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Conserved domains on  [gi|15830215|ref|NP_308988|]
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aquaporin [Escherichia coli O157:H7 str. Sakai]

Protein Classification

aquaporin Z( domain architecture ID 10012387)

aquaporin Z is involved in osmoregulation, allowing water to move into and out of the cell in response to osmotic pressure

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015250|GO:0006833
PubMed:  11964478|11473620|8849412
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-230 8.10e-136

aquaporin Z; Provisional


:

Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 380.47  E-value: 8.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    1 MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   81 VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG 160
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKR 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKD 230
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-230 8.10e-136

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 380.47  E-value: 8.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    1 MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   81 VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG 160
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKR 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKD 230
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 1-209 9.69e-69

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 210.75  E-value: 9.69e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   1 MFRKLAAECFGTFWLVFGGCGSAVLAAGFPElGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:COG0580   2 LMKRLLAEFLGTFILVLLGCGVVAVLAGTKG-GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  81 VVGYVIAQVVGGIVAAALLYLIASGKtgFDAAASGFASNGYGEHSPG-GYSMLSALVVELVLSAGFLLVIHGATD-KFAP 158
Cdd:COG0580  81 VLPYIIAQLLGAFLGAALVYLIYGGH--FDATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDkRAAP 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15830215 159 AGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQ----GGWALEQLWFFW 209
Cdd:COG0580 159 GGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPI 213
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 3-209 1.77e-61

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 192.08  E-value: 1.77e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   3 RKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  83 GYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKF---APA 159
Cdd:cd00333  81 PYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDPngpPPG 160

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 15830215 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGW-ALEQLWFFW 209
Cdd:cd00333 161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYW 211
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 7-209 3.17e-59

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 185.97  E-value: 3.17e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215     7 AECFGTFWLVFGGCGSAV---LAAGFPELGIG-FAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    83 GYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNgygehspgGYSMLSALVVELVLSAGFLLVIHGATDK---FAPA 159
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASA--------GVSSGQAFFVEFIGTAILVLVIFATTDDrnrVPRG 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 15830215   160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFW 209
Cdd:TIGR00861 153 GFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYW 202
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 3-209 4.97e-41

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 139.76  E-value: 4.97e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215     3 RKLAAECFGTFWLVFGGCGSAVLAAGFPELG--IGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALGVKKLVSSLavSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    81 VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASngygehspgGYSMLSALVVELVLSAGFLLVIHGATD---KFA 157
Cdd:pfam00230  89 AIFYIVAQLLGAIAGAALLYGVTVGLQRAGLFANTLAP---------GVNAGQAFVVEIILTFQLVYCVFATTDdrrNGS 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15830215   158 PAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalEQLWFFW 209
Cdd:pfam00230 160 LGTVAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWKW--DDHWVYW 209
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-230 8.10e-136

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 380.47  E-value: 8.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    1 MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:PRK05420   1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   81 VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG 160
Cdd:PRK05420  81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKR 230
Cdd:PRK05420 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKD 230
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 1-209 9.69e-69

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 210.75  E-value: 9.69e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   1 MFRKLAAECFGTFWLVFGGCGSAVLAAGFPElGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:COG0580   2 LMKRLLAEFLGTFILVLLGCGVVAVLAGTKG-GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWKD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  81 VVGYVIAQVVGGIVAAALLYLIASGKtgFDAAASGFASNGYGEHSPG-GYSMLSALVVELVLSAGFLLVIHGATD-KFAP 158
Cdd:COG0580  81 VLPYIIAQLLGAFLGAALVYLIYGGH--FDATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDkRAAP 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15830215 159 AGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQ----GGWALEQLWFFW 209
Cdd:COG0580 159 GGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPI 213
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 3-209 1.77e-61

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 192.08  E-value: 1.77e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   3 RKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215  83 GYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKF---APA 159
Cdd:cd00333  81 PYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDPngpPPG 160

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 15830215 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGW-ALEQLWFFW 209
Cdd:cd00333 161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYW 211
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 7-209 3.17e-59

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 185.97  E-value: 3.17e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215     7 AECFGTFWLVFGGCGSAV---LAAGFPELGIG-FAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    83 GYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNgygehspgGYSMLSALVVELVLSAGFLLVIHGATDK---FAPA 159
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASA--------GVSSGQAFFVEFIGTAILVLVIFATTDDrnrVPRG 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 15830215   160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFW 209
Cdd:TIGR00861 153 GFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYW 202
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 3-209 4.97e-41

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 139.76  E-value: 4.97e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215     3 RKLAAECFGTFWLVFGGCGSAVLAAGFPELG--IGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALGVKKLVSSLavSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    81 VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASngygehspgGYSMLSALVVELVLSAGFLLVIHGATD---KFA 157
Cdd:pfam00230  89 AIFYIVAQLLGAIAGAALLYGVTVGLQRAGLFANTLAP---------GVNAGQAFVVEIILTFQLVYCVFATTDdrrNGS 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15830215   158 PAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalEQLWFFW 209
Cdd:pfam00230 160 LGTVAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWKW--DDHWVYW 209
PLN00184 PLN00184
aquaporin NIP1; Provisional
 2-208 4.69e-34

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 123.59  E-value: 4.69e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    2 FRKLAAECFGTFWLVFGGCGSAVLAAGFPELgIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEV 81
Cdd:PLN00184  54 LQKLIAEVLGTYFLVFTGCASVVVNMQNDNV-VTLPGIAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASCGRFPLKQV 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   82 VGYVIAQVVGGIVAAALLYLIasgkTGFDAAASGFASNGYGEHSPGGySMLSALVVELVLSAGFLLVIHG-ATDKFAPAG 160
Cdd:PLN00184 133 PAYVISQVIGSTLAAATLRLL----FGLDHDVCSGKHDVFIGSSPVG-SDLQAFVMEFIVTFYLMFIISGvATDNRAIGE 207

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 15830215  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalEQLWFF 208
Cdd:PLN00184 208 LAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYGCY--KGIWIY 253
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 3-198 6.55e-28

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 106.92  E-value: 6.55e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    3 RKLAAECFGTFWLVFGGCGSAVLAAGFPElGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:PLN00182  43 QKLIAEMIGTYFIIFSGCGVVVVNVLYGG-TITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVP 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   83 GYVIAQVVGGIVAAALLYLIasgktgFDAAASGFASNgygehSPGGySMLSALVVELVLSAGFLLVIHG-ATDKFAPAGF 161
Cdd:PLN00182 122 LYIGAQLTGSLLASLTLRLM------FNVTPEAFFGT-----TPTD-SSGQALVAEIIISFLLMFVISGvATDSRAVGEL 189

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 15830215  162 APIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQG 198
Cdd:PLN00182 190 AGIAVGMTIILNVFVAGPISGASMNPARSLGPAIVMG 226
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 1-189 1.27e-20

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 87.87  E-value: 1.27e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    1 MFRKLAAECFGTFWLVFGGCGsAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:PTZ00016  49 NVREYVAEFLGTFVLLFFGEG-VVATTHTVGNNGDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWKK 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   81 VVGYVIAQVVGGIVAAALLYLIASGKtgFDAAASGFASNGYGEHSPGGY-------SMLSALVVELVLSAGFLLVIHGAT 153
Cdd:PTZ00016 128 LPGYFVAQLLGAFVGAACVYGLYYGF--FKDHGIPELPWETMANGFAGVfatypreGNFYAIFSELILTAILLLVILAIT 205

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 15830215  154 DK--FAPAGFAPIAIGLALTLIHLISIPVTNTSVNPAR 189
Cdd:PTZ00016 206 DPnnCPAFNYLPVAVGLLVFVIGISFGGNTGYALNPAR 243
PLN00026 PLN00026
aquaporin NIP; Provisional
 3-208 1.93e-19

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 84.53  E-value: 1.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    3 RKLAAECFGTFWLVFGGCGSAVLAAGF--PELGIGFAGVAlafGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE 80
Cdd:PLN00026  72 RKLGAEFVGTFILIFAATAGPIVNQKYdgAETLIGNAACA---GLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPWKH 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   81 VVGYVIAQVVGGIVAAALLyliasgKTGFDAAASGfasngyGEHSPGGySMLSALVVELVLSAGFLLVIHG-ATDKFAPA 159
Cdd:PLN00026 149 VPAYIAAQVSASICASFAL------KGVFHPFMSG------GVTVPSV-STGQAFALEFIITFNLLFVVTAvATDTRAVG 215

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 15830215  160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalEQLWFF 208
Cdd:PLN00026 216 ELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAGNY--RAIWIY 262
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 3-208 4.44e-19

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 83.37  E-value: 4.44e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    3 RKLAAECFGTFWLVFGGCG---SAVLAAGfpelGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAK 79
Cdd:PLN00183  46 RMVLAEMVGTFILMFCVCGiiaSTQLSGG----EVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWS 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   80 EVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNgygehspggysmlSALVVELVlsAGFLLVIHGATDKFAPA 159
Cdd:PLN00183 122 KVPLYITAQTVGSVLATYVGVSVYGVKADLMTTKPAQGCS-------------SAFWVEFI--ATFIVMFLAASLTSQPQ 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 15830215  160 GFAPIA---IGLALTLIHLISIPVTNTSVNPARSTAVAIFqgGWALEQLWFF 208
Cdd:PLN00183 187 SLGHLSgfvIGIAIGLAVLITGPVSGGSMNPARSLGPAIV--SWDFKDIWIY 236
PLN00166 PLN00166
aquaporin TIP2; Provisional
 7-209 2.67e-14

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 69.97  E-value: 2.67e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    7 AECFGTFWLVFGGCGSAVLAAGFPELGI----GFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVV 82
Cdd:PLN00166  23 SEFIATLLFVFAGVGSAIAFAKLTSDAAldpaGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAIGGNITIITGF 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   83 GYVIAQVVGGIVAAALLYLIASGKTgfdAAASGFASngygehspgGYSMLSALVVELVLSAGFLLVIHGAT---DKFAPA 159
Cdd:PLN00166 103 FYWIAQCLGSIVACLLLVFVTNGES---VPTHGVAA---------GLGAIEGVVMEIVVTFALVYTVYATAadpKKGSLG 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 15830215  160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGwaLEQLWFFW 209
Cdd:PLN00166 171 TIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGD--FSQIWIYW 218
PLN00027 PLN00027
aquaporin TIP; Provisional
 2-209 2.73e-10

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 58.64  E-value: 2.73e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    2 FRKLAAECFGTFWLVFGGCGSAVL------AAGFPELGIGFAGVALAFGLTVltmAFAVG-HISGGHFNPAVTIGLWAGG 74
Cdd:PLN00027  20 LKAALAEFISTLIFVFAGEGSGMAfnkltdNGSTTPAGLVAAALAHAFALFV---AVSVGaNISGGHVNPAVTFGAFIGG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   75 RFPAKEVVGYVIAQVVGGIVAAALLYLIASGktgfdAAASGFASNgygehspGGYSMLSALVVELVLSAGFLLVIHG-AT 153
Cdd:PLN00027  97 NITLLRGILYWIAQLLGSVVACLLLKFSTGG-----LETSAFSLS-------SGVGVWNAFVFEIVMTFGLVYTVYAtAV 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 15830215  154 D--KFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalEQLWFFW 209
Cdd:PLN00027 165 DpkKGDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVVSWTW--TNHWVYW 220
PLN00167 PLN00167
aquaporin TIP5; Provisional
 2-198 6.68e-09

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 54.52  E-value: 6.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215    2 FRKLAAECFGTFWLVFGGCGSAV----LAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFP 77
Cdd:PLN00167  22 LRSYLAEFISTFFFVFAAVGSAMssrkLMPDAASDPSSLLIVAIANAFALSSAVYIAANISGGHVNPAVTFGMAVGGHIS 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15830215   78 AKEVVGYVIAQVVGGIVAAALL-----------YLIASGKTGFDAAasgfasngygehspggysmlsalVVELVLSAGFL 146
Cdd:PLN00167 102 VPTAMFYWISQMLASVMACLFLkvttvgqhvptYKIAEEMTGFGAS-----------------------VLEGVLTFGLV 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15830215  147 LVIHGATD--KFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQG 198
Cdd:PLN00167 159 YTVYAAGDprRGLLGAIGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAG 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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