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Conserved domains on  [gi|665390809|ref|NP_001285135|]
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uncharacterized protein Dmel_CG2444, isoform B [Drosophila melanogaster]

Protein Classification

SVWC domain-containing protein( domain architecture ID 10634203)

SVWC domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SVWC pfam15430
Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand ...
 42-110 7.46e-17

Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand factor type C proteins from lower eukaryotes. The canonical pattern of most von Willebrand factor type C (VWC) domains is of ten cysteines, however this family, largely but not exclusively of arthropod proteins, contains only eight. SVWC family proteins respond to environmental challenges, such as bacterial infection and nutritional status. They also are involved in anti-viral immunity, and all of these functions seem linked to SVWC expression being induced by Dicer2.


:

Pssm-ID: 464713  Cd Length: 66  Bit Score: 68.58  E-value: 7.46e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665390809   42 CVLDTNTILSPGETGLAPDlPCVRAECHADGLVTFKTCDAVAPPPGCKQRDFvNINREFPACCeRKYNC 110
Cdd:pfam15430   1 CYYEENLTLKPGESYKPPG-PCERITCGADGSLTIETCGVVALPPNCKLGEY-DPTKPYPECC-PKYKC 66
 
Name Accession Description Interval E-value
SVWC pfam15430
Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand ...
 42-110 7.46e-17

Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand factor type C proteins from lower eukaryotes. The canonical pattern of most von Willebrand factor type C (VWC) domains is of ten cysteines, however this family, largely but not exclusively of arthropod proteins, contains only eight. SVWC family proteins respond to environmental challenges, such as bacterial infection and nutritional status. They also are involved in anti-viral immunity, and all of these functions seem linked to SVWC expression being induced by Dicer2.


Pssm-ID: 464713  Cd Length: 66  Bit Score: 68.58  E-value: 7.46e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665390809   42 CVLDTNTILSPGETGLAPDlPCVRAECHADGLVTFKTCDAVAPPPGCKQRDFvNINREFPACCeRKYNC 110
Cdd:pfam15430   1 CYYEENLTLKPGESYKPPG-PCERITCGADGSLTIETCGVVALPPNCKLGEY-DPTKPYPECC-PKYKC 66
 
Name Accession Description Interval E-value
SVWC pfam15430
Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand ...
 42-110 7.46e-17

Single domain von Willebrand factor type C; SVWC is a family of single-domain von Willebrand factor type C proteins from lower eukaryotes. The canonical pattern of most von Willebrand factor type C (VWC) domains is of ten cysteines, however this family, largely but not exclusively of arthropod proteins, contains only eight. SVWC family proteins respond to environmental challenges, such as bacterial infection and nutritional status. They also are involved in anti-viral immunity, and all of these functions seem linked to SVWC expression being induced by Dicer2.


Pssm-ID: 464713  Cd Length: 66  Bit Score: 68.58  E-value: 7.46e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665390809   42 CVLDTNTILSPGETGLAPDlPCVRAECHADGLVTFKTCDAVAPPPGCKQRDFvNINREFPACCeRKYNC 110
Cdd:pfam15430   1 CYYEENLTLKPGESYKPPG-PCERITCGADGSLTIETCGVVALPPNCKLGEY-DPTKPYPECC-PKYKC 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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