|
Name |
Accession |
Description |
Interval |
E-value |
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
15-639 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 806.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNYPIDKMWLGTFHS 94
Cdd:COG0210 10 EQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLARGLWVGTFHS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 95 LSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEHKNIDIKEKPPKYFATVIDNYKNKGIFPQSV-KSSKGKKGEENI 173
Cdd:COG0210 90 LALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSLISRAKNEGLTPEELaELLAADPEWRAA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 174 AIIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDD 253
Cdd:COG0210 170 AELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRNLCVVGDDD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 254 QSIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEES 333
Cdd:COG0210 250 QSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYVAPDEEEEA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 334 VYVSDEIEKLISNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERI 413
Cdd:COG0210 330 RFVADEIRELHEEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANPDDDVALLRI 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 414 INVPKRGIGRTTLGKINSIARNNNISMFNAGSKMIQDS--TSKVNIEINEFIRKVHKWYNLKKEIDHIELTQLILEDSKY 491
Cdd:COG0210 410 LNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAglSGRAAKALRRFAELLEALRAAAERLPLEELLEALLDESGY 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 492 VEYLEQEeknsKNPENLNRLENIKEFIESLKDFE------NLEGFLEHVGLVMENISN-TNDESISLMTMHSAKGLEFDN 564
Cdd:COG0210 490 EEELREE----AGEEAERRLENLEELVDAAARFEernpgaSLEAFLEELALLSDLDAAdEDEDAVTLMTLHAAKGLEFPV 565
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1347645574 565 VFLAGWEEGVFPSMRSIDElgKKGLEEERRLAYVALTRARRKIHITYVnQNRYSYVSHDFNMPSRFIEELPKNLV 639
Cdd:COG0210 566 VFLVGLEEGLFPHQRSLDD--EEELEEERRLFYVAITRARERLYLTYA-ASRRLWGETQDNEPSRFLDELPEELL 637
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
15-737 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 708.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNYPIDKMWLGTFHS 94
Cdd:TIGR01073 8 EQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLGPVAEDIWISTFHS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 95 LSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEHKNIDIKEKPPKYFATVIDNYKNKGIFPQSVKSSKGKKGEENIA 174
Cdd:TIGR01073 88 MCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTILKDKNLDPKKFEPRSILGTISNAKNELLPPEDFAKEATNYFEKVVA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 175 IIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDDQ 254
Cdd:TIGR01073 168 EVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFRNLCVVGDADQ 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 255 SIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEESV 334
Cdd:TIGR01073 248 SIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYYEADTERDEAQ 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 335 YVSDEIEKLISN-KTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERI 413
Cdd:TIGR01073 328 FVAGEIDKLVKNgERKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRI 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 414 INVPKRGIGRTTLGKINSIARNNNISMFNAGSK--MIQDSTSKVNIEINEFIRKVHKWYNLKKEIDHIELTQLILEDSKY 491
Cdd:TIGR01073 408 INVPKRGIGASSLEKIVNYALELNISLFEAIGEidEIGGLAAKSANALLAFATMIENLRQQQEYLSPTELVEEVLDKSGY 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 492 VEYLEQEeknsKNPENLNRLENIKEFIESLKDFEN------LEGFLEHVGLVMEN-ISNTNDE--SISLMTMHSAKGLEF 562
Cdd:TIGR01073 488 REMLKAE----KTEEAQSRLENLDEFLSVTKEFEDesedksLIDFLTDLALVSDLdELEETEEggAVTLMTLHAAKGLEF 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 563 DNVFLAGWEEGVFPSMRSIDElgKKGLEEERRLAYVALTRARRKIHITYVnQNRYSYVSHDFNMPSRFIEELPKNLVNiN 642
Cdd:TIGR01073 564 PVVFLIGMEEGVFPHSRSLMD--EKELEEERRLAYVGITRAEEELYLTHA-TMRTLFGRIQMNPPSRFLNEIPAELLE-T 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 643 NSTYLSNNNFIDEFSQIENMdssfitPGRKRLLSRIKKEEDDWDFNQdyqsnsnateGSRVFHQKFGYGKIIFI--DGDK 720
Cdd:TIGR01073 640 ASTGRRTGATDPKGPSIRQA------GASRPTTSQPTAGGDTLSWAV----------GDRVNHKKWGIGTVVSVkgGGDD 703
|
730
....*....|....*....
gi 1347645574 721 AE--VDFEKSSQRKIFLKY 737
Cdd:TIGR01073 704 QEldIAFPSIGVKRLLAAF 722
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
16-721 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 602.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 16 QRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNYPIDKMWLGTFHSL 95
Cdd:PRK11773 14 QREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGTSQGGMWVGTFHGL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 96 SAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEHKNIDIKEKPPKYFATVIDNYKNKGIFPQSVKSSkGKKGEENIAI 175
Cdd:PRK11773 94 AHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAQWYINGQKDEGLRPQHIQSY-GDPVEQTWLK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 176 IYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDDQS 255
Cdd:PRK11773 173 IYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDTGKVMIVGDDDQS 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 256 IYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEESVY 335
Cdd:PRK11773 253 IYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISLYCAFNELDEARF 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 336 VSDEIEKLISNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERIIN 415
Cdd:PRK11773 333 VVERIKTWQDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIANRNDDAAFERVVN 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 416 VPKRGIGRTTLGKINSIARNNNISMFNAGSKMIQDS--TSKVNIEINEFIRKVHkwyNLKKEIDHIEL---TQLILEDSK 490
Cdd:PRK11773 413 TPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKvlAGRAASALQRFIELID---ALAQETADMPLheqTDRVIKDSG 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 491 YVEYLEQE--EKNSKNPENLNRLEN-IKEFI--ESLKDFENLEGFLEHVGL-VMENISNTNDESISLMTMHSAKGLEFDN 564
Cdd:PRK11773 490 LRAMYEQEkgEKGQARIENLEELVTaTRQFSypDEDEDLTPLQAFLSHAALeAGEGQADAHEDAVQLMTLHSAKGLEFPL 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 565 VFLAGWEEGVFPSMRSIDELGKkgLEEERRLAYVALTRARRKIHITYVNQNRYsYVSHDFNMPSRFIEELPKNLVninns 644
Cdd:PRK11773 570 VFIVGMEEGLFPSQMSLEEGGR--LEEERRLAYVGITRAMQKLTLTYAESRRL-YGKEVYHRPSRFIREIPEECV----- 641
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1347645574 645 tylsnnnfiDEFsqieNMDSSFITPGRKRLLSRIKKEEDDWDFNQdyqsnsnateGSRVFHQKFGYGKIIFIDGDKA 721
Cdd:PRK11773 642 ---------EEV----RLRATVSRPVSHQRMGTPAVEANDSGFKL----------GQRVRHPKFGEGTIVNFEGSGA 695
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
15-718 |
0e+00 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 559.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNYPIDKMWLGTFHS 94
Cdd:TIGR01075 8 KQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSARGMWIGTFHG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 95 LSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEHKNIDIKEKPPKYFATVIDNYKNKGIFPQSVkSSKGKKGEENIA 174
Cdd:TIGR01075 88 LAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAMWYINNQKDEGLRPSHI-QAFDNPVERTWI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 175 IIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDDQ 254
Cdd:TIGR01075 167 KIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMIVGDDDQ 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 255 SIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEESV 334
Cdd:TIGR01075 247 SIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFNELDEAR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 335 YVSDEIEKLISNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERII 414
Cdd:TIGR01075 327 FVVSRIKTWQRNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIANRNDDAAFERVI 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 415 NVPKRGIGRTTLGKINSIARNNNISMFNAGSKMIQDS--TSKVNIEINEFIRKVHKWYNLKKEIDHIELTQLILEDSKYV 492
Cdd:TIGR01075 407 NTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKvlAGRAASALQRFVELIEALANETADMPLHVQTDHVIKDSGLR 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 493 EYLEQE--EKNSKNPENLNRLENI-KEFI--ESLKDFENLEGFLEHVGL-VMENISNTNDESISLMTMHSAKGLEFDNVF 566
Cdd:TIGR01075 487 EMYQQEkgEKGQARIENLEELVTAtRQFSlpENDEDMTPLTAFLSHAALeAGEGQADAGQDAVQLMTLHSAKGLEFPLVF 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 567 LAGWEEGVFPSMRSIDELGkkGLEEERRLAYVALTRARRKIHITYVNQNRYsYVSHDFNMPSRFIEELPKNL---VNINN 643
Cdd:TIGR01075 567 LVGMEEGMFPSQMSLDEGG--RLEEERRLAYVGITRAMQKLTITYAETRRL-YGKEVYHIPSRFIRELPEEClheVRLRA 643
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1347645574 644 STYLSNNNfidefsqienmdssfitpgrKRLLSRIKKEEDDWDFNQdyqsnsnateGSRVFHQKFGYGKIIFIDG 718
Cdd:TIGR01075 644 QVSRPTNL--------------------GRVGTPSVDEINDAGFKL----------GQRVRHPKFGEGTIINAEG 688
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
15-635 |
2.30e-168 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 499.66 E-value: 2.30e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLlIEKLAFS-NQILAVTFTNKAASEMKIRVSNLLNYP-IDKMWLGTF 92
Cdd:TIGR01074 5 QQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYL-IQNCGYKaRNIAAVTFTNKAAREMKERVAKTLGKGeARGLTISTF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 93 HSLSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICeHKNIDIKEKPPKYFATVIDNYKNKGIFPQSVKSSKGKKGEEN 172
Cdd:TIGR01074 84 HTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELT-EGLIKDDKDLLDKLISTISNWKNDLLTPEQALASARGEREQT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 173 IAIIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDD 252
Cdd:TIGR01074 163 FAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFTVVGDD 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 253 DQSIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEE 332
Cdd:TIGR01074 243 DQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECNNEEHE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 333 SVYVSDEI--EKLIsNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLAL 410
Cdd:TIGR01074 323 AERIAGEIiaHKLV-NKTQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPDDDAAF 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 411 ERIINVPKRGIGRTTLGKINSIARNNNISMFNAGSKM--IQDSTSKVNIEINEFIRKVHKWYNLKKEIDHIELTQLILED 488
Cdd:TIGR01074 402 LRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMglLQTLSGRGYESLQRFTDWLVEIRRLAERSEPIEAVRSLIED 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 489 SKYVEYLEQEEKNSKNPEnlNRLENIKEFIESLKDFENLEGFLEHVGL-----------VME-NISNTNDESISLMTMHS 556
Cdd:TIGR01074 482 IDYENWLYETSPSPKAAE--MRMKNVNTLFSWFKEMLEGDEEDEPMTLtqvvtrltlrdMLErGEDEEELDQVQLMTLHA 559
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1347645574 557 AKGLEFDNVFLAGWEEGVFPSMRSIDElgkKGLEEERRLAYVALTRARRKIHITYVnQNRYSYVSHDFNMPSRFIEELP 635
Cdd:TIGR01074 560 SKGLEFPYVFIVGMEEGILPHQSSIEE---DNVEEERRLAYVGITRAQKELTFTLC-KERRQYGELVRPEPSRFLDELP 634
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
16-637 |
1.29e-121 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 379.18 E-value: 1.29e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 16 QRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNYPIDK-MWLGTFHS 94
Cdd:PRK10919 7 QQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARgLMISTFHT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 95 LSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEHKNIDIKEKPPKYFATvIDNYKNKGIFPQSVKSSKGKKGEENIA 174
Cdd:PRK10919 87 LGLDIIKREYAALGMKSNFSLFDDTDQLALLKELTEGLIEDDKVLLQQLIST-ISNWKNDLKTPAQAAAGAKGERDRIFA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 175 IIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDDQ 254
Cdd:PRK10919 166 HCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 255 SIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEESV 334
Cdd:PRK10919 246 SIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNEEHEAE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 335 YVSDE-IEKLISNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERI 413
Cdd:PRK10919 326 RVTGElIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRI 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 414 INVPKRGIGRTTLGKINSIARNNNISMFNAGSKM-IQDSTSKVNIE-INEFIRKVHKWYNLkKEIDHIELTQLILEDSKY 491
Cdd:PRK10919 406 VNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMgLSQTLSGRGYEsLTRFTHWLAEIQRL-AEREPVAAVRDLIHGIDY 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 492 VEYLEQEEKNSKNPEnlNRLENIKEFIESLKdfENLEG--FLEHVGL-----------VME-NISNTNDESISLMTMHSA 557
Cdd:PRK10919 485 ESWLYETSPSPKAAE--MRMKNVNQLFSWMT--EMLEGseLDEPMTLtqvvtrftlrdMMErGESEEELDQVQLMTLHAS 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 558 KGLEFDNVFLAGWEEGVFPSMRSIDElgkKGLEEERRLAYVALTRARRKIHITYVNQNRySYVSHDFNMPSRFIEELPKN 637
Cdd:PRK10919 561 KGLEFPYVYLVGMEEGLLPHQSSIDE---DNIDEERRLAYVGITRAQKELTFTLCKERR-QYGELVRPEPSRFLLELPQD 636
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
15-274 |
9.24e-96 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 298.00 E-value: 9.24e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLL-NYPIDKMWLGTFH 93
Cdd:pfam00580 4 EQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLgKAELSELNISTFH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 94 SLSAKILRAHAELVGLKSNFIIIDSDDQLKLIKQICEH--KNIDIKEKPPKYFATVIDNYKNKGIFPQSVKSSKGKKGEE 171
Cdd:pfam00580 84 SFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKdrLNLDPKLLRKLELKELISKAKNRLLSPEELQQGAADPRDK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 172 NIAIIYKLYQEELLRLNCVDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGD 251
Cdd:pfam00580 164 LAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFLVGD 243
|
250 260
....*....|....*....|...
gi 1347645574 252 DDQSIYSWRGADVNILLNFEKNF 274
Cdd:pfam00580 244 PDQSIYGFRGADIENILKFEKDF 266
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
15-610 |
3.68e-85 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 287.63 E-value: 3.68e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEK-LAFSnQILAVTFTNKAASEMKIRV----SNLLNYP------ 83
Cdd:COG1074 9 AQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERgLDPE-EILVVTFTRAAAAEMRERIrerlAEAADLEdpdlee 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 84 --------------IDKMWLGTFHSLSAKILRAHAELVGLKSNFIIIDsDDQLKLIKQICEhkniD-----IKEKPPKYF 144
Cdd:COG1074 88 lararrrlaralenLDRAAISTIHSFCQRLLREFAFEAGLDPNFELLD-DAEALLLEEAVD----DllreaYAPLDALAL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 145 ATVIDNY------------------------------------------KNKGIFPQSVKSSKGKKGEENIAI------I 176
Cdd:COG1074 163 ARLLDAFgrdddsleelllalyklrsrpdwleelaeldealealreallKAKEALAALREALAAAAAPLLAALlrllaaV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 177 YKLYQEELLRLNCVDFGDLILFCIKIFKENK--EVCSKYQNLFKFILVDEYQDINNVQ----QQWLEFFYQGHKNICCVG 250
Cdd:COG1074 243 LARYERRKRERGLLDFDDLLHRALRLLRDEDapWVAERLRERYRHILVDEFQDTSPLQweilRRLAGEALADGRTLFLVG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 251 DDDQSIYSWRGADVNILLNFEKNFSKPL---IIRLEQNYRSTKNILEC--ASF---------------LIAKNKGRYGK- 309
Cdd:COG1074 323 DPKQSIYRFRGADPELFLEARRALEGRVdgeRLTLTTNFRSTPEVVDAvnALFaqlmgagfgeipyepVEALRPGAYPAv 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 310 ELWS-DKDKGEKISIKgfwhtKEESVYVSDEIEKLISNKTPLSE---------IAILFRVSAHTRSFEDRFINLGLSYKI 379
Cdd:COG1074 403 ELWPlEPDDVSEEDAR-----EREARAVAARIRRLLAEGTTVEGggrpvrpgdIAVLVRTRSEAAAIARALKAAGIPVAA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 380 IGGLRFYERKEIRDVIAYLRLVHNLDDNLALERIINVPkrgIGRTTLGKINSIARNN-NISMFNAgskmIQDSTskvniE 458
Cdd:COG1074 478 SDRLSLFESPEVRDLLALLRALLNPEDDLALAAVLRSP---LFGLSDEDLAALAADRkGESLWEA----LRAYE-----R 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 459 INEFIRKVHKWYNLKKEIDHIELTQLILEDSKYVEYLeqeeknSKNPENLNRLEN---IKEFIESLKDFEN-----LEGF 530
Cdd:COG1074 546 LARALERLRALRELARRLGLAELLERLLEETGLLERL------LALPGGERRLANllhLDELLQLALEYEQtggpgLAGF 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 531 LEHVGLVMEN-------ISNTNDESISLMTMHSAKGLEFDNVFLAgweegvfpsmRSIDELGKKGLEEERRLAYVALTRA 603
Cdd:COG1074 620 LRWLERLIEDggdeekrRLESDADAVRIMTIHKSKGLEFPVVFLP----------ALRERARAEELAEELRLLYVALTRA 689
|
....*..
gi 1347645574 604 RRKIHIT 610
Cdd:COG1074 690 RDRLVLS 696
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
15-286 |
4.37e-75 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 240.50 E-value: 4.37e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLL-NYPIDKMWLGTFH 93
Cdd:cd17932 3 EQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLgEQLASGVWIGTFH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 94 SLSAKILRAHAelvglksnfiiidsddqlklikqicehknidikekppkyfatvidnyknkgifpqsvksskgkkgeeni 173
Cdd:cd17932 83 SFALRILRRYG--------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 174 aiiyklyqeellrlncvDFGDLILFCIKIFKENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDD 253
Cdd:cd17932 94 -----------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDDD 156
|
250 260 270
....*....|....*....|....*....|...
gi 1347645574 254 QSIYSWRGADVNILLNFEKNFSKPLIIRLEQNY 286
Cdd:cd17932 157 QSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
280-614 |
2.71e-65 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 221.51 E-value: 2.71e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 280 IRLEQNYRSTKNILECASFLIAKNKGRY----GKELWSDKDKGEKISIKGFWHTKEESVYVSDEIEKLISNKTPLSEIAI 355
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRAtiypKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 356 LFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERIINVPKRGIGRTTLGKINSiarn 435
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIRE---- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 436 nnisMFNAGSKMIQDSTSKVNIEINEFIR----------------------KVHKWYNLK--KEIDHIELTQLILEDSKY 491
Cdd:pfam13361 157 ----YKKRGLRLSDFINPDTLTYGDPFVIaleqdnivvfdvettgldttedEIIQIAAIKlnKKGVVIESFERFLRLKKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 492 VE--------YLEQEEKNSKNPEN-----LNRLENIKEFIESLKDFEN----------LEGFLEHVGLVMENISNTND-E 547
Cdd:pfam13361 233 VGdslqvhgfSDEFLQENGETPAEalrdfLEKLENLRELYSILREYDDieetpepedaLRNFLEIATLSNSELEGSDIkE 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1347645574 548 SISLMTMHSAKGLEFDNVFLAGWEEGVFPSMRSIDELGkkGLEEERRLAYVALTRARRKIHITYVNQ 614
Cdd:pfam13361 313 RIPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEG--NLEEERRLFYVAITRAKKRLYISYSKS 377
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
16-607 |
6.30e-33 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 136.76 E-value: 6.30e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 16 QRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSnQILAVTFTNKAASEMKIRVSNLLNYPIDK--------- 86
Cdd:TIGR02785 6 QWQAIYTRGQDILVSASAGSGKTAVLVERIIRKITRGVDVD-RLLVVTFTNAAAREMKERIAEALEKELVQepnskhlrr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 87 -------MWLGTFHSLSAKILRAHAELVGLKSNFIIID---------------------------------------SDD 120
Cdd:TIGR02785 85 qlallntANISTLHSFCLKVIRKHYYLLDLDPSFRILTdteqlllikevlddvfeeeyykedkeaffelvdnfsgdrSDD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 121 QLK-LIKQICEH------------------------------------------------------KNIDIKEKPPKYFA 145
Cdd:TIGR02785 165 GLRdLILQLYDFsrstpnpekwlnnlaeayevkekftieslklqqqikellkneleglqeklqralELFMAEDGLAPRLE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 146 TVIDNYKNKGIFPQ------------------SVKSSKGKKGEENIAIIYKL---------------------------- 179
Cdd:TIGR02785 245 NFQLDLQNIDELIQeslaqadwnelrkavaafKFKNLKAAKGDEEDADLLEEadklreeakkqleklktdyftrseedhl 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 180 -----------------------YQEELLRLNCVDFGDLILFCIKIFKEN----KEVCSKYQNLFKFILVDEYQDINNVQ 232
Cdd:TIGR02785 325 rimqemkpvvktlvqlvkdfierFGAEKREKNILDFSDLEHYALQILTNEnespSEAAEFYREKFHEVLVDEYQDTNLVQ 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 233 QQWLEFFYQGHK---NICCVGDDDQSIYSWRGADVNILLNFEKNFSKP-----LIIRLEQNYRSTKNILECASFLIAK-- 302
Cdd:TIGR02785 405 ESILQLVKRGPEeegNLFMVGDVKQSIYRFRQADPLLFLEKYHRFAQEgeehgKRIDLAENFRSRAEVLDTTNFLFKQlm 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 303 ------------------------NKGRYGKELWSDKDKGEKISIKGFWHTKE-------ESVYVSDEIEKLISNKTPL- 350
Cdd:TIGR02785 485 deevgeidydeeaqlkfgaakypeNPDNKTEELLYEKLLIEEAEEEEIDEEAEildkaqqEATMVAERIKALIKEGFKVy 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 351 ------------SEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAYLRLVHNLDDNLALERIINVPK 418
Cdd:TIGR02785 565 dkktgtyrpvtyRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDIPLVAVLRSPI 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 419 RGIGRTTLGKINsiARNNNISMFNAGSKMIQDST--SKVNIEINEFIRKVHKWYNLKKEIDHIELTQLILEDSKYVEYLe 496
Cdd:TIGR02785 645 VGFDENELALIR--LENKDSSYYEAVKDYVKAGLieDELYEKLNTFLDSLQKWREFARTHSVSELIWKIYNDTGYYDYV- 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 497 qeeknSKNPENLNRLENIKEFIESLKDFEN-----LEGFLEHVGLVME--------NISNTNDESISLMTMHSAKGLEFD 563
Cdd:TIGR02785 722 -----GGLPGGKQRQANLYALYERARQYEStsfkgLFQFIRFIERMQErqkdlasaVAVGEAENAVRLMTIHKSKGLEFP 796
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1347645574 564 NVFLAGW-----------------EEGV------------FPSMRSI---DELGKKGLEEERRLAYVALTRARRKI 607
Cdd:TIGR02785 797 VVFVLGMgkqfnkqdlnssylldrQLGLgikyidpqerlsYPSLPKVaikQKMKRELLSEEMRVLYVALTRAKEKL 872
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
16-358 |
1.71e-29 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 124.68 E-value: 1.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 16 QRKAVVNSKGSTLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVSNLLNypIDKMWLGTFHSL 95
Cdd:PRK11054 201 QARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERLG--TEDITARTFHAL 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 96 SAKILRAhaelVGLKSNFI-IIDSDDQLK---LIK---QICEHKNIDIK---EKPPKYFATVIDnyknKGIFPQ------ 159
Cdd:PRK11054 279 ALHIIQQ----GSKKVPVIsKLENDSKARhalLIAewrKQCSEKKAQAKgwrQWLTEELQWDVP----EGNFWDdeklqr 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 160 ----------SVKSSKGKKGEENIAII------------------YKLYQEELLRLNCVDFGDLILFCIKIFKENkevcs 211
Cdd:PRK11054 351 rlasrlerwvSLMRMHGGSQAEMIAQApeevrdlfqkrlklmaplLKAWKKALKAENAVDFSGLIHQAVNYLEKG----- 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 212 KYQNLFKFILVDEYQDINNVQQQWLEFF--YQGHKNICCVGDDDQSIYSWRGADVNILLNFEKNFSKPLIIRLEQNYRST 289
Cdd:PRK11054 426 RFISPWKHILVDEFQDISPQRAALLAALrkQNSQTTLFAVGDDWQAIYRFSGADLSLTTAFHERFGEGDRCHLDTTYRFN 505
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1347645574 290 KNILECASFLIAKNKGRYGKELWSDKDKGEKisikgfwhtkeeSVYV--SDEIEKLI----SNKTPLSEIAILFR 358
Cdd:PRK11054 506 SRIGEVANRFIQQNPHQLKKPLNSLTKGDKK------------AVTLlpEDQLEALLdklsGYAKPDERILLLAR 568
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
549-611 |
3.70e-23 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 96.15 E-value: 3.70e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1347645574 549 ISLMTMHSAKGLEFDNVFLAGWEEGVFPSMRS--IDELGKKGLEEERRLAYVALTRARRKIHITY 611
Cdd:cd18807 86 VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASyhAAKEDEERLEEERRLLYVALTRAKKELYLVG 150
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
25-604 |
5.75e-23 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 104.82 E-value: 5.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 25 GSTLVLAGAGSGKTRVLTFRILHLLIEKLAFS-NQILAVTFTNKAASEMKIRV--------SNLLNYP------------ 83
Cdd:TIGR00609 10 GTFLIEASAGTGKTFTIAQLYLRLLLEGGPLTvEEILVVTFTNAATEELKTRIrgrihqalRALKAALtsqelpeplkea 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 84 -------------------IDKMWLGTFHSLSAKILRAHAELVG-LKSNFIIIDSDDQLKLI------------------ 125
Cdd:TIGR00609 90 iqdekvkqaitrlrnalatMDEAAIYTIHGFCQRMLEQHAFESDeIFDVELIEDESLLLAEItkdfwrrnfynlpfdiaq 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 126 -------------KQICEHK----NIDIKEKPPKYFATVID---NYKNKGIFPQSVKSSKGKKGEEN-------IAIIYK 178
Cdd:TIGR00609 170 ivlktkkspqavlTQILADLllqsYLAFPSPPLDLEQLIKWheqIYKDLDKLDHAVFEEIDKLNAERnnlfclkDRVFLT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 179 LY---QEELL----RLNCVDFGDLILFCIKIFK--ENKEVCSKYQNLFKFILVDEYQDINNVQQQWLEFFYQGHKNICC- 248
Cdd:TIGR00609 250 LLkevQEELKkekkRRREIGFDDLLSRLETALKsaEGEKLAQAIREQYPIALIDEFQDTDPQQYRIFSKLFIAQKETSLf 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 249 -VGDDDQSIYSWRGADVNILLNFEKNFSKPLIirLEQNYRSTKNILECASFLIAKN------KGRYGKELWSDKDKGEKI 321
Cdd:TIGR00609 330 lIGDPKQAIYSFRGADIFTYLQAKSKADARYT--LGTNWRSTPALVGSLNKLFSLIsnpfleKPIFIPVLAHQKNSKGSF 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 322 SIKG-------FWHTKEESVYVsDEIEKLISNKTPLSEIAILFRVSAHTRSFEDRFINLGLSYKIIGGLrFYERKE---I 391
Cdd:TIGR00609 408 VINGqeqppihFFTTEVESEGV-DDYRQTIAQKCAREIALWLASAALGLANFIATFGGRPLRAGDIAVL-VRGRKEanqI 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 392 RDVIAYLRLVHNLDDN-------------LALERIINVPKRGigrttlGKINSIARNnniSMFNAGSKMIQDstskVNIE 458
Cdd:TIGR00609 486 RKALKKAQIPSVYLSDkssvfateeaqelLALLEALLEPENE------GTLRAALAS---SIFGLSALELET----LNQD 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 459 INEFIRKVHKWYNLKKEIDHI----ELTQLILEDSKYVEYLEQEEKNsknpENLNRLENIKEFIEslKDFENLEGFLEHV 534
Cdd:TIGR00609 553 EITWERVVEKFREYHDIWRKIgvlaMFQRLMLEKGIGERLLSQPGGE----RILTNLLHLAELLQ--EAAHQERNKLSLL 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 535 GLVMENISNTN------------DESISLMTMHSAKGLEFDNVFLAG---WEE-----------------GVFPSMRSID 582
Cdd:TIGR00609 627 RWLEDQISNEEeeeeeiirlesdAELVKIVTIHKSKGLEYPIVFLPFitdAKKsnfaslhdqhsheyqlyDFNQSEENQK 706
|
730 740
....*....|....*....|..
gi 1347645574 583 ELGKKGLEEERRLAYVALTRAR 604
Cdd:TIGR00609 707 LARVERLAEDLRLLYVALTRAK 728
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
28-693 |
2.21e-18 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 90.19 E-value: 2.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 28 LVLAGAGSGKTRvltfRILHLLIEKLAFSNQILAVTfTNKAASEMKIRVsnLLNYPIDKMWLG---TFHSLSAKILRaha 104
Cdd:COG3857 2 FILGRAGSGKTT----YLLEEIKEELKEGKPIILLV-PEQMTFQAERAL--LKRLGLGGSIRAqvlSFSRLAWRVLQ--- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 105 ELVGLKSNFiiIDSDDQLKLIKQIcehknIDIKEKPPKYFATVIDN-------------YKNKGIFPQSVKSSKGKKGE- 170
Cdd:COG3857 72 ETGGATRPL--LSDAGKRMLLRKI-----LEEHKDELKVFARAADKpgfieqlaeliteLKRYGITPEDLEEAAELLKEk 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 171 -ENIAIIYKLYQEELLRLNcVDFGDLILFCIKIFKENKEVcskyQNlfKFILVDEYQDINNVQQQWLEFFYQGHKNIC-- 247
Cdd:COG3857 145 lRDLALIYEAYEEKLAGRY-IDSEDLLRLLAEKLEKSEFL----EG--AEIYIDGFTDFTPQELELLEALLKKAKEVTit 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 248 -CVGDDDQSIYSWRGADVNILLNFEKN-------FSKPLIIRLEQNYRSTknilecasfliaknkgrygkelwSDKDKGE 319
Cdd:COG3857 218 lTLDPDELDLFSATGETYERLLELAKEngvevefKKSPELAHLERNLFAY-----------------------PPEEEPE 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 320 KISIKGFWHTKEESVYVSDEIEKLISNK-TPLSEIAILFR-VSAHTRSFEDRFINLGLSYKIIGGLRFYERKEIRDVIAY 397
Cdd:COG3857 275 GIEIIEAANRRAEVEAVAREIRRLVREEgYRYRDIAVVVRdLEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILSL 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 398 LRLVHNlddNLALERIINVPK----RGIGRTTLGKINSIARNNNI------SMFNAGSKMIQDSTSKVNIEINEFIRKVH 467
Cdd:COG3857 355 LELVRS---NFRYEDVFRLLKtgllRPLSREEIDRLENYVLAYGIrgrrwlERYLEEEEELTDEEEEDLERLNELRDRLL 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 468 KW-YNLKKEI-------DHIELTQLILEDSKYVEYLEQEEKNSKNPENLNRLEN---IKEFIESLKDFENLEG------- 529
Cdd:COG3857 432 EPlLPLRERLkkaktvrEWAEALYEFLEELGVPEKLEEWREAEEAGDLEEAREHeqaWNALIELLDELVEVLGdeklsle 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 530 -FLEHVGLVMEN-----ISNTNDEsISLMTMHSAKGLEFDNVFLAGWEEGVFPSMRSID---------ELGKKGLE---- 590
Cdd:COG3857 512 eFLRILESGLEEltfglIPPSLDQ-VQVGGLDRARGLDFKAVFVLGLNEGVFPARPREDgllsdeereRLNELGLElppt 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 591 ------EERRLAYVALTRARRKIHITYVNQNRysyvSHDFNMPSRFIEELPKNLVNINNSTYLSnnnfiDEFSQIENMDS 664
Cdd:COG3857 591 srerllEERFLFYRALTRASERLYLSYPLADE----EGKALLPSPLIDRLRELFPELEERSLLE-----EELEYIGTPES 661
|
730 740
....*....|....*....|....*....
gi 1347645574 665 SFitpgrKRLLSRIKKEEDDWDFNQDYQS 693
Cdd:COG3857 662 AL-----SELAAALRQLELAPLWWDVYKW 685
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
31-609 |
3.09e-15 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 80.01 E-value: 3.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 31 AGAGSGKTRVLTFRILHLLIeKLAFSNQILAVTFTNKAASEMKIRV------------SNLLN-----YPIDKMWL---- 89
Cdd:PRK13909 5 ASAGSGKTFALSVRFLALLF-KGANPSEILALTFTKKAANEMKERIidtllnlekekeESELNeleekLGLSKEELlnkr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 90 --------------GTFHSLSAKILRAHAELVGLKSNFIIIDSDdqlklIKQICEH--KNIDIKE-KPPKYFATVIDNYK 152
Cdd:PRK13909 84 dkvyqeflnselkiSTIDAFFQKILRKFCLNLGLSPDFSIKEDT-----KEELNEKflSALSKEElLELLAFIKQCESKK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 153 NKGIF-------PQSVKSSKGKKGEENIAIIYKLYQEELLRLN------------------CVDFGDL------------ 195
Cdd:PRK13909 159 NNSFFelleklyEKNNELKLFEKAKNPIEFDEEKFLEELRSLKqqiqsietasknakkafkKEDFEELlnssktwlekes 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 196 ---------------ILFCIK-----------------------IFKENKEVCSKYQNLFKF------------------ 219
Cdd:PRK13909 239 eyryfkklyneeldaEFEELKnalkryydakenyklsklfkllqLYKEAKNELNKKKNALDFddiskkvyellgeeeidk 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 220 -------------ILVDEYQDINNVQQQWLE-----------------FFYqghkniccVGDDDQSIYSWRGADVNIlln 269
Cdd:PRK13909 319 dflyfrldskishILIDEFQDTSVLQYKILLplideiksgegqkkfrsFFY--------VGDVKQSIYRFRGGKKEL--- 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 270 FEK--NFSKPLIIRLEQNYRSTKNILECASFLIAKNKGRYGKELWSDKDKGEKISIKGFWHTKEESV-YVSDEIEKLISN 346
Cdd:PRK13909 388 FDKvsKDFKQKVDNLDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSGGYVEVVEVADESEELLeQLLQEIQFLLEK 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 347 KTPLSEIAIlfrvsahtrsfedrfinlglsykiigglrfyerkeirdviaylrLVHNLDDNLALEriinvpkrgigrttl 426
Cdd:PRK13909 468 GIDPDDIAI--------------------------------------------LCWTNDDALEIK--------------- 488
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 427 gkiNSIARNNNISMFNAGS-KMIQDSTSKVNIEINEFI---RKVHKwYNLKKEIDHiELTQLILEDSkyveyleqeeKNS 502
Cdd:PRK13909 489 ---EFLQEQFGIKAVTESSaKLINQPEVKALIEALKYClfgEEIYK-HNVLKLLGK-EPDKIPSFLP----------KEE 553
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 503 KNPENLNRL--------ENIKEFIESLKDFENLEGFLEHVGLVMENISNTNDESISLMTMHSAKGLEFDNVFLA------ 568
Cdd:PRK13909 554 SVAEFVKKLieelklydENLLKFLELASGYEDIEEFLFKLEPCDKEIASEESKGVQIMTVHKSKGLEFEHVIVCdrlgkp 633
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1347645574 569 ---------------GWEegVFPSMR---SIDELGKKGLEEERRL--------AYVALTRARRKIHI 609
Cdd:PRK13909 634 nsdssnllfeydgieLWQ--IYYRIKgreNFDKDYARALEKEKALkyeeeinvLYVAFTRAKNSLIV 698
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
190-604 |
1.73e-13 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 74.34 E-value: 1.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 190 VDFGDLILFCIKIFKENKE---VCSKYQNLFKFILVDEYQDINNVQQQWL-----EFFY------QGHKNICCVGDDDQS 255
Cdd:TIGR02784 361 LDFNDLIERTVALLARPGAgawVHYKLDRGIDHILVDEAQDTSPEQWDIIqalaeEFFSgegarsGVERTIFAVGDEKQS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 256 IYSWRGADVNILL-----------NFEKNFSKpliIRLEQNYRSTKNILECASFLIAKNKGRYGK--------------- 309
Cdd:TIGR02784 441 IYSFQGADPERFAeerrefsrkvrAVGRKFED---LSLNYSFRSTPDVLAAVDLVFADPENARGLsadsdapvheafrdd 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 310 -----ELWS--DKDKGEKIS--IKGFWHTKEESVYV------SDEIEKLISNKTPL---------SEIAILFR-----VS 360
Cdd:TIGR02784 518 lpgrvDLWDliSKEEGEEPEdwTDPVDELGERAPEVrlaeriAAEIRAWLDRGTPIpgrgravrpGDILVLVRkrdafFS 597
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 361 AHTRSFEDRFInlglsyKIIGGLRFYERKEI--RDVIAYLRLVHNLDDNLALERIINVPKRGIGRTTLGKInsIARNNNI 438
Cdd:TIGR02784 598 ALIRALKRRGI------PVAGADRLKLTSHIavKDLMALGRFVLQPEDDLSLAALLKSPLFGLDEDDLFRL--AAGRSGG 669
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 439 SMFNAgskmIQDSTSkvniEINEFIRKVHKWYNLKKEIDHIELTQLIL----EDSKYVEYLEQEEKnsknpenlnrlENI 514
Cdd:TIGR02784 670 SLWAA----LRRREA----EFAATLAVLRDWLSLADFLTPFEFYARLLgrdgGRRKLLARLGAEAE-----------DIL 730
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 515 KEFIESLKDFE-----NLEGFLEHVGL----VMENISNTNDEsISLMTMHSAKGLEFDNVFL-----AGWEEGVFPSMRS 580
Cdd:TIGR02784 731 DEFLSQALAYErtglpGLQAFLSWLEAddpeIKREMDQARDE-VRVMTVHGAKGLEAPVVFLvdtgsKPFASQRAPLLLA 809
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1347645574 581 -------------------------IDELGKKGLEEERRLAYVALTRAR 604
Cdd:TIGR02784 810 tggsggkaplwrpasafdpslsaaaRERLKERAEDEYRRLLYVAMTRAE 858
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
16-134 |
3.24e-13 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 67.24 E-value: 3.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 16 QRKAVVNSKGST--LVLAGAGSGKTRVLTfRILHLLIEKLAFSNQILAVTFTNKAASEMKIRvsnlLNYPIDkmwlgTFH 93
Cdd:pfam13245 1 QREAVRTALPSKvvLLTGGPGTGKTTTIR-HIVALLVALGGVSFPILLAAPTGRAAKRLSER----TGLPAS-----TIH 70
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1347645574 94 SLSAKILRAHAELVGLKSNF-----IIID--SD-D---QLKLIKQICEHKNI 134
Cdd:pfam13245 71 RLLGFDDLEAGGFLRDEEEPldgdlLIVDefSMvDlplAYRLLKALPDGAQL 122
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
217-286 |
4.95e-11 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 60.58 E-value: 4.95e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1347645574 217 FKFILVDEYQDINNVQQQWLEFFYQGHKNICCVGDDDQSIYSWRGADVNILLNFEKNFSKPL-----IIRLEQNY 286
Cdd:cd17914 47 LDNILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAKICNEQSLFTRLVrlgvsLIRLQVQY 121
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
15-372 |
7.93e-10 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 62.16 E-value: 7.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 15 QQRKAVVN-SKGSTLVLAGAGSGKTRVLTFRILHLLIEklaFSNQILAVTFTNKA-ASEMKIRVSNLLNY-----PIDKM 87
Cdd:COG3972 163 QQERIARSiPDGPQRIRGVAGSGKTVLLAAKAAYLALK---HPGWRILVTCFNRSlADHLRDLIPRFLRRfsngePEDNV 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 88 WLGTFHSLSAKILRAHaelvGLKSNFIIIDSDDQLKLIKQICEhkNIDIKEKPPKYFAtvidnyknkgifpqsvksskgk 167
Cdd:COG3972 240 KLIVFHAWGGKLLKQY----GIPPLTFSQPNEAFDEACKALLE--AIQGEIIPPIYDA---------------------- 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 168 kgeeniaiiyklyqeellrlncvdfgdlilfcikifkenkevcskyqnlfkfILVDEYQDInnvQQQWLEFFYQ----GH 243
Cdd:COG3972 292 ----------------------------------------------------ILIDEAQDF---EPEFLRLLYQllkpPK 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 244 KNICCVGDDDQSIYSWR-GADVNILLNFEKnfskplIIRLEQNYRSTKNILECA----------SFLIAKNKGRYGKELW 312
Cdd:COG3972 317 KRLIWAYDEAQNIYGRKiPSAGGIPAGIGR------DTILKKNYRNTRPILTFAhafgmgllrpPGLLQGDAEDYEVERP 390
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1347645574 313 SDK-----------DKGEKISIKGFWHTKEESVYVSDEIEKLISNKT-PLSEIAILFRVSAHTRSFEDRFIN 372
Cdd:COG3972 391 GDKvtlirppepagRKGPLPEFKKYDDRAEELEAIAEEIKKNLRDEGlRPSDIAVIYLGNNEAKELGDRLAA 462
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
26-122 |
8.01e-10 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 57.11 E-value: 8.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 26 STLVLAGAGSGKTRVLTFRILHLLIEKLAFSNQILAVTFTNKAASEMKIRVsnllnypIDKmwlgtfhslSAKILRAH-- 103
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLDNIL-------VDE---------AAQILEPEts 64
|
90 100
....*....|....*....|.
gi 1347645574 104 --AELVGLKSNFIIIDSDDQL 122
Cdd:cd17914 65 rlIDLALDQGRVILVGDHDQL 85
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
513-613 |
2.03e-09 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 60.62 E-value: 2.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 513 NIKEFIESLKDFENLEGFLEHVGLVMENISN-TNDESISLMTMHSAKGLEFDNVFLAGweegvfpsmrsIDELGK-KGLE 590
Cdd:COG3972 452 EAKELGDRLAAALERQGIDSYIAGARSDPNFfWKDGGVTISTIHRAKGLEAPVVIIVG-----------LDQLAKgESLE 520
|
90 100
....*....|....*....|...
gi 1347645574 591 EERRLAYVALTRARRKIHITYVN 613
Cdd:COG3972 521 RLRNLLYVAMTRARGWLVVSGSG 543
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
551-610 |
4.09e-08 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 51.28 E-value: 4.09e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 551 LMTMHSAKGLEFDNVFLAGWEEGvfpsmrsidelgkkglEEERRLAYVALTRARRKIHIT 610
Cdd:cd18786 45 AITIDSSQGLTFDVVTLYLPTAN----------------SLTPRRLYVALTRARKRLVIY 88
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
552-610 |
9.83e-08 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 49.11 E-value: 9.83e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1347645574 552 MTMHSAKGLEFDNVFLAGweegvfpsmrsIDELGKKGLEEERRLAYVALTRARRKIHIT 610
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVD-----------PDLTAHYHSMLRRRLLYTAVTRARKKLVLV 52
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| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
552-609 |
1.57e-07 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 49.10 E-value: 1.57e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1347645574 552 MTMHSAKGLEFDNVFLAgweegvfpsmrsideLGKKGLEEERRLAYVALTRARRKIHI 609
Cdd:cd18809 36 MTIHKSQGSEFDRVIVV---------------LPTSHPMLSRGLLYTALTRARKLLTL 78
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|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
546-613 |
2.33e-06 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 51.02 E-value: 2.33e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347645574 546 DESISLMTMHSAKGLEFDNVFLagweegVFPSMRSIDElgkkglEEERRLAYVALTRARRKIHITYVN 613
Cdd:COG3973 636 EAGVVVLPAYLAKGLEFDAVVV------VDPDEIVYES------PRGRRLLYVALTRATHRLTVLHTG 691
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
552-609 |
3.58e-05 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 46.89 E-value: 3.58e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1347645574 552 MTMHSAKGLEFDNVFLagweegVFPSMRSIdelgkkglEEERRLAYVALTRARRKIHI 609
Cdd:COG0507 445 ITVHKSQGSTFDRVIL------VLPSEHSP--------LLSRELLYTALTRARELLTL 488
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
28-99 |
6.73e-04 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 39.04 E-value: 6.73e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1347645574 28 LVLAGAGSGKTRVLTFRILHLliekLAFSNQILAVTFTNKAASEMKIRV--SNLLNYPIDKMWLGTFHSLSAKI 99
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIASA----MSSGKSVLVVTPTKLLAHEILIVIdeIQ*ILDPAAGWAWATRALLGLKA 72
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
217-296 |
1.21e-03 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 42.16 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347645574 217 FKFILVDEYQDINNVQqqW---LEFFYQGHKNIccVGDDDQSIYSWRGA-DVNILLN--FEKNFSkplIIRLEQNYRSTK 290
Cdd:COG3973 470 YGHVVVDEAQDLSPMQ--WrvlKRRFPSASFTI--VGDLAQAIHPYRGAeSWEEVLEplGGDRAR---LVELTKSYRSTA 542
|
....*.
gi 1347645574 291 NILECA 296
Cdd:COG3973 543 EIMEFA 548
|
|
| Viral_helicase1 |
pfam01443 |
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated ... |
542-609 |
1.41e-03 |
|
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated and NTPase activity. This helicase has multiple roles at different stages of viral RNA replication, as dissected by mutational analysis.
Pssm-ID: 366646 [Multi-domain] Cd Length: 227 Bit Score: 40.83 E-value: 1.41e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347645574 542 SNTNDESISLMTMHSAKGLEFDNVFLagweegvFPSMRSIDELgkkgLEEERRLAYVALTRARRKIHI 609
Cdd:pfam01443 169 ALKESLGVRVTTVHEVQGLTFDSVTL-------VLDTDTDLLI----ISDSPEHLYVALTRHRKSLHI 225
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
15-73 |
9.00e-03 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 39.19 E-value: 9.00e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1347645574 15 QQRKAV---VNSKGSTLVLAGAGSGKTRVLTfRILHLLiEKLAFsnQILAVTFTNKAASEMK 73
Cdd:COG0507 128 EQREAValaLTTRRVSVLTGGAGTGKTTTLR-ALLAAL-EALGL--RVALAAPTGKAAKRLS 185
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