NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|429535846|ref|NP_001258835|]
View 

GSK3B-interacting protein [Homo sapiens]

Protein Classification

GSK3-beta interaction protein( domain architecture ID 10526340)

GSK3-beta interaction protein (GSKIP) is a DUF727 domain-containing protein which acts as a kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GSKIP_dom pfam05303
GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to ...
 33-133 1.10e-47

GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to GSK3beta. It is also found as a short domain towards the N terminus in clustered mitochondria protein, also known as clueless in Drosophila, which is involved in proper cytoplasmic distribution of mitochondria.


:

Pssm-ID: 398795  Cd Length: 103  Bit Score: 148.88  E-value: 1.10e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535846   33 MRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLELTEAGLKVVGYAFDQVDDH--LQTPYHETVYSL 110
Cdd:pfam05303   1 FRLEAEAAVNDVAFGVKDISVSEKLPSTNGVAYINVTTLEGNRYCIELSAAGFRIVGYRYDCVDGEseDHTKYYETLYAL 80

                          90       100
                  ....*....|....*....|...
gi 429535846  111 LDTLSPAYREAFGNALLQRLEAL 133
Cdd:pfam05303  81 LDYISPLYRESFGEALLEKLSKL 103
 
Name Accession Description Interval E-value
GSKIP_dom pfam05303
GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to ...
 33-133 1.10e-47

GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to GSK3beta. It is also found as a short domain towards the N terminus in clustered mitochondria protein, also known as clueless in Drosophila, which is involved in proper cytoplasmic distribution of mitochondria.


Pssm-ID: 398795  Cd Length: 103  Bit Score: 148.88  E-value: 1.10e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535846   33 MRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLELTEAGLKVVGYAFDQVDDH--LQTPYHETVYSL 110
Cdd:pfam05303   1 FRLEAEAAVNDVAFGVKDISVSEKLPSTNGVAYINVTTLEGNRYCIELSAAGFRIVGYRYDCVDGEseDHTKYYETLYAL 80

                          90       100
                  ....*....|....*....|...
gi 429535846  111 LDTLSPAYREAFGNALLQRLEAL 133
Cdd:pfam05303  81 LDYISPLYRESFGEALLEKLSKL 103
 
Name Accession Description Interval E-value
GSKIP_dom pfam05303
GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to ...
 33-133 1.10e-47

GSKIP domain; This domain is found in GSK3-beta interaction protein (GSKIP), which binds to GSK3beta. It is also found as a short domain towards the N terminus in clustered mitochondria protein, also known as clueless in Drosophila, which is involved in proper cytoplasmic distribution of mitochondria.


Pssm-ID: 398795  Cd Length: 103  Bit Score: 148.88  E-value: 1.10e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 429535846   33 MRLEAEAVVNDVLFAVNNMFVSKSLRCADDVAYINVETKERNRYCLELTEAGLKVVGYAFDQVDDH--LQTPYHETVYSL 110
Cdd:pfam05303   1 FRLEAEAAVNDVAFGVKDISVSEKLPSTNGVAYINVTTLEGNRYCIELSAAGFRIVGYRYDCVDGEseDHTKYYETLYAL 80

                          90       100
                  ....*....|....*....|...
gi 429535846  111 LDTLSPAYREAFGNALLQRLEAL 133
Cdd:pfam05303  81 LDYISPLYRESFGEALLEKLSKL 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH