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Concise Results
Standard Results
Full Results
glutathione hydrolase 1 proenzyme precursor [Homo sapiens]
Protein Classification
gamma-glutamyltransferase family protein ( domain architecture ID 10470232 )
gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond
List of domain hits
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
55-564
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 663.14
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 55 R D A LR D GG S AVDAA I AA L LC V G LMNA HS M GIGGG L F LT IY NST T R K AE VI N ARE V AP RL A FAT MF NS --- S EQ S QK GGL S 131
Cdd:pfam01019 1 L D I LR K GG N AVDAA V AA A LC L G VVEP HS S GIGGG G F ML IY DAK T G K VL VI D ARE T AP AA A TKD MF DG kgd S KL S LT GGL A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 132 V A VPGE IR G YEL AH Q R H GRLPWA R L FQ P S I Q LAR Q GFPV GKG LA A AL ENKRTVIEQQ P V L CEV F CRDRK VL RE GE R L TL P 211
Cdd:pfam01019 81 V G VPGE VA G LAE AH K R Y GRLPWA D L LE P A I K LAR D GFPV SPA LA R AL ARAEERLRAD P G L RKI F LPTGR VL KA GE L L KQ P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 212 Q LA D T Y E TL A I EG AQ AFY N G S L TA Q I V K D I QA A GGI V TAEDL N NYR AE l I EH PL NISL G DVVL Y M P SAPLS G PV L AL ILN 291
Cdd:pfam01019 161 A LA K T L E LI A E EG PD AFY R G E L AQ Q L V A D L QA N GGI I TAEDL A NYR VK - I RE PL SADY G GYTV Y S P PPSSG G IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 292 IL K G YNF S r ESVE S P E qkgl TY H RIV EA FRF AYA K RT L - LGDP K FV D V te V V R N MT S EFF A AQLRAQ I SDDTTH P I SY Y k 370
Cdd:pfam01019 240 IL E G FDL S - SLLN S A E ---- YL H LLI EA MKL AYA D RT R y LGDP D FV P V -- P V E N LL S PEY A KERAKL I NPNAAF P S SY A - 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 371 pefyt P D DGGT A H L SVV AE DG S AVS A TSTINL Y FGS K V RS P VS GIL F NNEMDDFS S P SI t N E FG VP PSPAN F I Q PGK Q PL 450
Cdd:pfam01019 312 ----- P E DGGT T H F SVV DR DG N AVS F TSTINL G FGS G V VV P GT GIL L NNEMDDFS T P PG - N A FG LD PSPAN A I A PGK R PL 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 451 SSM C PTI m V GQ DG QVRM VVGA A GG TQ I TT A TALA I IYN L WF G Y D VKR AV EE PR L H N Q l LP N V TT VE RNIDQA V T A A LE T R 530
Cdd:pfam01019 386 SSM A PTI - V LD DG KPVL VVGA P GG SR I IS A VLQV I VNV L DL G L D LQQ AV DA PR I H H Q - LP D V LE VE PGFPEE V L A E LE A R 463
490 500 510
....*....|....*....|....*....|....*.
gi 73915092 531 H H HTQIASTFIA V VQAIV -- RT A G GWA AASD S R KG G 564
Cdd:pfam01019 464 G H KVKVVEDSSS V GAIQI vr RT G G VLY AASD P R RD G 499
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
55-564
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 663.14
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 55 R D A LR D GG S AVDAA I AA L LC V G LMNA HS M GIGGG L F LT IY NST T R K AE VI N ARE V AP RL A FAT MF NS --- S EQ S QK GGL S 131
Cdd:pfam01019 1 L D I LR K GG N AVDAA V AA A LC L G VVEP HS S GIGGG G F ML IY DAK T G K VL VI D ARE T AP AA A TKD MF DG kgd S KL S LT GGL A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 132 V A VPGE IR G YEL AH Q R H GRLPWA R L FQ P S I Q LAR Q GFPV GKG LA A AL ENKRTVIEQQ P V L CEV F CRDRK VL RE GE R L TL P 211
Cdd:pfam01019 81 V G VPGE VA G LAE AH K R Y GRLPWA D L LE P A I K LAR D GFPV SPA LA R AL ARAEERLRAD P G L RKI F LPTGR VL KA GE L L KQ P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 212 Q LA D T Y E TL A I EG AQ AFY N G S L TA Q I V K D I QA A GGI V TAEDL N NYR AE l I EH PL NISL G DVVL Y M P SAPLS G PV L AL ILN 291
Cdd:pfam01019 161 A LA K T L E LI A E EG PD AFY R G E L AQ Q L V A D L QA N GGI I TAEDL A NYR VK - I RE PL SADY G GYTV Y S P PPSSG G IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 292 IL K G YNF S r ESVE S P E qkgl TY H RIV EA FRF AYA K RT L - LGDP K FV D V te V V R N MT S EFF A AQLRAQ I SDDTTH P I SY Y k 370
Cdd:pfam01019 240 IL E G FDL S - SLLN S A E ---- YL H LLI EA MKL AYA D RT R y LGDP D FV P V -- P V E N LL S PEY A KERAKL I NPNAAF P S SY A - 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 371 pefyt P D DGGT A H L SVV AE DG S AVS A TSTINL Y FGS K V RS P VS GIL F NNEMDDFS S P SI t N E FG VP PSPAN F I Q PGK Q PL 450
Cdd:pfam01019 312 ----- P E DGGT T H F SVV DR DG N AVS F TSTINL G FGS G V VV P GT GIL L NNEMDDFS T P PG - N A FG LD PSPAN A I A PGK R PL 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 451 SSM C PTI m V GQ DG QVRM VVGA A GG TQ I TT A TALA I IYN L WF G Y D VKR AV EE PR L H N Q l LP N V TT VE RNIDQA V T A A LE T R 530
Cdd:pfam01019 386 SSM A PTI - V LD DG KPVL VVGA P GG SR I IS A VLQV I VNV L DL G L D LQQ AV DA PR I H H Q - LP D V LE VE PGFPEE V L A E LE A R 463
490 500 510
....*....|....*....|....*....|....*.
gi 73915092 531 H H HTQIASTFIA V VQAIV -- RT A G GWA AASD S R KG G 564
Cdd:pfam01019 464 G H KVKVVEDSSS V GAIQI vr RT G G VLY AASD P R RD G 499
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
51-562
1.13e-169
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 490.72
E-value: 1.13e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 51 S KI G RDA LR D GG S AVDAA I AA LLCVGLMNA HS M GIGGG L F LT IY NSTTR K AEVINA R EV AP RL A FAT M FNS -- S E QSQK G 128
Cdd:COG0405 10 S QA G LEI LR A GG N AVDAA V AA AAALAVVEP HS S GIGGG G F AL IY DAKDG K VTALDG R GT AP AA A TPD M YLD ag D E IPVR G 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 129 G L S V A VPG EIR G Y E L AH Q R H G R LP W A R L FQ P S I Q LA RQ GFPV GKG LAA A L ENKRTVIEQQ P VLCEV F CR D RKVLRE G ER L 208
Cdd:COG0405 90 P L A V G VPG TVA G W E A AH E R Y G T LP L A E L LA P A I R LA ED GFPV SPR LAA L L AAAAERLARD P GAAAI F LP D GRPPKA G DI L 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 209 TL P Q LA D T YETL A I EGA Q AFY N G SLTAQ IV KDI QAAGG IV T A EDL NN YRAE LI E h PL NISLGDVVL Y - MP s A P LS G PV L A 287
Cdd:COG0405 170 RQ P D LA A T LRRI A E EGA D AFY R G EIAEA IV AAV QAAGG LL T L EDL AA YRAE WR E - PL SGTYRGYTV Y s MP - P P SQ G IA L L 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 288 L ILNIL K G YNFSRESVE S P E qkgl TY H RIV EA FRF A Y A K R - TL LGDP K FVDV T ev V RNMT S EFF AA QLR A Q I SD D TTH P i 366
Cdd:COG0405 248 Q ILNIL E G FDLAALGPD S A E ---- YV H LLA EA MKL A F A D R d RY LGDP D FVDV P -- V EGLL S PAY AA ERA A L I DP D RAT P - 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 367 S YYKPEFYT P DD G G T A HLSVV AE DG S AVS A T ST I NLY FGS K V RS P VS G I L F NN EM DDFS S psitnefgv P P SPA N FIQ PG 446
Cdd:COG0405 321 S PRPGDPTG P ES G D T T HLSVV DR DG N AVS L T QS I YGG FGS G V VV P GT G F L L NN RG DDFS L --------- D P GHP N ALA PG 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 447 K Q P L S S M C PT i M V GQ DG QVRM V V G AA GG TQ I TTATALAIIYN L W FG YDVKR AV EE PR L H N Q L LP NVTTV E RNIDQ AV T AA 526
Cdd:COG0405 392 K R P R S T M S PT - I V LK DG KPVL V F G SP GG SR I PQTVLQVLLNV L D FG MNPQE AV DA PR W H H Q G LP DTLEL E PRFPP AV I AA 470
490 500 510
....*....|....*....|....*....|....*..
gi 73915092 527 L ET R H H HTQIASTFIAVV QAI V R TAG G - WAA A S D S R K 562
Cdd:COG0405 471 L RA R G H KVEVVPDWSGGA QAI L R DPD G v LEG A A D P R R 507
PLN02198
PLN02198 glutathione gamma-glutamylcysteinyltransferase
28-569
3.34e-137
glutathione gamma-glutamylcysteinyltransferase
Pssm-ID: 177849
Cd Length: 573
Bit Score: 410.62
E-value: 3.34e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 28 S A S K EPDNH V YTRA AVA A D AKQ CS K IG RDA LR D GG S A V DA AI AA L LC V G LMNAH S M GIGGG L F LT I y NSTTRKAEVINA R 107
Cdd:PLN02198 21 A A Q K RQQSI V ASHG AVA T D DGR CS V IG MNV LR E GG N A I DA SV AA A LC L G VVSPA S S GIGGG A F TL I - KLANGEEIAYDS R 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 108 E V AP RL A FAT M F - NSS E QSQ KG G LSV A VPGE IR G YEL A HQR HG R LPW A RL FQ P SIQ LA RQ GF PVG K G L AAALENK R TV I E 186
Cdd:PLN02198 100 E T AP LS A TEN M Y g GNV E LKK KG A LSV G VPGE VA G LFT A WKQ HG K LPW K RL VR P AEK LA AE GF KIS K Y L YMQMNAT R SD I L 179
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 187 QQPV L CEV F CRDRKVLRE G ERLTL P Q LA D T YETLAIE G AQ AFYNG SLTAQI V K DIQ AA GGI V T AE DL NN YR AELI E HPLN 266
Cdd:PLN02198 180 ADKG L SDL F VSNGELKKP G TICHN P K LA L T LRLIGEY G PK AFYNG TVGVNL V R DIQ KS GGI I T LK DL QS YR VKVK E PLSA 259
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 267 IS LG DV VL Y MP SAPLS G PVLA LILNIL KG Y NFS r ES V ES P eqkg L TY HR IV EA FRF A Y A K R TL LGDP K FVDVT E VV RN M T 346
Cdd:PLN02198 260 DI LG YR VL G MP PPSSG G AAMM LILNIL AQ Y GIP - SG V SG P ---- L GV HR LI EA LKH A F A V R MN LGDP D FVDVT K VV SD M L 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 347 S EF FA AQ L RAQ I S D DT T HPISY Y KPEFYTP DD G GT A HLS VVAEDGS AVS A TSTIN L YFG SKVR SP VS GI LF NNEMDDFS S 426
Cdd:PLN02198 335 S PK FA QD L KSK I N D NK T FDPKH Y GGRWNQI DD H GT S HLS IIDSERN AVS M TSTIN G YFG ALML SP ST GI VL NNEMDDFS I 414
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 427 P si TNEF G V ---- PP S PANFI Q PGK Q PLSSM C PTI MV g Q DG Q V RMV VGA A GG TQ I TTA T ALAIIYNLWFGY D VKRA V EE P 502
Cdd:PLN02198 415 P -- MKSG G N ldvp PP A PANFI R PGK R PLSSM T PTI VL - K DG K V KAA VGA S GG AN I IAG T TEVYLNHFFLKM D PLSS V LA P 491
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 503 R LHN QL L PN VTTV E R --------- N I DQ A VTAA LE TRH H HTQ - IA STF IA -- V VQ AIVRTA GG WA --- A A SD S RKGG E P A 567
Cdd:PLN02198 492 R IYH QL I PN RASY E N wttvyndhf E I PK A TRVV LE KKG H VLS p IA GGT IA qf I VQ ESGENS GG RS elv A V SD P RKGG F P S 571
..
gi 73915092 568 GY 569
Cdd:PLN02198 572 GY 573
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
43-561
4.22e-127
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 382.58
E-value: 4.22e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 43 VA ADAKQC S K IG R D A L RD GG S A V DAA I A AL L CVGLMNAHSM G I GGG L F LT I YNST T RKAEV I NA RE V AP RL A FAT MF NS - 121
Cdd:TIGR00066 3 VA SLHALA S E IG E D I L KE GG N A F DAA V A VG L ALAVVEPFMT G L GGG G F ML I SGKK T KDTTA I DF RE R AP AK A TRD MF LD k 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 122 ----- SEQ S QK GGL SVA VPG EIR G Y E L A HQRH G R LP WAR L FQ P S I Q LAR Q GFP VGKG LA AA LE NKRT V IEQQPVLC - EV F 195
Cdd:TIGR00066 83 sgnpl PGK S LT GGL AIG VPG TVA G L E A A LKKY G T LP LKD L IE P A I K LAR N GFP INEA LA DT LE LYEE V LLTTKEDS k DI F 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 196 CRDR K V L R EG ER L TLPQ LA DTY E TL A IE G AQ AFY N G SLTAQ I VKDI Q AA GGI V T AE DL NN Y RA E l I EH PL NISL - G DV V L 274
Cdd:TIGR00066 163 NPTG K P L K EG DT L VQKD LA KSL E LI A EN G PD AFY K G DIAES I IDTL Q KN GGI M T KK DL AA Y DV E - I RK PL SGDY r G YQ V Y 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 275 YM P SAPLS G PV L ALI LNIL KGYNF S RESVE S P E Q kglt Y HRIV EA FRFA YA K R T - L LGDP K FVDV T ev VRNMTSEFF A AQ 353
Cdd:TIGR00066 242 TT P PPSSG G IH L LQA LNIL ENFDL S QYGDG S A E T ---- Y QLLA EA MKLS YA D R S r Y LGDP E FVDV P -- LEELLDKRY A KE 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 354 L RAQ I SDDTTH P I S YYK P EF Y T P DD G - G T A H L SVV AE DG S AVS A T S TINL Y FGS K V RS P VS GIL F NNEMDDFS spsitne 432
Cdd:TIGR00066 316 L AQS I KINKVD P K S TIY P GA Y Q P NE G s Q T T H F SVV DR DG N AVS L T T TINL E FGS G V HA P DT GIL L NNEMDDFS ------- 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 433 fg VP P SP AN FIQ P G K Q PLSSM C PTI MV g Q DG QVRM VVG AA GG TQ I T T ATALA I IYNLWF G YDVKR AV E EPR L H N Q L LP NV 512
Cdd:TIGR00066 389 -- LK P GG AN AVE P N K R PLSSM A PTI VL - K DG KPDL VVG SP GG SR I I T TVLQT I VRHIDY G MPLAE AV S EPR I H H Q W LP DE 465
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 73915092 513 TTV E RNIDQA V TAA L ETR - H HH T QIASTFIA VVQAI VRTAG GW A - AA SD S R 561
Cdd:TIGR00066 466 LRL E KGFPDD V LQL L KDM g H KV T LKEVFPMG VVQAI RVDPE GW L y GV SD P R 516
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
55-564
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 663.14
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 55 R D A LR D GG S AVDAA I AA L LC V G LMNA HS M GIGGG L F LT IY NST T R K AE VI N ARE V AP RL A FAT MF NS --- S EQ S QK GGL S 131
Cdd:pfam01019 1 L D I LR K GG N AVDAA V AA A LC L G VVEP HS S GIGGG G F ML IY DAK T G K VL VI D ARE T AP AA A TKD MF DG kgd S KL S LT GGL A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 132 V A VPGE IR G YEL AH Q R H GRLPWA R L FQ P S I Q LAR Q GFPV GKG LA A AL ENKRTVIEQQ P V L CEV F CRDRK VL RE GE R L TL P 211
Cdd:pfam01019 81 V G VPGE VA G LAE AH K R Y GRLPWA D L LE P A I K LAR D GFPV SPA LA R AL ARAEERLRAD P G L RKI F LPTGR VL KA GE L L KQ P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 212 Q LA D T Y E TL A I EG AQ AFY N G S L TA Q I V K D I QA A GGI V TAEDL N NYR AE l I EH PL NISL G DVVL Y M P SAPLS G PV L AL ILN 291
Cdd:pfam01019 161 A LA K T L E LI A E EG PD AFY R G E L AQ Q L V A D L QA N GGI I TAEDL A NYR VK - I RE PL SADY G GYTV Y S P PPSSG G IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 292 IL K G YNF S r ESVE S P E qkgl TY H RIV EA FRF AYA K RT L - LGDP K FV D V te V V R N MT S EFF A AQLRAQ I SDDTTH P I SY Y k 370
Cdd:pfam01019 240 IL E G FDL S - SLLN S A E ---- YL H LLI EA MKL AYA D RT R y LGDP D FV P V -- P V E N LL S PEY A KERAKL I NPNAAF P S SY A - 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 371 pefyt P D DGGT A H L SVV AE DG S AVS A TSTINL Y FGS K V RS P VS GIL F NNEMDDFS S P SI t N E FG VP PSPAN F I Q PGK Q PL 450
Cdd:pfam01019 312 ----- P E DGGT T H F SVV DR DG N AVS F TSTINL G FGS G V VV P GT GIL L NNEMDDFS T P PG - N A FG LD PSPAN A I A PGK R PL 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 451 SSM C PTI m V GQ DG QVRM VVGA A GG TQ I TT A TALA I IYN L WF G Y D VKR AV EE PR L H N Q l LP N V TT VE RNIDQA V T A A LE T R 530
Cdd:pfam01019 386 SSM A PTI - V LD DG KPVL VVGA P GG SR I IS A VLQV I VNV L DL G L D LQQ AV DA PR I H H Q - LP D V LE VE PGFPEE V L A E LE A R 463
490 500 510
....*....|....*....|....*....|....*.
gi 73915092 531 H H HTQIASTFIA V VQAIV -- RT A G GWA AASD S R KG G 564
Cdd:pfam01019 464 G H KVKVVEDSSS V GAIQI vr RT G G VLY AASD P R RD G 499
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
51-562
1.13e-169
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 490.72
E-value: 1.13e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 51 S KI G RDA LR D GG S AVDAA I AA LLCVGLMNA HS M GIGGG L F LT IY NSTTR K AEVINA R EV AP RL A FAT M FNS -- S E QSQK G 128
Cdd:COG0405 10 S QA G LEI LR A GG N AVDAA V AA AAALAVVEP HS S GIGGG G F AL IY DAKDG K VTALDG R GT AP AA A TPD M YLD ag D E IPVR G 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 129 G L S V A VPG EIR G Y E L AH Q R H G R LP W A R L FQ P S I Q LA RQ GFPV GKG LAA A L ENKRTVIEQQ P VLCEV F CR D RKVLRE G ER L 208
Cdd:COG0405 90 P L A V G VPG TVA G W E A AH E R Y G T LP L A E L LA P A I R LA ED GFPV SPR LAA L L AAAAERLARD P GAAAI F LP D GRPPKA G DI L 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 209 TL P Q LA D T YETL A I EGA Q AFY N G SLTAQ IV KDI QAAGG IV T A EDL NN YRAE LI E h PL NISLGDVVL Y - MP s A P LS G PV L A 287
Cdd:COG0405 170 RQ P D LA A T LRRI A E EGA D AFY R G EIAEA IV AAV QAAGG LL T L EDL AA YRAE WR E - PL SGTYRGYTV Y s MP - P P SQ G IA L L 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 288 L ILNIL K G YNFSRESVE S P E qkgl TY H RIV EA FRF A Y A K R - TL LGDP K FVDV T ev V RNMT S EFF AA QLR A Q I SD D TTH P i 366
Cdd:COG0405 248 Q ILNIL E G FDLAALGPD S A E ---- YV H LLA EA MKL A F A D R d RY LGDP D FVDV P -- V EGLL S PAY AA ERA A L I DP D RAT P - 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 367 S YYKPEFYT P DD G G T A HLSVV AE DG S AVS A T ST I NLY FGS K V RS P VS G I L F NN EM DDFS S psitnefgv P P SPA N FIQ PG 446
Cdd:COG0405 321 S PRPGDPTG P ES G D T T HLSVV DR DG N AVS L T QS I YGG FGS G V VV P GT G F L L NN RG DDFS L --------- D P GHP N ALA PG 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 447 K Q P L S S M C PT i M V GQ DG QVRM V V G AA GG TQ I TTATALAIIYN L W FG YDVKR AV EE PR L H N Q L LP NVTTV E RNIDQ AV T AA 526
Cdd:COG0405 392 K R P R S T M S PT - I V LK DG KPVL V F G SP GG SR I PQTVLQVLLNV L D FG MNPQE AV DA PR W H H Q G LP DTLEL E PRFPP AV I AA 470
490 500 510
....*....|....*....|....*....|....*..
gi 73915092 527 L ET R H H HTQIASTFIAVV QAI V R TAG G - WAA A S D S R K 562
Cdd:COG0405 471 L RA R G H KVEVVPDWSGGA QAI L R DPD G v LEG A A D P R R 507
PLN02198
PLN02198 glutathione gamma-glutamylcysteinyltransferase
28-569
3.34e-137
glutathione gamma-glutamylcysteinyltransferase
Pssm-ID: 177849
Cd Length: 573
Bit Score: 410.62
E-value: 3.34e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 28 S A S K EPDNH V YTRA AVA A D AKQ CS K IG RDA LR D GG S A V DA AI AA L LC V G LMNAH S M GIGGG L F LT I y NSTTRKAEVINA R 107
Cdd:PLN02198 21 A A Q K RQQSI V ASHG AVA T D DGR CS V IG MNV LR E GG N A I DA SV AA A LC L G VVSPA S S GIGGG A F TL I - KLANGEEIAYDS R 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 108 E V AP RL A FAT M F - NSS E QSQ KG G LSV A VPGE IR G YEL A HQR HG R LPW A RL FQ P SIQ LA RQ GF PVG K G L AAALENK R TV I E 186
Cdd:PLN02198 100 E T AP LS A TEN M Y g GNV E LKK KG A LSV G VPGE VA G LFT A WKQ HG K LPW K RL VR P AEK LA AE GF KIS K Y L YMQMNAT R SD I L 179
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 187 QQPV L CEV F CRDRKVLRE G ERLTL P Q LA D T YETLAIE G AQ AFYNG SLTAQI V K DIQ AA GGI V T AE DL NN YR AELI E HPLN 266
Cdd:PLN02198 180 ADKG L SDL F VSNGELKKP G TICHN P K LA L T LRLIGEY G PK AFYNG TVGVNL V R DIQ KS GGI I T LK DL QS YR VKVK E PLSA 259
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 267 IS LG DV VL Y MP SAPLS G PVLA LILNIL KG Y NFS r ES V ES P eqkg L TY HR IV EA FRF A Y A K R TL LGDP K FVDVT E VV RN M T 346
Cdd:PLN02198 260 DI LG YR VL G MP PPSSG G AAMM LILNIL AQ Y GIP - SG V SG P ---- L GV HR LI EA LKH A F A V R MN LGDP D FVDVT K VV SD M L 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 347 S EF FA AQ L RAQ I S D DT T HPISY Y KPEFYTP DD G GT A HLS VVAEDGS AVS A TSTIN L YFG SKVR SP VS GI LF NNEMDDFS S 426
Cdd:PLN02198 335 S PK FA QD L KSK I N D NK T FDPKH Y GGRWNQI DD H GT S HLS IIDSERN AVS M TSTIN G YFG ALML SP ST GI VL NNEMDDFS I 414
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 427 P si TNEF G V ---- PP S PANFI Q PGK Q PLSSM C PTI MV g Q DG Q V RMV VGA A GG TQ I TTA T ALAIIYNLWFGY D VKRA V EE P 502
Cdd:PLN02198 415 P -- MKSG G N ldvp PP A PANFI R PGK R PLSSM T PTI VL - K DG K V KAA VGA S GG AN I IAG T TEVYLNHFFLKM D PLSS V LA P 491
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 503 R LHN QL L PN VTTV E R --------- N I DQ A VTAA LE TRH H HTQ - IA STF IA -- V VQ AIVRTA GG WA --- A A SD S RKGG E P A 567
Cdd:PLN02198 492 R IYH QL I PN RASY E N wttvyndhf E I PK A TRVV LE KKG H VLS p IA GGT IA qf I VQ ESGENS GG RS elv A V SD P RKGG F P S 571
..
gi 73915092 568 GY 569
Cdd:PLN02198 572 GY 573
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
43-561
4.22e-127
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 382.58
E-value: 4.22e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 43 VA ADAKQC S K IG R D A L RD GG S A V DAA I A AL L CVGLMNAHSM G I GGG L F LT I YNST T RKAEV I NA RE V AP RL A FAT MF NS - 121
Cdd:TIGR00066 3 VA SLHALA S E IG E D I L KE GG N A F DAA V A VG L ALAVVEPFMT G L GGG G F ML I SGKK T KDTTA I DF RE R AP AK A TRD MF LD k 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 122 ----- SEQ S QK GGL SVA VPG EIR G Y E L A HQRH G R LP WAR L FQ P S I Q LAR Q GFP VGKG LA AA LE NKRT V IEQQPVLC - EV F 195
Cdd:TIGR00066 83 sgnpl PGK S LT GGL AIG VPG TVA G L E A A LKKY G T LP LKD L IE P A I K LAR N GFP INEA LA DT LE LYEE V LLTTKEDS k DI F 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 196 CRDR K V L R EG ER L TLPQ LA DTY E TL A IE G AQ AFY N G SLTAQ I VKDI Q AA GGI V T AE DL NN Y RA E l I EH PL NISL - G DV V L 274
Cdd:TIGR00066 163 NPTG K P L K EG DT L VQKD LA KSL E LI A EN G PD AFY K G DIAES I IDTL Q KN GGI M T KK DL AA Y DV E - I RK PL SGDY r G YQ V Y 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 275 YM P SAPLS G PV L ALI LNIL KGYNF S RESVE S P E Q kglt Y HRIV EA FRFA YA K R T - L LGDP K FVDV T ev VRNMTSEFF A AQ 353
Cdd:TIGR00066 242 TT P PPSSG G IH L LQA LNIL ENFDL S QYGDG S A E T ---- Y QLLA EA MKLS YA D R S r Y LGDP E FVDV P -- LEELLDKRY A KE 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 354 L RAQ I SDDTTH P I S YYK P EF Y T P DD G - G T A H L SVV AE DG S AVS A T S TINL Y FGS K V RS P VS GIL F NNEMDDFS spsitne 432
Cdd:TIGR00066 316 L AQS I KINKVD P K S TIY P GA Y Q P NE G s Q T T H F SVV DR DG N AVS L T T TINL E FGS G V HA P DT GIL L NNEMDDFS ------- 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 433 fg VP P SP AN FIQ P G K Q PLSSM C PTI MV g Q DG QVRM VVG AA GG TQ I T T ATALA I IYNLWF G YDVKR AV E EPR L H N Q L LP NV 512
Cdd:TIGR00066 389 -- LK P GG AN AVE P N K R PLSSM A PTI VL - K DG KPDL VVG SP GG SR I I T TVLQT I VRHIDY G MPLAE AV S EPR I H H Q W LP DE 465
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 73915092 513 TTV E RNIDQA V TAA L ETR - H HH T QIASTFIA VVQAI VRTAG GW A - AA SD S R 561
Cdd:TIGR00066 466 LRL E KGFPDD V LQL L KDM g H KV T LKEVFPMG VVQAI RVDPE GW L y GV SD P R 516
PLN02180
PLN02180 gamma-glutamyl transpeptidase 4
43-568
1.15e-112
gamma-glutamyl transpeptidase 4
Pssm-ID: 177836
Cd Length: 639
Bit Score: 349.36
E-value: 1.15e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 43 VAAD AKQ CS K IG RDA LR D GG S AVDAA I A AL LC V G LM N AH S M GIGGG L FL TIYNSTTR KAE VINA RE V AP RL A FAT M F - N S 121
Cdd:PLN02180 85 VAAD DAR CS E IG ASV LR R GG H AVDAA V A IT LC I G VV N PM S S GIGGG S FL IVSSQKDS KAE AFDM RE T AP LA A SKD M Y k N D 164
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 122 SEQSQK G G LS VA VPGEI R G YEL A HQ R H GRLPW AR LF Q P S I Q LAR Q GF P V GKG L AA A LENKRTV I EQQ P V L CE VF C R DRK V 201
Cdd:PLN02180 165 ASAKSL G A LS MG VPGEI A G LYE A WK R Y GRLPW KP LF E P A I E LAR D GF V V HPY L GK A ISSHAAM I LKD P G L RS VF S R NGQ V 244
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 202 L RE GE RLTL P Q LA DTY ET LAIE G AQ AFYNG SLTAQI VKD IQA AGGI V T AE DL NN Y RAELIEHPLNISL G DVVLY MP sa P L 281
Cdd:PLN02180 245 L KP GE TCYN P E LA QSL ET ISEQ G PG AFYNG TIGEKL VKD VKK AGGI I T MD DL RS Y EVLVTDAMSVDVM G YTIHG MP -- P P 322
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 282 SG PV L -- ALILN IL KG Y N fsre SVESPEQKG L TY HR IV EA FRFAY A K R TL LGDP K FV DV T EVVRN M T S EFF A AQLRAQ I S 359
Cdd:PLN02180 323 SG GT L gf SMVID IL DS Y S ---- NLYTASGRE L GL HR LI EA MKHMF A A R MD LGDP E FV NI T NAMNQ M L S KAH A EEIQKR I F 398
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 360 D D TT H P IS YY KPEFYTPD D G GT A H LSV V AE D GSA VS A TST I N LY FG SK V R SP VS GI LF NNEMDDFS S P SITNEFGV PP S P 439
Cdd:PLN02180 399 D N TT F P PE YY LNRWSQLR D Q GT S H FCI V DA D RNS VS M TST V N YG FG AG V L SP ST GI VL NNEMDDFS T P AEITPDML PP A P 478
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 440 A NFI Q P G K Q PLSSM C P t IMVGQ DG QVRMVV G A AGG TQ I TT A TALAIIYNLWFGYDV K R AVE EP R LHNQ L L PNV TTV E R -- 517
Cdd:PLN02180 479 T NFI E P N K R PLSSM T P - LVITK DG EFVAAL G G AGG MH I IP A VLQVFLNCFVLNMKP K E AVE SA R IYHR L I PNV VSY E N ft 557
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 518 ------- NIDQAVTAA L ET R H H HTQIA S TF i A V VQ A IV RT ------------------------ A G GWA A AS D S RK G G E P 566
Cdd:PLN02180 558 aingdhi GVSEDTKMF L AE R G H ELKAL S GG - A I VQ L IV QS fkeekeeemiieigrkigkkskpl K G LLT A VC D P RK D G K P 636
..
gi 73915092 567 A G 568
Cdd:PLN02180 637 A A 638
ggt
PRK09615 gamma-glutamyltranspeptidase; Reviewed
41-569
5.81e-91
gamma-glutamyltranspeptidase; Reviewed
Pssm-ID: 181992
Cd Length: 581
Bit Score: 291.04
E-value: 5.81e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 41 A A V A A D A K Q csk I G R D A L RD GG S AVDAA I A ALLCVGLMNAHSMGI GGG L F LTI y NSTTRKAEV I NA RE V AP RL A FAT MF - 119
Cdd:PRK09615 53 A S V D A T A T Q --- V G V D I L KQ GG N AVDAA V A VGYALAVTHPQAGNL GGG G F MLL - RTKNGNTTA I DF RE M AP AK A TRD MF l 128
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 120 ----- NS S EQ S QKGG L SVAV PG EIR G YE LA HQRH G RL P WARLF QP SIQ LAR Q GF P V GKG LA AA L EN - KRT V IEQQPVLCE 193
Cdd:PRK09615 129 ddqgn PD S KK S LTSH L ASGT PG TVA G FS LA LDKY G TM P LNKVV QP AFK LAR D GF I V NDA LA DD L KT y GSE V LPNHENSKA 208
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 194 V F CRDRKV L RE G ER L TLPQ LA DTY E TL A IE G AQ AFY N G SLTA QI VKDI Q AA GG IV T A EDL NN Y R A el I E H - P LNISL - G D 271
Cdd:PRK09615 209 I F WKEGEP L KK G DK L VQAN LA KSL E MI A EN G PD AFY K G TIAD QI AQEM Q KN GG LI T K EDL AA Y K A -- V E R t P ISGDY r G Y 286
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 272 V V LY MP SAPLS G PVLAL ILNIL KGYNFSRESVE S PEQKGL tyhr IV EA FRF AYA K R T - L LGDP K FV D V T ev VRNM T SEFF 350
Cdd:PRK09615 287 Q V YS MP PPSSG G IHIVQ ILNIL ENFDMKKYGFG S ADAMQI ---- MA EA EKY AYA D R S e Y LGDP D FV K V P -- WQAL T NKAY 360
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 351 A AQLRA QI SDDTTH P I S YYK P EFYT P - DDGG T A H L SVV AE DG S AV SA T S T I N LY FG SKVRSPV SGIL F NN E MDDFS S - P S 428
Cdd:PRK09615 361 A KSIAD QI DINKAK P S S EIR P GKLA P y ESNQ T T H F SVV DK DG N AV AV T Y T L N TT FG TGIVAGN SGIL L NN Q MDDFS A k P G 440
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73915092 429 IT N EF G VPPSP AN FIQ P G K Q PLSSM C PTI M V g Q DG QVRM V V G AA GG TQ I T T ATALAIIYNLWF G YD V KR A VEE PR L H N Q L 508
Cdd:PRK09615 441 VP N VY G LVGGD AN AVG P N K R PLSSM S PTI V V - K DG KTWL V T G SP GG SR I I T TVLQMVVNSIDY G MN V AE A TNA PR F H H Q W 519
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 73915092 509 LP NVTT VE RNIDQAVTAA LE TRHHHTQIASTFIAVVQAI V RTA G GWAA ASD S R KGGE - P AGY 569
Cdd:PRK09615 520 LP DELR VE KGFSPDTLKL LE AKGQKVALKEAMGSTQSIM V GPD G ELYG ASD P R SVDD l T AGY 581
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
