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Conserved domains on  [gi|75161591|sp|Q8VZ59|]
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RecName: Full=Indole-3-pyruvate monooxygenase YUCCA6; AltName: Full=Flavin-containing monooxygenase YUCCA6; AltName: Full=Protein HYPERTALL1

Protein Classification

flavin-containing monooxygenase( domain architecture ID 11449697)

flavin-containing monooxygenase (FMO) catalyses the flavin-dependent oxidation of ketones and cyclic ketones to esters and lactones, by using molecular oxygen and NAD(P)H.

CATH:  3.50.50.60
Gene Ontology:  GO:0016709|GO:0004497|GO:0050660
PubMed:  20015679|33588053

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-411 1.26e-83

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


:

Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 261.72  E-value: 1.26e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLKTYDRLHLHLPKQFCELPIIPFPGDFPTYPTKQQFIEYLEDY 112
Cdd:COG2072  10 VVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTGDEILAYLEAY 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 113 ARRFDIKP--EFNQTVESAAFDENLGMWRVTSVGEEgttEYVCRWLVAATGENAEPVVPRFEGMDKFaaAGVVKHTCHYK 190
Cdd:COG2072  90 ADKFGLRRpiRFGTEVTSARWDEADGRWTVTTDDGE---TLTARFVVVATGPLSRPKIPDIPGLEDF--AGEQLHSADWR 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 191 TGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAVHVLPR----EMLGTSTFGLSMFLLKWLPIRLVDRFLLVV 266
Cdd:COG2072 165 NPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnydPERGRPANYLGLEAPPALNRRDARAWLRRL 244

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 267 SRFILGDTTlLGLNRPRLGPLelknisGKTPVLDVGTLAKIKTGDIK-VCSGIRRLKRHEVEFDNGKTERFDAIILATGY 345
Cdd:COG2072 245 LRAQVKDPE-LGLLTPDYPPG------CKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEHEVDVIVWATGF 317

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75161591 346 KSNVPsWLKENKMFSkKDGfpiQEFPEGWRGEC-----GLYAVGF-TKRGIS----GASMDAKRIAEDIHKCWKQD 411
Cdd:COG2072 318 RADLP-WLAPLDVRG-RDG---RSGPRAYLGVVvpgfpNLFFLGPnSPSGHSsltlGAERQARYIARLIAHMRRRG 388
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-411 1.26e-83

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 261.72  E-value: 1.26e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLKTYDRLHLHLPKQFCELPIIPFPGDFPTYPTKQQFIEYLEDY 112
Cdd:COG2072  10 VVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTGDEILAYLEAY 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 113 ARRFDIKP--EFNQTVESAAFDENLGMWRVTSVGEEgttEYVCRWLVAATGENAEPVVPRFEGMDKFaaAGVVKHTCHYK 190
Cdd:COG2072  90 ADKFGLRRpiRFGTEVTSARWDEADGRWTVTTDDGE---TLTARFVVVATGPLSRPKIPDIPGLEDF--AGEQLHSADWR 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 191 TGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAVHVLPR----EMLGTSTFGLSMFLLKWLPIRLVDRFLLVV 266
Cdd:COG2072 165 NPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnydPERGRPANYLGLEAPPALNRRDARAWLRRL 244

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 267 SRFILGDTTlLGLNRPRLGPLelknisGKTPVLDVGTLAKIKTGDIK-VCSGIRRLKRHEVEFDNGKTERFDAIILATGY 345
Cdd:COG2072 245 LRAQVKDPE-LGLLTPDYPPG------CKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEHEVDVIVWATGF 317

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75161591 346 KSNVPsWLKENKMFSkKDGfpiQEFPEGWRGEC-----GLYAVGF-TKRGIS----GASMDAKRIAEDIHKCWKQD 411
Cdd:COG2072 318 RADLP-WLAPLDVRG-RDG---RSGPRAYLGVVvpgfpNLFFLGPnSPSGHSsltlGAERQARYIARLIAHMRRRG 388
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 34-366 1.34e-32

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 128.74  E-value: 1.34e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    34 IVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLK---------TYDRLHLHLPKQFCELPIIPFPGDFPTYPTKQQ 104
Cdd:pfam00743   6 VIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTenveegrasIYKSVITNTSKEMSCFSDFPFPEDYPNFMHNSK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   105 FIEYLEDYARRFDIKP--EFNQTVESAA----FDENlGMWRVTSVGEEGTTEYVCRWLVAATGENAEPVVP--RFEGMDK 176
Cdd:pfam00743  86 FLEYFRMFAKEFDLLKyiQFKTTVCSVKkrpdFSTS-GQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPleSFPGIEK 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   177 FAaaGVVKHTCHYKTGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAVHVL--------PREMLGTSTFGlsM 248
Cdd:pfam00743 165 FK--GQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLsrvsdhgyPWDMLFSTRFT--S 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   249 FLLKWLPIRLVDRFLL--VVSRFILGDTTLLGLNRPRLgplelknisgKTPVLDVGTLAKIKTGDIKVCSGIRRLKRHEV 326
Cdd:pfam00743 241 FLRNILPTSISNWLMEkqMNRRFNHENYGLKPKNRALS----------KEPVVNDDLPNRILCGAVKVKPNVKEFTETSA 310

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 75161591   327 EFDNG-KTERFDAIILATGYKSNVP----SWLK--ENKMFSKKDGFP 366
Cdd:pfam00743 311 IFEDGtVEEDIDVVIFATGYTFAFPfleeSLVKveNNKVSLYKYVFP 357
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 33-216 3.05e-13

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 71.05  E-value: 3.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLW--------------------QLKTYDRLHLHLPKQ---FCELPI 89
Cdd:PLN02172  14 AVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWvytpksesdplsldptrsivHSSVYESLRTNLPREcmgYRDFPF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   90 IPFPGDFP----TYPTKQQFIEYLEDYARRFDIKPEFNQTVESAAFDENLGMWRVTSVGEEGTTEY-VCRWLVAATGENA 164
Cdd:PLN02172  94 VPRFDDESrdsrRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVEPVDGKWRVQSKNSGGFSKDeIFDAVVVCNGHYT 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 75161591  165 EPVVPRFEGMDKFAAAGVvkHTCHYKTGGDFAGKRVLVVGCGNSGMEVCLDL 216
Cdd:PLN02172 174 EPNVAHIPGIKSWPGKQI--HSHNYRVPDPFKNEVVVVIGNFASGADISRDI 223
NAD_bind_Leu_Phe_Val_DH cd01075
NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine ...
 175-229 4.59e-03

NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Amino acid dehydrogenase (DH) is a widely distributed family of enzymes that catalyzes the oxidative deamination of an amino acid to its keto acid and ammonia with concomitant reduction of NADP+. For example, leucine DH catalyzes the reversible oxidative deamination of L-leucine and several other straight or branched chain amino acids to the corresponding 2-oxoacid derivative. Amino acid DH -like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.


Pssm-ID: 133444  Cd Length: 200  Bit Score: 37.96  E-value: 4.59e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 75161591 175 DKFAAAGV---VKHTCHYKTGGD-FAGKRVLVVGCGNSGMEVCLDLCNFGAQpsLVVRD 229
Cdd:cd01075   2 SPPTAYGVflgMKAAAEHLLGTDsLEGKTVAVQGLGKVGYKLAEHLLEEGAK--LIVAD 58
 
Name Accession Description Interval E-value
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 33-411 1.26e-83

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 261.72  E-value: 1.26e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLKTYDRLHLHLPKQFCELPIIPFPGDFPTYPTKQQFIEYLEDY 112
Cdd:COG2072  10 VVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTGDEILAYLEAY 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 113 ARRFDIKP--EFNQTVESAAFDENLGMWRVTSVGEEgttEYVCRWLVAATGENAEPVVPRFEGMDKFaaAGVVKHTCHYK 190
Cdd:COG2072  90 ADKFGLRRpiRFGTEVTSARWDEADGRWTVTTDDGE---TLTARFVVVATGPLSRPKIPDIPGLEDF--AGEQLHSADWR 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 191 TGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAVHVLPR----EMLGTSTFGLSMFLLKWLPIRLVDRFLLVV 266
Cdd:COG2072 165 NPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnydPERGRPANYLGLEAPPALNRRDARAWLRRL 244

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 267 SRFILGDTTlLGLNRPRLGPLelknisGKTPVLDVGTLAKIKTGDIK-VCSGIRRLKRHEVEFDNGKTERFDAIILATGY 345
Cdd:COG2072 245 LRAQVKDPE-LGLLTPDYPPG------CKRPLLSTDYYEALRRGNVElVTGGIERITEDGVVFADGTEHEVDVIVWATGF 317

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75161591 346 KSNVPsWLKENKMFSkKDGfpiQEFPEGWRGEC-----GLYAVGF-TKRGIS----GASMDAKRIAEDIHKCWKQD 411
Cdd:COG2072 318 RADLP-WLAPLDVRG-RDG---RSGPRAYLGVVvpgfpNLFFLGPnSPSGHSsltlGAERQARYIARLIAHMRRRG 388
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 34-366 1.34e-32

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 128.74  E-value: 1.34e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    34 IVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLK---------TYDRLHLHLPKQFCELPIIPFPGDFPTYPTKQQ 104
Cdd:pfam00743   6 VIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTenveegrasIYKSVITNTSKEMSCFSDFPFPEDYPNFMHNSK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   105 FIEYLEDYARRFDIKP--EFNQTVESAA----FDENlGMWRVTSVGEEGTTEYVCRWLVAATGENAEPVVP--RFEGMDK 176
Cdd:pfam00743  86 FLEYFRMFAKEFDLLKyiQFKTTVCSVKkrpdFSTS-GQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPleSFPGIEK 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   177 FAaaGVVKHTCHYKTGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAVHVL--------PREMLGTSTFGlsM 248
Cdd:pfam00743 165 FK--GQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLsrvsdhgyPWDMLFSTRFT--S 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   249 FLLKWLPIRLVDRFLL--VVSRFILGDTTLLGLNRPRLgplelknisgKTPVLDVGTLAKIKTGDIKVCSGIRRLKRHEV 326
Cdd:pfam00743 241 FLRNILPTSISNWLMEkqMNRRFNHENYGLKPKNRALS----------KEPVVNDDLPNRILCGAVKVKPNVKEFTETSA 310

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 75161591   327 EFDNG-KTERFDAIILATGYKSNVP----SWLK--ENKMFSKKDGFP 366
Cdd:pfam00743 311 IFEDGtVEEDIDVVIFATGYTFAFPfleeSLVKveNNKVSLYKYVFP 357
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
39-367 9.56e-21

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 91.52  E-value: 9.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    39 PSGLATAACLKERGITSVL-LERSNCIASLwqlktydrlhLHLPK--QF---------CELPIIPF--PGDFPT------ 98
Cdd:pfam13738   1 PAGIGCAIALKKAGLEDYLiLEKGNIGNSF----------YRYPThmTFfspsftsngFGIPDLNAisPGTSPAftfnre 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    99 YPTKQQFIEYLEDYARRFDIKPEFNQTVESAAFDENLgmWRVTSVGEEgtteYVCRWLVAATGENAEPVVPRFEGMdkfa 178
Cdd:pfam13738  71 HPSGNEYAEYLRRVADHFELPINLFEEVTSVKKEDDG--FVVTTSKGT----YQARYVIIATGEFDFPNKLGVPEL---- 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   179 aagvVKHTCHYKTGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAvhvlPREMLGTStfglsmfllkwlpirl 258
Cdd:pfam13738 141 ----PKHYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGS----EWEDRDSD---------------- 196

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   259 vdrfllvVSRFILGDTtllglnRPRLGPLElknISGKTPVLDVGTLAKIKTGDikvcsgirrlKRHEVEFDNGKTER-FD 337
Cdd:pfam13738 197 -------PSYSLSPDT------LNRLEELV---KNGKIKAHFNAEVKEITEVD----------VSYKVHTEDGRKVTsND 250

                         330       340       350
                  ....*....|....*....|....*....|.
gi 75161591   338 AIILATGYKSNVpSWLKeNKMFS-KKDGFPI 367
Cdd:pfam13738 251 DPILATGYHPDL-SFLK-KGLFElDEDGRPV 279
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
33-228 1.63e-20

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 91.33  E-value: 1.63e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLWQLKtydrlhlhlpkqfcelPIIPFPGdFPTYPTKQQFIEYLEDY 112
Cdd:COG0492   4 VIIGAGPAGLTAAIYAARAGLKTLVIEGGEPGGQLATTK----------------EIENYPG-FPEGISGPELAERLREQ 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 113 ARRFDikPEF-NQTVESAAFDEnlGMWRVTSvgeEGTTEYVCRWLVAATGenAEPVVPRFEGMDKFAAAGVvkHTCHYKT 191
Cdd:COG0492  67 AERFG--AEIlLEEVTSVDKDD--GPFRVTT---DDGTEYEAKAVIIATG--AGPRKLGLPGEEEFEGRGV--SYCATCD 135

                       170       180       190
                ....*....|....*....|....*....|....*..
gi 75161591 192 GGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVR 228
Cdd:COG0492 136 GFFFRGKDVVVVGGGDSALEEALYLTKFASKVTLIHR 172
IucD COG3486
Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism] ...
 35-353 4.52e-16

Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442709 [Multi-domain]  Cd Length: 440  Bit Score: 79.44  E-value: 4.52e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  35 VGAGPSGLATAACLKE-RGITSVLLERSNCIAslWQ---------------------------------LKTYDRLHLHL 80
Cdd:COG3486  12 IGIGPFNLGLAALLDElPDLDALFLERKPEFD--WHpgmllegatlqvpflkdlvtladptspfsflnyLKEHGRLYDFY 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  81 pkqfcelpiipFPGDFptYPTKQQFIEYLEDYARRFDiKPEFNQTVESAAFDENLGMWRVTSVGEEGTTE-YVCRWLVAA 159
Cdd:COG3486  90 -----------NRENF--FPLRREYNDYCRWAAEQLD-NVRFGTEVEAVEYDDDAGAFRVTVRDGTGEREtYRARNLVLG 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 160 TGenAEPVVPrfEGMDKFAAAGVVkHTCHYKTG-GDF-AGKRVLVVGCGNSGMEVCLDL----CNFGAQPSLVVRDAvHV 233
Cdd:COG3486 156 TG--TRPYLP--ECFRGLPGERVF-HSSEYLHRkEDLqAAKRVTVVGSGQSAAEIFLDLlrrqDGPGAELTWVTRSP-GF 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 234 LPREmlgTSTFGLSMFLLKWlpirlVDRFllvvsrFILGDTTllglnRPRLGPlELKNISGktpVLDVGTLAKI------ 307
Cdd:COG3486 230 FPLD---YSKFTNEIFSPEY-----VDYF------YALPEEV-----RDRLLA-EQKLLYK---GISPDLINEIydllye 286

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 75161591 308 -----KTGDIKVCSGiRRLK-------RHEVEFDNGKTE-----RFDAIILATGYKSNVPSWL 353
Cdd:COG3486 287 rsvggDPPRVRLLPN-SEVTaveraggGYRLTLRHLETGerfelETDAVVLATGYRPRLPAFL 348
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 99-346 1.45e-15

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 77.24  E-value: 1.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    99 YPTKQQFIEYLEDYARRFDIKPEFNQTVESAAFDE--NLGMWRVTSVGEEGT-TEYVCRWLVAATGenAEPVVPRFegmd 175
Cdd:pfam13434  91 FPSRREFNDYLQWAASHLPNRLRFGQEVESVEPDAerGEPLLRVRVRDADGEeTTFLARNLVLGTG--GEPYIPEC---- 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   176 kFAAAGVVKHTCHY--KTGGDFAGKRVLVVGCGNSGMEVCLDLCNFG--AQPSLVVRDAvHVLPREmlgTSTFGLSMF-- 249
Cdd:pfam13434 165 -ARGGERVFHSSEYleRIDRLAAKKRIAVVGSGQSAAEIFRDLLRRGpaYELTWVTRSP-NFFPLD---DSPFVNEIFsp 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   250 --------LLKWLPIRLVDRFLLVVSRFILGDT-----------TLLGLNRPRLGPLelknisgkTPVLDVGtlakiKTG 310
Cdd:pfam13434 240 eyvdyfysLPEDTRRALLREQKGTNYDGIDPSLieeiyrllyeqRVDGDPRHRLLPN--------REVQSAE-----RVG 306

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 75161591   311 DIKVCSGIRRLKRHEVEfdngkTERFDAIILATGYK 346
Cdd:pfam13434 307 DGGVELTLRDGEQGREE-----TLETDVVVLATGYR 337
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 33-216 3.05e-13

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 71.05  E-value: 3.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVLLERSNCIASLW--------------------QLKTYDRLHLHLPKQ---FCELPI 89
Cdd:PLN02172  14 AVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWvytpksesdplsldptrsivHSSVYESLRTNLPREcmgYRDFPF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   90 IPFPGDFP----TYPTKQQFIEYLEDYARRFDIKPEFNQTVESAAFDENLGMWRVTSVGEEGTTEY-VCRWLVAATGENA 164
Cdd:PLN02172  94 VPRFDDESrdsrRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVEPVDGKWRVQSKNSGGFSKDeIFDAVVVCNGHYT 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 75161591  165 EPVVPRFEGMDKFAAAGVvkHTCHYKTGGDFAGKRVLVVGCGNSGMEVCLDL 216
Cdd:PLN02172 174 EPNVAHIPGIKSWPGKQI--HSHNYRVPDPFKNEVVVVIGNFASGADISRDI 223
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 33-228 1.89e-09

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 58.48  E-value: 1.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591    33 VIVGAGPSGLATAACLKERGITSVLLER-SNCiaslwqlkTYDRlhlhlpkqfCELP--IIPFPGDFPTYPTKQQFIEYL 109
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQLGGKVTLIEDeGTC--------PYGG---------CVLSkaLLGAAEAPEIASLWADLYKRK 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   110 EDYARRFDIKPEFNQTVESAAFDENLGMWRVTSVGEEGTTEYVCRWLVAATGenAEPVVPRFEGMDKFAAAGVvkHTCHY 189
Cdd:pfam07992  67 EEVVKKLNNGIEVLLGTEVVSIDPGAKKVVLEELVDGDGETITYDRLVIATG--ARPRLPPIPGVELNVGFLV--RTLDS 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 75161591   190 KTGG--DFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVR 228
Cdd:pfam07992 143 AEALrlKLLPKRVVVVGGGYIGVELAAALAKLGKEVTLIEA 183
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 33-161 3.95e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 51.48  E-value: 3.95e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSN---------CIAS----------LWQL-----KTYDRLHLHLPKQFCELP 88
Cdd:COG0654   7 LIVGGGPAGLALALALARAGIRVTVVERAPpprpdgrgiALSPrslellrrlgLWDRllargAPIRGIRVRDGSDGRVLA 86

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 75161591  89 IIPFP-GDFPTYPT-KQQFIE-YLEDYARRFDIKPEFNQTVESAAFDENlgmwRVTSVGEEGTTEyVCRWLVAATG 161
Cdd:COG0654  87 RFDAAeTGLPAGLVvPRADLErALLEAARALGVELRFGTEVTGLEQDAD----GVTVTLADGRTL-RADLVVGADG 157
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 14-65 6.23e-07

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 51.41  E-value: 6.23e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75161591   14 AHDHRGMTSPRRICVVtgpvIVGAGPSGLATAACLKERGITSVLLE---------RSNCIA 65
Cdd:PRK08132  12 PHADQDADDPARHPVV----VVGAGPVGLALAIDLAQQGVPVVLLDdddtlstgsRAICFA 68
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
33-236 1.71e-06

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 49.75  E-value: 1.71e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERG----ITsvLLERSNCIAslwqlktYDRLHLhlPKQFC-ELPiipfPGDFPTYPtkqqfie 107
Cdd:COG1251   5 VIIGAGMAGVRAAEELRKLDpdgeIT--VIGAEPHPP-------YNRPPL--SKVLAgETD----EEDLLLRP------- 62

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 108 ylEDYARRFDIKPEFNQTVESAAFDENlgmwRVTSvgEEGTT-EYvcRWLVAATGenAEPVVPRFEGMDkfaAAGVVkht 186
Cdd:COG1251  63 --ADFYEENGIDLRLGTRVTAIDRAAR----TVTL--ADGETlPY--DKLVLATG--SRPRVPPIPGAD---LPGVF--- 124

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 75161591 187 cHYKTGGDF--------AGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAvHVLPR 236
Cdd:COG1251 125 -TLRTLDDAdalraalaPGKRVVVIGGGLIGLEAAAALRKRGLEVTVVERAP-RLLPR 180
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 33-62 2.62e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 45.98  E-value: 2.62e-05
                        10        20        30
                ....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSN 62
Cdd:COG1232   5 AVIGGGIAGLTAAYRLAKAGHEVTVLEASD 34
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
37-176 4.52e-05

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 44.96  E-value: 4.52e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  37 AGPSGLATAACLKERGITSVLLERS--------------NCIASLWQLKTYDRLHLHLPKQFCELP---IIPFPGDFPTY 99
Cdd:COG0644   1 AGPAGSAAARRLARAGLSVLLLEKGsfpgdkicgggllpRALEELEPLGLDEPLERPVRGARFYSPggkSVELPPGRGGG 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 75161591 100 PT--KQQFIEYLEDYARRFDIKPEFNQTVESAAFDEnlGMWRVTSVGEEgttEYVCRWLVAATGenAEPVVPRFEGMDK 176
Cdd:COG0644  81 YVvdRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDD--GRVVVRTGDGE---EIRADYVVDADG--ARSLLARKLGLKR 152
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 100-349 6.36e-05

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 44.80  E-value: 6.36e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 100 PTKQQFIEYLEDYARRFDIKPEFNQTVESAAFDENlgmwRVTsvGEEGTTE-YvcRWLVAATGenAEPVVPRFEGMDkfa 178
Cdd:COG0446  33 KDPEDLLVRTPESFERKGIDVRTGTEVTAIDPEAK----TVT--LRDGETLsY--DKLVLATG--ARPRPPPIPGLD--- 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 179 AAGVvkHTCHYKTGGD--------FAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVRDAvHVLPR---EMlgtstfglS 247
Cdd:COG0446 100 LPGV--FTLRTLDDADalrealkeFKGKRAVVIGGGPIGLELAEALRKRGLKVTLVERAP-RLLGVldpEM--------A 168

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 248 MFLLKWLPIRLVDrfllvvsrFILGDTtllglnrprlgpleLKNISGKtpvldvgtlakiktgdikvcsgirrlKRHEVE 327
Cdd:COG0446 169 ALLEEELREHGVE--------LRLGET--------------VVAIDGD--------------------------DKVAVT 200

                       250       260
                ....*....|....*....|..
gi 75161591 328 FDNGKTERFDAIILATGYKSNV 349
Cdd:COG0446 201 LTDGEEIPADLVVVAPGVRPNT 222
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
34-64 1.06e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 40.21  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 75161591    34 IVGAGPSGLATAACLKERGITSVLLERSNCI 64
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRL 31
PRK10262 PRK10262
thioredoxin reductase; Provisional
 33-228 1.08e-04

thioredoxin reductase; Provisional


Pssm-ID: 182343 [Multi-domain]  Cd Length: 321  Bit Score: 43.90  E-value: 1.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVL---LERSNCIASLWQLKTYdrlhlhlpkqfcelpiipfPGDfPTYPTKQQFIEYL 109
Cdd:PRK10262  10 LILGSGPAGYTAAVYAARANLQPVLitgMEKGGQLTTTTEVENW-------------------PGD-PNDLTGPLLMERM 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  110 EDYARRFDIKPEFNQTvesAAFDENLGMWRVTsvGEEGttEYVCRWLVAATGENAepvvpRFEGM---DKFAAAGVvkHT 186
Cdd:PRK10262  70 HEHATKFETEIIFDHI---NKVDLQNRPFRLT--GDSG--EYTCDALIIATGASA-----RYLGLpseEAFKGRGV--SA 135

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 75161591  187 CHYKTGGDFAGKRVLVVGCGNSGMEVCLDLCNFGAQPSLVVR 228
Cdd:PRK10262 136 CATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHR 177
PRK06126 PRK06126
hypothetical protein; Provisional
 25-98 1.52e-04

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 43.83  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591   25 RICVVTGPVIVGAGPSGLATAACLKERGITSVLLERS-----NCIASLWQLKT---YDRLHLHLPKQFCelpiiPFPGDF 96
Cdd:PRK06126   3 ENTSETPVLIVGGGPVGLALALDLGRRGVDSILVERKdgtafNPKANTTSARSmehFRRLGIADEVRSA-----GLPVDY 77


                 ..
gi 75161591   97 PT 98
Cdd:PRK06126  78 PT 79
PRK09126 PRK09126
FAD-dependent hydroxylase;
33-61 1.38e-03

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 40.70  E-value: 1.38e-03
                         10        20
                 ....*....|....*....|....*....
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVLLERS 61
Cdd:PRK09126   7 VVVGAGPAGLSFARSLAGSGLKVTLIERQ 35
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 33-62 1.39e-03

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 40.60  E-value: 1.39e-03
                        10        20        30
                ....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSN 62
Cdd:COG1233   7 VVIGAGIGGLAAAALLARAGYRVTVLEKND 36
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 33-60 1.48e-03

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 40.46  E-value: 1.48e-03
                          10        20
                  ....*....|....*....|....*...
gi 75161591    33 VIVGAGPSGLATAACLKERGITSVLLER 60
Cdd:pfam01266   3 VVIGGGIVGLSTAYELARRGLSVTLLER 30
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 33-62 1.70e-03

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 40.17  E-value: 1.70e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVLLERSN 62
Cdd:PRK08243   6 AIIGAGPAGLLLGQLLHLAGIDSVVLERRS 35
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 33-60 1.99e-03

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 40.00  E-value: 1.99e-03
                          10        20
                  ....*....|....*....|....*...
gi 75161591    33 VIVGAGPSGLATAACLKERGITSVLLER 60
Cdd:pfam01494   5 LIVGGGPAGLMLALLLARAGVRVVLVER 32
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
33-62 2.02e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 40.29  E-value: 2.02e-03
                        10        20        30
                ....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSN 62
Cdd:COG1231  11 VIVGAGLAGLAAARELRKAGLDVTVLEARD 40
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 33-172 2.16e-03

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 39.79  E-value: 2.16e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLERSnciaslwqlktyDRLHLHLPKQFCELpiipfpgdfptyptkqqfieyLEDY 112
Cdd:COG0446 128 VVIGGGPIGLELAEALRKRGLKVTLVERA------------PRLLGVLDPEMAAL---------------------LEEE 174

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591 113 ARRFDIKPEFNQTVESAAFDENLGmwrvtsVGEEGTTEYVCRWLVAATGenaepVVPRFE 172
Cdd:COG0446 175 LREHGVELRLGETVVAIDGDDKVA------VTLTDGEEIPADLVVVAPG-----VRPNTE 223
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
33-60 2.38e-03

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 39.89  E-value: 2.38e-03
                        10        20
                ....*....|....*....|....*...
gi 75161591  33 VIVGAGPSGLATAACLKERGITSVLLER 60
Cdd:COG0665   6 VVIGGGIAGLSTAYHLARRGLDVTVLER 33
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
33-60 2.71e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 39.89  E-value: 2.71e-03
                         10        20
                 ....*....|....*....|....*...
gi 75161591   33 VIVGAGPSGLATAACLKERGITSVLLER 60
Cdd:PRK06183  14 VIVGAGPVGLTLANLLGQYGVRVLVLER 41
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
32-60 4.19e-03

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 39.33  E-value: 4.19e-03
                        10        20
                ....*....|....*....|....*....
gi 75161591  32 PVIVGAGPSGLATAACLKERGITSVLLER 60
Cdd:COG2509  33 VVIVGAGPAGLFAALELAEAGLKPLVLER 61
NAD_bind_Leu_Phe_Val_DH cd01075
NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine ...
 175-229 4.59e-03

NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Amino acid dehydrogenase (DH) is a widely distributed family of enzymes that catalyzes the oxidative deamination of an amino acid to its keto acid and ammonia with concomitant reduction of NADP+. For example, leucine DH catalyzes the reversible oxidative deamination of L-leucine and several other straight or branched chain amino acids to the corresponding 2-oxoacid derivative. Amino acid DH -like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.


Pssm-ID: 133444  Cd Length: 200  Bit Score: 37.96  E-value: 4.59e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 75161591 175 DKFAAAGV---VKHTCHYKTGGD-FAGKRVLVVGCGNSGMEVCLDLCNFGAQpsLVVRD 229
Cdd:cd01075   2 SPPTAYGVflgMKAAAEHLLGTDsLEGKTVAVQGLGKVGYKLAEHLLEEGAK--LIVAD 58
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
 195-216 5.12e-03

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 38.99  E-value: 5.12e-03
                         10        20
                 ....*....|....*....|..
gi 75161591  195 FAGKRVLVVGCGNSGMEVCLDL 216
Cdd:PRK15317 349 FKGKRVAVIGGGNSGVEAAIDL 370
murD PRK14106
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
 194-222 6.65e-03

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional


Pssm-ID: 184511 [Multi-domain]  Cd Length: 450  Bit Score: 38.41  E-value: 6.65e-03
                         10        20
                 ....*....|....*....|....*....
gi 75161591  194 DFAGKRVLVVGCGNSGMEVCLDLCNFGAQ 222
Cdd:PRK14106   2 ELKGKKVLVVGAGVSGLALAKFLKKLGAK 30
COG3919 COG3919
Predicted ATP-dependent carboligase, ATP-grasp superfamily [General function prediction only];
30-119 7.48e-03

Predicted ATP-dependent carboligase, ATP-grasp superfamily [General function prediction only];


Pssm-ID: 443124 [Multi-domain]  Cd Length: 382  Bit Score: 38.37  E-value: 7.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75161591  30 TGPVIVGAGPSGLATAACLKERGITSVLLERSNCIASLWQlKTYDRLHlhlpkqfcelpIIPFPGDFPtyptkQQFIEYL 109
Cdd:COG3919   6 FRVVVLGGDINALAVARSLGEAGVRVIVVDRDPLGPAARS-RYVDEVV-----------VVPDPGDDP-----EAFVDAL 68

                        90
                ....*....|
gi 75161591 110 EDYARRFDIK 119
Cdd:COG3919  69 LELAERHGPD 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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