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Conserved domains on  [gi|47086189|ref|NP_998090|]
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propionyl-CoA carboxylase beta chain, mitochondrial [Danio rerio]

Protein Classification

acyl-CoA carboxylase subunit beta( domain architecture ID 11469175)

acyl-CoA carboxylase subunit beta, such as propionyl-CoA carboxylase subunit beta, which is the catalytic carboxyltransferase subunit of the enzyme that catalyzes the carboxylation of propionyl-CoA to form methylmalonyl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016874|GO:0006633|GO:0009317|GO:0003989
PubMed:  8102604
SCOP:  4000456

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
53-546 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


:

Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 810.02  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  53 ERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDfgmeaDQNKYPGDSVVTGQGRING 132
Cdd:COG4799   7 AELRARREEALLGGGEKAIERQHARGKLTARERIDLLLDPGSFLELGALAGHRMYD-----DDDRVPGDGVVTGIGTVDG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 133 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLI 212
Cdd:COG4799  82 RPVVVVANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 213 MGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFN 292
Cdd:COG4799 162 MGPCAAGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLS 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 293 FLPLSNKDSAPVVECHDPrDRLVPGLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVG 372
Cdd:COG4799 242 YLPSNNLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVA 320

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 373 NQPKVASGCLDINSSVKGARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYG 452
Cdd:COG4799 321 NQPMVLAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYG 400

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 453 GAYDVMSSKHLRGDVNYAWPTAEVAVMGAKGAVQIIFRGKQNQAEAEAEYV-------EKFANPFPAAVRGFVDDIIQPS 525
Cdd:COG4799 401 AGYYAMCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRRELAAAEDPEALRaeliaeyEEQANPYYAAARGWIDDVIDPR 480

                       490       500
                ....*....|....*....|.
gi 47086189 526 TTRRRICRDLEVLASKKQTNP 546
Cdd:COG4799 481 DTRRVLARALEAAANKPEERP 501
 
Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
53-546 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 810.02  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  53 ERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDfgmeaDQNKYPGDSVVTGQGRING 132
Cdd:COG4799   7 AELRARREEALLGGGEKAIERQHARGKLTARERIDLLLDPGSFLELGALAGHRMYD-----DDDRVPGDGVVTGIGTVDG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 133 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLI 212
Cdd:COG4799  82 RPVVVVANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 213 MGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFN 292
Cdd:COG4799 162 MGPCAAGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLS 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 293 FLPLSNKDSAPVVECHDPrDRLVPGLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVG 372
Cdd:COG4799 242 YLPSNNLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVA 320

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 373 NQPKVASGCLDINSSVKGARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYG 452
Cdd:COG4799 321 NQPMVLAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYG 400

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 453 GAYDVMSSKHLRGDVNYAWPTAEVAVMGAKGAVQIIFRGKQNQAEAEAEYV-------EKFANPFPAAVRGFVDDIIQPS 525
Cdd:COG4799 401 AGYYAMCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRRELAAAEDPEALRaeliaeyEEQANPYYAAARGWIDDVIDPR 480

                       490       500
                ....*....|....*....|.
gi 47086189 526 TTRRRICRDLEVLASKKQTNP 546
Cdd:COG4799 481 DTRRVLARALEAAANKPEERP 501
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 73-547 0e+00

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 702.09  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189    73 AQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDFGMEadqnKYPGDSVVTGQGRINGRLVYVFSQDFTVFGGSLSGA 152
Cdd:pfam01039   1 PEHPRGKLTARERIDLLLDPGSFGELEDLFFHRATEFGRK----RIPRDGVVTGSGAVIGRAVEVVAQDFTVFGGSLGPA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   153 HAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLIMGPCAGGAVYSPALTDFTFM 232
Cdd:pfam01039  77 KGEKILRAMEIAIKTGLPLIGINDSGGARIQEGVENLRGSGKIFGRNSLASGVIPQISLIMGPCAGGGAYLPALGDFVIM 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   233 VKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFNFLPL---SNKDSAPVVECHD 309
Cdd:pfam01039 157 VEGTSPMFLTGPPVIKKVTGEEVTSEELGGATQHMTISGVSHLTALDDEDALELIRKWLSYLPKpapNNREPVPIVPTKD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   310 PRDRLVPgLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVGNQPKVASGCLDINSSVK 389
Cdd:pfam01039 237 PPDRDAP-LVSIVPDDPKKPYDVREVIAGIVDEGEFFEIKPGYAKTVVTGFARLGGIPVGVVANQPRVGAGVLFPDSADK 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   390 GARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLRGDVNY 469
Cdd:pfam01039 316 AARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKHGAKLLYALAEATVPKITVIPRKAYGGAYVVMDSKINGADINF 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   470 AWPTAEVAVMGAKGAVQIIFRGKQNQAEAE------------AEYVEKFANPFPAAVRGFVDDIIQPSTTRRRICRDLEV 537
Cdd:pfam01039 396 AWPTARIAVMGPEGAVEIKFRKEKAAAEMRgkdlaatrkqkiAEYEEELSPPYVAAARGFADAVIDPGRTRAKLVIALAA 475

                         490
                  ....*....|
gi 47086189   538 LASKKQTNPC 547
Cdd:pfam01039 476 LWTKPRFFPW 485
mmdA TIGR01117
methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA ...
 53-546 0e+00

methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130187  Cd Length: 512  Bit Score: 688.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189    53 ERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDFGMeaDQNKYPGDSVVTGQGRING 132
Cdd:TIGR01117   4 EELHEKKEKIKQGGGEKRIEKQHAQGKMTARERLALLFDPGSFVEIDQFVKHRCTNFGM--DKKELPAEGVVTGYGTIDG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   133 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLI 212
Cdd:TIGR01117  82 RLVYAFAQDFTVMGGSLGEMHAAKIVKIMDLAMKMGAPVVGLNDSGGARIQEAVDALKGYGDIFYRNTIASGVVPQISAI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   213 MGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFN 292
Cdd:TIGR01117 162 MGPCAGGAVYSPALTDFIYMVDNTSQMFITGPQVIKTVTGEEVTAEQLGGAMAHNSVSGVAHFIAEDDDDCIMLIRRLLS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   293 FLPLSNKDSAPVVECHDPRDRLVPGLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVG 372
Cdd:TIGR01117 242 FLPSNNMEKAPLVKTGDDPTRETPELYDLLPDNPNKPYDMRDVITAIVDNGDYLEVQPYYAPNIITCFARINGQSVGIIA 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   373 NQPKVASGCLDINSSVKGARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYG 452
Cdd:TIGR01117 322 NQPKVMAGCLDIDSSDKIARFIRFCDAFNIPIVTFVDVPGFLPGVNQEYGGIIRHGAKVLYAYSEATVPKVTIITRKAYG 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   453 GAYDVMSSKHLRGDVNYAWPTAEVAVMGAKGAVQIIFRGKQNQAEAEA--------EYVEKFANPFPAAVRGFVDDIIQP 524
Cdd:TIGR01117 402 GAYLAMCSKHLGADQVYAWPTAEIAVMGPAGAANIIFRKDIKEAKDPAatrkqkiaEYREEFANPYKAAARGYVDDVIEP 481

                         490       500
                  ....*....|....*....|..
gi 47086189   525 STTRRRICRDLEVLASKKQTNP 546
Cdd:TIGR01117 482 KQTRPKIVNALAMLESKREKLP 503
PLN02820 PLN02820
3-methylcrotonyl-CoA carboxylase, beta chain
 16-529 2.32e-85

3-methylcrotonyl-CoA carboxylase, beta chain


Pssm-ID: 178415 [Multi-domain]  Cd Length: 569  Bit Score: 275.53  E-value: 2.32e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   16 GLKCPFkCVGQTQYGVFTQSKvlqNARCYSSSHMSVQERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADS- 94
Cdd:PLN02820  22 LGKRSF-CLGVLPDGVDRNSD---AFSANSKAMEGLLSELRSHVAKVRAGGGPEAVKRHRSRNKLLPRERIDRLLDPGSp 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   95 FVEYDMFvehrcSDFGMEADQnkYPGDSVVTGQGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGL 174
Cdd:PLN02820  98 FLELSQL-----AGHELYGED--LPSGGIVTGIGPVHGRLCMFVANDPTVKGGTYYPITVKKHLRAQEIAAQCRLPCIYL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  175 NDSGGARIQEGVESLAG---YADIFL-RNVMASGVVPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSV 250
Cdd:PLN02820 171 VDSGGANLPRQAEVFPDrdhFGRIFYnQARMSSAGIPQIALVLGSCTAGGAYVPAMADESVIVKGNGTIFLAGPPLVKAA 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  251 TNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFNFLPL------SNKDSAPVVECHDPrdrLVP--GLDTVV 322
Cdd:PLN02820 251 TGEEVSAEDLGGADVHCKVSGVSDHFAQDELHALAIGRNIVKNLHLaakqgmENTLGSKNPEYKEP---LYDvkELRGIV 327

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  323 PFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVGNqpkvaSGCLDINSSVKGARFVRFCDAFNI 402
Cdd:PLN02820 328 PADHKQSFDVRSVIARIVDGSEFDEFKKNYGTTLVTGFARIYGQPVGIIGN-----NGILFTESALKGAHFIELCAQRGI 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  403 PIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLRGDVNYAWPTAEVAVMGAK 482
Cdd:PLN02820 403 PLLFLQNITGFMVGSRSEASGIAKAGAKMVMAVACAKVPKITIIVGGSFGAGNYGMCGRAYSPNFLFMWPNARIGVMGGA 482

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47086189  483 GAVQIIF---------RGKQNQAEAEA-------EYVEKFANPFPAAVRGFVDDIIQPSTTRR 529
Cdd:PLN02820 483 QAAGVLAqierenkkrQGIQWSKEEEEafkaktvEAYEREANPYYSTARLWDDGVIDPADTRR 545
 
Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
53-546 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 810.02  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  53 ERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDfgmeaDQNKYPGDSVVTGQGRING 132
Cdd:COG4799   7 AELRARREEALLGGGEKAIERQHARGKLTARERIDLLLDPGSFLELGALAGHRMYD-----DDDRVPGDGVVTGIGTVDG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 133 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLI 212
Cdd:COG4799  82 RPVVVVANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVI 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 213 MGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFN 292
Cdd:COG4799 162 MGPCAAGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLS 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 293 FLPLSNKDSAPVVECHDPrDRLVPGLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVG 372
Cdd:COG4799 242 YLPSNNLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVA 320

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 373 NQPKVASGCLDINSSVKGARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYG 452
Cdd:COG4799 321 NQPMVLAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYG 400

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 453 GAYDVMSSKHLRGDVNYAWPTAEVAVMGAKGAVQIIFRGKQNQAEAEAEYV-------EKFANPFPAAVRGFVDDIIQPS 525
Cdd:COG4799 401 AGYYAMCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRRELAAAEDPEALRaeliaeyEEQANPYYAAARGWIDDVIDPR 480

                       490       500
                ....*....|....*....|.
gi 47086189 526 TTRRRICRDLEVLASKKQTNP 546
Cdd:COG4799 481 DTRRVLARALEAAANKPEERP 501
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 73-547 0e+00

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 702.09  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189    73 AQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDFGMEadqnKYPGDSVVTGQGRINGRLVYVFSQDFTVFGGSLSGA 152
Cdd:pfam01039   1 PEHPRGKLTARERIDLLLDPGSFGELEDLFFHRATEFGRK----RIPRDGVVTGSGAVIGRAVEVVAQDFTVFGGSLGPA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   153 HAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLIMGPCAGGAVYSPALTDFTFM 232
Cdd:pfam01039  77 KGEKILRAMEIAIKTGLPLIGINDSGGARIQEGVENLRGSGKIFGRNSLASGVIPQISLIMGPCAGGGAYLPALGDFVIM 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   233 VKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFNFLPL---SNKDSAPVVECHD 309
Cdd:pfam01039 157 VEGTSPMFLTGPPVIKKVTGEEVTSEELGGATQHMTISGVSHLTALDDEDALELIRKWLSYLPKpapNNREPVPIVPTKD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   310 PRDRLVPgLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVGNQPKVASGCLDINSSVK 389
Cdd:pfam01039 237 PPDRDAP-LVSIVPDDPKKPYDVREVIAGIVDEGEFFEIKPGYAKTVVTGFARLGGIPVGVVANQPRVGAGVLFPDSADK 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   390 GARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLRGDVNY 469
Cdd:pfam01039 316 AARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKHGAKLLYALAEATVPKITVIPRKAYGGAYVVMDSKINGADINF 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   470 AWPTAEVAVMGAKGAVQIIFRGKQNQAEAE------------AEYVEKFANPFPAAVRGFVDDIIQPSTTRRRICRDLEV 537
Cdd:pfam01039 396 AWPTARIAVMGPEGAVEIKFRKEKAAAEMRgkdlaatrkqkiAEYEEELSPPYVAAARGFADAVIDPGRTRAKLVIALAA 475

                         490
                  ....*....|
gi 47086189   538 LASKKQTNPC 547
Cdd:pfam01039 476 LWTKPRFFPW 485
mmdA TIGR01117
methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA ...
 53-546 0e+00

methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130187  Cd Length: 512  Bit Score: 688.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189    53 ERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADSFVEYDMFVEHRCSDFGMeaDQNKYPGDSVVTGQGRING 132
Cdd:TIGR01117   4 EELHEKKEKIKQGGGEKRIEKQHAQGKMTARERLALLFDPGSFVEIDQFVKHRCTNFGM--DKKELPAEGVVTGYGTIDG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   133 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLI 212
Cdd:TIGR01117  82 RLVYAFAQDFTVMGGSLGEMHAAKIVKIMDLAMKMGAPVVGLNDSGGARIQEAVDALKGYGDIFYRNTIASGVVPQISAI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   213 MGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFN 292
Cdd:TIGR01117 162 MGPCAGGAVYSPALTDFIYMVDNTSQMFITGPQVIKTVTGEEVTAEQLGGAMAHNSVSGVAHFIAEDDDDCIMLIRRLLS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   293 FLPLSNKDSAPVVECHDPRDRLVPGLDTVVPFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVG 372
Cdd:TIGR01117 242 FLPSNNMEKAPLVKTGDDPTRETPELYDLLPDNPNKPYDMRDVITAIVDNGDYLEVQPYYAPNIITCFARINGQSVGIIA 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   373 NQPKVASGCLDINSSVKGARFVRFCDAFNIPIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYG 452
Cdd:TIGR01117 322 NQPKVMAGCLDIDSSDKIARFIRFCDAFNIPIVTFVDVPGFLPGVNQEYGGIIRHGAKVLYAYSEATVPKVTIITRKAYG 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   453 GAYDVMSSKHLRGDVNYAWPTAEVAVMGAKGAVQIIFRGKQNQAEAEA--------EYVEKFANPFPAAVRGFVDDIIQP 524
Cdd:TIGR01117 402 GAYLAMCSKHLGADQVYAWPTAEIAVMGPAGAANIIFRKDIKEAKDPAatrkqkiaEYREEFANPYKAAARGYVDDVIEP 481

                         490       500
                  ....*....|....*....|..
gi 47086189   525 STTRRRICRDLEVLASKKQTNP 546
Cdd:TIGR01117 482 KQTRPKIVNALAMLESKREKLP 503
PLN02820 PLN02820
3-methylcrotonyl-CoA carboxylase, beta chain
 16-529 2.32e-85

3-methylcrotonyl-CoA carboxylase, beta chain


Pssm-ID: 178415 [Multi-domain]  Cd Length: 569  Bit Score: 275.53  E-value: 2.32e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   16 GLKCPFkCVGQTQYGVFTQSKvlqNARCYSSSHMSVQERIEQKRQAALTGGGQLRIAAQHKRGKLTARERVELLLDADS- 94
Cdd:PLN02820  22 LGKRSF-CLGVLPDGVDRNSD---AFSANSKAMEGLLSELRSHVAKVRAGGGPEAVKRHRSRNKLLPRERIDRLLDPGSp 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   95 FVEYDMFvehrcSDFGMEADQnkYPGDSVVTGQGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMLVGAPVIGL 174
Cdd:PLN02820  98 FLELSQL-----AGHELYGED--LPSGGIVTGIGPVHGRLCMFVANDPTVKGGTYYPITVKKHLRAQEIAAQCRLPCIYL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  175 NDSGGARIQEGVESLAG---YADIFL-RNVMASGVVPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSV 250
Cdd:PLN02820 171 VDSGGANLPRQAEVFPDrdhFGRIFYnQARMSSAGIPQIALVLGSCTAGGAYVPAMADESVIVKGNGTIFLAGPPLVKAA 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  251 TNEDVTQEELGGAKTHTAVSGVAHRAFENDIDALLNLRDFFNFLPL------SNKDSAPVVECHDPrdrLVP--GLDTVV 322
Cdd:PLN02820 251 TGEEVSAEDLGGADVHCKVSGVSDHFAQDELHALAIGRNIVKNLHLaakqgmENTLGSKNPEYKEP---LYDvkELRGIV 327

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  323 PFESTKAYDMLDIVHGIVDEREFFEIMPNYAKNIVVGFARMNGRTVGIVGNqpkvaSGCLDINSSVKGARFVRFCDAFNI 402
Cdd:PLN02820 328 PADHKQSFDVRSVIARIVDGSEFDEFKKNYGTTLVTGFARIYGQPVGIIGN-----NGILFTESALKGAHFIELCAQRGI 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  403 PIITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLRGDVNYAWPTAEVAVMGAK 482
Cdd:PLN02820 403 PLLFLQNITGFMVGSRSEASGIAKAGAKMVMAVACAKVPKITIIVGGSFGAGNYGMCGRAYSPNFLFMWPNARIGVMGGA 482

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47086189  483 GAVQIIF---------RGKQNQAEAEA-------EYVEKFANPFPAAVRGFVDDIIQPSTTRR 529
Cdd:PLN02820 483 QAAGVLAqierenkkrQGIQWSKEEEEafkaktvEAYEREANPYYSTARLWDDGVIDPADTRR 545
AccD COG0777
Acetyl-CoA carboxylase beta subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 79-189 1.71e-18

Acetyl-CoA carboxylase beta subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase beta subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440540 [Multi-domain]  Cd Length: 280  Bit Score: 85.88  E-value: 1.71e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  79 KLTARERVELLLDADSFVEYDmfvEHRCS----DFgmeADQNKYP------------GDSVVTGQGRINGRLVYVFSQDF 142
Cdd:COG0777  55 RISARERLELLLDEGSFEELD---ADLVPvdplKF---KDSKKYKdrlkeaqkktglKDAVVTGTGTINGIPVVVAVMDF 128

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 47086189 143 TVFGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESL 189
Cdd:COG0777 129 SFMGGSMGSVVGEKITRAIERAIEKKLPLIIFSASGGARMQEGILSL 175
PRK07189 PRK07189
malonate decarboxylase subunit beta; Reviewed
 80-283 7.31e-14

malonate decarboxylase subunit beta; Reviewed


Pssm-ID: 235954  Cd Length: 301  Bit Score: 72.24  E-value: 7.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   80 LTARERVELLLDADSFVEY-DMFvEHRCS------DFGMEADqnkypgDSVVTGQGRINGRLVYVFSQDFTVFGGSLSGA 152
Cdd:PRK07189  15 ASARERAAALLDAGSFRELlGPF-ERVMSphlplqGIPPQFD------DGVVVGKGTLDGRPVVVAAQEGRFMGGSVGEV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  153 HAQKICKIMDQAMLVG-----APVIGLNDSGGARIQEGVESLAGYADIFLRNVMASGVVPQISLIMGP--CAGGAVYSPA 225
Cdd:PRK07189  88 HGAKLAGALELAAEDNrngipTAVLLLFETGGVRLQEANAGLAAIAEIMRAIVDLRAAVPVIGLIGGRvgCFGGMGIAAA 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  226 LTDfTFMVKDTSYLFITGPDVVKsvTNEDVtqEEL------------GGAktHTAVSGVAHRAFENDIDA 283
Cdd:PRK07189 168 LCS-YLIVSEEGRLGLSGPEVIE--QEAGV--EEFdsrdralvwrttGGK--HRYLSGLADALVDDDVAA 230
PRK05724 PRK05724
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated
 333-454 2.99e-09

acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated


Pssm-ID: 235580 [Multi-domain]  Cd Length: 319  Bit Score: 58.62  E-value: 2.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  333 LDIVHGIVDEreFFEIM--PNYA--KNIVVGFARMNGRTVGIVGNQpkvaSGClDINSSV-------------KGARFVR 395
Cdd:PRK05724  73 LDYIELLFTD--FTELHgdRAFAddKAIVGGLARLNGRPVMVIGHQ----KGR-DTKEKIrrnfgmprpegyrKALRLMK 145

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47086189  396 FCDAFNIPIITFVDVPGFLPG-TAQEYG---GIirhgAKLLYAFAEATVPKI-TVITRKAYGGA 454
Cdd:PRK05724 146 MAEKFGLPIITFIDTPGAYPGiGAEERGqseAI----ARNLREMARLKVPIIcTVIGEGGSGGA 205
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 333-447 8.08e-08

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 54.27  E-value: 8.08e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189 333 LDIVHGIVDEreFFEIM--PNYA--KNIVVGFARMNGRTVGIVGNQpKvasGClDINSSV-------------KGARFVR 395
Cdd:COG0825  70 LDYIEAIFTD--FIELHgdRAFGddPAIVGGLARFDGRPVMVIGHQ-K---GR-DTKERIkrnfgmphpegyrKALRLMK 142

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 47086189 396 FCDAFNIPIITFVDVPGFLPG-TAQEYG---GIirhgAKLLYAFAEATVPKITVIT 447
Cdd:COG0825 143 LAEKFGLPIITFIDTPGAYPGiGAEERGqseAI----ARNLREMARLKVPIISVVI 194
accD CHL00174
acetyl-CoA carboxylase beta subunit; Reviewed
 79-195 5.55e-07

acetyl-CoA carboxylase beta subunit; Reviewed


Pssm-ID: 214384 [Multi-domain]  Cd Length: 296  Bit Score: 51.44  E-value: 5.55e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   79 KLTARERVELLLDADSFVEYDmfvEHRCS-D-FGMEADQNKYPG------------DSVVTGQGRINGRLVYVFSQDFTV 144
Cdd:CHL00174  68 KMSSSDRIELLIDPGTWNPMD---EDMVSlDpIEFHSDEEPYKDridsyqkktgltDAVQTGIGQLNGIPVALGVMDFQF 144

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 47086189  145 FGGSLSGAHAQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESLAGYADI 195
Cdd:CHL00174 145 MGGSMGSVVGEKITRLIEYATNESLPLIIVCASGGARMQEGSLSLMQMAKI 195
PLN03230 PLN03230
acetyl-coenzyme A carboxylase carboxyl transferase; Provisional
 332-454 2.78e-05

acetyl-coenzyme A carboxylase carboxyl transferase; Provisional


Pssm-ID: 178769 [Multi-domain]  Cd Length: 431  Bit Score: 46.86  E-value: 2.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  332 MLDIVHGIVDEreFFEIMPNYA----KNIVVGFARMNGRTVGIVGNQPKVAS--------GCLDINSSVKGARFVRFCDA 399
Cdd:PLN03230 142 FLDHVLNMTDK--WVELHGDRAgfddPAIVCGIGSMEGMSFMFIGHQKGRNTkeniyrnfAMPQPNGYRKALRFMRHAEK 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  400 FNIPIITFVDVPGFLPG-TAQEYGgiirHGAKLLYAFAEA---TVPKI-TVITRKAYGGA 454
Cdd:PLN03230 220 FGFPILTFVDTPGAYAGiKAEELG----QGEAIAFNLREMfglRVPIIaTVIGEGGSGGA 275
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 77-238 4.78e-03

acetyl-CoA carboxylase subunit alpha; Provisional


Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 38.99  E-value: 4.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189   77 RGKLTARERVELLLDadSFVEydmfvehrcsdfgMEADQNKYPGDSVVTGQGRINGRLVYVFS-------QD--FTVFGG 147
Cdd:PRK12319  14 QGRLTTLDYATLIFD--DFME-------------LHGDRHFRDDGAVVGGIGYLAGQPVTVVGiqkgknlQDnlKRNFGQ 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086189  148 SLSGAHaQKICKIMDQAMLVGAPVIGLNDSGGARIQEGVESlAGYADIFLRNV--MASGVVPQISLIMGPCAGGAVYSPA 225
Cdd:PRK12319  79 PHPEGY-RKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEE-RGQGEAIARNLmeMSDLKVPIIAIIIGEGGSGGALALA 156

                        170
                 ....*....|...
gi 47086189  226 LTDFTFMVKDTSY 238
Cdd:PRK12319 157 VADQVWMLENTMY 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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