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Conserved domains on  [gi|1125360765|gb|OLC99475|]
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dehydrogenase [Gemmatimonadetes bacterium 13_1_40CM_3_70_8]

Protein Classification

YciI family protein( domain architecture ID 10008017)

YciI family protein similar to Haemophilus influenzae YciI (HI0828) and Burkholderia phenoliruptrix 5-chlorohydroxyhydroquinone dehydrochlorinase, which is involved in the biodegradation of 2,4,5-trichlorophenoxyacetate

CATH:  3.30.70.1060

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-114 2.94e-54

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 165.34  E-value: 2.94e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125360765   1 MKYLCLIYQDEQGALKVPTAEMEKAMAEYWAFTDDIKKTGHHIASNGLQPTKTATTVRVRNGKVSTTDGPFAETKEQLGG 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSPEEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELLGG 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1125360765  81 FYLIEAKDLNDAIQVAARIPSARW-GSVEVRPVWE 114
Cdd:COG3795    81 FYLIEVEDLDEAVEWAARCPAARGgGTVEVRPVME 115
 
Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-114 2.94e-54

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 165.34  E-value: 2.94e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125360765   1 MKYLCLIYQDEQGALKVPTAEMEKAMAEYWAFTDDIKKTGHHIASNGLQPTKTATTVRVRNGKVSTTDGPFAETKEQLGG 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSPEEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELLGG 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1125360765  81 FYLIEAKDLNDAIQVAARIPSARW-GSVEVRPVWE 114
Cdd:COG3795    81 FYLIEVEDLDEAVEWAARCPAARGgGTVEVRPVME 115
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 2-114 4.35e-23

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 85.49  E-value: 4.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125360765   2 KYLCLIYqDEQGALkvptAEMEKAMAEYWAFTDDIKKTGHHIASnglqptktattvrvrnGKVSTTDGPFAETKEQLGGF 81
Cdd:pfam03795   1 LYAILAY-DKPASL----EERAALRAAHLAYLEQLKKEGVLLAS----------------GPTLVIDGPFAETKEQLGGF 59

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1125360765  82 YLIEAKDLNDAIQVAARIPSARWGSVEVRPVWE 114
Cdd:pfam03795  60 YIIEAADLDEAIAIAAGDPFVAAGLYEERPVKE 92
 
Name Accession Description Interval E-value
YCII COG3795
5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites ...
 1-114 2.94e-54

5-chloro-2-hydroxyhydroquinone dehydrochlorinase TtfG, YCII superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443009 [Multi-domain]  Cd Length: 118  Bit Score: 165.34  E-value: 2.94e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125360765   1 MKYLCLIYQDEQGALKVPTAEMEKAMAEYWAFTDDIKKTGHHIASNGLQPTKTATTVRVRNGKVSTTDGPFAETKEQLGG 80
Cdd:COG3795     1 MKYLLLIYADEEAEAGLSPEEMEALMAAMGAFNEELAAAGVLVAGEGLQPPSTATTVRVRDGKPVVTDGPFAETKELLGG 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1125360765  81 FYLIEAKDLNDAIQVAARIPSARW-GSVEVRPVWE 114
Cdd:COG3795    81 FYLIEVEDLDEAVEWAARCPAARGgGTVEVRPVME 115
YCII pfam03795
YCII-related domain; The majority of proteins in this family consist of a single copy of this ...
 2-114 4.35e-23

YCII-related domain; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in Swiss:Q9A8M4. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.


Pssm-ID: 397734  Cd Length: 94  Bit Score: 85.49  E-value: 4.35e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1125360765   2 KYLCLIYqDEQGALkvptAEMEKAMAEYWAFTDDIKKTGHHIASnglqptktattvrvrnGKVSTTDGPFAETKEQLGGF 81
Cdd:pfam03795   1 LYAILAY-DKPASL----EERAALRAAHLAYLEQLKKEGVLLAS----------------GPTLVIDGPFAETKEQLGGF 59

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1125360765  82 YLIEAKDLNDAIQVAARIPSARWGSVEVRPVWE 114
Cdd:pfam03795  60 YIIEAADLDEAIAIAAGDPFVAAGLYEERPVKE 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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