|
Name |
Accession |
Description |
Interval |
E-value |
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
7-427 |
1.08e-110 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 332.65 E-value: 1.08e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 7 FPQSFFARTLWLV----LIVVLFSKALTLVY------------------LLMNEDVIVDRQYSHGAALTiRAFWAADEES 64
Cdd:PRK09467 4 SPRSSFARTLLLIvtllFISQVVSYLVVLNYailpslqqfnkvlayevrLLFTDQLEDGTQLVVPPAFR-REIYRELGIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 65 --RAAIAKASGLRWVpssadqpgeQHWPYTEifqRQMQMELGPDTETRLRIHQPSQ-LWVRAPSLGEGWLAVPLYPHplr 141
Cdd:PRK09467 83 lySNEAAEEAGLRWA---------QHYEFLS---EQMSQQLGGPTEVRVEVGKESPiVWIKTPLAPNIWVRVPLTEI--- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 142 GQRIWSVLGWF-LGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGrSVRLPLGPETPSEMAEVYRAFNQMAEDIEQGG 220
Cdd:PRK09467 148 HQGDFSPLFRYtLAIGLLSVAGGWLFIRIQNRPLVALEHAALQVGKG-EIPPPLREYGASEVRSVTRAFNQMAAGIKQLE 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 221 RERELMLAGVSHDLRTPLTRLRLSLELLPESEREMVEDMIRDIEDMDAILDQFLAFIRDGRDEPVEEGDLTDLVREVVAP 300
Cdd:PRK09467 227 DDRTLLMAGVSHDLRTPLTRIRLATEMMSEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNALLGEVIAA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 301 FNQTREQVRMALQPVP-AMPLRRVSMKRLLGNLIDNALNHGGGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIF 379
Cdd:PRK09467 307 ESGYEREIETALQPGPiEVPMNPIAIKRALANLVVNAARYGNGWIKVSSGTEGK----RAWFQVEDDGPGIPPEQLKHLF 382
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 15600392 380 NPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARVC 427
Cdd:PRK09467 383 QPFTRGDSARGSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAW 430
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
130-426 |
2.55e-53 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 181.26 E-value: 2.55e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 130 WLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGRSVRLPLGPETPSEMAEVYRAF 209
Cdd:COG0642 17 LLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 210 NQMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLELL----PESEREMVEDMIRDIEDMDAILDQFLAF--IRDGRDE 283
Cdd:COG0642 97 LALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLleelDEEQREYLETILRSADRLLRLINDLLDLsrLEAGKLE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 284 P-VEEGDLTDLVREVVAPFNQTREQVRMALQ-----PVPAMPLRRVSMKRLLGNLIDNALNHG--GGSVEVASYVAGEsa 355
Cdd:COG0642 177 LePEPVDLAELLEEVVELFRPLAEEKGIELEldlpdDLPTVRGDPDRLRQVLLNLLSNAIKYTpeGGTVTVSVRREGD-- 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600392 356 apYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:COG0642 255 --RVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTV 323
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
208-426 |
1.31e-52 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 176.25 E-value: 1.31e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 208 AFNQMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLELL-------PESEREMVEDMIRDIEDMDAILDQFLAFIR-- 278
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLldeedlsPEERRELLEIIRESAERLLRLIEDLLDLSRle 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 279 DGRDEP-VEEGDLTDLVREVVAPFNQTREQVRMALQ-----PVPAMPLRRVSMKRLLGNLIDNALNHG--GGSVEVASYV 350
Cdd:COG2205 81 SGKLSLeLEPVDLAELLEEAVEELRPLAEEKGIRLEldlppELPLVYADPELLEQVLANLLDNAIKYSppGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15600392 351 AGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:COG2205 161 EGD----GVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTV 232
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-427 |
1.15e-49 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 163.77 E-value: 1.15e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHGGGSVEVASYVAGesaaPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRI 404
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEG----NRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGTGLGLAIVQRI 76
|
90 100
....*....|....*....|...
gi 15600392 405 AAQHGGSVELRNRDGGGLEARVC 427
Cdd:cd16950 77 SDAHGGSLTLANRAGGGLCARIE 99
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
121-426 |
1.69e-46 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 165.11 E-value: 1.69e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 121 VRAPSLGEGWLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGRSVRLPLGPETPS 200
Cdd:COG5002 56 LLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLS 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 201 E-------MAEVYRAFNQMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLELL-------PESEREMVEDMIRDIEDM 266
Cdd:COG5002 136 LrlsalllGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLldgaaddPEERREYLEIILEEAERL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 267 DAILDQFLAFIR-DGRDEPV--EEGDLTDLVREVVAPFNQTREQVRMALQ-PVPAMPLR----RVSMKRLLGNLIDNALN 338
Cdd:COG5002 216 SRLVNDLLDLSRlESGELKLekEPVDLAELLEEVVEELRPLAEEKGIELElDLPEDPLLvlgdPDRLEQVLTNLLDNAIK 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 339 HG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQHGGSVEL 414
Cdd:COG5002 296 YTpeGGTITVSLREEDD----QVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSREtgGTGLGLAIVKHIVEAHGGRIWV 371
|
330
....*....|..
gi 15600392 415 RNRDGGGLEARV 426
Cdd:COG5002 372 ESEPGKGTTFTI 383
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
136-427 |
2.80e-40 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 148.98 E-value: 2.80e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 136 YPHPLRgqriWSVLGWFLGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLPLGPEtpSEMAEVYRAFNQMAE 214
Cdd:PRK10604 130 YLHQMR----LLDIALLALIGLSLAFPVFLWMRPHWQDMLKLEAAAQRLGDGHlAERIHFDEG--SSLERLGVAFNQMAD 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 215 DIEQGGRERELMLAGVSHDLRTPLTRLRLSLEL---LPESEREMVEdmiRDIEDMDAILDQFLAFIRDGRDE---PVEEG 288
Cdd:PRK10604 204 NINALIASKKQLIDGIAHELRTPLVRLRYRLEMsdnLSAAESQALN---RDIGQLEALIEELLTYARLDRPQnelHLSEP 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 289 DLTDLVREVVAPFNQTREQVRMALQPVPAMPLRRVS---MKRLLGNLIDNALNHGGGSVEVASYVAGESAapyvVLSVLD 365
Cdd:PRK10604 281 DLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDmrlMERVLDNLLNNALRYAHSRVRVSLLLDGNQA----CLIVED 356
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600392 366 RGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQHGGSVELRNRDGGGleARVC 427
Cdd:PRK10604 357 DGPGIPPEERERVFEPFVRLDPSRDRAtgGCGLGLAIVHSIALAMGGSVNCDESELGG--ARFS 418
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
226-427 |
9.24e-36 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 136.63 E-value: 9.24e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 226 MLAGVSHDLRTPLTRLRLSLELL-----------PESEREMVEDMIRDIEDMDAILDQFLAFIRDGRDEPvEEGDLTDLV 294
Cdd:COG5000 204 LARRIAHEIKNPLTPIQLSAERLrrkladkleedREDLERALDTIIRQVDRLKRIVDEFLDFARLPEPQL-EPVDLNELL 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 295 REVVAPFNQTREQVRMALQ-----PVPAMPLRRVSMKRLLGNLIDNALN--HGGGSVEVASYVAGEsaapYVVLSVLDRG 367
Cdd:COG5000 283 REVLALYEPALKEKDIRLEldldpDLPEVLADRDQLEQVLINLLKNAIEaiEEGGEIEVSTRREDG----RVRIEVSDNG 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 368 QGIDPAEVDSIFNPFIRGDKarggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARVC 427
Cdd:COG5000 359 PGIPEEVLERIFEPFFTTKP----KGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIR 414
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
143-427 |
1.65e-34 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 133.82 E-value: 1.65e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 143 QRIWSVLGWFLGIGLLSTAA-AWIFVRqlsqPLKRLVVAARQFGQGRSVRLPLGPetPSEMAEVYRAFNQMaedieqggR 221
Cdd:PRK11100 182 RRILWAGALLLGIALLIGAGvVWWLNR----SIRRLTRYADAVTEGKPVPLPKLG--SSELRELAQALESM--------R 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 222 ERelmLAG----------VSHDLRTPLTRLRLSLELL----PESEREMVEDMIRD-IEDMDAILDQFLAFIR---DGRDE 283
Cdd:PRK11100 248 VK---LEGkayveqyvqtLTHELKSPLAAIRGAAELLqedpPPEDRARFTGNILTqSARLQQLIDRLLELARleqRQELE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 284 PVEEGDLTDLVREVVAPFNQTREQ--VRMALQPVPA-MPLRRVSMKRLLGNLIDNALN--HGGGSVEVASYVAGEsaapY 358
Cdd:PRK11100 325 VLEPVALAALLEELVEAREAQAAAkgITLRLRPDDArVLGDPFLLRQALGNLLDNAIDfsPEGGTITLSAEVDGE----Q 400
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15600392 359 VVLSVLDRGQGI-DPAeVDSIFNPFI---RGDKARggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARVC 427
Cdd:PRK11100 401 VALSVEDQGPGIpDYA-LPRIFERFYslpRPANGR--KSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLT 470
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
153-426 |
2.70e-32 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 128.22 E-value: 2.70e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 153 LGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLPLGPEtpSEMAEVYRAFNQMAEDIEQGGRERELM----- 226
Cdd:NF040691 195 LALVVLLGLIAWLVTRQVVAPVRSAARTAERFAAGDlSERMPVKGE--DDLARLARSFNQMADSLQRQIRQLEELsrlqq 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 227 --LAGVSHDLRTPLTRLRLSLELLPESEREM-------VEDMIRDIEDMDAILDQFLAFIR--DGRDE-PVEEGDLTDLV 294
Cdd:NF040691 273 rfVSDVSHELRTPLTTIRMAADVIHDSRDDFdpatarsAELLHTELDRFESLLSDLLEISRfdAGAAElDVEPVDLRPLV 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 295 REVVAPFNQTREQ------VRMALQPVPA-MPLRRVsmKRLLGNLIDNALNHGGGS-VEVAsyVAGESAApyVVLSVLDR 366
Cdd:NF040691 353 RRVVDALRQLAERagvelrVDAPGTPVVAeVDPRRV--ERVLRNLVVNAIEHGEGKpVVVT--VAQDDTA--VAVTVRDH 426
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15600392 367 GQGIDPAEVDSIFNPFIRGD--KARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:NF040691 427 GVGLKPGEVALVFDRFWRADpaRARTTGGTGLGLAIALEDARLHGGWLEAWGRPGQGSQFRL 488
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
226-426 |
3.89e-32 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 125.30 E-value: 3.89e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 226 MLAGVSHDLRTPLT---------RLRLSLELLPESEREMVEDMIRDIEDMDAILDQFLAFIRDGRDEPvEEGDLTDLVRE 296
Cdd:COG4191 145 LAAGIAHEINNPLAailgnaellRRRLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEER-EPVDLNELIDE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 297 VVA----PFNQTREQVRMALQP-VPAMPLRRVSMKRLLGNLIDNAL----NHGGGSVEVASYVAGEsaapYVVLSVLDRG 367
Cdd:COG4191 224 ALEllrpRLKARGIEVELDLPPdLPPVLGDPGQLEQVLLNLLINAIdameEGEGGRITISTRREGD----YVVISVRDNG 299
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600392 368 QGIDPAEVDSIFNPFI--RgdkaRGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:COG4191 300 PGIPPEVLERIFEPFFttK----PVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTI 356
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
325-426 |
4.66e-31 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 114.62 E-value: 4.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVK 402
Cdd:cd00075 1 LEQVLSNLLDNALKYSppGGTIEISLRQEGD----GVVLEVEDNGPGIPEEDLERIFERFYRGDKSREGGGTGLGLAIVR 76
|
90 100
....*....|....*....|....
gi 15600392 403 RIAAQHGGSVELRNRDGGGLEARV 426
Cdd:cd00075 77 RIVEAHGGRITVESEPGGGTTFTV 100
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
3-421 |
2.65e-30 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 122.59 E-value: 2.65e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 3 TPLWFPQSFFARTLWLVLIVVLFSKALTLVYLLMNEDVIVDRQYSHGAALTIRAFWAADEESRAAIAKASGLRWVPSSAD 82
Cdd:COG4251 70 LLLLVLAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALAL 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 83 QPGEQHWPYTEIFQRQMQMELGPDTETRLRIHQPSQLWVRAPSLGEGWLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAA 162
Cdd:COG4251 150 LLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLL 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 163 AWIFVRQLSQPLKRLVVAARQFGQGRSVRLplgpetpsEMAEVYRAFNQMAEDIEQGGRERELMLAGVSHDLRTPLTRLR 242
Cdd:COG4251 230 LLLLLLVLLLLLILLLLLLILVLELLELRL--------ELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKIS 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 243 LSLELL--------PESEREMVEDMIRDIEDMDAILDQFLAFIRDGRDE-PVEEGDLTDLVREVVAPFNQTREQ--VRMA 311
Cdd:COG4251 302 GFSQLLeedygdklDEEGREYLERIRDAAERMQALIDDLLAYSRVGRQElEFEPVDLNELLEEVLEDLEPRIEErgAEIE 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 312 LQPVPAMPLRRVSMKRLLGNLIDNALNHGGGSVEVASYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGG 391
Cdd:COG4251 382 VGPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEY 461
|
410 420 430
....*....|....*....|....*....|
gi 15600392 392 KGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:COG4251 462 EGTGIGLAIVKKIVERHGGRIWVESEPGEG 491
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
138-419 |
9.22e-29 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 117.49 E-value: 9.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 138 HPLRGQRIWSVLGWFLGIgLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLPLGPeTPSEMAEVYRAFNQMAEDI 216
Cdd:TIGR01386 157 HLLDALRKWLILIAVLLV-LLTALLGWWITRLGLEPLRRLSAVAARISPESlDQRLDPSR-APAELRELAQSFNAMLGRL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 217 EQGGRERELMLAGVSHDLRTPLTRL------RLSLELLPESEREMVEDMIRDIEDMDAILDQ--FLAFIRDGRDEP-VEE 287
Cdd:TIGR01386 235 EDAFQRLSQFSADLAHELRTPLTNLlgqtqvALSQPRTGEEYREVLESNLEELERLSRMVSDmlFLARADNGQLALeRVR 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 288 GDLTDLVREVVAPFNQTREQ--VRMALQPVPAMPLRRVSMKRLLGNLIDNALNHG--GGSVEvasyVAGESAAPYVVLSV 363
Cdd:TIGR01386 315 LDLAAELAKVAEYFEPLAEErgVRIRVEGEGLVRGDPQMFRRAISNLLSNALRHTpdGGTIT----VRIERRSDEVRVSV 390
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 15600392 364 LDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQHGGSVELRNRDG 419
Cdd:TIGR01386 391 SNPGPGIPPEHLSRLFDRFYRVDPARSNSgeGTGLGLAIVRSIMEAHGGRASAESPDG 448
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
212-421 |
2.85e-28 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 114.56 E-value: 2.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 212 MAEDIEQGGR-EREL-----------MLAGVSHDLRTPLTRLRLSLELL-----PESEREMVEDMIRDIEDMDAILDQFL 274
Cdd:COG3852 112 VLRDITERKRlERELrraeklaavgeLAAGLAHEIRNPLTGIRGAAQLLerelpDDELREYTQLIIEEADRLNNLVDRLL 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 275 AFIRDGRDEPvEEGDLTDLVREVVAPFNQTRE---QVRMALQP-VPAMPLRRVSMKRLLGNLIDNALN--HGGGSVEVAS 348
Cdd:COG3852 192 SFSRPRPPER-EPVNLHEVLERVLELLRAEAPkniRIVRDYDPsLPEVLGDPDQLIQVLLNLVRNAAEamPEGGTITIRT 270
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 349 YVA------GESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGdKargGKGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:COG3852 271 RVErqvtlgGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTT-K---EKGTGLGLAIVQKIVEQHGGTIEVESEPGKG 345
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
224-426 |
1.99e-25 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 108.90 E-value: 1.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 224 ELMlAGVSHDLRTPLTRLRLSLELLPESE-----REMVEDMIRDIEDMDAILDQFLAFIRDgRDEPVEEGDLTDLVREVV 298
Cdd:PRK11360 392 ELV-AGVAHEIRNPLTAIRGYVQIWRQQTsdppsQEYLSVVLREVDRLNKVIDQLLEFSRP-RESQWQPVSLNALVEEVL 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 299 APFN----QTREQVRMALQP-VPAMPLRRVSMKRLLGNLIDNALN--HGGGSVEVASYVAGESAapyVVLSVLDRGQGID 371
Cdd:PRK11360 470 QLFQtagvQARVDFETELDNeLPPIWADPELLKQVLLNILINAVQaiSARGKIRIRTWQYSDGQ---VAVSIEDNGCGID 546
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 15600392 372 PAEVDSIFNPFIRgDKArggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:PRK11360 547 PELLKKIFDPFFT-TKA---KGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTL 597
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
325-426 |
2.31e-25 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 99.65 E-value: 2.31e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDK-ARGGKGTGLGLAIV 401
Cdd:smart00387 6 LRQVLSNLLDNAIKYTpeGGRITVTLERDGD----HVEITVEDNGPGIPPEDLEKIFEPFFRTDKrSRKIGGTGLGLSIV 81
|
90 100
....*....|....*....|....*
gi 15600392 402 KRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:smart00387 82 KKLVELHGGEISVESEPGGGTTFTI 106
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
157-422 |
9.50e-24 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 103.09 E-value: 9.50e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 157 LLSTAAAWIFVRQLSQPLKRLVVAARQFGQGRSVRLPLGPETPSEMAEVYRAFNQMAEDIEQ--GGRERelMLAGVSHDL 234
Cdd:PRK09470 177 LVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELETGPQEFRQAGASFNQMVTALERmmTSQQR--LLSDISHEL 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 235 RTPLTRLRLSLELL-------PESER-----EMVEDMIRDIedmdaildqfLAFIRDGRDEPV--EEGDLTDLVREVV-- 298
Cdd:PRK09470 255 RTPLTRLQLATALLrrrqgesKELERieteaQRLDSMINDL----------LVLSRNQQKNHLerETFKANSLWSEVLed 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 299 APFNQtrEQVRMALQpVPAMPLR------RVSMKRLLGNLIDNALNHGGGSVEVASYVAGEsaapYVVLSVLDRGQGIDP 372
Cdd:PRK09470 325 AKFEA--EQMGKSLT-VSAPPGPwpingnPNALASALENIVRNALRYSHTKIEVAFSVDKD----GLTITVDDDGPGVPE 397
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 15600392 373 AEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQHGGSVELRNRDGGGL 422
Cdd:PRK09470 398 EEREQIFRPFYRVDEARDREsgGTGLGLAIVENAIQQHRGWVKAEDSPLGGL 449
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
164-426 |
1.00e-23 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 101.58 E-value: 1.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 164 WIFVRQLSQPLKRLvvaaRQFGQGRSVR----LPLGPETPsEMAEVYRAFNQM----AEDIEQggrEReLMLAGVSHDLR 235
Cdd:PRK10755 79 FQAVRWITRPLAEL----QKELEARTADnltpIAIHSSTL-EIEAVTSALNQLvsrlTSTLDQ---ER-LFTADVAHELR 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 236 TPLTRLRLSLELLPESEREMVEDMIRDIEDMDAILDQFLAFIRDGRD------EPVeegdltDLVREVVAPFN------- 302
Cdd:PRK10755 150 TPLAGIRLHLELLEKQHHIDVAPLIARLDQMMHTVEQLLQLARAGQSfssghyQTV------KLLEDVILPSQdelseml 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 303 QTREQvRMALQPVPAMPLRR---VSMKRLLGNLIDNALNHG--GGSVEVASyvagESAAPYVVLSVLDRGQGIDPAEVDS 377
Cdd:PRK10755 224 EQRQQ-TLLLPESAADITVQgdaTLLRLLLRNLVENAHRYSpeGSTITIKL----SQEDGGAVLAVEDEGPGIDESKCGE 298
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 15600392 378 IFNPFIRGDKaRGGkGTGLGLAIVKRIAAQHGGSVELRNR-DGGGLEARV 426
Cdd:PRK10755 299 LSKAFVRMDS-RYG-GIGLGLSIVSRITQLHHGQFFLQNRqERSGTRAWV 346
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
227-413 |
7.41e-23 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 98.82 E-value: 7.41e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 227 LAGVSHDLRTPLTRLRLSLELL-------PESEREMVEDMIRDIEDMDAILDQFLAFIR------DGRDEPVEEGDLTDL 293
Cdd:TIGR02966 118 VANVSHELRTPLTVLRGYLETLadgpdedPEEWNRALEIMLEQSQRMQSLVEDLLTLSRlesaasPLEDEPVDMPALLDH 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 294 VREVVAPFNQTRE-QVRMALQPVPAM-----PLRRVsmkrlLGNLIDNALNHG--GGSVEVaSYVAGESAApyvVLSVLD 365
Cdd:TIGR02966 198 LRDEAEALSQGKNhQITFEIDGGVDVlgdedELRSA-----FSNLVSNAIKYTpeGGTITV-RWRRDGGGA---EFSVTD 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 15600392 366 RGQGIDPAEVDSIFNPFIRGDKARG--GKGTGLGLAIVKRIAAQHGGSVE 413
Cdd:TIGR02966 269 TGIGIAPEHLPRLTERFYRVDKSRSrdTGGTGLGLAIVKHVLSRHHARLE 318
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-426 |
3.88e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 90.46 E-value: 3.88e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 327 RLLGNLIDNALNHGGGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRI 404
Cdd:cd16949 3 RALENVLRNALRYSPSKILLDISQDGD----QWTITITDDGPGVPEDQLEQIFLPFYRVDSARDREsgGTGLGLAIAERA 78
|
90 100
....*....|....*....|..
gi 15600392 405 AAQHGGSVELRNRDGGGLEARV 426
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRI 100
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
322-426 |
1.00e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 89.73 E-value: 1.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 322 RVSMKRLLGNLIDNALNH----GGGSVEVasyvageSAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKaRGGKGTGLG 397
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHaakaGEITVTL-------SEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADK-RGGGGTGLG 74
|
90 100
....*....|....*....|....*....
gi 15600392 398 LAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:pfam02518 75 LSIVRKLVELLGGTITVESEPGGGTTVTL 103
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
212-413 |
3.03e-21 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 95.95 E-value: 3.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 212 MAEDIEQGGRERELML------------AGVSHDLRTPLTRLRLSLELLP---ESEREMVEDMIRDIEDMDAILDQFLAF 276
Cdd:COG5805 264 ILRDITEKKEAEELMArseklsiagqlaAGIAHEIRNPLTSIKGFLQLLQpgiEDKEEYFDIMLSELDRIESIISEFLAL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 277 IRDGRDEPVEEgDLTDLVREVVaPFNQTRE-----QVRM-ALQPVPAMPLRRVSMKRLLGNLIDNALNH--GGGSVEVAS 348
Cdd:COG5805 344 AKPQAVNKEKE-NINELIQDVV-TLLETEAilhniQIRLeLLDEDPFIYCDENQIKQVFINLIKNAIEAmpNGGTITIHT 421
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15600392 349 YVAGesaaPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKarggKGTGLGLAIVKRIAAQHGGSVE 413
Cdd:COG5805 422 EEED----NSVIIRVIDEGIGIPEERLKKLGEPFFTTKE----KGTGLGLMVSYKIIENHNGTID 478
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
151-427 |
6.81e-21 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 94.33 E-value: 6.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 151 WFLGIGLLSTAAAWIFVRQLSqPLKRLVVAARQFGQGRSVRLPLGpETPSEMAEVYRAFNQMAEDI-EQGGRERELMlAG 229
Cdd:PRK10337 167 WLVALPIMLIILMVLLGRELA-PLKKLALALRMRDPDSETPLNAT-GVPSEVRPLVEALNQLFARThAMMVRERRFT-SD 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 230 VSHDLRTPLTRLRLSLELL------PESEREMVEDMIRDIEDMDAILDQFLAFIR-DGRDEP--VEEGDLTDLVREVVAP 300
Cdd:PRK10337 244 AAHELRSPLAALKVQTEVAqlsdddPQARKKALLQLHAGIDRATRLVDQLLTLSRlDSLDNLqdVAEIPLEDLLQSAVMD 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 301 FNQTREQVRMALQ-PVPAMPLRRVSMKRLLG----NLIDNAL--NHGGGSVEVASYVAGesaapyvvLSVLDRGQGIDPA 373
Cdd:PRK10337 324 IYHTAQQAGIDVRlTLNAHPVIRTGQPLLLSllvrNLLDNAIrySPQGSVVDVTLNARN--------FTVRDNGPGVTPE 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 15600392 374 EVDSIFNPFIR--GDKArggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARVC 427
Cdd:PRK10337 396 ALARIGERFYRppGQEA---TGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
226-413 |
2.02e-20 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 93.50 E-value: 2.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 226 MLAGVSHDLRTPLTRLRLSLELLPES----EREMVEDMIRDIEDMDAILDQFLAF--IRDGRdepVEEGDLTDLVREVVA 299
Cdd:COG5809 273 LAAGIAHEIRNPLTSLKGFIQLLKDTideeQKTYLDIMLSELDRIESIISEFLVLakPQAIK---YEPKDLNTLIEEVIP 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 300 PF----NQTREQVRMAL-QPVPAMPLRRVSMKRLLGNLIDNALN--HGGGSVEVASYVAGESaapYVVLSVLDRGQGIDP 372
Cdd:COG5809 350 LLqpqaLLKNVQIELELeDDIPDILGDENQLKQVFINLLKNAIEamPEGGNITIETKAEDDD---KVVISVTDEGCGIPE 426
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 15600392 373 AEVDSIFNPFIrgdkARGGKGTGLGLAIVKRIAAQHGGSVE 413
Cdd:COG5809 427 ERLKKLGEPFY----TTKEKGTGLGLMVSYKIIEEHGGKIT 463
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-426 |
3.10e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 82.84 E-value: 3.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVAsyvagESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKaRGGKGTGLGLAIVK 402
Cdd:cd16940 14 LFLLLRNLVDNAVRYSpqGSRVEIK-----LSADDGAVIRVEDNGPGIDEEELEALFERFYRSDG-QNYGGSGLGLSIVK 87
|
90 100
....*....|....*....|....
gi 15600392 403 RIAAQHGGSVELRNRDGGGLEARV 426
Cdd:cd16940 88 RIVELHGGQIFLGNAQGGGLEAWV 111
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
157-422 |
3.48e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 89.31 E-value: 3.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 157 LLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLplgpeTPS---EMAEVYRAFNQMAEDIEQGGRERELMLAGVSH 232
Cdd:PRK10549 175 LLAALATFLLARGLLAPVKRLVEGTHKLAAGDfTTRV-----TPTsrdELGRLAQDFNQLASTLEKNEQMRRDFMADISH 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 233 DLRTPLTRLRLSLELLPESEREMVEDMIRDIEDMDAILDQF--------------LAFirdgRDEPVeegDLTDLVREVV 298
Cdd:PRK10549 250 ELRTPLAVLRGELEAIQDGVRKFTPESVASLQAEVGTLTKLvddlhqlslsdegaLAY----RKTPV---DLVPLLEVAG 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 299 APFNQTREQVRMALQ-------PVPAMPLRrvsMKRLLGNLIDNALNH--GGGSVEvasyVAGESAAPYVVLSVLDRGQG 369
Cdd:PRK10549 323 GAFRERFASRGLTLQlslpdsaTVFGDPDR---LMQLFNNLLENSLRYtdSGGSLH----ISAEQRDKTLRLTFADSAPG 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 15600392 370 IDPAEVDSIFNPFIR--GDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGL 422
Cdd:PRK10549 396 VSDEQLQKLFERFYRteGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGV 450
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
129-426 |
3.07e-18 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 86.61 E-value: 3.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 129 GWLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAAA----WIFVRQLSQPLKRLVVAARQFGQGRSVRLPLgpETPSEMAE 204
Cdd:COG2972 136 GWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLAlllsYLLSRSITRPIKRLKKAMKKVEKGDLVRLEV--SGNDEIGI 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 205 VYRAFNQMAEDIEQGGRERELmlagvshdlrtpLTRLRLSLELL-------P-------ESEREMVEdmIRDIEDMDAIL 270
Cdd:COG2972 214 LARSFNEMVERIKELIEEVYE------------LELEKKEAELKalqaqinPhflfntlNSIRWLAE--LEDPEEAEEML 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 271 DQFLAFIR----DGRDE-PVEEgDLtDLVREVVApFNQTR--EQVRMALQpVPAMPLRRVSMKRLLGNLIDNALNHG--- 340
Cdd:COG2972 280 EALSKLLRyslsKGDELvTLEE-EL-ELIKSYLE-IQKLRfgDRLEVEIE-IDEELLDLLIPKLILQPLVENAIEHGiep 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 341 ---GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFirgdkARGGKGTGLGLAIV-KRIAAQHGG--SVEL 414
Cdd:COG2972 356 kegGGTIRISIRKEGD----RLVITVEDNGVGMPEEKLEKLLEEL-----SSKGEGRGIGLRNVrERLKLYYGEeyGLEI 426
|
330
....*....|..
gi 15600392 415 RNRDGGGLEARV 426
Cdd:COG2972 427 ESEPGEGTTVTI 438
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
325-421 |
3.99e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 76.76 E-value: 3.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNAL---NHGggSVEVASYVAGESAAPYVV-LSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGL 398
Cdd:cd16922 1 LRQILLNLLGNAIkftEEG--EVTLRVSLEEEEEDGVQLrFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKygGTGLGL 78
|
90 100
....*....|....*....|...
gi 15600392 399 AIVKRIAAQHGGSVELRNRDGGG 421
Cdd:cd16922 79 AISKKLVELMGGDISVESEPGQG 101
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
214-421 |
6.87e-17 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 82.88 E-value: 6.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 214 EDIEQggrERELMLAGVSHDLRTPLTRLRLSLELL-----------P--------ESERemvedMIRDIED------MDA 268
Cdd:NF033092 366 EKIEQ---ERREFVANVSHELRTPLTTMRSYLEALadgawkdpelaPrflgvtqnETER-----MIRLVNDllqlsrMDS 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 269 ILDQFlafirdgRDEPVeegDLTDLVREVVAPFNqtreqvrMALQPVPAMPLRRVSMKRL------------LGNLIDNA 336
Cdd:NF033092 438 KDYKL-------NKEWV---NFNEFFNYIIDRFE-------MILKNKNITFKREFPKRDLwveidtdkitqvLDNIISNA 500
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 337 LNH--GGGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQHGGSV 412
Cdd:NF033092 501 IKYspEGGTITFRLLETHN----RIIISISDQGLGIPKKDLDKIFDRFYRVDKARSRKmgGTGLGLAIAKEVVEAHGGRI 576
|
....*....
gi 15600392 413 ELRNRDGGG 421
Cdd:NF033092 577 WAESEEGKG 585
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-421 |
1.50e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 74.77 E-value: 1.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHGGGSVEVASYVAGESAapyvVLSVLDRGQGIDPAEVDSIFNPFIRGD--KARGGKGTGLGLAIVK 402
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGRL----TLIVEDDGPGIPAAARERVFEPFVRLDpsRDRATGGFGLGLAIVH 76
|
90
....*....|....*....
gi 15600392 403 RIAAQHGGSVELRNRDGGG 421
Cdd:cd16939 77 RVALWHGGHVECDDSELGG 95
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
315-421 |
2.07e-16 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 80.66 E-value: 2.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 315 VPAMPLRRVSMKRLLGNLIDNALNH------GGGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNpfiRGDKA 388
Cdd:COG3290 272 LPDLPLSDTDLVTILGNLLDNAIEAveklpeEERRVELSIRDDGD----ELVIEVEDSGPGIPEELLEKIFE---RGFST 344
|
90 100 110
....*....|....*....|....*....|...
gi 15600392 389 RGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:COG3290 345 KLGEGRGLGLALVKQIVEKYGGTIEVESEEGEG 377
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-422 |
9.52e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 72.88 E-value: 9.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVASYVAGESAApyvvLSVLDRGQGIDPAEVDSIFNPFIRGDKARGG-KGTGLGLAIV 401
Cdd:cd16945 5 LRQAINNLLDNAIDFSpeGGLIALQLEADTEGIE----LLVFDEGSGIPDYALNRVFERFYSLPRPHSGqKSTGLGLAFV 80
|
90 100
....*....|....*....|.
gi 15600392 402 KRIAAQHGGSVELRNRDGGGL 422
Cdd:cd16945 81 QEVAQLHGGRITLRNRPDGVL 101
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
116-427 |
2.31e-15 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 78.53 E-value: 2.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 116 PSQLWVRAPSLGEGWLAVPLYPH---------PLRGQRIWSVLGWFLGIGLLStaaaWIFVRQLSQPLKRLVVAARQFGQ 186
Cdd:PRK15347 262 PDYLVLRTQLKGPGWQQVTLYPRrnlanealkPALQQLPFALLILVLLTSVLF----LLLRRYLAKPLWRFVDIINKTGP 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 187 -GRSVRLPLGPEtpSEMAEVYRAFNQMAEDI-------------------------EQGGRERELMLAGVSHDLRTPLTR 240
Cdd:PRK15347 338 aALEPRLPENRL--DELGSIAKAYNQLLDTLneqydtlenkvaertqalaeakqraEQANKRKSEHLTTISHEIRTPLNG 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 241 LRLSLELLPESERemvedmirDIEDMD-------------AILDQFLAFIRdgrdepVEEGDLTdLVREVVAPFN----- 302
Cdd:PRK15347 416 VLGALELLQNTPL--------TAEQMDladtarqctlsllAIINNLLDFSR------IESGQMT-LSLEETALLPlldqa 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 303 ----QTREQVR-MAL-----QPVPA-MPLRRVSMKRLLGNLIDNALN---HGGGSVEVasyvagESAAPYVVLSVLDRGQ 368
Cdd:PRK15347 481 mltiQGPAQSKsLTLrtfvgAHVPLyLHLDSLRLRQILVNLLGNAVKfteTGGIRLRV------KRHEQQLCFTVEDTGC 554
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 369 GIDPAEVDSIFNPFIRGDKARggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGleARVC 427
Cdd:PRK15347 555 GIDIQQQQQIFTPFYQADTHS--QGTGLGLTIASSLAKMMGGELTLFSTPGVG--SCFS 609
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
228-421 |
1.31e-14 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 75.59 E-value: 1.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 228 AGVSHDLRTPLTRLR-----LSLELLPESE-REMVEDMIRDIEDMDAILDQFLAFIRDGRDEPvEEGDLTDLVREVVAPF 301
Cdd:PRK10364 242 AGVAHEIRNPLSSIKglakyFAERAPAGGEaHQLAQVMAKEADRLNRVVSELLELVKPTHLAL-QAVDLNDLINHSLQLV 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 302 NQTREQVRMALQ--PVPAMPLRRVSMKRL---LGNLIDNALnHGGGSVEVASYVAGESAAPyVVLSVLDRGQGIDPAEVD 376
Cdd:PRK10364 321 SQDANSREIQLRftANDTLPEIQADPDRLtqvLLNLYLNAI-QAIGQHGVISVTASESGAG-VKISVTDSGKGIAADQLE 398
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 15600392 377 SIFNPFIrgdkARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK10364 399 AIFTPYF----TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKG 439
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
329-421 |
4.44e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 68.08 E-value: 4.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 329 LGNLIDNALNHGGGSVEVAS--YVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNpfiRGDKARGGKGTGLGLAIVKRIAA 406
Cdd:cd16915 5 VGNLIDNALDALAATGAPNKqvEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFE---RGVSTKGQGERGIGLALVRQSVE 81
|
90
....*....|....*
gi 15600392 407 QHGGSVELRNRDGGG 421
Cdd:cd16915 82 RLGGSITVESEPGGG 96
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
221-421 |
1.04e-13 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 73.53 E-value: 1.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 221 RE--RELMLAGVSHDLRTPLTRLR-----LSLELLPE--------SE-REMVEDMIRDIEDMdaiLDqfLAFIRDG---- 280
Cdd:PRK10490 660 REqlRNALLAALSHDLRTPLTVLFgqaeiLTLDLASEgspharqaSEiRQQVLNTTRLVNNL---LD--MARIQSGgfnl 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 281 RDE--PVEEgdltdLVREVVAPFNQTREQVRMALQPVPAMPLRRVS---MKRLLGNLIDNALNHGGGSVEVAsyVAGESA 355
Cdd:PRK10490 735 RKEwlTLEE-----VVGSALQMLEPGLSGHPINLSLPEPLTLIHVDgplFERVLINLLENAVKYAGAQAEIG--IDAHVE 807
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15600392 356 APYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK10490 808 GERLQLDVWDNGPGIPPGQEQLIFDKFARGNKESAIPGVGLGLAICRAIVEVHGGTIWAENRPEGG 873
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-421 |
2.04e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 66.29 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 322 RVSMKRLLGNLIDNALN--HGGGSVEVASYVAGESaapyVVLSVLDRGQGIDPAEVDSIFNPFIRGDKArgGKGTGLGLA 399
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQamEGRGRITIRTWAHVDQ----VLIEVEDTGSGIDPEILGRIFDPFFTTKPV--GEGTGLGLS 74
|
90 100
....*....|....*....|..
gi 15600392 400 IVKRIAAQHGGSVELRNRDGGG 421
Cdd:cd16943 75 LSYRIIQKHGGTIRVASVPGGG 96
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
322-421 |
2.69e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 66.02 E-value: 2.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 322 RVSMKRLLGNLIDNALNhgggSVEVASYVAGE-------SAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRgDKArggKGT 394
Cdd:cd16944 2 TTQISQVLTNILKNAAE----AIEGRPSDVGEvrirveaDQDGRIVLIVCDNGKGFPREMRHRATEPYVT-TRP---KGT 73
|
90 100
....*....|....*....|....*..
gi 15600392 395 GLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:cd16944 74 GLGLAIVKKIMEEHGGRISLSNREAGG 100
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-422 |
3.47e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 65.49 E-value: 3.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVK 402
Cdd:cd16923 1 LQRVFSNLLSNAIKYSpeNTRIYITSFLTDD----VVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIAK 76
|
90 100
....*....|....*....|
gi 15600392 403 RIAAQHGGSVELRNRDGGGL 422
Cdd:cd16923 77 AIIELHGGSASAEYDDNHDL 96
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-421 |
3.54e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 65.43 E-value: 3.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHGGGSVEVASYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRI 404
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREEYEGTGVGLAIVRKI 80
|
90
....*....|....*..
gi 15600392 405 AAQHGGSVELRNRDGGG 421
Cdd:cd16921 81 IERHGGRIWLESEPGEG 97
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
269-421 |
4.75e-13 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 71.25 E-value: 4.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 269 ILDQFLAFIR--DGRDEPVeegDLTDLVREVVApfnqtreQVRMALQP-------VPAMPLR----RVSMKRLLGNLIDN 335
Cdd:PRK13837 502 IIDQILAFGRkgERNTKPF---DLSELVTEIAP-------LLRVSLPPgveldfdQDQEPAVvegnPAELQQVLMNLCSN 571
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 336 ALN--HGGGSVEVASYVAGESAAP-----------YVVLSVLDRGQGIDPAEVDSIFNPFIrgdKARGGkGTGLGLAIVK 402
Cdd:PRK13837 572 AAQamDGAGRVDISLSRAKLRAPKvlshgvlppgrYVLLRVSDTGAGIDEAVLPHIFEPFF---TTRAG-GTGLGLATVH 647
|
170
....*....|....*....
gi 15600392 403 RIAAQHGGSVELRNRDGGG 421
Cdd:PRK13837 648 GIVSAHAGYIDVQSTVGRG 666
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
155-412 |
5.16e-13 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 70.57 E-value: 5.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 155 IGLLSTAAAWIFVRQLSQPLkRLVVAARQFGQGRSVRLPLGPET-PSEMAEVYRAFNQMAEDIEQGGRERELMLAGVSHD 233
Cdd:PRK09835 194 ISLLIVFIVLLAVHKGHAPI-RSVSRQIQNITSKDLDVRLDPQTvPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHE 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 234 LRTPLTRLRLSLELL---PESEREMVE----------DMIRDIEDMdaildQFLAFIRDGRDEPVEEG-DLTDLVREVVA 299
Cdd:PRK09835 273 IRTPITNLITQTEIAlsqSRSQKELEDvlysnleeltRMAKMVSDM-----LFLAQADNNQLIPEKKMlDLADEVGKVFD 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 300 PFNQTREQVRMALQPV---------PAMpLRRVsmkrlLGNLIDNALNH--GGGSVEVASyvagESAAPYVVLSVLDRGQ 368
Cdd:PRK09835 348 FFEAWAEERGVELRFVgdpcqvagdPLM-LRRA-----ISNLLSNALRYtpAGEAITVRC----QEVDHQVQLVVENPGT 417
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 15600392 369 GIDPAEVDSIFNPFIRGDKAR--GGKGTGLGLAIVKRIAAQHGGSV 412
Cdd:PRK09835 418 PIAPEHLPRLFDRFYRVDPSRqrKGEGSGIGLAIVKSIVVAHKGTV 463
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
200-421 |
1.09e-12 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 70.32 E-value: 1.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 200 SEMAEVYRAFNQMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLELLPE-----SEREMVEDMIRDIEDMDAILDQFL 274
Cdd:PRK11466 421 AELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADnpalnAQRDDLRAITDSGESLLTILNDIL 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 275 AF--IRDG------RDEPVEEGDLTDLVREVVAPFNQTR---------EQVRMALQPVPamplRRVsmKRLLGNLIDNAL 337
Cdd:PRK11466 501 DYsaIEAGgknvsvSDEPFEPRPLLESTLQLMSGRVKGRpirlatdiaDDLPTALMGDP----RRI--RQVITNLLSNAL 574
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 338 NHGG-GSVEVASYVAGESAapyvVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGgkGTGLGLAIVKRIAAQHGGSVELRN 416
Cdd:PRK11466 575 RFTDeGSIVLRSRTDGEQW----LVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG--GTGLGLTISSRLAQAMGGELSATS 648
|
....*
gi 15600392 417 RDGGG 421
Cdd:PRK11466 649 TPEVG 653
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
226-413 |
1.52e-12 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 68.74 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 226 MLAGVSHDLRTPLTRLR------LSLELLPESEREMVEDMIRDIEDMDAILDQFLAFIRDgRDEPVEEGDLTDLVREVV- 298
Cdd:COG5806 204 LAASIAHEVRNPLTVVRgfiqllQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKP-QPEKLEKIDVSEELEHVId 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 299 --APFnQTREQVRMALQPVPAMPLR--RVSMKRLLGNLIDNALN--HGGGSVEVASYVAGEsaapYVVLSVLDRGQGIDP 372
Cdd:COG5806 283 vlSPY-ANMNNVEIQTELEPGLYIEgdRQKLQQCLINIIKNGIEamPNGGTLTIDVSIDKN----KVIISIKDTGVGMTK 357
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 15600392 373 AEVDSIFNPFIrgdkARGGKGTGLGLAIVKRIAAQHGGSVE 413
Cdd:COG5806 358 EQLERLGEPYF----STKEKGTGLGTMVSYRIIEAMNGTIR 394
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
187-421 |
1.64e-12 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 68.88 E-value: 1.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 187 GRSVRLPLGPETPSEMAEVYRAFNQMaediEQGGRERELMLAGVSHDLRTPLTRLRLSLELLPESERE----------MV 256
Cdd:PRK11006 172 GRHLEIRVMPYTEGQLLMVARDVTQM----HQLEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEgalrekalhtMR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 257 EDMIRdiedMDAILDQFLAFirdGRDEPVEEGDLTDLV----------REVVAPFNQ----------------TREQVRM 310
Cdd:PRK11006 248 EQTQR----MEGLVKQLLTL---SKIEAAPTIDLNEKVdvpmmlrvleREAQTLSQGkhtitfevdnslkvfgNEDQLRS 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 311 ALQpvpamplrrvsmkrllgNLIDNALNH--GGGSVEVASYVAGESAapyvVLSVLDRGQGIDPAEVDSIFNPFIRGDKA 388
Cdd:PRK11006 321 AIS-----------------NLVYNAVNHtpEGTHITVRWQRVPQGA----EFSVEDNGPGIAPEHIPRLTERFYRVDKA 379
|
250 260 270
....*....|....*....|....*....|....*
gi 15600392 389 RGGK--GTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK11006 380 RSRQtgGSGLGLAIVKHALSHHDSRLEIESEVGKG 414
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-426 |
1.75e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 63.24 E-value: 1.75e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 331 NLIDNALNHGGGSVEVASYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKArgGKGTGLGLAIVKRIAAQHGG 410
Cdd:cd16976 7 NLLQNALDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPV--GKGTGLGLSISYGIVEEHGG 84
|
90
....*....|....*.
gi 15600392 411 SVELRNRDGGGLEARV 426
Cdd:cd16976 85 RLSVANEEGAGARFTF 100
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
325-421 |
2.42e-12 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 63.28 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNH--GGGSVevaSYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRG--DKARGGKGTGLGLAI 400
Cdd:cd16925 5 YERVVLNLLSNAFKFtpDGGRI---RCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGdgSSTRAHGGTGLGLSI 81
|
90 100
....*....|....*....|.
gi 15600392 401 VKRIAAQHGGSVELRNRDGGG 421
Cdd:cd16925 82 VKEFVELHGGTVTVSDAPGGG 102
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
324-417 |
4.45e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 62.92 E-value: 4.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 324 SMKRLLGNLIDNALNHGGGSVEVASYVAGESAapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGG--KGTGLGLAIV 401
Cdd:cd16947 20 ALQRILKNLISNAIKYGSDGKFLGMTLREDEK--HVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSakQGNGLGLTIT 97
|
90
....*....|....*.
gi 15600392 402 KRIAAQHGGSVELRNR 417
Cdd:cd16947 98 KRLAESMGGSIYVNSK 113
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
307-426 |
4.46e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 63.03 E-value: 4.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 307 QVRMALQPVPAMPLRRVSMKRLLGNLIDNALNHGGGSVEVASYVAgesaAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGD 386
Cdd:cd16954 20 SISLDISPELRFPGERNDLMELLGNLLDNACKWCLEFVEVTARQT----DGGLHLIVDDDGPGVPESQRSKIFQRGQRLD 95
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 15600392 387 KARGGKGtgLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:cd16954 96 EQRPGQG--LGLAIAKEIVEQYGGELSLSDSPLGGARFEV 133
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
221-278 |
7.21e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 60.30 E-value: 7.21e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600392 221 RERELMLAGVSHDLRTPLTRLRLSLELL------PESEREMVEDMIRDIEDMDAILDQFLAFIR 278
Cdd:cd00082 2 QAKGEFLANVSHELRTPLTAIRGALELLeeelldDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
222-278 |
1.06e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 59.89 E-value: 1.06e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15600392 222 ERELMLAGVSHDLRTPLTRLRLSLELL-----PESEREMVEDMIRDIEDMDAILDQFLAFIR 278
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLldtelSEEQREYLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
222-278 |
1.72e-11 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 59.53 E-value: 1.72e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15600392 222 ERELMLAGVSHDLRTPLTRLRLSLELL-----PESEREMVEDMIRDIEDMDAILDQFLAFIR 278
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLrdeklDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-422 |
1.81e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 57.86 E-value: 1.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNAL--NHGGGSVEVASyvageSAAPYVV-LSVLDRGQGIDPAEVDSIFNPFIRGD--KARGGKGTGLGLA 399
Cdd:cd16946 5 LQQLFVNLLENSLryTDTGGKLRIRA-----AQTPQEVrLDVEDSAPGVSDDQLARLFERFYRVEssRNRASGGSGLGLA 79
|
90 100
....*....|....*....|...
gi 15600392 400 IVKRIAAQHGGSVELRNRDGGGL 422
Cdd:cd16946 80 ICHNIALAHGGTISAEHSPLGGL 102
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-421 |
2.63e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 57.41 E-value: 2.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDN---ALNHGGGSVEVASYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKarggKGTGLGLAIV 401
Cdd:cd16920 1 IQQVLINLVRNgieAMSEGGCERRELTIRTSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKS----EGLGMGLSIC 76
|
90 100
....*....|....*....|
gi 15600392 402 KRIAAQHGGSVELRNRDGGG 421
Cdd:cd16920 77 RSIIEAHGGRLSVESPAGGG 96
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
143-427 |
3.25e-10 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 61.96 E-value: 3.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 143 QRIWSVLGWF---------LGIGLLSTAAAWIFvrqlsQPLKRLVVAARQFGQGRsvRLPLGPETPSEMAEVYRAFNQMA 213
Cdd:PRK10815 184 QRSYMVWSWFsyvllanllLVIPLLWLAAWWSL-----RPIEALAKQVRELEEGE--REQLDPNPPRELTSLVRNLNRLL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 214 EDieqggrERE------LMLAGVSHDLRTPLTRLRLSLELLpESEREM-VED----MIRDIEDMDAILDQFL--AFIRdg 280
Cdd:PRK10815 257 KN------ERErytkyrTTLTDLTHSLKTPLAVLQSTLRSL-RSGKQMsVEQaepiMLEQISRISQQIGYYLhrASMR-- 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 281 rdepveeGDLTDLVREV--VAP--------FNQT--REQVRMALQPVPAMPLrrVSMK----RLLGNLIDNALNHGGGSV 344
Cdd:PRK10815 328 -------SEHNLLSRELhsVAPlldnltsaLNKVyqRKGVNITLDISPEITF--VGEKndfmEVMGNVLDNACKYCLEFV 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 345 EVASYVAGESaapyVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKgtGLGLAIVKRIAAQHGGSVELRNRDGGGleA 424
Cdd:PRK10815 399 EISARQTDEH----LHIVVEDDGPGIPESKRELIFDRGQRADTLRPGQ--GLGLSVAREITEQYEGKISAGDSPLGG--A 470
|
...
gi 15600392 425 RVC 427
Cdd:PRK10815 471 RME 473
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-426 |
5.72e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 56.32 E-value: 5.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 327 RLLGNLIDNALNHG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKG-TGLGLAIVKR 403
Cdd:cd16975 7 RALINIISNACQYApeGGTVSISIYDEEE----YLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGhYGMGLYIAKN 82
|
90 100
....*....|....*....|...
gi 15600392 404 IAAQHGGSVELRNRDGGGLEARV 426
Cdd:cd16975 83 LVEKHGGSLIIENSQKGGAEVTV 105
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-425 |
1.28e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 55.66 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 327 RLLGNLIDNALNHGGGSVEVASYVAGESAAPYVVlSVLDRGQGIDPAEVDSIFNPFI--RGDKARGGKGTGLGLAIVKRI 404
Cdd:cd16953 3 QVLRNLIGNAISFSPPDTGRITVSAMPTGKMVTI-SVEDEGPGIPQEKLESIFDRFYteRPANEAFGQHSGLGLSISRQI 81
|
90 100
....*....|....*....|...
gi 15600392 405 AAQHGGSV--ELRNRDGGGLEAR 425
Cdd:cd16953 82 IEAHGGISvaENHNQPGQVIGAR 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-419 |
1.55e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 55.10 E-value: 1.55e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 361 LSVLDRGQGIDPAEVDSIFNPFIRGdkaRGGkGTGLGLAIVKRIAAQHGGSVELRNRDG 419
Cdd:cd16918 46 VSVIDNGPGIPPDLQDTIFYPMVSG---REN-GTGLGLAIAQNIVSQHGGVIECDSQPG 100
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
211-400 |
5.43e-09 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 58.45 E-value: 5.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 211 QMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLELL------PESEReMVEDM----------IRDIEDMDAILDQFL 274
Cdd:PRK10841 435 EMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLqtkelpKGVDR-LVTAMnnssslllkiISDILDFSKIESEQL 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 275 afirdgRDEPVEEGdltdlVREVVAPF--NQTREQVRMAL------QP-VPAM----PLRrvsMKRLLGNLIDNAL--NH 339
Cdd:PRK10841 514 ------KIEPREFS-----PREVINHItaNYLPLVVKKRLglycfiEPdVPVAlngdPMR---LQQVISNLLSNAIkfTD 579
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15600392 340 GGGSVeVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPF--IRGDKARGGKGTGLGLAI 400
Cdd:PRK10841 580 TGCIV-LHVRVDGD----YLSFRVRDTGVGIPAKEVVRLFDPFfqVGTGVQRNFQGTGLGLAI 637
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
358-426 |
9.47e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 53.15 E-value: 9.47e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 358 YVVLSVLDRGQGIDPAEVDSIFNPFIRGDKArgGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:cd16919 47 YVCLEVSDTGSGMPAEVLRRAFEPFFTTKEV--GKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRI 113
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-421 |
1.28e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 52.59 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 331 NLIDNALNHGGGSVEVA-SYVAGESAAPyvvLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK--GTGLGLAIVKRIAAQ 407
Cdd:cd16952 7 NLVSNAVKYTPPSDTITvRWSQEESGAR---LSVEDTGPGIPPEHIPRLTERFYRVDIERCRNtgGTGLGLAIVKHVMSR 83
|
90
....*....|....
gi 15600392 408 HGGSVELRNRDGGG 421
Cdd:cd16952 84 HDARLLIASELGKG 97
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
227-421 |
2.06e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 56.67 E-value: 2.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 227 LAGVSHDLRTPLTRLRLSLELLPESEREMvEDMIRDIEDMDAILDQFLAFIRDGRD-EPVEEG---------DLTDLVRE 296
Cdd:PRK09959 716 LATMSHEIRTPISSIMGFLELLSGSGLSK-EQRVEAISLAYATGQSLLGLIGEILDvDKIESGnyqlqpqwvDIPTLVQN 794
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 297 VVAPFNQTREQVRMALQPVPAMP---LRRV---SMKRLLGNLIDNALNHGG-GSVEVA-SYVAGESAAPYVVLSVLDRGQ 368
Cdd:PRK09959 795 TCHSFGAIAASKSIALSCSSTFPdhyLVKIdpqAFKQVLSNLLSNALKFTTeGAVKITtSLGHIDDNHAVIKMTIMDSGS 874
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 15600392 369 GIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK09959 875 GLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIG 927
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
211-410 |
2.65e-08 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 56.10 E-value: 2.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 211 QMAEDIEQGGRERELMLAGVSHDLRTPL------TRLRLSLELLPESEREM---------VEDMIRDIEDMDAI------ 269
Cdd:PRK11091 271 RYQDALEKASRDKTTFISTISHELRTPLngivglSRILLDTELTAEQRKYLktihvsaitLGNIFNDIIDMDKMerrklq 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 270 LD----QFLAFIrdgrdepveeGDLTDLVREVVAPfnqtrEQVRMALQPVPAMP---------LRRVsmkrlLGNLIDNA 336
Cdd:PRK11091 351 LDnqpiDFTDFL----------ADLENLSGLQAEQ-----KGLRFDLEPLLPLPhkvitdgtrLRQI-----LWNLISNA 410
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 337 L--NHGGGSVEVASYVAGESaapyVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGK---GTGLGLAIVKRIAAQHGG 410
Cdd:PRK11091 411 VkfTQQGGVTVRVRYEEGDM----LTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGGKpatGTGIGLAVSKRLAQAMGG 485
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-419 |
3.32e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 51.52 E-value: 3.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 325 MKRLLGNLIDNALNHG--GGSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKAR-GGKGTGLGLAIV 401
Cdd:cd16948 6 LSFIIGQIVSNALKYSkqGGKIEIYSETNEQ----GVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRnFQESTGMGLYLV 81
|
90 100
....*....|....*....|
gi 15600392 402 KRIAAQ--HGGSVELRNRDG 419
Cdd:cd16948 82 KKLCDKlgHKIDVESEVGEG 101
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
215-425 |
6.53e-08 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 54.68 E-value: 6.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 215 DIEQGGRERELMLA------GVSHDLRTPLTRLRLSLELLP---ESEREMVEDMIRDIEDMDAILD-------QFLAFIR 278
Cdd:PRK13557 149 DAEDALRQAQKMEAlgqltgGIAHDFNNLLQVMSGYLDVIQaalSHPDADRGRMARSVENIRAAAEraatltqQLLAFAR 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 279 ----DGRdePVeegDLTDLVREVVAPFNQTR-EQVRMALQPVPAMPLRRVSMKR----LLGNLID--NALNHGG------ 341
Cdd:PRK13557 229 kqrlEGR--VL---NLNGLVSGMGELAERTLgDAVTIETDLAPDLWNCRIDPTQaevaLLNVLINarDAMPEGGrvtirt 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 342 -----GSVEVASYvAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKArgGKGTGLGLAIVKRIAAQHGGSVELRN 416
Cdd:PRK13557 304 rnveiEDEDLAMY-HGLPPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKEE--GKGTGLGLSMVYGFAKQSGGAVRIYS 380
|
....*....
gi 15600392 417 RDGGGLEAR 425
Cdd:PRK13557 381 EVGEGTTVR 389
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
238-426 |
9.24e-08 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 53.08 E-value: 9.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 238 LTRLRLSLELL---PESEREMVEDMIRDIEDM-DAILDQFLAFIRDGRDEPVEEGDLTDLVREVVAPFNQTRE---QVRM 310
Cdd:COG4585 69 LSAIKLQLEAArrlLDADPEAAREELEEIRELaREALAELRRLVRGLRPPALDDLGLAAALEELAERLLRAAGirvELDV 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 311 ALQPVPAMPLRRVSMKRLLGNLIDNALNHGGGS-VEVASYVAGESaapyVVLSVLDRGQGIDPAEVdsifnpfirgdkar 389
Cdd:COG4585 149 DGDPDRLPPEVELALYRIVQEALTNALKHAGATrVTVTLEVDDGE----LTLTVRDDGVGFDPEAA-------------- 210
|
170 180 190
....*....|....*....|....*....|....*..
gi 15600392 390 ggKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEARV 426
Cdd:COG4585 211 --PGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRA 245
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
224-410 |
9.97e-08 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 53.80 E-value: 9.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 224 ELMLAGVSHDLRTPLTRLRLSLELL------PESEREMV------EDMIRDIEDMDAILDQFLAFIRdGRDE--PVE--E 287
Cdd:PRK09303 152 DRVLAMLAHDLRTPLTAASLALETLelgqidEDTELKPAlieqlqDQARRQLEEIERLITDLLEVGR-TRWEalRFNpqK 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 288 GDLTDLVREVVAPFN---QTREQ-----VRMALQPVPAMPLRrvsMKRLLGNLIDNALNH--GGGSVEVAsyvAGESAAP 357
Cdd:PRK09303 231 LDLGSLCQEVILELEkrwLAKSLeiqtdIPSDLPSVYADQER---IRQVLLNLLDNAIKYtpEGGTITLS---MLHRTTQ 304
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 15600392 358 YVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGG 410
Cdd:PRK09303 305 KVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTEGYGIGLSVCRRIVRVHYG 357
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
9-426 |
2.53e-07 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 53.19 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 9 QSFFARTLWLVLIVVLFSKALTLVYLLMNEDVIVDRQYSHGAALTIRAFWAADEESRAAIAKASGLRWVPSSADQPGEQH 88
Cdd:COG2770 75 LLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 89 WPYTEIFQRQMQMELGPDTETRLRIHQPSQLWVRAPSLGEGWLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAAAWIFVR 168
Cdd:COG2770 155 AALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLAR 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 169 QLSQPLKRLVVAARQFGQGR-SVRLPLgpETPSEMAEVYRAFNQMAEDIEQGGRERELMLAGVSHDLRTPLTRLRLSLEL 247
Cdd:COG2770 235 RITRPLRRLAEAARRIAAGDlDVRIPV--SRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLA 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 248 LPESEREMVEDMIRDIEDMDAILDQFLAFIRDGRDEPVEEGDLTDLVREVVAPFNQTREQVRMALQPVPAMPLRRVSMKR 327
Cdd:COG2770 313 LLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVL 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 328 LLGNLIDNALNHGGGSVEVASYVAGESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQ 407
Cdd:COG2770 393 ALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEAL 472
|
410
....*....|....*....
gi 15600392 408 HGGSVELRNRDGGGLEARV 426
Cdd:COG2770 473 LLLAALLLLAALGALELLL 491
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
171-216 |
9.13e-07 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 45.51 E-value: 9.13e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 15600392 171 SQPLKRLVVAARQFGQGR-SVRLPlgPETPSEMAEVYRAFNQMAEDI 216
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDlDVRVP--VRSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
168-218 |
1.14e-06 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 45.32 E-value: 1.14e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 15600392 168 RQLSQPLKRLVVAARQFGQGR-SVRLPlgPETPSEMAEVYRAFNQMAEDIEQ 218
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDlTVRLP--VDGRDEIGELARAFNEMADRLEE 50
|
|
| HAMP |
pfam00672 |
HAMP domain; |
165-218 |
1.25e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 45.31 E-value: 1.25e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 15600392 165 IFVRQLSQPLKRLVVAARQFGQGR-SVRLPlgPETPSEMAEVYRAFNQMAEDIEQ 218
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDlDVRLP--VSGRDEIGELARAFNQMAERLRE 53
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
39-425 |
1.69e-05 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 46.80 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 39 DVIVDRQYSHGAALTIRAFWAADEESRAAIAKASGLRWVPSSADQPGEQHWPYTEIFQRQMQMELGPDTETRLRIHQPSQ 118
Cdd:COG3850 11 LLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 119 LWVRAPSLGEGWLAVPLYPHPLRGQRIWSVLGWFLGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLPLgpE 197
Cdd:COG3850 91 SLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDfDARVPV--S 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 198 TPSEMAEVYRAFNQMAEDIEQ------GGRERELMLAGVSHDLRTPLTRLRLSLELLPESEREMVEDMIRDIEDMDAILD 271
Cdd:COG3850 169 GRDELGTLARAFNRMADELQElyaeleEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDAL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 272 QFLAFIRDGRDEPVEEGDLTDLVREVVAPFNQTREQVRMALQPVPAMPLRRVSMKRLLGNLIDNALNHGGGSVEVASYVA 351
Cdd:COG3850 249 AESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASL 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15600392 352 GESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKGTGLGLAIVKRIAAQHGGSVELRNRDGGGLEAR 425
Cdd:COG3850 329 LLIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAG 402
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
289-419 |
2.12e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.82 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 289 DLTDLVREVVAPFNQT----REQVRMALQPVP-----AMPLrrvSMkrLLGNLIDNALNHGGGSVEVAS-YVAGESAAPY 358
Cdd:COG3920 360 DLRDYLRELLEPLRDSyggrGIRIELDGPDVElpadaAVPL---GL--ILNELVTNALKHAFLSGEGGRiRVSWRREDGR 434
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600392 359 VVLSVLDRGQGIdPAEVDSifnpfirgdkargGKGTGLGLAIVKRIAAQHGGSVELRNRDG 419
Cdd:COG3920 435 LRLTVSDNGVGL-PEDVDP-------------PARKGLGLRLIRALVRQLGGTLELDRPEG 481
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
329-421 |
9.45e-05 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 44.52 E-value: 9.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 329 LGNLIDNAL----NHGGGSVEVA-SYVAGEsaapyVVLSVLDRGQGIDPAEVDSIFNpfirgdkaRG----GKGTGLGLA 399
Cdd:PRK11086 438 LGNLIENALeavgGEEGGEISVSlHYRNGW-----LHCEVSDDGPGIAPDEIDAIFD--------KGystkGSNRGVGLY 504
|
90 100
....*....|....*....|..
gi 15600392 400 IVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK11086 505 LVKQSVENLGGSIAVESEPGVG 526
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
335-420 |
2.11e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 41.05 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 335 NALNHGG-----GSVEVASYVAGEsaapYVVLSVLDRGQGIDPAEVDsifnpfirgDKARGGKGTGLGLAIVKRIAAQhg 409
Cdd:COG2172 45 NAVRHAYggdpdGPVEVELELDPD----GLEIEVRDEGPGFDPEDLP---------DPYSTLAEGGRGLFLIRRLMDE-- 109
|
90
....*....|.
gi 15600392 410 gsVELRNRDGG 420
Cdd:COG2172 110 --VEYESDPGG 118
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
327-419 |
3.13e-04 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 39.89 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 327 RLLGNLIDNAlnhgggsVEVASYVageSAAPYVVLSVLDRGQG-----IDPAEVDSIFNPFIRGDKARGGkGTGLGLAIV 401
Cdd:pfam14501 8 VIFGNLLDNA-------IEACSKI---DDNRFIRLKIREKQNFliiriENTYEGELKFEGKLPSTKTKGD-GHGIGLKSI 76
|
90
....*....|....*...
gi 15600392 402 KRIAAQHGGSVELRNRDG 419
Cdd:pfam14501 77 RRIVKKYGGNLSTEIENG 94
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
210-413 |
4.68e-04 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 41.99 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 210 NQMAEdiEQGGRErelMLAGVSHDLRTPLTRLRLSLELL----PE-SEREMVEDMIRDIEDMDAILDQFLAFIRDGRDEP 284
Cdd:PRK11073 122 LQHAQ--QVAARD---LVRGLAHEIKNPLGGLRGAAQLLskalPDpALTEYTKVIIEQADRLRNLVDRLLGPQRPGTHVT 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 285 VEEGDLTDLVREVVA---PFNQTREqvRMALQPVPAMPLRRVSMKRLLGNLIDNA---LNHGGGSVEVASYVA------G 352
Cdd:PRK11073 197 ESIHKVAERVVQLVSlelPDNVRLI--RDYDPSLPELAHDPDQIEQVLLNIVRNAlqaLGPEGGTITLRTRTAfqltlhG 274
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600392 353 ESAAPYVVLSVLDRGQGIDPAEVDSIFNPFIRGdkaRGGkGTGLGLAIVKRIAAQHGGSVE 413
Cdd:PRK11073 275 ERYRLAARIDIEDNGPGIPPHLQDTLFYPMVSG---REG-GTGLGLSIARNLIDQHSGKIE 331
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
227-421 |
1.32e-03 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 41.37 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 227 LAGVSHDLRTPL------TRLRLSLELLPeSERemveDMIRDIE----DMDAILDQFLAFIRdgrdepVEEG-------- 288
Cdd:PRK11107 297 LANMSHELRTPLngvigfTRQTLKTPLTP-TQR----DYLQTIErsanNLLAIINDILDFSK------LEAGklvlenip 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 289 -DLTDLVREVV---APFNQTR--EQVRMALQPVPAM----PLRrvsMKRLLGNLIDNALNHG-GGSVEVaSYVAGESAAP 357
Cdd:PRK11107 366 fSLRETLDEVVtllAHSAHEKglELTLNIDPDVPDNvigdPLR---LQQIITNLVGNAIKFTeSGNIDI-LVELRALSNT 441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 358 YVVL--SVLDRGQGIDPAEVDSIFNPFIRGDKA---RGGkGTGLGLAIVKRIAAQHGGSVELRNRDGGG 421
Cdd:PRK11107 442 KVQLevQIRDTGIGISERQQSQLFQAFRQADASisrRHG-GTGLGLVITQKLVNEMGGDISFHSQPNRG 509
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
328-421 |
2.08e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 40.20 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 328 LLGNLIDNALN------HGGGSVEVasYVAGESAApyVVLSVLDRGQGIDPAEVDSIFNPFIRGDKARGGKgTGLGLAIV 401
Cdd:PRK15053 436 IVGNLLDNAFEaslrsdEGNKIVEL--FLSDEGDD--VVIEVADQGCGVPESLRDKIFEQGVSTRADEPGE-HGIGLYLI 510
|
90 100
....*....|....*....|
gi 15600392 402 KRIAAQHGGSVELRNRDGGG 421
Cdd:PRK15053 511 ASYVTRCGGVITLEDNDPCG 530
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
146-275 |
2.24e-03 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 40.22 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600392 146 WSVLGWFLGIGLLSTAAAWIFV-----RQLSQPLKRLVVAARQFGQGRSVRLPLGPETPSEMAEVYRAFNQMAEDIEQGG 220
Cdd:PRK10935 147 LILLAAISLLGLILILTLVFFTvrftrRQVVAPLNQLVTASQQIEKGQFDHIPLDTTLPNELGLLAKAFNQMSSELHKLY 226
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 15600392 221 RERELMLAGVSHDlrtpLTRLRLSLELLPESEREMVEDMIrDIEDMDAILDQFLA 275
Cdd:PRK10935 227 RSLEASVEEKTRK----LTQANRSLEVLYQCSQALNASQI-DVHCFRHILQIVRD 276
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
151-218 |
2.29e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 40.39 E-value: 2.29e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600392 151 WFLGIGLLSTAAAWIFVRQLSQPLKRLVVAARQFGQGR-SVRLPLgpETPSEMAEVYRAFNQMAEDIEQ 218
Cdd:COG0840 187 ALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDlTVRIDV--DSKDEIGQLADAFNRMIENLRE 253
|
|
| |
