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Conserved domains on  [gi|74746942|sp|Q5VTH2|]
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RecName: Full=Protein Flattop; AltName: Full=Cilia- and flagella-associated protein 126

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Flattop cd23705
protein Flattop and similar proteins; Protein Flattop, also known as cilia- and ...
 2-74 1.72e-40

protein Flattop and similar proteins; Protein Flattop, also known as cilia- and flagella-associated protein 126 (CFAP126), or flagellum-associated protein 126 (FAP126), acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. It regulates basal body docking and cilia formation in multiciliated human lung cells. It also modulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.


:

Pssm-ID: 467918  Cd Length: 73  Bit Score: 131.16  E-value: 1.72e-40
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74746942   2 ATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKI 74
Cdd:cd23705   1 SRNFSANQYEDAFKPKRLQNWEVPKWFKERPKTREGRTQIIADDRGHLLPGVPRSKKSPWGNFVGTWDLPKKI 73
 
Name Accession Description Interval E-value
Flattop cd23705
protein Flattop and similar proteins; Protein Flattop, also known as cilia- and ...
 2-74 1.72e-40

protein Flattop and similar proteins; Protein Flattop, also known as cilia- and flagella-associated protein 126 (CFAP126), or flagellum-associated protein 126 (FAP126), acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. It regulates basal body docking and cilia formation in multiciliated human lung cells. It also modulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.


Pssm-ID: 467918  Cd Length: 73  Bit Score: 131.16  E-value: 1.72e-40
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74746942   2 ATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKI 74
Cdd:cd23705   1 SRNFSANQYEDAFKPKRLQNWEVPKWFKERPKTREGRTQIIADDRGHLLPGVPRSKKSPWGNFVGTWDLPKKI 73
 
Name Accession Description Interval E-value
Flattop cd23705
protein Flattop and similar proteins; Protein Flattop, also known as cilia- and ...
 2-74 1.72e-40

protein Flattop and similar proteins; Protein Flattop, also known as cilia- and flagella-associated protein 126 (CFAP126), or flagellum-associated protein 126 (FAP126), acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. It regulates basal body docking and cilia formation in multiciliated human lung cells. It also modulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.


Pssm-ID: 467918  Cd Length: 73  Bit Score: 131.16  E-value: 1.72e-40
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74746942   2 ATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKI 74
Cdd:cd23705   1 SRNFSANQYEDAFKPKRLQNWEVPKWFKERPKTREGRTQIIADDRGHLLPGVPRSKKSPWGNFVGTWDLPKKI 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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