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Conserved domains on  [gi|75319537|sp|Q40235|]
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RecName: Full=Receptor-like protein Cf-9; Flags: Precursor

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 13746049)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 70-778 1.16e-72

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 257.47  E-value: 1.16e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   70 SWNKSTSCCSWDGVHCDETTgQVIALDLRCSQLQGKFhsNSSLFQLSNLKRLDLSFNNFTGSLISPKFGEFSNLTHLDLS 149
Cdd:PLN00113  50 NWNSSADVCLWQGITCNNSS-RVVSIDLSGKNISGKI--SSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLS 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  150 HSSFTGLIPSeichlsklhvlricdqyglslvpynfelllKNLTQLRELNLESVNISSTIPSN--FSSHLTTLQLSGTEL 227
Cdd:PLN00113 127 NNNFTGSIPR------------------------------GSIPNLETLDLSNNMLSGEIPNDigSFSSLKVLDLGGNVL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  228 HGILPERVFHLSNLQSLHLSVNpQLTVRFPTtKWNSSASLMTLYVDSVNIADRIPKSFSHLTSLHELYMGRCNLSGPIPK 307
Cdd:PLN00113 177 VGKIPNSLTNLTSLEFLTLASN-QLVGQIPR-ELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPS 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  308 PLWNLTNIVFLHLGDNHLEGPISHfTIFEKLKRLSLvnnnfdggleflsfntqlerlDLSSNSLTGPIPSNISGLQNLEC 387
Cdd:PLN00113 255 SLGNLKNLQYLFLYQNKLSGPIPP-SIFSLQKLISL---------------------DLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  388 LYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSKtlsavtlkqnklkgripnsllnqknlqllllsHNNisg 467
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGK--------------------------------HNN--- 357

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  468 hissaicnlktLILLDLGSNNLEGTIPQCVVERNeYLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMI 547
Cdd:PLN00113 358 -----------LTVLDLSTNNLTGEIPEGLCSSG-NLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFT 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  548 NCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPI-KSSGNTNLfmglQILDLSSNGFSGNLPERilgnLQT 626
Cdd:PLN00113 426 KLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLpDSFGSKRL----ENLDLSRNQFSGAVPRK----LGS 497

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  627 MKEIdestgfpeyisdpydiyynylttistkgqdydsvrildsnMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEG 706
Cdd:PLN00113 498 LSEL----------------------------------------MQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSG 537

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75319537  707 HIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRG 778
Cdd:PLN00113 538 QIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 29-86 1.03e-05

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


:

Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 43.05  E-value: 1.03e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537    29 PEDQALSLLQFKNMFTINPNAsdycydirtyvdiqsyprTLSWN-KSTSCCSWDGVHCD 86
Cdd:pfam08263   1 LNDDGQALLAFKSSLNDPPGA------------------LSSWNsSSSDPCSWTGVTCD 41
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-778 1.16e-72

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 257.47  E-value: 1.16e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   70 SWNKSTSCCSWDGVHCDETTgQVIALDLRCSQLQGKFhsNSSLFQLSNLKRLDLSFNNFTGSLISPKFGEFSNLTHLDLS 149
Cdd:PLN00113  50 NWNSSADVCLWQGITCNNSS-RVVSIDLSGKNISGKI--SSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLS 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  150 HSSFTGLIPSeichlsklhvlricdqyglslvpynfelllKNLTQLRELNLESVNISSTIPSN--FSSHLTTLQLSGTEL 227
Cdd:PLN00113 127 NNNFTGSIPR------------------------------GSIPNLETLDLSNNMLSGEIPNDigSFSSLKVLDLGGNVL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  228 HGILPERVFHLSNLQSLHLSVNpQLTVRFPTtKWNSSASLMTLYVDSVNIADRIPKSFSHLTSLHELYMGRCNLSGPIPK 307
Cdd:PLN00113 177 VGKIPNSLTNLTSLEFLTLASN-QLVGQIPR-ELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPS 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  308 PLWNLTNIVFLHLGDNHLEGPISHfTIFEKLKRLSLvnnnfdggleflsfntqlerlDLSSNSLTGPIPSNISGLQNLEC 387
Cdd:PLN00113 255 SLGNLKNLQYLFLYQNKLSGPIPP-SIFSLQKLISL---------------------DLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  388 LYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSKtlsavtlkqnklkgripnsllnqknlqllllsHNNisg 467
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGK--------------------------------HNN--- 357

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  468 hissaicnlktLILLDLGSNNLEGTIPQCVVERNeYLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMI 547
Cdd:PLN00113 358 -----------LTVLDLSTNNLTGEIPEGLCSSG-NLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFT 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  548 NCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPI-KSSGNTNLfmglQILDLSSNGFSGNLPERilgnLQT 626
Cdd:PLN00113 426 KLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLpDSFGSKRL----ENLDLSRNQFSGAVPRK----LGS 497

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  627 MKEIdestgfpeyisdpydiyynylttistkgqdydsvrildsnMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEG 706
Cdd:PLN00113 498 LSEL----------------------------------------MQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSG 537

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75319537  707 HIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRG 778
Cdd:PLN00113 538 QIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
146-533 8.83e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 98.85  E-value: 8.83e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 146 LDLSHSSFTGLIPSEICHLSKLHVLRICDQYGLSLVPYNFELLLKNLTQLRELNLESVNISSTIPSNFSSHLTTLQLSGT 225
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 226 ELHGILPERVFHLSNLQSLHLSVNPQLTvrfpttkwnSSASLMTLYVDSVNIADrIPKSFSHLTSLHELYMGRCNLSgPI 305
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSGNEELS---------NLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DL 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 306 PKPLWNLTNIVFLHLGDNHLEG---PISHFTifeKLKRLSLVNNNFDGGLEFLSFNTQLERLDLSSNSLTgPIPSNISGL 382
Cdd:COG4886 152 PEPLGNLTNLKSLDLSNNQLTDlpeELGNLT---NLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANL 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 383 QNLECLYLSSNHLNgSIPsWIFSLPSLVELDLSNNTFSGKIQEFKSKTLSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSH 462
Cdd:COG4886 228 TNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLL 305

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75319537 463 NNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSKNRLSGTINTTFSVGNILRVISL 533
Cdd:COG4886 306 LLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLE 376
LRR_8 pfam13855
Leucine rich repeat;
693-752 5.77e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 5.77e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   693 GLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHL 752
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 188-420 2.16e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 53.51  E-value: 2.16e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 188 LLKNLTQLRELNLESVN--------ISSTIPSNFSshLTTLQLSGTELHGI------LPERVFHLSNLQSLHLSVN---P 250
Cdd:cd00116  18 LLPKLLCLQVLRLEGNTlgeeaakaLASALRPQPS--LKELCLSLNETGRIprglqsLLQGLTKGCGLQELDLSDNalgP 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 251 QLTVRFPTTKwnSSASLMTLYVDSVNIADRIPKSF-----SHLTSLHELYMGRCNLSG----PIPKPLWNLTNIVFLHLG 321
Cdd:cd00116  96 DGCGVLESLL--RSSSLQELKLNNNGLGDRGLRLLakglkDLPPALEKLVLGRNRLEGasceALAKALRANRDLKELNLA 173

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 322 DNHLEGP-ISH----FTIFEKLKRLSLVNNNF--DGGL---EFLSFNTQLERLDLSSNSLTGPI-----PSNISGLQNLE 386
Cdd:cd00116 174 NNGIGDAgIRAlaegLKANCNLEVLDLNNNGLtdEGASalaETLASLKSLEVLNLGDNNLTDAGaaalaSALLSPNISLL 253

                       250       260       270
                ....*....|....*....|....*....|....*...
gi 75319537 387 CLYLSSNHLN----GSIPSWIFSLPSLVELDLSNNTFS 420
Cdd:cd00116 254 TLSLSCNDITddgaKDLAEVLAEKESLLELDLRGNKFG 291
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 29-86 1.03e-05

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 43.05  E-value: 1.03e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537    29 PEDQALSLLQFKNMFTINPNAsdycydirtyvdiqsyprTLSWN-KSTSCCSWDGVHCD 86
Cdd:pfam08263   1 LNDDGQALLAFKSSLNDPPGA------------------LSSWNsSSSDPCSWTGVTCD 41
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 70-778 1.16e-72

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 257.47  E-value: 1.16e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   70 SWNKSTSCCSWDGVHCDETTgQVIALDLRCSQLQGKFhsNSSLFQLSNLKRLDLSFNNFTGSLISPKFGEFSNLTHLDLS 149
Cdd:PLN00113  50 NWNSSADVCLWQGITCNNSS-RVVSIDLSGKNISGKI--SSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLS 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  150 HSSFTGLIPSeichlsklhvlricdqyglslvpynfelllKNLTQLRELNLESVNISSTIPSN--FSSHLTTLQLSGTEL 227
Cdd:PLN00113 127 NNNFTGSIPR------------------------------GSIPNLETLDLSNNMLSGEIPNDigSFSSLKVLDLGGNVL 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  228 HGILPERVFHLSNLQSLHLSVNpQLTVRFPTtKWNSSASLMTLYVDSVNIADRIPKSFSHLTSLHELYMGRCNLSGPIPK 307
Cdd:PLN00113 177 VGKIPNSLTNLTSLEFLTLASN-QLVGQIPR-ELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPS 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  308 PLWNLTNIVFLHLGDNHLEGPISHfTIFEKLKRLSLvnnnfdggleflsfntqlerlDLSSNSLTGPIPSNISGLQNLEC 387
Cdd:PLN00113 255 SLGNLKNLQYLFLYQNKLSGPIPP-SIFSLQKLISL---------------------DLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  388 LYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSKtlsavtlkqnklkgripnsllnqknlqllllsHNNisg 467
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGK--------------------------------HNN--- 357

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  468 hissaicnlktLILLDLGSNNLEGTIPQCVVERNeYLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMI 547
Cdd:PLN00113 358 -----------LTVLDLSTNNLTGEIPEGLCSSG-NLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFT 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  548 NCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPI-KSSGNTNLfmglQILDLSSNGFSGNLPERilgnLQT 626
Cdd:PLN00113 426 KLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLpDSFGSKRL----ENLDLSRNQFSGAVPRK----LGS 497

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  627 MKEIdestgfpeyisdpydiyynylttistkgqdydsvrildsnMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEG 706
Cdd:PLN00113 498 LSEL----------------------------------------MQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSG 537

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75319537  707 HIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHLVGCIPKGKQFDSFGNTSYQGNDGLRG 778
Cdd:PLN00113 538 QIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
146-533 8.83e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 98.85  E-value: 8.83e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 146 LDLSHSSFTGLIPSEICHLSKLHVLRICDQYGLSLVPYNFELLLKNLTQLRELNLESVNISSTIPSNFSSHLTTLQLSGT 225
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 226 ELHGILPERVFHLSNLQSLHLSVNPQLTvrfpttkwnSSASLMTLYVDSVNIADrIPKSFSHLTSLHELYMGRCNLSgPI 305
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSGNEELS---------NLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DL 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 306 PKPLWNLTNIVFLHLGDNHLEG---PISHFTifeKLKRLSLVNNNFDGGLEFLSFNTQLERLDLSSNSLTgPIPSNISGL 382
Cdd:COG4886 152 PEPLGNLTNLKSLDLSNNQLTDlpeELGNLT---NLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANL 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 383 QNLECLYLSSNHLNgSIPsWIFSLPSLVELDLSNNTFSGKIQEFKSKTLSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSH 462
Cdd:COG4886 228 TNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLL 305

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75319537 463 NNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSKNRLSGTINTTFSVGNILRVISL 533
Cdd:COG4886 306 LLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLE 376
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
108-509 2.26e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 88.45  E-value: 2.26e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 108 SNSSLFQLSNLKRLDLSFNNFTGSLISPKFGEFSNLTHLDLSHSSFTGLIPSEICHLSKLHVLRICDQYGLSLVPYNFEL 187
Cdd:COG4886  13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 188 llKNLTQLRELNLesvniSSTIPSNFSSHLTTLQLSGTELHGiLPERVFHLSNLQSLHLSVNpqltvrfpttkwnssasl 267
Cdd:COG4886  93 --GDLTNLTELDL-----SGNEELSNLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNN------------------ 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 268 mtlyvdsvNIADrIPKSFSHLTSLHELYMGRCNLSGpIPKPLWNLTNIVFLHLGDNHLEGPISHFTIFEKLKRLSLVNNN 347
Cdd:COG4886 147 --------QLTD-LPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQ 216

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 348 FDGGLEFLSFNTQLERLDLSSNSLTgPIPSnISGLQNLECLYLSSNHLNgSIPSwIFSLPSLVELDLSNNTFSGKIQEFK 427
Cdd:COG4886 217 LTDLPEPLANLTNLETLDLSNNQLT-DLPE-LGNLTNLEELDLSNNQLT-DLPP-LANLTNLKTLDLSNNQLTDLKLKEL 292

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 428 SKTLSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHL 507
Cdd:COG4886 293 ELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLL 372


                ..
gi 75319537 508 DL 509
Cdd:COG4886 373 GL 374
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
241-723 2.66e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.29  E-value: 2.66e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 241 LQSLHLSVNPQLTVRFPTTKWNSSASLMTLYVDSVNIADRIPKSFSHLTSLHELYMGRCNLSGPIPKPLWNLTNIVFLHL 320
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 321 GDNHLEGPISHFTIFEKLKRLSLVNNNFDGGLeflsfnTQLERLDLSSNSLTGpIPSNISGLQNLECLYLSSNHLNgSIP 400
Cdd:COG4886  81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNL------TNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DLP 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 401 SWIFSLPSLVELDLSNNTFSGkiqefksktlsavtlkqnklkgripnsllnqknlqllllshnnisghISSAICNLKTLI 480
Cdd:COG4886 153 EPLGNLTNLKSLDLSNNQLTD-----------------------------------------------LPEELGNLTNLK 185

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 481 LLDLGSNNLEgTIPqCVVERNEYLSHLDLSKNRLSgtinttfsvgnilrvislhgnkltgKVPRSMINCKYLTLLDLGNN 560
Cdd:COG4886 186 ELDLSNNQIT-DLP-EPLGNLTNLEELDLSGNQLT-------------------------DLPEPLANLTNLETLDLSNN 238

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 561 MLNDtFPnWLGYLFQLKILSLRSNKLHGPIKSSGNTNlfmgLQILDLSSNGFSGNLPERILGNLQTMKEIDESTGFPEYI 640
Cdd:COG4886 239 QLTD-LP-ELGNLTNLEELDLSNNQLTDLPPLANLTN----LKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLE 312

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 641 SDPYDIYYNYLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLES 720
Cdd:COG4886 313 LLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLL 392


                ...
gi 75319537 721 LDL 723
Cdd:COG4886 393 LLT 395
PLN03150 PLN03150
hypothetical protein; Provisional
 673-786 1.04e-15

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 81.40  E-value: 1.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  673 INLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHL 752
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 75319537  753 VGCIPK--GKQFDSFGNTSYQGNDGLRGFPLSKLCG 786
Cdd:PLN03150 503 SGRVPAalGGRLLHRASFNFTDNAGLCGIPGLRACG 538
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
425-752 1.03e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.12  E-value: 1.03e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 425 EFKSKTLSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSHNNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYL 504
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 505 SHLDLSKNRLSGTINTtfsvgniLRVISLHGNKLTgKVPRSMINCKYLTLLDLGNNMLNDtFPNWLGYLFQLKILSLRSN 584
Cdd:COG4886  99 TELDLSGNEELSNLTN-------LESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTD-LPEPLGNLTNLKSLDLSNN 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 585 KLHG-PIKSSGNTNLfmglQILDLSSNGFSgNLPErILGNLQTMKEIDestgfpeyisdpydIYYNYLTTISTKGQDYDS 663
Cdd:COG4886 170 QLTDlPEELGNLTNL----KELDLSNNQIT-DLPE-PLGNLTNLEELD--------------LSGNQLTDLPEPLANLTN 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 664 VRILDsnmiinLSKNRFEgHIPSIiGDLVGLRTLNLSHNVLEgHIPASFqNLSVLESLDLSSNKISGEIPQQLASLTFLE 743
Cdd:COG4886 230 LETLD------LSNNQLT-DLPEL-GNLTNLEELDLSNNQLT-DLPPLA-NLTNLKTLDLSNNQLTDLKLKELELLLGLN 299


                ....*....
gi 75319537 744 VLNLSHNHL 752
Cdd:COG4886 300 SLLLLLLLL 308
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
463-752 1.58e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 70.35  E-value: 1.58e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 463 NNISGHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKV 542
Cdd:COG4886   9 TLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLG 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 543 PRSMINCKYLTLLDLGNNmlndtfpNWLGYLFQLKILSLRSNKLHG-PIKSSGNTNLfmglQILDLSSNGFSgNLPERiL 621
Cdd:COG4886  89 LTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDlPEELANLTNL----KELDLSNNQLT-DLPEP-L 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 622 GNLQTMKEIDestgfpeyisdpydIYYNYLTTISTKGQDYDSVRILdsnmiiNLSKNRFEgHIPSIIGDLVGLRTLNLSH 701
Cdd:COG4886 156 GNLTNLKSLD--------------LSNNQLTDLPEELGNLTNLKEL------DLSNNQIT-DLPEPLGNLTNLEELDLSG 214

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 75319537 702 NVLEgHIPASFQNLSVLESLDLSSNKISgEIPqQLASLTFLEVLNLSHNHL 752
Cdd:COG4886 215 NQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQL 262
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
366-752 3.26e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.58  E-value: 3.26e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 366 LSSNSLTGPIPSNISGLQNLECLYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSKTLSAVTLKQNKLKGRI 445
Cdd:COG4886   2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 446 PNSLLNQKNLQLLLLSHNNISGHISSAICNLKTLILLDLGSNNLEgTIPQCvVERNEYLSHLDLSKNRLSgTINTTFSVG 525
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLT-DLPEE-LANLTNLKELDLSNNQLT-DLPEPLGNL 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 526 NILRVISLHGNKLTGkVPRSMINCKYLTLLDLGNNMLNDtFPNWLGYLFQLKILSLRSNKLH---GPIKSSGNtnlfmgL 602
Cdd:COG4886 159 TNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQLTdlpEPLANLTN------L 230

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 603 QILDLSSNGFSgNLPEriLGNLQTMKEIdestgfpeyisdpyDIYYNYLTTISTKGQdydsvriLDSNMIINLSKNRFEG 682
Cdd:COG4886 231 ETLDLSNNQLT-DLPE--LGNLTNLEEL--------------DLSNNQLTDLPPLAN-------LTNLKTLDLSNNQLTD 286

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 683 HIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHL 752
Cdd:COG4886 287 LKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
PLN03150 PLN03150
hypothetical protein; Provisional
 364-448 2.49e-11

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 67.15  E-value: 2.49e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  364 LDLSSNSLTGPIPSNISGLQNLECLYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKIQEFKSK--TLSAVTLKQNKL 441
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQltSLRILNLNGNSL 502


                 ....*..
gi 75319537  442 KGRIPNS 448
Cdd:PLN03150 503 SGRVPAA 509
PLN03150 PLN03150
hypothetical protein; Provisional
 66-182 3.16e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 60.60  E-value: 3.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   66 PRTLSWNkSTSCCS----WDGVHC--DETTGQ--VIALDLRCSQLQGKFHSNSSlfQLSNLKRLDLSFNNFTGSlISPKF 137
Cdd:PLN03150 387 PLRFGWN-GDPCVPqqhpWSGADCqfDSTKGKwfIDGLGLDNQGLRGFIPNDIS--KLRHLQSINLSGNSIRGN-IPPSL 462

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 75319537  138 GEFSNLTHLDLSHSSFTGLIPSEICHLSKLHVLRICDQYGLSLVP 182
Cdd:PLN03150 463 GSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 208-489 6.16e-09

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 59.03  E-value: 6.16e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 208 TIPSNFSSHLTTLQLSGTELHGILP-----ERVFHLSN-LQSLHLSVNP---QLTVRFPTTKWNSSASLMTLYVDSVNIA 278
Cdd:COG5238 114 TPPPDLRRIMAKTLEDSLILYLALPrrinlIQVLKDPLgGNAVHLLGLAarlGLLAAISMAKALQNNSVETVYLGCNQIG 193

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 279 D----RIPKSFSHLTSLHELYMGRcnlsgpipkplwnltnivfLHLGDNHLEGPISHFTIFEKLKRLSLVNNNF-DGGL- 352
Cdd:COG5238 194 DegieELAEALTQNTTVTTLWLKR-------------------NPIGDEGAEILAEALKGNKSLTTLDLSNNQIgDEGVi 254

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 353 ---EFLSFNTQLERLDLSSNSLTGP----IPSNISGLQNLECLYLSSNHLNGsiPSWIFSLPSL------VELDLSNNTF 419
Cdd:COG5238 255 alaEALKNNTTVETLYLSGNQIGAEgaiaLAKALQGNTTLTSLDLSVNRIGD--EGAIALAEGLqgnktlHTLNLAYNGI 332

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 75319537 420 SGKIQEFKSKTLSA-VTLKQNKLKGripnsllnqknlqllllshNNISGHISSAICNL----KTLILLDLGSNNL 489
Cdd:COG5238 333 GAQGAIALAKALQEnTTLHSLDLSD-------------------NQIGDEGAIALAKYlegnTTLRELNLGKNNI 388
LRR_8 pfam13855
Leucine rich repeat;
693-752 5.77e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 5.77e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   693 GLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKISGEIPQQLASLTFLEVLNLSHNHL 752
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 360-423 5.90e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 56.36  E-value: 5.90e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75319537  360 QLERLDLSSNSLTGPIPSNISGLQNLECLYLSSNHLNGSIPSWIFSLPSLVELDLSNNTFSGKI 423
Cdd:PLN03150 443 HLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRV 506
PLN03150 PLN03150
hypothetical protein; Provisional
 503-593 6.42e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 56.36  E-value: 6.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  503 YLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLR 582
Cdd:PLN03150 419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLN 498

                         90
                 ....*....|.
gi 75319537  583 SNKLHGPIKSS 593
Cdd:PLN03150 499 GNSLSGRVPAA 509
LRR_8 pfam13855
Leucine rich repeat;
359-417 1.57e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 1.57e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537   359 TQLERLDLSSNSLTGPIPSNISGLQNLECLYLSSNHLNGSIPSWIFSLPSLVELDLSNN 417
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 188-420 2.16e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 53.51  E-value: 2.16e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 188 LLKNLTQLRELNLESVN--------ISSTIPSNFSshLTTLQLSGTELHGI------LPERVFHLSNLQSLHLSVN---P 250
Cdd:cd00116  18 LLPKLLCLQVLRLEGNTlgeeaakaLASALRPQPS--LKELCLSLNETGRIprglqsLLQGLTKGCGLQELDLSDNalgP 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 251 QLTVRFPTTKwnSSASLMTLYVDSVNIADRIPKSF-----SHLTSLHELYMGRCNLSG----PIPKPLWNLTNIVFLHLG 321
Cdd:cd00116  96 DGCGVLESLL--RSSSLQELKLNNNGLGDRGLRLLakglkDLPPALEKLVLGRNRLEGasceALAKALRANRDLKELNLA 173

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 322 DNHLEGP-ISH----FTIFEKLKRLSLVNNNF--DGGL---EFLSFNTQLERLDLSSNSLTGPI-----PSNISGLQNLE 386
Cdd:cd00116 174 NNGIGDAgIRAlaegLKANCNLEVLDLNNNGLtdEGASalaETLASLKSLEVLNLGDNNLTDAGaaalaSALLSPNISLL 253

                       250       260       270
                ....*....|....*....|....*....|....*...
gi 75319537 387 CLYLSSNHLN----GSIPSWIFSLPSLVELDLSNNTFS 420
Cdd:cd00116 254 TLSLSCNDITddgaKDLAEVLAEKESLLELDLRGNKFG 291
PLN03150 PLN03150
hypothetical protein; Provisional
 467-546 1.31e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.13  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  467 GHISSAICNLKTLILLDLGSNNLEGTIPQCVVERNEyLSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSM 546
Cdd:PLN03150 432 GFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITS-LEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAAL 510
LRR_8 pfam13855
Leucine rich repeat;
671-728 3.79e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.82  E-value: 3.79e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 75319537   671 MIINLSKNRFEGHIPSIIGDLVGLRTLNLSHNVLEGHIPASFQNLSVLESLDLSSNKI 728
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 29-86 1.03e-05

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 43.05  E-value: 1.03e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537    29 PEDQALSLLQFKNMFTINPNAsdycydirtyvdiqsyprTLSWN-KSTSCCSWDGVHCD 86
Cdd:pfam08263   1 LNDDGQALLAFKSSLNDPPGA------------------LSSWNsSSSDPCSWTGVTCD 41
PLN03150 PLN03150
hypothetical protein; Provisional
 318-407 1.04e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.04  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  318 LHLGDNHLEGPI-SHFTIFEKLKRLSLVNNNFDGGLEfLSFN--TQLERLDLSSNSLTGPIPSNISGLQNLECLYLSSNH 394
Cdd:PLN03150 423 LGLDNQGLRGFIpNDISKLRHLQSINLSGNSIRGNIP-PSLGsiTSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501

                         90
                 ....*....|...
gi 75319537  395 LNGSIPSWIFSLP 407
Cdd:PLN03150 502 LSGRVPAALGGRL 514
PLN03150 PLN03150
hypothetical protein; Provisional
 555-628 3.05e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.50  E-value: 3.05e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 75319537  555 LDLGNNMLNDTFPNWLGYLFQLKILSLRSNKLHGPIKSSGNTnlFMGLQILDLSSNGFSGNLPERiLGNLQTMK 628
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGS--ITSLEVLDLSYNSFNGSIPES-LGQLTSLR 493
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 312-515 7.30e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.78  E-value: 7.30e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 312 LTNIVFLHLGDNHLEGpISHFTIFEKLKRLSLVNNNFDGgLEFLSFNTQLERLDLSSNSLTgpIPSNISGLQNLECLYLS 391
Cdd:cd21340   1 LKRITHLYLNDKNITK-IDNLSLCKNLKVLYLYDNKITK-IENLEFLTNLTHLYLQNNQIE--KIENLENLVNLKKLYLG 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 392 SNH------LNGsipswifsLPSLVELDLSN-NTFSGKIQEFKSKTLSAVtlkQNKLkgRIPNsllnqknlqlllLSHNN 464
Cdd:cd21340  77 GNRisvvegLEN--------LTNLEELHIENqRLPPGEKLTFDPRSLAAL---SNSL--RVLN------------ISGNN 131

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 75319537 465 ISghISSAICNLKTLILLDLGSNNLEGTIPQCVVERN-EYLSHLDLSKNRLS 515
Cdd:cd21340 132 ID--SLEPLAPLRNLEQLDASNNQISDLEELLDLLSSwPSLRELDLTGNPVC 181
PLN03150 PLN03150
hypothetical protein; Provisional
 605-711 7.68e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 46.35  E-value: 7.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  605 LDLSSNGFSGNLPERIlGNLQTMKEIDestgfpeyisdpydiyynyLTTISTKGQDYDSVRILDSNMIINLSKNRFEGHI 684
Cdd:PLN03150 423 LGLDNQGLRGFIPNDI-SKLRHLQSIN-------------------LSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSI 482

                         90       100
                 ....*....|....*....|....*..
gi 75319537  685 PSIIGDLVGLRTLNLSHNVLEGHIPAS 711
Cdd:PLN03150 483 PESLGQLTSLRILNLNGNSLSGRVPAA 509
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 318-564 8.42e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 45.42  E-value: 8.42e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 318 LHLGDNHLEG-------PISHFTIFEKLKRLSLVNNNFD----GGLEFLSFNTQLERLDLSSNSL-TGPIPSNISGLQ-- 383
Cdd:cd00116  56 LCLSLNETGRiprglqsLLQGLTKGCGLQELDLSDNALGpdgcGVLESLLRSSSLQELKLNNNGLgDRGLRLLAKGLKdl 135

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 384 --NLECLYLSSNHLNG----SIPSWIFSLPSLVELDLSNNtfsgKIQEFKSKTLsAVTLKQNklkgripnsllnqknlql 457
Cdd:cd00116 136 ppALEKLVLGRNRLEGasceALAKALRANRDLKELNLANN----GIGDAGIRAL-AEGLKAN------------------ 192

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 458 lllshnnisghissaiCNLKTLILLDLGSNNLEGTIPQCVVERNEYLSHLDLSKNRLSGTINTTFSVGNI-----LRVIS 532
Cdd:cd00116 193 ----------------CNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASALLspnisLLTLS 256

                       250       260       270
                ....*....|....*....|....*....|....*.
gi 75319537 533 LHGNKLT----GKVPRSMINCKYLTLLDLGNNMLND 564
Cdd:cd00116 257 LSCNDITddgaKDLAEVLAEKESLLELDLRGNKFGE 292
LRR_8 pfam13855
Leucine rich repeat;
504-562 2.09e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537   504 LSHLDLSKNRLSGTINTTFSVGNILRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNML 562
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 694-752 2.64e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 2.64e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 75319537 694 LRTLNLSHNVLEghIPASFQNLSVLESLDLSSNKIS--GEIPQQLASLTFLEVLNLSHNHL 752
Cdd:cd21340 122 LRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGNPV 180
PLN03150 PLN03150
hypothetical protein; Provisional
 482-571 6.58e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 43.27  E-value: 6.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  482 LDLGSNNLEGTIPQcVVERNEYLSHLDLSKNRLSGTINTTFsvGNI--LRVISLHGNKLTGKVPRSMINCKYLTLLDLGN 559
Cdd:PLN03150 423 LGLDNQGLRGFIPN-DISKLRHLQSINLSGNSIRGNIPPSL--GSItsLEVLDLSYNSFNGSIPESLGQLTSLRILNLNG 499

                         90
                 ....*....|..
gi 75319537  560 NMLNDTFPNWLG 571
Cdd:PLN03150 500 NSLSGRVPAALG 511
LRR_8 pfam13855
Leucine rich repeat;
337-395 8.02e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 8.02e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   337 KLKRLSLVNNNFDG-GLEFLSFNTQLERLDLSSNSLTGPIPSNISGLQNLECLYLSSNHL 395
Cdd:pfam13855   2 NLRSLDLSNNRLTSlDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 412-497 1.13e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  412 LDLSNNTFSGKIQEFKSKT--LSAVTLKQNKLKGRIPNSLLNQKNLQLLLLSHNNISGHISSAICNLKTLILLDLGSNNL 489
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLrhLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502


                 ....*...
gi 75319537  490 EGTIPQCV 497
Cdd:PLN03150 503 SGRVPAAL 510
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 378-584 1.30e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 1.30e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 378 NISGLQNLECLYLSSNHLNgSIPSwIFSLPSLVELDLSNNtfsgKIQefksktlsavtlkqnklkgRIPNsllnqknlql 457
Cdd:cd21340  19 NLSLCKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNN----QIE-------------------KIEN---------- 63

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 458 lllshnnisghissaICNLKTLILLDLGSNN---LEGtipqcvVERNEYLSHLDLSKNRL-SGT-----INTTFSVGNIL 528
Cdd:cd21340  64 ---------------LENLVNLKKLYLGGNRisvVEG------LENLTNLEELHIENQRLpPGEkltfdPRSLAALSNSL 122

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 75319537 529 RVISLHGNKLTGkvPRSMINCKYLTLLDLGNNMLND------TFPNWlgylFQLKILSLRSN 584
Cdd:cd21340 123 RVLNISGNNIDS--LEPLAPLRNLEQLDASNNQISDleelldLLSSW----PSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 220-327 1.95e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.73  E-value: 1.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537  220 LQLSGTELHGILPERVFHLSNLQSLHLSVNpqltvrfpttkwnssaslmtlyvdsvNIADRIPKSFSHLTSLHELYMGRC 299
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGN--------------------------SIRGNIPPSLGSITSLEVLDLSYN 476

                         90       100
                 ....*....|....*....|....*...
gi 75319537  300 NLSGPIPKPLWNLTNIVFLHLGDNHLEG 327
Cdd:PLN03150 477 SFNGSIPESLGQLTSLRILNLNGNSLSG 504
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 80-416 2.33e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 41.78  E-value: 2.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537    80 WDGVHcdETTGqvialdLRCSQLQGKfhsnsslfqlSNLKRL-DLSFNnftgslispkfgefSNLTHLDLSHSSFTGLIP 158
Cdd:PLN03210  627 WDGVH--SLTG------LRNIDLRGS----------KNLKEIpDLSMA--------------TNLETLKLSDCSSLVELP 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   159 SEICHLSKLHVLRICDQYGLSLVPYNFelllkNLTQLRELNLESVNISSTIPsNFSSHLTTLQLSGTELHGILPErvFHL 238
Cdd:PLN03210  675 SSIQYLNKLEDLDMSRCENLEILPTGI-----NLKSLYRLNLSGCSRLKSFP-DISTNISWLDLDETAIEEFPSN--LRL 746

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   239 SNLQSLHL--SVNPQLTVRF-PTTKWNS--SASLMTLYVDSVNIADRIPKSFSHLTSLHELYMGRCNLSGPIPkplwnlT 313
Cdd:PLN03210  747 ENLDELILceMKSEKLWERVqPLTPLMTmlSPSLTRLFLSDIPSLVELPSSIQNLHKLEHLEIENCINLETLP------T 820

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   314 NIVFLHLGDNHLEGpISHFTIFEKLK-RLSLVNNNFDGGLE---FLSFNTQLERLDLSSNSLTGPIPSNISGLQNLE--- 386
Cdd:PLN03210  821 GINLESLESLDLSG-CSRLRTFPDIStNISDLNLSRTGIEEvpwWIEKFSNLSFLDMNGCNNLQRVSLNISKLKHLEtvd 899

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 75319537   387 ---CLYLSSNHLNGS------IPSWIFS-LPSLVELDLSN 416
Cdd:PLN03210  900 fsdCGALTEASWNGSpsevamATDNIHSkLPSTVCINFIN 939
LRR_8 pfam13855
Leucine rich repeat;
116-167 3.76e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 3.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 75319537   116 SNLKRLDLSFNNFTGslISPK-FGEFSNLTHLDLSHSSFTGLIPSEICHLSKL 167
Cdd:pfam13855   1 PNLRSLDLSNNRLTS--LDDGaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSL 51
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 691-752 3.78e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.77  E-value: 3.78e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537 691 LVGLRTLNLSHN---VLEG----------HI--------------PASFQNLSV-LESLDLSSNKISgeIPQQLASLTFL 742
Cdd:cd21340  67 LVNLKKLYLGGNrisVVEGlenltnleelHIenqrlppgekltfdPRSLAALSNsLRVLNISGNNID--SLEPLAPLRNL 144

                        90
                ....*....|
gi 75319537 743 EVLNLSHNHL 752
Cdd:cd21340 145 EQLDASNNQI 154
LRR_8 pfam13855
Leucine rich repeat;
193-250 6.34e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 6.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 75319537   193 TQLRELNLESVNISSTIPSNFS--SHLTTLQLSGTELHGILPERVFHLSNLQSLHLSVNP 250
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKglSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_8 pfam13855
Leucine rich repeat;
528-586 7.96e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 7.96e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 75319537   528 LRVISLHGNKLTGKVPRSMINCKYLTLLDLGNNMLNDTFPNWLGYLFQLKILSLRSNKL 586
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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