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delta(14)-sterol reductase TM7SF2 isoform 1 [Homo sapiens]
phosphatidylethanolamine N-methyltransferase family domain-containing protein( domain architecture ID 229533)
phosphatidylethanolamine N-methyltransferase (PEMT) family domain-containing protein similar to Homo sapiens PEMT, which catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC)
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||||
ICMT super family | cl21511 | Isoprenylcysteine carboxyl methyltransferase (ICMT) family; The isoprenylcysteine ... |
73-418 | 5.82e-142 | ||||||
Isoprenylcysteine carboxyl methyltransferase (ICMT) family; The isoprenylcysteine o-methyltransferase (EC:2.1.1.100) family carry out carboxyl methylation of cleaved eukaryotic proteins that terminate in a CaaX motif. In Saccharomyces cerevisiae this methylation is carried out by Ste14p, an integral endoplasmic reticulum membrane protein. Ste14p is the founding member of the isoprenylcysteine carboxyl methyltransferase (ICMT) family, whose members share significant sequence homology. The actual alignment was detected with superfamily member pfam01222: Pssm-ID: 473892 Cd Length: 429 Bit Score: 411.45 E-value: 5.82e-142
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Name | Accession | Description | Interval | E-value | ||||||
ERG4_ERG24 | pfam01222 | Ergosterol biosynthesis ERG4/ERG24 family; |
73-418 | 5.82e-142 | ||||||
Ergosterol biosynthesis ERG4/ERG24 family; Pssm-ID: 250456 Cd Length: 429 Bit Score: 411.45 E-value: 5.82e-142
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STE14 | COG2020 | Protein-S-isoprenylcysteine O-methyltransferase Ste14 [Posttranslational modification, protein ... |
334-417 | 2.43e-10 | ||||||
Protein-S-isoprenylcysteine O-methyltransferase Ste14 [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 441623 [Multi-domain] Cd Length: 113 Bit Score: 57.48 E-value: 2.43e-10
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Name | Accession | Description | Interval | E-value | ||||||
ERG4_ERG24 | pfam01222 | Ergosterol biosynthesis ERG4/ERG24 family; |
73-418 | 5.82e-142 | ||||||
Ergosterol biosynthesis ERG4/ERG24 family; Pssm-ID: 250456 Cd Length: 429 Bit Score: 411.45 E-value: 5.82e-142
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STE14 | COG2020 | Protein-S-isoprenylcysteine O-methyltransferase Ste14 [Posttranslational modification, protein ... |
334-417 | 2.43e-10 | ||||||
Protein-S-isoprenylcysteine O-methyltransferase Ste14 [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 441623 [Multi-domain] Cd Length: 113 Bit Score: 57.48 E-value: 2.43e-10
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COG3752 | COG3752 | Steroid 5-alpha reductase family enzyme [General function prediction only]; |
269-410 | 2.08e-03 | ||||||
Steroid 5-alpha reductase family enzyme [General function prediction only]; Pssm-ID: 442966 Cd Length: 264 Bit Score: 39.82 E-value: 2.08e-03
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Blast search parameters | ||||
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