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Conserved domains on  [gi|354983495|ref|NP_001238979|]
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protein-L-isoaspartate(D-aspartate) O-methyltransferase isoform 3 [Homo sapiens]

Protein Classification

protein-L-isoaspartate O-methyltransferase family protein( domain architecture ID 1000299)

protein-L-isoaspartate O-methyltransferase (PIMT) family protein catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues

Gene Ontology:  GO:0051998|GO:0036211

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCMT super family cl30237
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-239 1.81e-84

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


The actual alignment was detected with superfamily member pfam01135:

Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 250.36  E-value: 1.81e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHM------------------- 122
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMhammlellelkpgmrvlei 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  123 --------------VGCTGKVIGIDHIKELVDDSVNNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVV 188
Cdd:pfam01135  81 gsgsgyltacfarmVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAPEI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 354983495  189 PQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSIKMKPLMGVIYVPL 239
Cdd:pfam01135 156 PEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-239 1.81e-84

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 250.36  E-value: 1.81e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHM------------------- 122
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMhammlellelkpgmrvlei 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  123 --------------VGCTGKVIGIDHIKELVDDSVNNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVV 188
Cdd:pfam01135  81 gsgsgyltacfarmVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAPEI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 354983495  189 PQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSIKMKPLMGVIYVPL 239
Cdd:pfam01135 156 PEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-246 2.40e-52

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 169.24  E-value: 2.40e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMV-------------- 123
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVammtellelkpgmk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  124 ----GC---------------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAA 184
Cdd:TIGR00080  81 vleiGTgsgyqaavlaeivgrDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVTAA 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 354983495  185 APVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSIKMKPLMGVIYVPLTDKEKQW 246
Cdd:TIGR00080 156 GPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-243 2.38e-40

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 138.23  E-value: 2.38e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMVG--C------------------ 125
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAimCelldlkegmkvleigtgs 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 126 -------------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQAL 192
Cdd:PRK13942  88 gyhaavvaeivgkSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPKPL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 354983495 193 IDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSIKMKPLMGVIYVPLTDKE 243
Cdd:PRK13942 163 IEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-240 2.66e-36

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 127.13  E-value: 2.66e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMV--------------------GC- 125
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVarmlealdlkpgdrvleigtGSg 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 126 ---------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQL 196
Cdd:COG2518   79 yqaavlarlAGRVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEALLEQL 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 354983495 197 KPGGRLILPVGPaGGNQMLEQYDKLQDGsIKMKPLMGVIYVPLT 240
Cdd:COG2518  154 APGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-239 1.81e-84

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 250.36  E-value: 1.81e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHM------------------- 122
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMhammlellelkpgmrvlei 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  123 --------------VGCTGKVIGIDHIKELVDDSVNNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVV 188
Cdd:pfam01135  81 gsgsgyltacfarmVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAPEI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 354983495  189 PQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSIKMKPLMGVIYVPL 239
Cdd:pfam01135 156 PEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-246 2.40e-52

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 169.24  E-value: 2.40e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMV-------------- 123
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVammtellelkpgmk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  124 ----GC---------------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAA 184
Cdd:TIGR00080  81 vleiGTgsgyqaavlaeivgrDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVTAA 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 354983495  185 APVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSIKMKPLMGVIYVPLTDKEKQW 246
Cdd:TIGR00080 156 GPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-243 2.38e-40

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 138.23  E-value: 2.38e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMVG--C------------------ 125
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAimCelldlkegmkvleigtgs 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 126 -------------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQAL 192
Cdd:PRK13942  88 gyhaavvaeivgkSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPKPL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 354983495 193 IDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSIKMKPLMGVIYVPLTDKE 243
Cdd:PRK13942 163 IEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-240 2.66e-36

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 127.13  E-value: 2.66e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMV--------------------GC- 125
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVarmlealdlkpgdrvleigtGSg 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 126 ---------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQL 196
Cdd:COG2518   79 yqaavlarlAGRVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEALLEQL 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 354983495 197 KPGGRLILPVGPaGGNQMLEQYDKLQDGsIKMKPLMGVIYVPLT 240
Cdd:COG2518  154 APGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
71-243 4.15e-36

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 127.24  E-value: 4.15e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  71 LIHNLRKNGIiKTDKVFEVMLATDRS--------HYAkcnpYMDSPQSIGFQATISAPHMV------------------G 124
Cdd:PRK00312  12 LVLRLRAEGI-LDERVLEAIEATPRElfvpeafkHKA----YENRALPIGCGQTISQPYMVarmtellelkpgdrvleiG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 125 C------------TGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQAL 192
Cdd:PRK00312  87 TgsgyqaavlahlVRRVFSVERIKTLQWEAKRRLKQ-----LGLHNVSVRHGDGWKGWPAYAPFDRILVTAAAPEIPRAL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 354983495 193 IDQLKPGGRLILPVGpaGGNQMLEQYDKLQDGSIKMKPLMGVIYVPLTDKE 243
Cdd:PRK00312 162 LEQLKEGGILVAPVG--GEEQQLLTRVRKRGGRFEREVLEEVRFVPLVKGE 210
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 71-239 2.79e-22

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 91.03  E-value: 2.79e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  71 LIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMV----------------------- 123
Cdd:PRK13944   5 LVEELVREGIIKSERVKKAMLSVPREEFVmpeyRMMAYEDRPLPLFAGATISAPHMVammcelieprpgmkilevgtgsg 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 124 ----------GCTGKVIGIDHIKELVDDSVNNVRKddptLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALI 193
Cdd:PRK13944  85 yqaavcaeaiERRGKVYTVEIVKELAIYAAQNIER----LGYWGVVEVYHGDGKRGLEKHAPFDAIIVTAAASTIPSALV 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 354983495 194 DQLKPGGRLILPVGPAGGnQMLEQYDKLQDGsIKMKPLMGVIYVPL 239
Cdd:PRK13944 161 RQLKDGGVLVIPVEEGVG-QVLYKVVKRGEK-VEKRAITYVLFVPL 204
methyltran_FxLD TIGR04364
methyltransferase, FxLD system; Members of this family resemble occur regularly in the ...
 110-206 4.39e-12

methyltransferase, FxLD system; Members of this family resemble occur regularly in the vicinity of lantibiotic biosynthesis enzymes and their probable target, the FxLD family of putative ribosomal natural product precursor (TIGR04363). Members resemble protein-L-isoaspartate O-methyltransferase (TIGR00080) and a predicted methyltranserase, TIGR04188, of another putative peptide modification system.


Pssm-ID: 275158  Cd Length: 394  Bit Score: 65.08  E-value: 4.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495  110 SIGFQATISApHMVGCTGKVIGIDHIKELVDDSvnnvRKddptLLSS---GRVQLVVGDGRMGYAEEAPYDAIHVGAAAP 186
Cdd:TIGR04364  91 SGGYNAALLA-ELVGPSGEVTTVDIDEDVTDRA----RA----CLAAagyPQVTVVLADAEAGVPELAPYDRIIVTVGAW 161

                          90       100
                  ....*....|....*....|
gi 354983495  187 VVPQALIDQLKPGGRLILPV 206
Cdd:TIGR04364 162 DIPPAWLDQLAPGGRLVVPL 181
PRK13943 PRK13943
protein-L-isoaspartate O-methyltransferase; Provisional
 112-206 1.05e-10

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 237568 [Multi-domain]  Cd Length: 322  Bit Score: 60.63  E-value: 1.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 112 GFQATISApHMVGCTGKVIGIDHIKELVDDSVNNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQA 191
Cdd:PRK13943  92 GYNAAVMS-RVVGEKGLVVSVEYSRKICEIAKRNVRR-----LGIENVIFVCGDGYYGVPEFAPYDVIFVTVGVDEVPET 165

                         90
                 ....*....|....*
gi 354983495 192 LIDQLKPGGRLILPV 206
Cdd:PRK13943 166 WFTQLKEGGRVIVPI 180
methyltr_grsp TIGR04188
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ...
 161-211 5.03e-08

methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).


Pssm-ID: 275041  Cd Length: 363  Bit Score: 52.75  E-value: 5.03e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 354983495  161 LVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVG---PAGG 211
Cdd:TIGR04188 160 VVTGDGLLGHPPRAPYDRIIATCAVRRVPPAWLRQTRPGGVILTTLSgwlYGGG 213
PLN02366 PLN02366
spermidine synthase
 146-200 5.01e-04

spermidine synthase


Pssm-ID: 215208 [Multi-domain]  Cd Length: 308  Bit Score: 40.40  E-value: 5.01e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 354983495 146 VRKDDPtllssgRVQLVVGDGR--MGYAEEAPYDAIHVGAAAPVVP-QALIDQ---------LKPGG 200
Cdd:PLN02366 140 VGFDDP------RVNLHIGDGVefLKNAPEGTYDAIIVDSSDPVGPaQELFEKpffesvaraLRPGG 200
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 116-203 9.86e-03

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 36.29  E-value: 9.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 354983495 116 TISAPHMVGCTGKVIGIDHIKELVDDSVNNVRKddptLLSSGRVQLVVGDGRMGYAEEaPYDAIHVGAAAP--VVPQAlI 193
Cdd:COG2519  106 TLALARAVGPEGKVYSYERREDFAEIARKNLER----FGLPDNVELKLGDIREGIDEG-DVDAVFLDMPDPweALEAV-A 179

                         90
                 ....*....|
gi 354983495 194 DQLKPGGRLI 203
Cdd:COG2519  180 KALKPGGVLV 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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