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Conserved domains on  [gi|81894490|sp|Q7TNI7|]
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RecName: Full=Interleukin-17F; Short=IL-17F; Flags: Precursor

Protein Classification

interleukin-17 family protein( domain architecture ID 10532846)

interleukin-17 (IL-17) family protein such as IL-17A, a key cytokine that links T cell activation to neutrophil mobilization and activation, and IL-25, also known as IL-7E, which induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IL17 pfam06083
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
 75-153 6.01e-38

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


:

Pssm-ID: 461823  Cd Length: 81  Bit Score: 124.69  E-value: 6.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81894490    75 RSSSPWDYNITRDPHRFPSEIAEAQCRHSGCIN-AQGQEDSTMNSVAIQQEILVLRREPQ-GCSNSFRLEKMLLKVGCTC 152
Cdd:pfam06083   1 RSLSPWTYRIDHDPNRYPQTIAEARCLCSGCINpATGQEDRSLNSVPIYQEILVLRRESCaGCRYSYRLEYETVTVGCTC 80


                  .
gi 81894490   153 V 153
Cdd:pfam06083  81 V 81
 
Name Accession Description Interval E-value
IL17 pfam06083
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
 75-153 6.01e-38

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


Pssm-ID: 461823  Cd Length: 81  Bit Score: 124.69  E-value: 6.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81894490    75 RSSSPWDYNITRDPHRFPSEIAEAQCRHSGCIN-AQGQEDSTMNSVAIQQEILVLRREPQ-GCSNSFRLEKMLLKVGCTC 152
Cdd:pfam06083   1 RSLSPWTYRIDHDPNRYPQTIAEARCLCSGCINpATGQEDRSLNSVPIYQEILVLRRESCaGCRYSYRLEYETVTVGCTC 80


                  .
gi 81894490   153 V 153
Cdd:pfam06083  81 V 81
 
Name Accession Description Interval E-value
IL17 pfam06083
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
 75-153 6.01e-38

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


Pssm-ID: 461823  Cd Length: 81  Bit Score: 124.69  E-value: 6.01e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81894490    75 RSSSPWDYNITRDPHRFPSEIAEAQCRHSGCIN-AQGQEDSTMNSVAIQQEILVLRREPQ-GCSNSFRLEKMLLKVGCTC 152
Cdd:pfam06083   1 RSLSPWTYRIDHDPNRYPQTIAEARCLCSGCINpATGQEDRSLNSVPIYQEILVLRRESCaGCRYSYRLEYETVTVGCTC 80


                  .
gi 81894490   153 V 153
Cdd:pfam06083  81 V 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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