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Conserved domains on  [gi|46909607|ref|NP_631883|]
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UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform 1 [Mus musculus]

Protein Classification

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase( domain architecture ID 18657010)

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase, also called O-linked N-acetylglucosamine transferase (OGT), is a glycosyltransferase family 41 protein containing tetratricopeptide (TPR) repeats that catalyzes the addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 476-1016 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


:

Pssm-ID: 404688  Cd Length: 543  Bit Score: 1175.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    476 VCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 555
Cdd:pfam13844    1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    556 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 635
Cdd:pfam13844   81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    636 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 715
Cdd:pfam13844  161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    716 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNPDSSNTALNMPVIPMNTiAEAVIEMINR 792
Cdd:pfam13844  241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    793 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 872
Cdd:pfam13844  320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    873 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 952
Cdd:pfam13844  400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    953 SRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMEL 1016
Cdd:pfam13844  480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 190-457 1.46e-50

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 179.92  E-value: 1.46e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269
Cdd:COG2956    7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  270 YEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRL 349
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  350 YRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAfA 429
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-D 245

                        250       260
                 ....*....|....*....|....*...
gi 46909607  430 DAHSNLASIHKDSGNIPEAIASYRTALK 457
Cdd:COG2956  246 DLLLALADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-289 1.90e-41

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 152.47  E-value: 1.90e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   82 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRS 161
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  162 DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 241
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  242 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
32-121 8.27e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


:

Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.19  E-value: 8.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   32 YQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTlAIKQNPLLAEAYSNLGNVYKERGQLQEAIEH 111
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 46909607  112 YRHALRLKPD 121
Cdd:COG3063   82 LERALELDPS 91
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 476-1016 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1175.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    476 VCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 555
Cdd:pfam13844    1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    556 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 635
Cdd:pfam13844   81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    636 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 715
Cdd:pfam13844  161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    716 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNPDSSNTALNMPVIPMNTiAEAVIEMINR 792
Cdd:pfam13844  241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    793 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 872
Cdd:pfam13844  320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    873 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 952
Cdd:pfam13844  400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    953 SRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMEL 1016
Cdd:pfam13844  480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 246-1027 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 585.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  246 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  326 HADSLNNLanikREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTL 405
Cdd:COG3914   81 LELAALLL----QALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  406 KEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDER 485
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  486 MKKLvsivaEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPPYEHPKDLKLSDGRLRVGYVSSDF 565
Cdd:COG3914  237 EELL-----AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPELPPPPNPRDPDRKLRIGYVSADF 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  566 GNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNGKAADRIHQDGIHILVNMNGYTKG 645
Cdd:COG3914  308 RRHAVGYLLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DEEAAELIRADGIDILVDLSGHTAG 385

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  646 ARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFigdhanmfphlkkkavidfks 725
Cdd:COG3914  386 NRLGVFALRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGSYL--------------------- 444

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  726 nghiydnrivlngidlkafldslpdvkivkmkCPDGGDnpdssntalNMPVIPmntiaeavieminrgqiqitingfsis 805
Cdd:COG3914  445 --------------------------------CYQPND---------RAPEVA--------------------------- 456

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  806 nglattqinnkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFP-AVGEP 884
Cdd:COG3914  457 ----------------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWARILKAVPNSVLLLKGGGlPEARE 514

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  885 NIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLG 964
Cdd:COG3914  515 RLRAAAAARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGVPVVTLAGETFASRVGASLLTALG 594

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607  965 CLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHY 1027
Cdd:COG3914  595 LPELIATSEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYRQMWQRW 657
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 190-457 1.46e-50

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 179.92  E-value: 1.46e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269
Cdd:COG2956    7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  270 YEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRL 349
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  350 YRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAfA 429
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-D 245

                        250       260
                 ....*....|....*....|....*...
gi 46909607  430 DAHSNLASIHKDSGNIPEAIASYRTALK 457
Cdd:COG2956  246 DLLLALADLLERKEGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-465 9.90e-42

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 165.64  E-value: 9.90e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     22 QGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKE 101
Cdd:TIGR02917  228 AVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQ 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    102 RGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYL 181
Cdd:TIGR02917  308 LGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLA 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    182 KAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVV 261
Cdd:TIGR02917  388 KATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASL 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    262 HGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Cdd:TIGR02917  468 HNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    342 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA 421
Cdd:TIGR02917  548 NEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 46909607    422 IQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 465
Cdd:TIGR02917  628 LALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-289 1.90e-41

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 152.47  E-value: 1.90e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   82 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRS 161
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  162 DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 241
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  242 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-281 2.91e-24

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 109.79  E-value: 2.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     20 SFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVY 99
Cdd:TIGR02917  634 SALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLY 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    100 KERGQLQEAIEHYRHALRLKPDfIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAC 179
Cdd:TIGR02917  714 LRQKDYPAAIQAYRKALKRAPS-SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKH 792

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    180 YLKAIETQPNFAVAWSNLGCVFnAQGEIWLAIHHFEKAVTL---DPNFLDAYinlGNVLKEARIFDRAVAAYLRALSLSP 256
Cdd:TIGR02917  793 YQTVVKKAPDNAVVLNNLAWLY-LELKDPRALEYAERALKLapnIPAILDTL---GWLLVEKGEADRALPLLRKAVNIAP 868

                          250       260
                   ....*....|....*....|....*
gi 46909607    257 NHAVVHGNLACVYYEQGLIDLAIDT 281
Cdd:TIGR02917  869 EAAAIRYHLALALLATGRKAEARKE 893
gliding_GltE NF033758
adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a ...
 214-470 2.23e-15

adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a tetratricopeptide repeat protein with a lipoprotein signal peptide and a role in A-motility (adventurous gliding motility) in Myxococcus xanthus and other delta-proteobacteria.


Pssm-ID: 468174 [Multi-domain]  Cd Length: 411  Bit Score: 79.48  E-value: 2.23e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   214 FEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPnhavvhgnlacvyyeqglidlaidTYRRAIElqphfp 293
Cdd:NF033758   75 FKAALEADPNLAEAEYNLGVLAERQGKTDEAVARYKAALKKKP------------------------TLRQASE------ 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   294 daycNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA---------- 363
Cdd:NF033758  125 ----NLAVMAQNAGDVAGAVALYQDVLKRYPDDASSRARLAEIYRQTGDHDKAMELSRAALMRDPQSTTAlkvmmrsyld 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   364 ------------------------HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 419
Cdd:NF033758  201 rkqlamaklvalravkidqndpelHHTVGLILLQEGDKDGARLQFKRALEVRADYVPSHVELAQLALDAEDYPGAEEHLR 280

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 46909607   420 RAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 470
Cdd:NF033758  281 RILQADGKNAAAHLNLGVAYKGQGQYDKAMQEYDEAEKLDPELAAIYLNRA 331
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 293-392 7.97e-13

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 69.50  E-value: 7.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ 372
Cdd:NF033920  156 PLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALA 235

                          90       100
                  ....*....|....*....|
gi 46909607   373 QQGKLQEALMHYKEAIRISP 392
Cdd:NF033920  236 AQGCTAQARAAAECALALAP 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
32-121 8.27e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.19  E-value: 8.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   32 YQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTlAIKQNPLLAEAYSNLGNVYKERGQLQEAIEH 111
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 46909607  112 YRHALRLKPD 121
Cdd:COG3063   82 LERALELDPS 91
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 167-357 5.11e-12

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 68.04  E-value: 5.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  167 LKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN-FLDAYINLGNVL--KEA-RIFD 242
Cdd:cd24142   10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLGQLSggEEAlQYYE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  243 RAVAAYLRALslspnhavvhgnlacvyyeQGLIDLAIDTYRRAIELQPHFPDAYCNLA-----NALKEKGSVAEAEDCYN 317
Cdd:cd24142   90 KGIEILEEEL-------------------QALQAASAEAEEEAEELKRKLSSALCALAeiymtDLCDEPDAEQRCEELIT 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 46909607  318 TALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVF 357
Cdd:cd24142  151 KALELDPTNPEALQTLASLRISQQRPDEAKEALRRSLELW 190
TPR_12 pfam13424
Tetratricopeptide repeat;
327-390 9.24e-12

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 61.63  E-value: 9.24e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 390
Cdd:pfam13424    3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 23-393 7.48e-11

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 66.65  E-value: 7.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    23 GLAELAHREyqaGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQ--------NPLLAEAYSN 94
Cdd:PRK11447  390 GLGDVAMAR---KDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQSPEKALAFIASLSASQrrsiddieRSLQNDRLAQ 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    95 LGNVYKERGQLQEAIEHYRHALRLKPDfiDGYIN--LAAALVAAGDMEGAVQAYVSALQYNPdlycvrsdlgnllkalGR 172
Cdd:PRK11447  467 QAEALENQGKWAQAAELQRQRLALDPG--SVWLTyrLAQDLRQAGQRSQADALMRRLAQQKP----------------ND 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   173 LEE--AKACYLKAIEtQPNFAVAwsNLGCVFNAQgeiWLA-IHHFEKAVTLDpNFLDAYINLGNVLKEArifdrAVAAYL 249
Cdd:PRK11447  529 PEQvyAYGLYLSGSD-RDRAALA--HLNTLPRAQ---WNSnIQELAQRLQSD-QVLETANRLRDSGKEA-----EAEALL 596

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   250 RALSLSPNHAVVhgnLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEdcynTALRLCPTHA-D 328
Cdd:PRK11447  597 RQQPPSTRIDLT---LADWAQQRGDYAAARAAYQRVLTREPGNADARLGLIEVDIAQGDLAAAR----AQLAKLPATAnD 669

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607   329 SLN---NLANIKREQGNIEEAVRLYR------KALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI---RISPT 393
Cdd:PRK11447  670 SLNtqrRVALAWAALGDTAAAQRTFNrlipqaKSQPPSMESALVLRDAARFEAQTGQPQQALETYKDAMvasGITPT 746
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 8-381 5.56e-10

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 63.40  E-value: 5.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     8 VADSTEPTKRMLsfqgLAELAHREYQAGDFEAAERHC---MQLWRQ--EPDNTGVLLL---LSSIHFQ------CRRLDR 73
Cdd:NF040586  383 ALESDDPEVRRL----LLDQVRYLYLRGDYESARDLAeraLERWRErlGPDDRQTLRLrfhLANALRSlgryeeARELDE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    74 SA-------------HFSTLAikqnpllaeAYSNLGNVYKERGQLQEAIEHYRHALR-----LKPDfiDGYI-----NLA 130
Cdd:NF040586  459 DTlerqrrvlglgedHPHTLM---------TAGGLGADLRALGRFREALELDEETLErhrrvFGED--HPRTlraanNLA 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   131 AALVAAGDmegavqaYVSALQYNPDLYCVRSDLGNllkalgrleeakacylkaiETQPNFAVAWSNLGCVFNAQGEiwla 210
Cdd:NF040586  528 VSLRLLGD-------YREALELDREVLRRRRRVLG-------------------PDHPRTLLSANNLARDLRELGR---- 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   211 ihhFEKAVTLdpnfldayinlgnvLKEARifdravaAYLRALSLSPNHAVVHG---NLA-----CVYYEQGLiDLAIDTY 282
Cdd:NF040586  578 ---YAEALDL--------------LEEAL-------ERYREVLGGPDHPDTLRaakSLAvalrrAGRLEEAL-ELAEDTY 632

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   283 RRAIELQ-PHFPD---AYCNLANALKEKG----SVAEAEDCYNT-ALRLCPTHADSL---NNLANIKREQGNIEEAVRLY 350
Cdd:NF040586  633 ERYRRRFgPDHPDtlaAALSLANDLRALGdadeARELAREVLDRyRRVLGEDHPFTLacrNNLAVLLRALGDPEEARELA 712

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 46909607   351 RKALEVFPE----------FAAAhsNLASVLQQQGKLQEAL 381
Cdd:NF040586  713 EAALEGLRErlgpdhpytlAAAV--NLANDLAALGDLDAAL 751
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 81-154 1.06e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 60.26  E-value: 1.06e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 154
Cdd:NF033920  182 ATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR_1 pfam00515
Tetratricopeptide repeat;
89-122 1.78e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 50.88  E-value: 1.78e-08
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDF 122
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 89-122 7.11e-08

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 49.37  E-value: 7.11e-08
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607      89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDF 122
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 266-358 2.28e-07

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 53.32  E-value: 2.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   266 ACVYYEQ-GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE 344
Cdd:NF033920  162 AAQDLEQtGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTA 241

                          90
                  ....*....|....
gi 46909607   345 EAVRLYRKALEVFP 358
Cdd:NF033920  242 QARAAAECALALAP 255
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 237-508 3.85e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 51.07  E-value: 3.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   237 EARIFDRAVAAYLRALsLSPNHA---VVHGNLACVY-----YEQGLiDLAIDTYRRAIELQPhfPD------AYCNLANA 302
Cdd:NF040586  496 EALELDEETLERHRRV-FGEDHPrtlRAANNLAVSLrllgdYREAL-ELDREVLRRRRRVLG--PDhprtllSANNLARD 571

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   303 LKEKGSVAEAEDCYNTALRLC------PTHADSLN---NLANIKREQGNIEEAVRL----YRKALEVF----PEFAAAHS 365
Cdd:NF040586  572 LRELGRYAEALDLLEEALERYrevlggPDHPDTLRaakSLAVALRRAGRLEEALELaedtYERYRRRFgpdhPDTLAAAL 651

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   366 NLASVLQQQGKLQEALMHYKEAIRISP---------TFAdAYSNMGNTLKEMQDVQGALQCYTRAI-QINPAFADAH--- 432
Cdd:NF040586  652 SLANDLRALGDADEARELAREVLDRYRrvlgedhpfTLA-CRNNLAVLLRALGDPEEARELAEAALeGLRERLGPDHpyt 730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   433 ----SNLASIHKDSGNIPEAIAS---------YRTALKLKPDFPD---AYCNLAHCLQIvcdwTDYDERMKKLVSIVAEQ 496
Cdd:NF040586  731 laaaVNLANDLAALGDLDAALGEealerlrrlLGEDLRAGPDHPDtlaCAANLALDLRA----TGRTEEAEELRADTLAR 806

                         330
                  ....*....|..
gi 46909607   497 LEKnRLPSVHPH 508
Cdd:NF040586  807 LRR-VLGPDHPD 817
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 34-372 6.21e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 50.30  E-value: 6.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    34 AGDFEAAERHCMQLWRQEpdntgvllllssihfqcRRLDRSAHFSTLAikqnpllaeAYSNLGNVYKERGQLQEAIEHYR 113
Cdd:NF040586  533 LGDYREALELDREVLRRR-----------------RRVLGPDHPRTLL---------SANNLARDLRELGRYAEALDLLE 586

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   114 HALR------LKPDFIDGYI---NLAAALVAAGDMEGA-------VQAYVSALQ-YNPDLYCVRSDLGNLLKALGRLEEA 176
Cdd:NF040586  587 EALEryrevlGGPDHPDTLRaakSLAVALRRAGRLEEAlelaedtYERYRRRFGpDHPDTLAAALSLANDLRALGDADEA 666

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   177 kacyLKAIETqpnfavawsnlgcvfnaqgeiwlAIHHFEKAVTLD-PNFLDAYINLGNVLK------EARIFDRAVAAYL 249
Cdd:NF040586  667 ----RELARE-----------------------VLDRYRRVLGEDhPFTLACRNNLAVLLRalgdpeEARELAEAALEGL 719

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   250 RAlSLSPNH------AVvhgNLACVYYEQGLIDLAIDTyrraielqphfpdaycnlanalkekGSVAEAEDCYNTALRLC 323
Cdd:NF040586  720 RE-RLGPDHpytlaaAV---NLANDLAALGDLDAALGE-------------------------EALERLRRLLGEDLRAG 770

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 46909607   324 PTHADSL---NNLANIKREQGNIEEAVRLYRKALEVFPE-FAAAHSNLASVLQ 372
Cdd:NF040586  771 PDHPDTLacaANLALDLRATGRTEEAEELRADTLARLRRvLGPDHPDTVAARE 823
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 327-360 2.05e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 2.05e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 360
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 87-288 2.66e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.24  E-value: 2.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   87 LLAEAysnlgNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD------LYcvr 160
Cdd:cd24142    3 LLEKA-----EELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDggyekyLY--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  161 sdLGNLLKAlgrlEEAKACYLKAIE-------TQPNFAVAWSNLGCVFNAQ--------GEIWLAIHHFEKavtldpnfl 225
Cdd:cd24142   75 --LGQLSGG----EEALQYYEKGIEileeelqALQAASAEAEEEAEELKRKlssalcalAEIYMTDLCDEP--------- 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607  226 DAyinlgnvlkEARifdraVAAYL-RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Cdd:cd24142  140 DA---------EQR-----CEELItKALELDPTNPEALQTLASLRISQQRPDEAKEALRRSLEL 189
TPR_12 pfam13424
Tetratricopeptide repeat;
24-121 2.74e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     24 LAELAHREYQAGDFEAAERH---CMQLWRQEPDntgvllllssihfqcrrldrsahfstlaiKQNPLLAEAYSNLGNVYK 100
Cdd:pfam13424    6 LNNLAAVLRRLGRYDEALELlekALEIARRLLG-----------------------------PDHPLTATTLLNLGRLYL 56

                           90       100
                   ....*....|....*....|.
gi 46909607    101 ERGQLQEAIEHYRHALRLKPD 121
Cdd:pfam13424   57 ELGRYEEALELLERALALAEK 77
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 103-236 3.03e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 45.43  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   103 GQLQEAIEHYRHALRLKPDFID-GYI--NLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAc 179
Cdd:PRK02603   49 GEYAEALENYEEALKLEEDPNDrSYIlyNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKAEEAG- 127

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607   180 ylkaietQPNFAVAWsnlgcvFNAQGEIWlaihhfEKAVTLDPNfldAYINLGNVLK 236
Cdd:PRK02603  128 -------DQDEAEAL------FDKAAEYW------KQAIRLAPN---NYIEAQNWLK 162
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 750-830 3.03e-04

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 40.73  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   750 DVKIVKMKCPDGGDNPDSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 828
Cdd:NF038028    1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                  ..
gi 46909607   829 VT 830
Cdd:NF038028   70 FT 71
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 210-290 3.70e-04

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 43.31  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:NF033920  175 ALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALA 254


                  .
gi 46909607   290 P 290
Cdd:NF033920  255 P 255
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 476-1016 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1175.26  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    476 VCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 555
Cdd:pfam13844    1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    556 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 635
Cdd:pfam13844   81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    636 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 715
Cdd:pfam13844  161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    716 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNPDSSNTALNMPVIPMNTiAEAVIEMINR 792
Cdd:pfam13844  241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    793 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 872
Cdd:pfam13844  320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    873 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 952
Cdd:pfam13844  400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    953 SRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMEL 1016
Cdd:pfam13844  480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 246-1027 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 585.42  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  246 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  326 HADSLNNLanikREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTL 405
Cdd:COG3914   81 LELAALLL----QALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  406 KEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDER 485
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  486 MKKLvsivaEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPPYEHPKDLKLSDGRLRVGYVSSDF 565
Cdd:COG3914  237 EELL-----AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPELPPPPNPRDPDRKLRIGYVSADF 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  566 GNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNGKAADRIHQDGIHILVNMNGYTKG 645
Cdd:COG3914  308 RRHAVGYLLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DEEAAELIRADGIDILVDLSGHTAG 385

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  646 ARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFigdhanmfphlkkkavidfks 725
Cdd:COG3914  386 NRLGVFALRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGSYL--------------------- 444

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  726 nghiydnrivlngidlkafldslpdvkivkmkCPDGGDnpdssntalNMPVIPmntiaeavieminrgqiqitingfsis 805
Cdd:COG3914  445 --------------------------------CYQPND---------RAPEVA--------------------------- 456

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  806 nglattqinnkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFP-AVGEP 884
Cdd:COG3914  457 ----------------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWARILKAVPNSVLLLKGGGlPEARE 514

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  885 NIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLG 964
Cdd:COG3914  515 RLRAAAAARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGVPVVTLAGETFASRVGASLLTALG 594

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607  965 CLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHY 1027
Cdd:COG3914  595 LPELIATSEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYRQMWQRW 657
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 190-457 1.46e-50

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 179.92  E-value: 1.46e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269
Cdd:COG2956    7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  270 YEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRL 349
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  350 YRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAfA 429
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-D 245

                        250       260
                 ....*....|....*....|....*...
gi 46909607  430 DAHSNLASIHKDSGNIPEAIASYRTALK 457
Cdd:COG2956  246 DLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 163-425 1.99e-47

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 170.68  E-value: 1.99e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  163 LGNLLKAL-----GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKE 237
Cdd:COG2956    9 LGWYFKGLnyllnGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLK 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  238 ARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYN 317
Cdd:COG2956   89 AGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALE 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  318 TALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTfADA 397
Cdd:COG2956  169 KALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDL 247

                        250       260
                 ....*....|....*....|....*...
gi 46909607  398 YSNMGNTLKEMQDVQGALQCYTRAIQIN 425
Cdd:COG2956  248 LLALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 241-500 2.32e-47

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 170.68  E-value: 2.32e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  241 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTAL 320
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  321 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSN 400
Cdd:COG2956  104 ELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLL 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  401 MGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDfPDAYCNLAHCLQivcdwt 480
Cdd:COG2956  184 LAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLE------ 256

                        250       260
                 ....*....|....*....|
gi 46909607  481 dYDERMKKLVSIVAEQLEKN 500
Cdd:COG2956  257 -RKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
286-466 8.70e-46

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 165.18  E-value: 8.70e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  286 IELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHS 365
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  366 NLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 445
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180
                 ....*....|....*....|.
gi 46909607  446 PEAIASYRTALKLKPDFPDAY 466
Cdd:COG0457  161 EEALELLEKLEAAALAALLAA 181
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-389 1.04e-45

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 166.06  E-value: 1.04e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  125 GYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 204
Cdd:COG2956   10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  205 GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR 284
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  285 AIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEfAAAH 364
Cdd:COG2956  170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLL 248

                        250       260
                 ....*....|....*....|....*
gi 46909607  365 SNLASVLQQQGKLQEALMHYKEAIR 389
Cdd:COG2956  249 LALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 59-321 3.34e-45

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 164.52  E-value: 3.34e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   59 LLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGD 138
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  139 MEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAV 218
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  219 TLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHfPDAYCN 298
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLA 250

                        250       260
                 ....*....|....*....|...
gi 46909607  299 LANALKEKGSVAEAEDCYNTALR 321
Cdd:COG2956  251 LADLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
252-458 4.40e-45

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 162.87  E-value: 4.40e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  252 LSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLN 331
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  332 NLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDV 411
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 46909607  412 QGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
218-389 5.28e-45

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 162.87  E-value: 5.28e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  218 VTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYC 297
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  298 NLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKL 377
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170
                 ....*....|..
gi 46909607  378 QEALMHYKEAIR 389
Cdd:COG0457  161 EEALELLEKLEA 172
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-389 7.26e-45

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 162.48  E-value: 7.26e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  184 IETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 263
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNI 343
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 46909607  344 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 389
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 95-355 1.57e-44

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 162.59  E-value: 1.57e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   95 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLE 174
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  175 EAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSL 254
Cdd:COG2956   94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  255 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPThADSLNNLA 334
Cdd:COG2956  174 DPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALA 252

                        250       260
                 ....*....|....*....|.
gi 46909607  335 NIKREQGNIEEAVRLYRKALE 355
Cdd:COG2956  253 DLLERKEGLEAALALLERQLR 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
150-390 1.09e-43

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 159.02  E-value: 1.09e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYI 229
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  230 NLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSV 309
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  310 AEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 389
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240


                 .
gi 46909607  390 I 390
Cdd:COG0457  241 Y 241
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
320-474 8.08e-43

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 156.71  E-value: 8.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  320 LRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYS 399
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607  400 NMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 474
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-465 9.90e-42

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 165.64  E-value: 9.90e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     22 QGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKE 101
Cdd:TIGR02917  228 AVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQ 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    102 RGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYL 181
Cdd:TIGR02917  308 LGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLA 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    182 KAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVV 261
Cdd:TIGR02917  388 KATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASL 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    262 HGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Cdd:TIGR02917  468 HNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    342 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA 421
Cdd:TIGR02917  548 NEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 46909607    422 IQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 465
Cdd:TIGR02917  628 LALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEA 671
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-289 1.90e-41

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 152.47  E-value: 1.90e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   82 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRS 161
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  162 DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 241
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  242 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 269-502 1.98e-40

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 150.65  E-value: 1.98e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  269 YYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVR 348
Cdd:COG2956   18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  349 LYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 428
Cdd:COG2956   98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607  429 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRL 502
Cdd:COG2956  178 ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL 251
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 31-460 3.60e-40

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 161.02  E-value: 3.60e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     31 EYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIE 110
Cdd:TIGR02917  305 EYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAE 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    111 HYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLycVRSDLGNLLKALGRLEEAKAcyLKAIET---- 186
Cdd:TIGR02917  385 YLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPEL--GRADLLLILSYLRSGQFDKA--LAAAKKlekk 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    187 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNV-LKEARIfDRAVAAYLRALSLSPNHAVVHGNL 265
Cdd:TIGR02917  461 QPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIdIQEGNP-DDAIQRFEKVLTIDPKNLRAILAL 539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    266 ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEE 345
Cdd:TIGR02917  540 AGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNK 619

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    346 AVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQIN 425
Cdd:TIGR02917  620 AVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQH 699

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 46909607    426 PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 460
Cdd:TIGR02917  700 PKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP 734
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-289 4.00e-37

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 140.14  E-value: 4.00e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   51 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLA 130
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  131 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLA 210
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA 163

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46909607  211 IHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:COG0457  164 LELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQ 242
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 33-450 3.72e-34

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 141.76  E-value: 3.72e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     33 QAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDR------------SAHFS------TLAIKQ-NPLLA---- 89
Cdd:TIGR02917  443 RSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKareafekalsiePDFFPaaanlaRIDIQEgNPDDAiqrf 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     90 -----------EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYC 158
Cdd:TIGR02917  523 ekvltidpknlRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPE 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    159 VRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEA 238
Cdd:TIGR02917  603 AWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAA 682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    239 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHfPDAYCNLANALKEKGSVAEAEDCYNT 318
Cdd:TIGR02917  683 KRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPS-SQNAIKLHRALLASGNTAEAVKTLEA 761

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    319 ALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQgKLQEALMHYKEAIRISPTFADAY 398
Cdd:TIGR02917  762 WLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLAPNIPAIL 840

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 46909607    399 SNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIA 450
Cdd:TIGR02917  841 DTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARK 892
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 27-471 1.65e-33

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 139.83  E-value: 1.65e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     27 LAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP--LLAEAYSNLgnVYKERGQ 104
Cdd:TIGR02917  199 KGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPnsPLAHYLKAL--VDFQKKN 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    105 LQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAI 184
Cdd:TIGR02917  277 YEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPAL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    185 ETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGnVLK----EARifdRAVAAYLRALSLSPNHAV 260
Cdd:TIGR02917  357 GLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG-ISKlsqgDPS---EAIADLETAAQLDPELGR 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    261 VHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQ 340
Cdd:TIGR02917  433 ADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQE 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    341 GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTR 420
Cdd:TIGR02917  513 GNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNE 592

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 46909607    421 AIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 471
Cdd:TIGR02917  593 AADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLAD 643
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 19-496 1.39e-31

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 133.67  E-value: 1.39e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     19 LSFQGLAELAhreyqAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNV 98
Cdd:TIGR02917  128 LALRGLAYLG-----LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     99 YKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDlycvrSDLGNLLKAL-----GRL 173
Cdd:TIGR02917  203 LLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPN-----SPLAHYLKALvdfqkKNY 277

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    174 EEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALS 253
Cdd:TIGR02917  278 EDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALG 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    254 LSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCP--THADSLN 331
Cdd:TIGR02917  358 LDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPelGRADLLL 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    332 NLANIKREQ--------------------------------GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE 379
Cdd:TIGR02917  438 ILSYLRSGQfdkalaaakklekkqpdnaslhnllgaiylgkGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDD 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    380 ALMHYKEAIRISPTFADAYsnmgNTLKEMQDVQG----ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 455
Cdd:TIGR02917  518 AIQRFEKVLTIDPKNLRAI----LALAGLYLRTGneeeAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEA 593

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 46909607    456 LKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQ 496
Cdd:TIGR02917  594 ADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDS 634
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 299-470 6.02e-31

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 123.30  E-value: 6.02e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  299 LANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQ 378
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  379 EALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Cdd:COG2956   94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                        170
                 ....*....|..
gi 46909607  459 KPDFPDAYCNLA 470
Cdd:COG2956  174 DPDCARALLLLA 185
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 327-462 1.52e-28

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 111.82  E-value: 1.52e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 406
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  407 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 462
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 81-470 3.60e-28

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 122.50  E-value: 3.60e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK-------PDFIDGYI---------------------NLAAA 132
Cdd:TIGR02917   48 ALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGypknqvlPLLARAYLlqgkfqqvldelpgktllddeGAAEL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    133 LVAAGD-------MEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 205
Cdd:TIGR02917  128 LALRGLaylglgqLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLG 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    206 EIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAvAAYLRALSLS-PNHAVVHGNLACVYYEQGLIDLAIDTYRR 284
Cdd:TIGR02917  208 NIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA-EKHADALLKKaPNSPLAHYLKALVDFQKKNYEDARETLQD 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    285 AIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
Cdd:TIGR02917  287 ALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAAL 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    365 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADA------------- 431
Cdd:TIGR02917  367 SLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRAdlllilsylrsgq 446

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    432 ---------------------HSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 470
Cdd:TIGR02917  447 fdkalaaakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLA 506
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
32-193 9.72e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.18  E-value: 9.72e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   32 YQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEH 111
Cdd:COG0457   19 RRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALED 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  112 YRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFA 191
Cdd:COG0457   99 YDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAAL 178


                 ..
gi 46909607  192 VA 193
Cdd:COG0457  179 LA 180
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 89-470 1.55e-27

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 120.57  E-value: 1.55e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
Cdd:TIGR02917   22 PEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYL 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    169 ALGRLEEAKAcYLKAIETQPN--FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVA 246
Cdd:TIGR02917  102 LQGKFQQVLD-ELPGKTLLDDegAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    247 AYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 326
Cdd:TIGR02917  181 LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 406
Cdd:TIGR02917  261 PLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQL 340

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    407 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 470
Cdd:TIGR02917  341 RLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG 404
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 265-392 1.94e-26

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 105.66  E-value: 1.94e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  265 LACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE 344
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  345 EAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 392
Cdd:COG4783   90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 162-292 3.30e-26

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 104.89  E-value: 3.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  162 DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIF 241
Cdd:COG4783    9 ALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 46909607  242 DRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHF 292
Cdd:COG4783   89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 225-360 5.15e-26

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 104.50  E-value: 5.15e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  225 LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK 304
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  305 EKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 360
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 294-428 1.98e-25

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 102.96  E-value: 1.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  294 DAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQ 373
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 46909607  374 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 428
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 17-257 1.36e-24

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 110.08  E-value: 1.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   17 RMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLG 96
Cdd:COG3914   74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLG 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   97 NVYKERGQLQEAIEHYRHALRLKPDFIDGYINlaaalvaagdmegavqayvsalqynpdlycvrsdLGNLLKALGRLEEA 176
Cdd:COG3914  154 EALRRLGRLEEAIAALRRALELDPDNAEALNN----------------------------------LGNALQDLGRLEEA 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  177 KACYLKAIETQPNFAVAWSNL------GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN---LGNVLKEARIFDRAVA- 246
Cdd:COG3914  200 IAAYRRALELDPDNADAHSNLlfalrqACDWEVYDRFEELLAALARGPSELSPFALLYLPdddPAELLALARAWAQLVAa 279

                        250
                 ....*....|.
gi 46909607  247 AYLRALSLSPN 257
Cdd:COG3914  280 AAAPELPPPPN 290
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-281 2.91e-24

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 109.79  E-value: 2.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     20 SFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVY 99
Cdd:TIGR02917  634 SALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLY 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    100 KERGQLQEAIEHYRHALRLKPDfIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAC 179
Cdd:TIGR02917  714 LRQKDYPAAIQAYRKALKRAPS-SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKH 792

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    180 YLKAIETQPNFAVAWSNLGCVFnAQGEIWLAIHHFEKAVTL---DPNFLDAYinlGNVLKEARIFDRAVAAYLRALSLSP 256
Cdd:TIGR02917  793 YQTVVKKAPDNAVVLNNLAWLY-LELKDPRALEYAERALKLapnIPAILDTL---GWLLVEKGEADRALPLLRKAVNIAP 868

                          250       260
                   ....*....|....*....|....*
gi 46909607    257 NHAVVHGNLACVYYEQGLIDLAIDT 281
Cdd:TIGR02917  869 EAAAIRYHLALALLATGRKAEARKE 893
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 89-224 4.89e-24

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 98.73  E-value: 4.89e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  169 ALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
213-389 1.88e-23

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 99.99  E-value: 1.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  213 HFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLsPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHF 292
Cdd:COG4785   28 ALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAL-PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNL----- 367
Cdd:COG4785  107 AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLylaer 186

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 46909607  368 ---------------ASVLQQQGKLQEALMHYKEAIR 389
Cdd:COG4785  187 kldpekalallledwATAYLLQGDTEEARELFKLALA 223
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
126-355 3.81e-23

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 99.22  E-value: 3.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  126 YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIE------TQPNFAVAWSNLGC 199
Cdd:COG4785    2 YALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAEridralALPDLAQLYYERGV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  200 VFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 279
Cdd:COG4785   82 AYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAI 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  280 DTYRRAIELQPHFPDAYCNLANALKEKGsvaeaedcYNTALRLCPTHADSLNNLanikreQGNIEEAVRLYRKALE 355
Cdd:COG4785  162 ADLEKALELDPNDPERALWLYLAERKLD--------PEKALALLLEDWATAYLL------QGDTEEARELFKLALA 223
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
295-498 4.07e-23

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 98.83  E-value: 4.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  295 AYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVF------PEFAAAHSNLA 368
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIdralalPDLAQLYYERG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  369 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEA 448
Cdd:COG4785   81 VAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 46909607  449 IASYRTALKLKPDFPDAYCNLAHCLQIVcdwtDYDERMKKLVSIVAEQLE 498
Cdd:COG4785  161 IADLEKALELDPNDPERALWLYLAERKL----DPEKALALLLEDWATAYL 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 278-398 7.57e-23

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 95.07  E-value: 7.57e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  278 AIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVF 357
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 46909607  358 PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAY 398
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 243-363 1.16e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 94.69  E-value: 1.16e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  243 RAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL 322
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 46909607  323 CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 363
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 191-326 1.80e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 94.49  E-value: 1.80e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  191 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYY 270
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  271 EQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 326
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 210-328 3.37e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 93.15  E-value: 3.37e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 46909607  290 PHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHAD 328
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 345-466 6.45e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 92.38  E-value: 6.45e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  345 EAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 424
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 46909607  425 NPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 466
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 24-155 8.31e-22

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 92.56  E-value: 8.31e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERG 103
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 46909607  104 QLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD 155
Cdd:COG4783   87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 311-438 9.23e-22

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 91.99  E-value: 9.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  311 EAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 390
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  391 SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 438
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
84-246 5.94e-21

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 92.67  E-value: 5.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   84 QNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL 163
Cdd:COG4785   68 ALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNR 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  164 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLgcvFNAQGEIwlaihHFEKAV-TLDPNFLDAYINLGNVLKEARIFD 242
Cdd:COG4785  148 GIALYYLGRYELAIADLEKALELDPNDPERALWL---YLAERKL-----DPEKALaLLLEDWATAYLLQGDTEEARELFK 219


                 ....
gi 46909607  243 RAVA 246
Cdd:COG4785  220 LALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 361-496 6.17e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.87  E-value: 6.17e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  361 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 440
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  441 DSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQ 496
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 57-190 6.42e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.87  E-value: 6.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   57 VLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAA 136
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 46909607  137 GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 190
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 81-191 7.64e-21

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 89.29  E-value: 7.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVR 160
Cdd:COG4235    9 ALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88

                         90       100       110
                 ....*....|....*....|....*....|.
gi 46909607  161 SDLGNLLKALGRLEEAKACYLKAIETQPNFA 191
Cdd:COG4235   89 YLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 89-487 9.65e-21

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 97.75  E-value: 9.65e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIdGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
Cdd:TIGR00990  127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYD 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    169 ALGRLEEA---------------------------KACYLKAIE----TQPNFAVAWS--NLGCVFNAQgeiwLAIHHFE 215
Cdd:TIGR00990  206 GLGKYADAlldltasciidgfrneqsaqaverllkKFAESKAKEiletKPENLPSVTFvgNYLQSFRPK----PRPAGLE 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    216 KAVTLDPNFLDAYINLGNVLKEARI---FDRAVAAYLRALS---LSPNHAVVH---GNLACVY--YEQGLIDLaidtyRR 284
Cdd:TIGR00990  282 DSNELDEETGNGQLQLGLKSPESKAdesYEEAARAFEKALDlgkLGEKEAIALnlrGTFKCLKgkHLEALADL-----SK 356

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    285 AIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
Cdd:TIGR00990  357 SIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSH 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    365 SNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDS-- 442
Cdd:TIGR00990  437 IQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLINKAla 516

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 46909607    443 -----GNIPEAIASYRTALKLKPDFPDAYCNLAhclQIVCDWTDYDERMK 487
Cdd:TIGR00990  517 lfqwkQDFIEAENLCEKALIIDPECDIAVATMA---QLLLQQGDVDEALK 563
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 22-380 5.17e-20

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 96.31  E-value: 5.17e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     22 QGLAELAHREyqaGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKE 101
Cdd:TIGR02917  537 LALAGLYLRT---GNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLA 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    102 RGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYl 181
Cdd:TIGR02917  614 AGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIA- 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    182 KAIETQ-PNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN----------------------FLDAYIN-------- 230
Cdd:TIGR02917  693 KSLQKQhPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSsqnaiklhrallasgntaeavkTLEAWLKthpndavl 772

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    231 ---LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDlAIDTYRRAIELQPHFPdaycnlanalkekg 307
Cdd:TIGR02917  773 rtaLAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPR-ALEYAERALKLAPNIP-------------- 837

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607    308 svaeaedcyntalrlcpthaDSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 380
Cdd:TIGR02917  838 --------------------AILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEA 890
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 175-296 6.09e-20

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 86.60  E-value: 6.09e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  175 EAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSL 254
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 46909607  255 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAY 296
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
268-359 7.86e-20

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 85.22  E-value: 7.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  268 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDcYNTALRLCPTHADSLNNLANIKREQGNIEEAV 347
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 46909607  348 RLYRKALEVFPE 359
Cdd:COG3063   80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 220-358 1.33e-19

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 86.55  E-value: 1.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  220 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNL 299
Cdd:COG5010   15 LLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNL 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 46909607  300 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP 358
Cdd:COG5010   95 ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 241-392 1.47e-19

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 86.55  E-value: 1.47e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  241 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTAL 320
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46909607  321 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 392
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
336-427 5.61e-19

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 82.91  E-value: 5.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  336 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMhYKEAIRISPTFADAYSNMGNTLKEMQDVQGAL 415
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 46909607  416 QCYTRAIQINPA 427
Cdd:COG3063   80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 104-256 1.38e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 83.86  E-value: 1.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  104 QLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 183
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607  184 IETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSP 256
Cdd:COG5010   81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 107-223 3.03e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.98  E-value: 3.03e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  107 EAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIET 186
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 46909607  187 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 223
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 277-426 3.20e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 82.70  E-value: 3.20e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  277 LAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356
Cdd:COG5010    4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  357 FPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 426
Cdd:COG5010   84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
370-461 3.70e-18

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 80.60  E-value: 3.70e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  370 VLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQcYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 449
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 46909607  450 ASYRTALKLKPD 461
Cdd:COG3063   80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 344-460 8.09e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 81.55  E-value: 8.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  344 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 423
Cdd:COG5010   37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 46909607  424 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 460
Cdd:COG5010  117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 166-290 9.17e-18

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 81.55  E-value: 9.17e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  166 LLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAV 245
Cdd:COG5010   29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 46909607  246 AAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 290
Cdd:COG5010  109 EYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
220-457 1.05e-17

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 83.43  E-value: 1.05e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  220 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELqPHFPDAYCNL 299
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAL-PDLAQLYYER 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  300 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE 379
Cdd:COG4785   80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46909607  380 ALMHYKEAIRISPTFADAYSNMGNTLKEmQDVQGALQCYTRAIQINpafadahsnlasiHKDSGNIPEAIASYRTALK 457
Cdd:COG4785  160 AIADLEKALELDPNDPERALWLYLAERK-LDPEKALALLLEDWATA-------------YLLQGDTEEARELFKLALA 223
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
200-290 1.96e-17

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 78.29  E-value: 1.96e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  200 VFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVaAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 279
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|.
gi 46909607  280 DTYRRAIELQP 290
Cdd:COG3063   80 AYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 70-188 3.61e-17

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 79.62  E-value: 3.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   70 RLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 46909607  150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 188
Cdd:COG5010  115 LALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 142-259 6.47e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 78.12  E-value: 6.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  142 AVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLD 221
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 46909607  222 PNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHA 259
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
98-189 1.87e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 75.59  E-value: 1.87e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   98 VYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQaYVSALQYNPDLYCVRSDLGNLLKALGRLEEAK 177
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 46909607  178 ACYLKAIETQPN 189
Cdd:COG3063   80 AYLERALELDPS 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
50-218 1.99e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.57  E-value: 1.99e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   50 QEPDNTGVLLLLSSIHFQCRRLDRS-AHFSTlAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 128
Cdd:COG4785   68 ALPDLAQLYYERGVAYDSLGDYDLAiADFDQ-ALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  129 LAAALVAAGDMEGAVQAYVSALQYNPDLyCVRSDLGNLLKALGRLEEAKACYLKAIETQpnfavawsnlgcvFNAQGEIW 208
Cdd:COG4785  147 RGIALYYLGRYELAIADLEKALELDPND-PERALWLYLAERKLDPEKALALLLEDWATA-------------YLLQGDTE 212

                        170
                 ....*....|
gi 46909607  209 LAIHHFEKAV 218
Cdd:COG4785  213 EARELFKLAL 222
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
166-257 3.66e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 74.82  E-value: 3.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  166 LLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIhHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAV 245
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 46909607  246 AAYLRALSLSPN 257
Cdd:COG3063   80 AYLERALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 266-494 4.67e-16

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 83.21  E-value: 4.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    266 ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEE 345
Cdd:TIGR02917   29 AKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQ 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    346 AVRLYRKA-LEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI 424
Cdd:TIGR02917  109 VLDELPGKtLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTA 188

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    425 NPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAhclQIVCDWTDYDERMKKLVSIVA 494
Cdd:TIGR02917  189 DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALA---TILIEAGEFEEAEKHADALLK 255
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 70-222 5.49e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 76.54  E-value: 5.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   70 RLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607  150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP 222
Cdd:COG5010   81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 379-470 5.57e-16

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 75.43  E-value: 5.57e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  379 EALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|..
gi 46909607  459 KPDFPDAYCNLA 470
Cdd:COG4235   81 DPDNPEALYLLG 92
gliding_GltE NF033758
adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a ...
 214-470 2.23e-15

adventurous gliding motility TPR repeat lipoprotein GltE; GltE (also called AglT) is a tetratricopeptide repeat protein with a lipoprotein signal peptide and a role in A-motility (adventurous gliding motility) in Myxococcus xanthus and other delta-proteobacteria.


Pssm-ID: 468174 [Multi-domain]  Cd Length: 411  Bit Score: 79.48  E-value: 2.23e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   214 FEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPnhavvhgnlacvyyeqglidlaidTYRRAIElqphfp 293
Cdd:NF033758   75 FKAALEADPNLAEAEYNLGVLAERQGKTDEAVARYKAALKKKP------------------------TLRQASE------ 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   294 daycNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA---------- 363
Cdd:NF033758  125 ----NLAVMAQNAGDVAGAVALYQDVLKRYPDDASSRARLAEIYRQTGDHDKAMELSRAALMRDPQSTTAlkvmmrsyld 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   364 ------------------------HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYT 419
Cdd:NF033758  201 rkqlamaklvalravkidqndpelHHTVGLILLQEGDKDGARLQFKRALEVRADYVPSHVELAQLALDAEDYPGAEEHLR 280

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 46909607   420 RAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 470
Cdd:NF033758  281 RILQADGKNAAAHLNLGVAYKGQGQYDKAMQEYDEAEKLDPELAAIYLNRA 331
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 294-465 2.26e-15

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 76.61  E-value: 2.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    294 DAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQ 373
Cdd:TIGR02521   32 KIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQ 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    374 QGKLQEALMHYKEAIRiSPTF---ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIA 450
Cdd:TIGR02521  112 QGKYEQAMQQFEQAIE-DPLYpqpARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARA 190

                          170
                   ....*....|....*
gi 46909607    451 SYRTALKLKPDFPDA 465
Cdd:TIGR02521  191 YLERYQQTYNQTAES 205
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 339-471 3.95e-15

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 75.84  E-value: 3.95e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    339 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 418
Cdd:TIGR02521   43 EQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQF 122

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    419 TRAIQIN--PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 471
Cdd:TIGR02521  123 EQAIEDPlyPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAE 177
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 126-290 4.14e-15

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 75.84  E-value: 4.14e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    126 YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 205
Cdd:TIGR02521   34 RVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQG 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    206 EIWLAIHHFEKAVtLDPNF---LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLI---DLAI 279
Cdd:TIGR02521  114 KYEQAMQQFEQAI-EDPLYpqpARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYkdaRAYL 192

                          170
                   ....*....|.
gi 46909607    280 DTYRRAIELQP 290
Cdd:TIGR02521  193 ERYQQTYNQTA 203
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 49-155 4.51e-15

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 72.73  E-value: 4.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   49 RQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 128
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYL 90

                         90       100
                 ....*....|....*....|....*..
gi 46909607  129 LAAALVAAGDMEGAVQAYVSALQYNPD 155
Cdd:COG4235   91 LGLAAFQQGDYAEAIAAWQKLLALLPA 117
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 24-154 1.55e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 72.30  E-value: 1.55e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERG 103
Cdd:COG5010   23 LVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG 102

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 46909607  104 QLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 154
Cdd:COG5010  103 DKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 89-260 1.86e-14

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 73.91  E-value: 1.86e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
Cdd:TIGR02521   31 AKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLC 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    169 ALGRLEEAKACYLKAIETQ--PNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVA 246
Cdd:TIGR02521  111 QQGKYEQAMQQFEQAIEDPlyPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARA 190

                          170
                   ....*....|....
gi 46909607    247 AYLRALSLSPNHAV 260
Cdd:TIGR02521  191 YLERYQQTYNQTAE 204
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 83-393 4.52e-14

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 76.56  E-value: 4.52e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     83 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYN---PDLYCV 159
Cdd:TIGR00990  325 KLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNsedPDIYYH 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    160 RSDLgNLLKAlgrleeakacylkaietqpNFAVAWSNlgcvfnaqgeiwlaihhFEKAVTLDPNFLDAYINLGnvlkear 239
Cdd:TIGR00990  405 RAQL-HFIKG-------------------EFAQAGKD-----------------YQKSIDLDPDFIFSHIQLG------- 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    240 ifdravaaylralslspnhavvhgnlaCVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTA 319
Cdd:TIGR00990  441 ---------------------------VTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTA 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    320 LRL-------CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 392
Cdd:TIGR00990  494 IELeketkpmYMNVLPLINKALALFQWKQDFIEAENLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAELAR 573


                   .
gi 46909607    393 T 393
Cdd:TIGR00990  574 T 574
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
64-157 5.73e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 68.66  E-value: 5.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   64 IHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEhYRHALRLKPDFIDGYINLAAALVAAGDMEGAV 143
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....
gi 46909607  144 QAYVSALQYNPDLY 157
Cdd:COG3063   80 AYLERALELDPSAL 93
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
132-226 1.08e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 67.89  E-value: 1.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  132 ALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAcYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAI 211
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....*
gi 46909607  212 HHFEKAVTLDPNFLD 226
Cdd:COG3063   80 AYLERALELDPSALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 348-473 2.68e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 68.45  E-value: 2.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  348 RLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 427
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 46909607  428 FADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 473
Cdd:COG5010   87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 293-392 7.97e-13

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 69.50  E-value: 7.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ 372
Cdd:NF033920  156 PLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALA 235

                          90       100
                  ....*....|....*....|
gi 46909607   373 QQGKLQEALMHYKEAIRISP 392
Cdd:NF033920  236 AQGCTAQARAAAECALALAP 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
32-121 8.27e-13

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 65.19  E-value: 8.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   32 YQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTlAIKQNPLLAEAYSNLGNVYKERGQLQEAIEH 111
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 46909607  112 YRHALRLKPD 121
Cdd:COG3063   82 LERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 22-136 2.83e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.03  E-value: 2.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   22 QGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKE 101
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 46909607  102 RGQLQEAIEHYRHALRLKPDFIDGYInLAAALVAA 136
Cdd:COG4235   98 QGDYAEAIAAWQKLLALLPADAPARL-LEASIAEA 131
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
407-473 3.27e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 63.65  E-value: 3.27e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607  407 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAsYRTALKLKPDFPDAYCNLAHCL 473
Cdd:COG3063    4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELL 69
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 167-357 5.11e-12

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 68.04  E-value: 5.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  167 LKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN-FLDAYINLGNVL--KEA-RIFD 242
Cdd:cd24142   10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLGQLSggEEAlQYYE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  243 RAVAAYLRALslspnhavvhgnlacvyyeQGLIDLAIDTYRRAIELQPHFPDAYCNLA-----NALKEKGSVAEAEDCYN 317
Cdd:cd24142   90 KGIEILEEEL-------------------QALQAASAEAEEEAEELKRKLSSALCALAeiymtDLCDEPDAEQRCEELIT 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 46909607  318 TALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVF 357
Cdd:cd24142  151 KALELDPTNPEALQTLASLRISQQRPDEAKEALRRSLELW 190
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 174-464 6.96e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 69.63  E-value: 6.96e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    174 EEAKACYLKAI---ETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 250
Cdd:TIGR00990  311 EEAARAFEKALdlgKLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDK 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    251 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL 330
Cdd:TIGR00990  391 ALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVY 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    331 NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKE-------AIRISPTFADAYSNMGN 403
Cdd:TIGR00990  471 NYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLINKALALFQWKQDFIEaenlcekALIIDPECDIAVATMAQ 550

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    404 TLKEMQDVQGALQCYTRAiqinpafadahsnlASIHKDSGNIPEAIA---SYRTALKLKPDFPD 464
Cdd:TIGR00990  551 LLLQQGDVDEALKLFERA--------------AELARTEGELVQAISyaeATRTQIQVQEDYPV 600
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 24-122 6.97e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 6.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERG 103
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         90
                 ....*....|....*....
gi 46909607  104 QLQEAIEHYRHALRLKPDF 122
Cdd:COG4783  121 RPDEAIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
327-390 9.24e-12

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 61.63  E-value: 9.24e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVF--------PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRI 390
Cdd:pfam13424    3 ATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 269-485 1.24e-11

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 66.88  E-value: 1.24e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  269 YYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH-ADSLNNLANIkrEQGniEEAV 347
Cdd:cd24142   10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQL--SGG--EEAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  348 RLYRKALEVfpefaaahsnLASVLQQQGKLQEALMHYKEAIRisPTFADAYSNMGntlkE--MQDV-------QGALQCY 418
Cdd:cd24142   86 QYYEKGIEI----------LEEELQALQAASAEAEEEAEELK--RKLSSALCALA----EiyMTDLcdepdaeQRCEELI 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46909607  419 TRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL-KPDFPDAYCNLAHCLQIVCDWTDYDER 485
Cdd:cd24142  150 TKALELDPTNPEALQTLASLRISQQRPDEAKEALRRSLELwKDLKEEDEEEAEEDEAEEEDVPSYEFR 217
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 23-393 7.48e-11

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 66.65  E-value: 7.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    23 GLAELAHREyqaGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQ--------NPLLAEAYSN 94
Cdd:PRK11447  390 GLGDVAMAR---KDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQSPEKALAFIASLSASQrrsiddieRSLQNDRLAQ 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    95 LGNVYKERGQLQEAIEHYRHALRLKPDfiDGYIN--LAAALVAAGDMEGAVQAYVSALQYNPdlycvrsdlgnllkalGR 172
Cdd:PRK11447  467 QAEALENQGKWAQAAELQRQRLALDPG--SVWLTyrLAQDLRQAGQRSQADALMRRLAQQKP----------------ND 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   173 LEE--AKACYLKAIEtQPNFAVAwsNLGCVFNAQgeiWLA-IHHFEKAVTLDpNFLDAYINLGNVLKEArifdrAVAAYL 249
Cdd:PRK11447  529 PEQvyAYGLYLSGSD-RDRAALA--HLNTLPRAQ---WNSnIQELAQRLQSD-QVLETANRLRDSGKEA-----EAEALL 596

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   250 RALSLSPNHAVVhgnLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEdcynTALRLCPTHA-D 328
Cdd:PRK11447  597 RQQPPSTRIDLT---LADWAQQRGDYAAARAAYQRVLTREPGNADARLGLIEVDIAQGDLAAAR----AQLAKLPATAnD 669

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607   329 SLN---NLANIKREQGNIEEAVRLYR------KALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI---RISPT 393
Cdd:PRK11447  670 SLNtqrRVALAWAALGDTAAAQRTFNrlipqaKSQPPSMESALVLRDAARFEAQTGQPQQALETYKDAMvasGITPT 746
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 101-462 8.00e-11

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 66.65  E-value: 8.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   101 ERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCvRSDLGNLLKAlGRleeakacY 180
Cdd:PRK11447  281 DSGQGGKAIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSSN-RDKWESLLKV-NR-------Y 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   181 LKAIEtQPNFAVAWSNLGcvfnaqgeiwLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSP-NHA 259
Cdd:PRK11447  352 WLLIQ-QGDAALKANNLA----------QAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPgNTN 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   260 VVHGnLACVYYEQG-------LIDL------AIDTYRRAIELqphfpDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 326
Cdd:PRK11447  421 AVRG-LANLYRQQSpekalafIASLsasqrrSIDDIERSLQN-----DRLAQQAEALENQGKWAQAAELQRQRLALDPGS 494

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFP-------------------EFAAAHSN--------------------- 366
Cdd:PRK11447  495 VWLTYRLAQDLRQAGQRSQADALMRRLAQQKPndpeqvyayglylsgsdrdRAALAHLNtlpraqwnsniqelaqrlqsd 574

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   367 ----LASVLQQQGKLQEA--LMHYKEA-IRISPTFADAYSNMGntlkemqDVQGALQCYTRAIQINPAFADAHSNLASIH 439
Cdd:PRK11447  575 qvleTANRLRDSGKEAEAeaLLRQQPPsTRIDLTLADWAQQRG-------DYAAARAAYQRVLTREPGNADARLGLIEVD 647

                         410       420
                  ....*....|....*....|...
gi 46909607   440 KDSGNIPEAiasyRTALKLKPDF 462
Cdd:PRK11447  648 IAQGDLAAA----RAQLAKLPAT 666
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 226-391 1.01e-10

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 64.19  E-value: 1.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  226 DAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-HFPDAYCNLANALK 304
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPdGGYEKYLYLGQLSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  305 EKgsvaEAEDCYNTALRLCPTHADSLNNLAniKREQGNIEEAVR-----------LY------------------RKALE 355
Cdd:cd24142   81 GE----EALQYYEKGIEILEEELQALQAAS--AEAEEEAEELKRklssalcalaeIYmtdlcdepdaeqrceeliTKALE 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 46909607  356 VFPEFAAAHSNLASVLQQQGKLQEAlmhyKEAIRIS 391
Cdd:cd24142  155 LDPTNPEALQTLASLRISQQRPDEA----KEALRRS 186
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 328-470 1.77e-10

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 63.42  E-value: 1.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  328 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT-FADAYSNMGntlk 406
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLG---- 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  407 emQDVQG--ALQCYTRAIQInpafadAHSNLASIHKDSGNIPEAIAsyrtalKLKPDFPDAYCNLA 470
Cdd:cd24142   77 --QLSGGeeALQYYEKGIEI------LEEELQALQAASAEAEEEAE------ELKRKLSSALCALA 128
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 8-381 5.56e-10

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 63.40  E-value: 5.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     8 VADSTEPTKRMLsfqgLAELAHREYQAGDFEAAERHC---MQLWRQ--EPDNTGVLLL---LSSIHFQ------CRRLDR 73
Cdd:NF040586  383 ALESDDPEVRRL----LLDQVRYLYLRGDYESARDLAeraLERWRErlGPDDRQTLRLrfhLANALRSlgryeeARELDE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    74 SA-------------HFSTLAikqnpllaeAYSNLGNVYKERGQLQEAIEHYRHALR-----LKPDfiDGYI-----NLA 130
Cdd:NF040586  459 DTlerqrrvlglgedHPHTLM---------TAGGLGADLRALGRFREALELDEETLErhrrvFGED--HPRTlraanNLA 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   131 AALVAAGDmegavqaYVSALQYNPDLYCVRSDLGNllkalgrleeakacylkaiETQPNFAVAWSNLGCVFNAQGEiwla 210
Cdd:NF040586  528 VSLRLLGD-------YREALELDREVLRRRRRVLG-------------------PDHPRTLLSANNLARDLRELGR---- 577

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   211 ihhFEKAVTLdpnfldayinlgnvLKEARifdravaAYLRALSLSPNHAVVHG---NLA-----CVYYEQGLiDLAIDTY 282
Cdd:NF040586  578 ---YAEALDL--------------LEEAL-------ERYREVLGGPDHPDTLRaakSLAvalrrAGRLEEAL-ELAEDTY 632

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   283 RRAIELQ-PHFPD---AYCNLANALKEKG----SVAEAEDCYNT-ALRLCPTHADSL---NNLANIKREQGNIEEAVRLY 350
Cdd:NF040586  633 ERYRRRFgPDHPDtlaAALSLANDLRALGdadeARELAREVLDRyRRVLGEDHPFTLacrNNLAVLLRALGDPEEARELA 712

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 46909607   351 RKALEVFPE----------FAAAhsNLASVLQQQGKLQEAL 381
Cdd:NF040586  713 EAALEGLRErlgpdhpytlAAAV--NLANDLAALGDLDAAL 751
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 269-363 9.17e-10

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 56.92  E-value: 9.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  269 YYEQGLIDLAIDTYRRAIELQP---HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH---ADSLNNLANIKREQGN 342
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLKRYPnspLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGD 82

                         90       100
                 ....*....|....*....|.
gi 46909607  343 IEEAVRLYRKALEVFPEFAAA 363
Cdd:COG1729   83 YDKARATLEELIKKYPDSEAA 103
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 81-154 1.06e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 60.26  E-value: 1.06e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 154
Cdd:NF033920  182 ATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR_12 pfam13424
Tetratricopeptide repeat;
295-359 1.60e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 55.09  E-value: 1.60e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607    295 AYCNLANALKEKGSVAEAEDCYNTALRLC-----PTH---ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgPDHpltATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
24-178 1.71e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 59.64  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERG 103
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607  104 QLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKA 178
Cdd:COG0457  159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 414-473 1.64e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.24  E-value: 1.64e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  414 ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 473
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL 61
TPR_1 pfam00515
Tetratricopeptide repeat;
89-122 1.78e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 50.88  E-value: 1.78e-08
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDF 122
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 24-223 2.04e-08

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 57.23  E-value: 2.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAhreYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQC----------RRLDRSAHFSTLAIKQnpLLAEAYS 93
Cdd:COG3071   91 RAELL---LDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLgdweellellPALRKHKALSAEEAQA--LERRAYL 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   94 NLgnvYKERGQLQEAIEHYRHAL----RLKPDFIDGYinlAAALVAAGDMEGAVQAYVSALQYNPD-----LY--CVRSD 162
Cdd:COG3071  166 GL---LRQAARDAEALKALWKALpraeRRDPELAAAY---ARALIALGDHDEAERLLREALKRQWDprlvrLYgrLQGGD 239

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  163 LGNLLK-----------------ALGRL-------EEAKACYLKAIETQPNfAVAWSNLGCVFNAQGEIWLAIHHFEKAV 218
Cdd:COG3071  240 PAKQLKraekwlkkhpndpdlllALGRLclrnqlwGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKAL 318


                 ....*
gi 46909607  219 TLDPN 223
Cdd:COG3071  319 ALALG 323
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 339-423 2.22e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 53.07  E-value: 2.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  339 EQGNIEEAVRLYRKALEVFP--EFAA-AHSNLASVLQQQGKLQEALMHYKEAIRI---SPTFADAYSNMGNTLKEMQDVQ 412
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPnsPLAPdALYWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|.
gi 46909607  413 GALQCYTRAIQ 423
Cdd:COG1729   85 KARATLEELIK 95
TPR_12 pfam13424
Tetratricopeptide repeat;
359-427 2.53e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 52.00  E-value: 2.53e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607    359 EFAAAHSNLASVLQQQGKLQEALMHYKEAIRI--------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA 427
Cdd:pfam13424    1 DVATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_11 pfam13414
TPR repeat;
96-137 2.81e-08

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 50.55  E-value: 2.81e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607     96 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAG 137
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_11 pfam13414
TPR repeat;
268-307 2.98e-08

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 50.55  E-value: 2.98e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 46909607    268 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKG 307
Cdd:pfam13414    3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 302-392 3.33e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 52.69  E-value: 3.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  302 ALKEKGSVAEAEDCYNTALRLCPTH---ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE---FAAAHSNLASVLQQQG 375
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELG 81

                         90
                 ....*....|....*..
gi 46909607  376 KLQEALMHYKEAIRISP 392
Cdd:COG1729   82 DYDKARATLEELIKKYP 98
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 89-122 7.11e-08

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 49.37  E-value: 7.11e-08
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607      89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDF 122
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 203-381 1.04e-07

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 55.01  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    203 AQGEIWLAIHHFEKAVTLDP--NFLD---AYINLG--NVLKEARifDRAVAAYLRALSLSPNHAVVHGN------LACVY 269
Cdd:pfam17874   13 SKGDAERALELAEQALALLPedDLLArglATFVLGeaYLCLGDL--DAALQAMREAEALARRADSPHVTlwallqQGEIL 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    270 YEQGLIDLAIDTYRRAIELQP-----HFP---DAYCNLANALKEKGSVAEAEDCYNTALRLC---PTHA--DSLNNLANI 336
Cdd:pfam17874   91 RAQGRLHQALETYQQALQLARdhglqHLPlhgFLLVGLADLLYEWNDLEEAEQHAQQGIQLGrqwEPDAavDAYVLLARI 170

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 46909607    337 KREQGNIEEAVRLYRKALEV---FPEFAAAHSNLASV----LQQQGKLQEAL 381
Cdd:pfam17874  171 ALAQGELEEALTLLRRAELLarqSFFHVDWLANAERVrvrlWLARGDLRAAV 222
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 266-358 2.28e-07

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 53.32  E-value: 2.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   266 ACVYYEQ-GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE 344
Cdd:NF033920  162 AAQDLEQtGQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTA 241

                          90
                  ....*....|....
gi 46909607   345 EAVRLYRKALEVFP 358
Cdd:NF033920  242 QARAAAECALALAP 255
TPR_11 pfam13414
TPR repeat;
334-375 3.28e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 47.47  E-value: 3.28e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607    334 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQG 375
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 332-392 3.29e-07

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 48.49  E-value: 3.29e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    332 NLANIKREQGNIEEAVRLYRKALEVF---PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 392
Cdd:pfam13432    2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
TPR_11 pfam13414
TPR repeat;
373-409 5.63e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 47.08  E-value: 5.63e-07
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 46909607    373 QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQ 409
Cdd:pfam13414    6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_11 pfam13414
TPR repeat;
438-471 6.09e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 46.70  E-value: 6.09e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    438 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 471
Cdd:pfam13414    3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGL 36
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 373-465 8.62e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 48.45  E-value: 8.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  373 QQGKLQEALMHYKEAIRI---SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIP 446
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYD 84

                         90
                 ....*....|....*....
gi 46909607  447 EAIASYRTALKLKPDFPDA 465
Cdd:COG1729   85 KARATLEELIKKYPDSEAA 103
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 89-121 8.70e-07

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 45.98  E-value: 8.70e-07
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPD 121
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
87-151 1.08e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 1.08e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607     87 LLAEAYSNLGNVYKERGQLQEAIEHYRHALRL--------KPDFIDGYINLAAALVAAGDMEGAVQAYVSALQ 151
Cdd:pfam13424    1 DVATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 101-193 1.37e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 48.06  E-value: 1.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  101 ERGQLQEAIEHYRHALRLKPD---FIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD-------LYcvrsDLGNLLKAL 170
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkapdaLL----KLGLSYLEL 80

                         90       100
                 ....*....|....*....|...
gi 46909607  171 GRLEEAKACYLKAIETQPNFAVA 193
Cdd:COG1729   81 GDYDKARATLEELIKKYPDSEAA 103
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 28-288 3.35e-06

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 50.39  E-value: 3.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     28 AHREYQAGDFEAAERHCMQ-LWRQEPDNTGVLLLLSSIH---FQCR-RLDRS-AHFS---TLAIKQNPLLAEAYS--NLG 96
Cdd:pfam17874    8 AQLAISKGDAERALELAEQaLALLPEDDLLARGLATFVLgeaYLCLgDLDAAlQAMReaeALARRADSPHVTLWAllQQG 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     97 NVYKERGQLQEAIEHYRHALRLKPD------FIDG--YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLK 168
Cdd:pfam17874   88 EILRAQGRLHQALETYQQALQLARDhglqhlPLHGflLVGLADLLYEWNDLEEAEQHAQQGIQLGRQWEPDAAVDAYVLL 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    169 -----ALGRLEEAKAcYLKAIE---TQPNFAVAWsnLGCVFNAQGEIWLA----------IHHFEKAVTLDPNFLDA-YI 229
Cdd:pfam17874  168 arialAQGELEEALT-LLRRAEllaRQSFFHVDW--LANAERVRVRLWLArgdlraavrwLRAAEPPSDADNHFLEReLR 244

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    230 NLGNVLKEARIFDRAVAAYLRALSLS-PNHAVVHGN-----LACVYYEQGLIDLAIDTYRRAIEL 288
Cdd:pfam17874  245 NLARVLLALGRFDDALSLLERLQNLAeQLGRVRSLIenlilQALALLALGRPDEALQALLDALSL 309
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 237-508 3.85e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 51.07  E-value: 3.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   237 EARIFDRAVAAYLRALsLSPNHA---VVHGNLACVY-----YEQGLiDLAIDTYRRAIELQPhfPD------AYCNLANA 302
Cdd:NF040586  496 EALELDEETLERHRRV-FGEDHPrtlRAANNLAVSLrllgdYREAL-ELDREVLRRRRRVLG--PDhprtllSANNLARD 571

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   303 LKEKGSVAEAEDCYNTALRLC------PTHADSLN---NLANIKREQGNIEEAVRL----YRKALEVF----PEFAAAHS 365
Cdd:NF040586  572 LRELGRYAEALDLLEEALERYrevlggPDHPDTLRaakSLAVALRRAGRLEEALELaedtYERYRRRFgpdhPDTLAAAL 651

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   366 NLASVLQQQGKLQEALMHYKEAIRISP---------TFAdAYSNMGNTLKEMQDVQGALQCYTRAI-QINPAFADAH--- 432
Cdd:NF040586  652 SLANDLRALGDADEARELAREVLDRYRrvlgedhpfTLA-CRNNLAVLLRALGDPEEARELAEAALeGLRERLGPDHpyt 730

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   433 ----SNLASIHKDSGNIPEAIAS---------YRTALKLKPDFPD---AYCNLAHCLQIvcdwTDYDERMKKLVSIVAEQ 496
Cdd:NF040586  731 laaaVNLANDLAALGDLDAALGEealerlrrlLGEDLRAGPDHPDtlaCAANLALDLRA----TGRTEEAEELRADTLAR 806

                         330
                  ....*....|..
gi 46909607   497 LEKnRLPSVHPH 508
Cdd:NF040586  807 LRR-VLGPDHPD 817
TPR_11 pfam13414
TPR repeat;
164-205 4.33e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 44.38  E-value: 4.33e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607    164 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 205
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
92-190 5.03e-06

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 49.11  E-value: 5.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   92 YSNLGNVYKERGQLQEAIEHYRHAL-RLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYcvRSD----LGNL 166
Cdd:COG4700   92 RVRLADALLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFK--SSDahllYARA 169

                         90       100
                 ....*....|....*....|....
gi 46909607  167 LKALGRLEEAKACYLKAIETQPNF 190
Cdd:COG4700  170 LEALGDLEAAEAELEALARRYSGP 193
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 84-155 5.34e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.52  E-value: 5.34e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607   84 QNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI---DGYINLAAALVAAGDMEGAVQAYVSALQYNPD 155
Cdd:COG1729   25 NSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 210-464 5.67e-06

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 50.47  E-value: 5.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNH-----------------AVVHGNLAcvyYEQ 272
Cdd:PRK11447  288 AIPELQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALALDPHSsnrdkwesllkvnrywlLIQQGDAA---LKA 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   273 GLIDLAIDTYRRAIELQPHfpDAYC--NLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGnieeavrly 350
Cdd:PRK11447  365 NNLAQAERLYQQARQVDNT--DSYAvlGLGDVAMARKDYAAAERYYQQALRMDPGNTNAVRGLANLYRQQS--------- 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   351 rkalevfPEFAAAHSNLASVLQQQ--GKLQEALMHykeairisptfaDAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 428
Cdd:PRK11447  434 -------PEKALAFIASLSASQRRsiDDIERSLQN------------DRLAQQAEALENQGKWAQAAELQRQRLALDPGS 494

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 46909607   429 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPD 464
Cdd:PRK11447  495 VWLTYRLAQDLRQAGQRSQADALMRRLAQQKPNDPE 530
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 34-372 6.21e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 50.30  E-value: 6.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    34 AGDFEAAERHCMQLWRQEpdntgvllllssihfqcRRLDRSAHFSTLAikqnpllaeAYSNLGNVYKERGQLQEAIEHYR 113
Cdd:NF040586  533 LGDYREALELDREVLRRR-----------------RRVLGPDHPRTLL---------SANNLARDLRELGRYAEALDLLE 586

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   114 HALR------LKPDFIDGYI---NLAAALVAAGDMEGA-------VQAYVSALQ-YNPDLYCVRSDLGNLLKALGRLEEA 176
Cdd:NF040586  587 EALEryrevlGGPDHPDTLRaakSLAVALRRAGRLEEAlelaedtYERYRRRFGpDHPDTLAAALSLANDLRALGDADEA 666

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   177 kacyLKAIETqpnfavawsnlgcvfnaqgeiwlAIHHFEKAVTLD-PNFLDAYINLGNVLK------EARIFDRAVAAYL 249
Cdd:NF040586  667 ----RELARE-----------------------VLDRYRRVLGEDhPFTLACRNNLAVLLRalgdpeEARELAEAALEGL 719

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   250 RAlSLSPNH------AVvhgNLACVYYEQGLIDLAIDTyrraielqphfpdaycnlanalkekGSVAEAEDCYNTALRLC 323
Cdd:NF040586  720 RE-RLGPDHpytlaaAV---NLANDLAALGDLDAALGE-------------------------EALERLRRLLGEDLRAG 770

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 46909607   324 PTHADSL---NNLANIKREQGNIEEAVRLYRKALEVFPE-FAAAHSNLASVLQ 372
Cdd:NF040586  771 PDHPDTLacaANLALDLRATGRTEEAEELRADTLARLRRvLGPDHPDTVAARE 823
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 307-406 8.87e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 47.36  E-value: 8.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   307 GSVAEAEDCYNTALRLCPTHAD---SLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVL-------QQQGK 376
Cdd:PRK02603   49 GEYAEALENYEEALKLEEDPNDrsyILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGD 128

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 46909607   377 LQEALMHY-------KEAIRISPtfaDAYSNMGNTLK 406
Cdd:PRK02603  129 QDEAEALFdkaaeywKQAIRLAP---NNYIEAQNWLK 162
TPR_1 pfam00515
Tetratricopeptide repeat;
395-426 9.07e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 43.18  E-value: 9.07e-06
                           10        20        30
                   ....*....|....*....|....*....|..
gi 46909607    395 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 426
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
TPR_11 pfam13414
TPR repeat;
402-443 1.06e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 43.23  E-value: 1.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607    402 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSG 443
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_19 pfam14559
Tetratricopeptide repeat;
136-195 1.50e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.73  E-value: 1.50e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    136 AGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWS 195
Cdd:pfam14559    1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TPR_1 pfam00515
Tetratricopeptide repeat;
191-224 1.57e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 1.57e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    191 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
327-360 1.57e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.79  E-value: 1.57e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 360
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 204-295 1.66e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 1.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  204 QGEIWLAIHHFEKAVTLDPN---FLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVV---HGNLACVYYEQGLIDL 277
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDK 85

                         90
                 ....*....|....*...
gi 46909607  278 AIDTYRRAIELQPHFPDA 295
Cdd:COG1729   86 ARATLEELIKKYPDSEAA 103
TPR_10 pfam13374
Tetratricopeptide repeat;
327-356 1.89e-05

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 42.49  E-value: 1.89e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEV 356
Cdd:pfam13374    2 ASSLNNLANALRAQGRYDEAEELLEEALAI 31
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 327-360 2.05e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.43  E-value: 2.05e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 360
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
COG3899 COG3899
Predicted ATPase [General function prediction only];
338-465 2.11e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 48.70  E-value: 2.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  338 REQGNIEEAVRLYRKALEVFPEF------AAAHSNLASVLQQQGKLQEALMHYKEAIRI-------------SPTFADAY 398
Cdd:COG3899  716 LARGAYAEALRYLERALELLPPDpeeeyrLALLLELAEALYLAGRFEEAEALLERALAAralaalaalrhgnPPASARAY 795

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 46909607  399 SNMGNTLkeMQDVQGALQCYTRAIQINPAF------ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 465
Cdd:COG3899  796 ANLGLLL--LGDYEEAYEFGELALALAERLgdrrleARALFNLGFILHWLGPLREALELLREALEAGLETGDA 866
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 163-423 2.12e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 47.60  E-value: 2.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  163 LGNLLKAL-----GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYinlgnVLKE 237
Cdd:COG3071   17 LAALLEGLlalaeGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAV-----LLTR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  238 ARI------FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR--------AIELQPHFPDAYCNL---- 299
Cdd:COG3071   92 AELlldqgqAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPAlrkhkalsAEEAQALERRAYLGLlrqa 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  300 ----------------------------ANALKEKGSVAEAEDCYNTALRLCPtHADSLNNLANIkrEQGNIEEAVRLYR 351
Cdd:COG3071  172 ardaealkalwkalpraerrdpelaaayARALIALGDHDEAERLLREALKRQW-DPRLVRLYGRL--QGGDPAKQLKRAE 248

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46909607  352 KALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTfADAYSNMGNTLKEMQDVQGALQCYTRAIQ 423
Cdd:COG3071  249 KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALA 319
TPR_12 pfam13424
Tetratricopeptide repeat;
227-288 2.17e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 2.17e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    227 AYINLGNVLKEARIFDRAVAAYLRALSL--------SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
COG3899 COG3899
Predicted ATPase [General function prediction only];
88-323 2.31e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 48.70  E-value: 2.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   88 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRS 161
Cdd:COG3899  704 AARLLLRAARRALARGAYAEALRYLERALELLPPDPEEeyrlalLLELAEALYLAGRFEEAEALLERALAARALAALAAL 783

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  162 DLGNLLKA-----------LGRLEEAKACYLKAIE------TQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224
Cdd:COG3899  784 RHGNPPASarayanlglllLGDYEEAYEFGELALAlaerlgDRRLEARALFNLGFILHWLGPLREALELLREALEAGLET 863

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  225 LDAyinLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK 304
Cdd:COG3899  864 GDA---ALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAA 940

                        250
                 ....*....|....*....
gi 46909607  305 EKGSVAEAEDCYNTALRLC 323
Cdd:COG3899  941 AAAALAAAAAAAALAAALA 959
COG3899 COG3899
Predicted ATPase [General function prediction only];
243-436 2.37e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 48.70  E-value: 2.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  243 RAVAAYLRALSLSPNHA-----VVHGNLAcvyyeqGLIDLAIDTYRRAielqphfpdaycnlANALKEKGSVAEAEDCYN 317
Cdd:COG3899  670 RRIARALEARGPEPLEErlfelAHHLNRA------GERDRAARLLLRA--------------ARRALARGAYAEALRYLE 729

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  318 TALRLCP------THADSLNNLANIKREQGNIEEAVRLYRKALEV-------------FPEFAAAHSNLASVLqqQGKLQ 378
Cdd:COG3899  730 RALELLPpdpeeeYRLALLLELAEALYLAGRFEEAEALLERALAAralaalaalrhgnPPASARAYANLGLLL--LGDYE 807

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607  379 EALMHYKEAIRISPTF------ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLA 436
Cdd:COG3899  808 EAYEFGELALALAERLgdrrleARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALL 871
TPR_1 pfam00515
Tetratricopeptide repeat;
361-394 2.64e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.02  E-value: 2.64e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    361 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 394
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 87-288 2.66e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 47.24  E-value: 2.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   87 LLAEAysnlgNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD------LYcvr 160
Cdd:cd24142    3 LLEKA-----EELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDggyekyLY--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  161 sdLGNLLKAlgrlEEAKACYLKAIE-------TQPNFAVAWSNLGCVFNAQ--------GEIWLAIHHFEKavtldpnfl 225
Cdd:cd24142   75 --LGQLSGG----EEALQYYEKGIEileeelqALQAASAEAEEEAEELKRKlssalcalAEIYMTDLCDEP--------- 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607  226 DAyinlgnvlkEARifdraVAAYL-RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Cdd:cd24142  140 DA---------EQR-----CEELItKALELDPTNPEALQTLASLRISQQRPDEAKEALRRSLEL 189
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 210-426 2.68e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 47.88  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   210 AIHHFEKAVTLDPNFLDAYINLGN-------------------------------VLKE-------ARIFDRAVAAYLRa 251
Cdd:PRK11788   54 AIDLFIEMLKVDPETVELHLALGNlfrrrgevdrairihqnllsrpdltreqrllALQElgqdylkAGLLDRAEELFLQ- 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   252 LSLSPNHAVVhgnlAcvyyEQGLIDL---------AIDTYRRAIELQP--------HFpdaYCNLANALKEKGSVAEAED 314
Cdd:PRK11788  133 LVDEGDFAEG----A----LQQLLEIyqqekdwqkAIDVAERLEKLGGdslrveiaHF---YCELAQQALARGDLDAARA 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   315 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAA-AHSNLASVLQQQGKLQEALMHYKEAIRISPt 393
Cdd:PRK11788  202 LLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEYLSeVLPKLMECYQALGDEAEGLEFLRRALEEYP- 280

                         250       260       270
                  ....*....|....*....|....*....|...
gi 46909607   394 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 426
Cdd:PRK11788  281 GADLLLALAQLLEEQEGPEAAQALLREQLRRHP 313
TPR_12 pfam13424
Tetratricopeptide repeat;
24-121 2.74e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     24 LAELAHREYQAGDFEAAERH---CMQLWRQEPDntgvllllssihfqcrrldrsahfstlaiKQNPLLAEAYSNLGNVYK 100
Cdd:pfam13424    6 LNNLAAVLRRLGRYDEALELlekALEIARRLLG-----------------------------PDHPLTATTLLNLGRLYL 56

                           90       100
                   ....*....|....*....|.
gi 46909607    101 ERGQLQEAIEHYRHALRLKPD 121
Cdd:pfam13424   57 ELGRYEEALELLERALALAEK 77
TPR_1 pfam00515
Tetratricopeptide repeat;
259-292 2.97e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 2.97e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    259 AVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHF 292
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 103-236 3.03e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 45.43  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   103 GQLQEAIEHYRHALRLKPDFID-GYI--NLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKAc 179
Cdd:PRK02603   49 GEYAEALENYEEALKLEEDPNDrSYIlyNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKAEEAG- 127

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607   180 ylkaietQPNFAVAWsnlgcvFNAQGEIWlaihhfEKAVTLDPNfldAYINLGNVLK 236
Cdd:PRK02603  128 -------DQDEAEAL------FDKAAEYW------KQAIRLAPN---NYIEAQNWLK 162
TPR_1 pfam00515
Tetratricopeptide repeat;
293-326 3.25e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 3.25e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 326
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_8 pfam13181
Tetratricopeptide repeat;
89-121 3.27e-05

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 41.61  E-value: 3.27e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607     89 AEAYSNLGNVYKERGQLQEAIEHYRHALRLKPD 121
Cdd:pfam13181    1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 409-463 3.64e-05

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 47.99  E-value: 3.64e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 46909607   409 QDVQGALQCYTRAIQINPAfADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 463
Cdd:PRK09782  590 GQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLRAALELEPNNS 643
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
298-410 3.78e-05

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 46.41  E-value: 3.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  298 NLANALKEKGSVAEAEDCYNTAL-RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF--AAAHSNLASVLQQQ 374
Cdd:COG4700   94 RLADALLELGRYDEAIELYEEALtGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLLYARALEAL 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 46909607  375 GKLQEALMHYKEAIRISPTF------ADAYSNMGNT------LKEMQD 410
Cdd:COG4700  174 GDLEAAEAELEALARRYSGPearyryAKFLARQGRTaeakelLEEILD 221
TPR_12 pfam13424
Tetratricopeptide repeat;
155-223 4.02e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 42.76  E-value: 4.02e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607    155 DLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ--------PNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 223
Cdd:pfam13424    1 DVATALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 259-292 4.72e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.28  E-value: 4.72e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     259 AVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHF 292
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 191-224 4.87e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.28  E-value: 4.87e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     191 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 23-389 5.03e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 46.44  E-value: 5.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   23 GLAELAH--REYQAGDFEAAERHCMQLWRQEpDNTGVLLLLSSihfqcrrldRSAHfstlaikqnpllaeaysnlgnvyk 100
Cdd:COG3071   16 LLAALLEglLALAEGRYARAEKLLSKAAEHS-EAPLLAYLLAA---------RAAQ------------------------ 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  101 ERGQLQEAIEHYRHALRLKPDFidgyiNLAAALVAA------GDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLE 174
Cdd:COG3071   62 ALGDYERRDEYLAQALELAPEA-----ELAVLLTRAellldqGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWE 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  175 EAKAcYLKAIETQPNFAVAWSnlgcvfnAQGEIWLAIHHFEKAVTlDPNFLDAYINlgNVLKEARIFDRAVAAYLRALSl 254
Cdd:COG3071  137 ELLE-LLPALRKHKALSAEEA-------QALERRAYLGLLRQAAR-DAEALKALWK--ALPRAERRDPELAAAYARALI- 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  255 spnhavvhgnlacvyyEQGLIDLAIDTYRRAIELQPH--FPDAY--CNLANALKekgSVAEAEDcyntALRLCPTHADSL 330
Cdd:COG3071  205 ----------------ALGDHDEAERLLREALKRQWDprLVRLYgrLQGGDPAK---QLKRAEK----WLKKHPNDPDLL 261

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 46909607  331 NNLANIKREQGNIEEAVRLYRKALEVFPEfAAAHSNLASVLQQQGKLQEALMHYKEAIR 389
Cdd:COG3071  262 LALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALA 319
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 361-394 5.75e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 5.75e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     361 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 394
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 395-428 5.98e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 5.98e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     395 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 428
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 293-326 5.98e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 5.98e-05
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 326
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 264-327 8.07e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.55  E-value: 8.07e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607    264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPD---AYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 327
Cdd:pfam13432    2 ALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
TPR_1 pfam00515
Tetratricopeptide repeat;
429-462 8.84e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.48  E-value: 8.84e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    429 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 462
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 24-190 9.86e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.96  E-value: 9.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    24 LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRsahfstlAIKqnplLAEAYSNLGnvykeRG 103
Cdd:PRK11788  110 LQELGQDYLKAGLLDRAEELFLQLVDEGDFAEGALQQLLEIYQQEKDWQK-------AID----VAERLEKLG-----GD 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   104 QLQEAIEHYrhalrlkpdfidgYINLAAALVAAGDMEGAVQAYVSALQYNPDlyCVRS--DLGNLLKALGRLEEAKACYL 181
Cdd:PRK11788  174 SLRVEIAHF-------------YCELAQQALARGDLDAARALLKKALAADPQ--CVRAsiLLGDLALAQGDYAAAIEALE 238


                  ....*....
gi 46909607   182 KAIETQPNF 190
Cdd:PRK11788  239 RVEEQDPEY 247
TPR_19 pfam14559
Tetratricopeptide repeat;
103-155 1.05e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 41.03  E-value: 1.05e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 46909607    103 GQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD 155
Cdd:pfam14559    2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPD 54
TPR_7 pfam13176
Tetratricopeptide repeat;
91-121 1.05e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 40.22  E-value: 1.05e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 46909607     91 AYSNLGNVYKERGQLQEAIEHYRHALRLKPD 121
Cdd:pfam13176    1 ALLNLGRIYRKLGDYDEAISLYEQALALAKD 31
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 298-358 1.33e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 1.33e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    298 NLANALKEKGSVAEAEDCYNTALRL---CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP 358
Cdd:pfam13432    2 ALARAALRAGDYDDAAAALEAALARfpeSPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
COG3899 COG3899
Predicted ATPase [General function prediction only];
24-178 1.46e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 46.00  E-value: 1.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERHC---------MQLWRQEPDNTGVLL--LLSSIHFQCRRLDRSAHFSTLAIK------QNP 86
Cdd:COG3899  748 LLELAEALYLAGRFEEAEALLeralaaralAALAALRHGNPPASAraYANLGLLLLGDYEEAYEFGELALAlaerlgDRR 827

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   87 LLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNL 166
Cdd:COG3899  828 LEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAA 907

                        170
                 ....*....|..
gi 46909607  167 LKALGRLEEAKA 178
Cdd:COG3899  908 AAAAALAAAELA 919
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-150 1.48e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     24 LAELAHREyqaGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQcRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERG 103
Cdd:TIGR02917  776 LAELYLAQ---KDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLE-LKDPRALEYAERALKLAPNIPAILDTLGWLLVEKG 851

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 46909607    104 QLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSAL 150
Cdd:TIGR02917  852 EADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKLL 898
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 429-462 1.63e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.74  E-value: 1.63e-04
                            10        20        30
                    ....*....|....*....|....*....|....
gi 46909607     429 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 462
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 241-364 1.87e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.19  E-value: 1.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   241 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP-HFPDAYCNLANALKEKGSVAEAEDCYNTA 319
Cdd:PRK11788  196 LDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPeYLSEVLPKLMECYQALGDEAEGLEFLRRA 275

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 46909607   320 LRLCPThADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
Cdd:PRK11788  276 LEEYPG-ADLLLALAQLLEEQEGPEAAQALLREQLRRHPSLRGFH 319
TPR_17 pfam13431
Tetratricopeptide repeat;
315-348 2.30e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.45  E-value: 2.30e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    315 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVR 348
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 276-430 2.33e-04

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 44.11  E-value: 2.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  276 DLAIDTYRRAIELQ-----PHfpDA---YCNLANALKeKGSVAEAEDCYNTALRL------CPTHADSLNNLANI-KREQ 340
Cdd:cd15832   49 EEAGDAFLKAAECQlkldsKH--DAanaYVEAAKCYK-KVDPQEAVNCLEKAIEIytemgrFRQAAKHLKEIAELyENEL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  341 GNIEEAVRLYRKALEVFP-EFAAAHSN-----LASVLQQQGKLQEALMHYKEAIRISptfadaysnMGNTL-----KE-- 407
Cdd:cd15832  126 GDLDKAIEAYEQAADYYEgEGANSLANkcylkVADLAAQLEDYDKAIEIYEQVARSS---------LENNLlkysaKDyf 196

                        170       180       190
                 ....*....|....*....|....*....|..
gi 46909607  408 ---------MQDVQGALQCYTRAIQINPAFAD 430
Cdd:cd15832  197 lkaglchlaAGDVVAAQRALEKYAELDPSFAG 228
TPR_10 pfam13374
Tetratricopeptide repeat;
88-118 2.36e-04

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 39.41  E-value: 2.36e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 46909607     88 LAEAYSNLGNVYKERGQLQEAIEHYRHALRL 118
Cdd:pfam13374    1 TASSLNNLANALRAQGRYDEAEELLEEALAI 31
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 16-178 2.46e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     16 KRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSA-HFSTLaIKQNPLLAEAYSN 94
Cdd:TIGR02917  731 KRAPSSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIkHYQTV-VKKAPDNAVVLNN 809

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     95 LGNVYKERGQlQEAIEHYRHALRLKP---DFIDGYinlAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALG 171
Cdd:TIGR02917  810 LAWLYLELKD-PRALEYAERALKLAPnipAILDTL---GWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATG 885


                   ....*..
gi 46909607    172 RLEEAKA 178
Cdd:TIGR02917  886 RKAEARK 892
COG3899 COG3899
Predicted ATPase [General function prediction only];
24-397 2.50e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.23  E-value: 2.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   24 LAELAHREYQAGDFEAAERH---CMQLWRQEPDNTG---VLLLLSSIHFQCRRLDRSAHFSTLAIKQN------------ 85
Cdd:COG3899  708 LLRAARRALARGAYAEALRYlerALELLPPDPEEEYrlaLLLELAEALYLAGRFEEAEALLERALAARalaalaalrhgn 787

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   86 -PLLAEAYSNLGNVYkeRGQLQEAIEHYRHALRLKPDFID------GYINLAAALVAAGDMEGAVQAYVSALQYnpDLYC 158
Cdd:COG3899  788 pPASARAYANLGLLL--LGDYEEAYEFGELALALAERLGDrrlearALFNLGFILHWLGPLREALELLREALEA--GLET 863

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  159 VRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSnLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYinlgnvlkEA 238
Cdd:COG3899  864 GDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAA-AAALAAAAAAAALAAAELARLAAAAAAAAALA--------LA 934

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  239 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR---AIELQPHFPDAYCNLANALKEKGSVAEAEDC 315
Cdd:COG3899  935 AAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAaaaAAAAAAALEAAAAALLALLAAAAAAAAAAAA 1014

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  316 YNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 395
Cdd:COG3899 1015 LAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAA 1094


                 ..
gi 46909607  396 DA 397
Cdd:COG3899 1095 AA 1096
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
180-355 2.67e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 43.72  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  180 YLKAIETQPNFAVAWSNLGCVFNAQGEIWLAihhfEKAVTLDPNFlDAYINLGNVLKEARIFDRAVAAYLRALS-LSPNH 258
Cdd:COG4700   49 VLPELRNSRDARRVQRAARNALDPGRELREL----EKALEFADTV-QNRVRLADALLELGRYDEAIELYEEALTgIFADD 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  259 AVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHF--PDAYCNLANALKEKGSVAEAEDCYNTALRLCPtHADSLNNLANI 336
Cdd:COG4700  124 PHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLLYARALEALGDLEAAEAELEALARRYS-GPEARYRYAKF 202

                        170
                 ....*....|....*....
gi 46909607  337 KREQGNIEEAVRLYRKALE 355
Cdd:COG4700  203 LARQGRTAEAKELLEEILD 221
SNAP pfam14938
Soluble NSF attachment protein, SNAP; The soluble NSF attachment protein (SNAP) proteins are ...
 294-452 2.91e-04

Soluble NSF attachment protein, SNAP; The soluble NSF attachment protein (SNAP) proteins are involved in vesicular transport between the endoplasmic reticulum and Golgi apparatus. They act as adaptors between SNARE (integral membrane SNAP receptor) proteins and NSF (N-ethylmaleimide-sensitive factor). They are structurally similar to TPR repeats.


Pssm-ID: 405606 [Multi-domain]  Cd Length: 273  Bit Score: 44.10  E-value: 2.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    294 DAYCNLANALKEKGSVAEAEDCYNTALRlCPTHADSLNNLAN--------IKReqGNIEEAVRLYRKALEVFpefaaahs 365
Cdd:pfam14938   28 DLYIQAANAYKLAKNWEEAGEAFEKAAE-CQLKLGSKDEAANayveaakcYKK--VDPEEAVRALEKAIEIY-------- 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    366 nlasvlQQQGKLQEALMHYKEAirisptfADAYSNmgntlkEMQDVQGALQCYTRA---IQINPAFADAHSNL---ASIH 439
Cdd:pfam14938   97 ------TEMGRFRRAAKHKKEI-------AELYEQ------ELGDLEKAIEAYEQAadwYEGEGASALANKCYlkvADLS 157

                          170
                   ....*....|...
gi 46909607    440 KDSGNIPEAIASY 452
Cdd:pfam14938  158 AELEDYPKAIEIY 170
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 750-830 3.03e-04

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 40.73  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   750 DVKIVKMKCPDGGDNPDSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 828
Cdd:NF038028    1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                  ..
gi 46909607   829 VT 830
Cdd:NF038028   70 FT 71
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 327-359 3.36e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.66  E-value: 3.36e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 264-391 3.55e-04

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 43.88  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  264 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA-----NALKEKGSVaeaedcynTALRLCPTHADSLNNLANIKR 338
Cdd:cd24145  152 ELATAYDLYGRFCLALPLYMQALSLKGQILLSQANCHslvlmNNEAAELAL--------HALRKPLSSTLIEASRLPQKS 223

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46909607  339 EQGNIEEAVRLYRKALEVF---------PE----FAAAHSNLASVLQQQGKLQEALMHYKEAIRIS 391
Cdd:cd24145  224 RDQLLEAALKWAQKALDVAksikpkdrdPEcdqaCALALYNLGVIAEMLGNLDEARKLYKEAISLA 289
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
 210-290 3.70e-04

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 468245 [Multi-domain]  Cd Length: 255  Bit Score: 43.31  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 289
Cdd:NF033920  175 ALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALA 254


                  .
gi 46909607   290 P 290
Cdd:NF033920  255 P 255
TPR_19 pfam14559
Tetratricopeptide repeat;
374-438 4.07e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.49  E-value: 4.07e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    374 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 438
Cdd:pfam14559    1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_19 pfam14559
Tetratricopeptide repeat;
340-380 4.11e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.49  E-value: 4.11e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 46909607    340 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 380
Cdd:pfam14559    1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEA 41
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 230-290 4.24e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.63  E-value: 4.24e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607    230 NLGNVLKEARIFDRAVAAYLRAL---SLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 290
Cdd:pfam13432    2 ALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAP 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 22-185 4.27e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.77  E-value: 4.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   22 QGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLL-AEAYSNLgnvyk 100
Cdd:cd24142    1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYL----- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  101 erGQL---QEAIEHYR----------HALRLKPDFIDGYIN-----LAAALVAAG-----------DMEGAVQAYV-SAL 150
Cdd:cd24142   76 --GQLsggEEALQYYEkgieileeelQALQAASAEAEEEAEelkrkLSSALCALAeiymtdlcdepDAEQRCEELItKAL 153

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 46909607  151 QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIE 185
Cdd:cd24142  154 ELDPTNPEALQTLASLRISQQRPDEAKEALRRSLE 188
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 81-288 4.36e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.20  E-value: 4.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAaalvaagdmegavqayvsALQYNpdlycvr 160
Cdd:TIGR00990  391 ALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLG------------------VTQYK------- 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    161 sdlgnllkaLGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI 240
Cdd:TIGR00990  446 ---------EGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLINKALA 516

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    241 FDRAVAAYL-------RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIEL 288
Cdd:TIGR00990  517 LFQWKQDFIeaenlceKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAEL 571
TPR_1 pfam00515
Tetratricopeptide repeat;
163-190 4.93e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.93e-04
                           10        20
                   ....*....|....*....|....*...
gi 46909607    163 LGNLLKALGRLEEAKACYLKAIETQPNF 190
Cdd:pfam00515    7 LGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 340-448 5.91e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 43.45  E-value: 5.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    340 QGNIEEAVRLYRKALEvfpeFAAAHSN----------LASVLQQQGKLQEALMHYKEAIR--------ISPTFADAYSNM 401
Cdd:pfam17874   53 LGDLDAALQAMREAEA----LARRADSphvtlwallqQGEILRAQGRLHQALETYQQALQlardhglqHLPLHGFLLVGL 128

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 46909607    402 GNTLKEMQDVQGALQCYTRAIQI-----NPAFADAHSNLASIHKDSGNIPEA 448
Cdd:pfam17874  129 ADLLYEWNDLEEAEQHAQQGIQLgrqwePDAAVDAYVLLARIALAQGELEEA 180
TPR_17 pfam13431
Tetratricopeptide repeat;
81-110 6.27e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 38.29  E-value: 6.27e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 46909607     81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIE 110
Cdd:pfam13431    5 ALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_17 pfam13431
Tetratricopeptide repeat;
281-313 7.41e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 37.91  E-value: 7.41e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    281 TYRRAIELQPHFPDAYCNLANALKEKGSVAEAE 313
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETAL 33
ST7 cd11557
Suppression of tumorigenicity 7; ST7 is a metazoan protein that behaves as a tumor suppressor ...
 279-426 7.47e-04

Suppression of tumorigenicity 7; ST7 is a metazoan protein that behaves as a tumor suppressor in human cancer cells. It appears to localize to the cytoplasm and plasma membrane, and may mediate tumor suppression by regulating genes that are involved in oncogenic pathways and/or maintain cellular structure. It has been suggested that the suppression of tumorigenicity is associated with a function in mediating the remodeling of the extracellular matrix. However, somatic mutations of ST7 have not been observed as being commonly associated with molecular pathogenesis in various human neoplasias.


Pssm-ID: 211407 [Multi-domain]  Cd Length: 458  Bit Score: 43.14  E-value: 7.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  279 IDTYRRAIELQPHFPDAYCNLANalKEKGSVAEAEDCYNTALRLC------------------PTHADSLNNLANIK--- 337
Cdd:cd11557  142 IKAAHEALELNPECATALILLAE--EEAQTILEAEKLLKQALKAAeanyrksqqlqhqdpqheAVHRRDTNVLVYIKrrl 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  338 ----REQGNIEEAVRLYRKALEVFPEFAAA--HSNLASVL---QQQGKLQEALMHYKEA-----IRISPTFA-------- 395
Cdd:cd11557  220 amcaRKLGRLKEAVKMMRDLMKEFPLLSVLniHENLIEALlelQAYADVQAVLAKYDDIslpksATICYTAAllkarava 299

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 46909607  396 -----DAYSNMGNTLKEMQdvqgALQCYTRAIQINP 426
Cdd:cd11557  300 dkfspEVASRRGLSTAEMN----AVEAIHRAVEFNP 331
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
438-473 7.88e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 7.88e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 46909607  438 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 473
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLL 36
TPR_11 pfam13414
TPR repeat;
232-273 8.24e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 8.24e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607    232 GNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG 273
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 293-325 8.54e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.89  E-value: 8.54e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    293 PDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_11 pfam13414
TPR repeat;
300-341 9.55e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 9.55e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 46909607    300 ANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_8 pfam13181
Tetratricopeptide repeat;
163-189 9.89e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 37.38  E-value: 9.89e-04
                           10        20
                   ....*....|....*....|....*..
gi 46909607    163 LGNLLKALGRLEEAKACYLKAIETQPN 189
Cdd:pfam13181    7 LGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 429-461 1.01e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.50  E-value: 1.01e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    429 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 461
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR-S pfam20308
Tetratricopeptide Repeats-Sensor; This entry represents a sensor domain consisting of 7 TPR ...
 36-133 1.08e-03

Tetratricopeptide Repeats-Sensor; This entry represents a sensor domain consisting of 7 TPR repeats forming a tightly-wound solenoid structure harbouring a deep central pocket. The TPR-S binding pocket is lined with several conserved aromatic and polar residues predicted to bind a NAD+-derived nucleotide in prokaryotic NAD+-derived nucleotide-activated effector conflict systems. It has been acquired at the base of the choanoflagellate-animal lineage as a core component of the ASK signalosome.


Pssm-ID: 466458 [Multi-domain]  Cd Length: 105  Bit Score: 39.56  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     36 DFEAAeRHCMQLWRQEPDNTGVLLLLSsihF----QCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKER--------G 103
Cdd:pfam20308    1 DYDAA-VELLEALLALPEDARAQEQLA---LalarLPGDRDEALDVLEDLIERLGEDPETLGLLGRIYKRLwlesaedrE 76

                           90       100       110
                   ....*....|....*....|....*....|
gi 46909607    104 QLQEAIEHYRHALRLKPDFIDGyINLAAAL 133
Cdd:pfam20308   77 ALDQAIEAYRKAFELDPDDYPG-INAATLL 105
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 341-458 1.09e-03

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 40.36  E-value: 1.09e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607     341 GNIEEAVRLYRKAL-----EVFPEFAAAhsnlASVLQQQGKLQEALMHYKEAIrisptfADAYSNMGntlkemqDVQGAL 415
Cdd:smart01043   19 ADPEAALALLEAALalyrgPLLADVPDE----DWAEAERERLRELRLEALEAL------AEALLALG-------RHEEAL 81

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|...
gi 46909607     416 QCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Cdd:smart01043   82 ALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLRRL 124
TPR_17 pfam13431
Tetratricopeptide repeat;
349-381 1.10e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 37.52  E-value: 1.10e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    349 LYRKALEVFPEFAAAHSNLASVLQQQGKLQEAL 381
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETAL 33
TPR COG0790
TPR repeat [General function prediction only];
226-389 1.23e-03

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 41.84  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  226 DAYINLGNVLKEARI----FDRAVAAYLRALSLspNHAVVHGNLAcVYYEQGL-----IDLAIDTYRRAIELQphFPDAY 296
Cdd:COG0790   64 EAQYNLGLMYAEGRGvpkdYEKALEWFEKAAEQ--GDAEAQYNLG-LMYEEGLgvpqdYAKALEWYEKAAEQG--DADAQ 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  297 CNLANALKE----KGSVAEAEDCYNTALRLcpTHADSLNNLANIKRE----QGNIEEAVRLYRKALEVfpEFAAAHSNLA 368
Cdd:COG0790  139 YNLGLLYLNgegvPKDPAKAAEWYRKAAEQ--GDADAQYNLGVLYENgrgvPKDPAKALEWYRKAAEQ--GDADAQYNLG 214

                        170       180
                 ....*....|....*....|....*.
gi 46909607  369 sVLQQQGK-----LQEALMHYKEAIR 389
Cdd:COG0790  215 -RLYLNGEgvekdLEKALRWLRKAAE 239
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 91-220 1.25e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 41.95  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   91 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAgdmegAVQAYVSALQYNPDLYCVRSDLGNLLKA- 169
Cdd:cd24145  149 FLEELATAYDLYGRFCLALPLYMQALSLKGQILLSQANCHSLVLMN-----NEAAELALHALRKPLSSTLIEASRLPQKs 223

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607  170 -LGRLEEAKACYLKAI-------------ETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL 220
Cdd:cd24145  224 rDQLLEAALKWAQKALdvaksikpkdrdpECDQACALALYNLGVIAEMLGNLDEARKLYKEAISL 288
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 395-426 1.30e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 1.30e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 46909607    395 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 426
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
226-258 1.33e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 1.33e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    226 DAYINLGNVLKEARIFDRAVAAYLRALSLSPNH 258
Cdd:pfam00515    2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_7 pfam13176
Tetratricopeptide repeat;
329-356 1.50e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 37.13  E-value: 1.50e-03
                           10        20
                   ....*....|....*....|....*...
gi 46909607    329 SLNNLANIKREQGNIEEAVRLYRKALEV 356
Cdd:pfam13176    1 ALLNLGRIYRKLGDYDEAISLYEQALAL 28
TPR_17 pfam13431
Tetratricopeptide repeat;
383-416 1.85e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.75  E-value: 1.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 46909607    383 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQ 416
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_19 pfam14559
Tetratricopeptide repeat;
410-466 2.09e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.56  E-value: 2.09e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607    410 DVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 466
Cdd:pfam14559    3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYA 59
StaR_like cd05804
StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member ...
 120-280 2.14e-03

StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been speculated that StaR could be a flavoprotein hydroxylating a tyrosine sidechain. Some family members have been annotated as proteins containing tetratricopeptide (TPR) repeats, which may at least indicate mostly alpha-helical secondary structure.


Pssm-ID: 100115 [Multi-domain]  Cd Length: 355  Bit Score: 41.50  E-value: 2.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  120 PDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDlycvRSD---------LGNLLKalGRLEEAKACYLKAIETQPNF 190
Cdd:cd05804    3 PDFALGHAAAALLLLLGGERPAAAAKAAAAAQALAA----RATererahveaLSAWIA--GDLPKALALLEQLLDDYPRD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  191 AVAWSNLGCVFNAQGEIWLAiHHFEKAVTL-DP-NFLDAYIN--LGNVLKEARIFDRAVAAYLRALSLSPN-----HAVV 261
Cdd:cd05804   77 LLALKLHLGAFGLGDFSGMR-DHVARVLPLwAPeNPDYWYLLgmLAFGLEEAGQYDRAEEAARRALELNPDdawavHAVA 155

                        170
                 ....*....|....*....
gi 46909607  262 HgnlacVYYEQGLIDLAID 280
Cdd:cd05804  156 H-----VLEMQGRFKEGIA 169
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 34-163 2.70e-03

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 41.82  E-value: 2.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    34 AGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLlAEAYSNLGNVYKERGQLQEAIEHYR 113
Cdd:PRK09782  555 AGNGAARDRWLQQAEQRGLGDNALYWWLHAQRYIPGQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLR 633

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 46909607   114 HALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL 163
Cdd:PRK09782  634 AALELEPNNSNYQAALGYALWDSGDIAQSREMLERAHKGLPDDPALIRQL 683
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 226-258 2.71e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 2.71e-03
                            10        20        30
                    ....*....|....*....|....*....|...
gi 46909607     226 DAYINLGNVLKEARIFDRAVAAYLRALSLSPNH 258
Cdd:smart00028    2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_14 pfam13428
Tetratricopeptide repeat;
333-370 2.80e-03

Tetratricopeptide repeat;


Pssm-ID: 463874 [Multi-domain]  Cd Length: 44  Bit Score: 36.63  E-value: 2.80e-03
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 46909607    333 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASV 370
Cdd:pfam13428    7 LARALLALGDPDEALALLERALALDPDDPEAWLALAQL 44
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 400-461 2.80e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.32  E-value: 2.80e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    400 NMGNTLKEMQDVQGALQCYTRAIQIN---PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 461
Cdd:pfam13432    2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 163-190 2.82e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 2.82e-03
                            10        20
                    ....*....|....*....|....*...
gi 46909607     163 LGNLLKALGRLEEAKACYLKAIETQPNF 190
Cdd:smart00028    7 LGNAYLKLGDYDEALEYYEKALELDPNN 34
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 203-307 3.14e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 39.66  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607   203 AQGEIWLAIHHFEKAVTLDPNFLD-AYI--NLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQG------ 273
Cdd:PRK02603   47 ADGEYAEALENYEEALKLEEDPNDrSYIlyNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGekaeea 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 46909607   274 --------LIDLAIDTYRRAIELqphFPDAYCNLANALKEKG 307
Cdd:PRK02603  127 gdqdeaeaLFDKAAEYWKQAIRL---APNNYIEAQNWLKTTG 165
TPR_17 pfam13431
Tetratricopeptide repeat;
179-211 3.65e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.98  E-value: 3.65e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    179 CYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAI 211
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETAL 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 132-223 3.96e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.05  E-value: 3.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  132 ALVAAGDMEGAVQAYVSALQYNPD-------LYcvrsDLGNLLKALGRLEEAKACYLKAIETQPN---FAVAWSNLGCVF 201
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNsplapdaLY----WLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSY 77

                         90       100
                 ....*....|....*....|..
gi 46909607  202 NAQGEIWLAIHHFEKAVTLDPN 223
Cdd:COG1729   78 LELGDYDKARATLEELIKKYPD 99
TPR_8 pfam13181
Tetratricopeptide repeat;
327-359 4.00e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.84  E-value: 4.00e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    327 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 359
Cdd:pfam13181    1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_11 pfam13414
TPR repeat;
198-237 4.53e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.91  E-value: 4.53e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 46909607    198 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKE 237
Cdd:pfam13414    1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
327-457 5.36e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.87  E-value: 5.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  327 ADSLNN---LANIKREQGNIEEAVRLYRKALE-VFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF--ADAYSN 400
Cdd:COG4700   86 ADTVQNrvrLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFksSDAHLL 165

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 46909607  401 MGNTLKEMQDVQGALQCYTRAIQINPaFADAHSNLASIHKDSGNIPEAIASYRTALK 457
Cdd:COG4700  166 YARALEALGDLEAAEAELEALARRYS-GPEARYRYAKFLARQGRTAEAKELLEEILD 221
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 361-393 5.70e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 5.70e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 46909607    361 AAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
Cdd:pfam07719    1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 342-455 6.23e-03

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 39.87  E-value: 6.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  342 NIEEAVRLYRKAlevfpefaAAHSNLASVLQQQGK--LQEALMHYK-----EAirisptfADAYSNMGNTLKEMqDVQGA 414
Cdd:cd15832   27 KYEEAAELYEKA--------ANAFKLAKNWEEAGDafLKAAECQLKldskhDA-------ANAYVEAAKCYKKV-DPQEA 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 46909607  415 LQCYTRAIQI-------NPAfADAHSNLASIH-KDSGNIPEAIASYRTA 455
Cdd:cd15832   91 VNCLEKAIEIytemgrfRQA-AKHLKEIAELYeNELGDLDKAIEAYEQA 138
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 340-423 6.57e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.99  E-value: 6.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607    340 QGNIEEAVRLYRKAL-----EVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRisptFADAYSNMGNT------LKEM 408
Cdd:pfam17874   14 KGDAERALELAEQALallpeDDLLARGLATFVLGEAYLCLGDLDAALQAMREAEA----LARRADSPHVTlwallqQGEI 89

                           90
                   ....*....|....*....
gi 46909607    409 QDVQG----ALQCYTRAIQ 423
Cdd:pfam17874   90 LRAQGrlhqALETYQQALQ 108
TPR_9 pfam13371
Tetratricopeptide repeat;
231-295 7.56e-03

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 36.04  E-value: 7.56e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46909607    231 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA 295
Cdd:pfam13371    1 LKAIYLREEDWERALAVVERLLLLAPDDPEERRDRGLLYAQLGCFQAALEDLEAYLELAPDAPDA 65
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 226-257 7.74e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 7.74e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 46909607    226 DAYINLGNVLKEARIFDRAVAAYLRALSLSPN 257
Cdd:pfam07719    2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 407-474 8.26e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 8.26e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46909607  407 EMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIPEAIASYRTALKLKPD---FPDAYCNLAHCLQ 474
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYL 78
TPR_7 pfam13176
Tetratricopeptide repeat;
431-466 9.25e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 34.82  E-value: 9.25e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 46909607    431 AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 466
Cdd:pfam13176    1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 333-427 9.78e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 38.68  E-value: 9.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46909607  333 LANIKREQGNIEEAVRLYRKALE--VFPEFAA-AHSNLASVLQQQGKLQEALMHYKEAirISPTFADAYSN-MGNTLKEM 408
Cdd:COG2976   96 LAKAAVDAGDLDKAAAQLQWVLDnaKDPALKAlARLRLARVLLAQKKYDEALATLDAV--KPEAFAALYAElRGDILLAQ 173

                         90
                 ....*....|....*....
gi 46909607  409 QDVQGALQCYTRAIQINPA 427
Cdd:COG2976  174 GDKAEARAAYQKALAALPE 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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