|
Name |
Accession |
Description |
Interval |
E-value |
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
6-565 |
7.94e-134 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 399.05 E-value: 7.94e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 6 QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDA----SEVAVE 81
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 82 YLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPapLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHS 161
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 162 SqassnveegsNNPTFELQEPSpqkevtkldngqalpvtsassegrahlsqkhlHLTQCMSLCVCYSASIGGIATLTGTA 241
Cdd:pfam00939 159 A----------FGSDPEKGSER--------------------------------RIGAYLMWTVYQSTSITSAMFLTAMA 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 242 PNLVLQGQINSlfpQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNfgigekmqeqqqAAYCVIQTEHRL 321
Cdd:pfam00939 197 PNLLLLGLMNS---ILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVP------------DAKAIAKTELKE 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 322 LGPMTFAEKAISILFVILVLLWFTRepgfflgwgnlafpnakGESMVSDGTVAIFIGIIMFIipskfpgltqdpenpgkl 401
Cdd:pfam00939 262 LGPMTFREKALLGLFVLLLLLWIFG-----------------GSLNIDATTVAIIGLALMLL------------------ 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 402 kapLGLLDWK-TVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQS--VPAPAIAIILSLLVATFTECTSNVA 478
Cdd:pfam00939 307 ---LRILDWKdIVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSgfSPAMAFIIILSLFYLSHYLFASATA 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 479 TTTIFLPILASMAQAICLHP-LYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAIN 556
Cdd:pfam00939 384 HTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGN 463
|
....*....
gi 4506979 557 SWGIPLFSL 565
Cdd:pfam00939 464 WWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-559 |
2.42e-92 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 289.10 E-value: 2.42e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 39 AYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalp 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 199 vtsassegrahlsqkhlhltQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNvvnFASWFSFAFPTMVIll 278
Cdd:cd01115 126 --------------------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQGFS---FFEFTPIGLPLLII-- 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 279 llawlwlqilflgfnfrknfgigekmqeqqqaaycviqtehrllgpmtfaekaisilfVILVLLWFTREPGFFLGWGNLA 358
Cdd:cd01115 181 ----------------------------------------------------------GLLYLWFIFRLAVLIITIVLLA 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 359 FPNA-KGESMVSDGTVAIFIGIIMFiipskfpgltqdpenpgklkaplGLLDWKTVNQKMPWNIVLLLGGGYALAKGSER 437
Cdd:cd01115 203 ALAAiTGLLPVSVAIAIGAIVLVFG-----------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALES 259
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 438 SGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLP 516
Cdd:cd01115 260 SGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLP 339
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 4506979 517 VATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWG 559
Cdd:cd01115 340 VGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-558 |
2.93e-75 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 243.91 E-value: 2.93e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 91 FGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSsqassnvEE 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGS-------EK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 171 GSNNPTFelqepspqkevtkldngqalpvtsassegrahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQI 250
Cdd:COG0471 74 RSKFGSA-------------------------------------------LLLPIAFAASIGGMGTLIGTPPNLIAAGLL 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 251 NSLFPQNgnvVNFASWFSFAFPTMVILLLLAWLwlqilFLGFNFRKNFGIGEKMQEqqqaaycVIQTEHRLLGPMTFAEK 330
Cdd:COG0471 111 EEATGIP---ISFFEWMLVGLPVALVGLLLLWL-----VLYRLLPPEIKEVPGSKE-------VIREELAELGPLSRREK 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 331 AISILFVILVLLWFTrepGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpenpgklkapLGLLDW 410
Cdd:COG0471 176 IALAIFALTVLLWIT---GSLHG--------------IPIAVVALLGAVLLLL---------------------TGVLTW 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 411 KTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILAS 489
Cdd:COG0471 218 KDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAIS 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4506979 490 MAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 558
Cdd:COG0471 298 LAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
33-558 |
6.33e-48 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 173.30 E-value: 6.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 33 SKEAYCAYAI-ILMALFWCTEALPLAVTALFP-LILFPMMGIVDASEV--AVEYLKDSNL-LFFGGLLVAIAVEHWNLHK 107
Cdd:TIGR00785 7 NSGAWLLLAIfVAAIVGWILEPLPLPVTALLAiPIIAVLLGVLSAFKFknALSGFADPTIwLFFGAFILATALVKTGLGK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 108 RIALRVLLIVGVRPAPL-ILGFMLVTAFLSMWISNTA-TSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqepspq 185
Cdd:TIGR00785 87 RIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLLGSK----------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 186 kevtkldngqalPVTSASSEGRAhlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQinsLFPQNGNVVNFAS 265
Cdd:TIGR00785 144 ------------PEKSPRKIGKY------------LMLGIAYSASIGSSGFLTGSAPNALAAGI---LSKILGIQISWGD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 266 WFSFAFPTMVILLLLAWLWLQILFLGfnfrknfgigEKMQEQQQAAycVIQTEHRLLGPMTFAEKAISILFVILVLLWFT 345
Cdd:TIGR00785 197 WFLAGLPLGIILLLLVPLLLYVLFPP----------ELKLKDEVDL--WAKEELEEMGPMSFREKALLGIFLLALLLWIF 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 346 repGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpenpgklkapLGLLDWKTVNQ-KMPWNIVLL 424
Cdd:TIGR00785 265 ---GGSLG--------------INASVVALLAVVLMLF---------------------LGIVTWKDIQKnKVAWNTLIL 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 425 LGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATF--TECTSNVATTTIFLPILASMAQAICLHPLYVM 502
Cdd:TIGR00785 307 FGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIilYFFASNTAHTAALVPIFFSVASAQGIPLELLA 386
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 4506979 503 LPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 558
Cdd:TIGR00785 387 LALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLW 443
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
6-565 |
7.94e-134 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 399.05 E-value: 7.94e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 6 QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDA----SEVAVE 81
Cdd:pfam00939 1 LTLWWKLLALLAVLLIILLLPAPDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 82 YLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPapLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHS 161
Cdd:pfam00939 81 FSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 162 SqassnveegsNNPTFELQEPSpqkevtkldngqalpvtsassegrahlsqkhlHLTQCMSLCVCYSASIGGIATLTGTA 241
Cdd:pfam00939 159 A----------FGSDPEKGSER--------------------------------RIGAYLMWTVYQSTSITSAMFLTAMA 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 242 PNLVLQGQINSlfpQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNfgigekmqeqqqAAYCVIQTEHRL 321
Cdd:pfam00939 197 PNLLLLGLMNS---ILGVTITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSVP------------DAKAIAKTELKE 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 322 LGPMTFAEKAISILFVILVLLWFTRepgfflgwgnlafpnakGESMVSDGTVAIFIGIIMFIipskfpgltqdpenpgkl 401
Cdd:pfam00939 262 LGPMTFREKALLGLFVLLLLLWIFG-----------------GSLNIDATTVAIIGLALMLL------------------ 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 402 kapLGLLDWK-TVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQS--VPAPAIAIILSLLVATFTECTSNVA 478
Cdd:pfam00939 307 ---LRILDWKdIVKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSgfSPAMAFIIILSLFYLSHYLFASATA 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 479 TTTIFLPILASMAQAICLHP-LYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAIN 556
Cdd:pfam00939 384 HTAAMLPIFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGN 463
|
....*....
gi 4506979 557 SWGIPLFSL 565
Cdd:pfam00939 464 WWWKPLGSL 472
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
39-559 |
2.42e-92 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 289.10 E-value: 2.42e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 39 AYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalp 198
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP----------------------------------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 199 vtsassegrahlsqkhlhltQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNvvnFASWFSFAFPTMVIll 278
Cdd:cd01115 126 --------------------SRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQGFS---FFEFTPIGLPLLII-- 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 279 llawlwlqilflgfnfrknfgigekmqeqqqaaycviqtehrllgpmtfaekaisilfVILVLLWFTREPGFFLGWGNLA 358
Cdd:cd01115 181 ----------------------------------------------------------GLLYLWFIFRLAVLIITIVLLA 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 359 FPNA-KGESMVSDGTVAIFIGIIMFiipskfpgltqdpenpgklkaplGLLDWKTVNQKMPWNIVLLLGGGYALAKGSER 437
Cdd:cd01115 203 ALAAiTGLLPVSVAIAIGAIVLVFG-----------------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALES 259
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 438 SGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLP 516
Cdd:cd01115 260 SGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLP 339
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 4506979 517 VATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWG 559
Cdd:cd01115 340 VGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
91-558 |
2.93e-75 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 243.91 E-value: 2.93e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 91 FGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSsqassnvEE 170
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGS-------EK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 171 GSNNPTFelqepspqkevtkldngqalpvtsassegrahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQI 250
Cdd:COG0471 74 RSKFGSA-------------------------------------------LLLPIAFAASIGGMGTLIGTPPNLIAAGLL 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 251 NSLFPQNgnvVNFASWFSFAFPTMVILLLLAWLwlqilFLGFNFRKNFGIGEKMQEqqqaaycVIQTEHRLLGPMTFAEK 330
Cdd:COG0471 111 EEATGIP---ISFFEWMLVGLPVALVGLLLLWL-----VLYRLLPPEIKEVPGSKE-------VIREELAELGPLSRREK 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 331 AISILFVILVLLWFTrepGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpenpgklkapLGLLDW 410
Cdd:COG0471 176 IALAIFALTVLLWIT---GSLHG--------------IPIAVVALLGAVLLLL---------------------TGVLTW 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 411 KTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTP-LQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILAS 489
Cdd:COG0471 218 KDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAIS 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 4506979 490 MAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 558
Cdd:COG0471 298 LAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
33-558 |
6.33e-48 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 173.30 E-value: 6.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 33 SKEAYCAYAI-ILMALFWCTEALPLAVTALFP-LILFPMMGIVDASEV--AVEYLKDSNL-LFFGGLLVAIAVEHWNLHK 107
Cdd:TIGR00785 7 NSGAWLLLAIfVAAIVGWILEPLPLPVTALLAiPIIAVLLGVLSAFKFknALSGFADPTIwLFFGAFILATALVKTGLGK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 108 RIALRVLLIVGVRPAPL-ILGFMLVTAFLSMWISNTA-TSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqepspq 185
Cdd:TIGR00785 87 RIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLPLLGSK----------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 186 kevtkldngqalPVTSASSEGRAhlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQinsLFPQNGNVVNFAS 265
Cdd:TIGR00785 144 ------------PEKSPRKIGKY------------LMLGIAYSASIGSSGFLTGSAPNALAAGI---LSKILGIQISWGD 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 266 WFSFAFPTMVILLLLAWLWLQILFLGfnfrknfgigEKMQEQQQAAycVIQTEHRLLGPMTFAEKAISILFVILVLLWFT 345
Cdd:TIGR00785 197 WFLAGLPLGIILLLLVPLLLYVLFPP----------ELKLKDEVDL--WAKEELEEMGPMSFREKALLGIFLLALLLWIF 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 346 repGFFLGwgnlafpnakgesmVSDGTVAIFIGIIMFIipskfpgltqdpenpgklkapLGLLDWKTVNQ-KMPWNIVLL 424
Cdd:TIGR00785 265 ---GGSLG--------------INASVVALLAVVLMLF---------------------LGIVTWKDIQKnKVAWNTLIL 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 425 LGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATF--TECTSNVATTTIFLPILASMAQAICLHPLYVM 502
Cdd:TIGR00785 307 FGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLFYIilYFFASNTAHTAALVPIFFSVASAQGIPLELLA 386
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 4506979 503 LPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSW 558
Cdd:TIGR00785 387 LALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLW 443
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
46-555 |
1.95e-42 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 157.03 E-value: 1.95e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 46 ALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIvGVRPAPLI 125
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARA-SKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 126 LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQassnveegsnnptfelqepspqkevtkldngqalpvtsasse 205
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP------------------------------------------ 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 206 grahlsqkhlhlTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINslfpqngnvVNFASWFSFAFPTMVILLLLAWLWL 285
Cdd:cd00625 118 ------------PVPLLLALAFAANIGGAATPIGNPPNLIIASLSG---------LGFLDFLAFMAPPALGLLLLLLGLL 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 286 QILFLGFNFRKNFGIGEKMQEQQQAAYcviqtehrllgpmTFAEKAISILFVILVLLWFtrepGFFLGWGNLafpnakge 365
Cdd:cd00625 177 YLLFRKKLLLPDEDKLTVLAEPLPARP-------------LLKKFLLLALLLLLLFVLL----FFFLIPLGL-------- 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 366 sMVSDGTVAIFIGIIMFiipskfpgltqdpenpgklkaplglLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLG 445
Cdd:cd00625 232 -IALLGALLLLLLLVRG-------------------------LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLA 285
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 446 NKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASM-----AQAICLHPLYVMLPCTLATSLAFMLPVATP 520
Cdd:cd00625 286 ELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLappepAWLALALGSTLGGNLTLIGSLANLIPLGAA 365
|
490 500 510
....*....|....*....|....*....|....*
gi 4506979 521 PNAIVfsfgDLKVLDMARAGFLLNIIGVLIIALAI 555
Cdd:cd00625 366 ENAGV----GISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
46-503 |
6.48e-26 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 108.94 E-value: 6.48e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 46 ALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLI 125
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 126 LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSqassnveegsnnptfelqePSPqkevtkldngqalpvtsasse 205
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP-------------------PSP--------------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 206 grahlsqkhlhltqcMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVillllawlwl 285
Cdd:pfam03600 121 ---------------LLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLL---------- 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 286 qilFLGFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGpmtfaekaisILFVILVLLWFTREPGFFLGWGNLAfpnakge 365
Cdd:pfam03600 176 ---PLLLIFRKLLPVRKEEEAELEELRKRAIKDKLLLA----------ISALVLALVILGFLLLSVLALAGAL------- 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 366 smvsdgtvaifigiimfiipskfpgltqdpenpgkLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLG 445
Cdd:pfam03600 236 -----------------------------------LLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALA 280
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 4506979 446 NKLTPLqsVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVML 503
Cdd:pfam03600 281 DALGGL--SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
404-555 |
3.46e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.94 E-value: 3.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 404 PLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIF 483
Cdd:pfam03600 24 LLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIM 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4506979 484 LPILASMAQAICLHPLYVMLPCTLATSLAFML-PVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 555
Cdd:pfam03600 104 IPIVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
42-160 |
1.74e-08 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 56.70 E-value: 1.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 42 IILMALFWCTEA---LPLAVTALFPLILFPMMGIVDASEvAVEYLKDSNLLFFGGLL-VAIAVEHWNLHKRIALRVL-LI 116
Cdd:COG0471 181 FALTVLLWITGSlhgIPIAVVALLGAVLLLLTGVLTWKD-AYKSIPWGVLLLFGGGLaLGAALEKTGLAAWLADALLpLL 259
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 4506979 117 VGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLH 160
Cdd:COG0471 260 GGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALG 303
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
405-555 |
1.34e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 53.98 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 405 LGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFL 484
Cdd:COG1055 39 LGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLT 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4506979 485 PILASMAQAICLHPLYVMLPCTLATSLA-FMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAI 555
Cdd:COG1055 119 PVVLAIARRLGLNPVPFLIAIVFAANIGgAATPIGNPTNIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVL 190
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
420-562 |
2.24e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 53.36 E-value: 2.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 420 NIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPL 499
Cdd:cd01115 47 PAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPS 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 500 YVMLPCTLATSLAFML-PVATPPNAIV------FSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPL 562
Cdd:cd01115 127 RLLMPLAFAASIGGMLtLIGTPPNLVAsgylesLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAVLII 196
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
8-165 |
3.49e-07 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 52.31 E-value: 3.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 8 LWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSN 87
Cdd:pfam03600 178 LLIFRKLLPVRKEEEAELEELRKRAIKDKLLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTL 257
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4506979 88 LLFFGGLLVAIAVEHWNLHKRIAlrVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQAS 165
Cdd:pfam03600 258 LFFAGLFILVGALEKTGLADALA--DALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPD 333
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
41-159 |
4.38e-05 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 46.27 E-value: 4.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 41 AIILMALFWctEALPLAVTALFPLILFPMMGIVDASEvAVEYLkDSNLLFF--GGLLVAIAVEHWNLHKRIALRVLLIVG 118
Cdd:COG1055 12 TYLLIILEP--RGLNRAVAALLGAALLLLLGVVSLED-ALEAI-DWNTILFllGMMIIVAILDESGFFEWLAIKLARRAK 87
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 4506979 119 VRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQL 159
Cdd:COG1055 88 GSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRL 128
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
41-154 |
4.58e-05 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 46.09 E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4506979 41 AIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLV-AIAVEHWNLHKRIALRVLLIVGV 119
Cdd:cd00625 215 LLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVlVGALESTGLLEWLAELLVALVGL 294
|
90 100 110
....*....|....*....|....*....|....*
gi 4506979 120 RPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHA 154
Cdd:cd00625 295 PPLAALLLIGLLSALLSNFISNVPTVALLLPIAAS 329
|
|
| |
