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Conserved domains on  [gi|18412918|ref|NP_565249|]
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Phospholipid/glycerol acyltransferase family protein [Arabidopsis thaliana]

Protein Classification

glycerol-3-phosphate acyltransferase( domain architecture ID 10168560)

glycerol-3-phosphate acyltransferase (GPAT) catalyzes the incorporation of an acyl group from acylCoA into the acceptor glycerol 3-phosphate

CATH:  1.10.1200.50
EC:  2.3.1.-
Gene Ontology:  GO:0008374
SCOP:  4003349

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 2.30e-84

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


:

Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 255.99  E-value: 2.30e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991   2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991  58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 300 LKYPYeRFSVAWDTISGA---RHILFLLCQVVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991 133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                .
gi 18412918 377 R 377
Cdd:cd07991 211 R 211
 
Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 2.30e-84

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 255.99  E-value: 2.30e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991   2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991  58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 300 LKYPYeRFSVAWDTISGA---RHILFLLCQVVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991 133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                .
gi 18412918 377 R 377
Cdd:cd07991 211 R 211
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 190-302 1.93e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 99.74  E-value: 1.93e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918    190 IVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvSGTVNERVREAHSNKSa 264
Cdd:smart00563   3 VVANHQSFLDPLVLSALLPrklgrVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKA----RAALREAVELLKEGEW- 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 18412918    265 ptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKY 302
Cdd:smart00563  78 --LLIFPEGTRSRPGKLLPFKKGAARlaleAGVPIVPVAIRG 117
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 184-363 7.60e-25

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 100.85  E-value: 7.60e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 184 PERPGAIVSNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKgvsgTVNERVREAHS 260
Cdd:COG0204  41 ADGPVLIVANHQSWLDILL-LLAALPrpvRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALR----ALRQAVEALKA 115

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 261 NKSaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERFSvaWDTISGARHIlfllcqvvnhlEVIRL 336
Cdd:COG0204 116 GES---LVIFPEGTRSPDGRLLPFKTGAARlaleAGVPIVPVAIDGTERALP--KGFLPRPGKV-----------TVRIG 179

                       170       180
                ....*....|....*....|....*..
gi 18412918 337 PVYYPSQEEKDDPKLYASNVRKLMATE 363
Cdd:COG0204 180 PPIDPSDLEGEDRRELAERLRAAIEAL 206
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 184-301 3.48e-21

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 88.49  E-value: 3.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918   184 PERPGAIVSNHVSYLD------ILYHMSASfPSFVAKRSVGKLPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVRE 257
Cdd:pfam01553  12 RGGPAIVVANHQSYLDvlllslALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDRK----NRKDAAGTLEYLVEL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 18412918   258 AHSNKSaptIMLFPEGTTTNGDYLLTFKTGAF----LAGTPVLPVILK 301
Cdd:pfam01553  87 LREGKL---VVIFPEGTRSREGELLPFKKGAFrlaiEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 184-300 1.72e-20

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 86.63  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918   184 PERPGAIV-SNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvsGTVNERVREAH 259
Cdd:TIGR00530  13 PAKSPVLVvANHQSNLDPLT-LSAAFPppiVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAI-----ATALKAAIEVL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 18412918   260 SNKSAptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:TIGR00530  87 KQGRS--IGVFPEGTRSRGRDILPFKKGAFHiaikAGVPILPVVL 129
PLN02833 PLN02833
glycerol acyltransferase family protein
 186-366 3.08e-11

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 64.41  E-value: 3.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  186 RPGAI-VSNHVSYLD--ILYHMSAsFpSFVAKRSVGklpLVGLISK----CLGCVYVQR-EAKSPDfkgvsgTVNERVRE 257
Cdd:PLN02833 162 RPKQVfVANHTSMIDfiVLEQMTP-F-AVIMQKHPG---WVGFLQNtileSVGCIWFNRtEAKDRE------VVAKKLRD 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  258 AHSNKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVILKYPYERFSVAWDT--ISGARHilflLCQVVNHLEVIr 335
Cdd:PLN02833 231 HVQDPDRNPLLIFPEGTCVNNEYTVMFKKGAFELGCTVCPIAIKYNKIFVDAFWNSrkQSFTMH----LLRLMTSWAVV- 305

                        170       180       190
                 ....*....|....*....|....*....|....
gi 18412918  336 LPVYYPSQEEK---DDPKLYASNVRKLMATEGNL 366
Cdd:PLN02833 306 CDVWYLEPQTLrpgETPIEFAERVRDMIAKRAGL 339
 
Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 2.30e-84

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 255.99  E-value: 2.30e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991   2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991  58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 300 LKYPYeRFSVAWDTISGA---RHILFLLCQVVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991 133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                .
gi 18412918 377 R 377
Cdd:cd07991 211 R 211
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 190-302 1.93e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 99.74  E-value: 1.93e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918    190 IVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvSGTVNERVREAHSNKSa 264
Cdd:smart00563   3 VVANHQSFLDPLVLSALLPrklgrVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKA----RAALREAVELLKEGEW- 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 18412918    265 ptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKY 302
Cdd:smart00563  78 --LLIFPEGTRSRPGKLLPFKKGAARlaleAGVPIVPVAIRG 117
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 184-307 2.75e-25

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 101.19  E-value: 2.75e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 184 PERPGAIVSNHVSYLDILYHMSASFP--SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVSgTVNERVREAHSn 261
Cdd:cd07989  22 PKGPVIIVANHQSYLDPLVLGAALPRpiRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALR-EAIEALKEGES- 99

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 18412918 262 ksaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERF 307
Cdd:cd07989 100 -----VVIFPEGTRSRDGELLPFKSGAFRlakeAGVPIVPVAISGTWGSL 144
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 184-363 7.60e-25

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 100.85  E-value: 7.60e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 184 PERPGAIVSNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKgvsgTVNERVREAHS 260
Cdd:COG0204  41 ADGPVLIVANHQSWLDILL-LLAALPrpvRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALR----ALRQAVEALKA 115

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 261 NKSaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERFSvaWDTISGARHIlfllcqvvnhlEVIRL 336
Cdd:COG0204 116 GES---LVIFPEGTRSPDGRLLPFKTGAARlaleAGVPIVPVAIDGTERALP--KGFLPRPGKV-----------TVRIG 179

                       170       180
                ....*....|....*....|....*..
gi 18412918 337 PVYYPSQEEKDDPKLYASNVRKLMATE 363
Cdd:COG0204 180 PPIDPSDLEGEDRRELAERLRAAIEAL 206
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 184-301 3.48e-21

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 88.49  E-value: 3.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918   184 PERPGAIVSNHVSYLD------ILYHMSASfPSFVAKRSVGKLPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVRE 257
Cdd:pfam01553  12 RGGPAIVVANHQSYLDvlllslALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDRK----NRKDAAGTLEYLVEL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 18412918   258 AHSNKSaptIMLFPEGTTTNGDYLLTFKTGAF----LAGTPVLPVILK 301
Cdd:pfam01553  87 LREGKL---VVIFPEGTRSREGELLPFKKGAFrlaiEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 184-300 1.72e-20

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 86.63  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918   184 PERPGAIV-SNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvsGTVNERVREAH 259
Cdd:TIGR00530  13 PAKSPVLVvANHQSNLDPLT-LSAAFPppiVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAI-----ATALKAAIEVL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 18412918   260 SNKSAptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:TIGR00530  87 KQGRS--IGVFPEGTRSRGRDILPFKKGAFHiaikAGVPILPVVL 129
PLN02833 PLN02833
glycerol acyltransferase family protein
 186-366 3.08e-11

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 64.41  E-value: 3.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  186 RPGAI-VSNHVSYLD--ILYHMSAsFpSFVAKRSVGklpLVGLISK----CLGCVYVQR-EAKSPDfkgvsgTVNERVRE 257
Cdd:PLN02833 162 RPKQVfVANHTSMIDfiVLEQMTP-F-AVIMQKHPG---WVGFLQNtileSVGCIWFNRtEAKDRE------VVAKKLRD 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  258 AHSNKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVILKYPYERFSVAWDT--ISGARHilflLCQVVNHLEVIr 335
Cdd:PLN02833 231 HVQDPDRNPLLIFPEGTCVNNEYTVMFKKGAFELGCTVCPIAIKYNKIFVDAFWNSrkQSFTMH----LLRLMTSWAVV- 305

                        170       180       190
                 ....*....|....*....|....*....|....
gi 18412918  336 LPVYYPSQEEK---DDPKLYASNVRKLMATEGNL 366
Cdd:PLN02833 306 CDVWYLEPQTLrpgETPIEFAERVRDMIAKRAGL 339
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 184-300 8.63e-09

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 55.12  E-value: 8.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  184 PERPGAIVSNHVSYLDI--LYHMSASFpSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVsgtvnERVREAHSN 261
Cdd:PLN02901  48 PDEPAVYVSNHQSFLDIytLFHLGRPF-KFISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECL-----KRCMELLKK 121

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 18412918  262 KSapTIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:PLN02901 122 GA--SVFFFPEGTRSKDGKLAAFKKGAFSvaakTGVPVVPITL 162
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 184-361 3.11e-08

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 53.19  E-value: 3.11e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 184 PERPGAIVSNHVSYLD------ILYHMSASFPSFVAKRSvgKLPLVGLISKClGCVYVQReaksPDFKGVSGTVNErVRE 257
Cdd:cd06551  24 GGGPVLFVSNHSSWWDglilflLLERGLRRDVYGLMDEE--LLERYPFFTRL-GAFSVDR----DSPRSAAKSLKY-VAR 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 258 AHSNKSAPtIMLFPEGTTTNGDY-LLTFKTGAF----LAGTPVLPVILKYPYERFsVAWDTIsgarhilfllcqvvnHLE 332
Cdd:cd06551  96 LLSKPGSV-VWIFPEGTRTRRDKrPLQFKPGVAhlaeKAGVPIVPVALRYTFELF-EQFPEI---------------FVR 158

                       170       180
                ....*....|....*....|....*....
gi 18412918 333 VIRLPVYYPSQEEKDDPKLYASNVRKLMA 361
Cdd:cd06551 159 IGPPIPYAETALGEELAAELANRLTRLLD 187
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 190-288 9.57e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 49.18  E-value: 9.57e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 190 IVSNHV-SYLDIL-YHMSASFP-SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfKGVSGTVNERVREAHSN--KSA 264
Cdd:cd07992  32 FLGNHPnALIDPLlLAATLRRPvRFLAKADLFKNPLIGWLLESFGAIPVYRPKDLAR-GGIGKISNAAVFDAVGEalKAG 110

                        90       100
                ....*....|....*....|....
gi 18412918 265 PTIMLFPEGTTTNGDYLLTFKTGA 288
Cdd:cd07992 111 GAIGIFPEGGSHDRPRLLPLKAGA 134
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 191-298 2.96e-06

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 48.09  E-value: 2.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918  191 VSNHVSYLDILYHMSASFPSFV--AKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVSGTVNervreaHSNKSAPTIM 268
Cdd:PRK15018  70 IANHQNNYDMVTASNIVQPPTVtvGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVN------HFKKRRISIW 143

                         90       100       110
                 ....*....|....*....|....*....|....
gi 18412918  269 LFPEGTTTNGDYLLTFKTGAF----LAGTPVLPV 298
Cdd:PRK15018 144 MFPEGTRSRGRGLLPFKTGAFhaaiAAGVPIIPV 177
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 190-274 4.53e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 43.77  E-value: 4.53e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 190 IVSNHVSYLDILYHMSASFPS-------FVAKRSVGKLPLVGLISKCLGCVYVQReakspdfkgvSGTVNERVREAHSNK 262
Cdd:cd07990  28 IISNHRSEVDWLVLWMLADRFgrlgrlkIVLKDSLKYPPLGGWGWQLGEFIFLKR----------KWEKDEKTIKRQLKR 97

                        90
                ....*....|....*..
gi 18412918 263 SAPT-----IMLFPEGT 274
Cdd:cd07990  98 LKDSpepfwLLIFPEGT 114
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 189-303 4.65e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 43.36  E-value: 4.65e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18412918 189 AIVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLvGLISKCLGCVYVQREAKSpdfkgvsGTVNERVREAHSNKS 263
Cdd:cd07988  24 VIGAPHTSNWDFVLGLLAAFalglkISFLGKHSLFKPPL-GPFMRWLGGIPVDRSRAG-------GLVEQVVEEFRRREE 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 18412918 264 ApTIMLFPEGTTTNGDYlltFKTG----AFLAGTPVLPVILKYP 303
Cdd:cd07988  96 F-VLAIAPEGTRSKVDK---WKTGfyhiARGAGVPILLVYLDYK 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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