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Conserved domains on  [gi|1179699154|sp|Q6P5W5|]
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RecName: Full=Zinc transporter ZIP4; AltName: Full=Solute carrier family 39 member 4; AltName: Full=Zrt- and Irt-like protein 4; Short=ZIP-4; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ZIP4_domain pfam18292
Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present ...
46-196 3.66e-40

Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present in Homo sapiens and Mus musculus. ZIP4 is a zinc transporter that allows uptake of the essential nutrient zinc. The domain is found before the N-terminal of ZIP Zinc transporter domain (Pfam: PF02535).


:

Pssm-ID: 465698  Cd Length: 170  Bit Score: 144.52  E-value: 3.66e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154  46 GLLNTLADRVHCA------NGPCGKCLSVEDALGLGepegSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLW 119
Cdd:pfam18292   1 SLINTLLERVHCAertagtQGPCGKCLTPDDLLALA----RGGDPEDVLSEEVFQRLSAALLLYLSNPEGTCTSIRAGRW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 120 ASHADHLLALL-----------ESPKALTPG-LSWLLQRMQaRAAGQTPKMACVDIPQLLEEAVGAG------APGSAGG 181
Cdd:pfam18292  77 ASRADHFLYKLylhsllslrqdEDSEALSLGeLERLLQRIQ-QHYRPSNSQACVDAPQLLEEANIAApgspgaDENTLPR 155
                         170
                  ....*....|....*
gi 1179699154 182 VLAALLDHVRSGSCF 196
Cdd:pfam18292 156 VLAAIIDHVLQGSCF 170
Zip pfam02535
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
328-638 5.15e-37

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


:

Pssm-ID: 396884 [Multi-domain]  Cd Length: 325  Bit Score: 140.97  E-value: 5.15e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 328 LYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGAVTGDAVLHLTPKVLG-LHTHSEEGLSPQPTWRLLAM 406
Cdd:pfam02535   5 IYAIFAILIISLIGGLLPLLVPKISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALEaLESLCLSDHGWHFPFAGLIV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 407 LAGLYAFFLFENLFNLLLPRDPEDLEDGPcghsSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEP 486
Cdd:pfam02535  85 LLGFLLVLLVEKLLTYYKHRPTPGPADNS----HSHLATVKSVSNVEVTESEEGEDHGHLHGHDDDSDELLHKGHQGPSD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 487 RRLSPE---------LRLLPYMITLGDAVHNFADGLAVGaaFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQ 557
Cdd:pfam02535 161 SIHEQSdedgeplasQRVRAILLELGIILHSFFEGLALG--VSSSSDTGISLFIAILFHKIPEGLGLGAILLQAGFSRKK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 558 ALLLNLASALTAFAGLYVALAVGVSEES------EAWILAVATGLFLYVALCDMLPAMLKVRDPRPWlLFLLHNVGLLGG 631
Cdd:pfam02535 239 AVLLALLFALTTPLGILIGIGVSSIGNSpgaditSGILLAFSAGTFLYVALVELLPHELLRNKSSEK-LSLLQLLALLLG 317

                  ....*..
gi 1179699154 632 WTVLLLL 638
Cdd:pfam02535 318 FALMALL 324
 
Name Accession Description Interval E-value
ZIP4_domain pfam18292
Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present ...
46-196 3.66e-40

Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present in Homo sapiens and Mus musculus. ZIP4 is a zinc transporter that allows uptake of the essential nutrient zinc. The domain is found before the N-terminal of ZIP Zinc transporter domain (Pfam: PF02535).


Pssm-ID: 465698  Cd Length: 170  Bit Score: 144.52  E-value: 3.66e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154  46 GLLNTLADRVHCA------NGPCGKCLSVEDALGLGepegSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLW 119
Cdd:pfam18292   1 SLINTLLERVHCAertagtQGPCGKCLTPDDLLALA----RGGDPEDVLSEEVFQRLSAALLLYLSNPEGTCTSIRAGRW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 120 ASHADHLLALL-----------ESPKALTPG-LSWLLQRMQaRAAGQTPKMACVDIPQLLEEAVGAG------APGSAGG 181
Cdd:pfam18292  77 ASRADHFLYKLylhsllslrqdEDSEALSLGeLERLLQRIQ-QHYRPSNSQACVDAPQLLEEANIAApgspgaDENTLPR 155
                         170
                  ....*....|....*
gi 1179699154 182 VLAALLDHVRSGSCF 196
Cdd:pfam18292 156 VLAAIIDHVLQGSCF 170
Zip pfam02535
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
328-638 5.15e-37

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


Pssm-ID: 396884 [Multi-domain]  Cd Length: 325  Bit Score: 140.97  E-value: 5.15e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 328 LYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGAVTGDAVLHLTPKVLG-LHTHSEEGLSPQPTWRLLAM 406
Cdd:pfam02535   5 IYAIFAILIISLIGGLLPLLVPKISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALEaLESLCLSDHGWHFPFAGLIV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 407 LAGLYAFFLFENLFNLLLPRDPEDLEDGPcghsSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEP 486
Cdd:pfam02535  85 LLGFLLVLLVEKLLTYYKHRPTPGPADNS----HSHLATVKSVSNVEVTESEEGEDHGHLHGHDDDSDELLHKGHQGPSD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 487 RRLSPE---------LRLLPYMITLGDAVHNFADGLAVGaaFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQ 557
Cdd:pfam02535 161 SIHEQSdedgeplasQRVRAILLELGIILHSFFEGLALG--VSSSSDTGISLFIAILFHKIPEGLGLGAILLQAGFSRKK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 558 ALLLNLASALTAFAGLYVALAVGVSEES------EAWILAVATGLFLYVALCDMLPAMLKVRDPRPWlLFLLHNVGLLGG 631
Cdd:pfam02535 239 AVLLALLFALTTPLGILIGIGVSSIGNSpgaditSGILLAFSAGTFLYVALVELLPHELLRNKSSEK-LSLLQLLALLLG 317

                  ....*..
gi 1179699154 632 WTVLLLL 638
Cdd:pfam02535 318 FALMALL 324
ZupT COG0428
Zinc transporter ZupT [Inorganic ion transport and metabolism];
497-637 4.10e-21

Zinc transporter ZupT [Inorganic ion transport and metabolism];


Pssm-ID: 440197 [Multi-domain]  Cd Length: 243  Bit Score: 92.94  E-value: 4.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 497 PYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYV- 575
Cdd:COG0428   104 GLLIALGITLHNFPEGLAIGVAFAADPALGLALALAIALHNIPEGLAVAAPLRAAGYSRRKALLLGLLSGLVEPLGALLg 183
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1179699154 576 ALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLhnVGLLGGWTVLLL 637
Cdd:COG0428   184 YLLLSLSPALLPYLLAFAAGAMLYVVVDELIPEAHREGHSRLATLGLL--LGFLLMMLLDVL 243
 
Name Accession Description Interval E-value
ZIP4_domain pfam18292
Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present ...
46-196 3.66e-40

Zinc transporter ZIP4 domain; This domain is found in ZRT1-IRT1-like protein 4 (ZIP4) present in Homo sapiens and Mus musculus. ZIP4 is a zinc transporter that allows uptake of the essential nutrient zinc. The domain is found before the N-terminal of ZIP Zinc transporter domain (Pfam: PF02535).


Pssm-ID: 465698  Cd Length: 170  Bit Score: 144.52  E-value: 3.66e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154  46 GLLNTLADRVHCA------NGPCGKCLSVEDALGLGepegSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLW 119
Cdd:pfam18292   1 SLINTLLERVHCAertagtQGPCGKCLTPDDLLALA----RGGDPEDVLSEEVFQRLSAALLLYLSNPEGTCTSIRAGRW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 120 ASHADHLLALL-----------ESPKALTPG-LSWLLQRMQaRAAGQTPKMACVDIPQLLEEAVGAG------APGSAGG 181
Cdd:pfam18292  77 ASRADHFLYKLylhsllslrqdEDSEALSLGeLERLLQRIQ-QHYRPSNSQACVDAPQLLEEANIAApgspgaDENTLPR 155
                         170
                  ....*....|....*
gi 1179699154 182 VLAALLDHVRSGSCF 196
Cdd:pfam18292 156 VLAAIIDHVLQGSCF 170
Zip pfam02535
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
328-638 5.15e-37

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


Pssm-ID: 396884 [Multi-domain]  Cd Length: 325  Bit Score: 140.97  E-value: 5.15e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 328 LYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGAVTGDAVLHLTPKVLG-LHTHSEEGLSPQPTWRLLAM 406
Cdd:pfam02535   5 IYAIFAILIISLIGGLLPLLVPKISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALEaLESLCLSDHGWHFPFAGLIV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 407 LAGLYAFFLFENLFNLLLPRDPEDLEDGPcghsSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEP 486
Cdd:pfam02535  85 LLGFLLVLLVEKLLTYYKHRPTPGPADNS----HSHLATVKSVSNVEVTESEEGEDHGHLHGHDDDSDELLHKGHQGPSD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 487 RRLSPE---------LRLLPYMITLGDAVHNFADGLAVGaaFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQ 557
Cdd:pfam02535 161 SIHEQSdedgeplasQRVRAILLELGIILHSFFEGLALG--VSSSSDTGISLFIAILFHKIPEGLGLGAILLQAGFSRKK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 558 ALLLNLASALTAFAGLYVALAVGVSEES------EAWILAVATGLFLYVALCDMLPAMLKVRDPRPWlLFLLHNVGLLGG 631
Cdd:pfam02535 239 AVLLALLFALTTPLGILIGIGVSSIGNSpgaditSGILLAFSAGTFLYVALVELLPHELLRNKSSEK-LSLLQLLALLLG 317

                  ....*..
gi 1179699154 632 WTVLLLL 638
Cdd:pfam02535 318 FALMALL 324
ZupT COG0428
Zinc transporter ZupT [Inorganic ion transport and metabolism];
497-637 4.10e-21

Zinc transporter ZupT [Inorganic ion transport and metabolism];


Pssm-ID: 440197 [Multi-domain]  Cd Length: 243  Bit Score: 92.94  E-value: 4.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1179699154 497 PYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYV- 575
Cdd:COG0428   104 GLLIALGITLHNFPEGLAIGVAFAADPALGLALALAIALHNIPEGLAVAAPLRAAGYSRRKALLLGLLSGLVEPLGALLg 183
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1179699154 576 ALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLhnVGLLGGWTVLLL 637
Cdd:COG0428   184 YLLLSLSPALLPYLLAFAAGAMLYVVVDELIPEAHREGHSRLATLGLL--LGFLLMMLLDVL 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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