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Conserved domains on  [gi|121869|sp|P13044|]
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RecName: Full=Transcriptional activator GvpE1

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
83-148 5.63e-08

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 48.78  E-value: 5.63e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 121869    83 HIDEILLLLITVRDgACGKELLQDLRRLFGA--DLSPGTVYPHLNDLAVEGVLEVQKLS-----KRKVYRLSD 148
Cdd:COG1695   9 TLELLILALLAEGP-MYGYEIIKELEERSGGfwKVSEGTLYPALKRLEKEGLVESEWEEseggpRRKYYRLTE 80
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
83-148 5.63e-08

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 48.78  E-value: 5.63e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 121869    83 HIDEILLLLITVRDgACGKELLQDLRRLFGA--DLSPGTVYPHLNDLAVEGVLEVQKLS-----KRKVYRLSD 148
Cdd:COG1695   9 TLELLILALLAEGP-MYGYEIIKELEERSGGfwKVSEGTLYPALKRLEKEGLVESEWEEseggpRRKYYRLTE 80
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 86-161 5.52e-06

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 42.67  E-value: 5.52e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 121869    86 EILLLLitVRDGACGKELLQDLrrlfgaDLSPGTVYPHLNDLAVEGVLEVQKLSKRKVYRLSDPEGAFTRIDHMVD 161
Cdd:cd00090  11 RILRLL--LEGPLTVSELAERL------GLSQSTVSRHLKKLEEAGLVESRREGRRVYYSLTDAERLLALLESLLE 78
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
86-152 1.23e-05

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 41.43  E-value: 1.23e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 121869       86 EILLLLitVRDGACGKELLQDLrrlfgaDLSPGTVYPHLNDLAVEGVLEVQKLSKRKVYRLSDPEGA 152
Cdd:smart00418   1 KILKLL--AEGELCVCELAEIL------GLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVA 59
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 100-148 1.29e-04

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 38.77  E-value: 1.29e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 121869     100 GKELLQDLRRLFGA--DLSPGTVYPHLNDLAVEGVLEVQKL-----SKRKVYRLSD 148
Cdd:pfam03551  12 GYEIIKELEELSGGfwRPSEGTLYPILKRLEKEGLVESEWVdsgggPPRKYYRLTD 67
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
83-148 5.63e-08

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 48.78  E-value: 5.63e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 121869    83 HIDEILLLLITVRDgACGKELLQDLRRLFGA--DLSPGTVYPHLNDLAVEGVLEVQKLS-----KRKVYRLSD 148
Cdd:COG1695   9 TLELLILALLAEGP-MYGYEIIKELEERSGGfwKVSEGTLYPALKRLEKEGLVESEWEEseggpRRKYYRLTE 80
COG3398 COG3398
Predicted transcriptional regulator, contains two HTH domains [Transcription];
86-150 5.31e-06

Predicted transcriptional regulator, contains two HTH domains [Transcription];


Pssm-ID: 442625 [Multi-domain]  Cd Length: 159  Bit Score: 44.48  E-value: 5.31e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 121869    86 EILLLLITvRDGACGKELLQDLrrlfgaDLSPGTVYPHLNDLAVEGVLEVQKLSKRKVYRLSDPE 150
Cdd:COG3398 101 RILLYLLE-NPGATNKELAEEL------GISRSTVSWHLKRLEEDGLVERERDGRNVRYYLNPPE 158
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 86-161 5.52e-06

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 42.67  E-value: 5.52e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 121869    86 EILLLLitVRDGACGKELLQDLrrlfgaDLSPGTVYPHLNDLAVEGVLEVQKLSKRKVYRLSDPEGAFTRIDHMVD 161
Cdd:cd00090  11 RILRLL--LEGPLTVSELAERL------GLSQSTVSRHLKKLEEAGLVESRREGRRVYYSLTDAERLLALLESLLE 78
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
86-152 1.23e-05

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 41.43  E-value: 1.23e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 121869       86 EILLLLitVRDGACGKELLQDLrrlfgaDLSPGTVYPHLNDLAVEGVLEVQKLSKRKVYRLSDPEGA 152
Cdd:smart00418   1 KILKLL--AEGELCVCELAEIL------GLSQSTVSHHLKKLREAGLVESRREGKRVYYSLTDEKVA 59
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 100-148 1.29e-04

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 38.77  E-value: 1.29e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 121869     100 GKELLQDLRRLFGA--DLSPGTVYPHLNDLAVEGVLEVQKL-----SKRKVYRLSD 148
Cdd:pfam03551  12 GYEIIKELEELSGGfwRPSEGTLYPILKRLEKEGLVESEWVdsgggPPRKYYRLTD 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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