NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|24638837|ref|NP_726658|]
View 

uncharacterized protein Dmel_CG3038, isoform B [Drosophila melanogaster]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229488)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Galactosyl_T super family cl21608
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 73-267 1.87e-29

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


The actual alignment was detected with superfamily member pfam01762:

Pssm-ID: 473923 [Multi-domain]  Cd Length: 195  Bit Score: 112.03  E-value: 1.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837    73 AHRQAI-----PQSKLEEMGLRRVFLLAALPSREHFIsQDQLASEQNRFGDLLQGNFIEDYRNLSYKHVMGLKWVSEECK 147
Cdd:pfam01762   1 ARRNAIrktwmNQGNSEGGRIKSLFLVGLSADTDGKV-ADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837   148 kQAKFIIKLDDDIIYDVFHLRRYLEtlevrEPGLATSSTLLSGYVLDAKPPIRLRANKWYVSKKEYPQALYPAYLSGWLY 227
Cdd:pfam01762  80 -SAKYIGKIDDDVYFFPDKLLSLLD-----NGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFY 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 24638837   228 VTNVPTAERIVAEAERMSFFWIDDtWLTGVVRTRLGIPLE 267
Cdd:pfam01762 154 VLSRDAAEKLLKASKHRRFLQIED-VYVGILANDLGISRV 192
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 73-267 1.87e-29

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 112.03  E-value: 1.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837    73 AHRQAI-----PQSKLEEMGLRRVFLLAALPSREHFIsQDQLASEQNRFGDLLQGNFIEDYRNLSYKHVMGLKWVSEECK 147
Cdd:pfam01762   1 ARRNAIrktwmNQGNSEGGRIKSLFLVGLSADTDGKV-ADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837   148 kQAKFIIKLDDDIIYDVFHLRRYLEtlevrEPGLATSSTLLSGYVLDAKPPIRLRANKWYVSKKEYPQALYPAYLSGWLY 227
Cdd:pfam01762  80 -SAKYIGKIDDDVYFFPDKLLSLLD-----NGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFY 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 24638837   228 VTNVPTAERIVAEAERMSFFWIDDtWLTGVVRTRLGIPLE 267
Cdd:pfam01762 154 VLSRDAAEKLLKASKHRRFLQIED-VYVGILANDLGISRV 192
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 107-237 7.52e-05

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 44.41  E-value: 7.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837  107 DQLASEQNRFGDLLQGNFIEDYRNLSYKH----VMGLKWVSeeckkqAKFIIKLDDDIIYDVFHLRRYLETLEVrepgla 182
Cdd:PLN03133 435 EELWNEARTYGDIQLMPFVDYYSLITWKTlaicIFGTEVVS------AKYVMKTDDDAFVRVDEVLASLKRTNV------ 502

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 24638837  183 tSSTLLSGYVLDAKPPIRLRANKWYVSKKEYPQALYPAYLSGWLYVTNVPTAERI 237
Cdd:PLN03133 503 -SHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEV 556
 
Name Accession Description Interval E-value
Galactosyl_T pfam01762
Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose: ...
 73-267 1.87e-29

Galactosyltransferase; This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2.


Pssm-ID: 426415 [Multi-domain]  Cd Length: 195  Bit Score: 112.03  E-value: 1.87e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837    73 AHRQAI-----PQSKLEEMGLRRVFLLAALPSREHFIsQDQLASEQNRFGDLLQGNFIEDYRNLSYKHVMGLKWVSEECK 147
Cdd:pfam01762   1 ARRNAIrktwmNQGNSEGGRIKSLFLVGLSADTDGKV-ADLVMEEAKLYGDIVVVDFEDTYENLTFKTLTGLLWAVSKCP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837   148 kQAKFIIKLDDDIIYDVFHLRRYLEtlevrEPGLATSSTLLSGYVLDAKPPIRLRANKWYVSKKEYPQALYPAYLSGWLY 227
Cdd:pfam01762  80 -SAKYIGKIDDDVYFFPDKLLSLLD-----NGNIDPSESSFYGYVMEEGPVIRNKKSKWYVSPSDYKCSRYPPYASGPFY 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 24638837   228 VTNVPTAERIVAEAERMSFFWIDDtWLTGVVRTRLGIPLE 267
Cdd:pfam01762 154 VLSRDAAEKLLKASKHRRFLQIED-VYVGILANDLGISRV 192
PLN03133 PLN03133
beta-1,3-galactosyltransferase; Provisional
 107-237 7.52e-05

beta-1,3-galactosyltransferase; Provisional


Pssm-ID: 215596 [Multi-domain]  Cd Length: 636  Bit Score: 44.41  E-value: 7.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24638837  107 DQLASEQNRFGDLLQGNFIEDYRNLSYKH----VMGLKWVSeeckkqAKFIIKLDDDIIYDVFHLRRYLETLEVrepgla 182
Cdd:PLN03133 435 EELWNEARTYGDIQLMPFVDYYSLITWKTlaicIFGTEVVS------AKYVMKTDDDAFVRVDEVLASLKRTNV------ 502

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 24638837  183 tSSTLLSGYVLDAKPPIRLRANKWYVSKKEYPQALYPAYLSGWLYVTNVPTAERI 237
Cdd:PLN03133 503 -SHGLLYGLINSDSQPHRNPDSKWYISPEEWPEETYPPWAHGPGYVVSRDIAKEV 556
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH