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Conserved domains on  [gi|156231021|ref|NP_001095881|]
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kininogen-1 isoform 1 precursor [Mus musculus]

Protein Classification

cystatin family protein( domain architecture ID 11249387)

cystatin family protein similar to cystatins which are a family of cysteine protease inhibitors

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 263-370 6.18e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.76  E-value: 6.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   263 CPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTElaEDCEIK 342
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVDL--ENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   343 HLGQsLDCNANVYMRPWENK-VVPTVKCQ 370
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 1.13e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 104.43  E-value: 1.13e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   141 CIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERfpSLHGDCVAL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   221 PNGdDGECRGNLF-MDINNKIANFSQSCT 248
Cdd:smart00043  80 DQG-EKFCTAKVWeKPWENKIKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 1.93e-15

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 72.46  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021    23 AQEIDCNDEAVFQAVDFSLKQFNPgvKSGNQYMLH--RVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLaWQDCDFKDAE 100
Cdd:smart00043   6 PSDVPPNDPEVQEAADFAVAEYNK--KSNDKYELRviKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*...
gi 156231021   101 EaatGECTATVGKR--ENEFFIVTQTCK 126
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKCT 107
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 263-370 6.18e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.76  E-value: 6.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   263 CPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTElaEDCEIK 342
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVDL--ENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   343 HLGQsLDCNANVYMRPWENK-VVPTVKCQ 370
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 3.76e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 111.41  E-value: 3.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021 265 GCPRDIPVDSPELKEVLGHSIAQLNAENDHPfYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHL 344
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231021 345 GQSLDCNANVYMRPWEN-KVVPTVKC 369
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 4.03e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 4.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  265 GCPRDIPVDSPELKEVLGHSIAQLNAENDHpFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESntELAEDCEIKHL 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSK--KLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231021  345 GQSLDCNANVYMRPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 1.13e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 104.43  E-value: 1.13e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   141 CIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERfpSLHGDCVAL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   221 PNGdDGECRGNLF-MDINNKIANFSQSCT 248
Cdd:smart00043  80 DQG-EKFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 8.43e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.17  E-value: 8.43e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021 143 GCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHlFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPN 222
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231021 223 GDDGECRGNLFMDI-NNKIANFSQSC 247
Cdd:cd00042   80 GKKKFCTAKVWEKPwENFKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-237 3.32e-21

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 88.55  E-value: 3.32e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  143 GCVHAISTDSPDLEPVLKHSIEHFNNNTdHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKerFPSLHGDCVALPN 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231021  223 GDDGECRGNLFMDIN 237
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 1.93e-15

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 72.46  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021    23 AQEIDCNDEAVFQAVDFSLKQFNPgvKSGNQYMLH--RVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLaWQDCDFKDAE 100
Cdd:smart00043   6 PSDVPPNDPEVQEAADFAVAEYNK--KSNDKYELRviKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*...
gi 156231021   101 EaatGECTATVGKR--ENEFFIVTQTCK 126
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 25-114 1.21e-14

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 69.67  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   25 EIDCNDEAVFQAVDFSLKQFNPGvKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLaWQDCDFKDaeEAAT 104
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSKKL-LEDCPLLD--EKWL 80

                          90
                  ....*....|
gi 156231021  105 GECTATVGKR 114
Cdd:pfam00031  81 GLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-125 2.89e-07

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 49.01  E-value: 2.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  24 QEIDCNDEAVFQAVDFSLKQFNPGvKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQdCDFKDAEEAA 103
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKK-SNDKYLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81

                         90       100
                 ....*....|....*....|....
gi 156231021 104 TGECTATVGKR--ENEFFIVTQTC 125
Cdd:cd00042   82 KKFCTAKVWEKpwENFKELLSFKC 105
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 263-370 6.18e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.76  E-value: 6.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   263 CPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTElaEDCEIK 342
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVDL--ENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   343 HLGQsLDCNANVYMRPWENK-VVPTVKCQ 370
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 3.76e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 111.41  E-value: 3.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021 265 GCPRDIPVDSPELKEVLGHSIAQLNAENDHPfYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHL 344
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231021 345 GQSLDCNANVYMRPWEN-KVVPTVKC 369
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 4.03e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 4.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  265 GCPRDIPVDSPELKEVLGHSIAQLNAENDHpFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESntELAEDCEIKHL 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSK--KLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231021  345 GQSLDCNANVYMRPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 1.13e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 104.43  E-value: 1.13e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   141 CIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERfpSLHGDCVAL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231021   221 PNGdDGECRGNLF-MDINNKIANFSQSCT 248
Cdd:smart00043  80 DQG-EKFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 8.43e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.17  E-value: 8.43e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021 143 GCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHlFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPN 222
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231021 223 GDDGECRGNLFMDI-NNKIANFSQSC 247
Cdd:cd00042   80 GKKKFCTAKVWEKPwENFKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-237 3.32e-21

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 88.55  E-value: 3.32e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  143 GCVHAISTDSPDLEPVLKHSIEHFNNNTdHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKerFPSLHGDCVALPN 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231021  223 GDDGECRGNLFMDIN 237
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 1.93e-15

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 72.46  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021    23 AQEIDCNDEAVFQAVDFSLKQFNPgvKSGNQYMLH--RVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLaWQDCDFKDAE 100
Cdd:smart00043   6 PSDVPPNDPEVQEAADFAVAEYNK--KSNDKYELRviKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*...
gi 156231021   101 EaatGECTATVGKR--ENEFFIVTQTCK 126
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 25-114 1.21e-14

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 69.67  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021   25 EIDCNDEAVFQAVDFSLKQFNPGvKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLaWQDCDFKDaeEAAT 104
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSKKL-LEDCPLLD--EKWL 80

                          90
                  ....*....|
gi 156231021  105 GECTATVGKR 114
Cdd:pfam00031  81 GLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-125 2.89e-07

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 49.01  E-value: 2.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231021  24 QEIDCNDEAVFQAVDFSLKQFNPGvKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQdCDFKDAEEAA 103
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKK-SNDKYLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81

                         90       100
                 ....*....|....*....|....
gi 156231021 104 TGECTATVGKR--ENEFFIVTQTC 125
Cdd:cd00042   82 KKFCTAKVWEKpwENFKELLSFKC 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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