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Conserved domains on  [gi|388423198|ref|NP_001253965|]
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large neutral amino acids transporter small subunit 2 isoform c [Homo sapiens]

Protein Classification

amino acid permease( domain architecture ID 1000062)

amino acid permease facilitates the transport of amino acids, similar to solute carrier family 7 (SLC7) members

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
2A0308 super family cl30119
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 65-392 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


The actual alignment was detected with superfamily member TIGR00911:

Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 527.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFqEPDIGLVALAFLQGSFAYGGWN 144
Cdd:TIGR00911 174 LLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVESLNPKNAFEGT-ETSAGGIVLAFYSGIWAYGGWN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  145 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGG 224
Cdd:TIGR00911 253 YLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGS 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  225 VNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVL 304
Cdd:TIGR00911 333 VNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWL 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  305 RWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQK 384
Cdd:TIGR00911 413 RYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQK 492


                  ....*...
gi 388423198  385 MCVVVYPE 392
Cdd:TIGR00911 493 VLEVVKPQ 500
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 65-392 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 527.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFqEPDIGLVALAFLQGSFAYGGWN 144
Cdd:TIGR00911 174 LLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVESLNPKNAFEGT-ETSAGGIVLAFYSGIWAYGGWN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  145 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGG 224
Cdd:TIGR00911 253 YLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGS 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  225 VNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVL 304
Cdd:TIGR00911 333 VNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWL 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  305 RWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQK 384
Cdd:TIGR00911 413 RYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQK 492


                  ....*...
gi 388423198  385 MCVVVYPE 392
Cdd:TIGR00911 493 VLEVVKPQ 500
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
65-360 2.30e-57

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 194.73  E-value: 2.30e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNafenfqePDIGLVALAFLQGSFAYGGWN 144
Cdd:COG0531  134 LLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVVGLFAFDPANFTPFLPAG-------GGLSGVLAALALAFFAFTGFE 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 145 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLG-VMAWIMPISVALSTFG 223
Cdd:COG0531  207 AIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGpWGAILIALGALLSLLG 286

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 224 GVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTC-ISTLLMLVTSDMYT-LINYVGFINYLFYGVTVAGQ 301
Cdd:COG0531  287 ALNASILGASRLLYAMARDGLLPKVFAKVHPRFGTPVNAILLTGvIALLLLLLGAASFTaLASLASVGVLLAYLLVALAV 366

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 302 IVLRWKKPDIPRPIKINL-LFPIIYLLFWAFLLVFSLWSEPVvcgIGLAIMLTGVPVYFL 360
Cdd:COG0531  367 IVLRRRRPDLPRPFRVPLpLIPILGILLCLFLLYLLGPGALL---IGLVLLAIGLLLYLL 423
AA_permease_2 pfam13520
Amino acid permease;
65-335 3.14e-32

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 126.66  E-value: 3.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDI-FTAGKLLALALIIIMGIVQICKGEYFwlEPKNAFENFQEPDIGLVALAFLQGSFAYGGW 143
Cdd:pfam13520 127 IIFAIINIRGVRESAKIQNIlGILKLLLPLILIIILGLVTADGGGFN--LLSGEWHTFFPDGWPGVFAGFLGVLWSFTGF 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  144 NFLNYVTEElvDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMsPQELLASNAVAVTFGEKLL-----GVMAWIMPISVA 218
Cdd:pfam13520 205 ESAANVSEE--VKKRNVPKAIFIGVIIVGVLYILVNIAFFGVV-PDDEIALSSGLGQVAALLFqavggKWGAIIVVILLA 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  219 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV-KRCTPIPALLFTCISTLLM-----LVTSDMYTLINYVGFINYL 292
Cdd:pfam13520 282 LSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVnKFGSPIRAIILTAILSLILlllflLSPAAYNALLSLSAYGYLL 361

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 388423198  293 FYGVTVAGQIVLRWKKPDIPRPIKINL--LFPIIYLLFWAFLLVF 335
Cdd:pfam13520 362 SYLLPIIGLLILRKKRPDLGRIPGRWPvaIFGILFSLFLIVALFF 406
frlA PRK11357
amino acid permease;
65-359 2.17e-13

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 71.43  E-value: 2.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIcKGEYFWLEPKNAFE---NFQEPDIGLVALaflqgSFAYG 141
Cdd:PRK11357 136 IAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWF-KAENFAAPTTTAIGatgSFMALLAGISAT-----SWSYT 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 142 GWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASN---AVAVTFGEKLLGVMAWIMPISVA 218
Cdd:PRK11357 210 GMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAM 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 219 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTV 298
Cdd:PRK11357 290 IVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTF 369

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 388423198 299 AGQIVLR--------WKKPdiPRPIKINLLFPIIYLLFWAFLlvfsLWSEPVVCGIGLAIMLTGVPVYF 359
Cdd:PRK11357 370 GSIIWCRkrddykplWRTP--AFGLMTTLAIASSLILVASTF----VWAPIPGLICAVIVIATGLPAYA 432
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 65-392 0e+00

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 527.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFqEPDIGLVALAFLQGSFAYGGWN 144
Cdd:TIGR00911 174 LLLTLVNCLSVKWATRVQDIFTACKLLALLLIIITGWVQLGKGGVESLNPKNAFEGT-ETSAGGIVLAFYSGIWAYGGWN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  145 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGG 224
Cdd:TIGR00911 253 YLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGS 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  225 VNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVL 304
Cdd:TIGR00911 333 VNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWL 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  305 RWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQK 384
Cdd:TIGR00911 413 RYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLYSPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQK 492


                  ....*...
gi 388423198  385 MCVVVYPE 392
Cdd:TIGR00911 493 VLEVVKPQ 500
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
65-360 2.30e-57

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 194.73  E-value: 2.30e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNafenfqePDIGLVALAFLQGSFAYGGWN 144
Cdd:COG0531  134 LLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVVGLFAFDPANFTPFLPAG-------GGLSGVLAALALAFFAFTGFE 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 145 FLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLG-VMAWIMPISVALSTFG 223
Cdd:COG0531  207 AIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSLALTGVVPYDELAASGAPLADAAEAVFGpWGAILIALGALLSLLG 286

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 224 GVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTC-ISTLLMLVTSDMYT-LINYVGFINYLFYGVTVAGQ 301
Cdd:COG0531  287 ALNASILGASRLLYAMARDGLLPKVFAKVHPRFGTPVNAILLTGvIALLLLLLGAASFTaLASLASVGVLLAYLLVALAV 366

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 302 IVLRWKKPDIPRPIKINL-LFPIIYLLFWAFLLVFSLWSEPVvcgIGLAIMLTGVPVYFL 360
Cdd:COG0531  367 IVLRRRRPDLPRPFRVPLpLIPILGILLCLFLLYLLGPGALL---IGLVLLAIGLLLYLL 423
AA_permease_2 pfam13520
Amino acid permease;
65-335 3.14e-32

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 126.66  E-value: 3.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDI-FTAGKLLALALIIIMGIVQICKGEYFwlEPKNAFENFQEPDIGLVALAFLQGSFAYGGW 143
Cdd:pfam13520 127 IIFAIINIRGVRESAKIQNIlGILKLLLPLILIIILGLVTADGGGFN--LLSGEWHTFFPDGWPGVFAGFLGVLWSFTGF 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  144 NFLNYVTEElvDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMsPQELLASNAVAVTFGEKLL-----GVMAWIMPISVA 218
Cdd:pfam13520 205 ESAANVSEE--VKKRNVPKAIFIGVIIVGVLYILVNIAFFGVV-PDDEIALSSGLGQVAALLFqavggKWGAIIVVILLA 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  219 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHV-KRCTPIPALLFTCISTLLM-----LVTSDMYTLINYVGFINYL 292
Cdd:pfam13520 282 LSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVnKFGSPIRAIILTAILSLILlllflLSPAAYNALLSLSAYGYLL 361

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 388423198  293 FYGVTVAGQIVLRWKKPDIPRPIKINL--LFPIIYLLFWAFLLVF 335
Cdd:pfam13520 362 SYLLPIIGLLILRKKRPDLGRIPGRWPvaIFGILFSLFLIVALFF 406
AA_permease pfam00324
Amino acid permease;
65-337 2.45e-22

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 98.93  E-value: 2.45e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIC-----KGEYFWLEPKNAFENFQEPDIGL-VALAFLQGSF 138
Cdd:pfam00324 122 VLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIILLSggnpnDGAIFRYLGDNGGKNNFPPGFGKgFISVFVIAFF 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  139 AYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFG-----EKLLGVMAW-- 211
Cdd:pfam00324 202 AFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAASpfvifFKFLGISGLap 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  212 IMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAmIHVKRCTPIPALLFTCISTLLMLVTSDMYT------LINY 285
Cdd:pfam00324 282 LINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK-KVDKRGVPLRAILVSMVISLLALLLASLNPaivfnfLLAI 360

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 388423198  286 VGFINYLFYGVTVAGQIvlRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSL 337
Cdd:pfam00324 361 SGLSGLIVWGLISLSHL--RFRKAFKYQGRSIDELPFKAPLGPLGVILGLAA 410
frlA PRK11357
amino acid permease;
65-359 2.17e-13

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 71.43  E-value: 2.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIcKGEYFWLEPKNAFE---NFQEPDIGLVALaflqgSFAYG 141
Cdd:PRK11357 136 IAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWF-KAENFAAPTTTAIGatgSFMALLAGISAT-----SWSYT 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 142 GWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASN---AVAVTFGEKLLGVMAWIMPISVA 218
Cdd:PRK11357 210 GMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAM 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 219 LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTV 298
Cdd:PRK11357 290 IVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTF 369

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 388423198 299 AGQIVLR--------WKKPdiPRPIKINLLFPIIYLLFWAFLlvfsLWSEPVVCGIGLAIMLTGVPVYF 359
Cdd:PRK11357 370 GSIIWCRkrddykplWRTP--AFGLMTTLAIASSLILVASTF----VWAPIPGLICAVIVIATGLPAYA 432
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 75-307 2.49e-11

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 65.61  E-value: 2.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   75 VRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALA---FlqgsFAYGGWNFLNYVTE 151
Cdd:TIGR00906 180 VKESAWVNKIFTAINILVLLFVIIAGFTKADVANWSITEEKGAGGFMPYGFTGVLSGAatcF----FAFIGFDAIATTGE 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  152 ELVDPYKNLPRAIFISIpLVTFVYVFANVAYVTAMSPQELLASNA-VAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLF 230
Cdd:TIGR00906 256 EVKNPQRAIPIGIVTSL-LVCFVAYFLMSAALTLMMPYYLLDPDApFPVAFEYVGWDPAKYIVAVGALCGMSTSLLGGMF 334

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 388423198  231 TSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWK 307
Cdd:TIGR00906 335 PLPRVIYAMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAYSLVAACVLILRYQ 411
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
65-360 9.47e-11

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 63.22  E-value: 9.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPD------IGLVALAFLQGSF 138
Cdd:COG1113  138 VLLTAINLLSVKLFGEFEFWFALIKVVAIVAFIVVGLLLIFFGFGLPGGPPAGLSNLWDHGgffpngIGGVLAALQIVVF 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 139 AYGGwnflnyvTE-------ELVDPYKNLPRAIfISIPL-VTFVYVFAnVAYVTAMSP-QELLASNAVAVTFGEKL-LGV 208
Cdd:COG1113  218 AFGG-------IElvgiaaaEAKDPEKTIPKAI-NSVIWrILLFYVGS-LFVILALVPwNQIGAGGSPFVTVFSLLgIPA 288

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 209 MAWIMPISV---ALSTFggvNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCISTLL-----MLVTSDMY 280
Cdd:COG1113  289 AAGIMNFVVltaALSSL---NSGLYSTSRMLYSLAERGDAPKFFGKLS-KRGVPVRAILLSAVVLLIgvvlnYLLPEKAF 364

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 281 TLI-NYVGFINYLFYGVTVAGQIVLR-WKKPDIPRPIKINL-LFP---IIYLLFWAFLLVFSLWSE----PVVCGIGLAI 350
Cdd:COG1113  365 TFLlSISGFGALFVWLMILVSQLKFRrRLPREGAAALKFKMpGFPytsYLTLAFLAAVLVLMAFDPdtriALIVGPVWLA 444

                        330
                 ....*....|
gi 388423198 351 MLTGvpVYFL 360
Cdd:COG1113  445 LLVV--GYFL 452
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 84-278 5.66e-10

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 61.15  E-value: 5.66e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   84 IFTAGKLLALALIIIMGIVQICKG----EYF----WLEPKnAFENFQEPDIGL-VALAFLQGSFAYGGWNFLNYVTEELV 154
Cdd:TIGR00913 146 WFSSIKILAIIGFIILSIILNCGGgpnhGYIgfryWHDPG-AFAGGTIGGRFKgVCSVFVTAAFSFGGTELVALTAGEAA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  155 DPYKNLPRAIFISIPLVTFVYVFANVAY---VTAMSPQELLASNAVAV----------TFGEKllgVMAWIMPISVALST 221
Cdd:TIGR00913 225 NPRKSIPRAAKRTFWRILVFYILTLFLIgflVPYNDPRLLSSSSSSDSaaspfviaiqNHGIK---VLPHIFNAVILISV 301

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 388423198  222 FGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCISTLL-MLVTSD 278
Cdd:TIGR00913 302 LSAANSSLYASSRTLYALAHQGLAPKIFAYVD-RRGVPYVAVIVSSLFGLLaFLAVSK 358
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 138-334 7.19e-08

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 54.35  E-value: 7.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 138 FAYGGWNFLNYVTEELVDPYKNLPRAI-FISIPLVTFvYVFANVAYVTAMSPQELLASNAVAVT-FGEKLLGVMAWIMPI 215
Cdd:PRK11049 222 FAFVGIELVGTTAAETKDPEKSLPRAInSIPIRIIMF-YVFALIVIMSVTPWSSVVPDKSPFVElFVLVGLPAAASVINF 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 216 SVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCI----STLLMLVTSDM---YTLINYVGF 288
Cdd:PRK11049 301 VVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKLS-KRAVPAKGLTFSCIcllgGVVLLYVNPSVigaFTLVTTVSA 379

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 388423198 289 INYLF-YGVTVAGQIVLRWKKPDIPRPIKINLLFPIIY----LLFWAFLLV 334
Cdd:PRK11049 380 ILFMFvWTIILCSYLVYRKQRPHLHEKSIYKMPLGKLMcwvcMAFFAFVLV 430
proY PRK10580
putative proline-specific permease; Provisional
 138-272 3.30e-05

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 45.97  E-value: 3.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 138 FAYGGWNFLNYVTEELVDPYKNLPRAIFiSIPLVTFVYVFANVAYVTAMSPQELLASNA--VAVTFGEKLLGVMAWIMPI 215
Cdd:PRK10580 210 FAYGGIEIIGITAGEAKDPEKSIPRAIN-SVPMRILVFYVGTLFVIMSIYPWNQVGTNGspFVLTFQHMGITFAASILNF 288

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 388423198 216 SVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCISTLL 272
Cdd:PRK10580 289 VVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTS-RRGIPWVTVLVMTTALLF 344
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 70-273 3.30e-05

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 45.89  E-value: 3.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198   70 VNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICkGEYFwlEPKNAFENFQ------EPDIGLVALAFLQGSFAYGGW 143
Cdd:TIGR00907 157 INSLPTKWLPRITSSAAYWSLLGFLTICITLLACKS-PKFN--DGKFVFTNFNnstggwKPGGFAFLLGLLNPAWSMTGY 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  144 NFLNYVTEELVDPYKNLPRAIFISIPL-VTFVYVFANVAYVTAMSPQELLASNA---VAVTFGEKL---LGVMAWIMPIS 216
Cdd:TIGR00907 234 DGTAHMAEEIENPEVVGPRAIIGAVAIgIVTGFCFNIVLFFSMGDIDSLISSTTgqpIAQIFYNALgnkAGAIFLLCLIL 313

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 388423198  217 VAlsTFGGVNGSLFTSSRLFFAGAREGHLP--SVLAMIHVKRCTPIPALLFTCISTLLM 273
Cdd:TIGR00907 314 VT--SFFCAITCMTANSRMIYAFSRDGGLPfsPLWSRVNPRTQVPLNAVWLSAVWIILI 370
PRK10238 PRK10238
aromatic amino acid transporter AroP;
138-369 7.92e-05

aromatic amino acid transporter AroP;


Pssm-ID: 182324 [Multi-domain]  Cd Length: 456  Bit Score: 44.95  E-value: 7.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 138 FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAV----TFGEKLLGVMAWIM 213
Cdd:PRK10238 211 FSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVlifhELGDTFVANALNIV 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 214 PISVALSTFggvNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCISTLLMLvtsdmytLINYVG------ 287
Cdd:PRK10238 291 VLTAALSVY---NSCVYCNSRMLFGLAQQGNAPKALASVD-KRGVPVNTILVSALVTALCV-------LINYLApesafg 359

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 288 ----------FINYLFygVTVAGQIVLRWKKPDIPRPIKINLLFPI---IYLLFWAFLLVFSLWSEpvvcGIGLAIMLTG 354
Cdd:PRK10238 360 llmalvvsalVINWAM--ISLAHMKFRRAKQEQGVVTRFPALLYPLgnwICLLFMAAVLVIMLMTP----GMAISVYLIP 433

                        250
                 ....*....|....*
gi 388423198 355 VPVYFLGVYWQHKPK 369
Cdd:PRK10238 434 VWLIVLGIGYLFKEK 448
PRK11021 PRK11021
putative transporter; Provisional
 65-275 3.31e-04

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 42.59  E-value: 3.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  65 LLLTWVNCSSVRWATRVQDIFTagkLLALALI-IIMGIVQICKGEYFWLEPknafenfQEPDIGLVALAFlqgsfAYGGW 143
Cdd:PRK11021 124 ALLWLLNLRGASSSANLQTVIA---LLIVALVvAIWWAGDIKPADIPFPAP-------GSIEWSGLFAAL-----GVMFW 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 144 NFLN-----YVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMA-WIMPISV 217
Cdd:PRK11021 189 CFVGieafaHLASEFKNPERDFPRALMIGLLLAGLVYWACTVVVLHFPAYGDKQAAAASLPGIFVQLFGGYAlWVICVIG 268

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 388423198 218 ALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRcTPIPALLFTCISTLLMLV 275
Cdd:PRK11021 269 YLACFASVNIYTQSFARLVWSQAREGRPPSYLARLSARG-VPVNALNAVLGCCAVSIL 325
PRK10249 PRK10249
phenylalanine transporter; Provisional
 138-286 5.55e-04

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 41.90  E-value: 5.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 138 FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVfANVAYVTAMSPQELLASNA--VAVTFGEKLLGVMAWIMPI 215
Cdd:PRK10249 220 FSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYI-GSLVVLLALYPWVEVKSNSspFVMIFHNLDSNVVASALNF 298

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 388423198 216 SVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHvKRCTPIPALLFTCISTLLMLvtsdmytLINYV 286
Cdd:PRK10249 299 VILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVS-RRGVPINSLMLSGAITSLVV-------LINYL 361
PRK15049 PRK15049
L-asparagine permease;
70-331 1.47e-03

L-asparagine permease;


Pssm-ID: 185009  Cd Length: 499  Bit Score: 40.76  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198  70 VNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGE--------YFWLEPKNAFEnfqePDIGLVALAFLQGS-FAY 140
Cdd:PRK15049 158 MNMIGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQpldgnttgFHLITDNGGFF----PHGLLPALVLIQGVvFAF 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 141 GGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKL-LGVMAWIMPISVAL 219
Cdd:PRK15049 234 ASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLgVPYIGSIMNIVVLT 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 388423198 220 STFGGVNGSLFTSSRLFFAGAREGHLPSVLAMI---HVKRCTPIPALLFTCISTLL-MLVTSDMYTLI-NYVGFINYLFY 294
Cdd:PRK15049 314 AALSSLNSGLYCTGRILRSMAMGGSAPSFMAKMsrqHVPYAGILATLVVYVVGVFLnYLVPSRVFEIVlNFASLGIIASW 393

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 388423198 295 GVTVAGQIVLR------------WKKPDIPRPIKINLLFPIIYLLFWAF 331
Cdd:PRK15049 394 AFIIVCQMRLRkaikegkaadvsFKLPGAPFTSWLTLLFLLSVLVLMAF 442
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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