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Conserved domains on  [gi|1270111312|ref|NP_001344289|]
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jhy protein isoform b [Mus musculus]

Protein Classification

Jhy family protein( domain architecture ID 10633721)

Jhy family protein is a DUF4591 domain-containing protein, similar to Mus musculus Jhy (juvenile hydrocephalus) protein that is required for the normal development of cilia in brain ependymal cells lining the ventricular surfaces

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
JHY pfam15261
Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as ...
 648-767 6.51e-42

Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as 4931429I11Rik). This protein family is found in eukaryotes, and is approximately 120 amino acids in length. In humans, the gene encoding this protein lies in the position chromosome 11 open reading frame 63.


:

Pssm-ID: 464601  Cd Length: 126  Bit Score: 148.76  E-value: 6.51e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111312 648 KLGGLGPDFASVRDKMQMLMQQKEYAQQVKDYNMKALSILSKPQTSKTESKSAISRKKALDYAKTIPKPKPPNLPDQT-- 725
Cdd:pfam15261   1 KLGGLGPDLDEYKEKLEKLKRQKEYAKQVREQNMKTLPIRSQPNTKKPEEKDQVSRRKALEYAKTIPKPKPVVKPQQYpe 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1270111312 726 ----AKKTKNSRHSEKEGGLPEISLLEILQSRHEREKQAVAAFKVL 767
Cdd:pfam15261  81 adakLKMERHRAGPQKPVDLPEISLLEKLQSRHEKEKQAVAAFRQL 126
 
Name Accession Description Interval E-value
JHY pfam15261
Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as ...
 648-767 6.51e-42

Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as 4931429I11Rik). This protein family is found in eukaryotes, and is approximately 120 amino acids in length. In humans, the gene encoding this protein lies in the position chromosome 11 open reading frame 63.


Pssm-ID: 464601  Cd Length: 126  Bit Score: 148.76  E-value: 6.51e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111312 648 KLGGLGPDFASVRDKMQMLMQQKEYAQQVKDYNMKALSILSKPQTSKTESKSAISRKKALDYAKTIPKPKPPNLPDQT-- 725
Cdd:pfam15261   1 KLGGLGPDLDEYKEKLEKLKRQKEYAKQVREQNMKTLPIRSQPNTKKPEEKDQVSRRKALEYAKTIPKPKPVVKPQQYpe 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1270111312 726 ----AKKTKNSRHSEKEGGLPEISLLEILQSRHEREKQAVAAFKVL 767
Cdd:pfam15261  81 adakLKMERHRAGPQKPVDLPEISLLEKLQSRHEKEKQAVAAFRQL 126
 
Name Accession Description Interval E-value
JHY pfam15261
Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as ...
 648-767 6.51e-42

Jhy protein; Jhy protein is the protein product of the gene Jhy (previously known as 4931429I11Rik). This protein family is found in eukaryotes, and is approximately 120 amino acids in length. In humans, the gene encoding this protein lies in the position chromosome 11 open reading frame 63.


Pssm-ID: 464601  Cd Length: 126  Bit Score: 148.76  E-value: 6.51e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111312 648 KLGGLGPDFASVRDKMQMLMQQKEYAQQVKDYNMKALSILSKPQTSKTESKSAISRKKALDYAKTIPKPKPPNLPDQT-- 725
Cdd:pfam15261   1 KLGGLGPDLDEYKEKLEKLKRQKEYAKQVREQNMKTLPIRSQPNTKKPEEKDQVSRRKALEYAKTIPKPKPVVKPQQYpe 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1270111312 726 ----AKKTKNSRHSEKEGGLPEISLLEILQSRHEREKQAVAAFKVL 767
Cdd:pfam15261  81 adakLKMERHRAGPQKPVDLPEISLLEKLQSRHEKEKQAVAAFRQL 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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