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Conserved domains on  [gi|74672087|sp|Q4WRE2|]
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RecName: Full=SWR1-complex protein 5

Protein Classification

BCNT domain-containing protein( domain architecture ID 10540970)

BCNT domain-containing protein similar to human craniofacial development protein 1 (CFDP1), also called Bucentaur (BCNT), that may play a role during embryogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 297-357 2.44e-26

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


:

Pssm-ID: 462213  Cd Length: 71  Bit Score: 99.98  E-value: 2.44e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74672087   297 GPKINTVEKSRLDWAAYVDQAGIKDELKEHSKAKEGFLGRMDFLNRVVAKREEERRNARLK 357
Cdd:pfam07572  11 KKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
DNA_pol_phi super family cl47903
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 11-97 3.40e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


The actual alignment was detected with superfamily member pfam04931:

Pssm-ID: 461488  Cd Length: 765  Bit Score: 42.61  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74672087    11 DLDFDNEQYDSAEDEDFQLDPDQEDADLTGSDSDDEATEPAAKRR-------KTGPTKAATEDQELDS--GDEAMI---- 77
Cdd:pfam04931 644 EDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDELRaklaealGEHGDDADDDDSDSDEdmDDEQMMalde 723

                          90       100
                  ....*....|....*....|....*..
gi 74672087    78 -------QKVKARKEGKQKGKKSQGTA 97
Cdd:pfam04931 724 qlaeifkERKKAGNDKKKKKKDAKENV 750
 
Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 297-357 2.44e-26

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


Pssm-ID: 462213  Cd Length: 71  Bit Score: 99.98  E-value: 2.44e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74672087   297 GPKINTVEKSRLDWAAYVDQAGIKDELKEHSKAKEGFLGRMDFLNRVVAKREEERRNARLK 357
Cdd:pfam07572  11 KKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 11-97 3.40e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 42.61  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74672087    11 DLDFDNEQYDSAEDEDFQLDPDQEDADLTGSDSDDEATEPAAKRR-------KTGPTKAATEDQELDS--GDEAMI---- 77
Cdd:pfam04931 644 EDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDELRaklaealGEHGDDADDDDSDSDEdmDDEQMMalde 723

                          90       100
                  ....*....|....*....|....*..
gi 74672087    78 -------QKVKARKEGKQKGKKSQGTA 97
Cdd:pfam04931 724 qlaeifkERKKAGNDKKKKKKDAKENV 750
 
Name Accession Description Interval E-value
BCNT pfam07572
Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) ...
 297-357 2.44e-26

Bucentaur or craniofacial development; Bucentaur or craniofacial development protein 1 (BCNT) in ruminents has a different domain architecture to that in mouse and human. For this reason it has been used as a model for molecular evolution. Both bovine and human BCNTs are phosphorylated by casein kinase II in vitro.


Pssm-ID: 462213  Cd Length: 71  Bit Score: 99.98  E-value: 2.44e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74672087   297 GPKINTVEKSRLDWAAYVDQAGIKDELKEHSKAKEGFLGRMDFLNRVVAKREEERRNARLK 357
Cdd:pfam07572  11 KKKLSTLEKSKLDWASFKDKEGIEEELELHNKGKDGYLEKQDFLQRVDLRRFEIEREARLA 71
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 11-97 3.40e-04

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 42.61  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74672087    11 DLDFDNEQYDSAEDEDFQLDPDQEDADLTGSDSDDEATEPAAKRR-------KTGPTKAATEDQELDS--GDEAMI---- 77
Cdd:pfam04931 644 EDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVDEIDELRaklaealGEHGDDADDDDSDSDEdmDDEQMMalde 723

                          90       100
                  ....*....|....*....|....*..
gi 74672087    78 -------QKVKARKEGKQKGKKSQGTA 97
Cdd:pfam04931 724 qlaeifkERKKAGNDKKKKKKDAKENV 750
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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