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Conserved domains on  [gi|507834142|ref|NP_001265210|]
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glycosyltransferase 8 domain-containing protein 1 [Homo sapiens]

Protein Classification

glycosyltransferase family protein( domain architecture ID 10157674)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT8_like_1 cd06429
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of ...
 66-351 3.23e-112

GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.


:

Pssm-ID: 133051 [Multi-domain]  Cd Length: 257  Bit Score: 327.81  E-value: 3.23e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  66 IPVVIAASEdRLGGAIAAINSIQHNTR-SNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPD-- 142
Cdd:cd06429    1 IHVVIFSDN-RLAAAVVINSSISNNKDpSNLVFHIVTDNQNYGAMRSWFDLNPLKIATVKVLNFDDFKLLGKVKVDSLmq 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 143 -------------QGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEdcdsastkvvi 209
Cdd:cd06429   80 leseadtsnlkqrKPEYISLLNFARFYLPELFPKLEKVIYLDDDVVVQKDLTELWNTDLGGGVAGAVET----------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 210 rgagnqynyigyldykkerirklsmkastcSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGlysRTLAGSITTPPLL 289
Cdd:cd06429  149 ------------------------------SWNPGVNVVNLTEWRRQNVTETYEKWMELNQEEE---VTLWKLITLPPGL 195

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 507834142 290 IVFYQQHSTIDPMWNVRHLGSSAGKRysPQFVKAAKLLHWNGHLKPWGRTA--SYTDVWEKWYI 351
Cdd:cd06429  196 IVFYGLTSPLDPSWHVRGLGYNYGIR--PQDIKAAAVLHFNGNMKPWLRTAipSYKELWEKYLS 257
 
Name Accession Description Interval E-value
GT8_like_1 cd06429
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of ...
 66-351 3.23e-112

GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.


Pssm-ID: 133051 [Multi-domain]  Cd Length: 257  Bit Score: 327.81  E-value: 3.23e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  66 IPVVIAASEdRLGGAIAAINSIQHNTR-SNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPD-- 142
Cdd:cd06429    1 IHVVIFSDN-RLAAAVVINSSISNNKDpSNLVFHIVTDNQNYGAMRSWFDLNPLKIATVKVLNFDDFKLLGKVKVDSLmq 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 143 -------------QGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEdcdsastkvvi 209
Cdd:cd06429   80 leseadtsnlkqrKPEYISLLNFARFYLPELFPKLEKVIYLDDDVVVQKDLTELWNTDLGGGVAGAVET----------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 210 rgagnqynyigyldykkerirklsmkastcSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGlysRTLAGSITTPPLL 289
Cdd:cd06429  149 ------------------------------SWNPGVNVVNLTEWRRQNVTETYEKWMELNQEEE---VTLWKLITLPPGL 195

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 507834142 290 IVFYQQHSTIDPMWNVRHLGSSAGKRysPQFVKAAKLLHWNGHLKPWGRTA--SYTDVWEKWYI 351
Cdd:cd06429  196 IVFYGLTSPLDPSWHVRGLGYNYGIR--PQDIKAAAVLHFNGNMKPWLRTAipSYKELWEKYLS 257
Glyco_transf_8 pfam01501
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to ...
 67-340 4.95e-74

Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase.


Pssm-ID: 279798 [Multi-domain]  Cd Length: 252  Bit Score: 230.29  E-value: 4.95e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142   67 PVVIAASEDRLGGAIAAINSI-QHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGE 145
Cdd:pfam01501   1 CIALALDKNYLLGASVSIKSLlKNNSDFALNFHIFTDDIPVENLDILNWLASSYKPVLPLLESDIKIFEYFSKLKLRSPK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  146 SMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDcdsastkvvirgagnqyNYIGYLDYK 225
Cdd:pfam01501  81 YWSLLNYLRLYLPDLFPKLDKILYLDADIVVQGDLSPLWDIDLG-GKVLAAVED-----------------NYFQRYPNF 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  226 KERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVeeglySRTLAGSITTPPLLIVFYQQHSTIDPMWNV 305
Cdd:pfam01501 143 SEPIILENFGPPACYFNAGMLLFDLDAWRKENITERYIKWLNLNE-----NRTLWKLGDQDPLNIVFYGKVKPLDPRWNV 217

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 507834142  306 RHLGSSAGKRYSPQFVKAAKLLHWNGHLKPWGRTA 340
Cdd:pfam01501 218 LGLGYYNKKKSLNEITENAAVIHYNGPTKPWLDIA 252
RfaJ COG1442
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ...
 63-350 2.77e-23

Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441051 [Multi-domain]  Cd Length: 301  Bit Score: 98.12  E-value: 2.77e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  63 QEEIPVVIAASEDRLGGAIAAINSI-QHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEgkvkeDP 141
Cdd:COG1442    3 KNTINIVFAIDDNYLPGLGVSIASLlENNPDRPYDFHILTDGLSDENKERLEALAAKYNVSIEFIDVDDELLK-----DL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 142 DQGESMKPLTFARFYLPILVPSA-KKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSAStkvvirgagnqynyig 220
Cdd:COG1442   78 PVSKHISKATYYRLLIPELLPDDyDKVLYLDADTLVLGDLSELWDIDLG-GNLLAAVRDGTVTG---------------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 221 yldYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYsrtlagsittpP----LLIVFYQQH 296
Cdd:COG1442  141 ---SQKKRAKRLGLPDDDGYFNSGVLLINLKKWREENITEKALEFLKENPDKLKY-----------PdqdiLNIVLGGKV 206

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 507834142 297 STIDPMWNV-----RHLGSSAGKRYSPQFVKAAKLLHWNGHLKPW--GRTASYTDVWEKWY 350
Cdd:COG1442  207 KFLPPRYNYqyslyYELKDKSNKKELLEARKNPVIIHYTGPTKPWhkWCTHPYADLYWEYL 267
PLN02742 PLN02742
Probable galacturonosyltransferase
 154-349 5.80e-22

Probable galacturonosyltransferase


Pssm-ID: 215395 [Multi-domain]  Cd Length: 534  Bit Score: 97.15  E-value: 5.80e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 154 RFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSAStkvvirgagnqYNYIGYLDYKKERIRKlS 233
Cdd:PLN02742 343 RFYIPEIYPALEKVVFLDDDVVVQKDLTPLFSIDLH-GNVNGAVETCLETF-----------HRYHKYLNFSHPLISS-H 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 234 MKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEeglysRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAg 313
Cdd:PLN02742 410 FDPDACGWAFGMNVFDLVAWRKANVTAIYHYWQEQNVD-----RTLWKLGTLPPGLLTFYGLTEPLDRRWHVLGLGYDT- 483

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 507834142 314 kRYSPQFVKAAKLLHWNGHLKPWGRTA--SYTDVWEKW 349
Cdd:PLN02742 484 -NIDPRLIESAAVLHFNGNMKPWLKLAieRYKPLWERY 520
 
Name Accession Description Interval E-value
GT8_like_1 cd06429
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of ...
 66-351 3.23e-112

GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.


Pssm-ID: 133051 [Multi-domain]  Cd Length: 257  Bit Score: 327.81  E-value: 3.23e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  66 IPVVIAASEdRLGGAIAAINSIQHNTR-SNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPD-- 142
Cdd:cd06429    1 IHVVIFSDN-RLAAAVVINSSISNNKDpSNLVFHIVTDNQNYGAMRSWFDLNPLKIATVKVLNFDDFKLLGKVKVDSLmq 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 143 -------------QGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEdcdsastkvvi 209
Cdd:cd06429   80 leseadtsnlkqrKPEYISLLNFARFYLPELFPKLEKVIYLDDDVVVQKDLTELWNTDLGGGVAGAVET----------- 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 210 rgagnqynyigyldykkerirklsmkastcSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGlysRTLAGSITTPPLL 289
Cdd:cd06429  149 ------------------------------SWNPGVNVVNLTEWRRQNVTETYEKWMELNQEEE---VTLWKLITLPPGL 195

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 507834142 290 IVFYQQHSTIDPMWNVRHLGSSAGKRysPQFVKAAKLLHWNGHLKPWGRTA--SYTDVWEKWYI 351
Cdd:cd06429  196 IVFYGLTSPLDPSWHVRGLGYNYGIR--PQDIKAAAVLHFNGNMKPWLRTAipSYKELWEKYLS 257
Glyco_transf_8 pfam01501
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to ...
 67-340 4.95e-74

Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase.


Pssm-ID: 279798 [Multi-domain]  Cd Length: 252  Bit Score: 230.29  E-value: 4.95e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142   67 PVVIAASEDRLGGAIAAINSI-QHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGE 145
Cdd:pfam01501   1 CIALALDKNYLLGASVSIKSLlKNNSDFALNFHIFTDDIPVENLDILNWLASSYKPVLPLLESDIKIFEYFSKLKLRSPK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  146 SMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDcdsastkvvirgagnqyNYIGYLDYK 225
Cdd:pfam01501  81 YWSLLNYLRLYLPDLFPKLDKILYLDADIVVQGDLSPLWDIDLG-GKVLAAVED-----------------NYFQRYPNF 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  226 KERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVeeglySRTLAGSITTPPLLIVFYQQHSTIDPMWNV 305
Cdd:pfam01501 143 SEPIILENFGPPACYFNAGMLLFDLDAWRKENITERYIKWLNLNE-----NRTLWKLGDQDPLNIVFYGKVKPLDPRWNV 217

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 507834142  306 RHLGSSAGKRYSPQFVKAAKLLHWNGHLKPWGRTA 340
Cdd:pfam01501 218 LGLGYYNKKKSLNEITENAAVIHYNGPTKPWLDIA 252
Glyco_transf_8 cd00505
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis ...
 68-338 9.44e-60

Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis; Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.


Pssm-ID: 132996 [Multi-domain]  Cd Length: 246  Bit Score: 193.43  E-value: 9.44e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  68 VVIAASEDRLGGAIAAINSIQHNTRSNVIFYIVTLNntadhlRSWLNSDSLKSIRYK---IVNFDPKLLEGKVKEDPdQG 144
Cdd:cd00505    4 VIVATGDEYLRGAIVLMKSVLRHRTKPLRFHVLTNP------LSDTFKAALDNLRKLynfNYELIPVDILDSVDSEH-LK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 145 ESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEDCDSASTKVvirgagnqynyigyldy 224
Cdd:cd00505   77 RPIKIVTLTKLHLPNLVPDYDKILYVDADILVLTDIDELWDTPLGGQELAAAPDPGDRREGKY----------------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 225 kkeRIRKLSMKASTCSFNPGVFVANLTEWKR-QNITNQLEKWMKLNVeeglysrtlAGSITTPPLLIVFYQQ----HSTI 299
Cdd:cd00505  140 ---YRQKRSHLAGPDYFNSGVFVVNLSKERRnQLLKVALEKWLQSLS---------SLSGGDQDLLNTFFKQvpfiVKSL 207

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 507834142 300 DPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHLKPWGR 338
Cdd:cd00505  208 PCIWNVRLTGCYRSLNCFKAFVKNAKVIHFNGPTKPWNK 246
RfaJ COG1442
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ...
 63-350 2.77e-23

Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441051 [Multi-domain]  Cd Length: 301  Bit Score: 98.12  E-value: 2.77e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  63 QEEIPVVIAASEDRLGGAIAAINSI-QHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEgkvkeDP 141
Cdd:COG1442    3 KNTINIVFAIDDNYLPGLGVSIASLlENNPDRPYDFHILTDGLSDENKERLEALAAKYNVSIEFIDVDDELLK-----DL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 142 DQGESMKPLTFARFYLPILVPSA-KKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSAStkvvirgagnqynyig 220
Cdd:COG1442   78 PVSKHISKATYYRLLIPELLPDDyDKVLYLDADTLVLGDLSELWDIDLG-GNLLAAVRDGTVTG---------------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 221 yldYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYsrtlagsittpP----LLIVFYQQH 296
Cdd:COG1442  141 ---SQKKRAKRLGLPDDDGYFNSGVLLINLKKWREENITEKALEFLKENPDKLKY-----------PdqdiLNIVLGGKV 206

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 507834142 297 STIDPMWNV-----RHLGSSAGKRYSPQFVKAAKLLHWNGHLKPW--GRTASYTDVWEKWY 350
Cdd:COG1442  207 KFLPPRYNYqyslyYELKDKSNKKELLEARKNPVIIHYTGPTKPWhkWCTHPYADLYWEYL 267
GT8_A4GalT_like cd04194
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the ...
 66-336 4.36e-22

A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.


Pssm-ID: 133037 [Multi-domain]  Cd Length: 248  Bit Score: 93.82  E-value: 4.36e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  66 IPVVIAASEDRLGGAIAAINSI-QHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQG 144
Cdd:cd04194    1 MNIVFAIDDNYAPYLAVTIKSIlANNSKRDYDFYILNDDISEENKKKLKELLKKYNSSIEFIKIDNDDFKFFPATTDHIS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 145 ESmkplTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSASTKVVIRGAGNQYNYIGyldy 224
Cdd:cd04194   81 YA----TYYRLLIPDLLPDYDKVLYLDADIIVLGDLSELFDIDLG-DNLLAAVRDPFIEQEKKRKRRLGGYDDGSY---- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 225 kkerirklsmkastcsFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYsrtlagsittpP----LLIVFYQQHSTID 300
Cdd:cd04194  152 ----------------FNSGVLLINLKKWREENITEKLLELIKEYGGRLIY-----------PdqdiLNAVLKDKILYLP 204

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 507834142 301 PMWNV------RHLGSSAGKRYSPQFVKAAKLLHWNGHLKPW 336
Cdd:cd04194  205 PRYNFqtgfyyLLKKKSKEEQELEEARKNPVIIHYTGSDKPW 246
PLN02742 PLN02742
Probable galacturonosyltransferase
 154-349 5.80e-22

Probable galacturonosyltransferase


Pssm-ID: 215395 [Multi-domain]  Cd Length: 534  Bit Score: 97.15  E-value: 5.80e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 154 RFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSAStkvvirgagnqYNYIGYLDYKKERIRKlS 233
Cdd:PLN02742 343 RFYIPEIYPALEKVVFLDDDVVVQKDLTPLFSIDLH-GNVNGAVETCLETF-----------HRYHKYLNFSHPLISS-H 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 234 MKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEeglysRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAg 313
Cdd:PLN02742 410 FDPDACGWAFGMNVFDLVAWRKANVTAIYHYWQEQNVD-----RTLWKLGTLPPGLLTFYGLTEPLDRRWHVLGLGYDT- 483

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 507834142 314 kRYSPQFVKAAKLLHWNGHLKPWGRTA--SYTDVWEKW 349
Cdd:PLN02742 484 -NIDPRLIESAAVLHFNGNMKPWLKLAieRYKPLWERY 520
PLN02829 PLN02829
Probable galacturonosyltransferase
 150-336 7.83e-22

Probable galacturonosyltransferase


Pssm-ID: 215443 [Multi-domain]  Cd Length: 639  Bit Score: 96.84  E-value: 7.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 150 LTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSastkvvirgagNQYNYIGYLDYKKERI 229
Cdd:PLN02829 443 LNHLRFYLPEIFPKLNKVLFLDDDIVVQKDLTGLWSIDLK-GNVNGAVETCGE-----------SFHRFDRYLNFSNPLI 510

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 230 RKlSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNveeglYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLG 309
Cdd:PLN02829 511 SK-NFDPHACGWAYGMNVFDLDEWKRQNITEVYHSWQKLN-----HDRQLWKLGTLPPGLITFWKRTYPLDRSWHVLGLG 584

                        170       180       190
                 ....*....|....*....|....*....|.
gi 507834142 310 ssagkrYSPQF----VKAAKLLHWNGHLKPW 336
Cdd:PLN02829 585 ------YNPNVnqrdIERAAVIHYNGNMKPW 609
PLN02523 PLN02523
galacturonosyltransferase
 150-349 8.49e-21

galacturonosyltransferase


Pssm-ID: 215286 [Multi-domain]  Cd Length: 559  Bit Score: 93.79  E-value: 8.49e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 150 LTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCdsastkvvirgAGNQYNYIGYLDYKKERI 229
Cdd:PLN02523 363 LNHLRFYLPEMYPKLHRILFLDDDVVVQKDLTGLWKIDMD-GKVNGAVETC-----------FGSFHRYAQYLNFSHPLI 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 230 R-KLSMKAstCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEeglysRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHL 308
Cdd:PLN02523 431 KeKFNPKA--CAWAYGMNIFDLDAWRREKCTEQYHYWQNLNEN-----RTLWKLGTLPPGLITFYSTTKPLDKSWHVLGL 503

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 507834142 309 GssagkrYSPQF----VKAAKLLHWNGHLKPWGRTA--SYTDVWEKW 349
Cdd:PLN02523 504 G------YNPSIsmdeIRNAAVIHFNGNMKPWLDIAmnQFKPLWTKY 544
PLN02910 PLN02910
polygalacturonate 4-alpha-galacturonosyltransferase
 150-353 1.24e-20

polygalacturonate 4-alpha-galacturonosyltransferase


Pssm-ID: 215493 [Multi-domain]  Cd Length: 657  Bit Score: 93.47  E-value: 1.24e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 150 LTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSAStkvvirgagnqYNYIGYLDYKKERI 229
Cdd:PLN02910 461 LNHLRFYLPEVYPKLEKILFLDDDIVVQKDLTPLWSIDMQ-GMVNGAVETCKESF-----------HRFDKYLNFSNPKI 528

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 230 RKlSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEeglysRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLG 309
Cdd:PLN02910 529 SE-NFDPNACGWAFGMNMFDLKEWRKRNITGIYHYWQDLNED-----RTLWKLGSLPPGLITFYNLTYPLDRSWHVLGLG 602

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 507834142 310 ssagkrYSPQF----VKAAKLLHWNGHLKPWGRTA--SYTDVWEKWYIPD 353
Cdd:PLN02910 603 ------YDPALnqteIENAAVVHYNGNYKPWLDLAiaKYKPYWSRYVQYD 646
PLN02659 PLN02659
Probable galacturonosyltransferase
 70-336 1.37e-20

Probable galacturonosyltransferase


Pssm-ID: 215356 [Multi-domain]  Cd Length: 534  Bit Score: 93.17  E-value: 1.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  70 IAASEDRLGGAIAAINSIQHNTRSN-VIFYIVTLNNTADHLRSWLNSDSLKS--IRYKIVNFDPKLLEGKV----KEDPD 142
Cdd:PLN02659 211 VLASDNILAASVVANSLVQNALRPHkFVLHIITDRKTYSPMQAWFSLHPLSPaiIEVKALHHFDWFAKGKVpvleAMEKD 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 143 Q--------GESM-------KPLTFA-----------------RFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKp 190
Cdd:PLN02659 291 QrvrsqfrgGSSAivannteKPHVIAaklqalspkynsvmnhiRIHLPELFPSLNKVVFLDDDIVVQTDLSPLWDIDMN- 369

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 191 GHAAAFSEDCDSASTKVVIRGAGNqynyigYLDYKKERIRKlSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNV 270
Cdd:PLN02659 370 GKVNGAVETCRGEDKFVMSKKLKS------YLNFSHPLIAK-NFDPNECAWAYGMNIFDLEAWRKTNISSTYHHWLEENL 442

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 507834142 271 EEGLYSRTLAgsiTTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPqfVKAAKLLHWNGHLKPW 336
Cdd:PLN02659 443 KSDLSLWQLG---TLPPGLIAFHGHVHVIDPFWHMLGLGYQENTSLAD--AESAGVVHFNGRAKPW 503
PLN02870 PLN02870
Probable galacturonosyltransferase
 70-336 1.86e-20

Probable galacturonosyltransferase


Pssm-ID: 215468 [Multi-domain]  Cd Length: 533  Bit Score: 92.69  E-value: 1.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  70 IAASEDRLGGAIAAINSIQHNTR-SNVIFYIVTLNNTADHLRSW--LNSDSLKSIRYKIVN-FD---------------- 129
Cdd:PLN02870 210 VLSTDNILAASVVVSSTVQSSLKpEKIVFHVITDKKTYAGMHSWfaLNSVSPAIVEVKGVHqFDwltrenvpvleavesh 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 130 ---------------------PKLLEGKVKEDPDQGESMkpLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTAL 188
Cdd:PLN02870 290 ngirnyyhgnhiaganlsettPRTFASKLQARSPKYISL--LNHLRIYLPELFPNLDKVVFLDDDVVIQRDLSPLWDIDL 367

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 189 KpGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKkerirklSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKL 268
Cdd:PLN02870 368 G-GKVNGAVETCRGEDEWVMSKRFRNYFNFSHPLIAK-------NLDPEECAWAYGMNIFDLRAWRKTNIRETYHSWLKE 439

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 507834142 269 NVEEGLysrTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSagKRYSPQFVKAAKLLHWNGHLKPW 336
Cdd:PLN02870 440 NLKSNL---TMWKLGTLPPALIAFKGHVHPIDPSWHMLGLGYQ--SKTNIESVKKAAVIHYNGQSKPW 502
PLN02867 PLN02867
Probable galacturonosyltransferase
 69-336 9.97e-19

Probable galacturonosyltransferase


Pssm-ID: 178458 [Multi-domain]  Cd Length: 535  Bit Score: 87.65  E-value: 9.97e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  69 VIAASEDRLGGAIAAINSIQHNTR-SNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKI-----------VNFDPK-LLE- 134
Cdd:PLN02867 214 VVLLTDNVLAASVVISSTVQNAANpEKLVFHIVTDKKTYTPMHAWFAINSIKSAVVEVkglhqydwsqeVNVGVKeMLEi 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 135 ---------GKVKEDPDQGE--------SMKP-----LTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTAL-KPG 191
Cdd:PLN02867 294 hrliwshyyQNLKESDFQFEgthkrsleALSPsclslLNHLRIYIPELFPDLNKIVFLDDDVVVQHDLSSLWELDLnGKV 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 192 HAAAFSEDCDSASTkvvirgAGNQYNyiGYLDYKKERIRKlSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVE 271
Cdd:PLN02867 374 VGAVVDSWCGDNCC------PGRKYK--DYLNFSHPLISS-NLDQERCAWLYGMNVFDLKAWRRTNITEAYHKWLKLSLN 444

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 507834142 272 EGLysrTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKrYSPQFVKAAKLLHWNGHLKPW 336
Cdd:PLN02867 445 SGL---QLWQPGALPPALLAFKGHVHPIDPSWHVAGLGSRPPE-VPREILESAAVLHFSGPAKPW 505
PLN02718 PLN02718
Probable galacturonosyltransferase
 95-336 5.38e-17

Probable galacturonosyltransferase


Pssm-ID: 178320 [Multi-domain]  Cd Length: 603  Bit Score: 82.25  E-value: 5.38e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142  95 VIFYIVT--LNNTADHLRSWLNSDSLKSIryKIVNFDP-KLLEGKVKEDPDQGESMKP-----LTFARFYLPILVPSAKK 166
Cdd:PLN02718 343 IVFHVVTdsLNYPAISMWFLLNPPGKATI--QILNIDDmNVLPADYNSLLMKQNSHDPryisaLNHARFYLPDIFPGLNK 420

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 167 AIYMDDDVIVQGDILALYNTALKpGHAAAFSEDCDSASTKVvirgaGNQYNYIGYLDykKERIRKLSMKASTCSFNPGVF 246
Cdd:PLN02718 421 IVLFDHDVVVQRDLSRLWSLDMK-GKVVGAVETCLEGEPSF-----RSMDTFINFSD--PWVAKKFDPKACTWAFGMNLF 492

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 247 vaNLTEWKRQNITNQLEKWMKLNVEEGLYSrtlAGSIttPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPqfVKAAKL 326
Cdd:PLN02718 493 --DLEEWRRQKLTSVYHKYLQLGVKRPLWK---AGSL--PIGWLTFYNQTVALDKRWHVLGLGHESGVGASD--IEQAAV 563

                        250
                 ....*....|
gi 507834142 327 LHWNGHLKPW 336
Cdd:PLN02718 564 IHYDGVMKPW 573
PLN02769 PLN02769
Probable galacturonosyltransferase
 155-336 5.08e-11

Probable galacturonosyltransferase


Pssm-ID: 215412 [Multi-domain]  Cd Length: 629  Bit Score: 63.95  E-value: 5.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 155 FYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKpghaaafsedcdsasTKVVirGA--------GNQYNYIGyldykk 226
Cdd:PLN02769 443 FLLPEIFKKLKKVVVLDDDVVVQRDLSFLWNLDMG---------------GKVN--GAvqfcgvrlGQLKNYLG------ 499

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 507834142 227 erirKLSMKASTCSFNPGVFVANLTEWKRQNITN---QLEKWMKLNVEEGLYSRTLAGSittpplLIVFYQQHSTIDPMW 303
Cdd:PLN02769 500 ----DTNFDTNSCAWMSGLNVIDLDKWRELDVTEtylKLLQKFSKDGEESLRAAALPAS------LLTFQDLIYPLDDRW 569

                        170       180       190
                 ....*....|....*....|....*....|...
gi 507834142 304 NVRHLGSSAGkrYSPQFVKAAKLLHWNGHLKPW 336
Cdd:PLN02769 570 VLSGLGHDYG--IDEQAIKKAAVLHYNGNMKPW 600
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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