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Conserved domains on  [gi|129951|sp|P07585|]
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RecName: Full=Decorin; AltName: Full=Bone proteoglycan II; AltName: Full=PG-S2; AltName: Full=PG40; Flags: Precursor

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12183199)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
73-305 3.60e-26

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.10  E-value: 3.60e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    73 DKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskvspgAFTPLVKLERLYLSKNQLKELPEKMP--K 150
Cdd:COG4886  64 SLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELAnlT 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   151 TLQELRAHENEITKVRKVtFNGLNQMIVIELGTNPLKSsgIENgAFQGMKKLSYIRIADTNITSIPQGL--PPSLTELHL 228
Cdd:COG4886 137 NLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTD--LPE-ELGNLTNLKELDLSNNQITDLPEPLgnLTNLEELDL 212

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 129951   229 DGNKISRVDaASLKGLNNLAKLGLSFNSISAVDngSLANTPHLRELHLDNNKLTRVPgGLAEHKYIQVVYLHNNNIS 305
Cdd:COG4886 213 SGNQLTDLP-EPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLT 285
LRRNT smart00013
Leucine rich repeat N-terminal domain;
54-85 7.27e-13

Leucine rich repeat N-terminal domain;


:

Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 61.95  E-value: 7.27e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 129951       54 CPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTL 85
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
73-305 3.60e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.10  E-value: 3.60e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    73 DKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskvspgAFTPLVKLERLYLSKNQLKELPEKMP--K 150
Cdd:COG4886  64 SLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELAnlT 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   151 TLQELRAHENEITKVRKVtFNGLNQMIVIELGTNPLKSsgIENgAFQGMKKLSYIRIADTNITSIPQGL--PPSLTELHL 228
Cdd:COG4886 137 NLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTD--LPE-ELGNLTNLKELDLSNNQITDLPEPLgnLTNLEELDL 212

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 129951   229 DGNKISRVDaASLKGLNNLAKLGLSFNSISAVDngSLANTPHLRELHLDNNKLTRVPgGLAEHKYIQVVYLHNNNIS 305
Cdd:COG4886 213 SGNQLTDLP-EPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLT 285
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
70-298 5.92e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 73.19  E-value: 5.92e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     70 LGLDKVPKDLPPDTTLLDLQNNKITEIKDgdfknlkNLHALIlvnnkiskvspgaftplvklERLYLSKNQLKELPEKMP 149
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSLPE-------NLQGNI--------------------KTLYANSNQLTSIPATLP 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    150 KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIEngafqgmkKLSYIRIADTNITSIPQGLPPSLTELHLD 229
Cdd:PRK15370 241 DTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPE--------ELRYLSVYDNSIRTLPAHLPSGITHLNVQ 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    230 GNKISRVDAASLKGLNNLAKLGLSFNSI-----SAVDNGSLANT----------PHLRELHLDNNKLTRVPGGL-AEHKY 293
Cdd:PRK15370 313 SNSLTALPETLPPGLKTLEAGENALTSLpaslpPELQVLDVSKNqitvlpetlpPTITTLDVSRNALTNLPENLpAALQI 392


                 ....*
gi 129951    294 IQVVY 298
Cdd:PRK15370 393 MQASR 397
LRRNT smart00013
Leucine rich repeat N-terminal domain;
54-85 7.27e-13

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 61.95  E-value: 7.27e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 129951       54 CPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTL 85
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 84-285 1.01e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.73  E-value: 1.01e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    84 TLLDLQNNKITEIkdGDFKNLKNLHALILVNNKISKVSpgAFTPLVKLERLYLSKNQLKELP--EKMPKtLQELRAHENE 161
Cdd:cd21340   5 THLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGNR 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   162 ITKVrkvtfNGL-NQMIVIELgtnplkssgiengafqgmkKLSYIRIA-DTNITSIP---QGLPPSLTELHLDGNKISrv 236
Cdd:cd21340  80 ISVV-----EGLeNLTNLEEL-------------------HIENQRLPpGEKLTFDPrslAALSNSLRVLNISGNNID-- 133

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 129951   237 DAASLKGLNNLAKLGLSFNSISAVDN--GSLANTPHLRELHLDNNKLTRVP 285
Cdd:cd21340 134 SLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
84-141 1.62e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 59.08  E-value: 1.62e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 129951      84 TLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQL 141
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 54-80 2.84e-10

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 54.56  E-value: 2.84e-10
                          10        20
                  ....*....|....*....|....*..
gi 129951      54 CPFRCQCHLRVVQCSDLGLDKVPKDLP 80
Cdd:pfam01462   2 CPVPCHCSATVVNCSDRGLTAVPRDLP 28
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
73-305 3.60e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.10  E-value: 3.60e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    73 DKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKiskvspgAFTPLVKLERLYLSKNQLKELPEKMP--K 150
Cdd:COG4886  64 SLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELAnlT 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   151 TLQELRAHENEITKVRKVtFNGLNQMIVIELGTNPLKSsgIENgAFQGMKKLSYIRIADTNITSIPQGL--PPSLTELHL 228
Cdd:COG4886 137 NLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTD--LPE-ELGNLTNLKELDLSNNQITDLPEPLgnLTNLEELDL 212

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 129951   229 DGNKISRVDaASLKGLNNLAKLGLSFNSISAVDngSLANTPHLRELHLDNNKLTRVPgGLAEHKYIQVVYLHNNNIS 305
Cdd:COG4886 213 SGNQLTDLP-EPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLT 285
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
84-304 1.72e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 97.70  E-value: 1.72e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    84 TLLDLQNNKITEIKDgDFKNLKNLHALILVNNKISKVsPGAFTPLVKLERLYLSKNQLKELPE---KMPKtLQELRAHEN 160
Cdd:COG4886 116 ESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEelgNLTN-LKELDLSNN 192

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   161 EITKVrKVTFNGLNQMIVIELGTNPLKSsgiENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDaa 239
Cdd:COG4886 193 QITDL-PEPLGNLTNLEELDLSGNQLTD---LPEPLANLTNLETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP-- 266

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 129951   240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNI 304
Cdd:COG4886 267 PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLK 331
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
88-305 3.62e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 82.29  E-value: 3.62e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRK 167
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAaSLKGLN 245
Cdd:COG4886  81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELAnlTNLKELDLSNNQLTDLPE-PLGNLT 159

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   246 NLAKLGLSFNSISAVDNgSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNIS 305
Cdd:COG4886 160 NLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLT 218
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
70-298 5.92e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 73.19  E-value: 5.92e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     70 LGLDKVPKDLPPDTTLLDLQNNKITEIKDgdfknlkNLHALIlvnnkiskvspgaftplvklERLYLSKNQLKELPEKMP 149
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSLPE-------NLQGNI--------------------KTLYANSNQLTSIPATLP 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    150 KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIEngafqgmkKLSYIRIADTNITSIPQGLPPSLTELHLD 229
Cdd:PRK15370 241 DTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPE--------ELRYLSVYDNSIRTLPAHLPSGITHLNVQ 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    230 GNKISRVDAASLKGLNNLAKLGLSFNSI-----SAVDNGSLANT----------PHLRELHLDNNKLTRVPGGL-AEHKY 293
Cdd:PRK15370 313 SNSLTALPETLPPGLKTLEAGENALTSLpaslpPELQVLDVSKNqitvlpetlpPTITTLDVSRNALTNLPENLpAALQI 392


                 ....*
gi 129951    294 IQVVY 298
Cdd:PRK15370 393 MQASR 397
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
61-295 1.27e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.50  E-value: 1.27e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    61 HLRVVQCSDLGLDKVPKDLPPDTTL--LDLQNNKITEIKDgDFKNLKNLHALILVNNKISKVsPGAFTPLVKLERLYLSK 138
Cdd:COG4886 160 NLKSLDLSNNQLTDLPEELGNLTNLkeLDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSN 237

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   139 NQLKELPE--KMPKtLQELRAHENEITKVRKVTfnGLNQMIVIELGTNPLKSSGIEN-GAFQGMKKLSYIRIADTNITSI 215
Cdd:COG4886 238 NQLTDLPElgNLTN-LEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKElELLLGLNSLLLLLLLLNLLELL 314

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   216 PQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQ 295
Cdd:COG4886 315 ILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLL 394
LRRNT smart00013
Leucine rich repeat N-terminal domain;
54-85 7.27e-13

Leucine rich repeat N-terminal domain;


Pssm-ID: 214470 [Multi-domain]  Cd Length: 33  Bit Score: 61.95  E-value: 7.27e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 129951       54 CPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTL 85
Cdd:smart00013   2 CPAPCNCSGTAVDCSGRGLTEVPLDLPPDTTL 33
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 84-285 1.01e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.73  E-value: 1.01e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    84 TLLDLQNNKITEIkdGDFKNLKNLHALILVNNKISKVSpgAFTPLVKLERLYLSKNQLKELP--EKMPKtLQELRAHENE 161
Cdd:cd21340   5 THLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGNR 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   162 ITKVrkvtfNGL-NQMIVIELgtnplkssgiengafqgmkKLSYIRIA-DTNITSIP---QGLPPSLTELHLDGNKISrv 236
Cdd:cd21340  80 ISVV-----EGLeNLTNLEEL-------------------HIENQRLPpGEKLTFDPrslAALSNSLRVLNISGNNID-- 133

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 129951   237 DAASLKGLNNLAKLGLSFNSISAVDN--GSLANTPHLRELHLDNNKLTRVP 285
Cdd:cd21340 134 SLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
55-250 1.64e-12

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 68.57  E-value: 1.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     55 PFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDgdfKNLKNLHALILVNNKISKVsPGAFTPlvKLERL 134
Cdd:PRK15370 215 PENLQGNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPE---RLPSALQSLDLFHNKISCL-PENLPE--ELRYL 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    135 YLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNqmiVIELGTNPLKSsgIENGAFQGMKKLSyirIADTNITS 214
Cdd:PRK15370 289 SVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLK---TLEAGENALTS--LPASLPPELQVLD---VSKNQITV 360

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 129951    215 IPQGLPPSLTELHLDGNKISRVD---AASLKGL----NNLAKL 250
Cdd:PRK15370 361 LPETLPPTITTLDVSRNALTNLPenlPAALQIMqasrNNLVRL 403
LRR_8 pfam13855
Leucine rich repeat;
84-141 1.62e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 59.08  E-value: 1.62e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 129951      84 TLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQL 141
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
221-281 1.90e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.69  E-value: 1.90e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 129951     221 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 281
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRNT pfam01462
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 54-80 2.84e-10

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 396168 [Multi-domain]  Cd Length: 28  Bit Score: 54.56  E-value: 2.84e-10
                          10        20
                  ....*....|....*....|....*..
gi 129951      54 CPFRCQCHLRVVQCSDLGLDKVPKDLP 80
Cdd:pfam01462   2 CPVPCHCSATVVNCSDRGLTAVPRDLP 28
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 75-305 1.22e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.86  E-value: 1.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     75 VPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKelpEKMPKTLQE 154
Cdd:PLN00113 134 IPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLV---GQIPRELGQ 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    155 LRAheneiTKVRKVTFNGLNQMIVIELGtnplkssgiengafqGMKKLSYIRIADTNIT-SIPQGLpPSLTELH---LDG 230
Cdd:PLN00113 211 MKS-----LKWIYLGYNNLSGEIPYEIG---------------GLTSLNHLDLVYNNLTgPIPSSL-GNLKNLQylfLYQ 269

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 129951    231 NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT-RVPGGLAEHKYIQVVYLHNNNIS 305
Cdd:PLN00113 270 NKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFS 345
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 30-282 2.00e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 55.05  E-value: 2.00e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    30 EDEASGIGPEVPDDRDFEpslgpvcpfRCQCHLRVVQCSDLGLDKVPKDLPPDT--TLLDLQNNKITEIKDGDFKNL--- 104
Cdd:cd00116  37 EEAAKALASALRPQPSLK---------ELCLSLNETGRIPRGLQSLLQGLTKGCglQELDLSDNALGPDGCGVLESLlrs 107

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   105 KNLHALILVNNKISKvSPGAF------TPLVKLERLYLSKNQLK-ELPEKMPKTLQELRAHEneitkvrkvtfnglnqmi 177
Cdd:cd00116 108 SSLQELKLNNNGLGD-RGLRLlakglkDLPPALEKLVLGRNRLEgASCEALAKALRANRDLK------------------ 168

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   178 VIELGTNPLKSSGIENgAFQGMKKLSYIRIADTNITSI-PQGL---------PPSLTELHLDGNKISRVDAASL-----K 242
Cdd:cd00116 169 ELNLANNGIGDAGIRA-LAEGLKANCNLEVLDLNNNGLtDEGAsalaetlasLKSLEVLNLGDNNLTDAGAAALasallS 247

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 129951   243 GLNNLAKLGLSFNSISAVDNGSLA----NTPHLRELHLDNNKLT 282
Cdd:cd00116 248 PNISLLTLSLSCNDITDDGAKDLAevlaEKESLLELDLRGNKFG 291
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 75-312 8.51e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 54.08  E-value: 8.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     75 VPKDLPPDTTL--LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLK-ELPEkmpkt 151
Cdd:PLN00113 228 IPYEIGGLTSLnhLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIPE----- 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    152 lqelraheneitkvrkvtfnglnqmIVIElgtnplkssgiengafqgMKKLSYIRIADTNIT-SIPQGLP--PSLTELHL 228
Cdd:PLN00113 303 -------------------------LVIQ------------------LQNLEILHLFSNNFTgKIPVALTslPRLQVLQL 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    229 DGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL-TRVPGGLAEHKYIQVVYLHNNNISVV 307
Cdd:PLN00113 340 WSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSGE 419


                 ....*
gi 129951    308 GSSDF 312
Cdd:PLN00113 420 LPSEF 424
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 222-307 1.11e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.71  E-value: 1.11e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   222 SLTELHLDGNKISRVDAasLKGLNNLAKLGLSFNSISAVDNgsLANTPHLRELHLDNNKLTRVPgGLAEHKYIQVVYLHN 301
Cdd:cd21340   3 RITHLYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGG 77


                ....*.
gi 129951   302 NNISVV 307
Cdd:cd21340  78 NRISVV 83
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
221-310 2.15e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 52.24  E-value: 2.15e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   221 PSLTELHLDGNKisrvdaaSLKGLNNLAKLGLSFNSISAVDNgSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 300
Cdd:COG4886  96 TNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLS 167

                        90
                ....*....|
gi 129951   301 NNNISVVGSS 310
Cdd:COG4886 168 NNQLTDLPEE 177
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
61-193 2.99e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.39  E-value: 2.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     61 HLRVVQCSdlgLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHaliLVNNKISkVSPGAFTPlvKLERLYLSKNQ 140
Cdd:PRK15370 308 HLNVQSNS---LTALPETLPPGLKTLEAGENALTSLPASLPPELQVLD---VSKNQIT-VLPETLPP--TITTLDVSRNA 378

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 129951    141 LKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQ-----MIVIElgTNPLKSSGIEN 193
Cdd:PRK15370 379 LTNLPENLPAALQIMQASRNNLVRLPESLPHFRGEgpqptRIIVE--YNPFSERTIQN 434
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 75-305 3.02e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.16  E-value: 3.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     75 VPKDLPP--DTTLLDLQNNKIT-EIKDGdFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLK-ELPEkmpk 150
Cdd:PLN00113 348 IPKNLGKhnNLTVLDLSTNNLTgEIPEG-LCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgELPS---- 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    151 tlqelrahenEITKVRKVTFnglnqmivIELGTNPLksSGIENGAFQGMKKLSYIRIADTNITSipqGLPPS-----LTE 225
Cdd:PLN00113 423 ----------EFTKLPLVYF--------LDISNNNL--QGRINSRKWDMPSLQMLSLARNKFFG---GLPDSfgskrLEN 479

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    226 LHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT-RVPGGLAEHKYIQVVYLHNNNI 304
Cdd:PLN00113 480 LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQL 559


                 .
gi 129951    305 S 305
Cdd:PLN00113 560 S 560
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 199-286 9.02e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.01  E-value: 9.02e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   199 MKKLSYIRIADTNITSIP-QGLPPSLTELHLDGNKISRVDaaSLKGLNNLAKLGLSFNSISAVDNgsLANTPHLRELHLD 277
Cdd:cd21340   1 LKRITHLYLNDKNITKIDnLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLG 76


                ....*....
gi 129951   278 NNKLTRVPG 286
Cdd:cd21340  77 GNRISVVEG 85
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 164-305 2.86e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.08  E-value: 2.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    164 KVRKVTFnGLNQMIVIELGTNPLkSSGIENGAFQGMKKLSYIRIADTNIT-SIPQGLPPSLTELHLDGNKISRVDAASLK 242
Cdd:PLN00113  84 KISSAIF-RLPYIQTINLSNNQL-SGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIG 161

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 129951    243 GLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT-RVPGGLAEHKYIQVVYLHNNNIS 305
Cdd:PLN00113 162 SFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLS 225
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 66-259 3.09e-06

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 48.63  E-value: 3.09e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    66 QCSDLGLDKVPKDLPPDTTL--LDLQNNKITE------IKDGdfKNLKNLHALILVNNKISKVSPGAFTPLVK----LER 133
Cdd:COG5238 191 QIGDEGIEELAEALTQNTTVttLWLKRNPIGDegaeilAEAL--KGNKSLTTLDLSNNQIGDEGVIALAEALKnnttVET 268

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   134 LYLSKNQLKE-----LPE--KMPKTLQELRAHENEITKVRKVTF-NGL-NQMIVIELGtnpLKSSGIENgafQGMKKLSY 204
Cdd:COG5238 269 LYLSGNQIGAegaiaLAKalQGNTTLTSLDLSVNRIGDEGAIALaEGLqGNKTLHTLN---LAYNGIGA---QGAIALAK 342

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 129951   205 IRIADTNITSI------------------PQGlPPSLTELHLDGNKISRVDAASL-KGL--NNLAKLGLSFNSISA 259
Cdd:COG5238 343 ALQENTTLHSLdlsdnqigdegaialakyLEG-NTTLRELNLGKNNIGKQGAEALiDALqtNRLHTLILDGNLIGA 417
LRR_8 pfam13855
Leucine rich repeat;
246-304 6.83e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 6.83e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     246 NLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNI 304
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGlPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
106-157 1.04e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 1.04e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 129951     106 NLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPekmPKTLQELRA 157
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLS---PGAFSGLPS 50
LRR_8 pfam13855
Leucine rich repeat;
189-233 1.29e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.73  E-value: 1.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 129951     189 SGIENGAFQGMKKLSYIRIADTNITSIP----QGLpPSLTELHLDGNKI 233
Cdd:pfam13855  14 TSLDDGAFKGLSNLKVLDLSNNLLTTLSpgafSGL-PSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 59-313 4.51e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 38.49  E-value: 4.51e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951    59 QCHLRVVQCSDLGLDKVPKdlpPDTTLLDLQNNKITEIKDG------DFKNLKNLHALILVNNKISKVSPGAFTPLVK-- 130
Cdd:cd00116  32 GNTLGEEAAKALASALRPQ---PSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVLESLLRss 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   131 -LERLYLSKNQLKELPEKM-PKTLQELRAHeneitkvrkvtfngLNQMIvieLGTNPLKSSGIEN--GAFQGMKKLSYIR 206
Cdd:cd00116 109 sLQELKLNNNGLGDRGLRLlAKGLKDLPPA--------------LEKLV---LGRNRLEGASCEAlaKALRANRDLKELN 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951   207 IADTNITsiPQGLPpsltelHLdgnkisrvdAASLKGLNNLAKLGLSFNSISavDNGS------LANTPHLRELHLDNNK 280
Cdd:cd00116 172 LANNGIG--DAGIR------AL---------AEGLKANCNLEVLDLNNNGLT--DEGAsalaetLASLKSLEVLNLGDNN 232

                       250       260       270
                ....*....|....*....|....*....|....*....
gi 129951   281 LTRV------PGGLAEHKYIQVVYLHNNNISVVGSSDFC 313
Cdd:cd00116 233 LTDAgaaalaSALLSPNISLLTLSLSCNDITDDGAKDLA 271
LRR_8 pfam13855
Leucine rich repeat;
269-312 4.87e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.19  E-value: 4.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 129951     269 PHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 312
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGlSNLKVLDLSNNLLTTLSPGAF 45
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 86-221 5.76e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 38.68  E-value: 5.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 129951     86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLK-ELP---EKMPkTLQELRAHENE 161
Cdd:PLN00113 480 LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSgQIPasfSEMP-VLSQLDLSQNQ 558

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 129951    162 ITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSY---IRIADTNITSipqGLPP 221
Cdd:PLN00113 559 LSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVagnIDLCGGDTTS---GLPP 618
PLN03150 PLN03150
hypothetical protein; Provisional
 223-288 8.32e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 38.26  E-value: 8.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 129951    223 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT-RVPGGL 288
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSgRVPAAL 510
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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