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Conserved domains on  [gi|1080201616|gb|OFJ97767|]
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transposase, partial [Lactobacillus sp. HMSC066G01]

Protein Classification

transposase family protein( domain architecture ID 1750073)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  21439812

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS5_3 super family cl41332
IS5 family transposase;
1-100 9.06e-25

IS5 family transposase;


The actual alignment was detected with superfamily member NF033580:

Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 93.41  E-value: 9.06e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080201616   1 NVSDRSGALAMLS-LASQNLELVQHVMVDGGYTGnDFADQVKLILNAKTT-VAKRNEL---HMFTVLPQRWIVERSWSWL 75
Cdd:NF033580  149 NVHDSKGALPLLDgLPVLRPPRPKHLLADKGYDS-DALRAALRERGAVPViPRRRNRLrpaYDFRLYKKRWVVERTFAWL 227

                          90       100
                  ....*....|....*....|....*
gi 1080201616  76 DKCRRLWKNCERALNSSLQMVVLAF 100
Cdd:NF033580  228 KRFRRLATRYEKLARNFLAFVHLAC 252
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
1-100 9.06e-25

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 93.41  E-value: 9.06e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080201616   1 NVSDRSGALAMLS-LASQNLELVQHVMVDGGYTGnDFADQVKLILNAKTT-VAKRNEL---HMFTVLPQRWIVERSWSWL 75
Cdd:NF033580  149 NVHDSKGALPLLDgLPVLRPPRPKHLLADKGYDS-DALRAALRERGAVPViPRRRNRLrpaYDFRLYKKRWVVERTFAWL 227

                          90       100
                  ....*....|....*....|....*
gi 1080201616  76 DKCRRLWKNCERALNSSLQMVVLAF 100
Cdd:NF033580  228 KRFRRLATRYEKLARNFLAFVHLAC 252
DDE_Tnp_1_2 pfam13586
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 59-100 1.14e-06

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 463928 [Multi-domain]  Cd Length: 90  Bit Score: 42.79  E-value: 1.14e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1080201616  59 FTVLPQRWIVERSWSWLDKCRRLWKNCERALNSSLQMVVLAF 100
Cdd:pfam13586  43 REDEIARNVIEGKFGWFKRRRSLAKRYEKLASTFEGAIALTF 84
 
Name Accession Description Interval E-value
transpos_IS5_3 NF033580
IS5 family transposase;
1-100 9.06e-25

IS5 family transposase;


Pssm-ID: 468097 [Multi-domain]  Cd Length: 257  Bit Score: 93.41  E-value: 9.06e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080201616   1 NVSDRSGALAMLS-LASQNLELVQHVMVDGGYTGnDFADQVKLILNAKTT-VAKRNEL---HMFTVLPQRWIVERSWSWL 75
Cdd:NF033580  149 NVHDSKGALPLLDgLPVLRPPRPKHLLADKGYDS-DALRAALRERGAVPViPRRRNRLrpaYDFRLYKKRWVVERTFAWL 227

                          90       100
                  ....*....|....*....|....*
gi 1080201616  76 DKCRRLWKNCERALNSSLQMVVLAF 100
Cdd:NF033580  228 KRFRRLATRYEKLARNFLAFVHLAC 252
DDE_Tnp_1_2 pfam13586
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 59-100 1.14e-06

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 463928 [Multi-domain]  Cd Length: 90  Bit Score: 42.79  E-value: 1.14e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1080201616  59 FTVLPQRWIVERSWSWLDKCRRLWKNCERALNSSLQMVVLAF 100
Cdd:pfam13586  43 REDEIARNVIEGKFGWFKRRRSLAKRYEKLASTFEGAIALTF 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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