DFkvVRWLAHR 344
Cdd:PRK09276 271 gVFQAI--QEAGIAALNGPQEVVEELRKIYQERRDILVEGLRKLGLE-VEPPKATFYVWAPVPKGYTSaEF--ATLLLDK 345
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 75169651 345 HGVVVIPGCASGSP--GYLRVSFggLQEVE-MRAAAARLRK 382
Cdd:PRK09276 346 AGVVVTPGNGFGEYgeGYFRIAL--TVPDErIEEAVERIKK 384
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
24-351 |
2.78e-20 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 91.85 E-value: 2.78e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 24 SLMAELTNPMSLAQGVVHWQPPqkalEKVKELVWDPI---ISSYGPDEGLPELRQALLKKLREENKLT---NSQVMVTAG 97
Cdd:PLN00175 48 SSLAIKHGAINLGQGFPNFDGP----DFVKEAAIQAIrdgKNQYARGFGVPELNSAIAERFKKDTGLVvdpEKEVTVTSG 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 98 ANQAFVNLVITLCDAGDSVVMFEPYYfNSYMA-FQMTG--VTNIIVGPgqsdtlyPDADWLERTLSE--SKPTpKVVTVV 172
Cdd:PLN00175 124 CTEAIAATILGLINPGDEVILFAPFY-DSYEAtLSMAGakIKTVTLRP-------PDFAVPEDELKAafTSKT-RAILIN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 173 NPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYdglkhccvEGDHI------------VNVFSFSKTYGMMGW 240
Cdd:PLN00175 195 TPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAF--------EGDHIsmaslpgmyertVTMNSLGKTFSLTGW 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 241 RLGY-IAYSERLDGfateLVKIQDNIPICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEG 319
Cdd:PLN00175 267 KIGWaIAPPHLTWG----VRQAHSFLTFATATPMQWAAVAALRAPESYYEELKRDYSAKKDILVEGLKEVGFK-VYPSSG 341
|
330 340 350
....*....|....*....|....*....|...
gi 75169651 320 AIYLWAK-LPEGHRDDFKVVRWLAHRHGVVVIP 351
Cdd:PLN00175 342 TYFVMVDhTPFGFENDIAFCEYLIEEVGVAAIP 374
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
31-382 |
2.27e-19 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 88.69 E-value: 2.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 31 NPMSLAQGVVHWQPPQKALEKVKELVWDPIiSSYGPDEGLPELRQALLKK---LREENKLTNSQVMVTAGANQAFVNLVI 107
Cdd:PRK12414 30 DALNLSQGAPNFAPDPALVEGVARAMRDGH-NQYAPMAGIAALREALAEKterLYGARYDPASEVTVIASASEGLYAAIS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 108 TLCDAGDSVVMFEPYyFNSYMAF-QMTGVTNIIVgpgqsdTLYPD---ADWLErtlSESKPTPKV-VTVVN-PGNPSGTY 181
Cdd:PRK12414 109 ALVHPGDEVIYFEPS-FDSYAPIvRLQGATPVAI------KLSPEdfrVNWDE---VAAAITPRTrMIIVNtPHNPSATV 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 182 VPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVE-----GDHIVNVFSFSKTYGMMGWRLGY-IAYSERLDgfa 255
Cdd:PRK12414 179 FSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMArhrelAERSVIVSSFGKSYHVTGWRVGYcLAPAELMD--- 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 256 tELVKIQDNIPICAAIISQRLAVYALEEGSGWItERVKSLVKNRDIVKEALEPlGKENVKGGEGAIYLWAKL-PEGHRDD 334
Cdd:PRK12414 256 -EIRKVHQFMVFSADTPMQHAFAEALAEPASYL-GLGAFYQRKRDLLARELAG-SRFELLPSEGSFFMLARFrHFSDESD 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 75169651 335 FKVVRWLAHRHGVVVIPGCA----SGSPGYLRVSFGGlQEVEMRAAAARLRK 382
Cdd:PRK12414 333 SDFVLRLIRDARVATIPLSAfytdGTDTGLIRLSFSK-DDATLVEGARRLCS 383
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
44-381 |
1.80e-18 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 86.38 E-value: 1.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLRE-ENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPY 122
Cdd:TIGR01264 49 TDPEVMQAMKDSLDSGKYNGYAPTVGALSAREAIASYYHNpDGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPG 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 123 YFNSYMAFQMTGVtniivgpgqSDTLY---PDADW------LERTLSESKptpKVVTVVNPGNPSGTYVPEPLLKRIAQI 193
Cdd:TIGR01264 129 FPLYETLAESMGI---------EVKLYnllPDKSWeidlkqLESLIDEKT---AALIVNNPSNPCGSVFSRQHLEEILAV 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 194 CKDAGCWLIVDNTYEYFMYDGLKHCCVEG-DHIVNVFS---FSKTYGMMGWRLGYIAYSERLD---GFATELVKIQDNIP 266
Cdd:TIGR01264 197 AERQCLPIIADEIYGDMVFSGATFEPLASlSSTVPILScggLAKRWLVPGWRLGWIIIHDRRGilrDIRDGLVKLSQRIL 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 267 ICAAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGH----RDDFKVVRWLA 342
Cdd:TIGR01264 277 GPCTIVQGALPSILLRTPQEYFDGTLSVLESNAMLCYGALAAVPGLRPVMPSGAMYMMVGIEMEHfpefKNDVEFTERLV 356
|
330 340 350
....*....|....*....|....*....|....*....
gi 75169651 343 HRHGVVVIPGCASGSPGYLRVSFgGLQEVEMRAAAARLR 381
Cdd:TIGR01264 357 AEQSVFCLPGSCFEYPGFFRVVL-TVPVVMMEEACSRIQ 394
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
48-381 |
2.39e-16 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 80.06 E-value: 2.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 48 ALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREE--NKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY-- 123
Cdd:PLN00143 54 AEDAIVEAVRSAKFNSYAPTGGILPARRAIADYLSNDlpYQLSPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFpd 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 124 FNSYMAFQMTGVTNIivgpgqsdTLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCW 200
Cdd:PLN00143 134 VETYAIFHHLEIRHF--------DLLPEKGWevdLDAVEAIADENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGIL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 201 LIVDNTYEYFMYD-------GLKHCCVEgdhIVNVFSFSKTYGMMGWRLGYIAYSE-----RLDGFATELVKIQDNIPIC 268
Cdd:PLN00143 206 VIADEVYGHIVFGskpfvpmGLFASIVP---VITLGSISKRWMIPGWGLGWLVTCDpsgllQICEIADSIKKALNPAPFP 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 269 AAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKENV-KGGEGAIYLWAKLP----EGHRDDFKVVRWLAH 343
Cdd:PLN00143 283 PTFIQAAIPEILEKTTEDFFSKTINILRAALAFCYDKLKEIPCIMCpQKAEGAFFALVKLNllllEDIEDDMEFCLKLAK 362
|
330 340 350
....*....|....*....|....*....|....*...
gi 75169651 344 RHGVVVIPGCASGSPGYLRVSFgGLQEVEMRAAAARLR 381
Cdd:PLN00143 363 EESLIILPGVTVGLKNWLRITF-AVEQSSLEDGLGRLK 399
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
66-379 |
7.82e-15 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 75.00 E-value: 7.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 66 PDEGLPELRQALLKKLreenKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVmfepYYFNSYMAF----QMTGVTNIIVg 141
Cdd:PRK03321 55 PDMGAVELRAALAEHL----GVPPEHVAVGCGSVALCQQLVQATAGPGDEVI----FAWRSFEAYpilvQVAGATPVQV- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 142 PGQSDTLYpDADWL-----ERTlseskptpKVVTVVNPGNPSGTYVPEPLLKR-IAQICKDagCWLIVDNTYEYFMYDGL 215
Cdd:PRK03321 126 PLTPDHTH-DLDAMaaaitDRT--------RLIFVCNPNNPTGTVVTPAELARfLDAVPAD--VLVVLDEAYVEYVRDDD 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 216 KHCCVE--GDH--IVNVFSFSKTYGMMGWRLGYIAYSERLdgfATELVKIQdnIPICAAIISQRLAVYALeEGSGWITER 291
Cdd:PRK03321 195 VPDGLElvRDHpnVVVLRTFSKAYGLAGLRVGYAVGHPEV---IAALRKVA--VPFSVNSLAQAAAIASL-AAEDELLER 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 292 VKSLVKNRDIVKEALEPLGKEnVKGGEgAIYLWakLPEGHR-DDFKVVrwlAHRHGVVVIPGCASGspgyLRVSFGGLQE 370
Cdd:PRK03321 269 VDAVVAERDRVRAALRAAGWT-VPPSQ-ANFVW--LPLGERtADFAAA---AAEAGVVVRPFAGEG----VRVTIGAPEE 337
|
....*....
gi 75169651 371 VEMRAAAAR 379
Cdd:PRK03321 338 NDAFLRAAR 346
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
43-352 |
1.70e-14 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 74.42 E-value: 1.70e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 43 QPPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKL---TNSQVMVTAGANQAFVNLVITLCDAGDSVVMF 119
Cdd:PRK06207 53 EPTPGAFELFSAGVERGGVQAYTEYRGDADIRELLAARLAAFTGApvdAADELIITPGTQGALFLAVAATVARGDKVAIV 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 120 EPYYF-NSYMAFQMTGVtniIVgPGQSDTLYPDA------DWLERTLsesKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQ 192
Cdd:PRK06207 133 QPDYFaNRKLVEFFEGE---MV-PVQLDYLSADKragldlDQLEEAF---KAGVRVFLFSNPNNPAGVVYSAEEIAQIAA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 193 ICKDAGCWLIVDNTYEYFMYDG-----LKHCCVEGDHIVNVFSFSKTYGMMGWRLGyIAYSERldgfatelvKIQDNIPI 267
Cdd:PRK06207 206 LARRYGATVIVDQLYSRLLYDGtsythLRALPIDPENVITIMGPSKTESLSGYRLG-VAFGSP---------AIIDRMEK 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 268 CAAIISQRLAVYA-------LEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPE---GHRDDFKV 337
Cdd:PRK06207 276 LQAIVSLRAAGYSqavlrtwFSEPDGWMKDRIARHQAIRDDLLRVLRGVEGVFVRAPQAGSYLFPRLPRlavSLHDFVKI 355
|
330
....*....|....*
gi 75169651 338 VRWLAhrhGVVVIPG 352
Cdd:PRK06207 356 LRLQA---GVIVTPG 367
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
149-364 |
1.80e-13 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 71.22 E-value: 1.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 149 YPD-----ADWLERTlseskptpKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDG--LKHCCVE 221
Cdd:PRK06290 166 LPDldsipKDIKEKA--------KLLYLNYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDGkpLSFLSVP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 222 G--DHIVNVFSFSKTYGMMGWRLGYIAYSERL-DGFATelvkIQDN------IPIcaaiisQRLAVYALEEGSgwITERV 292
Cdd:PRK06290 238 GakEVGVEIHSLSKAYNMTGWRLAFVVGNELIvKAFAT----VKDNndsgqfIAI------QKAGIYALDHPE--ITEKI 305
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75169651 293 KSLVKNR-DIVKEALEPLGKENVKGGeGAIYLWAKLPEGHRDDFK------VVRWLAHRHGVVVIPGCASGSpgYLRVS 364
Cdd:PRK06290 306 REKYSRRlDKLVKILNEVGFKAEMPG-GTFYLYVKAPKGTKSGIKfenaeeFSQYLIKEKLISTVPWDDAGH--FLRFS 381
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
44-364 |
7.18e-13 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 69.36 E-value: 7.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPIISSYGPDEGLPELRQALLK--KLREENKLT-NSQVMVTAGANQAFVNLVITLCDAGDSVVMFE 120
Cdd:PRK05942 49 APQPVIEAAIAALADPQNHGYPPFEGTASFRQAITDwyHRRYGVELDpDSEALPLLGSKEGLTHLALAYVNPGDVVLVPS 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 121 PYYFNSYMAFQMTGVT--NIIvgpgqsdtLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICK 195
Cdd:PRK05942 129 PAYPAHFRGPLIAGAQiyPII--------LKPENDWlidLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFAR 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 196 DAGCWLIVDNTYEYFMYDGLKHCCV-----EGDHIVNVFSFSKTYGMMGWRLGY-IAYSERLDGFATelVKIQDNIPICA 269
Cdd:PRK05942 201 KYEIMLVHDLCYAELAFDGYQPTSLleipgAKDIGVEFHTLSKTYNMAGWRVGFvVGNRHIIQGLRT--LKTNLDYGIFS 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 270 AIisQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGkENVKGGEGAIYLWAKLPEG-HRDDFKVVrwLAHRHGVV 348
Cdd:PRK05942 279 AL--QKAAETALQLPDSYLQQVQERYRTRRDFLIQGLGELG-WNIPPTKATMYLWVPCPVGmGSTDFALN--VLQKTGVV 353
|
330
....*....|....*...
gi 75169651 349 VIPGCA--SGSPGYLRVS 364
Cdd:PRK05942 354 VTPGNAfgEGGEGYVRIS 371
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
62-383 |
7.37e-13 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 69.75 E-value: 7.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 62 SSYGPDEGLPELRQALLKKLREE--NKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNSYMAFQMTGVTN 137
Cdd:PLN02187 102 NSYGPGAGILPARRAVADYMNRDlpHKLTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFphYDARAAYSGLEVRK 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 138 IivgpgqsdTLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMY-D 213
Cdd:PLN02187 182 F--------DLLPEKEWeidLEGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFgD 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 214 GLKHCCVEGDHIVNVFSF---SKTYGMMGWRLGYIAYSERLDGFATE--LVKIQDNI---PICAAIISQRLAVYALEEGS 285
Cdd:PLN02187 254 NPFVSMGKFASIVPVLTLagiSKGWVVPGWKIGWIALNDPEGVFETTkvLQSIKQNLdvtPDPATIIQAALPAILEKADK 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 286 GWITERVKSLVKNRDIVKEALEPLGKENV-KGGEGAIYLWAKLP----EGHRDDFKVVRWLAHRHGVVVIPGCASGSPGY 360
Cdd:PLN02187 334 NFFAKKNKILKHNVDLVCDRLKDIPCVVCpKKPESCTYLLTKLElslmDNIKDDIDFCVKLAREENLVFLPGDALGLKNW 413
|
330 340
....*....|....*....|...
gi 75169651 361 LRVSFGglQEVEMRAAAARLRKG 383
Cdd:PLN02187 414 MRITIG--VEAHMLEDALERLKG 434
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
44-380 |
1.35e-12 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 68.66 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 44 PPQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKLTNSQ--------VMVTAGANQAFVNLVITLCDAGDS 115
Cdd:PTZ00433 51 TPAIQTKALVEAVDSQECNGYPPTVGSPEAREAVATYWRNSFVHKESLkstikkdnVVLCSGVSHAILMALTALCDEGDN 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 116 VVMFEPYYFN-----SYMAFQMtgvtniivgpgQSDTLYPDADWlE------RTLSESKptPKVVTVVNPGNPSGTYVPE 184
Cdd:PTZ00433 131 ILVPAPGFPHyetvcKAYGIEM-----------RFYNCRPEKDW-EadldeiRRLVDDR--TKALIMTNPSNPCGSNFSR 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 185 PLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVeGDHIVNVFSF-----SKTYGMMGWRLGYIAYSERlDGFATELV 259
Cdd:PTZ00433 197 KHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSV-ADFDTTVPRVilggtAKNLVVPGWRLGWLLLVDP-HGNGGDFL 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 260 KIQDNIP--ICAA-IISQRLAVYALEEGSGWITER-VKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLP-EGHRD- 333
Cdd:PTZ00433 275 DGMKRLGmlVCGPcSVVQAALGEALLNTPQEHLEQiVAKLEEGAMVLYNHIGECIGLSPTMPRGSMFLMSRLDlEKFRDi 354
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 75169651 334 --DFKVVRWLAHRHGVVVIPGCASGSPGYLRVSFGGLQEVeMRAAAARL 380
Cdd:PTZ00433 355 ksDVEFYEKLLEEENVQVLPGEIFHMPGFTRLTISRPVEV-LREAVERI 402
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
63-365 |
2.71e-12 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 67.87 E-value: 2.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 63 SYGPDEGLPELRQALLKKLREE--NKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNSYMAFQMTGVTNI 138
Cdd:PLN00145 89 SYSTCVGLLPARRAIAEYLSRDlpYELSTDDIYLTAGCAQAIEIIMSVLAQPGANILLPRPGYplYEARAVFSGLEVRHF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 139 ivgpgqsdTLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYdGL 215
Cdd:PLN00145 169 --------DLLPERGWevdLEGVEALADENTVAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTF-GS 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 216 KHCCVEG--DHIVNVF---SFSKTYGMMGWRLGYIAyserldgfATELVKIQDNIPICAAIISQRlavYALEEGSGWITE 290
Cdd:PLN00145 240 KPFVPMGvfGEVAPVLtlgSISKRWVVPGWRLGWIA--------TCDPNGILKETKVVDSIRNYL---NISTDPATFVQG 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 291 RVKSLVKNRD---------IVKEALEpLGKENVKG---------GEGAIYLWAKLP----EGHRDDFKVVRWLAHRHGVV 348
Cdd:PLN00145 309 AIPQIIANTKeefftktlgLLKETAD-ICYEKIKEikcitcphkPEGSMFVMVKLDlsclSGIKDDMDFCCKLAKEESVV 387
|
330
....*....|....*..
gi 75169651 349 VIPGCASGSPGYLRVSF 365
Cdd:PLN00145 388 VLPGSALGMKNWLRITF 404
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
69-385 |
4.29e-12 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 67.47 E-value: 4.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 69 GLPELRQALLKKLRE--ENKLT--NSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNSYMAFQmTGVTNIIVGP 142
Cdd:PLN02450 87 GLPAFKNALAEFMSEirGNKVTfdPNKLVLTAGATSANETLMFCLAEPGDAFLLPTPYYpgFDRDLKWR-TGVEIVPIHC 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 143 GQSDTLYPDADWLERTLSESKP---TPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDG----- 214
Cdd:PLN02450 166 SSSNGFQITESALEEAYQQAQKlnlKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSpgfvs 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 215 ----LKHCCVEGDHIVN----VFSFSKTYGMMGWRLGYIaYS--ERLDGFATE-----LVKIQDNIPICAAIISQRLAVY 279
Cdd:PLN02450 246 vmevLKDRKLENTDVSNrvhiVYSLSKDLGLPGFRVGAI-YSndEMVVSAATKmssfgLVSSQTQYLLSALLSDKKFTKN 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 280 ALEEGSGWITERVKSLVKnrdivkeALEPLGKENVKGGEGaIYLWAKLP--------EGHRDDFKVVrwlAHRHGVVVIP 351
Cdd:PLN02450 325 YLEENQKRLKQRQKKLVS-------GLEAAGIKCLKSNAG-LFCWVDMRhllksntfEAEMELWKKI---VYEVKLNISP 393
|
330 340 350
....*....|....*....|....*....|....*.
gi 75169651 352 G--CASGSPGYLRVSFGGLQEVEMRAAAARLRKGIE 385
Cdd:PLN02450 394 GssCHCTEPGWFRVCFANMSEETLDLAMKRLKSFVE 429
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
46-365 |
5.51e-12 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 66.87 E-value: 5.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 46 QKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREE--NKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY 123
Cdd:PLN02656 51 HVAQEAVVDALQSNKFNGYAPTVGLPQARRAIAEYLSRDlpYKLSLDDVFITSGCTQAIDVALSMLARPGANILLPRPGF 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 124 --FNSYMAFQMTGVTNIivgpgqsdTLYPDADW---LERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAG 198
Cdd:PLN02656 131 piYELCAAFRHLEVRYV--------DLLPEKGWevdLDAVEALADQNTVALVIINPGNPCGNVYSYQHLKKIAETAEKLK 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 199 CWLIVDNTYEYFMYDG--LKHCCVEGDhIVNVF---SFSKTYGMMGWRLGYIAYSERLDGFAT----ELVKIQDNIPICA 269
Cdd:PLN02656 203 ILVIADEVYGHLAFGSnpFVPMGVFGS-IVPVLtlgSLSKRWIVPGWRLGWFVTTDPSGSFRDpkivERIKKYFDILGGP 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 270 AIISQRLAVYALEEGSG-WITERVKSLVKNRDIVKEALEPLGKENVKGG-EGAIYLWAKLP----EGHRDDFKVVRWLAH 343
Cdd:PLN02656 282 ATFIQAAVPTILEQTDEsFFKKTINILKQSSDICCDRIKEIPCITCPHKpEGSMAVMVKLNlsllEDISDDIDFCFKLAR 361
|
330 340
....*....|....*....|..
gi 75169651 344 RHGVVVIPGCASGSPGYLRVSF 365
Cdd:PLN02656 362 EESVIILPGTAVGLKNWLRITF 383
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
149-380 |
6.00e-12 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 66.76 E-value: 6.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 149 YPDADWLErtlseSKPTP--KVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCV---EGD 223
Cdd:PRK09265 155 FPDLDDIR-----SKITPrtKAIVIINPNNPTGAVYSKELLEEIVEIARQHNLIIFADEIYDKILYDGAVHISIaslAPD 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 224 HIVNVFS-FSKTYGMMGWRLGYIAYS---ERLDGFaTELVKIQDNIPICAAIISQrLAVYALEEGSGWITERVKS---LV 296
Cdd:PRK09265 230 LLCVTFNgLSKAYRVAGFRVGWMVLSgpkKHAKGY-IEGLDMLASMRLCANVPAQ-HAIQTALGGYQSINELILPggrLY 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 297 KNRDIVKEALEPL-GKENVKgGEGAIYLWAKL-PEGHR--DDFKVVRWLAHRHGVVVIPGcaSG----SPGYLRVSFggL 368
Cdd:PRK09265 308 EQRDRAWELLNAIpGVSCVK-PKGALYAFPKLdPKVYPihDDEQFVLDLLLQEKVLLVQG--TGfnwpEPDHFRIVT--L 382
|
250
....*....|...
gi 75169651 369 QEVE-MRAAAARL 380
Cdd:PRK09265 383 PRVDdLEEAIGRI 395
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
18-382 |
1.39e-11 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 65.33 E-value: 1.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 18 VMAQIRSLMAELTNPMSLAQGVvHWQP-PQKALEKVKELVWDPIISSYGPDEGLPELRQALLKKLREENKLT---NSQVM 93
Cdd:PRK08068 20 LVAKVNKKVAEGHDVINLGQGN-PDQPtPEHIVEALQEAAENPANHKYSPFRGYPFLKEAAADFYKREYGVTldpETEVA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 94 VTAGANQAFVNLVITLCDAGDSVVMFEPYYfNSYMafqmTGVTniiVGPGQSDT--LYPDADWL---ERTLSESKPTPKV 168
Cdd:PRK08068 99 ILFGGKAGLVELPQCLMNPGDTILVPDPGY-PDYL----SGVA---LARAQFETmpLIAENNFLpdyTKIPEEVAEKAKL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 169 VTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCC---VEG--DHIVNVFSFSKTYGMMGWRLG 243
Cdd:PRK08068 171 MYLNYPNNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSflqTPGakDVGIELYTLSKTFNMAGWRVA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 244 YIAYSERLDGfATELvkIQDNI--PICAAIisQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEPLGKEnVKGGEGAI 321
Cdd:PRK08068 251 FAVGNESVIE-AINL--LQDHLfvSLFGAI--QDAAIEALLSDQSCVAELVARYESRRNAFISACREIGWE-VDAPKGSF 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75169651 322 YLWAKLPEG-HRDDFKVVrwLAHRHGVVVIPGCASGS--PGYLRVsfgGL--QEVEMRAAAARLRK 382
Cdd:PRK08068 325 FAWMPVPKGyTSEQFADL--LLEKAHVAVAPGNGFGEhgEGYVRV---GLltDEERLREAVERIGK 385
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
72-247 |
2.32e-11 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 62.01 E-value: 2.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 72 ELRQALLKKLREENKLTNSQVMVTAGANQAFVNLVITlcdaGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPD 151
Cdd:cd01494 4 ELEEKLARLLQPGNDKAVFVPSGTGANEAALLALLGP----GDEVIVDANGHGSRYWVAAELAGAKPVPVPVDDAGYGGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 152 ADWLERTLsESKPTPKVVTVVNPGNPSGTYVPeplLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVEGDHIVNVFSF 231
Cdd:cd01494 80 DVAILEEL-KAKPNVALIVITPNTTSGGVLVP---LKEIRKIAKEYGILLLVDAASAGGASPAPGVLIPEGGADVVTFSL 155
|
170
....*....|....*.
gi 75169651 232 SKTYGMMGwrLGYIAY 247
Cdd:cd01494 156 HKNLGGEG--GGVVIV 169
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
69-380 |
2.76e-11 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 64.91 E-value: 2.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 69 GLPELRQAL---LKKLRE-ENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNSYMAFQmTGVTNIIVGP 142
Cdd:PLN02607 96 GLKSFRQAMasfMEQIRGgKARFDPDRIVLTAGATAANELLTFILADPGDALLVPTPYYpgFDRDLRWR-TGVKIVPIHC 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 143 GQSDTLYPDADWLERTLSESKPT---PKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTY------------ 207
Cdd:PLN02607 175 DSSNNFQVTPQALEAAYQEAEAAnirVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYsgsvfsasefvs 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 208 -----EYFMYDGLKhccvEGDHIvnVFSFSKTYGMMGWRLGYIaYS---------ERLDGFAteLVKIQDNiPICAAIIS 273
Cdd:PLN02607 255 vaeivEARGYKGVA----ERVHI--VYSLSKDLGLPGFRVGTI-YSyndkvvttaRRMSSFT--LVSSQTQ-HLLASMLS 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 274 QRlavyalEEGSGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGaIYLW---AKLPEGHRDDFKVVRW--LAHRHGVV 348
Cdd:PLN02607 325 DE------EFTENYIRTNRERLRKRYEMIVQGLRRAGIECLKGNAG-LFCWmnlSPLLETPTREGELALWdsILREVKLN 397
|
330 340 350
....*....|....*....|....*....|....
gi 75169651 349 VIPG--CASGSPGYLRVSFGGLQEVEMRAAAARL 380
Cdd:PLN02607 398 ISPGssCHCSEPGWFRVCFANMSEDTLEVALKRI 431
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
155-359 |
1.24e-10 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 63.04 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 155 LERTLSESKP---TPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMY------DGLKHCCVE---G 222
Cdd:PLN02231 258 LKKQLEDARSkgiTVRALVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYvpdkkfHSFKKVARSmgyG 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 223 DHIVNVFSFSKT----YGMMGWRLGYIayseRLDGFATElVKIQ----DNIPICAAIISQRLAVYAL-------EEGSGW 287
Cdd:PLN02231 338 EKDISLVSFQSVskgyYGECGKRGGYM----EVTGFTSD-VREQiykvASVNLCSNISGQILASLVMsppkpgdESYESY 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 288 ITER---VKSLVKNRDIVKEALEPLGKENVKGGEGAIYLWAK--LPE---------GHRDDFKVVRWLAHRHGVVVIPGC 353
Cdd:PLN02231 413 MAEKdgiLSSLARRAKTLEDALNSLEGVTCNKAEGAMYLFPRihLPQkaikaaeaaKTAPDAFYCKRLLNATGIVVVPGS 492
|
....*..
gi 75169651 354 ASGS-PG 359
Cdd:PLN02231 493 GFGQvPG 499
|
|
| PRK09105 |
PRK09105 |
pyridoxal phosphate-dependent aminotransferase; |
70-270 |
1.29e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181651 Cd Length: 370 Bit Score: 62.37 E-value: 1.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 70 LPELRQALLKKLREENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIV---GPGQSD 146
Cdd:PRK09105 76 DLELEDDLRTLFAAQEGLPADHVMAYAGSSEPLNYAVLAFTSPTAGLVTADPTYEAGWRAADAQGAPVAKVplrADGAHD 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 147 tlypdadwLERTLSESkPTPKVVTVVNPGNPSGTYVPeplLKRIAQIC--KDAGCWLIVDNTYEYFmYDG--LKHCCVEG 222
Cdd:PRK09105 156 --------VKAMLAAD-PNAGLIYICNPNNPTGTVTP---RADIEWLLanKPAGSVLLVDEAYIHF-SDApsVVDLVAQR 222
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 75169651 223 DHIVNVFSFSKTYGMMGWRLGY-IAYSERLdgfaTELVKIQDN-IPICAA 270
Cdd:PRK09105 223 KDLIVLRTFSKLYGMAGMRLGLaAARPDLL----AKLARFGHNpLPVPAA 268
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
54-387 |
2.81e-10 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 61.68 E-value: 2.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 54 ELVWD-----PIISSYGPDEGLPELRQALLKKLREENkLTNSQV--MVTAGANQAFVNLVIT-LCDAGDSVVMFEPYYFN 125
Cdd:PRK13355 166 EVVYDmaqqlTDTEGYSDSKGLFSARKAIMQYAQLKG-LPNVDVddIYTGNGVSELINLSMSaLLDDGDEVLIPSPDYPL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 126 SYMAFQMTGVTNIIVGPGQSDTLYPDADWLErtlseSKPTP--KVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIV 203
Cdd:PRK13355 245 WTACVNLAGGTAVHYRCDEQSEWYPDIDDIR-----SKITSrtKAIVIINPNNPTGALYPREVLQQIVDIAREHQLIIFS 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 204 DNTYEYFMYDGLKH---CCVEGDHIVNVFS-FSKTYGMMGWRLGYIAYS--ERLDGFATELVKIQDNIPICAAIISQRLA 277
Cdd:PRK13355 320 DEIYDRLVMDGLEHtsiASLAPDLFCVTFSgLSKSHMIAGYRIGWMILSgnKRIAKDYIEGLNMLANMRLCSNVPAQSIV 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 278 VYALeegsgWITERVKSLV-------KNRDIVKEALEPLGKENVKGGEGAIYLWAKL-PEGH--RDDFKVVRWLAHRHGV 347
Cdd:PRK13355 400 QTAL-----GGHQSVKDYLvpggrvyEQRELVYNALNAIPGISAVKPKAAFYIFPKIdVKKFniHDDEQFALDLLHDKKV 474
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 75169651 348 VVIPGCASG--SPGYLRVSFggLQEVEMraaaarLRKGIEEL 387
Cdd:PRK13355 475 LIVQGTGFNwdKPDHFRVVY--LPRLED------LEDAMDRL 508
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
57-366 |
3.46e-10 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 61.26 E-value: 3.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 57 WDPIISSYGPDEGLP------------ELRQALLKKLREEN------------------------KLTNSQVMVTAGANQ 100
Cdd:COG1168 19 WDGLEDRFGGEDVLPmwvadmdfatppAVIEALKERVEHGVfgytappdeyyeaiidwlkrrhgwEIDPEWIVFTPGVVP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 101 AFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTniIVgpgQSDTLYPDADW------LERTLsesKPTPKVVTVVNP 174
Cdd:COG1168 99 GLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRE--LV---ENPLILEDGRYridfddLEAKL---DPGVKLLLLCNP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 175 GNPSGTyV---PEplLKRIAQICKDAGCWLIVDntyEY---FMYDGLKH------CCVEGDHIVNVFSFSKTYGMMGWRL 242
Cdd:COG1168 171 HNPTGR-VwtrEE--LERLAELCERHDVLVISD---EIhadLVLPGHKHtpfaslSEEAADRTITLTSPSKTFNLAGLKA 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 243 GY-IAYSERL-DGFATELVKIQDNIPicaAIISQRLAVYALEEGSGWITERVKSLVKNRDIVKEALEplgkENVKG---- 316
Cdd:COG1168 245 SYaIIPNPALrARFARALEGLGLPSP---NVLGLVATEAAYREGEEWLDELLAYLRGNRDLLAEFLA----EHLPGvkvt 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 75169651 317 -GEGAiYL-WAKLPEGHRDDFKVVRWLAHRHGVVVIPG--CASGSPGYLRVSFG 366
Cdd:COG1168 318 pPEAT-YLaWLDCRALGLDDEELAEFLLEKAGVALSDGatFGEGGEGFVRLNFA 370
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
61-381 |
7.50e-10 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 60.48 E-value: 7.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 61 ISSYGPDEGLPELRQAL---LKKLREEN-KLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNSYMAFQmTG 134
Cdd:PLN02376 87 IANFQDYHGLKKFRQAIahfMGKARGGKvTFDPERVVMSGGATGANETIMFCLADPGDVFLIPSPYYaaFDRDLRWR-TG 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 135 VTNIIVGPGQSDTL---YPDADWLERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFM 211
Cdd:PLN02376 166 VEIIPVPCSSSDNFkltVDAADWAYKKAQESNKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATV 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 212 YDGLKHCCVEG------------DHIVNVFSFSKTYGMMGWRLGyIAYS---------ERLDGFAteLVKIQDNIPICAA 270
Cdd:PLN02376 246 FAGGDFVSVAEvvndvdisevnvDLIHIVYSLSKDMGLPGFRVG-IVYSfndsvvscaRKMSSFG--LVSSQTQLMLASM 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 271 IISQRLAVYALEEGSGWITERVKSL---VKNRDIVkealeplgkenVKGGEGAIYLWAKLPEGHRD----DFKVVRW--L 341
Cdd:PLN02376 323 LSDDQFVDNFLMESSRRLGIRHKVFttgIKKADIA-----------CLTSNAGLFAWMDLRHLLRDrnsfESEIELWhiI 391
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 75169651 342 AHRHGVVVIPGCA--SGSPGYLRVSFGGLQEVEMRAAAARLR 381
Cdd:PLN02376 392 IDKVKLNVSPGSSfrCTEPGWFRICFANMDDDTLHVALGRIQ 433
|
|
| PRK08637 |
PRK08637 |
hypothetical protein; Provisional |
61-283 |
1.76e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 181512 Cd Length: 388 Bit Score: 58.81 E-value: 1.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 61 ISSYGPDEGLPELRQALLKKLREEN-KLTN---SQVMVTAGANQAfVNLVITL-CDAGDSVVMFEPYYFNSYMAFQMTGV 135
Cdd:PRK08637 37 IFPYAPPQGIPELRDLWQEKMLRENpSLSGkkmSLPIVTNALTHG-LSLVADLfVDQGDTVLLPDHNWGNYKLTFNTRRG 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 136 TNIIVGPGQSDTLYPDADWLERTLSESKPTPKVVTVVN-PGNPSGtYVP-EPLLKRIAQICK---DAGCWL--IVDNTYE 208
Cdd:PRK08637 116 AEIVTYPIFDEDGGFDTDALKEALQAAYNKGKVIVILNfPNNPTG-YTPtEKEATAIVEAIKelaDAGTKVvaVVDDAYF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 209 YFMY-DGLK----------H---CCVEGDhivnvfSFSKTYGMMGWRLGYIAYSERLDGFATEL------VK--IQDNIP 266
Cdd:PRK08637 195 GLFYeDSYKeslfaalanlHsniLAVKLD------GATKEEFVWGFRVGFITFGTKAGSSQTVKealekkVKglIRSNIS 268
|
250
....*....|....*..
gi 75169651 267 iCAAIISQRLAVYALEE 283
Cdd:PRK08637 269 -NGPHPSQSAVLRALNS 284
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
66-366 |
2.40e-09 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 58.61 E-value: 2.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 66 PDEGLPELRQALlkklREENKLTNSQVMVTAGANQafvnLVITLCDA----GDSVVMFEPYYFNSYMAFQMTG--VTNII 139
Cdd:PRK05166 69 PDPQGRALREAI----AARTGVPADRIILGNGSED----LIAVICRAvlrpGDRVVTLYPSFPLHEDYPTMMGarVERVT 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 140 VGPgqsdTLYPDADWLERTLSESkptPKVVTVVNPGNPSGTYVPEPLLKRIAQICkDAGCWLIVDNTY-EYFMYDG---- 214
Cdd:PRK05166 141 VTP----DLGFDLDALCAAVARA---PRMLMFSNPSNPVGSWLTADQLARVLDAT-PPETLIVVDEAYaEYAAGDDypsa 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 215 LKHCCVEGDHIVNVFSFSKTYGMMGWRLGY-IAYSERLDGFateLVKIQDniPICAAIISQRLAVYALEEgSGWITERVK 293
Cdd:PRK05166 213 LTLLKARGLPWIVLRTFSKAYGLAGLRVGYgLVSDPELVGL---LDRVRT--PFNVNGAAQAAALAALDD-EEHLAKGVA 286
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75169651 294 SLVKNRDIVKEALEPLGKENVKGGEGAIYLWAKLPEGhrddfKVVRWLAhRHGVVVIPGCASGSPGYLRVSFG 366
Cdd:PRK05166 287 LALAERERLKKELAEMGYRIAPSRANFLFFDARRPAS-----AVAEALL-RQGVIVKPWKQPGFETFIRVSIG 353
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
79-246 |
2.03e-08 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 55.12 E-value: 2.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 79 KKLREE-NKLTNSQVMVTAGANQAFVNLVITLCDaGDSVVMFEPYYFNSYMAFQMTGvTNIIVGPgqsdtLYPDadwler 157
Cdd:PRK08354 43 EWLEEEfSKLFGEPIVITAGITEALYLIGILALR-DRKVIIPRHTYGEYERVARFFA-ARIIKGP-----NDPE------ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 158 TLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKhccVEGDHIVNVFSFSKTYGM 237
Cdd:PRK08354 110 KLEELVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAFIDFVKKPES---PEGENIIKLRTFTKSYGL 186
|
....*....
gi 75169651 238 MGWRLGYIA 246
Cdd:PRK08354 187 PGIRVGYVK 195
|
|
| PRK03317 |
PRK03317 |
histidinol-phosphate aminotransferase; Provisional |
66-387 |
3.02e-08 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 235115 Cd Length: 368 Bit Score: 54.87 E-value: 3.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 66 PDEGLPELRQALLKKLREEN--KLTNSQVMVTAGAN-------QAFVNlvitlcdAGDSVVMFEPYYfnsymafQM---- 132
Cdd:PRK03317 63 PDRDAVALRADLAAYLTAQTgvGLTVENVWAANGSNeilqqllQAFGG-------PGRTALGFVPSY-------SMhpii 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 133 ---TGvTNIIVGPGQSD-TLypDADWLERTLSESKPTpkVVTVVNPGNPSGTYVPeplLKRIAQICKDAGCWLIVDNTYE 208
Cdd:PRK03317 129 argTH-TEWVEGPRAADfTL--DVDAAVAAIAEHRPD--VVFLTSPNNPTGTALP---LDDVEAILDAAPGIVVVDEAYA 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 209 YFMYDGLKHCC--VEG-DHIVNVFSFSKTYGMMGWRLGYIAYSERL-DgfATELVKiqdnIPICAAIISQRLAVYALEEg 284
Cdd:PRK03317 201 EFRRSGTPSALtlLPEyPRLVVSRTMSKAFAFAGGRLGYLAAAPAVvD--ALRLVR----LPYHLSAVTQAAARAALRH- 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 285 SGWITERVKSLVKNRDIVKEALEPLGKENVKGGEGAIYLwaklpeGHRDDFKVVrWLAH-RHGVVVIpgcASGSPGYLRV 363
Cdd:PRK03317 274 ADELLASVAALRAERDRVVAWLRELGLRVAPSDANFVLF------GRFADRHAV-WQGLlDRGVLIR---DVGIPGWLRV 343
|
330 340
....*....|....*....|....*
gi 75169651 364 SFGGLQEVE-MRAAAARLRKGIEEL 387
Cdd:PRK03317 344 TIGTPEENDaFLAALAEVLATELAA 368
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
149-387 |
7.84e-08 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 54.10 E-value: 7.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 149 YPDADwLERTLSeskPTPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIV--DNTYEYF------MYDGLKHccv 220
Cdd:PRK09275 229 YPDSE-LEKLRD---PSIKALFLVNPSNPPSVAMSDESLEKIADIVNEKRPDLMIitDDVYGTFvddfrsLFAVLPY--- 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 221 egdHIVNVFSFSKTYGMMGWRLGYIAYSER--LDGFATELVKIQ---------------DNIP----ICA---------- 269
Cdd:PRK09275 302 ---NTILVYSFSKYFGATGWRLGVIALHEDnvFDKLIAKLPEEKkkeldkrysslttdpEKLKfidrLVAdsrqvalnht 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 270 AIIS--QRL-----AVYAL-EEGSGWItERVKSLVKNRdivKEAL-------EPLGKENVK-GGEGAIYLWAKLPEGhrD 333
Cdd:PRK09275 379 AGLStpQQVqmalfSLFALlDEEDAYK-KAMKDIIRRR---YKALyeglglpEPEDPNNAAyYTLIDLEEWAEKNYG--K 452
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 75169651 334 DFkvVRW-------------LAHRHGVVVIPGCASGSP-GYLRVSFGGLQEVEMRAAAARLRKGIEEL 387
Cdd:PRK09275 453 EF--ADYlkknyspvdllfrLAEETGVVLLPGGGFGGPeWSVRVSLANLNEEDYAKIGKAIRKLLDEY 518
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
23-352 |
2.53e-07 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 52.27 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 23 RSLMAELTNPMSLAQGVVHWQPPQKALEKVKElvwdpIISS-------YGPDEGLPELRQALLKKL--REENKLTNSQVM 93
Cdd:PTZ00377 68 RQVLSLVEYPFLLEDPSVSSLFPADVVARAKE-----YLNAigggtgaYTDSAGYPFVRKAVAAFIerRDGVPKDPSDIF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 94 VTAGANQA---FVNLVITlcDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPGQSDTLYPDADWLERTLSESKP---TPK 167
Cdd:PTZ00377 143 LTDGASSGiklLLQLLIG--DPSDGVMIPIPQYPLYSAAITLLGGKQVPYYLDEEKGWSLDQEELEEAYEQAVRngiTPR 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 168 VVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDG----------LKHCCVEGDHIVNVFSF---SK- 233
Cdd:PTZ00377 221 ALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGekpfisfrkvLLELPAEYNTDVELVSFhstSKg 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 234 TYGMMGWRLGYIAYsERLDGFATE-LVKIQdNIPICAAIISQRLAVY-----ALEEGSGWI--TER---VKSLVKNRDIV 302
Cdd:PTZ00377 301 IIGECGRRGGYFEL-TNIPPEVREqIYKLA-SINLCSNVVGQLMTGLmcnppREGDASYPLykRERdaiFTSLKRRAELL 378
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75169651 303 KEALeplgkENVKG-----GEGAIYLWAK--LPEG---HRDDFKV---VRW---LAHRHGVVVIPG 352
Cdd:PTZ00377 379 TDEL-----NKIEGvscqpVEGAMYAFPRieLPEKaiqEAKERGLapdVLYcleLLESTGIVVVPG 439
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
149-218 |
8.19e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 50.72 E-value: 8.19e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75169651 149 YPDADWLERTLsesKPTPKVV--TVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHC 218
Cdd:PRK06855 156 YPDLDDLENKV---KYNPSIAgiLLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTV 224
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
101-207 |
1.91e-06 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 49.51 E-value: 1.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 101 AFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMT----GVTniivgpgqsdTLYPDADWLERTLSESKPTPKVVTVVNPGN 176
Cdd:cd00614 67 AISTVLLALLKAGDHVVASDDLYGGTYRLFERLlpklGIE----------VTFVDPDDPEALEAAIKPETKLVYVESPTN 136
|
90 100 110
....*....|....*....|....*....|.
gi 75169651 177 PSGTYVPeplLKRIAQICKDAGCWLIVDNTY 207
Cdd:cd00614 137 PTLKVVD---IEAIAELAHEHGALLVVDNTF 164
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
12-352 |
2.95e-06 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 49.08 E-value: 2.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 12 LGTDMPvmAQI-------RSLMAELTNPMSLAQGVVHWQPPQkalekvkelvwdpiissygpdeGLPELRQALLKKLREE 84
Cdd:PRK09440 35 LGGGNP--AHIpemedyfRDLLADLLASGKLTEALGNYDGPQ----------------------GKDELIEALAALLNER 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 85 N--KLTNSQVMVTAGANQAFVNLvitlcdagdsvvmfepyyFNSYMAFQMTGVTNIIVGP------GQSD-TLYPDA--- 152
Cdd:PRK09440 91 YgwNISPQNIALTNGSQSAFFYL------------------FNLFAGRRADGSLKKILFPlapeyiGYADaGLEEDLfvs 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 153 -----DWL-ERT------LSESKPTPKV--VTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEyFMYDGLkhC 218
Cdd:PRK09440 153 yrpniELLpEGQfkyhvdFEHLHIDEDTgaICVSRPTNPTGNVLTDEELEKLDALARQHNIPLLIDNAYG-PPFPGI--I 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 219 CVE-----GDHIVNVFSFSKTyGMMGWRLGYIAYSERldgFATELVKIQDNIPICAAIISQRLAVYALEEGS--GWITER 291
Cdd:PRK09440 230 FSEatplwNPNIILCMSLSKL-GLPGVRCGIVIADEE---IIEALSNMNGIISLAPGRLGPAIAAEMIESGDllRLSETV 305
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75169651 292 VKSLVKNR-DIVKEAL-EPLGKENVK--GGEGAIYLWAKLPeghrdDFKVVRW-LAHR---HGVVVIPG 352
Cdd:PRK09440 306 IRPFYRQKvQLAIALLrRYLPDEPCLihKPEGAIFLWLWFK-----DLPITTEeLYQRlkaRGVLVVPG 369
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
66-247 |
3.41e-06 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 48.54 E-value: 3.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 66 PDeglPELRQaLLKKLREENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEP----YYFNSymAFQMTGVTNIIVG 141
Cdd:PLN03026 84 PD---PESRR-LRAALAEDSGLESENILVGCGADELIDLLMRCVLDPGDKIIDCPPtfgmYVFDA--AVNGAEVIKVPRT 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 142 PGQSdtlyPDADWLERTLSESKPtpKVVTVVNPGNPSGTYVPEPLLKRIAQIckdaGCWLIVDNTYEYF------MYDGL 215
Cdd:PLN03026 158 PDFS----LDVPRIVEAVETHKP--KLLFLTSPNNPDGSIISDDDLLKILEL----PILVVLDEAYIEFstqesrMKWVK 227
|
170 180 190
....*....|....*....|....*....|..
gi 75169651 216 KHccvegDHIVNVFSFSKTYGMMGWRLGYIAY 247
Cdd:PLN03026 228 KY-----DNLIVLRTFSKRAGLAGLRVGYGAF 254
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
101-207 |
2.76e-05 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 45.69 E-value: 2.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 101 AFVNLVITLCDAGDSVVMFEPYYFNSYMAFqmtgvtNIIVGPGQSDTLYPDADWLERTLSESKPTPKVVTVVNPGNPsgT 180
Cdd:pfam01053 74 AITAAILALLKAGDHIVATDDLYGGTYRLF------NKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNP--L 145
|
90 100
....*....|....*....|....*...
gi 75169651 181 Y-VPEplLKRIAQICKDAGCWLIVDNTY 207
Cdd:pfam01053 146 LkVVD--IEAIAKLAKKHGILVVVDNTF 171
|
|
| SepCysS |
cd06452 |
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent ... |
91-207 |
8.14e-05 |
|
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Cys-tRNA(Cys) is produced by O-phosphoseryl-tRNA synthetase which ligates O-phosphoserine (Sep) to tRNA(Cys), and Sep-tRNA:Cys-tRNA synthase (SepCysS) converts Sep-tRNA(Cys) to Cys-tRNA(Cys), in methanogenic archaea. SepCysS forms a dimer, each monomer is composed of a large and small domain; the larger, a typical pyridoxal 5'-phosphate (PLP)-dependent-like enzyme fold. In the active site of each monomer, PLP is covalently bound to a conserved Lys residue near the dimer interface.
Pssm-ID: 99745 Cd Length: 361 Bit Score: 44.30 E-value: 8.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 91 QVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVtNIIVGPGQSDTLY---PD--ADWLERTLSESKPT 165
Cdd:cd06452 61 EARVTPGAREGKFAVMHSLCEKGDWVVVDGLAHYTSYVAAERAGL-NVREVPNTGHPEYhitPEgyAEVIEEVKDEFGKP 139
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 75169651 166 PKVVTVVnpgNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTY 207
Cdd:cd06452 140 PALALLT---HVDGNYGNLHDAKKIAKVCHEYGVPLLLNGAY 178
|
|
| PRK08153 |
PRK08153 |
pyridoxal phosphate-dependent aminotransferase; |
72-300 |
1.04e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181255 Cd Length: 369 Bit Score: 43.83 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 72 ELRQALLKKLReenkLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY--FNsymaFQMTGVTNIIVG-PGQSDTL 148
Cdd:PRK08153 71 DLRHALAAHHG----VAPENIMVGEGIDGLLGLIVRLYVEPGDPVVTSLGAYptFN----YHVAGFGGRLVTvPYRDDRE 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 149 YPDAdWLERTLSESkptPKVVTVVNPGNPSGTYVPEPLLKRIAqickDA---GCWLIVDNTY-EYFMYDGLKHCCVEGDH 224
Cdd:PRK08153 143 DLDA-LLDAARREN---APLVYLANPDNPMGSWHPAADIVAFI----EAlpeTTLLVLDEAYcETAPAGAAPPIDTDDPN 214
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 75169651 225 IVNVFSFSKTYGMMGWRLGY-IAYSERLDGFAtelvKIQDNIPIcaAIISQRLAVYALEEgSGWITERVKSLVKNRD 300
Cdd:PRK08153 215 VIRMRTFSKAYGLAGARVGYaIGAPGTIKAFD----KVRNHFGM--NRIAQAAALAALKD-QAYLAEVVGKIAAARD 284
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
97-207 |
1.19e-04 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 43.94 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 97 GANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAfqMTGVTNIIvgpGQSDTlYPDADWLERTLSESKPTPKVVTVVNPGN 176
Cdd:PRK07671 72 GSGMAAITAVMMLFSSGDHVILTDDVYGGTYRV--MTKVLNRF---GIEHT-FVDTSNLEEVEEAIRPNTKAIYVETPTN 145
|
90 100 110
....*....|....*....|....*....|....*.
gi 75169651 177 PsgtyvpepLLK-----RIAQICKDAGCWLIVDNTY 207
Cdd:PRK07671 146 P--------LLKitdikKISTIAKEKGLLTIVDNTF 173
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
151-321 |
1.52e-04 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 43.32 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 151 DADWLERTLSESKPTPKVVTVVNPGNPS--GTYVPeplLKRIAQICKDAGCWLIVDNTYEYFMYD----GLKHCCVEGDH 224
Cdd:cd06454 116 DMEDLEKLLREARRPYGKKLIVTEGVYSmdGDIAP---LPELVDLAKKYGAILFVDEAHSVGVYGphgrGVEEFGGLTDD 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 225 I-VNVFSFSKTYGMMGwrlGYIAYSERL-D---------GFATELvkiqdNIPICAAIISqrlAVYALEEGsgwiTERVK 293
Cdd:cd06454 193 VdIIMGTLGKAFGAVG---GYIAGSKELiDylrsyargfIFSTSL-----PPAVAAAALA---ALEVLQGG----PERRE 257
|
170 180
....*....|....*....|....*...
gi 75169651 294 SLVKNRDIVKEALEPLGkENVKGGEGAI 321
Cdd:cd06454 258 RLQENVRYLRRGLKELG-FPVGGSPSHI 284
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
59-388 |
3.75e-04 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 42.28 E-value: 3.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 59 PIISSYGPDegLPELRQALLKKLREENKLTNSQVMVTAGANQ-----AFVNLVitlcDAGDSVVMFEPYYFNSYMAfQMT 133
Cdd:cd06451 21 PMLGHRSPE--FLALMDEILEGLRYVFQTENGLTFLLSGSGTgameaALSNLL----EPGDKVLVGVNGVFGDRWA-DMA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 134 G-----VTNIIVGPGQSDTLYPDADWLErtlsesKPTPKVVTVVNpgNPSGTYVPEPLlKRIAQICKDAGCWLIVDNT-- 206
Cdd:cd06451 94 ErygadVDVVEKPWGEAVSPEEIAEALE------QHDIKAVTLTH--NETSTGVLNPL-EGIGALAKKHDALLIVDAVss 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 207 ---YEYFMyDGLK-HCCVEGDHIVnvfsFSKTYGmmgwrLGYIAYSER-LDGFAT------------ELVKIQDN----- 264
Cdd:cd06451 165 lggEPFRM-DEWGvDVAYTGSQKA----LGAPPG-----LGPIAFSERaLERIKKktkpkgfyfdllLLLKYWGEgysyp 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 265 --IPIcAAIISQRLAV-YALEEGsgwITERVKSLVKNRDIVKEALEPLGKEN--VKGGEGAIYLWAKLPEGHRDDfKVVR 339
Cdd:cd06451 235 htPPV-NLLYALREALdLILEEG---LENRWARHRRLAKALREGLEALGLKLlaKPELRSPTVTAVLVPEGVDGD-EVVR 309
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 75169651 340 WLAHRHGVVVIPGCASGSPGYLRVSFGGLQEVEMRAAAArlrKGIEELL 388
Cdd:cd06451 310 RLMKRYNIEIAGGLGPTAGKVFRIGHMGEATREDVLGVL---SALEEAL 355
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
91-207 |
4.04e-04 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 42.30 E-value: 4.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 91 QVMVTAGANQAFVNLVITLCDAGDSVVMFEPYY------FNSYMAfqMTGVtniivgpgqsDTLYPDADWLERTLSESKP 164
Cdd:PRK08133 78 ACVATASGMAAILAVVMALLQAGDHVVSSRSLFgstvslFEKIFA--RFGI----------ETTFVDLTDLDAWRAAVRP 145
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 75169651 165 TPKVVTVVNPGNPSGTYVPeplLKRIAQICKDAGCWLIVDNTY 207
Cdd:PRK08133 146 NTKLFFLETPSNPLTELAD---IAALAEIAHAAGALLVVDNCF 185
|
|
| PRK09331 |
PRK09331 |
Sep-tRNA:Cys-tRNA synthetase; Provisional |
91-207 |
1.16e-03 |
|
Sep-tRNA:Cys-tRNA synthetase; Provisional
Pssm-ID: 236469 Cd Length: 387 Bit Score: 40.68 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 91 QVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTGVTNIIVGPgqsdTLYPD--------ADWLERTLSES 162
Cdd:PRK09331 80 EARVTHGAREGKFAVMHSLCKKGDYVVLDGLAHYTSYVAAERAGLNVREVPK----TGYPEykitpeayAEKIEEVKEET 155
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 75169651 163 KPTPKVVTVVnpgNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTY 207
Cdd:PRK09331 156 GKPPALALLT---HVDGNYGNLADAKKVAKVAHEYGIPFLLNGAY 197
|
|
| PRK06425 |
PRK06425 |
histidinol-phosphate aminotransferase; Validated |
166-249 |
1.22e-03 |
|
histidinol-phosphate aminotransferase; Validated
Pssm-ID: 102370 Cd Length: 332 Bit Score: 40.61 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 166 PKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMYDGLKHCCVEGDHIVNVF---SFSKTYGMMGWRL 242
Cdd:PRK06425 123 FDLIFIVSPDNPLGNLISRDSLLTISEICRKKGALLFIDEAFIDFVPNRAEEDVLLNRSYGNVIigrSLTKILGIPSLRI 202
|
....*..
gi 75169651 243 GYIAYSE 249
Cdd:PRK06425 203 GYIATDD 209
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
105-207 |
1.96e-03 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 40.03 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 105 LVITLCDAGDSVVMFEPYYFNSYMAFQMT----GVTNIIVGPGqsdtlypDADWLERTLsesKPTPKVVTVVNPGNPsgt 180
Cdd:COG0626 89 VLLALLKAGDHVVASDDLYGGTRRLLDKVlarfGIEVTFVDPT-------DLAAVEAAI---RPNTKLVFLETPSNP--- 155
|
90 100 110
....*....|....*....|....*....|..
gi 75169651 181 yvpepLLK-----RIAQICKDAGCWLIVDNTY 207
Cdd:COG0626 156 -----TLEvvdiaAIAAIAHAAGALLVVDNTF 182
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
101-207 |
6.46e-03 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 38.53 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 101 AFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMtGVTNIIVGPGQSDTlyPDADWLERTLSeskPTPKVVTVVNPGNPsgt 180
Cdd:PRK08247 78 AAIQLVMSLFRSGDELIVSSDLYGGTYRLFEE-HWKKWNVRFVYVNT--ASLKAIEQAIT---PNTKAIFIETPTNP--- 148
|
90 100
....*....|....*....|....*..
gi 75169651 181 YVPEPLLKRIAQICKDAGCWLIVDNTY 207
Cdd:PRK08247 149 LMQETDIAAIAKIAKKHGLLLIVDNTF 175
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
61-212 |
7.14e-03 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 38.24 E-value: 7.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75169651 61 ISSYGPDEGLPELRQALLKKLREENKLTNS--QVMVTAGANQAFVNLVITLC-DAGDSVVMFEPYYFNSYMAFQMTGVTN 137
Cdd:PLN02368 100 LGAYSDSRGLPGVRKEVAEFIERRDGYPSDpeLIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQYPLYSATISLLGGTL 179
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 75169651 138 IIVGPGQSDTLYPDADWLERTLSESKP---TPKVVTVVNPGNPSGTYVPEPLLKRIAQICKDAGCWLIVDNTYEYFMY 212
Cdd:PLN02368 180 VPYYLEESENWGLDVNNLRQSVAQARSkgiTVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVLLGDEVYQQNIY 257
|
|
| |
