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Conserved domains on  [gi|226437669|ref|NP_081574|]
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coiled-coil domain-containing protein 89 [Mus musculus]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 100-368 4.60e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 4.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 100 KRLQEMEKLKAQSEHIQKLENHFMI-LASNHEQMIRFKDAHKSENVKLKEENARLRQENnslfsQALKDQEAKVLELTTL 178
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAeLAELEAELEELRLELEELELELEEAQAEEYELL-----AELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 179 NKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQ 258
Cdd:COG1196  311 RRELEERLEELEEELAELEEELEELEEELEELEEELE-EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 259 ARLQTVLREKEELLQLSMERgkvLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYD 338
Cdd:COG1196  390 EALRAAAELAAQLEELEEAE---EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                        250       260       270
                 ....*....|....*....|....*....|
gi 226437669 339 ELRLQSEAFKKHSLDLLSKERELNAKLRHL 368
Cdd:COG1196  467 ELLEEAALLEAALAELLEELAEAAARLLLL 496
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 100-368 4.60e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 4.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 100 KRLQEMEKLKAQSEHIQKLENHFMI-LASNHEQMIRFKDAHKSENVKLKEENARLRQENnslfsQALKDQEAKVLELTTL 178
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAeLAELEAELEELRLELEELELELEEAQAEEYELL-----AELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 179 NKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQ 258
Cdd:COG1196  311 RRELEERLEELEEELAELEEELEELEEELEELEEELE-EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 259 ARLQTVLREKEELLQLSMERgkvLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYD 338
Cdd:COG1196  390 EALRAAAELAAQLEELEEAE---EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                        250       260       270
                 ....*....|....*....|....*....|
gi 226437669 339 ELRLQSEAFKKHSLDLLSKERELNAKLRHL 368
Cdd:COG1196  467 ELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 36-340 5.36e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 5.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669    36 KEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEKRLQEMEKLKAQSEHI 115
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   116 QKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSL------FSQALKDQEAKVLELTTLNKALVEELEVL 189
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrealdeLRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   190 KQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQArLQTVLREKE 269
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIE-ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE-LESKRSELR 914

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 226437669   270 ELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAkKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYDEL 340
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 21-322 3.43e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   21 KQNENLQNQDEELgfKEMDGLREAlANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEK 100
Cdd:PTZ00121 1497 KKADEAKKAAEAK--KKADEAKKA-EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  101 RLQEMEKLKAQ-SEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELTTLN 179
Cdd:PTZ00121 1574 EDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  180 KAlVEELEVLKQRCAHEASQAQAREEELLGLQNQQ---ACDHAKETEELR--SQLQSIKQQHQQATEQMGKEQEANLNLN 254
Cdd:PTZ00121 1654 KA-EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEkkaAEALKKEAEEAKkaEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 226437669  255 QELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEE-KLETAAMAKKHALERFEQEAVAVDSNLR 322
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEiRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 100-368 4.60e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 4.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 100 KRLQEMEKLKAQSEHIQKLENHFMI-LASNHEQMIRFKDAHKSENVKLKEENARLRQENnslfsQALKDQEAKVLELTTL 178
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAeLAELEAELEELRLELEELELELEEAQAEEYELL-----AELARLEQDIARLEER 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 179 NKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQ 258
Cdd:COG1196  311 RRELEERLEELEEELAELEEELEELEEELEELEEELE-EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 259 ARLQTVLREKEELLQLSMERgkvLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYD 338
Cdd:COG1196  390 EALRAAAELAAQLEELEEAE---EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                        250       260       270
                 ....*....|....*....|....*....|
gi 226437669 339 ELRLQSEAFKKHSLDLLSKERELNAKLRHL 368
Cdd:COG1196  467 ELLEEAALLEAALAELLEELAEAAARLLLL 496
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 100-368 2.46e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 2.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 100 KRLQEMEKLKAQSEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELTTLN 179
Cdd:COG1196  216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 180 KalVEELEVLKQRCAHEASQAQAREEEL---LGLQNQQACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQE 256
Cdd:COG1196  296 E--LARLEQDIARLEERRRELEERLEELeeeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 257 LQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAmakKHALERFEQEAVAVDSNLRVRELQRRVDGIQKA 336
Cdd:COG1196  374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE---RLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                        250       260       270
                 ....*....|....*....|....*....|..
gi 226437669 337 YDELRLQSEAFKKHSLDLLSKERELNAKLRHL 368
Cdd:COG1196  451 EAELEEEEEALLELLAELLEEAALLEAALAEL 482
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
197-364 1.26e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.32  E-value: 1.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 197 ASQAQAREEELLGLQNQQAcdhaketeELRSQLQSIKQQHQQATEQMGKEQEANLNLN-----QELQARLQTVLREKEEL 271
Cdd:COG3206  211 SEEAKLLLQQLSELESQLA--------EARAELAEAEARLAALRAQLGSGPDALPELLqspviQQLRAQLAELEAELAEL 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 272 LQLSMERGKVLQNKQAEIRQLEEKLETaamakkhalerfEQEAVAVDSNLRVRELQRRVDGIQKAYDELRLQSEAFKKHS 351
Cdd:COG3206  283 SARYTPNHPDVIALRAQIAALRAQLQQ------------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE 350

                        170
                 ....*....|...
gi 226437669 352 LDLLSKERELNAK 364
Cdd:COG3206  351 AELRRLEREVEVA 363
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 17-332 3.23e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 3.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  17 EILGKQNENLQNQDEELGfKEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSE 96
Cdd:COG1196  284 EEAQAEEYELLAELARLE-QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  97 LEEKRLQEMEKLKAQSEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELT 176
Cdd:COG1196  363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 177 TLNKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQE 256
Cdd:COG1196  443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 226437669 257 LQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRRVDG 332
Cdd:COG1196  523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 36-340 5.36e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 5.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669    36 KEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEKRLQEMEKLKAQSEHI 115
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   116 QKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSL------FSQALKDQEAKVLELTTLNKALVEELEVL 189
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrealdeLRAELTLLNEEAANLRERLESLERRIAAT 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   190 KQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQArLQTVLREKE 269
Cdd:TIGR02168  837 ERRLEDLEEQIEELSEDIESLAAEIE-ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE-LESKRSELR 914

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 226437669   270 ELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAkKHALERFEQEAVAVDSNLRVRELQRRVDGIQKAYDEL 340
Cdd:TIGR02168  915 RELEELREKLAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 36-329 1.07e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  36 KEMDGLREALANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEKRLQEMEKLKAQSEHI 115
Cdd:COG1196  267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 116 QKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELTTLNKALVEELEVLKQRCAH 195
Cdd:COG1196  347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 196 EASQAQAREEELlgLQNQQACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQARLQTVLREKEELLQLS 275
Cdd:COG1196  427 EEALAELEEEEE--EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 226437669 276 MERGKVLQNKQAEIRQLEEKLETAAMAKKHALERFEQEAVAVDSNLRVRELQRR 329
Cdd:COG1196  505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558
PTZ00121 PTZ00121
MAEBL; Provisional
 21-322 3.43e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669   21 KQNENLQNQDEELgfKEMDGLREAlANLRGLSEEEKGEKAMLRSRIQEQSQLICILKRRSDEALERCQILELLNSELEEK 100
Cdd:PTZ00121 1497 KKADEAKKAAEAK--KKADEAKKA-EEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  101 RLQEMEKLKAQ-SEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALKDQEAKVLELTTLN 179
Cdd:PTZ00121 1574 EDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  180 KAlVEELEVLKQRCAHEASQAQAREEELLGLQNQQ---ACDHAKETEELR--SQLQSIKQQHQQATEQMGKEQEANLNLN 254
Cdd:PTZ00121 1654 KA-EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEkkaAEALKKEAEEAKkaEELKKKEAEEKKKAEELKKAEEENKIKA 1732

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 226437669  255 QELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEE-KLETAAMAKKHALERFEQEAVAVDSNLR 322
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEiRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
PRK12704 PRK12704
phosphodiesterase; Provisional
 169-314 5.02e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 5.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 169 EAKVLELTTLNKALVE----ELEVLKQRCAHEAsqaqarEEELLGLQNQqacdHAKETEELRSQLQSIKQQHQQATEQMG 244
Cdd:PRK12704  30 EAKIKEAEEEAKRILEeakkEAEAIKKEALLEA------KEEIHKLRNE----FEKELRERRNELQKLEKRLLQKEENLD 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 226437669 245 KEQEANLNLNQELQARLQTVLREKEELLQLSMErgkvLQNKQAEIRQLEEKLE--TAAMAKKHALERFEQEA 314
Cdd:PRK12704 100 RKLELLEKREEELEKKEKELEQKQQELEKKEEE----LEELIEEQLQELERISglTAEEAKEILLEKVEEEA 167
PRK11281 PRK11281
mechanosensitive channel MscK;
136-365 5.21e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  136 KDAHKSENVKLKEE----NARLRQENNSLfsQALKDQEAKVLElTTLNKALVEELEvlkQRCAhEASQAQAREEELLGLQ 211
Cdd:PRK11281   75 IDRQKEETEQLKQQlaqaPAKLRQAQAEL--EALKDDNDEETR-ETLSTLSLRQLE---SRLA-QTLDQLQNAQNDLAEY 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  212 NQQACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNLNQELQARLQT---VLREKEELLQLSMERGKVLQN---- 284
Cdd:PRK11281  148 NSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAeqaLLNAQNDLQRKSLEGNTQLQDllqk 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  285 ----KQAEIRQLEEKLETAamakkhalerfeQEAVAvdsnlrvrelQRRVDGIQKAYDELRLQSEAFKKHSLDLLSKERE 360
Cdd:PRK11281  228 qrdyLTARIQRLEHQLQLL------------QEAIN----------SKRLTLSEKTVQEAQSQDEAARIQANPLVAQELE 285


                  ....*
gi 226437669  361 LNAKL 365
Cdd:PRK11281  286 INLQL 290
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 113-183 5.52e-04

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 41.74  E-value: 5.52e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 226437669 113 EHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLFSQALkdQEAKVLELTTLNKALV 183
Cdd:PRK03992   1 ERLEALEERNSELEEQIRQLELKLRDLEAENEKLERELERLKSELEKLKSPPL--IVATVLEVLDDGRVVV 69
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 148-368 6.09e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 148 EENARLRQENNSLfSQALKDQEAKVLELTTLNKALVEELEVLKQRCAHEASQAQAREEELLGLQNQQAcDHAKETEELRS 227
Cdd:COG4942   20 DAAAEAEAELEQL-QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 228 QLQSIKQQHQQ---ATEQMGKEQEANLNLNQELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKK 304
Cdd:COG4942   98 ELEAQKEELAEllrALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 226437669 305 HALERFEQEAvavdsnlrvRELQRRVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNAKLRHL 368
Cdd:COG4942  178 ALLAELEEER---------AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 166-261 2.80e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 39.93  E-value: 2.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  166 KDQEAKVLELTTLNKALVEELEVLKQRCAHEASQAQAREEELLGLqNQQACDHAKETEELRSQLQSIKQQHQQATEQ--- 242
Cdd:PRK11448  138 EDPENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVAL-EGLAAELEEKQQELEAQLEQLQEKAAETSQErkq 216

                          90       100
                  ....*....|....*....|...
gi 226437669  243 ----MGKEQEANLNLNQELQARL 261
Cdd:PRK11448  217 krkeITDQAAKRLELSEEETRIL 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
179-350 4.08e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  179 NKALVEELEVLKQRCAHEASQAQAREEELLGLQNQ-----QACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEANLNL 253
Cdd:COG4913   608 NRAKLAALEAELAELEEELAEAEERLEALEAELDAlqerrEALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDL 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  254 NQ------ELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMAKKHAL-----ERFEQEAVAVDSNLR 322
Cdd:COG4913   688 AAleeqleELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleERFAAALGDAVEREL 767

                         170       180       190
                  ....*....|....*....|....*....|..
gi 226437669  323 VRELQRRVDG----IQKAYDELRLQSEAFKKH 350
Cdd:COG4913   768 RENLEERIDAlrarLNRAEEELERAMRAFNRE 799
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
100-273 5.92e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.74  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  100 KRLQEMEKL--KAQSEHIQKLENHFMILASNHEQMIRFKDAHKSENVKLKEENARLRQENNSLfSQALKDQEAKVLELT- 176
Cdd:COG4913   252 ELLEPIRELaeRYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL-EARLDALREELDELEa 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669  177 TLNKALVEELEVLKQRCAHEASQAQAREEELLGLQNQ------QACDHAKETEELRSQLQSIKQQHQQATEQMGKEQEAN 250
Cdd:COG4913   331 QIRGNGGDRLEQLEREIERLERELEERERRRARLEALlaalglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                         170       180
                  ....*....|....*....|...
gi 226437669  251 LNLNQELQARLQTVLREKEELLQ 273
Cdd:COG4913   411 EAALRDLRRELRELEAEIASLER 433
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
151-340 7.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 38.46  E-value: 7.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 151 ARLRQENNSLFSQALKDQEAKvlELTTLNKALVEeleVLKQRCAHEASQAQAREEELLGLQNQQACDHAKETEELRSQLQ 230
Cdd:COG3206  199 EEFRQKNGLVDLSEEAKLLLQ--QLSELESQLAE---ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLA 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437669 231 SIKQQHQQATEQMGKEQEANLNLNQELQARLQTVLREKEELLQLSMERGKVLQNKQAEIRQLEEKLETAAMakkhALERF 310
Cdd:COG3206  274 ELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA----ELPEL 349

                        170       180       190
                 ....*....|....*....|....*....|
gi 226437669 311 EQEAvavdsnlrvRELQRRVDGIQKAYDEL 340
Cdd:COG3206  350 EAEL---------RRLEREVEVARELYESL 370
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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