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Conserved domains on  [gi|304361727|ref|NP_001181995|]
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phosphatase and actin regulator 2 isoform B [Mus musculus]

Protein Classification

RPEL repeat-containing protein( domain architecture ID 10499653)

RPEL repeat-containing protein such as Phactrs 1-4, a family of protein phosphatase 1 and actin regulatory proteins

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
438-462 9.87e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.08  E-value: 9.87e-06
                           10        20
                   ....*....|....*....|....*
gi 304361727   438 KLVRRLSQRPTTEELEQRNILKQKN 462
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
475-500 2.34e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.23  E-value: 2.34e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   475 RRLSRKLSLRPTVAELQARRILRFNE 500
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
399-424 4.52e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.46  E-value: 4.52e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   399 DTLAIKLGNRPSKKELEDKNILQRTS 424
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
62-83 5.08e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 5.08e-04
                          10        20
                  ....*....|....*....|..
gi 304361727   62 LERKISTRQSREELIRRGLLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
438-462 9.87e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.08  E-value: 9.87e-06
                           10        20
                   ....*....|....*....|....*
gi 304361727   438 KLVRRLSQRPTTEELEQRNILKQKN 462
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
438-459 9.79e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.56  E-value: 9.79e-05
                          10        20
                  ....*....|....*....|..
gi 304361727  438 KLVRRLSQRPTTEELEQRNILK 459
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
475-500 2.34e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.23  E-value: 2.34e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   475 RRLSRKLSLRPTVAELQARRILRFNE 500
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
399-424 4.52e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.46  E-value: 4.52e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   399 DTLAIKLGNRPSKKELEDKNILQRTS 424
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
62-83 5.08e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 5.08e-04
                          10        20
                  ....*....|....*....|..
gi 304361727   62 LERKISTRQSREELIRRGLLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
60-85 8.22e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.69  E-value: 8.22e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727    60 AVLERKISTRQSREELIRRGLLKELP 85
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
438-462 9.87e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.08  E-value: 9.87e-06
                           10        20
                   ....*....|....*....|....*
gi 304361727   438 KLVRRLSQRPTTEELEQRNILKQKN 462
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
438-459 9.79e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.56  E-value: 9.79e-05
                          10        20
                  ....*....|....*....|..
gi 304361727  438 KLVRRLSQRPTTEELEQRNILK 459
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILP 22
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
475-500 2.34e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 38.23  E-value: 2.34e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   475 RRLSRKLSLRPTVAELQARRILRFNE 500
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
399-424 4.52e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 37.46  E-value: 4.52e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727   399 DTLAIKLGNRPSKKELEDKNILQRTS 424
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
62-83 5.08e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 37.25  E-value: 5.08e-04
                          10        20
                  ....*....|....*....|..
gi 304361727   62 LERKISTRQSREELIRRGLLKE 83
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
60-85 8.22e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 36.69  E-value: 8.22e-04
                           10        20
                   ....*....|....*....|....*.
gi 304361727    60 AVLERKISTRQSREELIRRGLLKELP 85
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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