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Conserved domains on  [gi|9627533|ref|NP_042056|]
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secreted complement-binding protein [Variola virus]

Protein Classification

PHA02927 family protein( domain architecture ID 11476114)

PHA02927 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1-263 0e+00

secreted complement-binding protein; Provisional


:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 520.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     1 MKVERVTFLTLLGIGCVLSCCTIPSRPINMTFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80
Cdd:PHA02927   1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    81 CIKRRCPSPRDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHN 160
Cdd:PHA02927  81 CIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRHN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   161 GYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSNPPTCQIVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKL 240
Cdd:PHA02927 161 GYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKL 240

                        250       260
                 ....*....|....*....|...
gi 9627533   241 SGSSSSTCSPGNTWQPELPKCVR 263
Cdd:PHA02927 241 SGSSSSTCSPGNTWQPELPKCVR 263
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1-263 0e+00

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 520.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     1 MKVERVTFLTLLGIGCVLSCCTIPSRPINMTFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80
Cdd:PHA02927   1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    81 CIKRRCPSPRDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHN 160
Cdd:PHA02927  81 CIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRHN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   161 GYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSNPPTCQIVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKL 240
Cdd:PHA02927 161 GYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKL 240

                        250       260
                 ....*....|....*....|...
gi 9627533   241 SGSSSSTCSPGNTWQPELPKCVR 263
Cdd:PHA02927 241 SGSSSSTCSPGNTWQPELPKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 148-202 1.30e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 1.30e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533  148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSN-PPTCQ 202
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 148-201 6.92e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 6.92e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 9627533     148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSNP-PTC 201
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
148-201 6.11e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 6.11e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 9627533    148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-GEWSNP-PTC 201
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1-263 0e+00

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 520.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     1 MKVERVTFLTLLGIGCVLSCCTIPSRPINMTFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80
Cdd:PHA02927   1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYAKCTGTGWTLFNQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    81 CIKRRCPSPRDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTGSMVWNPKAPICESVKCQLPPSISNGRHN 160
Cdd:PHA02927  81 CIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRHN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   161 GYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSNPPTCQIVKCPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKL 240
Cdd:PHA02927 161 GYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKL 240

                        250       260
                 ....*....|....*....|...
gi 9627533   241 SGSSSSTCSPGNTWQPELPKCVR 263
Cdd:PHA02927 241 SGSSSSTCSPGNTWQPELPKCVR 263
PHA02639 PHA02639
EEV host range protein; Provisional
 86-263 4.06e-26

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 103.59  E-value: 4.06e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    86 CPSPRDIDNGHLD--IGGVDFGSSITYSCNSGYYLIGEYKSYCkLGSTGSMVWNPKAPICESVKCQLPPSISNGRHNGYN 163
Cdd:PHA02639  22 CDKPDDISNGFITelMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKR 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   164 DFYTDGSVVTYSCNS----GYSLIGNSGVLCSGGE-WS-NPPTCQIVKCPHPTILNGYLSS-GFKRSYSYNDNVDFTCKY 236
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKsWKpDPPICKMINCRFPALQNGYINGiPSNKKFYYKTRVGFSCKS 180

                        170       180
                 ....*....|....*....|....*..
gi 9627533   237 GYKLSGSSSSTCSPGNTWQPELPKCVR 263
Cdd:PHA02639 181 GFDLVGEKYSTCNINATWFPSIPTCVR 207
PHA02831 PHA02831
EEV host range protein; Provisional
 108-263 3.98e-19

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 84.27  E-value: 3.98e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   108 ITYSCNSGYyliGEYKSYCKLGStgsmvWNPKAPICESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSG----YSLI 183
Cdd:PHA02831  46 LEYKCNNNF---DKVFVTCNNGS-----WSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNklekYSIV 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   184 GNSGVLCSGGEW-SNPPTCQIVKCPHPTILNGYLSSgFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
Cdd:PHA02831 118 GNETVKCINKQWvPKYPVCKLIRCKYPALQNGFLNV-FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196


                 .
gi 9627533   263 R 263
Cdd:PHA02831 197 K 197
PHA02817 PHA02817
EEV Host range protein; Provisional
 143-263 2.35e-15

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 73.05  E-value: 2.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   143 CESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSG-----YSLIGNSGVLCS-GGEWS-NPPTCQIVKCPHPTILNGY 215
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNkEFPVCKIIRCRFPALQNGF 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 9627533   216 LSS-GFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCVR 263
Cdd:PHA02817  99 VNGiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSR 147
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 1-263 3.32e-15

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 73.97  E-value: 3.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     1 MKVERVTFLTLLGIGCVLSCCTIPsrpinmTFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGpiyAKCTGTGWTLFNQ 80
Cdd:PHA02954   1 MKTISVVTLLCVLPAVVYSTCTVP------TMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPN---AVCETDKWKYENP 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    81 CiKRRCpSPRDIDNGHLDIGGVDFGSSITYSCNsgyyliGEYKSYCKLGSTGSMVWNPKApICESVKCQlPPSISNGRHN 160
Cdd:PHA02954  72 C-KKMC-TVSDYVSELYDKPLYEVNSTITLICK------DETKYFRCEEKNGNTSWNDTV-TCPNAECQ-PLQLEHGSCQ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   161 GYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSNPPTCQiVKCPHPTILNGYLSSGfkrSYSYNDNVDFTCKYGYKL 240
Cdd:PHA02954 142 PVKEKYSFGEHITINCDVGYEVIGASYISCTANSWNVIPSCQ-QKCDIPSLSNGLISGS---TFSIGGVIHLSCKSGFTL 217

                        250       260
                 ....*....|....*....|...
gi 9627533   241 SGSSSSTCSPGNtWQPELPKCVR 263
Cdd:PHA02954 218 TGSPSSTCIDGK-WNPVLPICVR 239
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 148-202 1.30e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 1.30e-11
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533  148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSN-PPTCQ 202
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 148-201 6.92e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 6.92e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 9627533     148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC-SGGEWSNP-PTC 201
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 86-144 2.61e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 2.61e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 9627533   86 CPSPRDIDNGHLDIGGVDF--GSSITYSCNSGYYLIGEYKSYCklgsTGSMVWNPKAPICE 144
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 86-143 1.45e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 1.45e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533      86 CPSPRDIDNGHLDIGGVDF--GSSITYSCNSGYYLIGEYKSYCklgsTGSMVWNPKAPIC 143
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsyGDTVTYSCDPGYTLIGSSTITC----LENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
148-201 6.11e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 6.11e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 9627533    148 CQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLCSG-GEWSNP-PTC 201
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 77-190 8.16e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.78  E-value: 8.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    77 LFNQCIKRRCPSPRDIDNGHLDIGGVDF--GSSITYSCNSG-----YYLIGEYKSYCKLGSTgsmvWNPKAPICESVKCQ 149
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIYNKKTEYniGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK----WNKEFPVCKIIRCR 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 9627533   150 LpPSISNGRHNGYND---FYTDgSVVTYSCNSGYSLIGNSGVLC 190
Cdd:PHA02817  91 F-PALQNGFVNGIPDskkFYYE-SEVSFSCKPGFVLIGTKYSVC 132
PHA02639 PHA02639
EEV host range protein; Provisional
 144-261 8.32e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 49.28  E-value: 8.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533   144 ESVKCQLPPSISNGRHNGYNDFYTDGSVVTYSCNSGYSLIGNSGVLC----SGGEWSN-PPTCQIVKCPH-PTILNGYLS 217
Cdd:PHA02639  18 KSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCikdkNNAIWSNkAPFCMLKECNDpPSIINGKIY 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 9627533   218 SGfKRSYSYNDNVDFTCK----YGYKLSGSSSSTCSPGNTWQPELPKC 261
Cdd:PHA02639  98 NK-REMYKVGDEIYYVCNehkgVQYSLVGNEKITCIQDKSWKPDPPIC 144
Sushi pfam00084
Sushi repeat (SCR repeat);
86-143 1.13e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 1.13e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     86 CPSPRDIDNGHLDIGGVDF--GSSITYSCNSGYYLIGEYKSYCKLGSTgsmvWNPKAPIC 143
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYnyGASVSYECDPGYRLVGSPTITCQEDGT----WSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
21-79 5.44e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.18  E-value: 5.44e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533     21 CTIPSRPinmtFKNSVETDANaNYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WTLFN 79
Cdd:pfam00084   1 CPPPPDI----PNGKVSATKN-EYNYGASVSYECDPGYRLV--GSPTITCQEDGtWSPPF 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 206-262 9.27e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 9.27e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533  206 CPHPTILNGYLSSGFKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 17-143 2.01e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 41.46  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    17 VLSCCTIPSRPINMTFKNSVETDANANYNIGDTIEYLC---LPGYRKQKMGPIYAKCTGTG--WTLFNQCIKRRCPSP-- 89
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCgnnTRGVRYTLVGEKNIICEKDGkwNKEFPVCKIIRCRFPal 94

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 9627533    90 -RDIDNGHLDIGGVDFGSSITYSCNSGYYLIGEYKSYCKLGSTgsmvWNPKAPIC 143
Cdd:PHA02817  95 qNGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPIC 145
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 206-261 2.28e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.28  E-value: 2.28e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533     206 CPHP-TILNGYLSSGfKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
Cdd:smart00032   1 CPPPpDIENGTVTSS-SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 21-76 1.27e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.29  E-value: 1.27e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533   21 CTIPSRPINMTFKNSVEtdanaNYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WT 76
Cdd:cd00033   1 CPPPPVPENGTVTGSKG-----SYSYGSTVTYSCNEGYTLV--GSSTITCTENGgWS 50
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 21-76 6.09e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 34.42  E-value: 6.09e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533      21 CTIPSRPINMTFKNSvetdaNANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WT 76
Cdd:smart00032   1 CPPPPDIENGTVTSS-----SGTYSYGDTVTYSCDPGYTLI--GSSTITCLENGtWS 50
Sushi pfam00084
Sushi repeat (SCR repeat);
206-261 9.58e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 33.63  E-value: 9.58e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 9627533    206 CPHPTIL-NGYLSSGfKRSYSYNDNVDFTCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
Cdd:pfam00084   1 CPPPPDIpNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 21-143 9.79e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 36.51  E-value: 9.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9627533    21 CTIPSRPINMTFKNSVEtdanaNYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGWTLFNQ-CIKRRCPSPRdIDNGHL 97
Cdd:PHA02831  78 CKDPVTILNGYIKNKKD-----QYSFGDSVTYACKVNKleKYSIVGNETVKCINKQWVPKYPvCKLIRCKYPA-LQNGFL 151

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 9627533    98 DIGGVDF--GSSITYSCNSGYYLIGEYKSYCKLGStgsmVWNPKAPIC 143
Cdd:PHA02831 152 NVFEKKFyyGDIVNFKCKKGFILLGSSVSTCDINS----IWYPGIPKC 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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