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Conserved domains on  [gi|1084678830|gb|OGP26246|]
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glycerol-3-phosphate dehydrogenase [Deltaproteobacteria bacterium GWB2_65_81]

Protein Classification

similar to glycerol-3-phosphate dehydrogenase( domain architecture ID 11415519)

protein similar to glycerol-3-phosphate dehydrogenase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 1-311 1.98e-161

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


:

Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 452.95  E-value: 1.98e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:COG0240    18 VLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQALREVLEQLAPLLPPG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHaLRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:COG0240    98 APVVSATKGIEPGTGLLMSEVIAEELPGA-LRIAVLSGPSFAEEVARGLPTAVVVASEDEEVAERLQELLSTPYFRVYTS 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:COG0240   177 DDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAGLGDLVLTCTSDLSRNRR 256

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSRALK 311
Cdd:COG0240   257 FGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVEALMARPLK 327
 
Name Accession Description Interval E-value
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 1-311 1.98e-161

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 452.95  E-value: 1.98e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:COG0240    18 VLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQALREVLEQLAPLLPPG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHaLRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:COG0240    98 APVVSATKGIEPGTGLLMSEVIAEELPGA-LRIAVLSGPSFAEEVARGLPTAVVVASEDEEVAERLQELLSTPYFRVYTS 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:COG0240   177 DDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAGLGDLVLTCTSDLSRNRR 256

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSRALK 311
Cdd:COG0240   257 FGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVEALMARPLK 327
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
1-308 8.15e-158

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 443.36  E-value: 8.15e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:PRK00094   19 VLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQALREVLKQLKPLLPPD 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHAlRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:PRK00094   99 APIVWATKGIEPGTGKLLSEVLEEELPDLA-PIAVLSGPSFAKEVARGLPTAVVIASTDEELAERVQELFHSPYFRVYTN 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:PRK00094  178 TDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAGLGDLVLTCTSPLSRNRR 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSR 308
Cdd:PRK00094  258 FGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVEDLMGR 325
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 162-303 2.36e-75

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 227.27  E-value: 2.36e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 162 DVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRTV 241
Cdd:pfam07479   1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALGAKPETFFGLAGLGDLIVTCTSGLSRNRRF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1084678830 242 GMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVD 303
Cdd:pfam07479  81 GEALGKGKSLEEAEKELGQVAEGVYTAKAVYELAKKLGVEMPIFEAVYRILYEGKSPEEALE 142
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 6-298 6.38e-57

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 187.16  E-value: 6.38e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   6 HDPVALWAFEPSVCAD-----IRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:TIGR03376  30 EESVRMWVFEEEIEGRnlteiINTTHENVKYLPGIKLPANLVAVPDLVEAAKGADILVFVIPHQFLEGICKQLKGHVKPN 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGslKRMTELLAEAAPEH-ALRVAALSGPTFAREVAEGKPTGATVAADDLAV----ARRLQHALAGPRF 155
Cdd:TIGR03376 110 ARAISCIKGLEVS--KDGVKLLSDIIEEElGIPCGVLSGANLANEVAKEKFSETTVGYRDPADfdvdARVLKALFHRPYF 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 156 RLYADDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLG--AHPQTFAGLSGMGDLVLTCTG 233
Cdd:TIGR03376 188 RVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFARMFFptGEVTFTFESCGVADLITTCLG 267

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 234 dlSRNRTVGMRLGR-GERIGDVLAGMT--MVAEGVRTAVSAVELSRRTGV--PMPISEQVHGILHEGKDV 298
Cdd:TIGR03376 268 --GRNFKVGRAFAKtGKSLEELEKELLngQSLQGVATAKEVHELLKNKNKddEFPLFEAVYQILYEGLPP 335
 
Name Accession Description Interval E-value
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 1-311 1.98e-161

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 452.95  E-value: 1.98e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:COG0240    18 VLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQALREVLEQLAPLLPPG 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHaLRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:COG0240    98 APVVSATKGIEPGTGLLMSEVIAEELPGA-LRIAVLSGPSFAEEVARGLPTAVVVASEDEEVAERLQELLSTPYFRVYTS 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:COG0240   177 DDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAGLGDLVLTCTSDLSRNRR 256

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSRALK 311
Cdd:COG0240   257 FGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVEALMARPLK 327
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
1-308 8.15e-158

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 443.36  E-value: 8.15e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:PRK00094   19 VLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQALREVLKQLKPLLPPD 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHAlRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:PRK00094   99 APIVWATKGIEPGTGKLLSEVLEEELPDLA-PIAVLSGPSFAKEVARGLPTAVVIASTDEELAERVQELFHSPYFRVYTN 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:PRK00094  178 TDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAGLGDLVLTCTSPLSRNRR 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSR 308
Cdd:PRK00094  258 FGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVEDLMGR 325
PRK12439 PRK12439
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 2-301 1.50e-98

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 171500 [Multi-domain]  Cd Length: 341  Bit Score: 294.00  E-value: 1.50e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   2 LAGAHDPVALWAFEPSVCADIRDRRENRAFLP-GIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:PRK12439   25 ICARRGPTLQWVRSAETADDINDNHRNSRYLGnDVVLSDTLRATTDFAEAANCADVVVMGVPSHGFRGVLTELAKELRPW 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGSLKRMTELLAEAAPEHAlrVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYAD 160
Cdd:PRK12439  105 VPVVSLVKGLEQGTNMRMSQIIEEVLPGHP--AGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSPLFRTRRFRVYTT 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 161 DDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRT 240
Cdd:PRK12439  183 DDVVGVEMAGALKNVFAIAVGMGYSLGIGENTRAMVIARALREMTKLGVAMGGNPETFAGLAGMGDLIVTCTSQRSRNRH 262

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084678830 241 VGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQA 301
Cdd:PRK12439  263 VGEQLGAGKPIDEIIASMNQVAEGVKAASVVMEFADEYGLNMPIAREVDAVINHGSTVEQA 323
PRK14619 PRK14619
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 42-313 3.29e-76

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237771 [Multi-domain]  Cd Length: 308  Bit Score: 235.65  E-value: 3.29e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  42 RPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAA-HLSPGACLVSLAKGVENGSLKRMTELLAEAAPEHALRVaaLSGPT 120
Cdd:PRK14619   36 RSGLSLAAVLADADVIVSAVSMKGVRPVAEQVQAlNLPPETIIVTATKGLDPETTRTPSQIWQAAFPNHPVVV--LSGPN 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 121 FAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYADDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRG 200
Cdd:PRK14619  114 LSKEIQQGLPAATVVASRDLAAAETVQQIFSSERFRVYTNSDPLGTELGGTLKNVIAIAAGVCDGLQLGTNAKAALVTRA 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 201 LAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRTVGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGV 280
Cdd:PRK14619  194 LPEMIRVGTHLGAQTETFYGLSGLGDLLATCTSPLSRNYQVGYGLAQGKSLEQILAELEGTAEGVNTANVLVQLAQQQNI 273

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1084678830 281 PMPISEQVHGILHEGKDVRQAVDELFSRALKRE 313
Cdd:PRK14619  274 AVPITEQVYRLLQGEITPQQALEELMERDLKPE 306
NAD_Gly3P_dh_C pfam07479
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ...
 162-303 2.36e-75

NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.


Pssm-ID: 462178 [Multi-domain]  Cd Length: 142  Bit Score: 227.27  E-value: 2.36e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 162 DVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRNRTV 241
Cdd:pfam07479   1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALGAKPETFFGLAGLGDLIVTCTSGLSRNRRF 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1084678830 242 GMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVD 303
Cdd:pfam07479  81 GEALGKGKSLEEAEKELGQVAEGVYTAKAVYELAKKLGVEMPIFEAVYRILYEGKSPEEALE 142
PRK14618 PRK14618
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 1-313 1.30e-72

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237770 [Multi-domain]  Cd Length: 328  Bit Score: 227.06  E-value: 1.30e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRgvaaRAAAHLSPG 80
Cdd:PRK14618   22 LAASKGVPVRLWARRPEFAAALAAERENREYLPGVALPAELYPTADPEEALAGADFAVVAVPSKALR----ETLAGLPRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGV--ENGSLKRMTELLAEAAPEhalRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLY 158
Cdd:PRK14618   98 LGYVSCAKGLapDGGRLSELARVLEFLTQA---RVAVLSGPNHAEEIARFLPAATVVASPEPGLARRVQAAFSGPSFRVY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 159 ADDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLGAHPQTFAGLSGMGDLVLTCTGDLSRN 238
Cdd:PRK14618  175 TSRDRVGVELGGALKNVIALAAGMVDGLKLGDNAKAALITRGLREMVRFGVALGAEEATFYGLSGLGDLIATATSPHSRN 254

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1084678830 239 RTVGMRLGRGERIGDVLAGMTMVaEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFSRALKRE 313
Cdd:PRK14618  255 RAAGEAIVRGVDREHLEAGGKVV-EGLYTVKALDAWAKAHGHDLPIVEAVARVARGGWDPLAGLRSLMGREAKEE 328
glycerol3P_DH TIGR03376
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ...
 6-298 6.38e-57

glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.


Pssm-ID: 274551 [Multi-domain]  Cd Length: 342  Bit Score: 187.16  E-value: 6.38e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   6 HDPVALWAFEPSVCAD-----IRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:TIGR03376  30 EESVRMWVFEEEIEGRnlteiINTTHENVKYLPGIKLPANLVAVPDLVEAAKGADILVFVIPHQFLEGICKQLKGHVKPN 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  81 ACLVSLAKGVENGslKRMTELLAEAAPEH-ALRVAALSGPTFAREVAEGKPTGATVAADDLAV----ARRLQHALAGPRF 155
Cdd:TIGR03376 110 ARAISCIKGLEVS--KDGVKLLSDIIEEElGIPCGVLSGANLANEVAKEKFSETTVGYRDPADfdvdARVLKALFHRPYF 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 156 RLYADDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRLG--AHPQTFAGLSGMGDLVLTCTG 233
Cdd:TIGR03376 188 RVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGLLEMIKFARMFFptGEVTFTFESCGVADLITTCLG 267

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 234 dlSRNRTVGMRLGR-GERIGDVLAGMT--MVAEGVRTAVSAVELSRRTGV--PMPISEQVHGILHEGKDV 298
Cdd:TIGR03376 268 --GRNFKVGRAFAKtGKSLEELEKELLngQSLQGVATAKEVHELLKNKNKddEFPLFEAVYQILYEGLPP 335
PRK14620 PRK14620
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 2-307 3.78e-54

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 173083 [Multi-domain]  Cd Length: 326  Bit Score: 179.64  E-value: 3.78e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   2 LAGAHDPVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGR-TVVAFAVPSHHLRGVAARAA-AHLSP 79
Cdd:PRK14620   19 LSSKKISVNLWGRNHTTFESINTKRKNLKYLPTCHLPDNISVKSAIDEVLSDNaTCIILAVPTQQLRTICQQLQdCHLKK 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  80 GACLVSLAKGVENGSLKRMTELLAEAAPEHAlrVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFRLYA 159
Cdd:PRK14620   99 NTPILICSKGIEKSSLKFPSEIVNEILPNNP--IAILSGPSFAKEIAEKLPCSIVLAGQNETLGSSLISKLSNENLKIIY 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 160 DDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRL------GVRLgahpQTFAGLSGMGDLVLTCTG 233
Cdd:PRK14620  177 SQDIIGVQIGAALKNIIAIACGIVLGKNLGNNAHAAVITKGMNEIKTLysakngSIDL----NTLIGPSCLGDLILTCTT 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1084678830 234 DLSRNRTVGMRLGRGERIGDVLAGMTMVAEGVRTAVSAVELSRRTGVPMPISEQVHGILHEGKDVRQAVDELFS 307
Cdd:PRK14620  253 LHSRNMSFGFKIGNGFNINQILSEGKSVIEGFSTVKPLISLAKKLNIELPICESIYNLLYENISLEKTISVILS 326
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 8-143 4.70e-47

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 155.81  E-value: 4.70e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   8 PVALWAFEPSVCADIRDRRENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPGACLVSLA 87
Cdd:pfam01210  24 EVRLWGRDEELIEEINTTHENVRYLPGIKLPENLKATTDLAEALKGADIIVIVVPSQALREVLKQLKGLLKPDAILVSLS 103

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1084678830  88 KGVENGSLKRMTELLAEAAPEHAlRVAALSGPTFAREVAEGKPTGATVAADDLAVA 143
Cdd:pfam01210 104 KGIEPGTLKLLSEVIEEELGIQP-PIAVLSGPSHAEEVAQGLPTATVIASKDEEAA 158
PTZ00345 PTZ00345
glycerol-3-phosphate dehydrogenase; Provisional
 6-239 2.39e-34

glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 240373 [Multi-domain]  Cd Length: 365  Bit Score: 128.60  E-value: 2.39e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   6 HDPVALWAFEPSV----CADIRDRR-ENRAFLPGIVLPEGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAA--RAAAHLS 78
Cdd:PTZ00345   41 HNEVRMWVLEEIVegekLSDIINTKhENVKYLPGIKLPDNIVAVSDLKEAVEDADLLIFVIPHQFLESVLSqiKENNNLK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  79 PGACLVSLAKG--VENGSLKRMTELLAEaapEHALRVAALSGPTFAREVAEGKPTGATVAADDLAVARRLQHALAGPRFR 156
Cdd:PTZ00345  121 KHARAISLTKGiiVENGKPVLCSDVIEE---ELGIPCCALSGANVANDVAREEFSEATIGCEDKDDALIWQRLFDRPYFK 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830 157 LYADDDVTGIEIGGALKNVMAIAAGMADGLGFGHNARALLISRGLAEITRLGVRL--GAHPQTFAGLSGMGDLVLTCTGd 234
Cdd:PTZ00345  198 INCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRIGLEEMKLFGKIFfpNVMDETFFESCGLADLITTCLG- 276


                  ....*
gi 1084678830 235 lSRNR 239
Cdd:PTZ00345  277 -GRNV 280
GPD_NAD_C_bact pfam20618
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent ...
 222-288 9.21e-24

Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent glycerol-3-phosphate dehydrogenase (GPD) from bacteria and archaea. GPD catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate.


Pssm-ID: 466767 [Multi-domain]  Cd Length: 66  Bit Score: 92.17  E-value: 9.21e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1084678830 222 SGMGDLVLTCTGDLSRNRTVGMRLGRGERIgdVLAGMTMVAEGVRTA-VSAVELSRRTGVPMPISEQV 288
Cdd:pfam20618   1 AGLGDLVLTCTSDLSRNRTFGLLLGKGMTL--AEAGNGQVAEGVRTAkAVAAILARAHNVEMPILEAV 66
ProC COG0345
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ...
 1-107 8.77e-06

Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis


Pssm-ID: 440114 [Multi-domain]  Cd Length: 267  Bit Score: 46.21  E-value: 8.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830   1 MLAGAHDPVALWAFEPSvcADIRDRRENRAflpgivlpeGVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPG 80
Cdd:COG0345    21 LLKSGVPPEDIIVSDRS--PERLEALAERY---------GVRVTTDNAEAAAQADVVVLAVKPQDLAEVLEELAPLLDPD 89

                          90       100
                  ....*....|....*....|....*..
gi 1084678830  81 ACLVSLAKGVengSLKRMTELLAEAAP 107
Cdd:COG0345    90 KLVISIAAGV---TLATLEEALGGGAP 113
PLN02688 PLN02688
pyrroline-5-carboxylate reductase
 40-185 5.75e-05

pyrroline-5-carboxylate reductase


Pssm-ID: 178291 [Multi-domain]  Cd Length: 266  Bit Score: 43.79  E-value: 5.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084678830  40 GVRPTNDLAEAVSGRTVVAFAVPSHHLRGVAARAAAHLSPGACLVSLAKGVengSLKRMTEllaEAAPEHALRVAAlSGP 119
Cdd:PLN02688   48 GVKTAASNTEVVKSSDVIILAVKPQVVKDVLTELRPLLSKDKLLVSVAAGI---TLADLQE---WAGGRRVVRVMP-NTP 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1084678830 120 TFAREVAEGKPTGATVAADDLAVARRLQHALAgprfRLYADDD-----VTGIEIGGALKNVMAIAAgMADG 185
Cdd:PLN02688  121 CLVGEAASVMSLGPAATADDRDLVATLFGAVG----KIWVVDEklldaVTGLSGSGPAYIFLAIEA-LADG 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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