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Conserved domains on  [gi|45827765|ref|NP_001063|]
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UDP-glucuronosyltransferase 1-6 isoform 1 precursor [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-523 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 873.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765    27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLK--ESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEY 263
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   264 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 343
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   344 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 423
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   424 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 503
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 45827765   504 ITFKCCAYGYRKCLGKKGRV 523
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-523 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 873.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765    27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLK--ESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEY 263
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   264 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 343
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   344 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 423
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   424 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 503
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 45827765   504 ITFKCCAYGYRKCLGKKGRV 523
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-445 2.09e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 246.69  E-value: 2.09e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  29 LLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLllkeskyytrkiypvPYDQEELKNRYQSFGNNHFAERSFLTAP 108
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 109 QTEYRNNMIVIGLYFINCQSLlqdRDTLNFFKES-KFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPD 187
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELL---DDLLAALRSSwKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYLHPFGV 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 188 PVSYIPrcytKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELasavLKRDVDIItlyqkVSVWllrydFVLEYPRPV 267
Cdd:cd03784 146 LNLLLS----SLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL----RLVPPLYV-----IGPT-----FPSLPPDRP 207

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 268 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NL 344
Cdd:cd03784 208 RLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRL 287

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 345 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 424
Cdd:cd03784 288 PDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAK 367

                       410       420
                ....*....|....*....|.
gi 45827765 425 ALKAVINDKSYKENIMRLSSL 445
Cdd:cd03784 368 AVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 15-506 2.23e-46

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 169.37  E-value: 2.23e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   15 VFFLALWGMVVGDKLLVV-PQDG-SHWLSMKDIVEVLSDRGHEIVVVVPevnlllKESKYYTRKIYP--------VPYDQ 84
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySHHSVFKVYVEALAERGHNVTVIKP------TLRVYYASHLCGniteidasLSVEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   85 -EELKNRYQSFGNNHF-AERSFLTApqTEYRN--NMIVIGLYFINCQSLLQdrdtlnfFKESKFDALFTDPalpcgvila 160
Cdd:PHA03392  83 fKKLVKSSAVFRKRGVvADSSTVTA--DNYMGlvRMISDQFDLPNVKNLIA-------NKNNKFDLLVTEA--------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  161 eYLGLPSVYlfrgfpcslEHTFSRSP-----------------DPVSYIPRCY-----TKFSDHMTFsQRVANFLVnllE 218
Cdd:PHA03392 145 -FLDYPLVF---------SHLFGDAPviqissgyglaenfetmGAVSRHPVYYpnlwrSKFGNLNVW-ETINEIYT---E 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  219 PYLfYCLFSKYEELASAVLKRD--VDIITLYQ-KVSVWLLrydFVLEYP-----RPVMPNMVFIGGI--NCKKRKDLSQE 288
Cdd:PHA03392 211 LRL-YNEFSLLADEQNKLLKQQfgPDTPTIRElRNRVQLL---FVNVHPvfdnnRPVPPSVQYLGGLhlHKKPPQPLDDY 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  289 FEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQTVLWRYTGT-RPSNLANNTILVKWLPQNDLLG 361
Cdd:PHA03392 287 LEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLK 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  362 HPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 441
Cdd:PHA03392 362 HKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKE 441

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45827765  442 LSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVVLTVAFITF 506
Cdd:PHA03392 442 LRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
261-443 3.10e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 124.58  E-value: 3.10e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 261 LEYPRPVMP-NMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 339
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 340 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 416
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 45827765 417 MTSEDLENALKAVINDKSYKENIMRLS 443
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 45-442 2.03e-23

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 102.07  E-value: 2.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765    45 IVEVLSDRGHEIVVVVPEvnlLLKESKYYTR---KIYPVPYDQEELKNryqsfgnnHFAERSFLTAPQTEYRNNMIVIgl 121
Cdd:TIGR01426  15 VVEELVARGHRVTYATTE---EFAERVEAAGaefVLYGSALPPPDNPP--------ENTEEEPIDIIEKLLDEAEDVL-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   122 yfincQSLLQDrdtlnfFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHtfsrsPDPVSYIPRCYTKFSD 201
Cdd:TIGR01426  82 -----PQLEEA------YKGDRPDLIVYDIASWTGRLLARKWDVPVISSFPTFAANEEF-----EEMVSPAGEGSAEEGA 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   202 HMTFSQRvanflvnllepylfyclfsKYEELASAVLKR-DVDIITLYQKVSVwllRYDFVLEY-PRPVMPN-------MV 272
Cdd:TIGR01426 146 IAERGLA-------------------EYVARLSALLEEhGITTPPVEFLAAP---RRDLNLVYtPKAFQPAgetfddsFT 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   273 FIGGINCKKRKDLSqefeAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NT 348
Cdd:TIGR01426 204 FVGPCIGDRKEDGS----WERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNV 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   349 ILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKA 428
Cdd:TIGR01426 278 EVRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLA 355

                         410
                  ....*....|....
gi 45827765   429 VINDKSYKENIMRL 442
Cdd:TIGR01426 356 VLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
27-523 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 873.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765    27 DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLK--ESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSF 104
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   105 LTaPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFS- 183
Cdd:pfam00201  81 GT-VWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSg 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   184 RSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEY 263
Cdd:pfam00201 160 GLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEF 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   264 PRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSN 343
Cdd:pfam00201 240 PRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPST 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   344 LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLE 423
Cdd:pfam00201 320 LGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLL 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   424 NALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAF 503
Cdd:pfam00201 400 NALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAF 479

                         490       500
                  ....*....|....*....|
gi 45827765   504 ITFKCCAYGYRKCLGKKGRV 523
Cdd:pfam00201 480 ITFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 29-445 2.09e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 246.69  E-value: 2.09e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  29 LLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLllkeskyytrkiypvPYDQEELKNRYQSFGNNHFAERSFLTAP 108
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPPFNF---------------ADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 109 QTEYRNNMIVIGLYFINCQSLlqdRDTLNFFKES-KFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPD 187
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELL---DDLLAALRSSwKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYLHPFGV 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 188 PVSYIPrcytKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELasavLKRDVDIItlyqkVSVWllrydFVLEYPRPV 267
Cdd:cd03784 146 LNLLLS----SLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL----RLVPPLYV-----IGPT-----FPSLPPDRP 207

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 268 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NL 344
Cdd:cd03784 208 RLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRL 287

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 345 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 424
Cdd:cd03784 288 PDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAK 367

                       410       420
                ....*....|....*....|.
gi 45827765 425 ALKAVINDKSYKENIMRLSSL 445
Cdd:cd03784 368 AVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 15-506 2.23e-46

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 169.37  E-value: 2.23e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   15 VFFLALWGMVVGDKLLVV-PQDG-SHWLSMKDIVEVLSDRGHEIVVVVPevnlllKESKYYTRKIYP--------VPYDQ 84
Cdd:PHA03392   9 LLLLLLLSGVRAARILAVfPTPAySHHSVFKVYVEALAERGHNVTVIKP------TLRVYYASHLCGniteidasLSVEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   85 -EELKNRYQSFGNNHF-AERSFLTApqTEYRN--NMIVIGLYFINCQSLLQdrdtlnfFKESKFDALFTDPalpcgvila 160
Cdd:PHA03392  83 fKKLVKSSAVFRKRGVvADSSTVTA--DNYMGlvRMISDQFDLPNVKNLIA-------NKNNKFDLLVTEA--------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  161 eYLGLPSVYlfrgfpcslEHTFSRSP-----------------DPVSYIPRCY-----TKFSDHMTFsQRVANFLVnllE 218
Cdd:PHA03392 145 -FLDYPLVF---------SHLFGDAPviqissgyglaenfetmGAVSRHPVYYpnlwrSKFGNLNVW-ETINEIYT---E 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  219 PYLfYCLFSKYEELASAVLKRD--VDIITLYQ-KVSVWLLrydFVLEYP-----RPVMPNMVFIGGI--NCKKRKDLSQE 288
Cdd:PHA03392 211 LRL-YNEFSLLADEQNKLLKQQfgPDTPTIRElRNRVQLL---FVNVHPvfdnnRPVPPSVQYLGGLhlHKKPPQPLDDY 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  289 FEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQTVLWRYTGT-RPSNLANNTILVKWLPQNDLLG 361
Cdd:PHA03392 287 LEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEvEAINLPANVLTQKWFPQRAVLK 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  362 HPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 441
Cdd:PHA03392 362 HKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKE 441

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45827765  442 LSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVVLTVAFITF 506
Cdd:PHA03392 442 LRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
261-443 3.10e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 124.58  E-value: 3.10e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 261 LEYPRPVMP-NMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 339
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 340 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 416
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 45827765 417 MTSEDLENALKAVINDKSYKENIMRLS 443
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 45-442 2.03e-23

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 102.07  E-value: 2.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765    45 IVEVLSDRGHEIVVVVPEvnlLLKESKYYTR---KIYPVPYDQEELKNryqsfgnnHFAERSFLTAPQTEYRNNMIVIgl 121
Cdd:TIGR01426  15 VVEELVARGHRVTYATTE---EFAERVEAAGaefVLYGSALPPPDNPP--------ENTEEEPIDIIEKLLDEAEDVL-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   122 yfincQSLLQDrdtlnfFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHtfsrsPDPVSYIPRCYTKFSD 201
Cdd:TIGR01426  82 -----PQLEEA------YKGDRPDLIVYDIASWTGRLLARKWDVPVISSFPTFAANEEF-----EEMVSPAGEGSAEEGA 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   202 HMTFSQRvanflvnllepylfyclfsKYEELASAVLKR-DVDIITLYQKVSVwllRYDFVLEY-PRPVMPN-------MV 272
Cdd:TIGR01426 146 IAERGLA-------------------EYVARLSALLEEhGITTPPVEFLAAP---RRDLNLVYtPKAFQPAgetfddsFT 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   273 FIGGINCKKRKDLSqefeAYINASGeHGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NT 348
Cdd:TIGR01426 204 FVGPCIGDRKEDGS----WERPGDG-RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNV 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   349 ILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKA 428
Cdd:TIGR01426 278 EVRQWVPQLEILKK--ADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLA 355

                         410
                  ....*....|....
gi 45827765   429 VINDKSYKENIMRL 442
Cdd:TIGR01426 356 VLSDPRYAERLRKM 369
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 266-434 5.59e-14

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 73.93  E-value: 5.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  266 PVMPNMVFIGGINCKK--RKDLSQEFEAYINASGEHGIVVFSLGSMVsEIPEKKAMAIADAL--GKIP------------ 329
Cdd:PLN02152 226 PLLPAEIFTGSESGKDlsVRDQSSSYTLWLDSKTESSVIYVSFGTMV-ELSKKQIEELARALieGKRPflwvitdklnre 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  330 -------QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKR 402
Cdd:PLN02152 305 akiegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKL 383

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 45827765  403 ME---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 434
Cdd:PLN02152 384 LEeiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 292-404 1.65e-12

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 69.30  E-value: 1.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  292 YINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKIPQTVLWRytgTRPSNLANNT-----------------ILVKW 353
Cdd:PLN02410 257 WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGSVRGSEwieslpkefskiisgrgYIVKW 331

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 45827765  354 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 404
Cdd:PLN02410 332 APQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02210 PLN02210
UDP-glucosyl transferase
 292-429 1.94e-09

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 59.66  E-value: 1.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  292 YINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKIPQTVLWRytgTRPSNLANNT------------ILVKWLPQNDL 359
Cdd:PLN02210 262 WLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKI 337

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45827765  360 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENALKAV 429
Cdd:PLN02210 338 LSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERCIEAV 412
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 266-445 4.82e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.50  E-value: 4.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  266 PVMPNMVFIGGINCKKRKDLSQeFEA--------YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIpqTVLWRYT 337
Cdd:PLN02173 224 PTVPSMYLDQQIKSDNDYDLNL-FDLkeaalctdWLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVR 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  338 GTRPSNL---------ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME-TKG 407
Cdd:PLN02173 300 ASEESKLppgfletvdKDKSLVLKWSPQLQVLSNKAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWK 379

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 45827765  408 AGVTLNVLEMTS----EDLENALKAVIN---DKSYKENIMRLSSL 445
Cdd:PLN02173 380 VGVRVKAEKESGiakrEEIEFSIKEVMEgekSKEMKENAGKWRDL 424
PLN02555 PLN02555
limonoid glucosyltransferase
 350-441 5.24e-09

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 58.66  E-value: 5.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  350 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 422
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 45827765  423 ENALKAVINDKS--YKENIMR 441
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN03015 PLN03015
UDP-glucosyl transferase
 225-420 6.07e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 58.17  E-value: 6.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  225 LFSKYEELAS---AVLKRDVDiitlyqkvsvwLLRYDFVLEYP-RPVMPNMVFIggincKKRKDLsqeFEaYINASGEHG 300
Cdd:PLN03015 209 LVNTWEELQGntlAALREDME-----------LNRVMKVPVYPiGPIVRTNVHV-----EKRNSI---FE-WLDKQGERS 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  301 IVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLW------RYTG-----------TRPSNLANNT-----ILVKWLPQND 358
Cdd:PLN03015 269 VVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSYLGasssdddqvsaSLPEGFLDRTrgvglVVTQWAPQVE 347

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45827765  359 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKrMETKGAGVTLNVLEMTSE 420
Cdd:PLN03015 348 ILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNAT-LLTEEIGVAVRTSELPSE 408
PLN03004 PLN03004
UDP-glycosyltransferase
 269-444 1.25e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 57.39  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  269 PNMVFIGGINCKKRKDLSQEFEA-----YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLWryTGTRPSN 343
Cdd:PLN03004 235 RNIYPIGPLIVNGRIEDRNDNKAvsclnWLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPE 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  344 LANNTILVK--------------------WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 403
Cdd:PLN03004 312 LEKTELDLKsllpegflsrtedkgmvvksWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMI 391

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 45827765  404 -ETKGAGVTLNVLE---MTSEDLENALKAVINDKSYKENIMRLSS 444
Cdd:PLN03004 392 vDEIKIAISMNESEtgfVSSTEVEKRVQEIIGECPVRERTMAMKN 436
PLN00164 PLN00164
glucosyltransferase; Provisional
 352-400 1.26e-08

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 57.37  E-value: 1.26e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 45827765  352 KWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 400
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02534 PLN02534
UDP-glycosyltransferase
 349-414 1.35e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.18  E-value: 1.35e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45827765  349 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 414
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 353-400 2.46e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 2.46e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 45827765  353 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 400
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN02562 PLN02562
UDP-glycosyltransferase
 301-442 1.76e-07

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 53.73  E-value: 1.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  301 IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 372
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45827765  373 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 442
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 141-401 2.37e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 53.09  E-value: 2.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  141 ESKFDALFTDPALPCGVILAEYLGLP-------SVYLFrgfpcSLEHTFSRSP-------DP-------VSYIPRCY-TK 198
Cdd:PLN02448 106 EPPVTAIVADTYLFWAVGVGNRRNIPvaslwtmSATFF-----SVFYHFDLLPqnghfpvELsesgeerVDYIPGLSsTR 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  199 FSDHMTFSQRVANFLVNL-LEPYLF-----YCLFSKYEELASAVLKrdvdiiTLYQKVSVWLlrydfvleYP-RPVMPNM 271
Cdd:PLN02448 181 LSDLPPIFHGNSRRVLKRiLEAFSWvpkaqYLLFTSFYELEAQAID------ALKSKFPFPV--------YPiGPSIPYM 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  272 VFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW---RYTGTRPSNLANNT 348
Cdd:PLN02448 247 ELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvarGEASRLKEICGDMG 325

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 45827765  349 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 401
Cdd:PLN02448 326 LVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 263-403 5.04e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 52.11  E-value: 5.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  263 YPrPVMPnmvfIGGINCKKRK-----DLSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW- 334
Cdd:PLN02167 242 YP-PVYP----VGPILSLKDRtspnlDSSDrdRIMRWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLWs 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  335 -RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 401
Cdd:PLN02167 316 iRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNAF 395


                 ..
gi 45827765  402 RM 403
Cdd:PLN02167 396 TM 397
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 350-443 6.17e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 52.10  E-value: 6.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  350 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEM 417
Cdd:PLN02554 346 VIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETV 425

                         90       100
                 ....*....|....*....|....*..
gi 45827765  418 TSEDLENALKAVI-NDKSYKENIMRLS 443
Cdd:PLN02554 426 TAEEIERGIRCLMeQDSDVRKRVKEMS 452
PLN02207 PLN02207
UDP-glycosyltransferase
 240-403 2.98e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 49.65  E-value: 2.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  240 DVDIITLYQKVSVWLLRYDFVLE------------YPRPVMPNMVFIGGINCKKRKDLSQ--EFEAYINASGEHGIVVFS 305
Cdd:PLN02207 202 YVKLAILFTKANGILVNSSFDIEpysvnhfldeqnYPSVYAVGPIFDLKAQPHPEQDLARrdELMKWLDDQPEASVVFLC 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  306 LGSMVSeIPEKKAMAIADALGKIPQTVLWRYTGTRPSN-----------LANNTILVKWLPQNDLLGHPMTRAFITHAGS 374
Cdd:PLN02207 282 FGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddllpegfldrVSGRGMICGWSPQVEILAHKAVGGFVSHCGW 360

                        170       180
                 ....*....|....*....|....*....
gi 45827765  375 HGVYESICNGVPMVMMPLFGDQMDNAKRM 403
Cdd:PLN02207 361 NSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 349-400 3.67e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 49.48  E-value: 3.67e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 45827765  349 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 400
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02208 PLN02208
glycosyltransferase family protein
 353-434 1.09e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 48.09  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  353 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 427
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 45827765  428 AVINDKS 434
Cdd:PLN02208 397 SVMDKDS 403
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 301-445 2.35e-05

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 46.78  E-value: 2.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  301 IVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 366
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  367 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 437
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 45827765  438 NIMRLSSL 445
Cdd:PLN03007 446 RRLRAKKL 453
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 369-449 3.00e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.63  E-value: 3.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765   369 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 444
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 45827765   445 LHKDR 449
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 300-464 5.79e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 5.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  300 GIVVFSLGSMVSEIPEKKAMAIADALgkiPQTVLWRYTGtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE 379
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  380 SICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEP 453
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSP 424

                        170
                 ....*....|.
gi 45827765  454 LDLAVFWVEFV 464
Cdd:PLN00414 425 GLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 369-443 8.61e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.90  E-value: 8.61e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 369 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 440
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 45827765 441 RLS 443
Cdd:cd03785 337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 369-443 1.84e-04

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.96  E-value: 1.84e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 369 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 440
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 45827765 441 RLS 443
Cdd:COG0707 343 ALA 345
PLN02764 PLN02764
glycosyltransferase family protein
 353-441 2.11e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.90  E-value: 2.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765  353 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 427
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 45827765  428 AVINDKSYKENIMR 441
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 349-410 2.95e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 43.35  E-value: 2.95e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45827765  349 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 410
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 369-441 1.43e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.88  E-value: 1.43e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 45827765  369 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 441
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 357-442 1.85e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 1.85e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827765 357 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 435
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 45827765 436 KENIMRL 442
Cdd:cd17507 340 SEAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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