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Conserved domains on  [gi|1081394524|gb|OFV31049|]
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choline transporter [Staphylococcus sp. HMSC14D10]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKFSSVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKL 80
Cdd:COG1292     1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  81 KLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292    81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 160 ALAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIG 239
Cdd:COG1292   161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNGqkREWMSS 319
Cdd:COG1292   241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVLGIETGKKHP----ELFKMTPETQLFG 395
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 396 VFHHVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLEPSRAVKVTWGVSQSLIAFILLLAGGgngadaLNAIQ 475
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                         490       500       510
                  ....*....|....*....|....*....|
gi 1081394524 476 SAAIISAFPFSFVVIMMMISFYKDANQERK 505
Cdd:COG1292   473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKFSSVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKL 80
Cdd:COG1292     1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  81 KLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292    81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 160 ALAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIG 239
Cdd:COG1292   161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNGqkREWMSS 319
Cdd:COG1292   241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVLGIETGKKHP----ELFKMTPETQLFG 395
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 396 VFHHVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLEPSRAVKVTWGVSQSLIAFILLLAGGgngadaLNAIQ 475
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                         490       500       510
                  ....*....|....*....|....*....|
gi 1081394524 476 SAAIISAFPFSFVVIMMMISFYKDANQERK 505
Cdd:COG1292   473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 616.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  17 VFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKLKLGKPNDKPEFNTVSW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  97 FAMLFSAGMGIGLVFYGAAEPMAHFAS-PPNADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYAQFRKNEPGLIS 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 176 RTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIGVVTILFIASAWSGLSK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 256 GIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALnGQKREWMSSWTLYYWGWWLSWSPFV 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 336 GVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVLGIETGKKHP----ELFKMTPETQLFGVFHHVPLGMALSLIAL 411
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 412 VLIASFFITSADSATFVLGMQTTFGSLEPSRAVKVTWGVSQSLIAFILLLAGGgngadaLNAIQSAAIISAFPFSFVVIM 491
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 1081394524 492 MMISFYKDANQE 503
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 9.97e-166

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 478.00  E-value: 9.97e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  55 GWYYLILTTVIVFFCIFLIFSPIGKLKLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTE 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPfGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 134 AYTEALRSTFFHWGFHAWAVYGVVALALAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 214 ALQINGGLHYLFGVPNNVWVQSIIIGVVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 294 SLLNTFLFNSFDTAALNGqKREWMSSWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVL 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDG-KGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 374 GIETGKKH-----PELFKMTPETQLFGVFHHVPLGMALSLIALVLIASFFITSADSATFVLG-MQTTFGSL--EPSRAVK 445
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLgeEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1081394524 446 VTWGVSQSLIAFILLLAGGgngadALNAIQSAAIISAFPFSFVVIMMMISFYKDANQE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-498 1.08e-126

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 385.97  E-value: 1.08e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKFSSVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKL 80
Cdd:PRK09928    3 MTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  81 KLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPPNADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALA 160
Cdd:PRK09928   83 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 161 LAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIGV 240
Cdd:PRK09928  163 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIAL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 241 VTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNgQKREWMSSW 320
Cdd:PRK09928  243 SVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFD-RPTEWMNNW 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 321 TLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFG----VLGIETGKKHPELFKMTPETQLFGV 396
Cdd:PRK09928  322 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGnsalYEIIHGNAAFAEEAMAHPERGFYSL 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 397 FHHVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLEPSRA---VKVTWGVSQSLIAFILLLAGGgngadaLNA 473
Cdd:PRK09928  402 LAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDApnwLRVFWSVAIGLLTLGMLMTNG------ISA 475
                         490       500
                  ....*....|....*....|....*
gi 1081394524 474 IQSAAIISAFPFSFVVIMMMISFYK 498
Cdd:PRK09928  476 LQNTTVIMGLPFSFVIFFVMAGLYK 500
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKFSSVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKL 80
Cdd:COG1292     1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  81 KLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292    81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 160 ALAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIG 239
Cdd:COG1292   161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNGqkREWMSS 319
Cdd:COG1292   241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVLGIETGKKHP----ELFKMTPETQLFG 395
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGgdlaEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 396 VFHHVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLEPSRAVKVTWGVSQSLIAFILLLAGGgngadaLNAIQ 475
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                         490       500       510
                  ....*....|....*....|....*....|
gi 1081394524 476 SAAIISAFPFSFVVIMMMISFYKDANQERK 505
Cdd:COG1292   473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 616.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  17 VFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKLKLGKPNDKPEFNTVSW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  97 FAMLFSAGMGIGLVFYGAAEPMAHFAS-PPNADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYAQFRKNEPGLIS 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 176 RTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIGVVTILFIASAWSGLSK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 256 GIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALnGQKREWMSSWTLYYWGWWLSWSPFV 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 336 GVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVLGIETGKKHP----ELFKMTPETQLFGVFHHVPLGMALSLIAL 411
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 412 VLIASFFITSADSATFVLGMQTTFGSLEPSRAVKVTWGVSQSLIAFILLLAGGgngadaLNAIQSAAIISAFPFSFVVIM 491
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 1081394524 492 MMISFYKDANQE 503
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 9.97e-166

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 478.00  E-value: 9.97e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  55 GWYYLILTTVIVFFCIFLIFSPIGKLKLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTE 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPfGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 134 AYTEALRSTFFHWGFHAWAVYGVVALALAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 214 ALQINGGLHYLFGVPNNVWVQSIIIGVVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 294 SLLNTFLFNSFDTAALNGqKREWMSSWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFGVL 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDG-KGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 374 GIETGKKH-----PELFKMTPETQLFGVFHHVPLGMALSLIALVLIASFFITSADSATFVLG-MQTTFGSL--EPSRAVK 445
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLgeEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1081394524 446 VTWGVSQSLIAFILLLAGGgngadALNAIQSAAIISAFPFSFVVIMMMISFYKDANQE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-498 1.08e-126

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 385.97  E-value: 1.08e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKFSSVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKL 80
Cdd:PRK09928    3 MTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  81 KLGKPNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPPNADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALA 160
Cdd:PRK09928   83 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 161 LAYAQFRKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIGV 240
Cdd:PRK09928  163 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIAL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 241 VTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNgQKREWMSSW 320
Cdd:PRK09928  243 SVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFD-RPTEWMNNW 321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 321 TLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFLWFSVFG----VLGIETGKKHPELFKMTPETQLFGV 396
Cdd:PRK09928  322 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGnsalYEIIHGNAAFAEEAMAHPERGFYSL 401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 397 FHHVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLEPSRA---VKVTWGVSQSLIAFILLLAGGgngadaLNA 473
Cdd:PRK09928  402 LAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDApnwLRVFWSVAIGLLTLGMLMTNG------ISA 475
                         490       500
                  ....*....|....*....|....*
gi 1081394524 474 IQSAAIISAFPFSFVVIMMMISFYK 498
Cdd:PRK09928  476 LQNTTVIMGLPFSFVIFFVMAGLYK 500
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
1-500 3.23e-72

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 238.87  E-value: 3.23e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524   1 MNSSSEETKQNKKfssVFIYSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGW---YYLILTTVIVFFcifLIFSPI 77
Cdd:PRK03356    1 MKNEKKKTGIEPK---VFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWafeWYMVVMLFGWFW---LVFGPY 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  78 GKLKLGkpNDKPEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTEAYTEALRSTFFHWGFHAWAVYGV 156
Cdd:PRK03356   75 AKKRLG--DEKPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPfGLEPNSTGAKELGLAYSLFHWGPLPWATYSF 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 157 VALALAYAQF-RKNEPGLISRTLRPILGDK-VEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQ 234
Cdd:PRK03356  153 LSVAFGYFFFvRKMDVIRPSSTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLD 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 235 SIIIGVVTILFIASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNgqKR 314
Cdd:PRK03356  233 AIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIG--KG 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 315 EWMSSWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLvpAIVSFLWFsVFGVLGIETGKKHPE-LFKMTPETQL 393
Cdd:PRK03356  311 GFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVL--GLTASTWI-LWTVLGSNTLLLMDKnIINIPNLIEQ 387
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 394 FGVFHHVPLGMALSLIALVLIASFFI-------TSADSATFVLGMQTTFGSL---EPSRAVKVTWGVSQSLIAFILLLAG 463
Cdd:PRK03356  388 YGVARAIIETWAALPLSTATMWGFFIlcfiatvTLINACSYTLAMSTCREVRdgeEPPLLVRIGWSILVGIIGIVLLALG 467
                         490       500       510
                  ....*....|....*....|....*....|....*..
gi 1081394524 464 GgngadaLNAIQSAAIISAFPFSFVVIMMMISFYKDA 500
Cdd:PRK03356  468 G------LKPIQTAIIAGGCPLFFVNIMVTLSFIKDA 498
PRK09950 PRK09950
putative transporter; Provisional
11-503 1.20e-70

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 235.07  E-value: 1.20e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  11 NKKFSSVFI--YSAIVVAIVVLIGAFLPEQFGKITGDISSWITEKLGWYYLILTTVIVFFCIFLIFSPIGKLKLGKpnDK 88
Cdd:PRK09950    4 NKKKKDKPLisTSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGE--GK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524  89 PEFNTVSWFAMLFSAGMGIGLVFYGAAEPMAHFASPP-NADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYA-QF 166
Cdd:PRK09950   82 PEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGlNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYHfHV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 167 RKNEPGLISRTLRPILGDKVEGPIGTIIDVLSVFATVVGVAVSLGMGALQINGGLHYLFGVPNNVWVQSIIIGVVTILFI 246
Cdd:PRK09950  162 RKNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFC 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 247 ASAWSGLSKGIQYLSNLNIGLGTVLMIIALIIGPTVLILNMFTSSTGSLLNTFLFNSFDTAALNGQKreWMSSWTLYYWG 326
Cdd:PRK09950  242 LSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGDGS--FTRNWTVFYWL 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 327 WWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIvsFLWFsVFGVLG-------IETGKKHPELFK-MTPETQLFGVFH 398
Cdd:PRK09950  320 WWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSSV--GCWF-FFGVLEsyaihqfINGVINVPQILNtLGGETAVQQLLS 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1081394524 399 HVPLGMALSLIALVLIASFFITSADSATFVLGMQTTFGSLE---PSRAVKVTWGVSQSLIAFILLLAGGgngadALNAIQ 475
Cdd:PRK09950  397 SLPAGKLFLAAYLGIMIIFLASHMDAVAYTMAATSTRNLREgddPDRGLRLFWCVVITLIPLSILFTGA-----SLDTMK 471
                         490       500
                  ....*....|....*....|....*...
gi 1081394524 476 SAAIISAFPFSFVVIMMMISFYKDANQE 503
Cdd:PRK09950  472 TTVVLTALPFLVILLIKVYGFIRWLKQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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