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Conserved domains on  [gi|1909429727|ref|NP_001374190|]
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protein PAT1 homolog 2 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
263-413 4.24e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 56.20  E-value: 4.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 263 IEGSLGQVAVSTCFSPR---------------RAIDAVPHGTQEqdiEAASSQRLRVLYRIEKMFLQLLEIEEGWKYRPP 327
Cdd:pfam09770 497 IEGSLGKISFSNAKTPKpllnikrpessndahRPGSAKKQRSHS---ETFSLDRKTILRNIEKVYDTLMKMEDHERKMPP 573
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 328 PPC-FSEQQSNQV------------EKLFQTLKTQEQNNlEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAIT 394
Cdd:pfam09770 574 PPTeDSDPELIEKhmewrstlqalnAKLWQELKVHEPIG-STTPHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIV 652
                         170       180
                  ....*....|....*....|.
gi 1909429727 395 HHLPLL--VRRDVADQALQML 413
Cdd:pfam09770 653 VHLDQLdvVRGAQVTDGETQL 673
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
263-413 4.24e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 56.20  E-value: 4.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 263 IEGSLGQVAVSTCFSPR---------------RAIDAVPHGTQEqdiEAASSQRLRVLYRIEKMFLQLLEIEEGWKYRPP 327
Cdd:pfam09770 497 IEGSLGKISFSNAKTPKpllnikrpessndahRPGSAKKQRSHS---ETFSLDRKTILRNIEKVYDTLMKMEDHERKMPP 573
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 328 PPC-FSEQQSNQV------------EKLFQTLKTQEQNNlEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAIT 394
Cdd:pfam09770 574 PPTeDSDPELIEKhmewrstlqalnAKLWQELKVHEPIG-STTPHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIV 652
                         170       180
                  ....*....|....*....|.
gi 1909429727 395 HHLPLL--VRRDVADQALQML 413
Cdd:pfam09770 653 VHLDQLdvVRGAQVTDGETQL 673
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
263-413 4.24e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 56.20  E-value: 4.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 263 IEGSLGQVAVSTCFSPR---------------RAIDAVPHGTQEqdiEAASSQRLRVLYRIEKMFLQLLEIEEGWKYRPP 327
Cdd:pfam09770 497 IEGSLGKISFSNAKTPKpllnikrpessndahRPGSAKKQRSHS---ETFSLDRKTILRNIEKVYDTLMKMEDHERKMPP 573
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1909429727 328 PPC-FSEQQSNQV------------EKLFQTLKTQEQNNlEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAIT 394
Cdd:pfam09770 574 PPTeDSDPELIEKhmewrstlqalnAKLWQELKVHEPIG-STTPHPFIAFLSHPKGKKAIPRIFRHLSQEQRTTILTMIV 652
                         170       180
                  ....*....|....*....|.
gi 1909429727 395 HHLPLL--VRRDVADQALQML 413
Cdd:pfam09770 653 VHLDQLdvVRGAQVTDGETQL 673
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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