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Conserved domains on  [gi|3287967|sp|P10547|]
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RecName: Full=Lysostaphin; AltName: Full=Glycyl-glycine endopeptidase; Flags: Precursor

Protein Classification

Peptidase_M23 and SH3 domain-containing protein( domain architecture ID 10480300)

Peptidase_M23 and SH3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpD COG0739
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell ...
 264-384 7.05e-41

Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440502 [Multi-domain]  Cd Length: 196  Bit Score: 145.50  E-value: 7.05e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  264 GYGYGPYPLGINGGMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIGLIENDGVhRQWYMHLSKYNVKVGDYVKA 343
Cdd:COG0739  82 GFGYRRHPVTGRRRFHKGIDIAAPTGTPVYAAADGTVVFAGW-NGGYGNLVIIDHGNGY-TTLYAHLSSILVKVGQRVKA 159

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 3287967  344 GQIIGWSGSTGYSTAPHLHFQRMVnsfsNSTAQDPMPFLKS 384
Cdd:COG0739 160 GQVIGYVGNTGRSTGPHLHFEVRV----NGKPVDPLPFLPA 196
SH3 super family cl17036
Src Homology 3 domain superfamily; Src Homology 3 (SH3) domains are protein interaction ...
 411-475 1.18e-19

Src Homology 3 domain superfamily; Src Homology 3 (SH3) domains are protein interaction domains that bind proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs. Thus, they are referred to as proline-recognition domains (PRDs). SH3 domains are less selective and show more diverse specificity compared to other PRDs. They have been shown to bind peptide sequences that lack the PxxP motif; examples include the PxxDY motif of Eps8 and the RKxxYxxY sequence in SKAP55. SH3 domain containing proteins play versatile and diverse roles in the cell, including the regulation of enzymes, changing the subcellular localization of signaling pathway components, and mediating the formation of multiprotein complex assemblies, among others. Many members of this superfamily are adaptor proteins that associate with a number of protein partners, facilitating complex formation and signal transduction.


The actual alignment was detected with superfamily member pfam08460:

Pssm-ID: 473055 [Multi-domain]  Cd Length: 68  Bit Score: 82.82  E-value: 1.18e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3287967    411 YKSESASFT--PNTDIITRTTGPFRSMPQSGVLKAGQTIHYDEVMKQDGHVWVGYTGNSGQRIYLPV 475
Cdd:pfam08460   2 YPSEQGTFTigGKTGIVLRKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
rne super family cl35953
ribonuclease E; Reviewed
 44-226 2.38e-12

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 69.68  E-value: 2.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     44 VSKKVAEVETSkAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVEN---TAEVETSKAPVENTAEVETSK 120
Cdd:PRK10811  843 IRYPVVRPQDV-QVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEpvvVAEPQPEEVVVVETTHPEVIA 921

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    121 APV-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVEtSKAPVENTAEVETSKA 199
Cdd:PRK10811  922 APVtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP-VVAEVAAEVETVTAVE 998

                         170       180
                  ....*....|....*....|....*...
gi 3287967    200 PVENTAEVetSKAPVENT-AEVETSKAP 226
Cdd:PRK10811  999 PEVAPAQV--PEATVEHNhATAPMTRAP 1024
 
Name Accession Description Interval E-value
NlpD COG0739
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell ...
 264-384 7.05e-41

Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440502 [Multi-domain]  Cd Length: 196  Bit Score: 145.50  E-value: 7.05e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  264 GYGYGPYPLGINGGMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIGLIENDGVhRQWYMHLSKYNVKVGDYVKA 343
Cdd:COG0739  82 GFGYRRHPVTGRRRFHKGIDIAAPTGTPVYAAADGTVVFAGW-NGGYGNLVIIDHGNGY-TTLYAHLSSILVKVGQRVKA 159

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 3287967  344 GQIIGWSGSTGYSTAPHLHFQRMVnsfsNSTAQDPMPFLKS 384
Cdd:COG0739 160 GQVIGYVGNTGRSTGPHLHFEVRV----NGKPVDPLPFLPA 196
Peptidase_M23 pfam01551
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ...
 277-378 3.11e-34

Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.


Pssm-ID: 460250 [Multi-domain]  Cd Length: 96  Bit Score: 123.81  E-value: 3.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    277 GMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIGLIENDGVHrQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYS 356
Cdd:pfam01551   1 RFHKGIDIAAPTGTPVYAAADGVVVFAGW-LGGYGNLVIIDHGNGYS-TLYAHLSSILVKVGQRVKAGQVIGTVGSTGRS 78

                          90       100
                  ....*....|....*....|..
gi 3287967    357 TAPHLHFQRMVnsfsNSTAQDP 378
Cdd:pfam01551  79 TGPHLHFEIRK----NGKPVDP 96
M23_peptidase cd12797
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; ...
 279-364 1.35e-33

M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; This model describes the metallopeptidase M23 family, which includes beta-lytic metallopeptidase and lysostaphin. Members of this family are zinc endopeptidases that lyse bacterial cell wall peptidoglycans; they cleave either the N-acylmuramoyl-Ala bond between the cell wall peptidoglycan and the cross-linking peptide (e.g. beta-lytic endopeptidase) or a bond within the cross-linking peptide (e.g. stapholysin, and lysostaphin). Beta-lytic metallopeptidase, formerly known as beta-lytic protease, has a preference for cleavage of Gly-X bonds and favors hydrophobic or apolar residues on either side. It inhibits growth of sensitive organisms and may potentially serve as an antimicrobial agent. Lysostaphin, produced by Staphylococcus genus, cleaves pentaglycine cross-bridges of cell wall peptidoglycan, acting as autolysins to maintain cell wall metabolism or as toxins and weapons against competing strains. Staphylolysin (also known as LasA) is implicated in a range of processes related to Pseudomonas virulence, including stimulating shedding of the ectodomain of cell surface heparan sulphate proteoglycan syndecan-1, and elastin degradation in connective tissue. Its active site is less constricted and contains a five-coordinate zinc ion with trigonal bipyramidal geometry and two metal-bound water molecules, possibly contributing to its activity against a wider range of substrates than those used by related lytic enzymes, consistent with its multiple roles in Pseudomonas virulence. The family includes members that do not appear to have the conserved zinc-binding site and might be lipoproteins lacking proteolytic activity.


Pssm-ID: 410984 [Multi-domain]  Cd Length: 85  Bit Score: 121.93  E-value: 1.35e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNyGGGNQIgLIENDGVHRQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYSTA 358
Cdd:cd12797   1 HNGIDIAAPEGTPVYAAADGTVVFAGWDG-GYGNYV-IIDHGNGYYTLYAHLSSILVKVGQRVKKGQVIGTVGNTGRSTG 78


                ....*.
gi 3287967  359 PHLHFQ 364
Cdd:cd12797  79 PHLHFE 84
SH3_5 pfam08460
Bacterial SH3 domain;
411-475 1.18e-19

Bacterial SH3 domain;


Pssm-ID: 430010 [Multi-domain]  Cd Length: 68  Bit Score: 82.82  E-value: 1.18e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3287967    411 YKSESASFT--PNTDIITRTTGPFRSMPQSGVLKAGQTIHYDEVMKQDGHVWVGYTGNSGQRIYLPV 475
Cdd:pfam08460   2 YPSEQGTFTigGKTGIVLRKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
PRK11649 PRK11649
putative peptidase; Provisional
 279-368 1.01e-16

putative peptidase; Provisional


Pssm-ID: 236946 [Multi-domain]  Cd Length: 439  Bit Score: 82.41  E-value: 1.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNyGGGNQIGLiendgVH-RQW---YMHLSKYNVKVGDYVKAGQIIGWSGSTG 354
Cdd:PRK11649 313 HRGVDFAMPVGTPVLAVGDGEVVVAKRSG-AAGNYVAI-----RHgRQYttrYMHLRKLLVKPGQKVKRGDRIALSGNTG 386

                         90
                 ....*....|....
gi 3287967   355 YSTAPHLHFQRMVN 368
Cdd:PRK11649 387 RSTGPHLHYEVWIN 400
rne PRK10811
ribonuclease E; Reviewed
 44-226 2.38e-12

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 69.68  E-value: 2.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     44 VSKKVAEVETSkAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVEN---TAEVETSKAPVENTAEVETSK 120
Cdd:PRK10811  843 IRYPVVRPQDV-QVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEpvvVAEPQPEEVVVVETTHPEVIA 921

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    121 APV-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVEtSKAPVENTAEVETSKA 199
Cdd:PRK10811  922 APVtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP-VVAEVAAEVETVTAVE 998

                         170       180
                  ....*....|....*....|....*...
gi 3287967    200 PVENTAEVetSKAPVENT-AEVETSKAP 226
Cdd:PRK10811  999 PEVAPAQV--PEATVEHNhATAPMTRAP 1024
SH3b smart00287
Bacterial SH3 domain homologues;
413-480 4.26e-09

Bacterial SH3 domain homologues;


Pssm-ID: 214600 [Multi-domain]  Cd Length: 63  Bit Score: 52.72  E-value: 4.26e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3287967     413 SESASFTpNTDIITRTtGPFRSMPQSGVLKAGQTIHYDEVmkqDGHVWVGYTGNSGQRIYLPVRTWNK 480
Cdd:smart00287   1 SETAVVT-GDGLNVRT-GPGTSSPIIGTLKKGDKVKVLGV---DGQDWAKITYGSGQRGYVPGYVVNT 63
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 135-227 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    135 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 214
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    215 ENTAEVETSKAPV 227
Cdd:pfam20481  84 DNKTSETASSIPV 96
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 42-160 9.77e-04

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 9.77e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   42 MDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVET-----SKAPVENTAEVETSKAPVEnTAEVETSKAPVENTAEV 116
Cdd:COG3266 243 RLVLLLLIIGSALKAPSQASSASAPATTSLGEQQEVSLppavaAQPAAAAAAQPSAVALPAA-PAAAAAAAAPAEAAAPQ 321

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 3287967  117 ETSKAPVENTAEVETSKAPventAEVETSKAPVENTAEVETSKA 160
Cdd:COG3266 322 PTAAKPVVTETAAPAAPAP----EAAAAAAAPAAPAVAKKLAAD 361
 
Name Accession Description Interval E-value
NlpD COG0739
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell ...
 264-384 7.05e-41

Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440502 [Multi-domain]  Cd Length: 196  Bit Score: 145.50  E-value: 7.05e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  264 GYGYGPYPLGINGGMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIGLIENDGVhRQWYMHLSKYNVKVGDYVKA 343
Cdd:COG0739  82 GFGYRRHPVTGRRRFHKGIDIAAPTGTPVYAAADGTVVFAGW-NGGYGNLVIIDHGNGY-TTLYAHLSSILVKVGQRVKA 159

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 3287967  344 GQIIGWSGSTGYSTAPHLHFQRMVnsfsNSTAQDPMPFLKS 384
Cdd:COG0739 160 GQVIGYVGNTGRSTGPHLHFEVRV----NGKPVDPLPFLPA 196
Peptidase_M23 pfam01551
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ...
 277-378 3.11e-34

Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.


Pssm-ID: 460250 [Multi-domain]  Cd Length: 96  Bit Score: 123.81  E-value: 3.11e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    277 GMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIGLIENDGVHrQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYS 356
Cdd:pfam01551   1 RFHKGIDIAAPTGTPVYAAADGVVVFAGW-LGGYGNLVIIDHGNGYS-TLYAHLSSILVKVGQRVKAGQVIGTVGSTGRS 78

                          90       100
                  ....*....|....*....|..
gi 3287967    357 TAPHLHFQRMVnsfsNSTAQDP 378
Cdd:pfam01551  79 TGPHLHFEIRK----NGKPVDP 96
M23_peptidase cd12797
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; ...
 279-364 1.35e-33

M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; This model describes the metallopeptidase M23 family, which includes beta-lytic metallopeptidase and lysostaphin. Members of this family are zinc endopeptidases that lyse bacterial cell wall peptidoglycans; they cleave either the N-acylmuramoyl-Ala bond between the cell wall peptidoglycan and the cross-linking peptide (e.g. beta-lytic endopeptidase) or a bond within the cross-linking peptide (e.g. stapholysin, and lysostaphin). Beta-lytic metallopeptidase, formerly known as beta-lytic protease, has a preference for cleavage of Gly-X bonds and favors hydrophobic or apolar residues on either side. It inhibits growth of sensitive organisms and may potentially serve as an antimicrobial agent. Lysostaphin, produced by Staphylococcus genus, cleaves pentaglycine cross-bridges of cell wall peptidoglycan, acting as autolysins to maintain cell wall metabolism or as toxins and weapons against competing strains. Staphylolysin (also known as LasA) is implicated in a range of processes related to Pseudomonas virulence, including stimulating shedding of the ectodomain of cell surface heparan sulphate proteoglycan syndecan-1, and elastin degradation in connective tissue. Its active site is less constricted and contains a five-coordinate zinc ion with trigonal bipyramidal geometry and two metal-bound water molecules, possibly contributing to its activity against a wider range of substrates than those used by related lytic enzymes, consistent with its multiple roles in Pseudomonas virulence. The family includes members that do not appear to have the conserved zinc-binding site and might be lipoproteins lacking proteolytic activity.


Pssm-ID: 410984 [Multi-domain]  Cd Length: 85  Bit Score: 121.93  E-value: 1.35e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNyGGGNQIgLIENDGVHRQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYSTA 358
Cdd:cd12797   1 HNGIDIAAPEGTPVYAAADGTVVFAGWDG-GYGNYV-IIDHGNGYYTLYAHLSSILVKVGQRVKKGQVIGTVGNTGRSTG 78


                ....*.
gi 3287967  359 PHLHFQ 364
Cdd:cd12797  79 PHLHFE 84
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 266-383 7.59e-22

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 97.14  E-value: 7.59e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  266 GYGPYPLGinGGMHYGVDFFMNIGTPVKAISSGKIVEAGWsNYGGGNQIgLIENDGVHRQWYMHLSKYNVKVGDYVKAGQ 345
Cdd:COG4942 266 RFGERDGG--GGRNKGIDIAAPPGAPVRAVADGTVVYAGW-LRGYGNLV-IIDHGGGYLTLYAHLSSLLVKVGQRVKAGQ 341

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 3287967  346 IIGWSGSTGYSTAPHLHFQ-RMvnsfsNSTAQDPMPFLK 383
Cdd:COG4942 342 PIGTVGSSGGQGGPTLYFElRK-----NGKPVDPLPWLA 375
SH3_5 pfam08460
Bacterial SH3 domain;
411-475 1.18e-19

Bacterial SH3 domain;


Pssm-ID: 430010 [Multi-domain]  Cd Length: 68  Bit Score: 82.82  E-value: 1.18e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 3287967    411 YKSESASFT--PNTDIITRTTGPFRSMPQSGVLKAGQTIHYDEVMKQDGHVWVGYTGNSGQRIYLPV 475
Cdd:pfam08460   2 YPSEQGTFTigGKTGIVLRKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
SpoIIQ2 COG5821
Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family [Cell ...
 279-383 2.89e-19

Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444523 [Multi-domain]  Cd Length: 200  Bit Score: 85.85  E-value: 2.89e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNYGGgNQIgLIENDGVHRQWYMHL-SKYNVKVGDYVKAGQIIGWSGSTG--- 354
Cdd:COG5821  97 HTGIDIAAKEGTPVKAAADGVVVEVGKDPKYG-ITV-VIDHGNGIKTVYANLdSKIKVKVGQKVKKGQVIGKVGSTAlfe 174

                        90       100
                ....*....|....*....|....*....
gi 3287967  355 YSTAPHLHFQRMVnsfsNSTAQDPMPFLK 383
Cdd:COG5821 175 SSEGPHLHFEVLK----NGKPVDPMKYLK 199
PRK11649 PRK11649
putative peptidase; Provisional
 279-368 1.01e-16

putative peptidase; Provisional


Pssm-ID: 236946 [Multi-domain]  Cd Length: 439  Bit Score: 82.41  E-value: 1.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNyGGGNQIGLiendgVH-RQW---YMHLSKYNVKVGDYVKAGQIIGWSGSTG 354
Cdd:PRK11649 313 HRGVDFAMPVGTPVLAVGDGEVVVAKRSG-AAGNYVAI-----RHgRQYttrYMHLRKLLVKPGQKVKRGDRIALSGNTG 386

                         90
                 ....*....|....
gi 3287967   355 YSTAPHLHFQRMVN 368
Cdd:PRK11649 387 RSTGPHLHYEVWIN 400
rne PRK10811
ribonuclease E; Reviewed
 44-226 2.38e-12

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 69.68  E-value: 2.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     44 VSKKVAEVETSkAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVEN---TAEVETSKAPVENTAEVETSK 120
Cdd:PRK10811  843 IRYPVVRPQDV-QVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEpvvVAEPQPEEVVVVETTHPEVIA 921

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    121 APV-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVEtSKAPVENTAEVETSKA 199
Cdd:PRK10811  922 APVtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP-VVAEVAAEVETVTAVE 998

                         170       180
                  ....*....|....*....|....*...
gi 3287967    200 PVENTAEVetSKAPVENT-AEVETSKAP 226
Cdd:PRK10811  999 PEVAPAQV--PEATVEHNhATAPMTRAP 1024
rne PRK10811
ribonuclease E; Reviewed
 69-233 4.26e-12

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 68.91  E-value: 4.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     69 APVENTAEVETSKAPvENTAEVETSKAPVENTAEVETSKAPVENTAEVEtsKAPVENTAEVETSKAPVEnTAEVETSKAP 148
Cdd:PRK10811  848 VRPQDVQVEEQREAE-EVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVV--EEPVVVAEPQPEEVVVVE-TTHPEVIAAP 923

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    149 V-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVEtSKAPVENTAEVETSKAPV 227
Cdd:PRK10811  924 VtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP-VVAEVAAEVETVTAVEPE 1000


                  ....*.
gi 3287967    228 ENTAEV 233
Cdd:PRK10811 1001 VAPAQV 1006
rne PRK10811
ribonuclease E; Reviewed
 83-254 1.49e-11

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 66.99  E-value: 1.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     83 PVENTAEVETskapVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVEN---TAEVETSKAPVENTAEVETSK 159
Cdd:PRK10811  846 PVVRPQDVQV----EEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEpvvVAEPQPEEVVVVETTHPEVIA 921

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    160 APV-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVEtSKAPVENTAEVETSKA 238
Cdd:PRK10811  922 APVtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP-VVAEVAAEVETVTAVE 998

                         170
                  ....*....|....*.
gi 3287967    239 LVQNRTALRAATHEHS 254
Cdd:PRK10811  999 PEVAPAQVPEATVEHN 1014
rne PRK10811
ribonuclease E; Reviewed
 31-213 3.04e-10

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 62.75  E-value: 3.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     31 QNETHASEKSNMDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV-ENTAEVETSKAP 109
Cdd:PRK10811  858 QREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVtEQPQVITESDVA 937

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    110 VEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVetskaPVENTAEVETSKAPVEntAEVETSKAPVE 189
Cdd:PRK10811  938 VA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAA-----PVVAEVAAEVETVTAV--EPEVAPAQVPE 1008

                         170       180
                  ....*....|....*....|....
gi 3287967    190 NTAEVETSKAPVentaevetSKAP 213
Cdd:PRK10811 1009 ATVEHNHATAPM--------TRAP 1024
SH3b smart00287
Bacterial SH3 domain homologues;
413-480 4.26e-09

Bacterial SH3 domain homologues;


Pssm-ID: 214600 [Multi-domain]  Cd Length: 63  Bit Score: 52.72  E-value: 4.26e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 3287967     413 SESASFTpNTDIITRTtGPFRSMPQSGVLKAGQTIHYDEVmkqDGHVWVGYTGNSGQRIYLPVRTWNK 480
Cdd:smart00287   1 SETAVVT-GDGLNVRT-GPGTSSPIIGTLKKGDKVKVLGV---DGQDWAKITYGSGQRGYVPGYVVNT 63
rne PRK10811
ribonuclease E; Reviewed
 108-256 3.50e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 56.20  E-value: 3.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    108 APVENTAEVETSKAPvENTAEVETSKAPVENTAEVETSKAPVENTAEVEtsKAPVENTAEVETSKAPVEnTAEVETSKAP 187
Cdd:PRK10811  848 VRPQDVQVEEQREAE-EVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVV--EEPVVVAEPQPEEVVVVE-TTHPEVIAAP 923

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    188 V-ENTAEVETSKAPVEntAEVETSKAPVENTAEVETSKAPVENTAEVETSKALVQNRTALRAATHEHSAQ 256
Cdd:PRK10811  924 VtEQPQVITESDVAVA--QEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEV 991
PRK11637 PRK11637
AmiB activator; Provisional
 289-382 5.11e-07

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 52.00  E-value: 5.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   289 GTPVKAISSGKIVEAGW-SNYGggnQIGLIEndgvHRQWYMHLSKYN----VKVGDYVKAGQIIGWSGSTGYSTAPHLHF 363
Cdd:PRK11637 339 GTEVKAIADGRVLLADWlQGYG---LVVVVE----HGKGDMSLYGYNqsalVSVGAQVRAGQPIALVGSSGGQGRPSLYF 411

                         90       100
                 ....*....|....*....|....
gi 3287967   364 Q-----RMVNsfsnstaqdPMPFL 382
Cdd:PRK11637 412 EirrqgQAVN---------PQPWL 426
SpoIVFA COG5833
Stage IV sporulation protein SpoIVFA, regulates SpoIVFB [Cell cycle control, cell division, ...
 279-363 1.71e-06

Stage IV sporulation protein SpoIVFA, regulates SpoIVFB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444535 [Multi-domain]  Cd Length: 219  Bit Score: 48.83  E-value: 1.71e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  279 HYGVDFFMNIGTPVKAISSGKIVEAGWSNyGGGNQIgLIENDGVHRQWYMHLSKYNVKVGDYVKAGQIIGwSGSTGYSTA 358
Cdd:COG5833 120 GKGVDIETPGGANVKAVKEGYVIFAGKDE-ETGKTV-IIQHADGSESWYGNLSSIDVKLYDFVEAGQKIG-TVPATEGEE 196


                ....*
gi 3287967  359 PHLHF 363
Cdd:COG5833 197 GTFYF 201
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 48-219 3.16e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 49.71  E-value: 3.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    48 VAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKA-----PVENTA------------EVETSKAPV 110
Cdd:PRK08691 371 VIENTELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEgktagPVSNQEnndvppwedapdEAQTAAGTA 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   111 ENTAEVETSKAPVENTAEVETSK-APVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVE 189
Cdd:PRK08691 451 QTSAKSIQTASEAETPPENQVSKnKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDNDCPPE 530

                        170       180       190
                 ....*....|....*....|....*....|
gi 3287967   190 NTAEVetSKAPVENTAEVETSKAPVENTAE 219
Cdd:PRK08691 531 DGAEI--PPPDWEHAAPADTAGGGADEEAE 558
PRK06148 PRK06148
hypothetical protein; Provisional
 268-364 3.22e-06

hypothetical protein; Provisional


Pssm-ID: 180426 [Multi-domain]  Cd Length: 1013  Bit Score: 50.02  E-value: 3.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    268 GPYPLGINGGMHYGVDFFMNIGTPVKAISSGKI----VEAGWSNYGGgnqIGLIEndgvHR--------QWYMHLSKYNV 335
Cdd:PRK06148  430 SRFIEGERRTVHLGVDLFAPAGTPVYAPLAGTVrsveIEAVPLGYGG---LVALE----HEtpggdpfyTLYGHLAHEAV 502

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 3287967    336 ---KVGDYVKAGQIIGWSGST----GYstAPHLHFQ 364
Cdd:PRK06148  503 srlKPGDRLAAGELFGAMGDAhengGW--APHLHFQ 536
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 135-227 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    135 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 214
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    215 ENTAEVETSKAPV 227
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 122-214 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    122 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 201
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    202 ENTAEVETSKAPV 214
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 109-201 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    109 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 188
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    189 ENTAEVETSKAPV 201
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 96-188 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     96 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 175
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    176 ENTAEVETSKAPV 188
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 70-162 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     70 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 149
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    150 ENTAEVETSKAPV 162
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 57-149 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     57 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 136
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    137 ENTAEVETSKAPV 149
Cdd:pfam20481  84 DNKTSETASSIPV 96
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 83-175 5.34e-06

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 45.07  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     83 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 162
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83

                          90
                  ....*....|...
gi 3287967    163 ENTAEVETSKAPV 175
Cdd:pfam20481  84 DNKTSETASSIPV 96
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 57-249 5.66e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 49.09  E-value: 5.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    57 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 136
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   137 ENTAEVETSKaPVENTAEVETSKAPVENTAEvetsKAPVENTAEVETSKAPVENTAEVETskAPVENTAEVETSKAPVEN 216
Cdd:PRK07994 441 SEPAAASRAR-PVNSALERLASVRPAPSALE----KAPAKKEAYRWKATNPVEVKKEPVA--TPKALKKALEHEKTPELA 513

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 3287967   217 TAEVETSKAPVENTAEVETSK--ALVQNrTALRAA 249
Cdd:PRK07994 514 AKLAAEAIERDPWAALVSQLGlpGLVEQ-LALNAW 547
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 54-238 1.04e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 48.17  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    54 SKAPVENTaeveTSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKA-----PVENTAEVET---SKAPVEN 125
Cdd:PRK08691 368 ANAVIENT----ELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEgktagPVSNQENNDVppwEDAPDEA 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   126 TAEVETSKAPVENTAEVETSKAPVENtaEVETSKApVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTA 205
Cdd:PRK08691 444 QTAAGTAQTSAKSIQTASEAETPPEN--QVSKNKA-ADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGY 520

                        170       180       190
                 ....*....|....*....|....*....|...
gi 3287967   206 EVETSKAPVENTAEVetSKAPVENTAEVETSKA 238
Cdd:PRK08691 521 GFPDNDCPPEDGAEI--PPPDWEHAAPADTAGG 551
PTZ00121 PTZ00121
MAEBL; Provisional
 36-249 3.21e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     36 ASEKSNMDVSKKVAEVETSKAPVENTAEVETSKApventaevETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAE 115
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA--------DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    116 VETSKAPVENTAEVETSKAPVENTAEVETSKapveNTAEVETSKAPVENTAEVETSKAPVENTAEvETSKAPVENTAEvE 195
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAK----KKAEEAKKKADEAKKAAEAKKKADEAKKAE-EAKKADEAKKAE-E 1532

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 3287967    196 TSKAPVENTAEvETSKAPVENTAEvETSKAPVENTAEvETSKALVQNRTALRAA 249
Cdd:PTZ00121 1533 AKKADEAKKAE-EKKKADELKKAE-ELKKAEEKKKAE-EAKKAEEDKNMALRKA 1583
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 83-258 6.16e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 45.63  E-value: 6.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    83 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 162
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   163 ENTAEVETSKaPVENTAEVETSKAPVENTAEvetsKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKALVQn 242
Cdd:PRK07994 441 SEPAAASRAR-PVNSALERLASVRPAPSALE----KAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAA- 514

                        170
                 ....*....|....*.
gi 3287967   243 RTALRAATHEhsaQWL 258
Cdd:PRK07994 515 KLAAEAIERD---PWA 527
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 148-236 6.23e-05

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 41.99  E-value: 6.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    148 PVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPV 227
Cdd:pfam20481   4 PIDNKTNGTASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPI 83


                  ....*....
gi 3287967    228 ENTAEVETS 236
Cdd:pfam20481  84 DNKTSETAS 92
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 45-195 8.57e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 45.10  E-value: 8.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    45 SKKVAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAP--VENTAEVETSKAP 122
Cdd:PRK14949 636 GKKSSADRKPKTPPSRAPPASLSKPASSPDASQTSASFDLDPDFELATHQSVPEAALASGSAPAPppVPDPYDRPPWEEA 715

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 3287967   123 VENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVEntaEVETSKAPVENTAEVETSKAPVENTAEVE 195
Cdd:PRK14949 716 PEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQP---QVQAEAQSPASTTALTQTSSEVQDTELNL 785
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 33-219 8.58e-05

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 45.16  E-value: 8.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     33 ETHASEKSNMDVSKKVAE--VETSKAPVENTAEvETSKAPVENTAEvETSKAPVENTAEvETSKAPVENTAEVETSKAPV 110
Cdd:PTZ00341  948 EEDAEENVEEDAEENVEEnvEENVEENVEENVE-ENVEENVEENVE-ENVEENVEENIE-ENVEENVEENIEENVEEYDE 1024

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    111 ENTAEVETS--KAPVENTAEVE-TSKAPVENTAEVETSKAPVENTAEVETSkapVENTAEVETSKAPVENTAEVETS-KA 186
Cdd:PTZ00341 1025 ENVEEVEENveEYDEENVEEIEeNAEENVEENIEENIEEYDEENVEEIEEN---IEENIEENVEENVEENVEEIEENvEE 1101

                         170       180       190
                  ....*....|....*....|....*....|...
gi 3287967    187 PVENTAEvETSKAPVENTAEVETSKAPVENTAE 219
Cdd:PTZ00341 1102 NVEENAE-ENAEENAEENAEEYDDENPEEHNEE 1133
PTZ00121 PTZ00121
MAEBL; Provisional
 36-238 1.66e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     36 ASEKSNMDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAE----VETSKAPVENTAEVETSKAPVE 111
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEkaeaAEKKKEEAKKKADAAKKKAEEK 1390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    112 NTAEvETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENT 191
Cdd:PTZ00121 1391 KKAD-EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 3287967    192 AEVETSKAPVENTAEVETSKapveNTAEVETSKAPVENTAEVETSKA 238
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKADEAK----KKAEEAKKKADEAKKAAEAKKKA 1512
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 22-257 1.79e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 44.39  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     22 LASIV---YGGIQNETHASEKSNMDVSKKVA-EVETSKAPVENTAEV------ETSKAPVENTAEVETSKAPVENTAE-- 89
Cdd:PTZ00341  888 LANAIekyAGGGKKDKKAKKKDAKDLSGNIAhEINLINKELKNQNENvpehlkEHAEANIEEDAEENVEEDAEENVEEnv 967

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     90 VETSKAPVENTAEvETSKAPVENTAEvETSKAPVENTAEvETSKAPVENTAEVETSKAPVENTAEVETS--KAPVENTAE 167
Cdd:PTZ00341  968 EENVEENVEENVE-ENVEENVEENVE-ENVEENVEENIE-ENVEENVEENIEENVEEYDEENVEEVEENveEYDEENVEE 1044

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    168 VE-TSKAPVENTAEVETSKAPVENTAEVETSkapVENTAEVETSKAPVENTAEVETS-KAPVENTAEVETSKALVQNRTA 245
Cdd:PTZ00341 1045 IEeNAEENVEENIEENIEEYDEENVEEIEEN---IEENIEENVEENVEENVEEIEENvEENVEENAEENAEENAEENAEE 1121

                         250
                  ....*....|...
gi 3287967    246 LRAAT-HEHSAQW 257
Cdd:PTZ00341 1122 YDDENpEEHNEEY 1134
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 52-136 2.67e-04

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 40.06  E-value: 2.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967     52 ETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVET 131
Cdd:pfam20481  12 TASSIPVDSKNEETASSIPIDSTNNETASSIPIDNKTTETASSIPIDSSNSETAASIPIDNTNNSTASSIPIDNKTSETA 91


                  ....*
gi 3287967    132 SKAPV 136
Cdd:pfam20481  92 SSIPV 96
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 48-218 2.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 43.70  E-value: 2.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967    48 VAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTAEVETSKAPVENTA 127
Cdd:PRK07994 365 LPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPA 444

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   128 EVETSKaPVENTAEVETSKAPVENTAEVETSKA---------PVENTAEVETskAPVENTAEVETSKAPVENTAEVETSK 198
Cdd:PRK07994 445 AASRAR-PVNSALERLASVRPAPSALEKAPAKKeayrwkatnPVEVKKEPVA--TPKALKKALEHEKTPELAAKLAAEAI 521

                        170       180
                 ....*....|....*....|..
gi 3287967   199 APVENTAEVETSKAP--VENTA 218
Cdd:PRK07994 522 ERDPWAALVSQLGLPglVEQLA 543
OapA COG3061
Cell division protein YtfB/OapA (opacity-associated protein A) [Cell cycle control, cell ...
 266-368 5.07e-04

Cell division protein YtfB/OapA (opacity-associated protein A) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442295 [Multi-domain]  Cd Length: 425  Bit Score: 42.35  E-value: 5.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  266 GYGPYPLGINGGMHYGVDFFMNIGTPVKAIssGKIVEAGWSNYGGGNQIGLIENDGVHRQWYMHLSKYNVKVGDYVKAGQ 345
Cdd:COG3061 297 GGGGHKITRRGGGGGGAAVGVGTGTPTTGA--GLGVVRGGRGGGGGVVVGQIGRGGTYGGTGLHLHKHGHKGGGVVGQGV 374

                        90       100
                ....*....|....*....|...
gi 3287967  346 IIGWSGSTGYSTAPHLHFQRMVN 368
Cdd:COG3061 375 TIGTLGGTGPTTGPHLHYEFVQN 397
nlpD PRK10871
murein hydrolase activator NlpD;
281-364 6.49e-04

murein hydrolase activator NlpD;


Pssm-ID: 236782 [Multi-domain]  Cd Length: 319  Bit Score: 41.74  E-value: 6.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   281 GVDFFMNIGTPVKAISSGKIVEAGWSNYGGGNQIGLIENDGvHRQWYMHLSKYNVKVGDYVKAGQIIGWSGSTGYSTApH 360
Cdd:PRK10871 221 GIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDD-YLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSST-R 298


                 ....
gi 3287967   361 LHFQ 364
Cdd:PRK10871 299 LHFE 302
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 42-160 9.77e-04

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 9.77e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   42 MDVSKKVAEVETSKAPVENTAEVETSKAPVENTAEVET-----SKAPVENTAEVETSKAPVEnTAEVETSKAPVENTAEV 116
Cdd:COG3266 243 RLVLLLLIIGSALKAPSQASSASAPATTSLGEQQEVSLppavaAQPAAAAAAQPSAVALPAA-PAAAAAAAAPAEAAAPQ 321

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 3287967  117 ETSKAPVENTAEVETSKAPventAEVETSKAPVENTAEVETSKA 160
Cdd:COG3266 322 PTAAKPVVTETAAPAAPAP----EAAAAAAAPAAPAVAKKLAAD 361
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 80-186 1.20e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.37  E-value: 1.20e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   80 SKAPVENTAEVETSKAPVENTAEVET-----SKAPVENTAEVETSKAPVEnTAEVETSKAPVENTAEVETSKAPVENTAE 154
Cdd:COG3266 255 LKAPSQASSASAPATTSLGEQQEVSLppavaAQPAAAAAAQPSAVALPAA-PAAAAAAAAPAEAAAPQPTAAKPVVTETA 333

                        90       100       110
                ....*....|....*....|....*....|..
gi 3287967  155 VETSKAPventAEVETSKAPVENTAEVETSKA 186
Cdd:COG3266 334 APAAPAP----EAAAAAAAPAAPAVAKKLAAD 361
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 106-212 1.20e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.37  E-value: 1.20e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  106 SKAPVENTAEVETSKAPVENTAEVET-----SKAPVENTAEVETSKAPVEnTAEVETSKAPVENTAEVETSKAPVENTAE 180
Cdd:COG3266 255 LKAPSQASSASAPATTSLGEQQEVSLppavaAQPAAAAAAQPSAVALPAA-PAAAAAAAAPAEAAAPQPTAAKPVVTETA 333

                        90       100       110
                ....*....|....*....|....*....|..
gi 3287967  181 VETSKAPventAEVETSKAPVENTAEVETSKA 212
Cdd:COG3266 334 APAAPAP----EAAAAAAAPAAPAVAKKLAAD 361
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 145-260 2.27e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 40.60  E-value: 2.27e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  145 SKAPVENTAEVETSKAPVENTAEVET-----SKAPVENTAEVETSKAPVEnTAEVETSKAPVENTAEVETSKAPVENTAE 219
Cdd:COG3266 255 LKAPSQASSASAPATTSLGEQQEVSLppavaAQPAAAAAAQPSAVALPAA-PAAAAAAAAPAEAAAPQPTAAKPVVTETA 333

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 3287967  220 VETSKAPVENTAEVETSKALVQNRTAlraatheHSAQWLNN 260
Cdd:COG3266 334 APAAPAPEAAAAAAAPAAPAVAKKLA-------ADEQWLAS 367
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
56-241 7.78e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 38.70  E-value: 7.78e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   56 APVENTAEVETSKApvENTAEVETSKApventaEVETSKAPVENTAEVETSKApVENTAEVETSKApvENTAEVETSKAP 135
Cdd:COG2268 195 AEIIRDARIAEAEA--ERETEIAIAQA------NREAEEAELEQEREIETARI-AEAEAELAKKKA--EERREAETARAE 263

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  136 VENTAEVETSKAPVENTAEVETskapVENTAEVETSKAPVENTAEVEtsKAPVENTAEVETSKAPVENTAEVETSKApvE 215
Cdd:COG2268 264 AEAAYEIAEANAEREVQRQLEI----AEREREIELQEKEAEREEAEL--EADVRKPAEAEKQAAEAEAEAEAEAIRA--K 335

                       170       180
                ....*....|....*....|....*.
gi 3287967  216 NTAEVETSKApvENTAEVETSKALVQ 241
Cdd:COG2268 336 GLAEAEGKRA--LAEAWNKLGDAAIL 359
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
69-242 8.87e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 38.32  E-value: 8.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967   69 APVENTAEVETSKApvENTAEVETSKApventaEVETSKAPVENTAEVETSKApVENTAEVETSKApvENTAEVETSKAP 148
Cdd:COG2268 195 AEIIRDARIAEAEA--ERETEIAIAQA------NREAEEAELEQEREIETARI-AEAEAELAKKKA--EERREAETARAE 263

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3287967  149 VENTAEVETSKAPVENTAEVETskapVENTAEVETSKAPVENTAEVEtsKAPVENTAEVETSKAPVENTAEVETSKAPVE 228
Cdd:COG2268 264 AEAAYEIAEANAEREVQRQLEI----AEREREIELQEKEAEREEAEL--EADVRKPAEAEKQAAEAEAEAEAEAIRAKGL 337

                       170
                ....*....|....
gi 3287967  229 NTAEVETSKALVQN 242
Cdd:COG2268 338 AEAEGKRALAEAWN 351
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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