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Conserved domains on  [gi|1317522668|gb|PKZ16357|]
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carbohydrate ABC transporter permease [Alloscardovia omnicolens]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-277 3.20e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 294.31  E-value: 3.20e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   2 KNPKTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLFPTPSTLDNYVSIQENFNFLRLFGNSVFVA 81
Cdd:COG0395     4 TARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  82 TVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLV--SGFGIFLF 159
Cdd:COG0395    84 VVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 160 RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAFNGQYG 239
Cdd:COG0395   164 RQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG 243

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1317522668 240 TDYGGLFAATSLAIVPVIIVYMVFQKQFIAGIATGSSK 277
Cdd:COG0395   244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-277 3.20e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 294.31  E-value: 3.20e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   2 KNPKTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLFPTPSTLDNYVSIQENFNFLRLFGNSVFVA 81
Cdd:COG0395     4 TARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  82 TVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLV--SGFGIFLF 159
Cdd:COG0395    84 VVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 160 RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAFNGQYG 239
Cdd:COG0395   164 RQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG 243

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1317522668 240 TDYGGLFAATSLAIVPVIIVYMVFQKQFIAGIATGSSK 277
Cdd:COG0395   244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
17-271 1.14e-36

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 131.40  E-value: 1.14e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  17 VLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLFPTPSTLDNYVSIQEN------FNFLRLFGNSVFVATVKTVIIIY 90
Cdd:PRK10973   14 TMLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVNgvgnnsAPFGRMLLNSFVMAFSITVGKIT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  91 TSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLVSGFGIFLFRQSISGISDEL 170
Cdd:PRK10973   94 VSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDEL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 171 IEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAF--NGQYGTDYGGLFAA 248
Cdd:PRK10973  174 VEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMiaTGEGTTEWNQVMAA 253

                         250       260
                  ....*....|....*....|...
gi 1317522668 249 TSLAIVPVIIVYMVFQKQFIAGI 271
Cdd:PRK10973  254 MLLTLIPPVVIVLAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-257 5.41e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.07  E-value: 5.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  74 FGNSVFVATVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLV-- 151
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIla 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 152 ----SGFGIFLFRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLL 227
Cdd:cd06261    81 llliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1317522668 228 AVGLKAFNGQYGTDYGGLFAATSLAIVPVI 257
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 94-271 6.51e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 6.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  94 LLGFVFAKMR-FFGRDFLFAIVMSTMMIPWAVTIIP--QYEMMVSFGWLDSYKALIIPGLVSGFGIFLFRQSISGISDEL 170
Cdd:pfam00528   3 PLGIIAALRRgRRLDRLLRPLIDLLQALPSFVLAILlvVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 171 IEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDEskqllAVGLKAFNGQYGTDYG---GLFA 247
Cdd:pfam00528  83 VEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPeiqGPVL 157

                         170       180
                  ....*....|....*....|....
gi 1317522668 248 ATSLAIVPVIIVYMVFQKQFIAGI 271
Cdd:pfam00528 158 AAALILLLLNLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 10-205 3.06e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 38.89  E-value: 3.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  10 IGSVILTVLLFVVAlitivPFLWMFISSFAPNSeivkingGLFptpSTLDNYVSIQENFNFLRLFGNSVFVATVKTVIII 89
Cdd:TIGR03262   7 LAGMILALLLFLLL-----PLLALLTKSVYDSD-------GDF---IGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  90 YTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPwavTIIPQYEMMVSFG-------WLDSYKALIIPGLVSGFGIFLFRQ- 161
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAP---SLLPAISLIYLFGnqgllkgLLGGFSIYGFWGIVIGEVFYTFPHa 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1317522668 162 ------SISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTF 205
Cdd:TIGR03262 149 lmilvtALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVF 198
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-277 3.20e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 294.31  E-value: 3.20e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   2 KNPKTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLFPTPSTLDNYVSIQENFNFLRLFGNSVFVA 81
Cdd:COG0395     4 TARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  82 TVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLV--SGFGIFLF 159
Cdd:COG0395    84 VVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 160 RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAFNGQYG 239
Cdd:COG0395   164 RQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYG 243

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1317522668 240 TDYGGLFAATSLAIVPVIIVYMVFQKQFIAGIATGSSK 277
Cdd:COG0395   244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 1-277 3.86e-54

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 176.88  E-value: 3.86e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   1 MKNPKTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNSEIvkINGGLFPTPSTLDNYVSIQENFNFLRLFGNSVFV 80
Cdd:COG3833     4 RKSRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSL--YSSSLIPENFTLENYKKLFTETPFLRWFLNSLIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  81 ATVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIP--GLVSGFGIFL 158
Cdd:COG3833    82 AVVTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVylGGAIPFNTWL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 159 FRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAF-NGQ 237
Cdd:COG3833   162 MKGYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFvSDQ 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1317522668 238 YGTDYgGLFAATS-LAIVPVIIVYMVFQKQFIAGIATGSSK 277
Cdd:COG3833   242 RNTNW-GVFAAGAvLVAIPIVILFLFLQRYLVSGLTAGGVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
17-271 1.14e-36

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 131.40  E-value: 1.14e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  17 VLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLFPTPSTLDNYVSIQEN------FNFLRLFGNSVFVATVKTVIIIY 90
Cdd:PRK10973   14 TMLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVNgvgnnsAPFGRMLLNSFVMAFSITVGKIT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  91 TSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLVSGFGIFLFRQSISGISDEL 170
Cdd:PRK10973   94 VSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDEL 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 171 IEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLLAVGLKAF--NGQYGTDYGGLFAA 248
Cdd:PRK10973  174 VEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMiaTGEGTTEWNQVMAA 253

                         250       260
                  ....*....|....*....|...
gi 1317522668 249 TSLAIVPVIIVYMVFQKQFIAGI 271
Cdd:PRK10973  254 MLLTLIPPVVIVLAMQRAFVRGL 276
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 10-212 1.77e-15

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 73.99  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  10 IGSVILTVLLFVVALITIVPFLWMFISSFAPNSeivkiNGGLFPTPSTLDNYVSIQENFNFLRLFGNSVFVATVKTVIII 89
Cdd:COG1177     4 LGRLLLRLFLALVLLFLYLPILVLVLYSFNDSW-----FLTFPPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLAT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  90 YTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLVSG--FGIFLFRQSISGIS 167
Cdd:COG1177    79 VLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTlpFVVLVVLARLQGFD 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1317522668 168 DELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDY 212
Cdd:COG1177   159 PSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEF 203
malG PRK10998
maltose ABC transporter permease MalG;
1-277 6.66e-15

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 73.20  E-value: 6.66e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   1 MKNPKTARTIGSVILTVLLFVVALItIVPFLWMFISSFAPNSEIVkinGGLFPTPSTLDNY-----VSIQEN-------- 67
Cdd:PRK10998    3 MVQPKSQKLRLFATHLLLLGFIALI-MFPLLMVIAISLREGNFAT---GSLIPEQISWEHWklalgFSVEHAdgrvtppp 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  68 FNFLRLFGNSVFVATVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMM------VSFGWLDS 141
Cdd:PRK10998   79 FPVLLWLWNSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFdrlgqyIPFIGLNT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 142 YKALIIPGLvsgFGIFLFRQSISG----ISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFL 217
Cdd:PRK10998  159 HGGVIFAYL---GGIALHVWTIKGyfetIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASL 235

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 218 MITDESKQLLAVGLKAFNGQYGTDYGGLFAATSLAIVPVIIVYMVFQKQFIAGIATGSSK 277
Cdd:PRK10998  236 LLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-218 1.46e-14

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 71.72  E-value: 1.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   1 MKNPKTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNSEIVKINGGLfptpsTLDNYVSIQENFNFLRLFGNSVFV 80
Cdd:COG1176     1 MSAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF-----TLENYARLFTDPLYLKVLLRTLWI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  81 ATVKTVIiiytSALLGFVFA----KMRFFGRDFLFAIVMSTMMIP-----WAVTIIPQYE-----MMVSFGWLD------ 140
Cdd:COG1176    76 ALLTTLI----CLLLGYPIAyflaRAPPRWRNLLLLLVILPFWTSflvrtYAWIVLLGRNgllnsLLLALGLIDeplrll 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 141 -SYKALIIpGLVSG---FGIFLFRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPF 216
Cdd:COG1176   152 yTEFAVVI-GLVYVylpFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPA 230


                  ..
gi 1317522668 217 LM 218
Cdd:COG1176   231 LL 232
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
19-218 1.78e-12

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 65.93  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  19 LFVVALITIVPFLWMFISSFApnseivkiNGGLFPTPST---LDNYVSIQENFNFLRLFGNSVFVATVKTVIIIytsaLL 95
Cdd:COG1175    28 LLLLLVFVLYPLLYTLYLSFT--------DWNLLGPPPEfvgLDNYARLFTDPRFWNALGNTLLFTVVSVPLQL----VL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  96 GFVFAKM---RFFGRDFLFAIVMSTMMIPWAVTII-------PQY----EMMVSFG-----WLDSYK----ALIIPGL-- 150
Cdd:COG1175    96 GLLLALLlnrKLRGRGFFRTLFFLPWVISPVVVALiwkwlfnPDYgllnALLGALGlepinWLGDPSlalpAVIIVTVwk 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1317522668 151 VSGFGIFLFRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLM 218
Cdd:COG1175   176 GTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVL 243
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-257 5.41e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.07  E-value: 5.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  74 FGNSVFVATVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIPQYEMMVSFGWLDSYKALIIPGLV-- 151
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIla 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 152 ----SGFGIFLFRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDESKQLL 227
Cdd:cd06261    81 llliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1317522668 228 AVGLKAFNGQYGTDYGGLFAATSLAIVPVI 257
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-206 3.75e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 62.87  E-value: 3.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668   5 KTARTIGSVILTVLLFVVALITIVPFLWMFISSFAPNseivkingglfptpstLDNYVSIQENFNFLRLFGNSVFVATVK 84
Cdd:COG1178     3 TRPRRRPRLLLLLLALLLALLVLLPLLALLLRAFTDG----------------LANFWALLSDPYLWRALGNTLLLALLV 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  85 TVIiiytSALLGFVFAKM----RFFGRDFLFAIVMSTMMIPwavTIIPQYEMMVSFG-------WLDSYKALIIP----- 148
Cdd:COG1178    67 TLL----SLLLGVPLAWLlartDFPGRRLLRWLLLLPLALP---PYVVALAWIALFGpngllntLLRALFGLEPPdiygl 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1317522668 149 -GLVSGFGIFLF-------RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFL 206
Cdd:COG1178   140 gGIILVLVLFNYpyvylllRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFL 205
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
13-206 1.25e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 58.25  E-value: 1.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  13 VILTVLLFVVALITIVPFLWMFISSFAPnseivkinggLFPTPSTLDNYVSIQENFNFLRLFGNSVFVATVKTVIIIYTS 92
Cdd:COG1178   289 LALALCLLLVLLGLLLPLLALLLWSLTK----------ALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLA 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  93 ALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVtiipqyemmVSFGWLDSYKALIIPGLVSGFGIFLF------------- 159
Cdd:COG1178   359 LLLAYLVRRRRGRLARLLDRLAMLPYAVPGIV---------LGLGLLLLFNRPLPLLLYGTLAILVLayvvrflpfalrs 429

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1317522668 160 -RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFL 206
Cdd:COG1178   430 lEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFV 477
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 94-271 6.51e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 6.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  94 LLGFVFAKMR-FFGRDFLFAIVMSTMMIPWAVTIIP--QYEMMVSFGWLDSYKALIIPGLVSGFGIFLFRQSISGISDEL 170
Cdd:pfam00528   3 PLGIIAALRRgRRLDRLLRPLIDLLQALPSFVLAILlvVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668 171 IEAARLDGASDTRIFHSLILPLSHNTIAALAIFTFLWNWEDYLWPFLMITDEskqllAVGLKAFNGQYGTDYG---GLFA 247
Cdd:pfam00528  83 VEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP-----GLGLLLIEAILGYDYPeiqGPVL 157

                         170       180
                  ....*....|....*....|....
gi 1317522668 248 ATSLAIVPVIIVYMVFQKQFIAGI 271
Cdd:pfam00528 158 AAALILLLLNLLVDILQRLLDPRV 181
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 10-199 9.76e-05

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 42.66  E-value: 9.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  10 IGSVILTVLLFVVALITIVPFLWMFISSFapNSEIVKINGGLFptpsTLDNYVSIQENFNFLRLFGNSVFVATVKTVIII 89
Cdd:PRK09500    1 MGRLLRGGFMTLVYAYLYIPIIILIVNSF--NSSRFGINWKGF----TTKWYELLFNNDSLLQAAQHSLTMAVFSATFAT 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  90 YTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVtiipqyeMMVSFGWLdsykaLIIPGLVSGFGIFLFRQ-------- 161
Cdd:PRK09500   75 LIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIV-------MAISLLVL-----FMLLGIQLGFWSLLFAHitfclpfv 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1317522668 162 ------SISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAA 199
Cdd:PRK09500  143 vvtvysRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAA 186
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 12-205 9.03e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 39.73  E-value: 9.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  12 SVILTVLLFVVALITIVPFLWMFISSFAPnseivkingglfpTPSTLDNYVSIQENFNFLRLfgnSVFVATVKTVIIIYT 91
Cdd:COG0555    10 GLTLGLTLLYLSLIVLLPLAALVLKAAGL-------------GWAEFWAVLTSPRVLAALKL---SLGTALIAALINLVF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  92 SALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTIIpqyeMMVSF----GWLDSY-KALIIPGLVSGFGIFL-------- 158
Cdd:COG0555    74 GLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGI----ALLLLfgpnGWLGQLlAPLGIKVAFTPLGIVLaqtfvslp 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1317522668 159 -----FRQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTF 205
Cdd:COG0555   150 fvvrtVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF 201
modB PRK09421
molybdate ABC transporter permease subunit;
77-205 1.36e-03

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 39.13  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  77 SVFVATVKTVIIIYTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPWAVTiipQYEMMVSFG-------WLDSYKALIIP- 148
Cdd:PRK09421   14 SLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVT---GYLLLISMGrrgfigqWLYEWFGISFAf 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1317522668 149 ---GLVSGFGIFLF-------RQSISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTF 205
Cdd:PRK09421   91 swrGAALAAAVMAFplmvraiRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 10-205 3.06e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 38.89  E-value: 3.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  10 IGSVILTVLLFVVAlitivPFLWMFISSFAPNSeivkingGLFptpSTLDNYVSIQENFNFLRLFGNSVFVATVKTVIII 89
Cdd:TIGR03262   7 LAGMILALLLFLLL-----PLLALLTKSVYDSD-------GDF---IGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1317522668  90 YTSALLGFVFAKMRFFGRDFLFAIVMSTMMIPwavTIIPQYEMMVSFG-------WLDSYKALIIPGLVSGFGIFLFRQ- 161
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAP---SLLPAISLIYLFGnqgllkgLLGGFSIYGFWGIVIGEVFYTFPHa 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1317522668 162 ------SISGISDELIEAARLDGASDTRIFHSLILPLSHNTIAALAIFTF 205
Cdd:TIGR03262 149 lmilvtALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVF 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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