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Conserved domains on  [gi|1175232|sp|P43988|]
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RecName: Full=Uncharacterized protein HI_0366; Flags: Precursor

Protein Classification

type IV pilus biogenesis/stability protein PilF/PilW( domain architecture ID 11494436)

type IV pilus biogenesis/stability protein PilF/PilW is an outer membrane lipoprotein that is required for multimerization and localization of type IV pilus secretin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 9-179 8.92e-72

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


:

Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 216.43  E-value: 8.92e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232      9 SAVIFPFIFSACVS-----QSASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQ 83
Cdd:TIGR02521   1 LALVFLLALTGCVTtpdvpRSSRTTDRNKAAKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     84 IENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQTLEK 163
Cdd:TIGR02521  81 LEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIEDPLYPQPARSLENAGLCALKAGDFDKAEKYLTR 160

                         170
                  ....*....|....*.
gi 1175232    164 LRQIDGKRAEKFNSLK 179
Cdd:TIGR02521 161 ALQIDPQRPESLLELA 176
 
Name Accession Description Interval E-value
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 9-179 8.92e-72

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 216.43  E-value: 8.92e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232      9 SAVIFPFIFSACVS-----QSASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQ 83
Cdd:TIGR02521   1 LALVFLLALTGCVTtpdvpRSSRTTDRNKAAKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     84 IENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQTLEK 163
Cdd:TIGR02521  81 LEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIEDPLYPQPARSLENAGLCALKAGDFDKAEKYLTR 160

                         170
                  ....*....|....*.
gi 1175232    164 LRQIDGKRAEKFNSLK 179
Cdd:TIGR02521 161 ALQIDPQRPESLLELA 176
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 34-167 1.42e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.41  E-value: 1.42e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG3914 112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 1175232  114 SQKKFEQAQQQFELALN-SPNyyhQADTFENIVLCAYSAQKMDIYQQTLEKLRQI 167
Cdd:COG3914 192 DLGRLEEAIAAYRRALElDPD---NADAHSNLLFALRQACDWEVYDRFEELLAAL 243
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 38-98 7.63e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.76  E-value: 7.63e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1175232   38 VELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLN 98
Cdd:cd24142   4 LEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELD 64
 
Name Accession Description Interval E-value
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 9-179 8.92e-72

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 216.43  E-value: 8.92e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232      9 SAVIFPFIFSACVS-----QSASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQ 83
Cdd:TIGR02521   1 LALVFLLALTGCVTtpdvpRSSRTTDRNKAAKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     84 IENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQTLEK 163
Cdd:TIGR02521  81 LEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIEDPLYPQPARSLENAGLCALKAGDFDKAEKYLTR 160

                         170
                  ....*....|....*.
gi 1175232    164 LRQIDGKRAEKFNSLK 179
Cdd:TIGR02521 161 ALQIDPQRPESLLELA 176
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 34-167 1.42e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.41  E-value: 1.42e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG3914 112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 1175232  114 SQKKFEQAQQQFELALN-SPNyyhQADTFENIVLCAYSAQKMDIYQQTLEKLRQI 167
Cdd:COG3914 192 DLGRLEEAIAAYRRALElDPD---NADAHSNLLFALRQACDWEVYDRFEELLAAL 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 28-134 4.64e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 4.64e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   28 LNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNN 107
Cdd:COG3914  72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLN 151

                        90       100
                ....*....|....*....|....*...
gi 1175232  108 FGTFLCSQKKFEQAQQQFELALN-SPNY 134
Cdd:COG3914 152 LGEALRRLGRLEEAIAALRRALElDPDN 179
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-168 1.09e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 1.09e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   33 AAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFL 112
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 1175232  113 CSQKKFEQAQQQFELALN-SPNYyhqADTFENIVLCAYSAQKMDIYQQTLEKLRQID 168
Cdd:COG4783  83 LKAGDYDEALALLEKALKlDPEH---PEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
34-178 6.47e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.17  E-value: 6.47e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG0457   8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1175232  114 SQKKFEQAQQQFELALN-SPNYyhqADTFENIVLCAYSAQKMDIYQQTLEKLRQIDGKRAEKFNSL 178
Cdd:COG0457  88 ALGRYEEALEDYDKALElDPDD---AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 34-130 2.51e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 2.51e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG4235  17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                        90
                ....*....|....*..
gi 1175232  114 SQKKFEQAQQQFELALN 130
Cdd:COG4235  97 QQGDYAEAIAAWQKLLA 113
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
34-172 2.65e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.63  E-value: 2.65e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG0457  42 AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232  114 SQKKFEQAQQQFELALN-SPNYyhqADTFENIVLCAYSAQKMDIYQQTLEKLRQIDGKRA 172
Cdd:COG0457 122 ELGRYDEAIEAYERALElDPDD---ADALYNLGIALEKLGRYEEALELLEKLEAAALAAL 178
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
34-178 5.07e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 5.07e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG0457  76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1175232  114 SQKKFEQAQQQFELALNSPNYYHQADTFENIVLCAYSAQKMDIYQQTLEKLRQIDGKRAEKFNSL 178
Cdd:COG0457 156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALA 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-173 5.14e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 5.14e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   33 AAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFL 112
Cdd:COG2956   7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232  113 CSQKKFEQAQQQFELALNSPNYYHQAdtfenivlcaySAQKMDIYQQT---------LEKLRQIDGKRAE 173
Cdd:COG2956  87 LKAGLLDRAEELLEKLLELDPDDAEA-----------LRLLAEIYEQEgdwekaievLERLLKLGPENAH 145
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 34-129 6.74e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 6.74e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG2956 144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                        90
                ....*....|....*.
gi 1175232  114 SQKKFEQAQQQFELAL 129
Cdd:COG2956 224 KLGDPEEALELLRKAL 239
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
44-129 7.15e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.55  E-value: 7.15e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   44 YLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAfREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQ 123
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                ....*.
gi 1175232  124 QFELAL 129
Cdd:COG3063  81 YLERAL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 33-131 1.11e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.88  E-value: 1.11e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   33 AAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFL 112
Cdd:COG5010  53 AFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132

                        90
                ....*....|....*....
gi 1175232  113 CSQKKFEQAQQQFELALNS 131
Cdd:COG5010 133 LSLGQDDEAKAALQRALGT 151
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 34-130 5.18e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 5.18e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLC 113
Cdd:COG2956  76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                        90
                ....*....|....*..
gi 1175232  114 SQKKFEQAQQQFELALN 130
Cdd:COG2956 156 EQGDYDEAIEALEKALK 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 30-130 8.55e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.50  E-value: 8.55e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   30 HQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHkQGDVHNNFG 109
Cdd:COG2956 174 DPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP-SDDLLLALA 252

                        90       100
                ....*....|....*....|.
gi 1175232  110 TFLCSQKKFEQAQQQFELALN 130
Cdd:COG2956 253 DLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-168 1.71e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.73  E-value: 1.71e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   33 AAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFL 112
Cdd:COG2956 109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 1175232  113 CSQKKFEQAQQQFELALN-SPNYyhqADTFENIVLCAYSAQKMDIYQQTLEKLRQID 168
Cdd:COG2956 189 LEQGDYEEAIAALERALEqDPDY---LPALPRLAELYEKLGDPEEALELLRKALELD 242
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 25-178 2.92e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.22  E-value: 2.92e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   25 ASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDV 104
Cdd:COG3914  35 AALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA 114

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1175232  105 HNNFGTFLCSQKKFEQAQQQFELALN-SPNYyhqADTFENIVLCAYSAQKMDIYQQTLEKLRQIDGKRAEKFNSL 178
Cdd:COG3914 115 LFNLGNLLLALGRLEEALAALRRALAlNPDF---AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNL 186
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
22-176 3.65e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.65e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   22 SQSASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQ 101
Cdd:COG4785  61 ERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDY 140

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1175232  102 GDVHNNFGTFLCSQKKFEQAQQQFELALNspnyYHQADTFENIVLcaYSAQKMDIYQQTLEKLRQIDGKRAEKFN 176
Cdd:COG4785 141 AYAYLNRGIALYYLGRYELAIADLEKALE----LDPNDPERALWL--YLAERKLDPEKALALLLEDWATAYLLQG 209
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
77-168 7.29e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.55  E-value: 7.29e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   77 YYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAqQQFELALN-SPNYyhqADTFENIVLCAYSAQKMD 155
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKlDPNN---AEALLNLAELLLELGDYD 76

                        90
                ....*....|...
gi 1175232  156 IYQQTLEKLRQID 168
Cdd:COG3063  77 EALAYLERALELD 89
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 34-170 2.13e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 2.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     34 AKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFReyeIAVNLNHKQGD---VHNNFGT 110
Cdd:TIGR02917 397 AAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALA---AAKKLEKKQPDnasLHNLLGA 473

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1175232    111 FLCSQKKFEQAQQQFELALNS-PNYYHQADTFENIvlcAYSAQKMDIYQQTLEKLRQIDGK 170
Cdd:TIGR02917 474 IYLGKGDLAKAREAFEKALSIePDFFPAAANLARI---DIQEGNPDDAIQRFEKVLTIDPK 531
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 15-126 1.05e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     15 FIFSACVSQSASSLnhqtaakarVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIA 94
Cdd:TIGR02917  12 LALSACGDQSPEEL---------IEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKA 82

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1175232     95 VNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFE 126
Cdd:TIGR02917  83 LSLGYPKNQVLPLLARAYLLQGKFQQVLDELP 114
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 57-129 4.74e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.14  E-value: 4.74e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1175232   57 LDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELAL 129
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 36-101 8.57e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 8.57e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1175232   36 ARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQ 101
Cdd:COG4783  74 ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 25-167 2.68e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     25 ASSLNHQTAAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDV 104
Cdd:TIGR02917 116 KTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDA 195

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1175232    105 HNNFGTFLCSQKKFEQAQQQFELAL----NSPNYYHqadtfeNIVLCAYSAQKMDIYQQTLEKLRQI 167
Cdd:TIGR02917 196 LLLKGDLLLSLGNIELALAAYRKAIalrpNNIAVLL------ALATILIEAGEFEEAEKHADALLKK 256
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
61-129 5.06e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 5.06e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1175232   61 LQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQAQQQFELAL 129
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQAL 69
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
34-98 5.34e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 5.34e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1175232   34 AKARVELALSYLQQNNPQLAkINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLN 98
Cdd:COG3063  26 ADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 33-129 7.13e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 7.13e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232   33 AAKARVELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFL 112
Cdd:COG5010  19 KLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLY 98

                        90
                ....*....|....*..
gi 1175232  113 CSQKKFEQAQQQFELAL 129
Cdd:COG5010  99 SRSGDKDEAKEYYEKAL 115
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 38-98 7.63e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.76  E-value: 7.63e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1175232   38 VELALSYLQQNNPQLAKINLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLN 98
Cdd:cd24142   4 LEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELD 64
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 42-129 3.68e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 37.27  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1175232     42 LSYLQQNNPQLAKiNLDKALQHDKNYYLVHSALAHYYQQQGQIENAFREYEIAVNLNHKQGDVHNNFGTFLCSQKKFEQA 121
Cdd:TIGR00990 408 LHFIKGEFAQAGK-DYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEA 486


                  ....*...
gi 1175232    122 QQQFELAL 129
Cdd:TIGR00990 487 IEKFDTAI 494
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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