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Conserved domains on  [gi|665505991|ref|NP_001287832|]
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complement decay-accelerating factor isoform 6 precursor [Homo sapiens]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 13884057)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 98-280 3.98e-37

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 136.32  E-value: 3.98e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSPKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927  21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 175 DVpGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927  98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                        170       180
                 ....*....|....*....|....*..
gi 665505991 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927 177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 1.85e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 1.85e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991    36 CGLPPDVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-280 3.98e-37

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 136.32  E-value: 3.98e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSPKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927  21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 175 DVpGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927  98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                        170       180
                 ....*....|....*....|....*..
gi 665505991 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927 177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 1.33e-16

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 73.65  E-value: 1.33e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNndeGEWSGPPPECR 284
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 1.05e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 65.24  E-value: 1.05e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991   225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 9.85e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.52  E-value: 9.85e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991  225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQ---EDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 1.85e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 1.85e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991    36 CGLPPDVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 7.40e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.52  E-value: 7.40e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991  36 CGLPPDVPNAQPALeGRTSFPEDTVITYKCEESFVKIPgeKDSVICLKGSQWSDIEEFC 94
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-280 3.98e-37

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 136.32  E-value: 3.98e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991  98 CEVPTRLNSASLK---QPYITQNYfPVGTVVEYECRPGYRREPSLSPKLTCLQNlKWsTAVEFCKKKSCPNPGEIRNGQI 174
Cdd:PHA02927  21 CTIPSRPINMKFKnsvETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GW-TLFNQCIKRRCPSPRDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 175 DVpGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Cdd:PHA02927  98 DI-GGVDFGSSITYSCNSGYQLIGESKSYCeLGSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSC 176

                        170       180
                 ....*....|....*....|....*..
gi 665505991 254 NKGFTMIGEHSIYCTvnndEGEWSGPP 280
Cdd:PHA02927 177 NSGYSLIGNSGVLCS----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 1.33e-16

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 73.65  E-value: 1.33e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNndeGEWSGPPPECR 284
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 1.05e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 65.24  E-value: 1.05e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991   225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 159-284 5.68e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 69.31  E-value: 5.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 159 KKKSCPNPGEIRNGQI-DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ 237
Cdd:PHA02639  18 KSIYCDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 665505991 238 GERDHYGYRQSVTYACN--KG--FTMIGEHSIYCTvnnDEGEWSGPPPECR 284
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNehKGvqYSLVGNEKITCI---QDKSWKPDPPICK 145
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 9.85e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 62.52  E-value: 9.85e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991  225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTvnnDEGEWSGPPPEC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQ---EDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
98-158 2.61e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.66  E-value: 2.61e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665505991   98 CEVPTRLNSASLkqpYITQNYFPVGTVVEYECRPGYRREPslSPKLTCLQNLKWSTAVEFC 158
Cdd:pfam00084   1 CPPPPDIPNGKV---SATKNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 163-221 3.50e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 3.50e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 163 CPNPGEIRNGQIDVPGGI-LFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPECR 221
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENG---GWSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 119-283 1.33e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 61.99  E-value: 1.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 119 FPVGTVVEYECRPGYrrePSLSPKL-TCLQ---NLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCN-- 191
Cdd:PHA02639  40 YEIGKLIEYTCNTDY---ALIGDRFrTCIKdknNAIWSNKAPFCMLKECNDPPSIINGKIYNKREMYkVGDEIYYVCNeh 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 192 --TGYKLFGSTSSFCLISGSsvqWSDPLPECREIYCPApPQIDNGIIQG--ERDHYGYRQSVTYACNKGFTMIGEHSIYC 267
Cdd:PHA02639 117 kgVQYSLVGNEKITCIQDKS---WKPDPPICKMINCRF-PALQNGYINGipSNKKFYYKTRVGFSCKSGFDLVGEKYSTC 192

                        170
                 ....*....|....*.
gi 665505991 268 TVNndeGEWSGPPPEC 283
Cdd:PHA02639 193 NIN---ATWFPSIPTC 205
PHA02831 PHA02831
EEV host range protein; Provisional
 125-294 1.68e-10

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 61.55  E-value: 1.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 125 VEYECRPGYRrepslSPKLTClQNLKWSTAVEFCKKKSCPNPGEIRNGQI-DVPGGILFGATISFSCNTG----YKLFGS 199
Cdd:PHA02831  46 LEYKCNNNFD-----KVFVTC-NNGSWSTKNMCIGKRNCKDPVTILNGYIkNKKDQYSFGDSVTYACKVNklekYSIVGN 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 200 TSSFClISGssvQWSDPLPECREIYCPAPPqIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNdegEWSGP 279
Cdd:PHA02831 120 ETVKC-INK---QWVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINS---IWYPG 191

                        170
                 ....*....|....*
gi 665505991 280 PPECRGKSLTSKVPP 294
Cdd:PHA02831 192 IPKCVKDKVHNEIQP 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 163-220 4.37e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 4.37e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991   163 CPNPGEIRNGQIDVPGG-ILFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPEC 220
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCLENG---TWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 157-283 1.58e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 54.95  E-value: 1.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 157 FCKKKSCPNPGEIRNGQI-DVPGGILFGATISFSCNTG-----YKLFGSTSSFCLISGssvQWSDPLPECREIYCPAPPq 230
Cdd:PHA02817  18 LCDLNKCCYPPSIKNGYIyNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDG---KWNKEFPVCKIIRCRFPA- 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 665505991 231 IDNGIIQGERDH--YGYRQSVTYACNKGFTMIGEHSIYCTVNNdegEWSGPPPEC 283
Cdd:PHA02817  94 LQNGFVNGIPDSkkFYYESEVSFSCKPGFVLIGTKYSVCGINS---SWIPKVPIC 145
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 98-159 1.31e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 1.31e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 665505991  98 CEVPTRLNSASLKqpyITQNYFPVGTVVEYECRPGYRREPslSPKLTCLQNLKWSTAVEFCK 159
Cdd:cd00033    1 CPPPPVPENGTVT---GSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
163-220 2.62e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 2.62e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991  163 CPNPGEIRNGQIDVPGGI-LFGATISFSCNTGYKLFGSTSSFCLISGssvQWSDPLPEC 220
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEyNYGASVSYECDPGYRLVGSPTITCQEDG---TWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 115-158 7.07e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 43.28  E-value: 7.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 665505991   115 TQNYFPVGTVVEYECRPGYRREPslSPKLTCLQNLKWSTAVEFC 158
Cdd:smart00032  15 SSGTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 220-284 7.86e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.86  E-value: 7.86e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 220 CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCtvnNDEGEWSGPPPECR 284
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIIC---EKDGKWNKEFPVCK 85
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 1.85e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 1.85e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991    36 CGLPPDVPNAQPALeGRTSFPEDTVITYKCEESFVKIPGEkdSVICLKGSQWSDIEEFC 94
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSS--TITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 7.40e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.52  E-value: 7.40e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 665505991  36 CGLPPDVPNAQPALeGRTSFPEDTVITYKCEESFVKIPgeKDSVICLKGSQWSDIEEFC 94
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 97-271 1.16e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 43.92  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991  97 SCEVPTrLNSASLKQpyiTQNYFPVGTVVEYECRPGYRrepSLSPKLTClQNLKWSTAvEFCKKKSCPNP--GEIRNGQI 174
Cdd:PHA02954  20 TCTVPT-MNNAKLTS---TETSFNDKQKVTFTCDSGYY---SLDPNAVC-ETDKWKYE-NPCKKMCTVSDyvSELYDKPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665505991 175 dvpggILFGATISFSCNTGYKLFGstssfCLISGSSVQWSD----PLPECReiycpaPPQIDNGIIQGERDHYGYRQSVT 250
Cdd:PHA02954  91 -----YEVNSTITLICKDETKYFR-----CEEKNGNTSWNDtvtcPNAECQ------PLQLEHGSCQPVKEKYSFGEHIT 154

                        170       180
                 ....*....|....*....|.
gi 665505991 251 YACNKGFTMIGEHSIYCTVNN 271
Cdd:PHA02954 155 INCDVGYEVIGASYISCTANS 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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