succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform 1 precursor [Homo sapiens]
succinate:quinone oxidoreductase subunit C( domain architecture ID 10131276)
succinate:quinone oxidoreductase transmembrane subunit C, together with the D subunit, acts to anchor the catalytic components of succinate dehydrogenase to the cytoplasmic membrane
List of domain hits
Name | Accession | Description | Interval | E-value | |||
SQR_TypeC_SdhC | cd03499 | Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) ... |
50-152 | 6.62e-34 | |||
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this family reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Proteins in this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. The heme and quinone binding sites reside in the transmembrane subunits. The SdhC or CybL protein is one of the two transmembrane subunits of bacterial and eukaryotic SQRs. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes. : Pssm-ID: 239579 Cd Length: 117 Bit Score: 115.71 E-value: 6.62e-34
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Name | Accession | Description | Interval | E-value | |||
SQR_TypeC_SdhC | cd03499 | Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) ... |
50-152 | 6.62e-34 | |||
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this family reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Proteins in this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. The heme and quinone binding sites reside in the transmembrane subunits. The SdhC or CybL protein is one of the two transmembrane subunits of bacterial and eukaryotic SQRs. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes. Pssm-ID: 239579 Cd Length: 117 Bit Score: 115.71 E-value: 6.62e-34
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SdhC | COG2009 | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit [Energy production and ... |
48-152 | 5.17e-21 | |||
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit [Energy production and conversion]; Pssm-ID: 441612 Cd Length: 128 Bit Score: 82.91 E-value: 5.17e-21
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Sdh_cyt | pfam01127 | Succinate dehydrogenase/Fumarate reductase transmembrane subunit; This family includes a ... |
49-152 | 2.06e-20 | |||
Succinate dehydrogenase/Fumarate reductase transmembrane subunit; This family includes a transmembrane protein from both the Succinate dehydrogenase and Fumarate reductase complexes. Pssm-ID: 426067 Cd Length: 122 Bit Score: 81.28 E-value: 2.06e-20
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succ_dehyd_cytB | TIGR02970 | succinate dehydrogenase, cytochrome b556 subunit; In E. coli and many other bacteria, two ... |
48-152 | 5.96e-18 | |||
succinate dehydrogenase, cytochrome b556 subunit; In E. coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase, a TCA cycle enzyme, are SdhC and SdhD. This family is the SdhC, the cytochrome b subunit, called b556 in bacteria and b560 in mitochondria. SdhD (see TIGR02968) is called the hydrophobic membrane anchor subunit, although both SdhC and SdhD participate in anchoring the complex. In some bacteria, this cytochrome b subunit is replaced my a member of the cytochrome b558 family (see TIGR02046). [Energy metabolism, TCA cycle] Pssm-ID: 274370 Cd Length: 120 Bit Score: 74.91 E-value: 5.96e-18
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PLN00127 | PLN00127 | succinate dehydrogenase (ubiquinone) cytochrome b subunit; Provisional |
48-138 | 2.96e-16 | |||
succinate dehydrogenase (ubiquinone) cytochrome b subunit; Provisional Pssm-ID: 177738 Cd Length: 178 Bit Score: 72.22 E-value: 2.96e-16
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Name | Accession | Description | Interval | E-value | |||
SQR_TypeC_SdhC | cd03499 | Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) ... |
50-152 | 6.62e-34 | |||
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this family reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Proteins in this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. The heme and quinone binding sites reside in the transmembrane subunits. The SdhC or CybL protein is one of the two transmembrane subunits of bacterial and eukaryotic SQRs. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes. Pssm-ID: 239579 Cd Length: 117 Bit Score: 115.71 E-value: 6.62e-34
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SdhC | COG2009 | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit [Energy production and ... |
48-152 | 5.17e-21 | |||
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit [Energy production and conversion]; Pssm-ID: 441612 Cd Length: 128 Bit Score: 82.91 E-value: 5.17e-21
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Sdh_cyt | pfam01127 | Succinate dehydrogenase/Fumarate reductase transmembrane subunit; This family includes a ... |
49-152 | 2.06e-20 | |||
Succinate dehydrogenase/Fumarate reductase transmembrane subunit; This family includes a transmembrane protein from both the Succinate dehydrogenase and Fumarate reductase complexes. Pssm-ID: 426067 Cd Length: 122 Bit Score: 81.28 E-value: 2.06e-20
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succ_dehyd_cytB | TIGR02970 | succinate dehydrogenase, cytochrome b556 subunit; In E. coli and many other bacteria, two ... |
48-152 | 5.96e-18 | |||
succinate dehydrogenase, cytochrome b556 subunit; In E. coli and many other bacteria, two small, hydrophobic, mutually homologous subunits of succinate dehydrogenase, a TCA cycle enzyme, are SdhC and SdhD. This family is the SdhC, the cytochrome b subunit, called b556 in bacteria and b560 in mitochondria. SdhD (see TIGR02968) is called the hydrophobic membrane anchor subunit, although both SdhC and SdhD participate in anchoring the complex. In some bacteria, this cytochrome b subunit is replaced my a member of the cytochrome b558 family (see TIGR02046). [Energy metabolism, TCA cycle] Pssm-ID: 274370 Cd Length: 120 Bit Score: 74.91 E-value: 5.96e-18
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PLN00127 | PLN00127 | succinate dehydrogenase (ubiquinone) cytochrome b subunit; Provisional |
48-138 | 2.96e-16 | |||
succinate dehydrogenase (ubiquinone) cytochrome b subunit; Provisional Pssm-ID: 177738 Cd Length: 178 Bit Score: 72.22 E-value: 2.96e-16
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SQR_QFR_TM | cd03493 | Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, ... |
69-152 | 1.14e-10 | |||
Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR, also called succinate dehydrogenase or Complex II, is part of the citric acid cycle and the aerobic respiratory chain, while QFR is involved in anaerobic respiration with fumarate as the terminal electron acceptor. SQRs may reduce either high or low potential quinones while QFRs oxidize only low potential quinols. SQR and QFR share a common subunit arrangement, composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centers, and the transmembrane subunit(s) containing the electron donor/acceptor (quinol or quinone). The reversible reduction of quinone is an essential feature of respiration, allowing the transfer of electrons between respiratory complexes. SQRs and QFRs can be classified into five types (A-E) according to the number of their hydrophobic subunits and heme groups. This classification is consistent with the characteristics and phylogeny of the catalytic and iron-sulfur subunits. Type E proteins, e.g. non-classical archael SQRs, contain atypical transmembrane subunits and are not included in this hierarchy. The heme and quinone binding sites reside in the transmembrane subunits. Although succinate oxidation and fumarate reduction are carried out by separate enzymes in most organisms, some bifunctional enzymes that exhibit both SQR and QFR activities exist. Pssm-ID: 239573 Cd Length: 98 Bit Score: 55.36 E-value: 1.14e-10
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PLN00130 | PLN00130 | succinate dehydrogenase (SDH3); Provisional |
48-117 | 1.91e-03 | |||
succinate dehydrogenase (SDH3); Provisional Pssm-ID: 177741 [Multi-domain] Cd Length: 213 Bit Score: 37.43 E-value: 1.91e-03
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PLN00126 | PLN00126 | succinate dehydrogenase, cytochrome b subunit family; Provisional |
48-82 | 5.64e-03 | |||
succinate dehydrogenase, cytochrome b subunit family; Provisional Pssm-ID: 165695 Cd Length: 129 Bit Score: 35.13 E-value: 5.64e-03
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Blast search parameters | ||||
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