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Conserved domains on  [gi|33695101|ref|NP_892026|]
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oxidative stress-induced growth inhibitor 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltD super family cl43157
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 242-464 2.10e-09

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


The actual alignment was detected with superfamily member COG0493:

Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 59.38  E-value: 2.10e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 242 VVLATGTfDSPARLGIPGEALPFIHHELSALEAATRVGA---VTPASDPVLIIGAGLSAADA-------------VLY-- 303
Cdd:COG0493 210 VFLATGA-GKPRDLGIPGEDLKGVHSAMDFLTAVNLGEApdtILAVGKRVVVIGGGNTAMDCartalrlgaesvtIVYrr 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 304 ------ARHYNipVIHAFRRAVDdpgLVFNQLPKmlypEYH----------KVHQMmreqsilspspyegyrslprhQLL 367
Cdd:COG0493 289 treempASKEE--VEEALEEGVE---FLFLVAPV----EIIgdengrvtglECVRM---------------------ELG 338

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 368 CFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAgADFAVDpdqplsaKRNPIDVDPFTYQSTRqEGLYAmgp 447
Cdd:COG0493 339 EPDESGRRRPVPIEGSEFTLPADLVILAIGQTPDPSGLEEE-LGLELD-------KRGTIVVDEETYQTSL-PGVFA--- 406

                       250
                ....*....|....*..
gi 33695101 448 lAGDnfvrFVQGGALAV 464
Cdd:COG0493 407 -GGD----AVRGPSLVV 418
CzcO super family cl34398
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 113-301 1.69e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG2072:

Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 47.16  E-value: 1.69e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 113 KEHAIPHVVLGRN-LPGGAWH-----SIegsmVILSQGQWMGLPDLevKDWmqkkrrGLRNSRATAGDIAHYYRDYVVKK 186
Cdd:COG2072  26 RRAGIDFVVLEKAdDVGGTWRdnrypGL----RLDTPSHLYSLPFF--PNW------SDDPDFPTGDEILAYLEAYADKF 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 187 GLGHNFVSGAVVTAVEWgtpdpsscgaQDSSPLFQVSgflTRNQAQqpfsLWARNVVLATGTFDSPARLGIPGE---ALP 263
Cdd:COG2072  94 GLRRPIRFGTEVTSARW----------DEADGRWTVT---TDDGET----LTARFVVVATGPLSRPKIPDIPGLedfAGE 156

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 33695101 264 FIHhelSAleaatrvgAVTPASD----PVLIIGAGLSAADAV 301
Cdd:COG2072 157 QLH---SA--------DWRNPVDlagkRVLVVGTGASAVQIA 187
 
Name Accession Description Interval E-value
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 242-464 2.10e-09

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 59.38  E-value: 2.10e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 242 VVLATGTfDSPARLGIPGEALPFIHHELSALEAATRVGA---VTPASDPVLIIGAGLSAADA-------------VLY-- 303
Cdd:COG0493 210 VFLATGA-GKPRDLGIPGEDLKGVHSAMDFLTAVNLGEApdtILAVGKRVVVIGGGNTAMDCartalrlgaesvtIVYrr 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 304 ------ARHYNipVIHAFRRAVDdpgLVFNQLPKmlypEYH----------KVHQMmreqsilspspyegyrslprhQLL 367
Cdd:COG0493 289 treempASKEE--VEEALEEGVE---FLFLVAPV----EIIgdengrvtglECVRM---------------------ELG 338

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 368 CFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAgADFAVDpdqplsaKRNPIDVDPFTYQSTRqEGLYAmgp 447
Cdd:COG0493 339 EPDESGRRRPVPIEGSEFTLPADLVILAIGQTPDPSGLEEE-LGLELD-------KRGTIVVDEETYQTSL-PGVFA--- 406

                       250
                ....*....|....*..
gi 33695101 448 lAGDnfvrFVQGGALAV 464
Cdd:COG0493 407 -GGD----AVRGPSLVV 418
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 242-317 7.53e-08

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 54.23  E-value: 7.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  242 VVLATGTFDSpARLGIPGEALPFIHhelSALE-----AATRVGAVTPASDP------VLIIGAGLSAADAVLYARH-YNI 309
Cdd:PRK12770 122 VLIATGTWKS-RKLGIPGEDLPGVY---SALEylfriRAAKLGYLPWEKVPpvegkkVVVVGAGLTAVDAALEAVLlGAE 197


                 ....*...
gi 33695101  310 PVIHAFRR 317
Cdd:PRK12770 198 KVYLAYRR 205
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 239-455 2.07e-06

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 49.24  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   239 ARNVVLATGTfdSPARLGIPGEALPFIHHeLSALEAATRVgAVTPASDPVLIIGAGLSAADAVLYARHY--NIPVIHAFR 316
Cdd:pfam07992 110 YDRLVIATGA--RPRLPPIPGVELNVGFL-VRTLDSAEAL-RLKLLPKRVVVVGGGYIGVELAAALAKLgkEVTLIEALD 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   317 RavddpglVFNQLPKMLYPEYHKVHQMmreqsilspspyEGYRSLPRHQLLCFKEDCQAVFQDLEGvEKVFGVSLVLVLI 396
Cdd:pfam07992 186 R-------LLRAFDEEISAALEKALEK------------NGVEVRLGTSVKEIIGDGDGVEVILKD-GTEIDADLVVVAI 245

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 33695101   397 GSHPDLSFLPGAGadFAVDPdqplsakRNPIDVDPftYQSTRQEGLYAmgplAGDNFVR 455
Cdd:pfam07992 246 GRRPNTELLEAAG--LELDE-------RGGIVVDE--YLRTSVPGIYA----AGDCRVG 289
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 113-301 1.69e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 47.16  E-value: 1.69e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 113 KEHAIPHVVLGRN-LPGGAWH-----SIegsmVILSQGQWMGLPDLevKDWmqkkrrGLRNSRATAGDIAHYYRDYVVKK 186
Cdd:COG2072  26 RRAGIDFVVLEKAdDVGGTWRdnrypGL----RLDTPSHLYSLPFF--PNW------SDDPDFPTGDEILAYLEAYADKF 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 187 GLGHNFVSGAVVTAVEWgtpdpsscgaQDSSPLFQVSgflTRNQAQqpfsLWARNVVLATGTFDSPARLGIPGE---ALP 263
Cdd:COG2072  94 GLRRPIRFGTEVTSARW----------DEADGRWTVT---TDDGET----LTARFVVVATGPLSRPKIPDIPGLedfAGE 156

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 33695101 264 FIHhelSAleaatrvgAVTPASD----PVLIIGAGLSAADAV 301
Cdd:COG2072 157 QLH---SA--------DWRNPVDlagkRVLVVGTGASAVQIA 187
 
Name Accession Description Interval E-value
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 242-464 2.10e-09

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 59.38  E-value: 2.10e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 242 VVLATGTfDSPARLGIPGEALPFIHHELSALEAATRVGA---VTPASDPVLIIGAGLSAADA-------------VLY-- 303
Cdd:COG0493 210 VFLATGA-GKPRDLGIPGEDLKGVHSAMDFLTAVNLGEApdtILAVGKRVVVIGGGNTAMDCartalrlgaesvtIVYrr 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 304 ------ARHYNipVIHAFRRAVDdpgLVFNQLPKmlypEYH----------KVHQMmreqsilspspyegyrslprhQLL 367
Cdd:COG0493 289 treempASKEE--VEEALEEGVE---FLFLVAPV----EIIgdengrvtglECVRM---------------------ELG 338

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 368 CFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAgADFAVDpdqplsaKRNPIDVDPFTYQSTRqEGLYAmgp 447
Cdd:COG0493 339 EPDESGRRRPVPIEGSEFTLPADLVILAIGQTPDPSGLEEE-LGLELD-------KRGTIVVDEETYQTSL-PGVFA--- 406

                       250
                ....*....|....*..
gi 33695101 448 lAGDnfvrFVQGGALAV 464
Cdd:COG0493 407 -GGD----AVRGPSLVV 418
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 242-317 7.53e-08

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 54.23  E-value: 7.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  242 VVLATGTFDSpARLGIPGEALPFIHhelSALE-----AATRVGAVTPASDP------VLIIGAGLSAADAVLYARH-YNI 309
Cdd:PRK12770 122 VLIATGTWKS-RKLGIPGEDLPGVY---SALEylfriRAAKLGYLPWEKVPpvegkkVVVVGAGLTAVDAALEAVLlGAE 197


                 ....*...
gi 33695101  310 PVIHAFRR 317
Cdd:PRK12770 198 KVYLAYRR 205
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
236-317 3.96e-07

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 52.26  E-value: 3.96e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 236 SLWARNVVLATGTFdSPARLGIPGEALPFIHHELSALEAATRVgavtPASDPVLIIGAGLSAADAVLY--ARHYNIPvIH 313
Cdd:COG4529 148 TLRADAVVLATGHP-PPAPPPGLAAGSPRYIADPWPPGALARI----PPDARVLIIGTGLTAIDVVLSlaARGHRGP-IT 221


                ....
gi 33695101 314 AFRR 317
Cdd:COG4529 222 ALSR 225
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
239-451 1.08e-06

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 50.12  E-value: 1.08e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 239 ARNVVLATGTfdSPARLGIPGEAlPFIHHELSAleAATRVGAVTPASDpVLIIGAGLSAADAVLYARHY--NIPVIHafR 316
Cdd:COG0492 101 AKAVIIATGA--GPRKLGLPGEE-EFEGRGVSY--CATCDGFFFRGKD-VVVVGGGDSALEEALYLTKFasKVTLIH--R 172

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 317 RavDDPglvfnqlpkMLYPEYhkVHQMMREQSIlspspyegyRSLPRHQLLCFKEDCQ---AVFQDLE-GVEKVFGVSLV 392
Cdd:COG0492 173 R--DEL---------RASKIL--VERLRANPKI---------EVLWNTEVTEIEGDGRvegVTLKNVKtGEEKELEVDGV 230

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 33695101 393 LVLIGSHPDLSFLPGAGADfaVDPDqplsakrNPIDVDPftYQSTRQEGLYAmgplAGD 451
Cdd:COG0492 231 FVAIGLKPNTELLKGLGLE--LDED-------GYIVVDE--DMETSVPGVFA----AGD 274
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 239-455 2.07e-06

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 49.24  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   239 ARNVVLATGTfdSPARLGIPGEALPFIHHeLSALEAATRVgAVTPASDPVLIIGAGLSAADAVLYARHY--NIPVIHAFR 316
Cdd:pfam07992 110 YDRLVIATGA--RPRLPPIPGVELNVGFL-VRTLDSAEAL-RLKLLPKRVVVVGGGYIGVELAAALAKLgkEVTLIEALD 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   317 RavddpglVFNQLPKMLYPEYHKVHQMmreqsilspspyEGYRSLPRHQLLCFKEDCQAVFQDLEGvEKVFGVSLVLVLI 396
Cdd:pfam07992 186 R-------LLRAFDEEISAALEKALEK------------NGVEVRLGTSVKEIIGDGDGVEVILKD-GTEIDADLVVVAI 245

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 33695101   397 GSHPDLSFLPGAGadFAVDPdqplsakRNPIDVDPftYQSTRQEGLYAmgplAGDNFVR 455
Cdd:pfam07992 246 GRRPNTELLEAAG--LELDE-------RGGIVVDE--YLRTSVPGIYA----AGDCRVG 289
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 242-464 3.00e-06

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 49.41  E-value: 3.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  242 VVLATGTFdSPARLGIPGEALPFIHhelSALEAATRVGAVTPASDP-----VLIIGAGLSAADAV-----LYARHYNIpv 311
Cdd:PRK11749 229 VFIGTGAG-LPRFLGIPGENLGGVY---SAVDFLTRVNQAVADYDLpvgkrVVVIGGGNTAMDAArtakrLGAESVTI-- 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  312 ihAFRRAVDD-PG--------------LVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPrhqllcfkedcqav 376
Cdd:PRK11749 303 --VYRRGREEmPAseeevehakeegveFEWLAAPVEILGDEGRVTGVEFVRMELGEPDASGRRRVP-------------- 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  377 fqdLEGVEKVFGVSLVLVLIGSHPDLSFLPGAgadfavdPDQPLSAKRNPIdVDPFTYQSTRqEGLYAmgplAGDnfvrF 456
Cdd:PRK11749 367 ---IEGSEFTLPADLVIKAIGQTPNPLILSTT-------PGLELNRWGTII-ADDETGRTSL-PGVFA----GGD----I 426


                 ....*...
gi 33695101  457 VQGGALAV 464
Cdd:PRK11749 427 VTGAATVV 434
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
160-450 1.41e-05

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 46.83  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   160 KKRRGLRNSRATAGDIAHYYRDYVVKKGLghNFVSGAVVTAVEwgtpdpsscgAQDSspLFQVSgflTRNQAQQpfslwA 239
Cdd:pfam13738  62 SPAFTFNREHPSGNEYAEYLRRVADHFEL--PINLFEEVTSVK----------KEDD--GFVVT---TSKGTYQ-----A 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   240 RNVVLATGTFDSPARLGIPGeaLPFIHHELSALEAatrvgavtPASDPVLIIGAGLSAADAV--LYARHYNIPVIHAfrr 317
Cdd:pfam13738 120 RYVIIATGEFDFPNKLGVPE--LPKHYSYVKDFHP--------YAGQKVVVIGGYNSAVDAAleLVRKGARVTVLYR--- 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   318 avDDPGLVFNQLPKmlypeYHkvhqmmreqsiLSPSPYEGYRSLPRHQLL---------CFKEDCQAVFQDLEGVEKVFG 388
Cdd:pfam13738 187 --GSEWEDRDSDPS-----YS-----------LSPDTLNRLEELVKNGKIkahfnaevkEITEVDVSYKVHTEDGRKVTS 248

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 33695101   389 VSLVLVLIGSHPDLSFLPGAGadFAVDPDQ-PLsakrnpidVDPFTyQSTRQEGLYamgpLAG 450
Cdd:pfam13738 249 NDDPILATGYHPDLSFLKKGL--FELDEDGrPV--------LTEET-ESTNVPGLF----LAG 296
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 113-301 1.69e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 47.16  E-value: 1.69e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 113 KEHAIPHVVLGRN-LPGGAWH-----SIegsmVILSQGQWMGLPDLevKDWmqkkrrGLRNSRATAGDIAHYYRDYVVKK 186
Cdd:COG2072  26 RRAGIDFVVLEKAdDVGGTWRdnrypGL----RLDTPSHLYSLPFF--PNW------SDDPDFPTGDEILAYLEAYADKF 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 187 GLGHNFVSGAVVTAVEWgtpdpsscgaQDSSPLFQVSgflTRNQAQqpfsLWARNVVLATGTFDSPARLGIPGE---ALP 263
Cdd:COG2072  94 GLRRPIRFGTEVTSARW----------DEADGRWTVT---TDDGET----LTARFVVVATGPLSRPKIPDIPGLedfAGE 156

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 33695101 264 FIHhelSAleaatrvgAVTPASD----PVLIIGAGLSAADAV 301
Cdd:COG2072 157 QLH---SA--------DWRNPVDlagkRVLVVGTGASAVQIA 187
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 242-451 3.64e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 42.84  E-value: 3.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  242 VVLATGTFdSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDP-------VLIIGAGLSAADAVLYA-RH------- 306
Cdd:PRK12810 232 VFLGTGAY-KPRDLGIPGRDLDGVHFAMDFLIQNTRRVLGDETEPFisakgkhVVVIGGGDTGMDCVGTAiRQgaksvtq 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  307 ---YNIPvihAFRRAVDDPglvfnqlpkmlYPEYHKVHQMmreqsilSPSPYEGyrsLPRH---QLLCFK---------- 370
Cdd:PRK12810 311 rdiMPMP---PSRRNKNNP-----------WPYWPMKLEV-------SNAHEEG---VEREfnvQTKEFEgengkvtgvk 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101  371 ----EDCQAVFQDLEGVEKVFGVSLVLVLIG-SHPDLSFLpgagADFAVDPDQplsakRNPIDVDPFTYQsTRQEGLYAm 445
Cdd:PRK12810 367 vvrtELGEGDFEPVEGSEFVLPADLVLLAMGfTGPEAGLL----AQFGVELDE-----RGRVAAPDNAYQ-TSNPKVFA- 435


                 ....*.
gi 33695101  446 gplAGD 451
Cdd:PRK12810 436 ---AGD 438
IucD COG3486
Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism] ...
 195-303 5.01e-04

Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442709 [Multi-domain]  Cd Length: 440  Bit Score: 42.46  E-value: 5.01e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101 195 GAVVTAVEWgtpdpsscgaQDSSPLFQVSgflTRNQAQQPFSLWARNVVLATGTfdSPArlgIPGEALPFIHHE------ 268
Cdd:COG3486 118 GTEVEAVEY----------DDDAGAFRVT---VRDGTGERETYRARNLVLGTGT--RPY---LPECFRGLPGERvfhsse 179

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 33695101 269 -LSALEAATRVGAVTpasdpvlIIGAGLSAADAVLY 303
Cdd:COG3486 180 yLHRKEDLQAAKRVT-------VVGSGQSAAEIFLD 208
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
243-295 3.81e-03

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 39.35  E-value: 3.81e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 33695101 243 VLATGTfdSPARLGIPGEALPFIHHeLSALEAATRVGAVTPASDPVLIIGAGL 295
Cdd:COG1251 103 VLATGS--RPRVPPIPGADLPGVFT-LRTLDDADALRAALAPGKRVVVIGGGL 152
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 195-318 4.46e-03

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 39.11  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33695101   195 GAVVTAVEwgtPDPSscgaqDSSPLFQVSgflTRNQAQQPFSLWARNVVLATGTfdSPArlgIPGEAL---PFIHhelSA 271
Cdd:pfam13434 115 GQEVESVE---PDAE-----RGEPLLRVR---VRDADGEETTFLARNLVLGTGG--EPY---IPECARggeRVFH---SS 175

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 33695101   272 LEAATRVGAVTPASdpVLIIGAGLSAADaVLYARHYNIPV--IHAFRRA 318
Cdd:pfam13434 176 EYLERIDRLAAKKR--IAVVGSGQSAAE-IFRDLLRRGPAyeLTWVTRS 221
PRK07710 PRK07710
acetolactate synthase large subunit;
240-313 4.85e-03

acetolactate synthase large subunit;


Pssm-ID: 236076 [Multi-domain]  Cd Length: 571  Bit Score: 39.36  E-value: 4.85e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33695101  240 RNVVLATGTFDSPARLGIPGEAlPfiHHELSALEAATRVGAVTPASDPVLIIGAGLSAADA----VLYARHYNIPVIH 313
Cdd:PRK07710 174 KDMVVEEGEFCYDVQMDLPGYQ-P--NYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKAskelTSYAEQQEIPVVH 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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